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© 2026 Wu Tsai Neurosciences Institute, Stanford University
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This award-winning show from Stanford’s Wu Tsai Neurosciences Institute is a field manual for anyone who wants to understand their own brain and the new science reshaping how we learn, age, heal, and make sense of ourselves.
Each episode, host Nicholas Weiler sits down with leading scientists to unpack big ideas from the frontiers of the field—brain-computer interfaces and AI language models; new therapies for depression, dementia, and stroke; the mysteries of perception and memory; even the debate over free will. You’ll hear how basic research becomes clinical insight and how emerging tech might expand what it means to be human. If you’ve got a brain, take a listen.
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Today on the show, we explore the complex biology underlying a seemingly straightforward question: How do our brains stay healthy – or not – as we age? There seems to be a constant flow of new secrets to healthy brain aging – inflammation, estrogen levels, how the brain clears out its waste. We've talked about many of these explanations on the show, and it can be easy to think that whatever the latest one is, that's the one. At least until the next one comes along. In reality, each of those t...
Today on the show, we bring you a conversation with Carolyn Bertozzi, the Baker Family Director of Sarafan ChEM-H and the Anne T. and Robert M. Bass Professor in the School of Humanities and Sciences. Bertozzi is a Nobel Laureate, a MacArthur Fellow, and an all around cool person – although it didn't come up in the conversation, she used to play in a band with Rage Against the Machine's Tom Morello. Although Bertozzi wouldn’t call herself a neuroscientist — she’s a chemist at heart – he...
Health influencers and scientists have both gone crazy for peptides. The peptide health craze stems from a lot of online hype — centered on gray-market compounds that haven't been rigorously tested in humans and aren't regulated for safety or purity. But among scientists, there is a genuine "revolution" underway — spurred by technological developments revealing an order of magnitude more peptides in our bodies than we ever realized, and by the unexpected and unparalleled success of GLP-1 dr...
Transcranial magnetic stimulation (TMS) is one of the most promising new technologies in psychiatry. Essentially, it allows us to reach inside the brain, stimulate it, and alter the brain circuits that go awry in disorders like depression. As the late Nolan Williams once explained, we've known for a long time that mental health disorders are caused by changes in electrical circuits in our brains, until TMS came along, we didn't had a good way of nudging those circuits back toward health...
Back in the 1950s, doctors didn't know a whole lot about the heart. If someone came in with chest pain, clinicians would ask a few questions, then take a stab at treating what might be heartburn or a heart attack. That's where mental health care is today, according to today's guest, Leanne Williams. For example: you come into a psychiatrist’s office. The psychiatrist determines that you’ve experienced five or more depressive symptoms for at least two consecutive weeks and you get a diag...
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