LONGEVITY with Nathalie Niddam

Today, I'm joined by the wonderful Dr. Shivani Gupta, a true force in bridging ancient Ayurvedic wisdom with cutting-edge modern research on inflammation and healthy aging. She recently authored The Inflammation Code. Dr. Shivani opens up about her deeply personal motivation—from witnessing her grandfather's preventable health decline to spending years in both traditional and scientific studies, ultimately earning a PhD focused on turmeric and chronic inflammation. For Dr. Shivani's Turmeric and sleep gummies visit https://fusionaryformulas.com/?sca_ref=9671225.dtSyos3QQx1c and use code NAT15 for 15% off.   Episode Timestamps: Welcome & Introduction to Longevity Podcast ... 00:00:00 Autophagy & Spermidine Supplementation ... 00:02:41 Personal Connection & Product Experience ... 00:03:46 Health Declines in Modern Indian Culture ... 00:07:47 Reversing Disease: Ayurveda & Biohacking ... 00:11:11 Discovering Ayurveda & Turmeric's Power ... 00:15:12 Turmeric vs. NSAIDs: Scientific Support ... 00:19:52 PPIs, Gut Health, and Curcumin ... 00:21:26 Inflammation as the Root of Chronic Disease ... 00:23:24 Sleep Rituals & Circadian Timing ... 00:28:59 Elemental Design / Doshas Explained ... 00:32:13 Aligning Lifestyle with Dosha for Health ... 00:42:46 Mental Inflammation: Stress & Burnout ... 00:46:00 Turmeric Science, Uses & Myths ... 00:54:20 Personalized Spice Use & Dosha Guidance ... 01:03:48 Top Spices for Longevity ... 01:07:44 Cautions: Medications & Turmeric ... 01:10:03 The Future of Inflammation in Medicine ... 01:11:11 Rapid-Fire Longevity Habits ... 01:15:03   Our Amazing Sponsors: Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset without suffering. Go  to lvluphealth.com and use code NAT for 20% off.   Primeadine by Oxford Healthspan — A food-derived spermidine supplement that supports autophagy and cellular renewal without fasting, made from Japanese wheat germ with clean, rigorously tested ingredients (including a gluten-free option); visit oxfordhealthspan.com/BIONAT20 and use code BIONAT20 at checkout.   Gut Essentials Bundle by Just Thrive — A powerful duo of a clinically proven probiotic and digestive bitters to reduce bloat, boost energy, curb cravings, and help you feel your best fast, backed by a 100% money-back guarantee — Take the Feel Better Challenge and save 20% at JustThriveHealth.com/NAT20 with promo code NAT20.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined by the inspiring Dr. Jeffrey Gladden—a trailblazer in longevity medicine who once spent decades as an interventional cardiologist, only to challenge everything he knew after his own health hit a wall. Dr. Gladden opens up about the moment he refused to accept "normal for your age" as a diagnosis, launching himself into the world of functional and age-management medicine to reclaim his vitality and help others do the same.   Episode Timestamps: Welcome and episode introduction ... 00:00:00 Health crisis and discovering personal optimization ... 00:07:05 From "sick care" to health optimization ... 00:10:46 Vision for personalized, youthful longevity ... 00:12:17 Personalized medicine: why one size doesn't fit all ... 00:16:00 Linear versus exponential aging; fixing a flawed approach ... 00:18:02 Five circles of exponential health: key longevity domains ... 00:19:23 Curiosity, growth mindset, and quantum thinking in longevity ... 00:22:22 Why individualization is crucial for diet and interventions ... 00:28:52 Insulin resistance: the hidden driver of aging ... 00:33:41 Environmental and internal (psychospiritual) factors in health ... 00:38:40 Healing through meditation, stress management, and flow ... 00:41:15 Robustness, resilience, and anti-fragility as longevity superpowers ... 00:57:09 Safe, personalized hormone therapy and the importance of tracking ... 01:03:33 Integrating mindset, purpose, and psycho-spiritual work ... 01:08:50 Peptides and advanced therapies: preparing for optimal results ... 01:09:56 Common test misconceptions in longevity medicine ... 01:12:56 Debunking the myth of single biological age ... 01:16:38 Resources, connect with Dr. Gladden, and closing ... 01:18:09   Our Amazing Sponsors: Youth Daily by Young Goose — An all-in-one moisturizer powered by NAD+ nano precursors to boost elasticity, smooth wrinkles, and keep your skin looking fresh, dewy, and full of life; grab yours at younggoose.com and use code Nat10 for first orders or 5NAT for returning customers.   Quantum Upgrade - Supports nervous system balance without wearables or apps—just effortless, 24/7 quantum energy streaming. With 21+ studies showing measurable improvements in stress and cellular function, it's easy to try for yourself. Visit quantumupgrade.io/NAT and use code NAT10 to start the free trial.   Mitopure®️ Longevity Gummies by Timeline — Clinically backed Urolithin A supports mitochondrial health to boost energy, recovery, and healthy aging, all in an easy daily gummy instead of another pill; go to timeline.com/nat20 for 20% off Mitopure®️ Gummies.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm sitting down with Dr. Gus Vickery, a good friend and one of my favorite collaborators when it comes to cutting-edge insights in personalized health and longevity. In this episode, I put myself under the microscope as we walk through my own metabolomics testing after a period of heavy travel, stress, and—yes—a break from my usual supplement routine. If you've ever wondered whether skipping your foundational health habits "just for a little while" really matters, you're about to find out. If you are a clinician and would like to offer the Aristotle test to your patients please use this link to learn more about the Theriome test: therio.me/niddam  If you are a patient and would like to run the Theriome Aristotle test and get a full interpretation and protocol based on your results from Dr Vickery & his team please use this link: https://authentichealth.com/precision-health-evaluation/   Episode Timestamps: Introduction to Longevity Podcast and episode overview ... 00:00:00 Metabolomics and interpreting health data – practitioner guidance needed ... 00:05:05 Combining metabolomics, gut, and blood data for whole-system insights ... 00:06:02 Nutrient depletion and oxidative stress: critical findings ... 00:18:57 Supplementation essentials for aging well ... 00:27:05 Metabolomics comparison by age group and optimization goals ... 00:29:03 Stacking interventions: why less is more with diagnostics ... 00:31:05 Functional health markers and the value of context ... 00:34:47 Sympathetic dominance, mindset, and impact on longevity ... 00:35:26 Restoring nervous system balance – inner work and tech tools ... 00:42:38 Toxins, heavy metals, and practical detox strategies ... 00:49:11 Clean environment, resiliency, and realistic lifestyle shifts ... 00:55:29 Key nutrient deficiencies revealed by metabolomics ... 01:09:15 Genetic and metabolomic tests: what's actionable? ... 01:15:07 Hope for the future: human resilience and expanding technology ... 01:22:24 Weekly actionable: walk outside for mitochondria and stress relief ... 01:26:55   Our Amazing Sponsors: Cozy Earth – Thoughtfully designed bedding and bath essentials that turn your home into a calm, elevated retreat and actually hold up wash after wash. Give your space a reset at cozyearth.com with code LONGEVITY for up to 20% off, and don't forget to mention this podcast in the post-purchase survey.   Nature's Marvels Bioregulators - provide gentle, organ-specific support — and the Liver Bioregulator is a favorite this season for supporting detox pathways and metabolic flow. Head to profound-health.com and use code NAT15 for 15% off your first order. Blue Peptide Spray from Young Goose brings the message back loud and clear. With NAD+ APEX to refuel energy, methylene blue to recharge your mitochondria, and GHK-Cu to tell your skin, "Hey, start making that collagen again!" It's longevity science, not cosmetic hype. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined by the remarkable Dr. Gabrielle Lyon, a pioneer in redefining the longevity conversation by making muscle health—not weight—the centerpiece of aging well. With a background in geriatrics and nutritional sciences, she illuminates why the quality of your muscle tissue is a far more powerful predictor of health than any number on the scale. Her perspective challenges the notion of a "healthy sedentary person" and reveals the major role of intramuscular fat in metabolic dysfunction. Check out her book The Forever Strong Playbook.    Episode Timestamps: Introduction, podcast focus, and welcoming Dr. Gabrielle Lyon ... 00:00:00 Muscle's impact on brain health, inflammation, and healthy aging ... 00:01:03 Dr. Lyon's childhood, grit, and self-discipline ... 00:04:33 Mentorship and protein science under Dr. Donald Lehman ... 00:07:05 Muscle as the overlooked metabolic organ ... 00:08:45 Why intramuscular fat matters more than body weight ... 00:10:06 Plant vs. animal protein for muscle health ... 00:13:29 Muscle as an endocrine organ and cognition ... 00:16:21 Future of muscle science: anabolics, imaging, and technology ... 00:18:22 GLP-1s, sarcopenic obesity, and muscle-first protocol ... 00:46:45 Sarcopenia, aging, and the importance of early training ... 01:04:35 Building lifelong resilience—mental and physical ... 01:08:31 Predictions: anabolics, muscle testing, and assessment ... 01:12:17 "Strength is a responsibility, not a luxury" ... 01:13:53   Our Amazing Sponsors: Cozy Earth – Thoughtfully designed bedding and bath essentials that turn your home into a calm, elevated retreat and actually hold up wash after wash. Give your space a reset at cozyearth.com with code LONGEVITY for up to 20% off, and don't forget to mention this podcast in the post-purchase survey.   Ozlo - use smart sound engineering and sleep detection to help you stay in deeper, more stable sleep all night. Create your ideal sleep environment anywhere: go to ozlosleep.com/nat and use code NAT to get $75 off. Tranq Dart by Wizard Sciences - a multi-pathway sleep support from Wizard Sciences. It's not a knockout pill; it's a gentle nudge toward that wind-down zone. I take it about 30 minutes before bed, and it helps my body and brain sync up for sleep. Visit wizardsciences.com and use code NAT15 for 15% off. Sleep smarter, not harder.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators.   Use code NAT10 for 10% off products at https://alchemiqlabs.com/   Episode Timestamps: Welcome and episode introduction ... 00:00:00 Anthony Castore's path from strength coaching to cellular medicine ... 00:05:55 Connecting strength training with cellular pathways (AMPK, mTOR) ... 00:12:27 Explaining and balancing AMPK and mTOR for performance ... 00:13:03 Training strategies: Metabolic, hypertrophy, and neural approaches ... 00:18:18 Building a solid foundation: Lifestyle, training, nutrition, peptides ... 00:23:04 Assessing recovery capacity and individualizing protocols ... 00:26:02 Mitochondrial fission, fusion, and targeted adaptation ... 00:29:57 Optimizing muscle gain and fat loss through calories and recovery ... 00:31:00 Differentiating bodybuilder vs. longevity approaches ... 00:34:44 Integrating peptides and support molecules into routines ... 00:40:44 Ketone esters and mitochondrial peptide interventions ... 00:41:20 Cautions on stacking and combining interventions ... 00:54:04 Lessons learned from overdoing interventions ... 01:05:02   Our Amazing Sponsors: Vitali - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off.   BEAM Minerals - Low energy often starts in the mitochondria. Support cellular energy with a bioavailable liquid mineral supplement — and get 20% off at beamminerals.com with code NAT20.   Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset after the holidays without suffering. Go to lvluphealth.com and use code NAT for 20% off.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined by the deeply thoughtful and refreshingly honest Dr. Sanjay Bhojraj, a self-described "curious cardiologist" who spent decades treating heart attacks in the cath lab — before stepping away to ask a bigger question: Why are we waiting for the crisis instead of preventing it?   Episode Timestamps: Welcome to Longevity & episode setup … 00:00:00 Dr. Bhojraj's shift from ER cardiology to prevention … 00:06:30 Why most heart attacks aren't caused by big blockages … 00:09:15 Stress, nervous system load & heart attack risk … 00:13:10 CIMT explained: what it measures (and what it misses) … 00:26:40 Calcium scores vs CT angiograms … 00:35:45 CLEERLY scan: seeing dangerous soft plaque … 00:38:45 Can plaque actually regress? … 00:41:55 When heart scans make patients less afraid … 00:44:05 When should you test — even without symptoms? … 00:45:50 Why age 45 is a major cardiovascular inflection point … 00:47:10 Hormones, estrogen loss & women's heart risk … 00:50:10 Why cardiology still misunderstands women … 00:54:30 Small dense LDL, ApoB & oxidized cholesterol … 01:02:00 Why fixing inflammation matters more than numbers … 01:05:50   Our Amazing Sponsors: Regenerive - Built around clinically validated Longufera (Ash X4) to support core aging pathways—so it's not just "healthy aging" in theory. Go to regenerive.co and use code NAT25 to save 25%   Mitopure® Longevity Gummies are the only clinically proven Urolithin A gummies supporting mitochondrial health — one of the key hallmarks of aging. Get 35% off a one-month subscription at Timeline.com/Nat2026 *Special deal through January 2026.   PW1 by Puori — A clean, high-quality whey protein that's third-party tested for over 200 contaminants and smooth enough to feel like a treat while supporting muscle, metabolism, and bone strength. Go to puori.com/NAT and use code NAT for 32% off your first subscription or 20% off anything on the site.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined by Charles Bohdy, a true innovator in water purification technology, and Victor Sagalovsky, a passionate advocate for bringing the science of water quality into our daily lives. Together, we take a deep dive into the unseen world of the water running through our homes—exploring not just its purity, but its hidden potential to support our biology in ways most of us have never considered. Whole HOME Water System - Use code NAT100   Episode Timestamps: Intro to Longevity Podcast and today's water focus ... 00:00:00 Water system's health benefits and testing ... 00:01:33 Why water quality is overlooked yet critical ... 00:07:20 Common water issues and municipal limitations ... 00:09:10 Filtration methods: carbon blocks and pathogens ... 00:15:26 Charles's nano-ceramic multilayer filters ... 00:20:14 Concerns with chlorine and fluoride in water ... 00:23:44 Retaining healthy minerals: charge-based filtration ... 00:35:18 Reverse osmosis: pros, cons, and fungal risks ... 00:50:49 Structured water's role in biological health ... 00:56:53 Water structuring: agricultural validation ... 01:00:21 Whole-home filtration: installation and costs ... 01:11:02 Closing thoughts: bringing nature's water home ... 01:25:00   Our Amazing Sponsors: Regenerive - Built around clinically validated Longufera (Ash X4) to support core aging pathways—so it's not just "healthy aging" in theory. Go to regenerive.co and use code NAT25 to save 25%  Primeadine by Oxford Healthspan: Primeadine supports autophagy — your cells' natural renewal and cleanup process — using food-derived spermidine, no fasting required. If you want to support resilience from the inside out, head to https://www.oxfordhealthspan.com/BIONAT20 and use code BIONAT20 at checkout (one-time purchases only). Ozlo - use smart sound engineering and sleep detection to help you stay in deeper, more stable sleep all night. Create your ideal sleep environment anywhere: go to ozlosleep.com/nat and use code NAT to get $75 off.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined by Ben Katz—better known online as Mr. Mass Spec —an academic analytical chemist from UC Irvine whose mission is to uncover what's really in our everyday foods, drinks, and products. Ben reverse engineers everything from Taco Bell meat to Doritos, and sometimes even entire industries, using cutting-edge mass spectrometry. His curiosity and expertise have made him a go-to source for those wanting to know what's hiding behind vague ingredient labels and "natural flavors."   Episode Timestamps: Welcome and podcast introduction ... 00:00:00 What is mass spectrometry? ... 00:05:00 Viral "what's in it?" projects and public interest ... 00:07:27 Synthetic vs. plant-derived nicotine and toxins in plant extracts ... 00:09:53 Food label transparency and loopholes (natural flavors, FEMA, GRAS) ... 00:20:11 Sweeteners & artificial additives: sucralose, stevia, cost motivations ... 00:23:07 Ultra pasteurization of milk and added flavors ... 00:29:48 Chocolate, caffeine content, and labeling challenges ... 00:33:12 Industrial food processes, GMOs, and food security insights ... 00:38:36 Microplastics: occurrence, regulation, and PEG in food ... 00:50:15 Supplements under development for microplastic removal ... 00:58:43 Adulteration in olive oil, maple syrup, and honey ... 01:04:08 Hidden sweeteners, and processed food pitfalls ... 01:10:14 Avoid artificial sweeteners, problematic plastics, and hidden flavors ... 01:14:36   Our Amazing Sponsors: Manukora Honey - rich, creamy Manuka honey packed with powerful bioactives, all in just one heaped teaspoon a day. Go to MANUKORA.com/NAT to save up to 31% plus $25 in free gifts with the Starter Kit.   Magnesium Breakthrough - uses seven absorbable forms of magnesium to support deeper sleep, calmer nerves, and real recovery. Get up to 35% off at bioptimizers.com/bionat with code BIONAT.   Nature's Marvels Bioregulators - provide gentle, organ-specific support — and the Liver Bioregulator is a favorite this season for supporting detox pathways and metabolic flow. Head to profound-health.com and use code NAT15 for 15% off your first order.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm kicking off the new year with a back-to-basics deep dive into one of the most pivotal yet overlooked foundations of longevity: gut health. Over the past episodes, we've explored everything from gene therapy to advanced tech, but it all comes back to the habits and systems we rely on every single day—and the gut is right at the center of that equation.   Episode Timestamps: Gut health as the cornerstone of longevity ... 00:00:00 Why disease and wellness begin in the gut ... 00:03:46 Symptoms and signs of gut imbalance ... 00:08:53 Normalizing digestive discomfort ... 00:09:33 Key stressors for gut health: stress, poor food choices ... 00:12:03 How chronic stress disrupts digestion ... 00:12:59 Processed foods, toxins, and nutrient deficiencies ... 00:13:14 The importance of whole foods, healthy fats, and cooked veggies ... 00:14:27 Testing and understanding your own food tolerances ... 00:16:31 Risks of dehydration, overtraining, and PPIs ... 00:19:24 Structure of a healthy gut: digestion, gut barrier, organ support ... 00:23:19 Pre-meal rituals for better digestion ... 00:25:33 Choosing and introducing probiotics and fiber ... 00:37:44 Tracking your food and gut motility ... 00:42:12 Lifestyle habits: exercise, sleep, stress, meal timing ... 00:45:00 Avoiding snacking and late meals ... 00:49:05 Remove offenders, restore with enzymes, replenish with probiotics ... 00:50:12 Bone broth, anti-inflammatory foods, and gut repair ... 00:54:19 Peptides and bioregulators for organ optimization ... 00:57:03   Our Amazing Sponsors: Tranq Dart by Wizard Sciences - a multi-pathway sleep support from Wizard Sciences. It's not a knockout pill; it's a gentle nudge toward that wind-down zone. I take it about 30 minutes before bed, and it helps my body and brain sync up for sleep. Visit wizardsciences.com and use code NAT15 for 15% off. Sleep smarter, not harder.   Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset after the holidays without suffering. Go  to lvluphealth.com and use code NAT for 20% off.   Vitali - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined by the insightful Ashley Koff, renowned registered dietitian and fierce advocate for personalized, realistic nutrition that actually works in the real world. In this episode, Ashley Koff opens up about her personal and professional journey—from her early days in big brand marketing (think sugared cereals and infobesity) to her pivotal "aha" moments that led her to champion true weight health, not just weight loss.   Episode Timestamps: Welcome and introduction to the Longevity Podcast ... 00:00:00 Personal experiences shaping nutrition philosophy ... 00:05:59 Influence of marketing on nutrition decisions ... 00:09:01 Big revelations: digestion, GLP-1, and health ... 00:16:43 The power of personalization in nutrition ... 00:19:59 The "Mr. Pizza Pop" case and behavioral change ... 00:23:03 Digestion as the foundation before diet quality ... 00:27:05 Dangers of generic "healthy diet" advice ... 00:36:01 GLP-1 medications: promise, risks, and prerequisites ... 00:40:10 Who truly needs GLP-1 versus lifestyle change alone ... 00:43:09 Muscle, bone, and shifting focus to building health ... 00:51:30 Nutrient intake, fiber, and supplement personalization ... 00:55:11 Digestive enzymes and optimizing digestion ... 01:03:10 Food noise, satiety, and psychological freedom ... 01:07:29 Ongoing assessment: tracking weight, fat, muscle ... 01:15:19 Weaning off GLP-1 and the importance of professional support ... 01:18:32   Our Amazing Sponsors: Primeadine by Oxford Healthspan: Primeadine supports autophagy — your cells' natural renewal and cleanup process — using food-derived spermidine, no fasting required. If you want to support resilience from the inside out, head to https://www.oxfordhealthspan.com/BIONAT15 and use code BIONAT15 at checkout (one-time purchases only).   Magnesium Breakthrough by BiOptimizers: Better sleep isn't about willpower — it's about absorption. Magnesium Breakthrough uses seven real forms of magnesium that help you rest deeper and recover faster. Get up to 35% off at bioptimizers.com/bionat with code BIONAT.   Just Thrive Gut Essentials Bundle: pairs a probiotic proven to arrive 100% alive with digestive bitters that support digestion and curb cravings, so you actually feel the difference fast. Save 20% on your first Gut Essentials Bundle at justthrivehealth.com/NAT20 with code NAT20 — 100% money-back guarantee.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm excited to bring back the always thought-provoking Joel Greene, author of "The Immunity Code" and "The Way," for a fresh conversation on why true longevity is about so much more than how much muscle you have or the latest diet trend you're following. Joel Greene opens up about the hard lessons he's learned from decades of self-experimentation and reveals why chasing that ideal gym physique might actually backfire as you age.   Episode Timestamps: Welcome & episode introduction ... 00:00:00 The evolving nature of health and homeostasis ... 00:08:29 Beware rigid diet tribes—find nutritional flexibility ... 00:21:41 Biomarkers people miss: fasting insulin and acyl carnitines ... 00:23:11 Chronic ketosis, ATP, and metabolic slowdowns ... 00:25:16 Myth-busting muscle and the limits of bodybuilding for aging ... 00:27:17 Functional movement, flexibility, and big toe strength ... 00:34:29 Simple foundation: daily jumps or hops ... 00:47:41 Sensible protocols for muscle gain after 50 ... 01:00:07 Balance in diet as the true key to insulin sensitivity ... 01:08:06 Rules of thumb: meal timing for insulin ... 01:15:56 Stillness, faith, and feeding your spirit ... 01:21:56 Most abused supplement: Antioxidants ... 01:27:54 Body fat percentage as top longevity marker ... 01:29:12   Our Amazing Sponsors: Quantum Upgrade - Supports nervous system balance without wearables or apps—just effortless, 24/7 quantum energy streaming. With 21+ studies showing measurable improvements in stress and cellular function, it's easy to try for yourself. Visit quantumupgrade.io/NAT and use code NAT10 to start the free trial.   Blue Peptide Spray from Young Goose - Brings the message back loud and clear. With NAD+ APEX™️ to refuel energy, methylene blue to recharge your mitochondria, and GHK-Cu to tell your skin, "Hey, start making that collagen again!" It's longevity science, not cosmetic hype. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer.   Mitopure® Longevity Gummies are the only clinically proven Urolithin A gummies supporting mitochondrial health — one of the key hallmarks of aging. Get 35% off a one-month subscription at Timeline.com/Nat2026 *Special deal through January 2026.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined by a lineup of trailblazers in the science of longevity: Ben Azadi, Dr. Teo Soleymani, Dr. Carrie Jones, Ian White, Dr. Robert Lufkin, and Dr. Jenn Simmons . Together we dig into some of the most persistent myths and cutting-edge research shaping how we age—including why "eat less, move more" misses the mark, what really causes skin cancers, breast cancer screening risks, and the often-overlooked ripple effects of perimenopause.   Links to full episodes: #333: Keto Myths, Carb Days, and Why Calories Don't Count | Ben Azadi on Breaking the Weight Loss Cycle Episode 338: How the Sun ACTUALLY Impacts Skin Aging and Cancer Risk: Skin Cancer Controversies, Sun Safety Secrets, and Anti-Aging Breakthroughs With Teo Soleymani, MD Episode 376: Survival Tips for Perimenopause, NEW At-Home Hormone Testing & Bioidentical Myths With Dr. Carrie Jones Episode 350: Nature's Longevity CODE Revealed: Exosomes, Plasma HACKS & the Real Science of Aging | With Dr. Ian White Episode 318: Lies He Taught In Medical School: The METABOLIC Secret To Reversing Chronic Disease with Dr. Robert Lufkin Episode 300: Breast Cancer Overdiagnosis, Mammogram Myths, The REAL Risks For Women And Bold NEW Alternatives With Dr. Jenn Simmons   Episode Timestamps: Welcome & podcast overview ... 00:00:00 Longevity habits handout & sponsor plug ... 00:00:48 Clean protein choices & contamination risks ... 00:01:25 Calorie focus vs. hormones in weight loss ... 00:02:42 Why calories in/calories out fails ... 00:03:27 Cellular inflammation & gut microbiome in weight ... 00:04:43 Healthy, flexible metabolism over fast metabolism ... 00:07:51 Sun exposure, genetics & skin cancer ... 00:08:02 Sunscreen myths & ingredient safety ... 00:11:47 Perimenopause symptoms beyond hot flashes ... 00:12:27 Hormone replenishment: lifestyle + medical strategies ... 00:15:35 Breaking menopause myths & self-education ... 00:19:05 Blood factors & parabiosis in aging ... 00:21:37 Plasma exchange — practical and scientific updates ... 00:26:01 Western medicine vs. chronic disease reality ... 00:28:07 Breast cancer screening & over-treatment concerns ... 00:33:16 Hormone therapy after menopause—timing & benefits ... 00:37:07   Our Amazing Sponsors: PW1 protein powder is third-party tested for more than 200 contaminants, and Puori was the only brand that earned the Clean Label Project Transparency Certificate. That level of disclosure is rare. And refreshing. If you want protein that supports your goals — without the guesswork — go to Puori.com/NAT and use code NAT for 32% off your first subscription or 20% off anything on the site. Manukora - Now in NEW Glass Jars - This isn't regular honey. Manukora's bees collect nectar from the Manuka tea tree, which packs 3x more antioxidants and prebiotics than normal honey. Plus it naturally contains MGO, that rare antibacterial compound. Head to MANUKORA.com/NAT to save up to 31% plus get $25 worth of free gifts with the Starter Kit.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined by Lucas Aoun, from Australia, supplement formulator, and self-described human guinea pig. Lucas and I dive into his personal journey from working behind the counter at his father's pharmacy, to experimenting with early nootropic formulas, and ultimately becoming a sought-after educator in the world of biohacking.   Episode Timestamps: Podcast introduction and guest welcome ... 00:00:00 Lucas Aoun's journey into biohacking ... 00:04:13 Innovative supplement formulation and teacrine ... 00:10:00 Dopamine's role in motivation and productivity ... 00:32:09 Bioindividual supplement responses and AI in health ... 00:17:00 Alcohol alternatives and social nootropics ... 00:39:52 Optimizing exercise timing and performance ... 00:48:49 Testosterone, thyroid, and men's health fundamentals ... 00:53:01 Diet diversity: carnivore, vegan, and healthy fats ... 00:59:19 Catwaba Pure: origins, benefits, and uses ... 01:13:12   Our Amazing Sponsors: Nootropept by LVLUP - an advanced cognitive enhancement formula that combines fast-acting neuropeptides, cholinergic support, and mitochondrial-boosting compounds to sharpen mental clarity, memory, and long-term brain performance. Visit https://lvluphealth.com/ and use code NAT at checkout for 20% off.   PW1 protein powder is third-party tested for more than 200 contaminants, and Puori was the only brand that earned the Clean Label Project Transparency Certificate. That level of disclosure is rare. And refreshing. If you want protein that supports your goals — without the guesswork — go to Puori.com/NAT and use code NAT for 32% off your first subscription or 20% off anything on the site.   NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It's about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you'd get from a glass of pomegranate juice. Visit Timeline.com/nat20 and use code nat20 for 20% off your purchase.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, it's just me, and we're doing things a little differently on the Longevity Podcast. With the intensity of the holiday season winding down, I wanted to take a step back from the usual deep-dives and high-tech hacks to focus on something fundamental—free, practical strategies to help you manage stress. Chronic stress is sneaky in how it accelerates aging, impacts your telomeres, and undoes even the most powerful interventions, but thankfully, there are simple ways we can start to turn things around.   Episode Timestamps: Welcome and episode introduction ... 00:00:00 Immune support with bioregulators ... 00:00:40 Why focus on free stress management tools ... 00:01:54 How chronic stress accelerates aging ... 00:04:32 Stress undermining longevity interventions ... 00:05:13 The importance of nervous system balance ... 00:06:50 Recognizing hidden stress and using HRV ... 00:07:45 When to seek further medical help ... 00:09:46 Recap: chronic stress shortens your healthspan ... 00:10:21 10 free strategies to manage stress ... 00:12:25 Connection and volunteering ... 00:13:15 Break the doom scrolling habit ... 00:17:37 Benefits of time in nature ... 00:20:02 Exercise for resilience ... 00:22:41 Breath work and vagus nerve support ... 00:25:33 Practicing gratitude daily ... 00:31:33 The power of sleep ... 00:34:30 Taking time for yourself ... 00:35:19   Our Amazing Sponsors: Nature's Marvels by Profound Helath - The Thymus Bioregulator helps keep immune response balanced and small human studies in older adults link it with healthier immune markers and fewer seasonal respiratory issues. The Pineal Bioregulator supports your natural melatonin/circadian rhythm—key when schedules and daylight change—so you get the kind of sleep that underpins immune resilience. Head to profound-health.com and use code NAT15 for 15% off your first order.   Fatty15: C15 is 3x more effective than omega-3 and totally vegan. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/NATNIDDAM and using code NATNIDDAM at checkout.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined by Dr. James Hardt—founder of Biocybernaut and a true pioneer in the world of neurofeedback. With over four decades spent mapping how our brainwaves shape emotions, performance, and even identity, Dr. Hardt has helped reframe the conversation around unlocking human potential, making cutting-edge brain training accessible to seekers, creatives, and everyday biohackers alike. Download a FREE copy of his book "The Art of Smart Thinking" at www.biocybernaut.com/bonus   Episode Timestamps: Intro to Longevity Podcast and host ... 00:00:00 Introduction to Dr. James Hardt and neurofeedback ... 00:00:34 Alpha brain waves: effects on trauma, creativity, IQ, EQ, and longevity ... 00:00:57 Biocybernaut and personal experience ... 00:00:49 Overview of neurofeedback basics and early challenges ...00:12:14 Brainwave types explained (delta, theta, alpha, etc.) ... 00:22:12 Importance of alpha training ... 00:29:37 Neurofeedback benefits: creativity, IQ, EQ, and emotional trauma ... 00:39:34 Alpha waves, aging, and longevity ... 00:46:58 Accessible strategies to boost alpha ... 00:51:55 Subconscious mind, ego, and forgiveness work ... 00:58:02 Case studies and health breakthroughs ... 01:01:27 Future of neurofeedback: AI and accessibility ... 01:05:53 Personal transformation and closing remarks ... 01:14:22   Our Amazing Sponsors: Tro Mune by Troscriptions - Cold season doesn't have to take you out. I use Tro Mune—a nightly buccal troche with 75 mg cordycepin—to build immune resilience while I sleep. Take ½–1 before bed, and use it before you get sick or right when you feel it. Troscriptions.com, use NAT10, and get 10% off your first order.   Tranq Dart by Wizard Sciences - a multi-pathway sleep support from Wizard Sciences. It's not a knockout pill; it's a gentle nudge toward that wind-down zone. I take it about 30 minutes before bed, and it helps my body and brain sync up for sleep. Visit wizardsciences.com and use code NAT15 for 15% off. Sleep smarter, not harder. Blue Peptide Spray from Young Goose brings the message back loud and clear. With NAD+ APEX to refuel energy, methylene blue to recharge your mitochondria, and GHK-Cu to tell your skin, "Hey, start making that collagen again!" It's longevity science, not cosmetic hype. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm sitting down with the irrepressible Siggi Clavien, renowned biotech innovator and founder of De-liver-ance, a groundbreaking formula for liver health. Siggi's story is deeply personal—motivated by the loss of loved ones to liver disease, he's made it his life's mission to demystify liver health and help others avoid the fate that touched his own family.   Visit http://loveyourliver.com/NAT code: NAT for 5% off   Episode Timestamps: Introduction and podcast themes ... 00:00:00 Eastern vs. Western liver views ... 00:07:09 Why liver health is central to longevity ... 00:09:28 Hidden toxins: everyday exposures ... 00:12:10 Emotional toxicity and liver ... 00:16:06 Imaging vs. blood tests for liver health ... 00:17:22 Fatty liver trends, risk factors, and children ... 00:20:24 Cirrhosis: new causes, gallbladder link ... 00:25:21 Diet, drugs, and detox ... 00:30:07 Supporting detox daily ... 00:33:39 Fatty liver, metabolism, and key nutrients ... 00:36:41 Liver's impact on mood, brain, hormones ... 00:44:22 Menopause, hormones, and the liver ... 00:47:43 Supplements, packaging, and hidden chemicals ... 00:56:07 Fasting, microplastics, and weight loss stress ... 00:59:29 Deliverance formula: development and benefits ... 01:08:06 Guidance for using Deliverance ... 01:24:04 Core habits: hydration, alcohol, diet soda ... 01:25:39   Our Amazing Sponsors: Blue Peptide Spray from Young Goose: brings the message back loud and clear. With NAD+ APEX to refuel energy, methylene blue to recharge your mitochondria, and GHK-Cu to tell your skin, "Hey, start making that collagen again!" It's longevity science, not cosmetic hype. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer.   Fatty15: C15 is 3x more effective than omega-3 and totally vegan. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/NATNIDDAM and using code NATNIDDAM at checkout.   Nature's Marvels from Profound Health: The Thymus Bioregulator helps keep immune response balanced and small human studies in older adults link it with healthier immune markers and fewer seasonal respiratory issues. The Pineal Bioregulator supports your natural melatonin/circadian rhythm—key when schedules and daylight change—so you get the kind of sleep that underpins immune resilience. Head to profound-health.com and use code NAT15 for 15% off your first order.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined once again by the incredible Dr. Bill Lawrence, a true pioneer in the field of longevity research and one of the most requested guests on this podcast. Dr. Lawrence trained directly with Professor Vladimir Khavinson—the scientist who discovered and developed bioregulator peptides—and has spent the last eight years leading some of the most exciting field research in this space.   Episode Timestamps: Welcome and introduction to Longevity Podcast ... 00:00:00 Origins and early use of bioregulator peptides in Soviet research ... 00:05:39 Organ-specific peptide mechanisms and targeting ... 00:08:28 Dr. Lawrence's collaboration with Professor Cavinson ... 00:12:17 Overview of American clinical studies and study protocols ... 00:14:13 Measuring biological age: telomeres and epigenetic markers ... 00:15:06 Key Russian studies and impact of peptides on mortality ... 00:17:00 Peptides as ultimate epigenetic switches and DNA repair ... 00:20:00 Importance of pineal and thymus peptides in protocols ... 00:22:28 Advances in peptide testing and lab beta-testing ... 00:28:05 Clinical outcomes: organ regeneration and normalized function ...00:35:54 Bioregulator peptides vs. synthetics: modulation vs. boosting ... 00:39:28 Dr. Lawrence's personal telomere and epigenetic age results ... 01:07:56 Impact of stress and meditation on telomere length ... 01:10:37 Group results: significant telomere and epigenetic age reversal ... 01:13:03 System-level organ age tracking and protocol targeting ... 01:27:14 International expansion and next steps in peptide research ... 01:37:03   Our Amazing Sponsors:   Kineon - near-infrared light helps improve circulation, oxygen delivery, and mitochondrial function, which can support focus, recovery, and even overall brain health. Visit kineon.io/NATNIDDAM and get 10% off!   BEAM Minerals - Mineral deficiency support. One shot in the morning, tastes like water, and you've just restored every essential mineral your cells are craving. Go to beamminerals.com, use code NAT20, and get 20% off your first order.   Nootropept by LVLUP - an advanced cognitive enhancement formula that combines fast-acting neuropeptides, cholinergic support, and mitochondrial-boosting compounds to sharpen mental clarity, memory, and long-term brain performance. Visit https://lvluphealth.com/ and use code NAT at checkout for 20% off.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined by the incomparable Dr. Ted Achacoso—a true pioneer in shifting healthcare from "what's wrong with you" to "what's right with you." Trained across neurology, pharmacology, AI, and nutritional medicine, Dr. Achacoso brings a sharp mix of science, humor, and unfiltered honesty to our conversation. We get real about what it takes to optimize health at the cellular level, why metabolomics is the future doctors can't ignore, and how something as simple as a toxicity panel can completely change your health trajectory.   Episode Timestamps: Welcome and episode introduction ... 00:00:00 Science, laughter, and Dr. Ted's background ... 00:00:38 Early curiosity, accelerated medical pathway ... 00:07:20 Reframing healthcare: from disease to wellness ... 00:14:04 Cell danger response and importance of metabolomics ...00:16:15 Case study: toxicity panel as diagnostic game-changer ... 00:35:17 Patient motivation and behavioral change ... 00:44:20 Vitamin D: its underestimated power and role ... 00:51:12 Vitamin D paradox, genetics, and medication effects ... 01:00:34 Daily longevity habits and mindset ... 01:22:03 Longevity in one word: balance ... 01:33:05 Home Hope resources and closing ... 01:35:20   Our Amazing Sponsors:   Tro Mune by Troscriptions - Cold season doesn't have to take you out. I use Tro Mune—a nightly buccal troche with 75 mg cordycepin—to build immune resilience while I sleep. Take ½–1 before bed, and use it before you get sick or right when you feel it. Troscriptions.com, use NAT10, and get 10% off your first order.   Digestive Bitters by Just Thrive - One capsule before eating helps your body absorb more nutrients, ease digestion, and leave you feeling light instead of weighed down. Head over to Justthrivehealth.com/discount/NAT and use code NAT20 for 20% off.   Tranq Dart by Wizard Sciences - a multi-pathway sleep support from Wizard Sciences. It's not a knockout pill; it's a gentle nudge toward that wind-down zone. I take it about 30 minutes before bed, and it helps my body and brain sync up for sleep. Visit wizardsciences.com and use code NAT15 for 15% off. Sleep smarter, not harder.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined by the innovative Jon Hacker, whose name couldn't be more perfect for the biohacking space. While his family hacks computers, Jon decided to hack something a bit messier—the human mind. After growing up with severe OCD and witnessing the rising tide of global anxiety, he became obsessed with one question: Why are we all stuck in fight or flight, and what can we actually do about it?   Use code NAT at https://zenbud.health/nat for 15% off   Episode Timestamps: Introduction to Longevity Podcast and Host ... 00:00:00 The Rise of Anxiety and Mental Health Innovation ... 00:05:19 Why Modern Society Fuels Anxiety ... 00:07:18 Impact of Chronic Stress on Health ... 00:08:51 Barriers to Managing Anxiety with Habits Alone ... 00:17:17 CBT and the Need for Better Tools ... 00:19:27 Vagus Nerve: What It Does and Why It Matters ... 00:20:37 Zenbud: Ultrasound vs. Electrical Stimulation ... 00:28:58 Zenbud Headset Experience and Simplicity ... 00:34:25 Zenbud's Role in Stress Resilience and Longevity ... 00:47:45 Purpose, Mindfulness, and the Future of Biohacking ... 00:50:55 Zenbud: Key Safety Points and Adoption Challenges ... 01:01:08 Zenbud as "An Off Switch for Stress" and Closing ... 01:02:52 Final Tips, Special Offer, and Outro ... 01:03:30   Our Amazing Sponsors: Sunlamp (BTS2) by Mitolux - When your skin makes vitamin D from UVB light, it also creates natural companion molecules that help your body use it smarter—so you're not just boosting levels, you're activating your biology the way nature intended. Visit mitolux.com/NAT10. You'll receive 10% off! NAT10 will be automatically applied at checkout.   NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It's about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you'd get from a glass of pomegranate juice. Visit Timeline.com/nat20 and use code nat20 for 20% off your purchase.   Probiotic Breakthrough by Bioptimizers - uses a stress-tested Lactobacillus plantarum strain that showed over 30× greater survival in bile and intestinal fluid vs. generic strains. Save 15% at bioptimizers.com/bionat and use code BIONAT for 15% off any order.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Today, I'm joined by the incredible Nadine Artemis, a true pioneer in natural beauty and holistic health. Nadine is well known for bridging the gap between ancient wisdom and modern science, and in this episode, she completely redefines how we look at hair care—not just as a cosmetic routine, but as a form of biological reset. She shares how everything from stress to toxins and even your shower water can disrupt the delicate ecosystem of your scalp, and how her simple, nature-inspired rituals can help restore balance.   Past episode: Episode #90: Do You Want Less Trips To The Dentist, Whiter Teeth, And Better Overall Health? Episode #103: Safe Sunscreen, Circadian Rhythm, and Do We Actually Age with Sun?   Study with Rosemary: https://pubmed.ncbi.nlm.nih.gov/25842469/ Scalp applicator   Episode Timestamps: Episode introduction and focus on hair health ... 00:00:00 Meet Nadine Artemis and "Renegade Beauty" ... 00:04:05 Hair and oral health as longevity signals ... 00:09:33 Skin/scalp microbiome and product residues ... 00:12:01\ Stress, hormones, and pandemic hair loss ... 00:14:14 Optimizing hair follicle growth and supplements ... 00:15:43 Scalp cleansing, massaging, and circulation ... 00:21:25 Filtering water and natural scalp treatments ... 00:26:08 Rosemary oil, melatonin for hair regrowth ... 00:32:15 Photobiomodulation and red light for scalp ... 00:36:30 Essential oils—antimicrobial, support for dandruff ... 00:51:09 Practical routines for dry/flaky vs. oily scalp ... 01:05:49 Navigating hormonal and age-related hair changes ... 01:07:07 Summary of effective natural hair care strategies ... 01:16:00   Our Amazing Sponsors: Kineon: near-infrared light helps improve circulation, oxygen delivery, and mitochondrial function, which can support focus, recovery, and even overall brain health. Visit kineon.io/NATNIDDAM and get 10% off!   Fatty15: C15 is 3x more effective than omega-3 and totally vegan. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/NATNIDDAM and using code NATNIDDAM at checkout.   Manukora honey - From remote forests in New Zealand, where bees collect nectar from the native Manuka tea tree. That nectar is naturally rich in antibacterial compounds like MGO, plus antioxidants and prebiotics that support immunity and gut health. Visit manukora.com/NAT to save up to 31% plus $25 worth of free gifts with the Starter Kit - you'll get an MGO 850+ Manuka Honey jar, 5 travel sticks, a wooden spoon, and a guidebook.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group