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Parkinson Weekly

Author: Oruen CNS

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Parkinson Weekly is your go-to podcast for the latest insights in Parkinson’s disease. Each week, Professor Bas Bloem, Consultant Neurologist in the Department of Neurology at Radboud University Medical Center, Nijmegen, takes you through his chosen “Article of the Week” – highlighting new research, clinical perspectives, and what it means for patients, carers, and healthcare professionals.

Have a question you’d like Bas to answer on the podcast? Email us at parkinsonweekly@gmail.com – we’d love to hear from you.

Stay informed, stay connected, and join us every week for clear, expert-led discussions on Parkinson’s.

24 Episodes
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🎙️ We’re back with the twentieth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this episode, Bas discusses Exploring the impact of Parkinson’s disease on driving: a population-based survey, a large real-world study examining how Parkinson’s affects driving ability, licence retention, and conversations between patients and healthcare professionals. Driving is closely tied to independence, identity, and quality of life — yet both motor and non-motor symptoms of Parkinson’s can comp...
🎙️ We’re back with the nineteenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this episode, Bas shines a light on an often overlooked aspect of Parkinson’s disease: cognitive challenges and the practical “detours” people use to navigate them in daily life. He pays tribute to the late Marina Noordegraaf — artist, advocate, and person with Parkinson’s — whose pioneering work helped make these invisible thinking obstacles visible. Building on her earlier work around motor “detours...
🎙️ We’re back with the eighteenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this episode, Bas discusses new evidence on an old drug: amantadine. He reviews the PREMANDYSK study, a large multicentre, randomised, placebo-controlled trial conducted across 15 specialist centres in France and published in Movement Disorders, which investigated whether early use of amantadine can delay or prevent the development of levodopa-induced dyskinesias in people with Parkinson’s disease. Ba...
🎙️ We zijn terug met de zeventiende aflevering van Parkinson Weekly, gepresenteerd door prof. Bas Bloem. Bas bespreekt het Artikel van de Week: Incidence and Spatial Variation of Parkinson’s Disease in the Netherlands in 2017–2022, gepubliceerd in The Lancet Regional Health – Europe. Hij licht de innovatieve methodologie van het onderzoek toe, waarbij meerdere nationale databronnen zijn gebruikt om nieuwe gevallen van de ziekte van Parkinson in Nederland in kaart te brengen. Daarnaast belicht...
🎙️ We’re back with the seventeenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. Bas discusses the Article of the Week: Incidence and Spatial Variation of Parkinson’s Disease in the Netherlands in 2017–2022, published in The Lancet Regional Health – Europe. He breaks down the study’s innovative methodology, which used multiple national data sources to map new Parkinson’s cases across the Netherlands, and highlights the key findings, including stable incidence over the study period, ...
🎙️ We’re back with the sixteenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this episode, Bas discusses the Article of the Week: Mucuna pruriens in untreated Parkinson’s disease in sub-Saharan Africa: A 12-month, multicenter, randomized, controlled trial. He explores the study’s design, key findings, and what this important research tells us about alternative, accessible treatment options for Parkinson’s disease, particularly in under-resourced settings, as well as its broader...
🎄🎙️ We’re back with a special Christmas bonus episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this festive episode, Bas reflects on the many developments, conversations, and lessons from 2025, offering a thoughtful and wide-ranging look at where Parkinson’s disease research and care stand today. From scientific progress and clinical practice to people, policy, and purpose, he shares his perspective on what has changed — and what still needs to evolve. Bas also looks ahead to the fu...
🎙️ We’re back with the fifteenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this week’s episode, Bas explores the next generation of neuromodulation with a focus on Adaptive Deep Brain Stimulation (aDBS), joined by special guest Dr. Martijn Beudel. Together, they unpack how aDBS moves beyond traditional continuous stimulation by dynamically responding to a patient’s brain signals in real time. The discussion highlights the potential of this personalised approach to improve sym...
🎙️ We’re back with the fourteenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this week’s episode, Bas delves into the rapidly evolving world of artificial intelligence and its growing influence on Parkinson’s disease care and healthcare in general. He explores how AI-driven tools offer remarkable new possibilities — from earlier diagnosis to personalised treatment strategies — while also highlighting the ethical, clinical, and practical concerns that come with relying on algor...
🎙️ We’re back with the thirteenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this week’s episode, Bas explores the powerful intersection between art and Parkinson’s disease — how creativity, expression, and the artistic process can offer unique insights into living with the condition. From movement and emotion to identity and resilience, Bas reflects on the ways art can illuminate aspects of Parkinson’s that clinical measures often overlook. The article of the week, “Shades of...
🎙️ We’re back with the twelfth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this week’s episode, Bas examines whether today’s clinical study assessments are truly prepared for the future of Parkinson’s research and care. With rapid advances in technology, emerging biomarkers, and new digital tools, long-established rating scales and outcome measures are increasingly being questioned. Do they genuinely reflect what matters most to people living with Parkinson’s? And how might cl...
🎙️ We’re back with the eleventh episode of Parkinson Weekly, hosted by Prof. Bas Bloem. This week’s Article of the Week delves into the emerging role of faecal microbiota transplantation (FMT) as a potential treatment for Parkinson’s disease. Building on growing evidence linking gut health and neurological function, the study examines whether restoring a healthy gut microbiome could help alleviate symptoms and possibly influence disease progression. 👉 You can read the full article below: http...
🎙️We’re back with the tenth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. This week’s Article of the Week explores an exciting and rapidly evolving field of research — the potential for lifestyle interventions to not only alleviate symptoms but also influence the underlying disease process in Parkinson’s. From exercise and diet to sleep and stress management, the discussion sheds light on how small, evidence-based lifestyle changes can make a meaningful difference in patients’ lives...
🎙️ We’re back with the ninth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. In this special episode, Professor Bas Bloem shares his top book recommendations on Parkinson’s disease — a hand-picked selection of titles that offer insight, inspiration, and understanding for anyone affected by or interested in the condition. From personal stories and patient perspectives to the latest scientific research and clinical wisdom, Bas introduces each book with a brief description of why it stan...
🎙️ We’re back with the eighth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. This week’s Article of the Week highlights a fascinating and innovative area of research: In this episode, Professor Bas Bloem reviews the study 'Association of ultra-processed food consumption with prodromal, incident Parkinson's disease and mortality'. Tune in as he discusses how dietary choices might influence the risk and progression of Parkinson’s disease. 👉 You can read the full article below: https://...
🎙️ We’re back with the seventh episode of Parkinson Weekly, hosted by Prof. Bas Bloem. This week’s Article of the Week highlights a fascinating and innovative area of research: In this episode, Professor Bas Bloem reviews the study "Beyond MIND and Mediterranean Diets: Designing a Diet to Optimize Parkinson's Disease Outcomes" Tune in as he discusses how nutrition could play a pivotal role in shaping better outcomes for people living with Parkinson’s. 👉 You can read the full article below: ht...
🎙️ We’re back with the sixth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. This week’s Article of the Week highlights a fascinating and innovative area of research: In this episode, Professor Bas Bloem reviews the study “Hypoxic Conditioning in Parkinson’s Disease: Randomized Controlled Multiple N-of-1 Trials.” He explores how controlled exposure to hypoxia may offer therapeutic potential in Parkinson’s disease, discussing the study design, key outcomes, and what this could mean for...
🎙️ We’re back with the fifth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. This week’s Article of the Week explores an exciting area of research: In this episode, Professor Bas Bloem reviews two groundbreaking studies marking a major step forward in regenerative medicine for Parkinson’s disease: a Phase I trial of hES cell-derived dopaminergic neurons and a Phase I/II trial of iPS-cell-derived dopaminergic cells. He discusses the scientific progress, safety outcomes, and the potenti...
🎙️ We’re back with the fourth episode of Parkinson Weekly, hosted by Prof. Bas Bloem. This week’s Article of the Week explores an exciting area of research: Bas explores the intriguing connection between proximity to golf courses and the risk of Parkinson’s disease. Join us as we discuss the findings of the latest research article and what it could mean for understanding environmental factors linked to Parkinson’s. 👉 You can read the full article here: https://pubmed.ncbi.nlm.nih.gov/40338549...
🎙️ We’re back with a BONUS episode of Parkinson Weekly, hosted by Prof. Bas Bloem. We’re thrilled to bring you a very special bonus episode featuring The Parkinson’s Plan, recently recognised as a New York Times Best Seller! 📚✨ In this episode, we dive into the insights and strategies from the book that are helping people with Parkinson’s take control of their health, lifestyle, and daily routines. Whether you’re living with Parkinson’s, supporting someone who is, or simply passionate about n...
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