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Simply Oncology

Author: John McGrane & Michael Rowe

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Welcome to Simply Oncology. 
Cancer is daunting for both patients and for clinical teams.
Dr John McGrane and Dr Michael Rowe are oncologists who want to break down the complex parts of cancer care into clear and simple sessions.
We will dive deep into the world of cancer research, patient stories and the latest cancer breakthroughs. 
Simply Oncology will have patient focused episodes along with episodes that allow anyone with an interest in oncology to stay up to date.

We hope you join us as we unpick all parts of cancer. 

John & Mike

98 Episodes
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Send us Fan Mail Join us for something a bit different this week!! We though it would be fun ( and hopefully helpful) to make an A to Z of Oncology. Are you a patient or care who is newly diagnosed with cancer. Are you new to working around cancer care. Are you in training and want to learn more. Indeed- are you in cancer care and want to know why we have chosen our A to Z. We get the super experienced Clinical Nurse Specialist Debbie Victor to help us out. As Education trustee for the Britis...
Send us Fan Mail Join us as we tackle the topic of Artificial intelligence in Radiotherapy. This week we speak to the excellent Professor Ajay Aggarwal about the use of AI in radiotherapy planning. We discuss the international ARCHERY trial using an AI radiotherapy planning tool to streamline radiotherapy planning in prostate, head & neck and cervical cancers. This PRA artificial planning tool developed at the MD Anderson hospital could unlock huge radiotherapy delivery potent...
Send us Fan Mail 🎙️New Simply Oncology Podcast to complete our PSMA Lutetium in #ProstateCancer 🎙️Join us for the Part 2 of our masterclass with the superb Dr Amy Eccles⭐️ As we focus on #ProstateCancerAwarenessMonth we look at future directions for PSMA Lutetium in Prostate Cancer. The British Nuclear Medicine Society are having there annual conference this week. Molecular radiation may offer amazing treatment options in the near future🙌🏽 See link below👇or wherever you get yo...
Send us Fan Mail PSMA Lutetium has been in the background for metastatic prostate cancer for several years. Joins us as we discuss this exciting treatment in metastatic prostate cancer with the excellent Dr Amy Eccles who works at Imperial Hospital London and also the London Clinic. Amy is a radiologist who delivers PSMA Lutetium at the London Clinic and shares her experience with us. Attaching Lutetium-177 to PSMA to deliver a beta-emitting radiation payload to prostate cancer cells. Essenti...
Send us Fan Mail Late effects after pelvic radiotherapy part 2. Join us as we complete our conversation with the wonderful Macmillan Late effects consultant radiographer Lisa Durrant. Last week we discussed late bladder and bowel effects from radiotherapy. In this weeks episode we discuss; - hyperbaric oxygen therapy - pelvic floor exercises - pain as a late effect of radiotherapy - sexual function issues post radiotherapy Lisa gives us some great practical tips on how to support patien...
Send us Fan Mail Join us as we discuss the impact of Pelvic Radiation Disease & the late effects of radiotherapy in the pelvis. We re always trying to get he best result for our patients and to cure cancer but we need to take time to deal with the impact of radiotherapy side effects in our patients. We are talking radiotherapy for pelvic cancers; bladder, prostate, gynaecological and rectal cancers. Lisa is a consultant radiographer pioneering support for patients with late effects of rad...
Send us Fan Mail Join us as return to our excellent conversation on biomarkers in kidney cancer with the wonderful Professor Laurence Albiges from Paris. 🎙️We finish our overview of Biomarkers in metastatic Kidney Cancer with the superb Professor Laurence Albiges from the Gustave Roussy Hospital in Paris 🇫🇷 Which biomarker will help us to decide which treatment to select in metastatic #KidneyCancer - IOIO vs IOTKi - when to start therapy - monitoring on treatment An exciting spa...
Send us Fan Mail Join us for a special Kidney Cancer treat!!! A Must Listen episode!! We discuss the role of biomarkers in advanced kidney cancer with the wonderful Professor Laurence Albiges from the Gustave Roussy Institute of Oncology in Paris. No Kidney Cancer talk is complete without the question -" Where are we with biomarkers?" This is part 1 of a 2 part walkthrough of the biomarker story so far in kidney cancer. Laurence is unequalled in her clear delivery on this subject. As lead for...
Send us Fan Mail Join us as we return to complete our run through the landscape of metastatic renal cancer with the effervescent Professor Ricky Frazer. We look at the Dolly Mixture of subtypes that makes up non clear cell renal carcinoma. We discuss the new HIF2a inhibitors such as belzutifan. We look at future directions in kidney cancer. A treat for anyone who treats kidney cancer. Enjoy!
Send us Fan Mail Join us is as we celebrate Kidney Cancer week with a Masterclass walk through metastatic Renal Cancer with Professor Ricky Frazer from Velindre Cancer Centre. Ricky is a co-host of the hugely successful Immunobuddies podcast and has a vast experience in immunotherapy management. We look at the indications for immunotherapy versus anti-VEGF TKI therapy. Should we just accept anti-VEGF TKI monotherapy in Favourable Risk patients? When should we try IO/IO combination versus IO/T...
Send us Fan Mail Join us for Part 2 of our Metastatic Endometrial Cancer special with the amazing Dr Gemma Eminowicz from University College London Hospital. In episode 1 we looked at molecular profiling and immunotherapy. In this episode we explore the role of; - hormone therapy - Antibody drug conjugates - PARP inhibitors Endometrial cancer is taking off in terms of new and exciting treatment options. Gemma does an amazing job talking us through them. Enjoy.
Send us Fan Mail Dr Gemma Eminowicz returns for 2026!! Join us as we discuss the metastatic endometrial cancer landscape with Simply Oncology 'friend of the show' Dr Gemma Eminowicz from University College Hospital London. Advanced endometrial cancer is so much more than carboplatin and paclitaxel. It now has the complete range of oncological treatments; - Chemotherapy - Immunotherapy - Antibody Drug Conjugates - Hormone therapy - Targeted therapy - Radiotherapy We look at how the molecular t...
Send us Fan Mail We return for part 2 of our overview on metastatic oesphago-gastric cancer. Join us as we welcome back Dr Lizzy Smyth from Oxford University Hospitals. We look at the importance of nutritional support. We discuss future directions such as CAR-T therapy Lizzy mocks John (again!!) A brilliant finish to our OG masterclass from Lizzy. Enjoy!
Send us Fan Mail Dr Lizzie Smith from Oxford University Hospitals gives us a an amazing 2 part overview of management of metastatic Oesophago-Gastric cancer. We discuss molecular testing and therapy options in metastatic OG cancer🧬 HER2 PDL 1 Claudin 18.2 Lizzy is a hugely respected figure in OG cancer and key clinical trialist! John gets put in his place by Lizzy on several occasions!! Lizzy has a way of describing things that even John could understand!! Part 1 of 2 in this metastatic O...
Send us Fan Mail Happy New Year!!! WE return in 2026 to complete our overview of PARPi in prostate cancer with the peerless Professor Rob Jones.
Send us Fan Mail Join us as we unwind in the Christmas Holiday period with a masterful overview of PARP inhibitors in metastatic prostate cancer with Professor Rob Jones. Rob is an old friend of the show and is amazing at setting the scene for who & when PARP inhibitors can be useful in metastatic prostate cancer.
Send us Fan Mail Welcome back! In part 1 we discussed the major effects of menopause and how these can be worsened by hormonal medications given to treat breast cancer and the impact these can have on patients completing treatment as planned. In this episode we welcome back Dr Rebecca Bowen and discuss practical advice on managing these symptoms including a link to what will be a vital resource for all clinicians in Oncology and Primary Care: the Meno.Pause app. Link below, download today! ...
Send us Fan Mail When is it safe to giving HRT in women who are being treated or have previously been diagnosed with breast cancer? Will the use of vaginal oestrogens affect breast cancer outcomes? What is the trade off on quality of life when symptoms of the menopause aren't managed? Did you know that roughly 1 in 4 women stop their hormone therapy for breast cancer due to menopausal side effects!! Who better to answer these questions and more than Dr Rebecca Bowen, Consultant Oncologist in ...
Send us Fan Mail Sexual health in cancer is a topic we need to talk more about. So many patients feel unable to discuss their sexual health and also clinical teams don’t also mange to bring the topic up. A cancer diagnosis can affect self image and confidence. We talk to Lorraine Grover who is a sexual health specialist nurse about how we can break down some of these barriers. Erectile dysfunction and much more discussed. You may never look at a Calypo ice lolly the same again !! This e...
Send us Fan Mail We return to Part 2 of our walk through metastatic bowel cancer with the excellent Professor Naureen Starling. We look at RAS, BRAF and future directions for treatment of metastatic bowel cancer. Can ctDNA have a role in metastatic bowel cancer? What role may HER2 have to play going forward? What is exciting on the horizon in mCRC? Enjoy!!
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