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The latest health care news you need, when you need it. Only at Healio.
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In this edition, we look at rehabilitation protocols, how AI can help patients with total knee arthroplasty, synthetic THC and more. Read the full coverage here: 'Quiet knee' rehabilitation protocol may reduce opioid exposure after TKA AI-enabled decision aid may improve TKA decision-making Synthetic THC may not reduce opioid intake after TKA Lorecivivint yields 'meaningful' improvements in knee osteoarthritis at 1 year Corticosteroid injections yield 'disappointing' response in knee osteoarthritis References: Baker J. Abstract 2624. Presented at: ACR Convergence 2025; Oct 24-29, 2025; Chicago. Bhatti P, et al. Poster 30. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas. Jayakumar P, et al. Paper 30. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas. Jennings JM, et al. Paper 10. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas. Yazici Y. Abstract 2626. Presented at: ACR Convergence 2025; Oct 24-29, 2025; Chicago.
In this edition, FDA warns complications following radiofrequency microneedling device use, chronic hand eczema considered "common" disease, and more. Read the full coverage here: Q&A: FDA warns of radiofrequency microneedling risks; here's what to know Chronic hand eczema now considered a 'common' skin disease in US 'Unproven' topical estrogens for the face may bring some risks FDA approves Restylane Lyft to treat receding chin References Chovatiya R, et al. Prevalence of self-reported physician diagnosis of chronic hand eczema in adults: A cross-sectional study of more than 10,000 participants in the general population – Results from the CHECK study in the United States. Presented at: Fall Clinical Dermatology Conference; Oct. 23-26, 2025; Las Vegas. Farkas E, et al J Am Acad Dermatol. 2025;doi:10.1016/j.jaad.2025.08.050. Healio Interviews Press Release
In this edition, Congress reintroduces the Safe Step Act, an expert expresses doubt about the benefits of TrumpRx and more. Read the full coverage here: Congress reintroduces Safe Step Act to amend step therapy policies Q&A: TrumpRx, Pfizer deal sidestep health insurance companies Complete hair regrowth for some with alopecia after 3-year ritlecitinib treatment Waterproof bandages 'reasonable alternative' to petroleum-based wound care References · Bell MC, et al JAMA Dermatol. 2026;doi:10.1001/jamadermatol.2025.4051. · Healio Interviews · King B, et al. Abstract #LBA-335. Presented at: European Academy of Dermatology and Venereology Congress; Sept. 17-20, 2025; Paris.
In this edition, we look at the impact of GLP-1s on total joint replacement, the safety of NSAID's and more. Read the full coverage here: GLP-1s may have profound impact on total joint replacement NSAID use may be safe prior to total joint arthroplasty Complication risk may be lower for revision TJA when performed in ASC Despite improved function, patients with elbow dislocation often report long-term pain Osteochondral allograft transplant may treat pediatric elbow osteochondritis dissecans References: Acuña AJ, et al. Paper 33. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas. Foran JRH, et al. Paper 31. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas. Healio Interviews Perkins CA, et al. Am J Sports Med. 2025;doi:10.1177/03635465251366903. Plaisier N, et al. Paper 29. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix.
In this edition, immunotherapy in advanced lung cancer, updates in EGFR-mutated lung cancer and more. Read the full coverage here: VIDEO: Immunotherapy in advanced lung cancer among highlights from ESMO 2025 VIDEO: Updates in EGFR-mutated lung cancer from ESMO 2025 VIDEO: DeLLphi-303 results show 'major jump in survival' for SCLC patients Emphysema found during lung cancer screening raises risk for mortality Q&A: More nonsmokers developing lung cancer due to radon exposure, air pollution References · González Gutiérrez J, et al. Radiology. 2025;doi:10.1148/radiol.250949. · Healio Interviews · Healio Interviews · Healio Interviews · Paulson KG, et al. Abstract OA13.01. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona.
In this edition, we look at robotic-assisted surgery, dislocation risk in fixed-bearing THA and more. Read the full coverage here: Higher head-to-cup ratio, robotic-assisted surgery may lower dislocation rate after THA Fully maximizing bearing diameter may reduce dislocation risk in fixed-bearing THA How may GLP-1s impact nutrition prior to orthopedic surgery? Medicare contractors propose coverage restriction of peripheral nerve block procedures Physician content on TikTok may guide patient education References: Expert submission Healio Interviews Healio Interviews Kobayashi JK, et al. Paper 54. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas. Wang E, et al. Maximizing bearing diameter markedly lowers dislocations in primary total hip arthroplasty. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.
In this edition, increased lung cancer screening improving outcomes, overall survival data from FLAURA2 trial and more. Read the full coverage here: Increased lung cancer screening improving outcomes, but rates 'still too low' VIDEO: Overall survival data from FLAURA2 trial presented at WCLC Updated NCCN guidelines on NSCLC put spotlight on biomarker testing 'Never too late': Smoking cessation after cancer diagnosis can extend survival New treatments worsened income-based survival disparities for lung cancer, melanoma References · American Lung Association 2025 State of Lung Cancer. · Khor S, et al. JCO Oncol Adv. 2025;doi:10.1200/OA-25-00026. · National Comprehensive Cancer Network. · Planchard D, et al. Abstract PL02.06. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona. · Tohmasi S, et al. J Natl Compr Canc Netw. 2025;doi:10.6004/jnccn.2025.7059.
In this edition, we look at the first FDA approval of an oral therapy for chronic spontaneous urticaria, and more. Read the full coverage here: FDA approves first oral therapy for chronic spontaneous urticaria Denifanstat safe, effective in acne vulgaris treatment FDA approves Zoryve cream 0.05% for pediatric atopic dermatitis The 'Zoom boom' effect: Post-pandemic cost concerns for facial cosmetic procedures References: F Xiang, et al. Abstract #LBA-213. Presented at: European Academy of Dermatology and Venereology Congress; Sept. 17-20, 2025; Paris. Pecora V, et al. J Drugs Dermatol. 2025;doi:10.36849/JDD.9102. Press Release Press Release
In this edition, we look at how AI can help patients with total joint arthroplasty, the impact of opioid use on in-hospital sleep and more. Read the full coverage here: Custom-tailored AI platform may be feasible for addressing patient questions before TJA Opioid use may negatively affect in-hospital sleep, orthopedic trauma outcomes Polymicrobial infection may predict septic long bone nonunion repair reoperation Patients recognize importance of nutrition after surgery, need help with implementation GLP-1s may offer a 'protective effect' in shoulder surgery for patients with diabetes References: Barth K, et al. Paper 63. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix. Martiono JA, et al. Paper 1. Presented at: American Shoulder and Elbow Surgeons Annual Meeting; Oct. 15-18, 2025; San Diego. Rizk AA, et al. Paper 4. Presented at: American Shoulder and Elbow Surgeons Annual Meeting; Oct. 15-18, 2025; San Diego. Schenker ML, et al. Paper 65. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix. Zepeda KE, et al. Poster 13. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct. 23-26, 2025; Dallas.
In this edition we look at hip fracture surgery delays, how homelessness affects hip surgery outcomes and more. Read the full coverage here: Hip fracture surgery delay may increase mortality risk Homelessness may be a predictor of poor outcomes following hip fracture surgery Biological age, age acceleration may predict 1-year mortality after geriatric hip fracture Hip resurfacing device had low all-cause revision rate at 8-year follow-up Group cycling program leads to 'meaningful benefit' in hip osteoarthritis References: Cobb JP. Paper 11. Presented at: American Association of Hip and Knee Surgeons Annual Meeting; Oct 23-26, 2025; Dallas. Healio interviews Hoveidaei AH, et al. Paper 7. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix. King SW, et al. Hip fracture surgery delayed by operating room capacity is an independent risk factor for 120-day mortality. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix. Randall Z, et al. Paper 2. Presented at: Orthopaedic Trauma Association Annual Meeting; Oct. 15-18, 2025; Phoenix.
In this edition, FDA approves golimumab for pediatric ulcerative colitis, hospital affiliation linked to higher-cost care and more. Read the full coverage here: FDA approves golimumab for pediatric ulcerative colitis 'Tremendous implications': Hospital affiliation linked to higher-cost care 'Set a 2-TikTok limit': Smartphone use on toilet linked to higher risk for hemorrhoids APPs step up to fill GI care gaps, but scant on-the-job training fuels own burnout Rideshare 'potentially scalable intervention' to improve colonoscopy after abnormal FIT References: Expert Submission Issaka RB, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.30515. Kapoor DA et al. J Mark Access Health Policy. 2025;doi:10.3390/jmahp13030036. Press Release Ramprasad C, et al. PLoS One. 2025;doi:10.1371/journal.pone.0329983.
In this edition, radiation is a 'strong alternative' for surgery, FDA approves combination therapy for small cell lung cancer and more. Read the full coverage here: Radiation a 'strong alternative' to surgery for early-stage lung cancer FDA approves lurbinectedin, atezolizumab combination for small cell lung cancer Diagnostic yield high with robotic-assisted bronchoscopy in peripheral lung lesions Machine learning model predicts urgent care visits during lung cancer treatment Evidence is 'clear': Medicaid expansion significantly improves long-term cancer survival References: Gonzalez BD, et al. JCO Clin Cancer Inform. 2025;doi:10.1200/CCI-24-00315. Kleber T, et al. Abstract 268. Presented at: ASTRO Annual Meeting; Sept. 27-Oct. 1, 2025; San Francisco. Press Release Schafer EJ, et al. Cancer Discov. 2025;doi:10.1158/2159-8290.CD-25-1244. Steinack C, et al. OA1178: Robotic-assisted bronchoscopy with integrated cone-beam CT vs. conventional bronchoscopy for diagnosing peripheral pulmonary lesions: An open-label randomized controlled trial. Presented at: European Respiratory Society International Congress; Sept. 27-Oct. 1, 2025; Amsterdam.
In this edition, bioinductive implants for ACL reconstruction, osteochondral defects treatments and more. Read the full coverage here: ACL reconstruction with reinforced bioinductive implant may yield favorable outcomes Multiplug, single-plug techniques had comparable outcomes for osteochondral defects MRI-based clinical prediction model identified risk factors for patellar instability New technology, cost strategies continue to move robotic-assisted surgery forward Physician referral to physical therapy underutilized for patients with knee osteoarthritis References: Healio Interviews Khoja SS, et al. Arthritis Care Res. 2025;doi:10.1002/acr.25630. McMillan S, et al. Surg Technol Int. 2025;doi:10.52198/25.STI.45.OS1888. Mufti YN, et al. Am J Sports Med. 2025;doi:10.1177/03635465251352172. Nukala V, et al. Arthrosc Sports Med Rehabil. 2025;doi:10.1016/j.asmr.2025.101159.
In this edition, we look at AI bias, nonsurgical biologic therapies and more. Read the full coverage here: 'Math, not magic': Identify and combat bias in AI Orthobiologics: Commit to evidence-based practice, foster cautious optimism TJR indications expand, making it a young man's game Successful management of PJI occurred in about 50% of patients Risks of anteromedial tibial tubercle transfer are minimal and the benefits great References: Expert Submission Healio Interviews Higuera Rueda C, et al. Paper 1409. Presented at: Musculoskeletal Infection Society Annual Meeting; Aug. 1-2, 2025; Jersey City, N.J. Engagement Time: 18 minutes
In this edition, FDA approves subcutaneous chemotherapy for solid tumors, improvements to shared decision-making and more. Read the full coverage here: FDA approves Hernexeos as first oral therapy for NSCLC with HER2 mutations Communication, knowledge critical to improve shared decision-making for lung cancer Detection of ctDNA could help determine use of immunotherapy for small cell lung cancer Subcutaneous amivantamab plus lazertinib produces similar results to IV regimen in NSCLC Lung cancer screening guidance needed for certain never-smokers References: Bi N, et al. Abstract 2034. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona. Press Release Scott SC, et al. Abstract 1798. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona. Shum E, et al. Abstract 2172. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona. Villalon D, et al. Abstract 2368. Presented at IASLC World Conference on Lung Cancer; Sept. 6-9, 2025; Barcelona.
In this edition, ultra-processed grains linked to elevated risk for IBD, CTA use for GI bleeds increase and more. Read the full coverage here: Ultra-processed grains linked to elevated risk for IBD, especially ulcerative colitis 'Double whammy:' CTA use for GI bleeds rise, but diagnostic yield drops 'Another layer of benefit': GLP-1s linked to lower risk for peptic ulcer disease 'Simplified care models' needed for chronic HBV care to meet 2030 global elimination goals 'Stay vigilant': Routine exposure to AI may reduce ADR in standard colonoscopy References: Budzyń K, et al. Lancet Gastroenterol Hepatol. 2025;doi:10.1016/S2468-1253 (25) 00133-5. Narula N, et al. Am J Gastro. 2025;doi:10.14309/ajg.0000000000003700. Prasad S, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.29746. Seika P, et al. Clin Gastroenterol Hepatol. 2025;doi:10.1016/j.cgh.2025.08.015. Stockdale AJ, et al. Lancet Gastroenterol Hepatol. 2025;doi:10.1016/S2468-1253(25)00163-3.
In this edition, we look at labral reconstruction in adolescents, the risk of skipping breakfast on osteoporotic fractures and more. Read the full coverage here: Labral reconstruction yielded favorable outcomes among adolescent patients Skipping breakfast, eating late dinners may raise risk for major osteoporotic fractures AI may personalize patient care, identify surgical risks Surgical fixation for pickleball-related Achilles ruptures may improve quality of life Screening for osteoporosis, preventing fractures essential in diabetes care References: Chen C, et al. Paper 17. Presented at: American Orthopaedic Society for Sports Medicine Annual Meeting; July 10-12, 2025; Nashville, Tenn Domb BG, et al. Paper 50. Presented at: American Orthopaedic Society for Sports Medicine Annual Meeting; July 10-12, 2025; Nashville, Tenn. Kemmis K. Presentation D27. Presented at: ADCES25; Aug. 8-11, 2025; Phoenix. Nakajima H, et al. J Endocr Soc. 2025;doi:10.1210/jendso/bvaf127. Weight C. AI in the OR: Personalizing care, lowering complications and automating surgery. Presented at: Cleveland Clinic's A.I. Summit for Healthcare Professionals; July 11, 2025; Cleveland.
In this edition, we look at the risk orthopedic surgeons face from insufficient malpractice coverage, the role of AI in osteoporosis and more. Read the full coverage here: AI-assisted diagnostic system may identify osteopenia, osteoporosis Insufficient malpractice coverage may place surgeons caring for elite athletes at risk Psychological readiness, stress improved 2 years after ACL reconstruction Patella resurfacing reduced maltracking, had comparable outcomes as nonresurfacing Patellofemoral osteochondral allograft transplantation may effectively treat lesions References: Jolissaint JE, et al. Paper 1538. Presented at: Musculoskeletal Infection Society Annual Meeting; Aug. 1-2, 2025; Jersey City, N.J. Milewski MD, et al. Paper 57. Presented at: American Orthopaedic Society for Sports Medicine Annual Meeting; July 10-12, 2025; Nashville, Tenn. Moro T, et al. J Orthop Res. 2025;doi:10.1002/jor.70000. Ramkumar PN, et al. Paper 37. Presented at: American Orthopaedic Society for Sports Medicine Annual Meeting; July 10-13, 2025; Nashville, Tenn. Wang T, et al. Paper 28. Presented at: American Orthopaedic Society for Sports Medicine Annual Meeting; July 10-12, 2025; Nashville, Tenn.
In this edition, FDA approves first oral therapy for NSCLC, interstitial lung disease diagnosis raises risk for lung cancer and more. Read the full coverage here: FDA approves Hernexeos as first oral therapy for NSCLC with HER2 mutations ILD diagnosis raises risk for lung cancer Uninsured patients benefit less from immune checkpoint inhibitors than privately insured Shared decision-making visit improves annual lung cancer screening adherence Indoor tobacco, e-cigarette use more common in rural vs. urban homes References: Chung Y, et al. CHEST. 2025;doi:10.1016/j.chest.2025.06.026. Press Release Steinberg AW, et al. Ann Am Thorac Soc. 2025;doi:10.1513/AnnalsATS.202504-419OC. Xu H, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.19630. Zhao J, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.19274.
In this edition, opioid deaths with GI issues tripled in the past decade, prophylactic vancomycin may reduce risk for recurrent C. difficile and more. Read the full coverage here: 'Deeply alarming': Opioid deaths with GI issues tripled in the past decade Prophylactic vancomycin may reduce risk for recurrent C. difficile CRC disparities in Black communities stem from access, not biology, experts say Mediterranean, plant-based diets linked to lower risk for chronic constipation Psychiatric disorders 'common' among patients with inflammatory bowel disease References: Appiah JK, et al. Cureus. 2025;doi:10.7759/cureus.86489. Cadogan K, et al. Crohns Colitis 360. 2025;doi:10.1093/crocol/otaf035. Keating JA, et al. JAMA Netw Open. 2025;doi:10.1001/jamanetworkopen.2025.17834. May FP, et al. Nat Rev Gastroenterol Hepatol. 2025;doi: 10.1038/s41575-025-01087-3. Wang Y, et al. Gastroenterology. 2025;doi:10.1053/j.gastro.2025.06.020.
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