Fertility and Sterility On Air

Welcome to Fertility & Sterility Roundtable! Each week, we will host a discussion with the authors of "Views and Reviews" and "Fertile Battle" articles published in a recent issue of Fertility & Sterility.  This week, we welcome Dr. Paula Amato and Professor Glenn Cohen to discuss the legal and ethical implications of in vitro gametogenesis (IVG) - the creation of human eggs and sperm in a laboratory setting using non-reproductive cells, such as skin or blood cells. Through our discussion, we will explore several issues raised by this nacent technology, including safety, Food and Drug Administration review, embryo destruction, eugenics, enhancement, unauthorized parenthood, inequitable access, and evolving conceptions of parenthood. Dr. Paula Amato is Professor of Obstetrics & Gynecology and Director of the Division of Reproductive Endocrinology & Infertility at Oregon Health & Science University. She received her medical degree from the University of Toronto in Canada, where she also completed her Residency in Obstetrics & Gynecology, followed by a Fellowship in Reproductive Endocrinology & Infertility at the University of California, San Diego. Dr. Amato is past-president of the American Society for Reproductive Medicine. Her research focuses on innovative assisted reproductive technologies for the treatment of infertility and ovarian aging. Professor Glenn Cohen is the James A. Attwood and Leslie Williams Professor of Law at Harvard Law School, where he directs the Center for Health Law Policy, Biotechnology, and Bioethics. A member of the National Academy of Medicine, his work focuses on the intersection of bioethics and the law. He has advised policymakers and global organizations on topics such as genetic privacy, medical AI, and reproductive rights, and his work has been featured by several prominent news outlets, including PBS, NPR, CNN, and The New York Times. View Fertility and Sterility at https://www.fertstert.org/  

In this month's Fertility & Sterility: Unplugged, we take a look at articles from F&S's sister journals! Topics this month include: x (2:41) a link between angiotension II and fibroid development (14:11), use of psychedelics in reproductive medicine (20:27) and an artificial intelligence tool for clinical decision making during stimulation (26:21). F&S Reviews: https://www.fertstertreviews.org/article/S2666-5719(25)00009-X/abstract F&S Science: https://www.fertstertscience.org/article/S2666-335X(25)00091-6/abstract Consider this: https://www.fertstert.org/news-do/psychedelic-medicine-revisited-advances-and-reproductive-health-implications F&S Reports: https://www.fertstertreports.org/article/S2666-3341(25)00017-0/fulltext View the sister journals at: https://www.fertstertreviews.org https://www.fertstertreports.org https://www.fertstertscience.org    

Take a sneak peak at this month's Fertility & Sterility! Articles discussed this month are:   Articles 01:51 Outcomes after frozen embryo transfer failure: changing the protocol does not improve live birth  14:23 Ovarian stimulation with follitropin delta is safe and effective: Results from the RITA randomized, double-blind, placebo-controlled trials  27:52 Donor Identity in Aotearoa New Zealand: a survey of parents regarding disclosure of donor conception to their donor-conceived children 36:55 The association of infertility, miscarriage, stillbirth, and parity with osteoporosis: a pooled analysis of five cohort studies   47:28 Extended Ovarian Transport for Centralized Tissue Cryobanking: Impact on Primordial Follicle Integrity 56:42 Temsirolimus and antimüllerian hormone protect fertility and the ovarian reserve against chemotherapy-induced damage in a murine model 01:04:09 Cost-Effectiveness of Single versus Double Embryo Transfer to Gestational Carriers for Male Same-Sex Intended Parents View Fertility and Sterility Volume 125, Issue 1: https://www.fertstert.org/issue/S0015-0282(25)X0015-7 View Fertility and Sterility at https://www.fertstert.org/  

In this month's Fertility & Sterility: Unplugged, we take a look at articles from F&S's sister journals! Topics this month include: (03:00) prevalence of endometrial hyperplasia and carcinoma among patients with PCOS; differences in trophectoderm gene expression among euploid blasts during extended in vitro culture (13:16), comparison of embryo transfer techniques and pregnancy outcomes (28:58), and exploring the association of ectopic pregnancy with embryonic competence (39:19). F&S Reports: https://www.fertstertreports.org/article/S2666-3341(25)00101-1/fulltext    F&S Science: https://www.fertstertscience.org/article/S2666-335X(25)00067-9/abstract F&S Reviews: https://www.fertstertreviews.org/article/S2666-5719(25)00002-7/fulltext Consider this: https://www.fertstert.org/news-do/beyond-tubal-factors-rethinking-ectopic-pregnancy-through-embryonic-competence-and   View the sister journals at: https://www.fertstertreviews.org https://www.fertstertreports.org https://www.fertstertscience.org    

Fertility & Sterility on Air discusses ASRM INNOVATE, a reproductive health innovation summit that brings together dynamic healthcare professionals, thought leaders, and innovators to forge advancements in reproductive medicine through the synergy of science and technology. Join our host Kate Devine with Jared Robins, Anuja Dokras, and David Sable as they talk about formulating and executing the inaugural ASRM INNOVATE conference dedicated to identifying and addressing gaps and lack of innovation within the field of reproductive medicine by cultivating deliberate collaboration and exchange of ideas between healthcare professionals, innovators, and investors. View Fertility and Sterility at https://www.fertstert.org/  

Fertility & Sterility on Air is at the American Association of Gynecologic Laparoscopists 2025 Global Congress! In this episode, our host Pietro Bortoletto conducts a roundtable with expert reproductive surgeons Rebecca Flyckt, Zaraq Khan, and Michael Neblett on the surgical and medical management of adenomyosis with emphasis on diagnosis, innovative medical therapies, and uterus-sparing surgical techniques designed to optimize fertility outcomes.  View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peek at this month's Fertility and Sterility! Articles discussed this month are:   Articles: 1. The reproductive journey of women with obesity undergoing assisted reproductive technology: an analysis of 48,595 in vitro fertilization cycles in 31,829 women 2.  The reproductive endocrinology and infertility subspecialist: definition, training, and scope of practice in the United States 3. Clinical outcomes in patient-oriented strategies encompassing individualized oocyte number (POSEIDON) low-prognosis patients receiving in vitro fertilization / intracytoplasmic sperm injection treatment: a multi-center retrospective cohort study\ 4. Gonadotropin-releasing hormone antagonist protocol is associated with higher oocyte yield in young women at high risk for low oocyte retrieval: a retrospective study using three statistical methods 5. Outcomes of in vitro fertilization cycles with embryo donation compared with double gamete donation with cryopreserved donor oocytes 6. Leveraging anti-Müllerian hormone and metaphase II oocyte yield to improve counseling for oocyte cryopreservation outcomes 7. Effect of a one-step fast warming protocol on reproductive outcomes of vitrified-warmed blastocysts View the December 2025, Volume 124 Issue 6 of Fertility and Sterility at https://www.fertstert.org/issue/S0015-0282(25)X0013-3 View Fertility and Sterility at https://www.fertstert.org/  

Welcome to Fertility & Sterility Roundtable! Each week, we will host a discussion with the authors of "Views and Reviews" and "Fertile Battle" articles published in a recent issue of Fertility & Sterility.  This week, we welcome Dr. Richard Paulson and Dr. Jamie Kuhlman to discuss Restorative Reproductive Medicine (RRM) — a field that describes itself as focusing on identifying and treating the root causes of infertility rather than bypassing or suppressing natural reproductive processes. In this episode, we explore whether RRM represents a truly novel approach to fertility care, examine its religious and political influences, and consider the potential risks the movement poses to access to evidence-based fertility treatments, including IVF. Dr. Richard Paulson holds the Alia Tutor Chair in Reproductive Medicine and is Professor and vice-chair in the Department of Obstetrics and Gynecology at the University of Southern California, where he is also Director of the Fellowship in Reproductive Endocrinology and Infertility. He is past president of the American Society for Reproductive Medicine, and of the Pacific Coast Reproductive Society. Dr. Paulson has authored over 300 scientific articles and has received more than 35 awards for research and scientific presentations. He is the current Editor-in-Chief of "Fertility & Sterility Reports."  Dr. Kuhlman is a Licensed Psychologist and the Owner of Courageous Path Counseling, PLLC, in Nashville, TN. She specializes in infertility, postpartum, and maternal mental health through individual counseling and psychological evaluations for third-party reproduction. She is also a PRIMED Scholar with the American Society of Reproductive Medicine, focusing on advocacy within reproductive healthcare.  The unscientific nature of the arguments of "Restorative Reproductive Medicine" and why we need to understand them https://www.fertstertreports.org/article/S2666-3341(25)00111-4/fulltext The illusion of reproductive choice: how restorative reproductive medicine violates reproductive autonomy and informed consent https://www.fertstert.org/article/S0015-0282(25)00596-5/fulltext   View Fertility and Sterility at https://www.fertstert.org/  

Fertility & Sterility on Air is at the 2025 ASRM Scientific Congress & Expo in San Antonio, Texas (Part 3)! In this episode, our hosts Pietro Bortoletto, Blake Evans, Eve Feinberg, and Richard Paulson cover: Advancing ICSI robotics: follow up on the transition from remote to fully automated intracytoplasmic sperm injection with Gerardo Mendizabal (01:06) Overcoming challenges in ovarian visualization: a case report of a magnetic resonance imaging-guided oocyte retrieval resulting in live birth with Samir Babayev (11:02)  Early pregnancy RhD-immune globulin practice patterns among REI physicians and the need for ASRM guidelines for RhIG administration with Nimerta Sandhu (20:30)  At-home and mail-in semen analysis: a critical review of scientific validation, regulatory oversight, and marketing claims with Juan Varela (25:00)  Preliminary analysis of a prospective cohort study of an epigenetic sperm quality test ("SpermQT") to predict success rates of ovarian stimulation treatment with Cassandra Roeca (31:05)  A discussion with the 2025 Ira and Ester Rosenwaks New Investigator Award recipient, Min Yang (34:50)  How combining medicine and coaching can empower patients through their fertility journey with Erica Bove (43:45) View Fertility and Sterility at https://www.fertstert.org/  

Fertility & Sterility on Air is at the 2025 ASRM Scientific Congress & Expo in San Antonio, Texas (Part 2)! In this episode, our hosts Kate Devine and Eve Feinberg cover: The impact of cannabis on reproductive health with Jason Hedges and Jamie Lo (01:06) Anti-Müllerian Hormone (AMH) as a therapeutic target in women's health with David Pépin (10:18)  A discussion with the 2025 ASRM Distinguished Researcher Award recipient, Denny Sakkas (18:32)  Outcomes for patients who underwent oocyte cryopreservation at age 35 years and older: results from a large, multi-center cohort with Michelle Bayefsky (26:10)  The SLEEP Study: Sleep length and euploid embryo transfer protocol using the Oura Ring to assess the effect of sleep parameters on transfer outcomes with Sarah Cromack (33:48)  Investigating the reproductive potential of non-mosaic segmental aneuploidy: a double-blinded, multicenter non-selection study of 176 single frozen embryo transfers with Stephanie Willson and Emily Mounts (44:08) View Fertility and Sterility at https://www.fertstert.org/  

Fertility & Sterility on Air is at the 2025 ASRM Scientific Congress & Expo in San Antonio, Texas (Part 1)! In this episode, our hosts Kate Devine, Blake Evans, and Micah Hill cover: Anne Steiner, the current Editor-in-Chief of F&S Reviews, and Ruben Alvero, the incoming Editor-in-Chief, discuss the journal's submission process and future directions (01:06) Complexity of genetics and available testing modalities with Mili Thakur (06:45)  Optimizing embryo utilization: cost effectiveness of cryopreservation in the face of legal and financial uncertainty with Allison Eubanks (16:25)  Optimizing pain control following oocyte retrieval - a randomized blinded placebo controlled trial assessing ketorolac efficacy and fresh embryo transfer outcomes with Marja Brolinson King and Laura Zalles (21:42)  Discussing the Fertility and Sterility Editorial Fellowship program with F&S's first Editorial Fellow, Allison Eubanks (30:22)  Beyond expert grading: comparing a fully automated AI system to five expert embryologists for embryo selection with Mohsen Bahrami (36:20) View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peek at this month's Fertility and Sterility! Articles discussed this month are:   (03:03) A Randomized Controlled Trial of Counseling and Educational methods on Preimplantation Genetic Testing for Aneuploidy (PGT-A) for in vitro fertilization (IVF) patients (14:02) Healthy euploid dizygotic twin birth after transfer of non-mosaic aneuploid embryos (25:05) Validity of completely omitting endocrine and ultrasound monitoring in hormone replacement therapy protocols for frozen embryo transfer in good-prognosis patients undergoing single blastocyst transfer (38:52) Cost-effectiveness of single euploid frozen embryo transfer in a true natural versus a hormonal replacement cycle (44:29) Modified Versions of Natural Frozen Embryo Transfers Do Not Impact Live Births (55:28) Soy consumption and the risk of laparoscopically confirmed endometriosis in a prospective cohort study (01:02:42) Optimizing In Vitro Maturation Outcomes of Oocytes Following Gonadotropin Priming in Premenarcheal Girls Undergoing Ovarian Tissue Cryopreservation View the November 2025, Volume 124 Issue 5 of Fertility and Sterility at https://www.fertstert.org/issue/S0015-0282(25)X0012-1 View Fertility and Sterility at https://www.fertstert.org/

Welcome to Fertility & Sterility Roundtable! Each month, we will host a discussion with the authors of "Views and Reviews" and "Fertile Battle" articles published in a recent issue of Fertility & Sterility.  This month, we welcome Dr. Brian Levine and Dr. Kate Schoyer to discuss if physicians should be facilitating gestational carrier arrangements in the absence of a medical indication, also known as elective surrogacy.  Dr. Brian Levine is the founding partner and practice director of CCRM New York, where he has helped countless families on their path to parenthood. Dr. Levine is also the founder of Nodal, the premier online gestational surrogacy platform, which connects intended parents and surrogates in a trusted and transparent way. Dr. Kate Schoyer is an Associate Professor of Obstetrics and Gynecology and Reproductive Endocrinology and Infertility at the Medical College of Wisconsin. She is the Director of the Division of Reproductive Endocrinology and Infertility and is the Medical Director of the Reproductive Medicine Center at Froedtert Hospital. Her research interests include factors contributing to success with ART, the impact of BMI, and therapies for patients with diminished ovarian reserve. View Fertility and Sterility at https://www.fertstert.org/  

In this month's Fertility & Sterility: Unplugged, we take a look at articles from F&S's sister journals! Topics this month include: circadian rhythm and reproductive health (04:34), fertility treatment outcomes after bariatric surgery (13:49), interleukin-22 balance and pregnancy (26:35), and mTOR inhibitors for fertility preservation in breast cancer (39:45). Consider This: https://www.fertstert.org/news-do/chronofertility-integrating-multi-timescale-chronobiology-into-fertility-research-and F&S Reports: https://www.fertstertreports.org/article/S2666-3341(25)00097-2/fulltext F&S Science: https://www.fertstertscience.org/article/S2666-335X(25)00065-5/fulltext F&S Reviews: https://www.fertstertreviews.org/article/S2666-5719(25)00011-8/abstract View the sister journals at: https://www.fertstertreviews.org https://www.fertstertreports.org https://www.fertstertscience.org    

Take a sneak peek at this month's Fertility & Sterility! Articles discussed this month are:   (04:48) Advanced maternal age was associated with an annual decline in reproductive success despite use of donor oocytes: a retrospective study (15:16) Developing a decision support tool to optimize oocyte thawing for producing at least three euploid blastocysts (23:47) Effect of denosumab on semen quality in infertile men selected by serum level of antimüllerian hormone: a randomized controlled trial (31:06) Progestin prime ovarian stimulation provides comparable outcomes to GnRH antagonist in donor cycles with vitrified oocytes (41:13) Impact on clinical outcomes of membership in the Society for Assisted Reproductive Technology (48:58) Linzagolix with and without hormonal add-back therapy for symptomatic uterine fibroids: PRIMROSE 1 & 2 long-term extension and withdrawal study (56:30) Cumulative pretrigger progesterone levels are not superior to single-day levels for predicting a failed cycle in fresh embryo transfer cycles View the October 2025, Volume 124 Issue 4 of Fertility and Sterility at https://www.fertstert.org/issue/S0015-0282(25)X0010-8 View Fertility and Sterility at https://www.fertstert.org/  

In this month's Fertility & Sterility: Unplugged, we take a look at articles from F&S's sister journals! Topics this month include: whether the optimal time interval for trigger varies depending on the trigger medication used (02:36), the mechanisms by which different trigger medications affect final oocyte maturation (16:05), how alcohol alters the blood-testis barrier function (31:10), and an analysis of the TikTok content specific to endometriosis-related infertility (45:15). F&S Reports: https://www.fertstertreports.org/article/S2666-3341(25)00114-X/fulltext   F&S Reviews: https://www.fertstertreviews.org/article/S2666-5719(25)00010-6/fulltext F&S Science:  https://www.fertstertscience.org/article/S2666-335X(25)00050-3/fulltext Consider This: https://www.fertstert.org/article/S0015-0282(24)00873-2/fulltext View the sister journals at: https://www.fertstertreviews.org https://www.fertstertreports.org https://www.fertstertscience.org  

Welcome to Fertility & Sterility Roundtable! Each month, we will host a discussion with the authors of "Views and Reviews" and "Fertile Battle" articles published in a recent issue of Fertility & Sterility.  This month, we welcome Dr. Lydia Hughes and Dr. Eric Widra to discuss the ethics of egg-sharing, or "split-cycles" for fertility preservation. This is where an egg donor freezes their eggs for their own future use for reduced or no cost in exchange for donating a portion of the cohort. Dr. Hughes is a second-year REI fellow at Northwestern University in Chicago, where she also completed her residency in Obstetrics and Gynecology. She earned her medical degree from the University of Alabama at Birmingham. Dr. Hughes's clinical and academic interests include reproductive ethics, PCOS, and ovarian aging.  Dr. Widra currently serves as Executive Senior Medical officer and Vice President, Development for Shady Grove Fertility and US Fertility, respectively.  He was formerly Chief Medical Officer of SG Fertility, and Associate Director of the Combined Federal Fellowship in Reproductive Endocrinology and Infertility, operated through the NIH, Walter Reed National Military Medical Center and SG Fertility. View Fertility and Sterility at https://www.fertstert.org/    

Fertility & Sterility on Air is at the European Society of Human Reproduction and Embryology 41st Annual Meeting in Paris, France (Part 2)! In this episode, our hosts Kate Devine, Eve Feinberg, and Micah Hill cover: Discussing the state of assisted reproductive technology in Brazil with Giuliano Bedoschi (01:01) Whole transcriptome and genome sequencing of standard embryo biopsies can potentially reduce failed euploid transfers with Kaylene Ready and Jeremy Grushcow (09:03)  The use of AI in ovarian stimulation with Eduardo Hariton (19:45)  Modeling embryonic adhesion at cellular resolution within a microfluidic endometrium-on-a-chip platform with Sofia Zaragozano (32:33)  Assessing the ploidy status of atypically fertilised embryos – recovery of embryos for potential clinical use with Sharyn Stock-Myer (40:41)  Role of micronutrients and probiotics supplementation on reproductive outcomes in an oocyte donation program with Sara Maggi and Silvia Bonta (42:47)  Male infertility, life expectancy, and long-term health risks: exploring what can sperm reveal about health with Omar Ammar (58:00) Mitochondrial DNA 'reversal' is common in children born following meiotic spindle transfer, potentially reducing the efficacy of mitochondrial replacement therapies with Munuse Savash (01:05:57) View Fertility and Sterility at https://www.fertstert.org/  

Fertility & Sterility on Air is at the European Society of Human Reproduction and Embryology 41st Annual Meeting in Paris, France (Part 1)! In this episode, our hosts Kate Devine, Eve Feinberg, and Micah Hill cover:  outcomes from programmed ovulatory frozen embryo transfer cycles vs. modified natural frozen embryo transfer cycles with Philippos Edimiris (0:56), non-invasive preimplantation genetic testing using metabolomics with Sofia Nunes (9:23), optimizing timing of modified natural cycle frozen embryo transfer cycles with Amelie Johansen and Kristine Løssl (17:46), mechanisms and consequences of ovarian aging with Francesca Duncan (27:18), comparing pregnancy loss rates in natural cycle vs. artificial cycle endometrial preparation prior to euploid embryo transfer with Caroline Roelens (38:24), and endometrial health and reproductive outcomes with Shari Mackens(49:44). View Fertility and Sterility at https://www.fertstert.org/  

Take a sneak peek at this month's Fertility & Sterility! Articles discussed this month are:   04:20 Poor intracytoplasmic sperm injection outcome in infertile males with azoospermia factor c microdeletions 10:17 Patients with a body mass index of ≥45 kg/m2 can safely undergo oocyte retrievals and anticipate similar assisted reproductive technology outcomes 21:26 Increased endometrial thickness up to 12 mm is associated with increased odds of live birth among fresh and frozen-thawed autologous transfers with or without preimplantation genetic testing 34:21 The chorionic bump is a predictor of miscarriage: a retrospective analysis of 13,656 in vitro fertilization pregnancies 47:01 Prospective validation of anti-Müllerian hormone cutoff to determine polycystic ovarian morphology: HARMONIA study 58:21 Effect of glucagon-like peptide 1 agonist medications on weight loss in patients with and without polycystic ovary syndrome View Fertility and Sterility at https://www.fertstert.org/