Tripping Over Love

In today's episode of Tripping Over Love, we sit down with Dr. John Krystal—Chair of Psychiatry at Yale and one of the pioneers behind ketamine's use in treating depression. If you've ever wondered how ketamine actually works, why it's so different from SSRIs, what happened with MDMA's FDA rejection, or whether esketamine is truly better than IV ketamine…this is the episode. Dr. Krystal explains: How ketamine became the first rapid-acting antidepressant Why it works when nothing else does The real difference between IV ketamine and esketamine (Spravato) How few people with treatment-resistant depression actually receive ketamine Why supervised clinical use is essential What the future of mental health treatment looks like (next-gen ketamine & non-hallucinogenic psychedelics) We also talk openly about our own mental health journeys—including how ketamine changed Keith's life and inspired the founding of a ketamine-assisted therapy clinic. This episode blends science, safety, personal experience, and the emerging landscape of psychedelic medicine. Subscribe for new episodes on relationships, psychedelics, and how to live with more presence, honesty, and self-leadership. If you or someone you love is in crisis, call 988. Watch Full Video: www.youtube.com/@TrippingOverLove Apple Podcasts: https://podcasts.apple.com/us/podcast/tripping-over-love/id1850974406 Spotify: https://open.spotify.com/show/6yl3TNTfBM1TutbETEKYNC Substack: https://trippingoverlove.substack.com/ Instagram: @trippingoverlovepodcast TikTok: @trippingoverlove Facebook: Tripping Over Love Podcast

This is the first of many behind-the-scenes episodes we're releasing at launch — a completely unstructured, unfiltered, lighthearted ramble recorded during the summer when rhubarb and strawberries are ripe for pie and we hit the ecstatic dance floor, sober-ish. There's no lesson plan. No expert interview. No theme. Just two people laughing at ourselves and talking about everything from rage golf, late-night eating, kambucha recipes that involve climbing the magnolia tree in the yard, pleasing others, and why therapy wasn't working (or was it?) If you want to know what we're actually like off-mic, this is it. Subscribe for more structured episodes… and the occasional meandering romp into our stream of consciousness. Substack: https://trippingoverlove.substack.com Instagram: @trippingoverlovepodcast TikTok: @trippingoverlove Facebook: Tripping Over Love Podcast

In today's episode of Tripping Over Love, we talk with Dr. Tammy Nelson — sex therapist, author of Getting the Sex You Want and Open Monogamy, and one of the most influential voices in modern sexuality and relationships. Tammy joins us to talk about why couples struggle with sex and communication, open monogamy and the continuum of commitment, how to rethink monogamy in a digital age, what porn, kink and sex-tech are teaching us about intimacy, what therapists get wrong about sex, how ketamine and psychedelics accelerate relational healing, how menopause and perimenopause are misrepresented, and why pleasure remains one of the most radical forms of healing. This conversation covers sex, desire, psychedelics, monogamy, trauma, and long-term relational repair — with Tammy's signature blend of clarity, warmth, and zero shame. JOIN OUR SUBSTACK https://trippingoverlove.substack.com/ FOLLOW US Instagram: @trippingoverlovepodcast TikTok: @trippingoverlove Facebook: https://www.facebook.com/TrippingOverLovePodcast/    

What really happens inside an open marriage, beyond the fantasies, fears, and assumptions? Author Molly Roden Winter joins us to share the raw truth behind her memoir "More: A Memoir of Open Marriage," including jealousy spirals, boundary mishaps, sex that worked (and sex that very much didn't), and the emotional renovations that reshaped her 26-year marriage. Molly talks about the early chaos of opening her relationship, the surprising ways dating men differed from dating women, why rules always break before you do, and how she and her husband grew, built, and redefined trust. She also opens up about her psilocybin journey, forgiveness, what monogamy means after 17 years open, and why desire often has more to do with honesty than novelty. If you're curious about non-monogamy, wrestling with jealousy, or wondering what open marriage actually looks like outside of social media narratives, this conversation is real, funny, and disarmingly human. JOIN OUR SUBSTACK https://trippingoverlove.substack.com/ FOLLOW US Instagram: @trippingoverlovepodcast TikTok: @trippingoverlove Facebook: https://www.facebook.com/TrippingOverLovePodcast/

I'm launching Tripping Over Love on Tuesday, November 25th. It's the podcast about breakups, breakdowns, and breakthroughs. We're Courtney Laydon, former journalist, and Keith Miller, a marriage and IFS therapist who found each other while tripping over love.  We ask one big question: What if the secret to lasting love isn't getting it right… but getting real? Next week, we're launching our first four episodes—and they're a ride: Molly Roden Winter on open marriage, jealousy, honesty, and why real intimacy is way less "sexy" and way more human. Dr. Tammy Nelson on sex, intimacy, psychedelic healing, and how ketamine can open more than just your mind. Dr. John Krystal, one of the inventors of intranasal ketamine, on the future of psychedelic medicine And wild stories from the Keith and Courtney dating experiences...including one that became "ecstatic" and opened Keith up to the kind of dance parties he missed out on as a teen Tripping Over Love is not a podcast about perfect love. It's about conscious love—the kind that asks you to laugh, feel, grow, and sometimes completely fall apart. Subscribe now. The mess begins next week. READ + LISTEN + FOLLOW  Substack: https://trippingoverlove.substack.com/  Instagram: @trippingoverlovepodcast  TikTok: @trippingoverlove  Facebook: https://www.facebook.com/TrippingOverLovePodcast/  

In this episode, Keith and Courtney pull back the curtain on the weekend that surprised them both. It starts on an eclectic dance floor—no choreography, no rules, just bodies moving, and Keith learning new ways to move his hips. From there, they hit the road to Boston, where the long drive opened up conversations about desire, safety, and the ways psychedelics and IFS have changed how they show up for each other. Plus...strawberry rhubarb pie!