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Off The Charts
Off The Charts
Author: Dr. Bobby Parmar, ND
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How many podcasts could there poddibly be about correcting medical misinformation now?
Why would I add my voice to the chorus that can be so deafening?
I've had 18+ years of experience seeing tons and treating everything from A to Z and lemme tell you there's plenty I can add to the conversation. Dive with me into the science of medicine with a heaping side of sass and spice.
7 Episodes
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Fertility testing has become mainstream — but most women still don’t fully understand what those results actually mean.
In this episode, Dr. Parmar sits down with Dr. Alana Shaw, ND to unpack what fertility testing actually tells you — and what it doesn’t — in a world flooded with online fertility advice.
They break down AMH, antral follicle count, and pelvic/endovaginal ultrasound as screening tools, then connect it to the real-life questions women are asking:
“Should I test before I even start trying?”
“Does low AMH mean infertility?”
“Why is IVF a numbers game?”
They also touch on the bigger clinical context — including painful periods that get normalized, and why better screening and better explanations matter.
Dr. Shaw also shares about her clinical work at Mint Integrative Health (Vancouver).
WHAT YOU'LL LEARN
What AMH measures (ovarian reserve) vs what it doesn’t measure (natural fertility prediction)
Why low AMH ≠ “you’re infertile”
Why IVF outcomes are a “numbers game”
What antral follicle count (AFC) is and why it’s often paired with AMH
Why age tends to predict egg quality better than AMH does
What clinicians can learn from endovaginal ultrasound (cysts, endometriomas, fibroids, adenomyosis screening)
Who fertility “pre-screening” may be most helpful for (especially people who want kids but don’t have a pathway yet)
TIMESTAMPS
00:00 — Painful periods being normalized
02:00 — “Fertility online” and why people are confused
24:30 — Who should consider prescreening
25:50 — Low AMH: what it means (and what it doesn’t)
26:10 — IVF is a numbers game
35:45 — AFC + endovaginal ultrasound explained
51:50 — IUDs as “good medicine” / non-contraceptive use
⚠️ This video is for educational and informational purposes only and is not medical advice. Always consult a qualified healthcare provider before starting or stopping medication.
TOP REFERENCES:
Ovarian Reserve Testing (AMH, AFC) + Interpretation ASRM Practice Committee Testing and interpreting measures of ovarian reserve (Committee Opinion, 2020) https://www.asrm.org/practice-guidance/practice-committee-documents/testing-and-interpreting-measures-of-ovarian-reserve-a-committee-opinion-2020/
NCBI Bookshelf (Endotext) Ovarian Reserve Testing https://www.ncbi.nlm.nih.gov/books/NBK279058/
ACOG Practice Bulletin Long-Acting Reversible Contraception: Implants and Intrauterine Devices https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2017/11/long-acting-reversible-contraception-implants-and-intrauterine-devices
Heavy Menstrual Bleeding Guidance NICE Guideline NG88 (PDF) Heavy menstrual bleeding: assessment and management https://www.nice.org.uk/guidance/ng88/resources/heavy-menstrual-bleeding-assessment-and-management-pdf-1837701412549
Endometriosis (Prevalence + Overview) World Health Organization (WHO) Fact Sheet Endometriosis https://www.who.int/news-room/fact-sheets/detail/endometriosis
CONNECT WITH GRAVITY HEALTH
Website → https://www.gravityhealthclinics.com/
Book a Consult → https://gravityhealth.janeapp.com/
Mint Reproductive Health → https://mintreproductivehealth.com/
Dr. Alana Shaw → https://alanashawnd.com/
FOLLOW US
Instagram (Clinic) → https://www.instagram.com/gravityhealthclinics/
Dr. Bobby Parmar → https://www.instagram.com/docparmar_nd/
Dr. Paul Maximus → https://www.instagram.com/drmaximus/
Mint Reproductive Health → https://www.instagram.com/mintreproductivehealth/
Off the Charts is a podcast by Gravity Health, created for general informational and educational purposes only. It does not constitute the practice of medicine, nursing, or any other healthcare service, and should not be taken as medical advice. Listening to this podcast does not create a doctor–patient relationship.
Listeners should always seek the guidance of qualified healthcare professionals regarding any medical condition or treatment.
For more information about content use and disclaimers, please visit:
https://www.gravityhealthclinics.com/terms-of-use
https://www.gravityhealthclinics.com/medical-disclaimer
Many people wonder whether antidepressants are the right choice — but the conversation is often oversimplified, stigmatized, or incomplete.
In this episode of Off the Charts, Dr. Bobby Parmar, ND takes a grounded, compassionate look at antidepressants: how they actually work in the body, why they’re prescribed for more than depression, and how hormones, pain, life stress, and brain chemistry all play a role in mental health decisions.
WHAT YOU'LL LEARN
How antidepressants affect serotonin, dopamine, and norepinephrine
Why antidepressants are used beyond depression, including pain, PMDD, and postpartum mood changes
Common concerns around weight gain and side effects
How clinicians think about matching medications to symptoms
The difference between dependence and discontinuation
What to consider if you’re thinking about starting — or eventually coming off — antidepressants
This conversation is for anyone who wants a clearer, more honest understanding of antidepressants without fear, judgment, or oversimplification.
TIMESTAMPS
0:00 – Why this question matters
0:48 – Why a holistic doctor prescribes antidepressants
5:20 – When lifestyle changes aren’t enough
9:09 – How antidepressants work in the brain
12:05 – Weight gain, metabolism, and SSRIs
15:48 – Side effects and early tolerance
18:22 – Matching antidepressants to symptoms
22:12 – Hormones, depression, and sex differences
24:12 – PMDD and why SSRIs are used
28:43 – Postpartum depression and hormonal shifts
31:30 – Hormones vs depression — does the distinction matter?
33:59 – Antidepressants and chronic pain
39:28 – Dependence vs discontinuation
45:55 – When and how tapering is considered
48:06 – Treatment resistance and alternatives
52:38 – Reducing stigma and fear around antidepressants
⚠️ This video is for educational and informational purposes only and is not medical advice. Always consult a qualified healthcare provider before starting or stopping medication.
TOP REFERENCES:
Antidepressant Medications (Overview)
National Institute of Mental Health (NIMH): https://www.nimh.nih.gov/health/topics/mental-health-medications
Choosing the Right Antidepressant
Mayo Clinic: https://www.mayoclinic.org/diseases-conditions/depression/in-depth/antidepressants/art-20046273
Antidepressant Discontinuation Syndrome
American Family Physician: https://www.aafp.org/pubs/afp/issues/2006/0801/p449.html
Going Off Antidepressants: What to Know
Harvard Health Publishing: https://www.health.harvard.edu/diseases-and-conditions/going-off-antidepressants
Premenstrual Dysphoric Disorder (PMDD)
Johns Hopkins Medicine: https://www.hopkinsmedicine.org/health/conditions-and-diseases/premenstrual-dysphoric-disorder-pmdd
Antidepressants for Chronic Pain
Mayo Clinic: https://www.mayoclinic.org/diseases-conditions/back-pain/in-depth/pain-medications/art-20045647
Pharmacogenomics & Medication Metabolism
Clinical Pharmacogenetics Implementation Consortium (CPIC): https://cpicpgx.org
CONNECT WITH GRAVITY HEALTH
Website → https://www.gravityhealthclinics.com/
Book a Consult → https://gravityhealth.janeapp.com/
FOLLOW US
Instagram → https://www.instagram.com/gravityhealthclinics/
Dr. Bobby Parmar, ND → https://www.instagram.com/docparmar_nd/
Dr. Paul Maximus, ND → https://www.instagram.com/drmaximus/
Off the Charts is a podcast by Gravity Health, created for general informational and educational purposes only. It does not constitute the practice of medicine, nursing, or any other healthcare service, and should not be taken as medical advice. Listening to this podcast does not create a doctor–patient relationship.
Listeners should always seek the guidance of qualified healthcare professionals regarding any medical condition or treatment.
For more information about content use and disclaimers, please visit:
https://www.gravityhealthclinics.com/terms-of-use
https://www.gravityhealthclinics.com/medical-disclaimer
In this episode of Off the Charts, Dr. Bobby Parmar, ND and Dr. Paul Maximus, ND sit down with Dr. Jordan Robertson, ND, founder of The Confident Clinician, for a grounded conversation on what leadership actually looks like in modern clinical practice.
Using the Confident Clinician framework, the discussion examines why confidence in medicine is built through judgment, systems, and decision-making—not busyness, credentials, or hustle. Together, they explore why linear growth models break under ambitious goals, how clinicians can expand their impact without burning out, and what it means to lead responsibly as practices and platforms scale.
Dr. Robertson shares candid insights on betting on yourself before certainty, building systems instead of relying on individual capacity, and why the most effective clinicians think differently about growth, responsibility, and long-term impact. The conversation also addresses the realities faced by under-resourced clinicians, the importance of dialogue and accountability within professional communities, and how emerging tools like AI should be used to support—rather than replace—clinical judgment.
Rather than focusing on trends or quick fixes, this episode positions leadership as a daily practice and scalability as a design challenge. It reflects the core philosophy of The Confident Clinician: that confidence is earned through clear thinking, strong systems, and intentional leadership.
This discussion is especially relevant for clinicians navigating growth, leadership responsibilities, or systemic constraints, and for anyone interested in how modern medicine can evolve thoughtfully without compromising trust, expertise, or integrity.
WHAT YOU'LL LEARN
Why getting “busier” often leads to diminishing returns in clinical practice
What leadership looks like when decisions are made without perfect conditions
How clinicians can scale their impact without relying on hustle or burnout
The difference between linear growth and system-level thinking in healthcare
Why under-resourced clinicians experience stress, criticism, and negativity differently
How to approach growth as an ecosystem design problem rather than an individual effort
The role of judgment, communication, and leadership in a future shaped by AI
Why betting on yourself — and building the right support systems — matters in long-term clinical impact
TIMESTAMPS
0:00 – Leadership Is a Daily Choice
4:07 – Breaking Rules to Lead Better
10:05 – Building Outside Broken Systems
15:48 – Under-Resourced Clinicians
19:47 – Leadership Means Disappointment
23:43 – Saying Yes Before Certainty
29:04 – Why 10x Requires Different Thinking
34:03 – Designing Systems for Scale
37:59 – AI Won’t Replace Clinicians
41:51 – Sandboxed AI in Medicine
45:07 – What Patients Actually Need
58:41 – Raising the Standard in ND Medicine
1:06:02 – Final Takeaways
TOP REFERENCES
The Confident Clinician - https://confidentclinicianclub.com/
Dr. Jordan Robertson, ND - https://drjordannd.com/
This resource page is for educational purposes only and does not constitute medical advice.
CONNECT WITH GRAVITY HEALTH
Website → https://www.gravityhealthclinics.com/
Book a Consult → https://gravityhealth.janeapp.com/
FOLLOW US
Instagram → https://www.instagram.com/gravityhealthclinics/
Dr. Bobby Parmar, ND → https://www.instagram.com/docparmar_nd/
Dr. Paul Maximus, ND → https://www.instagram.com/drmaximus/
Dr. Jordan Robertson, ND → https://www.instagram.com/drjordannd/
Off the Charts is a podcast by Gravity Health, created for general informational and educational purposes only. It does not constitute the practice of medicine, nursing, or any other healthcare service, and should not be taken as medical advice. Listening to this podcast does not create a doctor–patient relationship. Listeners should always seek the guidance of qualified healthcare professionals regarding any medical condition or treatment.
For more information about content use and disclaimers, please visit:
https://www.gravityhealthclinics.com/terms-of-use
https://www.gravityhealthclinics.com/medical-disclaimer
Iron deficiency is one of the most common and most misunderstood medical issues affecting women today.
In this episode of Off the Charts, Dr. Bobby Parmar, ND and Dr. Paul Maximus, ND break down why so many patients are told their labs are “normal” while they continue to experience exhaustion, brain fog, hair loss, chronic pain, mood changes, and low libido.
The conversation explores how laboratory reference ranges differ from clinical reality, why iron deficiency is routinely missed until it becomes anemia, and how outdated screening practices disproportionately affect women. This is especially true for those with heavy periods, perimenopause, inflammatory conditions, plant-based diets, or absorption issues.
Dr. Parmar and Dr. Maximus explain why oral iron often fails, why symptoms can persist well above traditional ferritin cutoffs, and why IV iron is positioned as a system-level solution rather than unnecessary intervention.
The discussion covers bone marrow iron stores, ferritin targets, pregnancy and postpartum depletion, libido, mental health, and energy regulation. This episode challenges the idea that feeling tired, foggy, or unwell is simply part of being a woman.
If you have ever been told your labs are fine but your body says otherwise, this conversation puts iron deficiency back where it belongs: front and center.
WHAT YOU’LL LEARN
Why iron deficiency is often missed until anemia
The difference between lab reference ranges and clinical thresholds
Why symptoms can exist above “normal” ferritin levels
Why oral iron frequently fails
How menstruation, pregnancy, and inflammation affect iron
The role of iron in energy, mood, libido, and cognition
Why IV iron is framed as system relief
What patients should ask for and what doctors should reconsider
TIMESTAMPS
00:00 Introduction and hot open
02:00 Why iron deficiency is missed in women
05:00 Lab reference ranges versus clinical thresholds
08:00 Ferritin, bone marrow iron, and symptoms
12:00 Oral iron failure and absorption issues
15:00 Menstrual blood loss, pregnancy, and iron depletion
18:00 Iron, neurotransmitters, and libido
20:00 Addressing criticism around iron infusions
23:00 Anemia as the final stage of deficiency
25:00 Cost, benefits coverage, and private pay realities
27:00 Why the system does not emphasize iron deficiency
28:00 Closing thoughts: know your number and fix it
TOP REFERENCES
Iron Rx Universe – IV iron and ferritin education https://ironrxuniverse.com
Iron deficiency without anemia – clinical review (NIH / PMC) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986027/
Heavy menstrual bleeding and iron deficiency (ACOG) https://www.acog.org
Iron deficiency in pregnancy (WHO / PMC) https://www.ncbi.nlm.nih.gov/pmc/
This resource page is for educational purposes only and does not constitute medical advice.
CONNECT WITH GRAVITY HEALTH
Website → https://www.gravityhealthclinics.com/
Book a Consult → https://gravityhealth.janeapp.com/
Mint Reproductive Health → https://mintreproductivehealth.com/
FOLLOW US
Instagram → https://www.instagram.com/gravityhealthclinics/
Dr. Bobby Parmar → https://www.instagram.com/docparmar_nd/
Dr. Paul Maximus → https://www.instagram.com/drmaximus/
Off the Charts is a podcast by Gravity Health, created for general informational and educational purposes only. It does not constitute the practice of medicine, nursing, or any other healthcare service, and should not be taken as medical advice. Listening to this podcast does not create a doctor–patient relationship. Listeners should always seek the guidance of qualified healthcare professionals regarding any medical condition or treatment.
For more information about content use and disclaimers, please visit:
https://www.gravityhealthclinics.com/terms-of-use
https://www.gravityhealthclinics.com/medical-disclaimer
Medicine wasn’t built for women — and today, the consequences show up in every corner of healthcare.
From misdiagnosed pain to delayed diagnoses, from biased research to outdated medical training, women around the world are still fighting to be heard, believed, and properly treated.
In this episode, Dr. Bobby Parmar, ND sits down with activist and storyteller Karen “Kaz” Twomey for a powerful conversation about the gender data gap and how it continues to shape women’s health outcomes. Together, they explore why conditions like endometriosis, PCOS, perimenopause, and iron deficiency are so often dismissed or overlooked; how historical bias has shaped modern gynecology; and why women still struggle to find accurate information, compassionate care, and timely diagnosis.
This episode dives into the cultural, scientific, and systemic roots of medical sexism, the lingering influence of the WHI hormone therapy study, and the growing movement of women reclaiming their own health literacy through social media, advocacy, and community education. If you’ve ever wondered why women’s symptoms are minimized, why diagnostic delays are so common, or why women’s health research lags behind — this conversation pulls back the curtain.
WHAT YOU’LL LEARN
Why women’s symptoms are dismissed
The gender data gap • Endometriosis & PCOS
Pain bias in gynecology
Iron deficiency & pregnancy
Estrogen fear & the WHI study
Ireland’s Repeal movement
How culture shapes women’s care
What needs to change in medicine
TIMESTAMPS
00:00 – Introduction
01:00 – The gender data gap
05:00 – Endometriosis, PCOS, & delayed diagnosis
10:00 – Iron deficiency & overlooked symptoms
15:00 – The WHI study & hormone therapy confusion
20:00 – Social media & women reclaiming health literacy
25:00 – Pain bias & gynecology
30:00 – Ireland’s Repeal movement & reproductive rights
40:00 – The roots of medical misogyny
45:00 – What better care looks like
TOP REFERENCES
Invisible Women (Caroline Criado Perez) https://www.penguinrandomhouse.com/books/610351/invisible-women-by-caroline-criado-perez/
The Menopause Society (formerly NAMS) https://www.menopause.org/
WHI Hormone Therapy Study (JAMA) https://jamanetwork.com/journals/jama/fullarticle/195120
Endometriosis Diagnostic Delay — Review (NIH / PMC) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752380/
PCOS Rotterdam Criteria Summary (NIH / PMC) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387639/
IUD Insertion Pain Research (ACOG) https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2016/07/clinical-guidance-for-IUDs
This resource page is for educational purposes only and does not constitute medical advice.
CONNECT WITH GRAVITY HEALTH
Website → https://www.gravityhealthclinics.com/
Book a Consult → https://gravityhealth.janeapp.com/
Mint Reproductive Health → https://mintreproductivehealth.com/
FOLLOW US
Instagram → https://www.instagram.com/gravityhealthclinics/
Dr. Bobby Parmar → https://www.instagram.com/docparmar_nd/
Dr. Paul Maximus → https://www.instagram.com/drmaximus/
Kaz Twomey → https://www.instagram.com/kaztwomey/?hl=en
Off the Charts is a podcast by Gravity Health, created for general informational and educational purposes only. It does not constitute the practice of medicine, nursing, or any other healthcare service, and should not be taken as medical advice. Listening to this podcast does not create a doctor–patient relationship. Listeners should always seek the guidance of qualified healthcare professionals regarding any medical condition or treatment.
For more information about content use and disclaimers, please visit:
https://www.gravityhealthclinics.com/terms-of-use
https://www.gravityhealthclinics.com/medical-disclaimer
Understanding how estrogen affects breast cancer risk is one of the most confusing and highly searched topics in women’s health. In this episode of Off the Charts, Dr. Bobby Parmar, ND breaks down the science behind estrogen, breast density, hormone therapy (HRT), IUDs, birth control, IVF, pregnancy timing, breastfeeding, and other factors that shape breast cancer risk throughout a woman’s life.
We explain what “lifetime estrogen exposure” means, why early periods and late menopause matter, and how breast density, alcohol, height, metabolic health, and reproductive history all contribute to risk in different ways. We also clarify one of the biggest misconceptions circulating online: estrogen-only menopausal hormone therapy after hysterectomy is associated with lower breast cancer risk according to large randomized trials.
This episode gives women a clear, evidence-based understanding of breast cancer risk factors—without fear-based messaging or misinformation.
WHAT YOU’LL LEARN
How estrogen influences breast cancer risk across the lifespan
Estrogen’s benefits for bone, brain, metabolic and cardiovascular health
The truth about perimenopause, menopause and hormone therapy (HRT)
Breast density, BI-RADS categories and how density affects screening accuracy
Family history, atypia and combined breast cancer risk
Alcohol, height, growth hormones and metabolic contributors
Pregnancy timing, breastfeeding cycles and breast tissue biology
What studies actually show about IUDs, birth control and IVF
What women can and cannot control when it comes to breast cancer prevention
TOPICS COVERED (TIMELINE STYLE)
Why estrogen is misunderstood
What “lifetime estrogen exposure” really means
Menopause, HRT and clearing the confusion
Breast density, BI-RADS and cancer detection
Family history, atypia and stacked risks
How breast density changes with age
Alcohol as a Group 1 carcinogen and what studies show
Does alcohol type matter?
Height, growth hormones and cancer risk
Metabolic health, inflammation and early-life factors
Pregnancy timing and why age matters
Never having kids (nulliparity)
How breastfeeding changes breast tissue
What it means if you cannot breastfeed
IVF hormones and breast cancer risk
Birth control, hormonal IUDs and real-world numbers
Misinformation, fear-based messaging and how to understand your personal risk
EPISODE RESOURCES AND REFERENCES
Off the Charts provides a companion reference page for every episode to support transparency and evidence-based discussion. Key sources for Episode 2 include Frontiers in Oncology, The Lancet, Nature, the National Cancer Institute, the Canadian Cancer Society, FORCE XRAY, Susan G. Komen, Radiopaedia and the American College of Radiology (BI-RADS).
Primary studies and clinical resources:
Frontiers in Oncology – Estrogen Effects on the Mammary Gland https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2017.00110/full
PubMed – Estrogen-Alone Therapy and Breast Cancer Incidence (2024) https://pubmed.ncbi.nlm.nih.gov/38653905/
FORCE XRAY – Estrogen-Only HRT and Breast Cancer https://www.facingourrisk.org/XRAY/estrogen-without-progesterone-as-HRT-may-lower-breast-cancer
Canadian Cancer Society – Breast Density https://www.cancer.ca/en/treatments/tests-and-procedures/mammography/breast-density
National Cancer Institute – Reproductive History and Cancer https://www.cancer.gov/about-cancer/causes-prevention/risk/hormones/reproductive-history-fact-sheet
Nature – Pregnancy Duration and Breast Cancer Risk https://www.nature.com/articles/s41467-018-06748-3
Susan G. Komen – Age at First Childbirth https://www.komen.org/breast-cancer/risk-factor/age-at-first-childbirth
Radiopaedia – Breast Density Classification https://radiopaedia.org/articles/breast-density-classification
American College of Radiology – BI-RADS https://www.acr.org/Clinical-Resources/Clinical-Tools-and-Reference/Reporting-and-Data-Systems/BI-RADS
CONNECT WITH GRAVITY HEALTH
Website: https://www.gravityhealthclinics.com/ Book a Consult: https://gravityhealth.janeapp.com/ Mint Reproductive Health: https://mintreproductivehealth.com/
FOLLOW US
Instagram (Clinic): https://www.instagram.com/gravityhealthclinics/ Dr. Bobby Parmar: https://www.instagram.com/docparmar_nd/ Dr. Paul Maximus: https://www.instagram.com/drmaximus/
DISCLAIMER
Off the Charts is a podcast by Gravity Health created for general informational and educational purposes only. It does not constitute medical advice, diagnosis or treatment. Listening to this podcast does not establish a doctor–patient relationship. Always seek the guidance of a qualified healthcare professional regarding your personal health concerns.
Terms of Use: https://www.gravityhealthclinics.com/terms-of-use Medical Disclaimer: https://www.gravityhealthclinics.com/medical-disclaimer
Off the Charts – Episode 001
Why Everyone’s on GLP-1s (But No One Admits It)
With Dr. Bobby Parmar and Dr. Paul Maximus Brought to you by Gravity Health
“Behind the hype and hashtags, millions of people are quietly reshaping their health with GLP-1s, but the stigma hasn’t caught up to the science.”
Ozempic®, Mounjaro™, and other GLP-1 medications are changing how the world thinks about metabolism, weight, and longevity — but not without controversy.
In this conversation, Dr. Bobby Parmar and Dr. Paul Maximus explore how these drugs went from diabetes treatments to cultural lightning rods. They dig into what science really says about GLP-1s, why moral bias still shapes how we talk about obesity, and what this shift means for the future of health and medicine.
You’ll walk away with a deeper understanding of the biology behind appetite, the psychology of shame, and how longevity isn’t just about living longer — it’s about living better.
What You’ll Learn
The physiological role of GLP-1 hormones in regulating hunger, satiety, and blood sugar
Why these treatments are helping patients with metabolic and cardiovascular disease — not just weight
The history of fat-shaming and why stigma still affects treatment access
How obesity is now understood as a chronic, relapsing condition — not a personal failure
What the research shows about long-term safety, muscle preservation, and sustained metabolic improvement
Timestamps
0:00 Welcome to Off the Charts: The truth about GLP-1s and Ozempic 0:52 Why people hide their use of Ozempic and Mounjaro 2:52 Shame, willpower, and moral judgment in weight loss 4:55 Obesity as a disease — from circus cages to modern medicine 8:16 Fatphobia in healthcare and everyday life 9:13 Food noise, dopamine, and how our brains drive eating behavior 10:33 It’s not willpower — how biology shapes weight 13:55 The “cheating” narrative and natural vs pharmaceutical myths 15:31 The Gila monster story — how nature led to GLP-1 discovery 21:47 The rise of GLP-1 drugs and the billion-dollar shift 27:28 Why some doctors won’t prescribe Ozempic 32:30 Debunking “dangerous side effect” myths 37:27 Chronic disease, longevity, and why GLP-1s are for life 44:15 Muscle loss myths — what actually happens on Ozempic 48:38 Closing thoughts — send us your questions and hot takes
Episode Resources & References
To maintain transparency and support evidence-based discussion, every Off the Charts episode includes a companion page listing all primary research, clinical trials, and cultural references mentioned in the conversation.
These references include publications from the New England Journal of Medicine, Physiological Reviews, the FDA, Obesity Canada, and more.
Top References
1️⃣ Holst JJ (2007). The physiology of glucagon-like peptide-1 (GLP-1). Physiological Reviews. 🔗 https://journals.physiology.org/doi/full/10.1152/physrev.00034.2006
2️⃣ Drucker DJ (2018). Mechanisms of action and therapeutic application of GLP-1 and GIP. Cell Metabolism. 🔗 https://pubmed.ncbi.nlm.nih.gov/29617641/
3️⃣ Liraglutide and cardiovascular outcomes in type 2 diabetes. (2016). New England Journal of Medicine. 🔗 https://www.nejm.org/doi/full/10.1056/NEJMoa1603827
4️⃣ U.S. Food and Drug Administration (2024). FDA approves first treatment to reduce risk of serious heart problems in adults with obesity or overweight. 🔗 https://www.fda.gov/news-events/press-announcements/fda-approves-first-treatment-reduce-risk-serious-heart-problems-specifically-adults-obesity-or
5️⃣ Obesity Canada (2025). Recognizing and reducing weight bias in obesity management. 🔗 https://obesitycanada.ca/wp-content/uploads/2025/03/1-Canadian-Adult-Obesity-CPG-Reducing-Weight-Bias-Stigma.pdf
This resource page is for educational purposes only and does not constitute medical advice.
Connect with Gravity Health
Website → https://www.gravityhealthclinics.com/ YouTube → Watch on YouTubeBook a Consult → https://gravityhealth.janeapp.com/
Follow Us
Instagram → https://www.instagram.com/gravityhealthclinics/ Dr. Bobby Parmar → https://www.instagram.com/docparmar_nd/ Dr. Paul Maximus → https://www.instagram.com/drmaximus/
Off the Charts is a podcast by Gravity Health, created for general informational and educational purposes only. It does not constitute the practice of medicine, nursing, or any other healthcare service and should not be taken as medical advice. Listening to this podcast does not create a doctor–patient relationship.
Listeners should always seek the guidance of qualified healthcare professionals regarding any medical condition or treatment.
For more information about content use and disclaimers, please visit: https://www.gravityhealthclinics.com/terms-of-use https://www.gravityhealthclinics.com/medical-disclaimer




