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Welcome to Innovating Clinical Trials, the podcast designed for clinical research professionals eager to deepen their understanding of clinical trials through concise, insightful segments. Join your hosts, Liam Eves and Ted Trafford, as they uncover the core issues in clinical research, reflect on the industry, and challenge conventional wisdom.
Ted Trafford - https://probitymedical.com/
With 30 years of experience in clinical research, Ted serves as the Director of Business Development, driving business growth and leading Feasibility and Site Relationship teams at Probity Medical Research, a clinical trial site administrative support company with a consortium of 75+ sites across four countries. As a writer and speaker, Ted contributes to thought leadership and strategic initiatives in the clinical trials industry, leveraging his extensive experience and creative approach to drive meaningful discussion and progress for Sponsors, CROs, Sites and Technology Vendors.
Liam Eves - https://www.theendpointpodcast.com/
Liam's held executive roles in SMOs and CROs, and led all major functions of trial delivery. His journey into the field began unexpectedly after an injury ended his career as a professional footballer. Over the years Liam has optimized trial delivery methods / systems for effective enrollment and trial delivery. Currently, he focuses on building and advising companies in the clinical trial space.
Opinions expressed are those of the participants and not their employers.
38 Episodes
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Eligibility criteria are meant to bring clarity to clinical trials, but in practice, they often do the opposite. In this episode of Innovating Clinical Trials, Liam and Ted unpack how poorly worded, ambiguous, or misaligned eligibility criteria quietly slow enrollment, frustrate sites, and introduce risk later in development. They explore: - Why small wording choices create big downstream problems - How “gray areas” force sites into interpretation rather than execution - The disconnect b...
In this episode, Liam and Ted unpack why enrollment behaves more like an operating system rather than a standalone process. They explore the question of ownership, the role sponsors play through protocol design, and how operational practices, healthcare realities, and human behavior all influence who ultimately makes it into a study. The conversation moves through multiple lenses from eligibility criteria and healthcare documentation to behavioral science, site motivation, patient experience...
In this episode of Innovating Clinical Trials, Liam and Ted explore why building strong relationships with clinical trial sites requires more than dedicated relationship teams, it requires fixing problems at their source. They discuss how many site challenges stem from outdated processes, one-sided agreements, and preventable operational friction that relationship teams are left to manage after the fact. Using real-world examples from confidentiality agreements to lab and portal issues, the ...
In this episode of Innovating Clinical Trials, Liam and Ted explore what determines the trajectory of a clinical trial and why success often depends on preparation, collaboration, and the ability to adapt when things don’t go as planned. They discuss how factors outside a site’s control, such as vendor selection and monitoring approaches, can significantly influence trial momentum. Through real-world examples, the conversation highlights how thoughtful planning, supportive site interactions,...
In this episode of Innovating Clinical Trials, Liam and Ted challenge a familiar question in clinical research: “How do we increase enrollment?” Instead, they argue that progress starts by asking a better one- “What makes enrollment challenging in the first place?” They explore how study design, existing therapies, operational factors, and most importantly, the lived experience of participants and their families all shape recruitment outcomes. Ted shares a practical framework for slowing dow...
In this episode of Innovating Clinical Trials, Liam and Ted explore why clinical research is, at its core, a people-driven business. Drawing on real-world experiences from both patient and site perspectives, they discuss how trust, communication, and human connection directly influence recruitment, retention, and study success. From participant consent conversations to site selection and prioritization, the discussion highlights how “soft skills” often have a measurable impact on trial perfo...
Welcome to Innovating Clinical Trials, the podcast designed for clinical research professionals eager to deepen their understanding of clinical trials through concise, insightful segments. Join your hosts, Liam Eves and Ted Trafford, as they uncover the core issues in clinical research, reflect on the industry, and challenge conventional wisdom. In this episode, Liam and Ted reveal how minor, unexpected requests often snowball into a significant site burden. They dive into why scope creep occ...
Welcome to Innovating Clinical Trials, the podcast designed for clinical research professionals eager to deepen their understanding of clinical trials through concise, insightful segments. Join your hosts, Liam Eves and Ted Trafford, as they uncover the core issues in clinical research, reflect on the industry, and challenge conventional wisdom. In this episode, Liam and Ted explore what it truly means to be a sponsor of choice for clinical trial sites. They discuss how communication gaps bet...
Welcome to Innovating Clinical Trials, the podcast designed for clinical research professionals eager to deepen their understanding of clinical trials through concise, insightful segments. Join your hosts, Liam Eves and Ted Trafford, as they uncover the core issues in clinical research, reflect on the industry, and challenge conventional wisdom. Season 2 kicks off with Liam and Ted exploring what it means to be a “Sponsor of Choice.” Through thoughtful analogies and real-world insights. They ...
In this episode, we explore a crucial aspect of clinical research – the transparency and accuracy of metrics collected by big pharma and CROs. You'll learn about the importance of sharing key performance indicators (KPIs) and how this transparency can lead to improved performance and better clinical trial outcomes. We'll discuss common metrics tracked, potential errors, and practical advice for both research sites and sponsors on how to enhance communication and collaboration. Tune in ...
Welcome to Innovating Clinical Trials, the podcast designed for clinical research professionals eager to deepen their understanding of clinical trials through concise, insightful segments. Join your hosts, Liam Eves and Ted Trafford, as they uncover the core issues in clinical research, reflect on the industry, and challenge conventional wisdom. In today's episode, Liam throws a tough question at Ted ... You have been tasked with transforming the enrolment process…the catch? You can only ma...
Welcome to Innovating Clinical Trials, the podcast where Liam and Ted explore the evolving landscape of clinical research and challenge the assumptions holding it back. In this episode, we sit down with Maya Zlatanova — CEO of TrialHub and FindMeCure, and host of Trials with Maya Z — for a no-nonsense look at one of the most misunderstood concepts in research: feasibility. Episode Overview: Maya takes us deep into the hidden layers of clinical trial feasibility, arguing that what most of the ...
Welcome to the Innovating Clinical Trials podcast, where we explore the evolving landscape of clinical research. In this episode, hosts Liam Eves and Ted Trafford sit down with Jill Pellegrino, CEO of AutoCruitment, to explore the future of patient enrollment in clinical trials. With a background spanning leadership roles at CVS Health, PPD, and Accelerated Enrollment Solutions, Jill brings deep expertise in leveraging technology and data-driven strategies to improve recruitment efficiency. J...
Welcome to the Innovating Clinical Trials podcast, where we explore the evolving landscape of clinical research. In this episode, hosts Liam Eves and Ted Trafford continue the conversation with clinical trial feasibility expert Nick Palumbo to examine why feasibility is much more than just site selection—and how rethinking the process can drive better enrollment and study success. Nick shares his insights on the broader role of feasibility, from protocol optimization to enrollment modeling, a...
Welcome to the Innovating Clinical Trials podcast, where we explore the evolving landscape of clinical research. In this episode, hosts Liam Eves and Ted Trafford continue the conversation with clinical research expert Nick Palumbo, diving into the role of data, digital tools, and human expertise in clinical trial feasibility and patient recruitment. Nick shares his insights on the increasing reliance on data-driven approaches for enrollment forecasting and site selection, while also highligh...
Welcome to the Innovating Clinical Trials podcast, where we explore the evolving landscape of clinical research. In this episode, hosts Liam Eves and Ted Trafford sit down with clinical research expert Nick Palumbo to unpack the challenges and opportunities in the feasibility process. Nick brings over two decades of experience in clinical operations, offering deep insights into sponsors, CROs, and research sites when it comes to feasibility assessments. From the burden of feasibility question...
Innovating Clinical Trials Podcast Series: Part 3 - Opportunities in Patient Recruitment and Industry Transformation Welcome to Innovating Clinical Trials podcast, where we explore the cutting-edge shifts in clinical research. In this episode, hosts Liam Eves and Ted Trafford wrap up the series with industry analyst Joel White, diving into opportunities in patient recruitment, site network growth, and the evolving role of technology. Joel shares his insights on breaking down the root causes o...
Innovating Clinical Trials Podcast Series: Part 2 - Pricing Strategies and Emerging Dynamics Welcome to Innovating Clinical Trials podcast, where we continue to explore the rapidly evolving landscape of clinical research. In part 2, hosts Liam Eves and Ted Trafford are joined once again by industry analyst Joel White to dive into the complexities of pricing strategies and the shifting dynamics in the CRO and biotech sectors. This episode unpacks the implications of pricing pressures, the role...
Part 1 - Navigating Trends in a Shifting Landscape Welcome to Innovating Clinical Trials podcast, where we explore the dynamic forces shaping the clinical research industry. In this episode, hosts Liam Eves and Ted Trafford are joined by industry analyst Joel White to unpack the key trends defining Q3. From cancellations and funding challenges to site network innovations and advancements in technology, Joel provides a compelling analysis of the current CRO and biotech landscape—and what the f...
In this episode of Innovating Clinical Trials, Liam Eves and Ted Trafford explore the challenges of recruitment and enrollment in clinical trials, comparing the current approach to "packing everything but the kitchen sink." They critique the overreliance on central advertising campaigns and highlight missed opportunities to address foundational issues like protocol design, site relationships, and storytelling. Ted advocates for simplifying protocols and creating a dedicated VP of Enrollment r...
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