big bets and bad calls

What if you could inhale your vaccine instead of bracing for a needle? We sat down with Dr. Anushi Rajapaksa, founder of Misti, who's on a mission to change the way biological medicines — including vaccines — get into your body. No needle. No clinic. Just a smart inhaler that uses sound waves, from the comfort of your own home

Most psychologists who work with entrepreneurs have studied the experience. Byron has lived it.Before becoming a psychologist, Byron was a venture-backed founder, navigating the pressure, the uncertainty, and the internal chaos that comes with building something from scratch. That experience is what eventually led him to specialise in exactly this space.Byron founded Sublime Studio as a psychological coaching practice built specifically for entrepreneurs. His work centres on what he believes is the real lever in any business: the mind running it. Clarity under pressure, genuine resilience, and the ability to challenge your own thinking — these aren't soft skills. They're the foundation everything else is built on.Alongside one-on-one work with founders, Byron partners with accelerators, universities, innovation hubs, and investment firms — including MAP, the University of Melbourne, Imperial Enterprise Lab, and THRIVE Global — delivering workshops and Psychologist-in-Residence support to founders at every stage.

Most people think "mental load" means remembering to buy milk and book the dentist.Sociologist Leah Ruppanner Ruppaner says that's just the tip of the iceberg — and she's written the book to prove it.In Drained, Leah maps out eight distinct types of mental load that people carry, from emotional support and relationship upkeep, to dream-building for others, to the invisible work of keeping everyone safe and connected.None of it shows up on a to-do list. All of it is exhausting.In our conversation we dig into why people end up carrying so much of this weight, what it actually costs them, and the practical audit she's developed to help people recalibrate, without the guilt.

We sit down with QuarterZip co-founder Andrew Pankevicius, as he takes us on his journey from multiple startups, exits, and pivots, and what the future holds for onboarding at enterprise scale

Today’s guest is Dr Nicole Jenkins co-founder of FeBI Technologies, a deep-tech startup developing quantum sensing technology designed to prevent missed and misdiagnosed iron disorders. It’s a fascinating mix of cutting-edge science and real-world healthcare impact.