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Peptide of the Week | Weight Loss, Health & Wellness

Peptide of the Week | Weight Loss, Health & Wellness

Author: Peptide of the Week| Weight Loss, Health & Wellness

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Hosted by JD Denham and Will Haas, The Peptide of the Week Podcast is your no-BS guide to peptides, peptide therapy, weight loss, longevity, anti-aging, muscle growth, recovery, and total body optimization. Whether you're curious about GLP-1 medications, peptide research, fat loss, building muscle, improving athletic performance, or simply looking for ways to feel better, move better, and live stronger, this podcast breaks down the science in a way everyday listeners can understand.

JD and Will dive deep into the world of peptide science, health optimization, metabolic health, hormone health, fitness, nutrition, and performance enhancement, exploring popular topics like BPC-157, TB-500, GHK-Cu, HGH, and emerging peptide research. From potential benefits and side effects to real-world experiences, safety concerns, and the latest developments in peptide research, they separate the hype from the science.

With expert guests, honest conversations, and hard-earned lessons, each episode explores peptide protocols, weight management, healthy aging, strength training, muscle recovery, fat loss, wellness, and longevity strategies. Whether you're an athlete, fitness enthusiast, biohacker, or beginner interested in learning more about peptides, JD and Will bring you straightforward discussions about the science, risks, and possibilities of optimizing your health.

No fluff. No filters. Just real conversations about peptides, fitness, longevity, and taking control of your health.

Become a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.
142 Episodes
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Follow us on social media:JD's Socials: https://hoo.be/jddenhamofficialWill's Socials: https://hoo.be/williamthaasPeptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcastJoin The Community: https://www.skool.com/peptideresearchinstitute/aboutSubscribe to our Newsletter: https://potwnewsletter.beehiiv.com/Warrior Coaching: https://www.warrior-makerscoaching.comPeptide Of The Week Website: https://peptideoftheweekpod.comMedical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.Part two with Michael Farber goes deep on FLGR-242, the long acting myostatin inhibitor he invented that is helping people gain 10 to 12 pounds of lean muscle in three to four months, without anabolics, without side effects, and regardless of genetics. This is one of the most important muscle building conversations we have ever had on this podcast.🔬 Topics Covered:• Why Farber invented FLGR-242 after losing 2+ years of muscle during COVID• What myostatin actually is and why it is your body's brake on muscle growth and fat burning• Belgian blue cows, super mice, and real world examples of myostatin mutations• Why naturally gifted athletes often have partial myostatin mutations and do not even know it• How FLGR-242 levels the playing field for people not born with athletic genetics• Expected results: 10 to 12 pounds of lean muscle in 3 to 4 months at 5mg per week• Why going above 10mg per week produces virtually no additional gains• Farber personally went to 20mg per week and confirmed no negative health effects above 10mg• How FLGR-242 was designed to bind ONLY myostatin and why that makes it so safe• Why Follistatin-344 causes random growth and must be injected locally while FLGR-242 freely circulates• Brian Johnson's myostatin experiment in Honduras: 2% gain in a year at $50,000 per try• FLGR-242 vs circular DNA myostatin inhibitors: not even close• Apelin-13: the ergogenic compound that optimizes fat burning and cardiovascular output simultaneously• Long acting Thymosin Alpha-1 and Thymosin Beta coming soon• Bioline: the new appetite and metabolism compound coming down the pipeline• The albumin binder platform and why it is changing how every compound performsChapters:00:00 – Intro00:09 – Welcome Back & Will's Mom Moving to Town01:24 – Appreciating Your Parents While You Have Them03:29 – Round Two With Michael Farber: Why He Created FLGR-24206:27 – Myostatin Inhibition Beyond Muscle: Obesity & Fetal Growth10:02 – Leveling the Playing Field for Natural Athletes12:21 – Real-World Results: 10–12 Pounds of Lean Muscle in 4 Months14:44 – Dosing: Why More Than 10 mg a Week Doesn't Help19:23 – How FLGR-242 Differs From Follistatin 34424:06 – Safety Record & Gene Therapy Alternatives27:55 – What's Next: Apelin, Long-Acting Thymosin & Obesity Compounds30:16 – The Albumin Binder Discovery: MC4R & Amylin Compounds34:34 – Cancer Drug Trojan Horse Idea36:40 – Upcoming Launches: Appetite Control & Long-Acting Thymosin Alpha-138:44 – OutroBecome a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.
Follow us on social media:JD's Instagram: https://www.instagram.com/jddenhamofficial/ Will's Instagram: https://www.instagram.com/williamthaas/Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast Join The Community: https://www.skool.com/peptideresearchinstitute/about Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/ Warrior Coaching: https://www.warrior-makerscoaching.com Peptide Of The Week Website: https://peptideoftheweekpod.com Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. JD Denham is live from Maui on his honeymoon while William T. Haas holds it down in the studio. This week they go deep on growth hormone in all its forms covering HGH timing for normal vs reduced pituitary function, whether stacking Tesamorelin on top of HGH is a waste of money, how to run your first steroid cycle properly, why FLGR 242 is the first compound JD says can genuinely compete with gear, and what carpal tunnel symptoms after adding Ipamorelin actually mean. 🔬 Topics Covered• Why taking HGH at night could be silently sabotaging your biggest natural growth hormone pulse• Is stacking Tesamorelin on top of HGH a waste of money or does it still do something unique?• Carpal tunnel and joint pain after adding Ipamorelin at only 200mcg: bad sign or great sign?• Running your first steroid cycle with Test and Primo: why stopping at 8 weeks is the worst mistake you can make• Should you add FLGR 242 or IGF-1 LR3 to a steroid cycle and what actually happens when you do? • Why taking HGH on workout days only and skipping rest days is completely backwards• MK-677 vs Ipamorelin: why one will make you eat everything in sight and the other probably won't affect your hunger at all• Can you stack HGH, MK-677 and IGF-1 LR3 together or is that just overkill?• Why Klotho may be the most underrated compound for anyone running gear and what it is actually doing for your kidneys• Every single person listening should be taking glutathione and here is exactly why Chapters:00:00 – Intro00:09 – Welcome Back & Live From Maui01:49 – Why Vacation and Rest Matter03:20 – How Muscle Actually Grows: Recovery & HGH Timing04:58 – Training Intensity, Dorian Yates & Muscle Group Splits11:12 – Steroids Don't Replace Hard Work13:49 – Why Legs, Back & Deadlifts Matter17:10 – China Trip & Shoutout to the Team18:35 – Buying a Whole American Wagyu Cow22:01 – Q&A: HGH vs. Secretagogues for a 34-Year-Old Woman28:46 – Q&A: Ipamorelin Carpal Tunnel & Joint Pain34:19 – Q&A: Stacking HGH With Tesa, Ipa & Sermorelin41:35 – Q&A: Peptides While Running Test & Primo56:10 – Q&A: HGH, MK-677 & IGF-1 LR3 Timing1:03:11 – Q&A Format Feedback, Skool & OutroBecome a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.
Follow us on social media: JD's Socials: https://hoo.be/jddenhamofficial Will's Socials: https://hoo.be/williamthaas Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast Join The Community: https://www.skool.com/peptideresearchinstitute/aboutSubscribe to our Newsletter: https://potwnewsletter.beehiiv.com/Warrior Coaching: https://www.warrior-makerscoaching.comPeptide Of The Week Website: https://peptideoftheweekpod.comMedical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.This is not a conversation about peptides. This is a conversation with the man who invented two of the most talked about longevity compounds on the planet. Dr. Michael Farber joins JD Denham and William T. Haas to break down Klotho and FLGR-242 from the ground up. Who created them, why he created them, how they actually work in the body, and where medicine is heading in the next 20 years. 🔬 Topics Covered:• Who is Dr. Michael Farber and his 35 years in biochemistry and 150 patents• Why he invented Klotho to save his own kidney after losing his right kidney in his teens• How Klotho regulates phosphate and calcium and why that matters for kidney function• The feedback loop of kidney disease that has never been reversible until now• People going from an EGFR of 40 back up to 70 and beyond on Klotho• Why Klotho makes NAD work dramatically better through the SIRT1 pathway• Klotho and the blood brain barrier: clearing toxic plaque buildup without entering the brain• Why Dr. Farber considers Klotho more important for longevity than FLGR-242• How the albumin binder platform works and why it allows bi-weekly dosing• Klotho dosing: 10 micrograms every two weeks for healthy individuals, every 11 to 12 days for kidney dysfunction• What happens if you overdose Klotho and why it is strictly range-bound• FLGR-242: the long-acting myostatin inhibitor that is outperforming all expectations• Why FLGR-242 dosing is nothing like Follistatin-344 and must not be confused• The future of medicine: synthetic organs, CRISPR, fetal genetic optimization, and living to 120• Dr. Farber consumed a bottle of painkillers a week for decades. In the last 18 months he has taken two or three total.Chapters:00:00 – Cold Open: Living With Kidney Disease for 40 Years00:45 – Intro00:54 – Welcome Back & Meeting Dr. Michael Farber02:50 – Why He Created Klotho: Losing a Kidney05:10 – Klotho Results: 10 mcg & Rising eGFR07:34 – The Albumin Binder Breakthrough12:28 – How Klotho Works in the Body14:53 – Klotho, NAD+ & FLGR-242 Synergy20:13 – Cardiovascular Health & Restored Libido21:54 – Klotho Dosing: 10 mcg Every 11–14 Days24:52 – Separating Hype From Reality27:14 – Overdose Risks & Checking Urine Output29:42 – Feeling "Reborn": Life After Kidney Disease36:30 – The Future of Longevity: Organs & CRISPR45:12 – Outro & Part 2 PreviewBecome a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.
Follow us on social media: JD's Instagram: https://www.instagram.com/jddenhamofficial/ Will's Instagram: https://www.instagram.com/williamthaas/ Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast Join The Community: https://www.skool.com/peptideresearchinstitute/about Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/ Warrior Coaching: https://www.warrior-makerscoaching.com Peptide Of The Week Website: https://peptideoftheweekpod.com Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. JD Denham and William T. Haas sit down for a focused all-R episode covering the most common questions they get about "R". From whether you actually need to stop between cycles, to building a stack from scratch as a brand new female, to using R with breast cancer history, to whether Cagrilintide is worth bridging with over the holidays. Plus Dr. Mike Farber, creator of FLGR 242 and Klotho, is coming on the podcast next week and JD has been running FLGR long enough to say it is giving gear a serious run for its money. 🔬 Topics Covered • Do your R receptors actually burn out and do you need to cycle off?• The best way to time your R doses around the weekend when cravings hit hardest  Building a peptide stack from absolute zero as a 33-year-old female athlete• Why taking too many peptides at once is costing you money and answers• Hormone breast cancer history on R: what is safe and what is not• Why fatigue on R almost always comes down to one thing nobody wants to hear• AOD vs Tesamorelin vs HGH for a 45-year-old male trying to lose his last 20 pounds• Does 5-Amino-1-MQ actually block NAD or is that completely backwards?• The cognitive and fat burning stack for a 40-year-old Marine on TRT and R• FLGR 242 is the first peptide JD says is genuinely giving gear a run for its moneyChapters:00:00 – Cold Open: Should You Stop "R"?01:00 – Intro01:09 – Welcome Back & VIP Zoom Call Updates03:44 – Website, Trusted Sources & Coaching Updates04:59 – Upcoming Guest: Dr. Mike Farber (FLGR-242 & Clotho)08:21 – Q&A: Bridging Between "R" Cycles With Cagrilintide15:24 – Q&A: Building a Peptide Stack as a Beginner28:22 – Q&A: Low Energy on Reta After Breast Cancer38:22 – Q&A: AOD-9604 & CJC After Major Weight Loss46:18 – Q&A: Do 5-Amino-1MQ & NAD+ Conflict?51:41 – Outro & Next Episode Preview52:46 – "R" Takeaways RecapBecome a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.
Follow us on social media: JD's Socials: https://hoo.be/jddenhamofficial Will's Socials: https://hoo.be/williamthaas Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcastJoin The Community: https://www.skool.com/peptideresearchinstitute/about Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/ Warrior Coaching: https://www.warrior-makerscoaching.com Peptide Of The Week Website: https://peptideoftheweekpod.com Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. They all live in the same family but they are NOT the same. JD Denham and William T. Haas break down Melanotan 1, Melanotan 2, and PT-141, what makes each one different, the real side effects nobody warns you about, and some stories that will make you think twice about your dosing before a big meeting. 🔬 Topics Covered: • How melanin actually works and why some people tan and others burn• Melanotan 1: the safest of the three, FDA approved as Scenesse for sun-sensitive skin conditions• Why MT1 does not cross into the brain and what that means for side effects • MT1 and psoriasis: real results people are seeing stacked with BPC and TB-500• Melanotan 2: broader spectrum, crosses into the brain, tanning plus arousal plus appetite suppression• Why MT2 causes more flushing, more nausea, and darker freckles than MT1• Spontaneous erections on MT2 and why Will does not sleep well on it• PT-141 discovered as a metabolite of MT2 and why it works on the brain not the blood vessels• Why PT-141 and Cialis together may be overkill but actually makes sense• FDA approval of PT-141 as Vyleesi for low sexual desire in women• Why PT-141 works for both men and women when Cialis does not• JD's wife approved. Real world experience from both of them• Why your hormones must be optimized or none of this works the way it should• Dosing breakdown: MT1, MT2, and PT-141 injectable and nasal spray• Why you do NOT take any of these before a first date or an important meeting• When to stop because your friends are telling you that you look purple Chapters: 00:00 – Cold Open: PT-141 Stories01:21 – Intro01:30 – Welcome Back & Mold Recovery Update 03:28 – Upcoming Guest Dr. Mike Farber & New Peptides06:16 – Live VIP Workout & Bicep Measuring Contest07:46 – Carnivore vs. Carbs & Upcoming Gear Episode09:56 – Searching Every Peptide Mention on the Website10:57 – Social Media Bans & Industry Camaraderie14:24 – Today’s Compounds: The Melanotan Family15:05 – Melanotan 1: How It Tans23:42 – Melanotan 2: Tan, Libido & Appetite29:49 – PT-141: Arousal, Marriage & Women38:10 – Dosing, Mixing & Nasal Sprays42:04 – Outro, VIP Calls & Live WorkoutBecome a supporter of this podcast: https://www.spreaker.com/podcast/peptide-of-the-week-weight-loss-health-wellness--7447107/support.
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