The Human Upgrade with Dave Asprey

Have we finally discovered the key to youthful energy, longevity, and cellular health? In this episode, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer at Timeline Nutrition and a leading expert on mitochondrial health, cellular regeneration, and anti-aging science. With over 20 years of research, 50 clinical trials, and 15 patents under his belt, Dr. Singh unpacks the groundbreaking science behind Urolithin A, a revolutionary postbiotic that boosts mitochondrial function, enhances immune system resilience, and combats chronic inflammation. This episode goes beyond cutting-edge science. Dr. Singh reveals practical, real-world strategies to combat “inflammaging”—the chronic, low-grade inflammation that accelerates aging. Learn how fasting, gut health, and mitochondrial boosters like Urolithin A can rejuvenate your cells, fight fatigue, and supercharge your energy, vitality, and longevity. Here’s what you’ll learn in this episode:  • What Urolithin A is and its role in mitochondrial health and cellular energy production  • How to reverse “inflammaging” and reduce inflammation through nutrition, fasting, and biohacking  • The connection between mitochondrial dysfunction and immune system aging  • Real-life benefits of Urolithin A for energy levels, athletic recovery, skin health, and longevity  • Why mitochondrial support is critical for combating aging and improving overall performance  Resources:   • 2025 Biohacking Conference – https://biohackingconference.com/2025   • Timeline Nutrition -  https://www.timeline.com/dave to get 10% off your first order   • Timeline Instagram – https://www.instagram.com/timeline_longevity/   • Dave Asprey’s Website – https://daveasprey.com   • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books   • Danger Coffee – https://dangercoffee.com   • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/   • Dave Asprey’s Linktree – https://linktr.ee/daveasprey   • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com   • Own an Upgrade Labs – https://ownanupgradelabs.com   • Upgrade Labs – https://upgradelabs.com   • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com  Timestamps:  • 00:00 Introduction to Longevity and Mitochondria  • 01:28 The Role of Mitochondria in Immune Health  • 03:36 Understanding Inflammaging and Immune Aging  • 07:47 Measuring Immune Health and Inflammation  • 13:33 Urolithin A: A Mitochondrial Booster  • 16:46 Dosage and Effects of Urolithin A  • 26:11 Urolithin A and Exercise Performance  • 28:31 Urolithin A for Skin Health  • 31:34 Collagen and Aging: The Role of MMPs  • 33:27 Personal Experience with MMPs and Recovery  • 35:04 Measuring MMPs and Their Impact on Longevity  • 36:18 Skin Health and Urolithin A  • 38:39 Exploring Urolithin A’s Broader Benefits  • 40:33 Brain Health and Urolithin A  • 43:33 Combining Supplements for Optimal Health  • 45:54 Omega-3s and Mitochondrial Health  • 46:51 Ketones, MCTs, and Urolithin A  • 54:30 Final Thoughts on MitoPure and Supplementation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Are exosomes the planet’s ultimate healing tool?! In this episode, Dave Asprey sits down with Harvard-trained physician Dr. Edward Park to explore the groundbreaking science of exosomes. Dr. Park, a pioneer in regenerative medicine and author of Exosomes: Songs of Healing, explains how these tiny cellular messengers are revolutionizing health and longevity by bypassing the limitations of stem cells. BUT this episode isn’t just about cutting-edge science. Dr. Park also shares profound insights into life, resilience, and emotional well-being, offering advice that goes far beyond medicine. From the power of forgiveness to breaking free of limiting beliefs, his perspective blends science, spirituality, and practical wisdom for living a better life. Here’s what you’ll learn in this episode:  • How exosomes work and why they’re being called the future of regenerative medicine  • The key differences between exosomes and stem cells—and which is better for healing  • Real-life applications of exosome therapy for injuries, anti-aging, and overall health  • The potential of exosomes to enhance brain function, reduce inflammation, and promote recovery  • Dr. Park’s advice on emotional resilience, gratitude, and creating lasting change With over a decade of experience, Dr. Park shares compelling case studies, cutting-edge insights, and practical advice for anyone looking to upgrade their body, mind, and life. Whether you’re managing chronic pain, exploring anti-aging therapies, or seeking wisdom for navigating life’s challenges, this episode has something for everyone. Sponsors TRU KAVA | Go to https://trukava.com and enter code DAVE15 at checkout for 15% off  Resources: • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Dr. Edward Park’s Website: Recharge Biomedical – https://www.rechargebiomedical.com • Dr. Edward Park’s Book: Exosomes: Songs of Healing – https://www.amazon.com/EXOSOMES-Songs-Healing-Ed-Park/dp/098260632X • Dr. Edward Park’s YouTube Channel – https://www.youtube.com/channel/UCpp9DlRArB1rKAWNwoouiTg • Dr. Edward Park on Instagram – https://www.instagram.com/dredpark/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com  Timestamps:  • 00:00 Introduction to Exosomes and Healing  • 00:48 Understanding Exosomes: Stem Cell Communication  • 01:19 Dr. Edward Park’s Insights on Exosomes  • 02:47 Exosomes vs. Traditional Treatments  • 04:44 Exosomes in Regenerative Medicine  • 07:33 Cost-Effective Regeneration Protocols  • 12:35 Exosomes for Hair Growth  • 14:37 Stem Cells and Brain Health  • 25:33 Banking Stem Cells for Future Use  • 35:27 Epigenetic Age and Longevity Predictors  • 37:48 CRISPR and Gene Editing: Risks and Benefits  • 39:43 Basic Health Tips for Longevity  • 41:02 Spirituality, Past Lives, and Healing  • 42:50 Questioning Medical and Political Narratives  • 47:54 The Importance of Free Speech  • 01:07:40 The Role of Intuition in Medicine  • 01:09:22 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is biohacking your sweat the secret to vitality? Dave Asprey dives into the transformative world of infrared saunas with Connie Zack, founder of Sunlighten and a 25-year innovator in the space. Together, they uncover how targeted light and heat therapy can unlock unparalleled health benefits, from detoxing heavy metals to energizing your body at the cellular level. Here’s what you’ll learn in this episode: • Why infrared saunas excel at detoxing heavy metals and toxins • How they mimic exercise to boost cardiovascular health and recovery • The science behind infrared’s impact on mitochondrial energy and longevity • Surprising benefits for gut health, inflammation, and hormone balance • Hacks to get the most out of your infrared sauna sessions Connie shares cutting-edge research and personal insights, offering practical ways to integrate infrared therapy into your routine. Whether you’re looking to recover faster, improve your mood, or support long-term health, this episode delivers the tools you need to take your biohacking game to the next level. Special Offer: Use code “DAVE” at sunlighten.com to get up to $1,000 off until December 6th! Sponsors:-ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. -fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources: • Sunlighten Saunas Website – https://www.sunlighten.com/dave/?utm_source=DaveAsprey&utm_medium=Partner&utm_content=Podcast&leadsource=DaveAsprey&utm_campaign=DaveAsprey • Sunlighten Saunas on Instagram – https://www.instagram.com/sunlightensaunas/    • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps  • 00:00 Introduction to Infrared Saunas • 00:27 Meet Connie Zack: Leading Voice in Infrared Saunas • 00:50 The Science Behind Infrared Saunas • 02:35 Infrared Saunas vs. Traditional Saunas • 05:41 Health Benefits of Infrared Saunas • 08:14 Technological Advancements in Infrared Saunas • 17:36 The Role of LEDs in Infrared Saunas • 22:37 Practical Tips and Personal Experiences • 28:14 Detoxing and Energizing with Glutathione • 28:40 Pre and Post-Sauna Rituals • 29:05 Habit Stacking in the Sauna • 29:41 Managing Overheating Devices • 31:05 Creative Breakthroughs in the Sauna • 32:14 Scientific Method and Personal Experience • 36:05 Understanding Glucose Spikes • 38:44 Longevity Benefits of Infrared Saunas • 43:27 Infrared Saunas and Skin Health • 45:29 Extreme Detox Protocols • 48:28 Grip Strength and Longevity • 50:34 Customizing Your Sauna Experience See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if you could command any room and set boundaries without saying a word? Dave Asprey sits down with Kasia Urbaniak, founder and CEO of The Academy—a trailblazing school where women learn the true principles of influence and authority. Kasia brings a unique and dynamic perspective, drawing on nearly two decades of experience that includes working as a professional Dominatrix, practicing Taoist alchemy in one of China’s oldest female-led monasteries, and earning certifications across disciplines like Medical Qi Gong and Systemic Constellations. Here’s what you’ll learn in this episode: • How to set clear, unbreakable boundaries in any situation • Techniques for wielding influence without sacrificing integrity • Tools to reclaim inner authority and navigate life with confidence • Practical strategies for handling power dynamics in relationships, work, and beyond Kasia’s methods have empowered over 4,000 women worldwide to step into leadership roles in every sphere, from personal relationships to professional arenas. In this episode, she shares practical insights on transforming how you’re perceived by others and, more importantly, how you perceive yourself. Whether you’re navigating complex workplace dynamics, strengthening personal boundaries, or seeking clarity in relationships, Kasia’s teachings offer a path to reclaiming the powerful, authentic authority within you. Sponsors -Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.  -LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/dave.  Resources: • 2025 Biohacking Conference – https://biohackingconference.com/2025 • Kasia Urbaniak’s Website – https://www.kasiaurbaniak.com • Kasia Urbaniak’s Book: Unbound: A Woman’s Guide to Power – https://www.kasiaurbaniak.com/unbound • The Academy – Practical Training for Women on Power and Influence – https://www.kasiaurbaniak.com/the-academy • Kasia Urbaniak on Instagram – https://www.instagram.com/kasiaurbaniak/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps: • 00:00 Introduction to the Human Upgrade • 01:07 Meet Kasia Urbaniak: Author of Unbound • 02:52 Exploring Power Dynamics • 04:46 The Role of Emotions in Power • 14:50 Embodiment and Somatic Work • 32:58 The Power of Voice and Presence • 48:22 Collective Intelligence and Intuition • 54:50 Facing Fears and Intuition • 55:15 Male vs. Female Intuition • 56:01 The Power of Erotic Energy • 57:13 Welcoming Emotions and States • 59:10 Role-Playing and Personas • 01:00:06 Teaching Women to Speak Up • 01:02:04 Energetic Dynamics in Relationships • 01:04:35 Victimhood and Healing • 01:19:54 The Power of Asking • 01:29:40 Money and Emotional Alchemy • 01:31:53 Shameless Money Conversations • 01:44:00 Final Thoughts and Upcoming Events See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is unlocking the full potential of your brain even possible, or just a myth from the movie Limitless? In this eye-opening episode, neuroscientist and author Dr. Mithu Storoni joins Dave to dive deep into the science of brain optimization for hyper-efficient work performance. Together, they break down the surprising roles of astrocytes in supporting neurons, the influence of the brain’s “blue dot” region (the locus coeruleus) on focus and mental clarity, and how harnessing neuroplasticity can lead to improved cognitive efficiency and resilience in high-stress environments. Get ready to discover actionable science-backed hacks for enhancing work productivity and maintaining focus—even in the face of constant distractions. Dr. Storoni also explains how optimizing your breathing rhythm, managing your brain’s arousal state, and tapping into the natural flow of ultradian rhythms can dramatically improve your mental output. Whether you’re looking to elevate your workflow, supercharge your mental performance, or unlock the science of hyper-efficiency, this episode delivers essential strategies to cultivate a high-performing mind for work and beyond. Tune in to understand how the latest neuroscience can transform how you think, focus, and excel every day. Sponsors -Quantum Upgrade | Go to Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Resources: • Dr. Mithu Storoni’s Website – https://www.mithustoroni.com • Hyper Efficient: Optimize Your Brain to Transform the Way You Work by Dr. Mithu Storoni – https://www.hachettebookgroup.com/titles/mithu-storoni/hyperefficient/9780316566933/ • Dr. Mithu Storoni on Facebook – https://www.facebook.com/drmithustoroni/ • Dr. Mithu Storoni’s LinkedIn – https://www.linkedin.com/in/mithu-storoni-0488872a/ • Dave Asprey’s Website – https://daveasprey.com • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps • 00:00 – Introduction to Brain Complexity • 00:29 – The Human Upgrade with Dave Asprey • 01:42 – Meet Dr. Mijtu Storoni • 02:16 – Understanding Brain Efficiency • 02:57 – The Role of Astrocytes • 04:37 – Brain Adaptability and Environment • 06:55 – Biohacking and Environmental Signals • 08:34 – Power vs. Efficiency Debate • 11:26 – The Importance of Glial Cells • 18:10 – The Brain as a Predictive Machine • 23:14 – Nutrition and Brain Health • 32:33 – The Gut-Brain Connection • 36:36 – Eye Health as a Proxy for Brain Health • 40:47 – Aligning the Brain: The Blue Dot Network • 41:54 – Understanding Brain Gears and Stress Management • 42:27 – Maintaining the Goldilocks Zone for Optimal Brain Function • 43:09 – The Role of Creativity and Daydreaming • 44:28 – Strategies to Stay in Optimal Mental States • 47:44 – Biohacking for Enhanced Efficiency • 51:00 – The Science Behind Flow States • 57:09 – Harnessing Innate Curiosity for Mental Efficiency • 01:03:46 – Breathing Techniques for Mental Regulation • 01:13:32 – The Importance of Ultradian Rhythms • 01:17:40 – Practical Tips for Efficient Breaks • 01:21:20 – Conclusion: Embracing Hyper Efficiency See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if the keys to an extraordinary life lie in choices most people wouldn’t dare to make? In this iconic, unearthed episode, best-selling author and performance pioneer Tim Ferriss joins Dave Asprey to spill the unfiltered truth on smart drugs, insect protein, and the surprising links between sex, creativity, and high performance. They dig into cutting-edge topics still sparking curiosity today: the calculated risks and rewards of smart drugs, the future-forward benefits of insect protein, and how unconventional habits fuel creativity and peak performance. Tim candidly shares his personal protocols, from routine blood testing to strategic supplementation, all rooted in his philosophy that “the dose makes the poison.” As a powerful wrap-up, Tim lays out his top three life principles for real success: choosing high-caliber people, focusing on those who “get it,” and setting audacious, even wild, goals. Whether you’re biohacking or simply intrigued, this episode delivers timeless insights and bold ideas for anyone ready to unlock a high-performance life. Sponsors -Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.  -Pendulum | Go to https://pendulumlife.com/ and use code Asprey20 for your first month of GLP-1 or any Pendulum formula. Resources:  • Tim Ferriss’ Website – https://tim.blog  • Tim Ferriss’ Book Club – http://fourhourbook.club/  • Tim Ferriss’ Podcast – https://tim.blog/podcast/  • Dave Asprey’s Website – https://daveasprey.com  • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books  • Danger Coffee – https://dangercoffee.com  • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/  • Dave Asprey’s Linktree – https://linktr.ee/daveasprey  • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com  • Own an Upgrade Labs – https://ownanupgradelabs.com  • Upgrade Labs – https://upgradelabs.com  • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com Timestamps  • 00:00 Introduction to Early Episodes  • 00:57 The Human Upgrade with Tim Ferriss  • 01:58 Smart Drugs and Their Effects  • 05:09 Experimenting with Health and Performance  • 13:53 The Role of Creativity and Writing  • 17:05 Exploring Nutrition and Insect Protein  • 21:01 Handling Criticism and Audience Responsibility  • 30:04 Sex, Performance, and Longevity  • 33:21 Tim Ferriss’ Top Three Life Tips   See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if everything you believe about happiness is wrong? In this episode, Harvard professor and world-renowned happiness expert Arthur Brooks joins Dave Asprey to unlock the secrets of real happiness, revealing the science behind joy, resilience, and lasting fulfillment. As a bestselling author and co-author with Oprah Winfrey of Build the Life You Want, Arthur has spent decades helping people rethink happiness through a blend of psychology, neuroscience, and ancient wisdom. Together, Dave and Arthur explore eye-opening topics like the “reverse bucket list,” why dopamine-driven goals often lead to disappointment, and how embracing discomfort can actually create deeper contentment. Arthur dives into why our common pursuits of fame, wealth, and success often fall short, and shares powerful strategies for mastering what’s within our control, building resilience, and finding meaning in life’s simplest moments. From managing dopamine to harnessing the power of small wins, this episode offers science-backed insights and practical tools to elevate your life with lasting joy and purpose. If you’re ready to transform your approach to happiness, tune in for strategies that truly work.  Sponsors Leela Quantum | Head to https://leelaq.com/DAVE for 10% off. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. Resources:  • Arthur Brooks’ Website – https://arthurbrooks.com  • Arthur Brooks’ TED Talk: A New Way to Think About Happiness – https://www.ted.com/talks/arthur_brooks_the_art_and_science_of_happiness?subtitle=en&geo=es • Arthur Brooks’ Weekly Column: How to Build a Life in The Atlantic – https://www.theatlantic.com/author/arthur-c-brooks/  • Dave Asprey’s Website – https://daveasprey.com  • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books  • Danger Coffee – https://dangercoffee.com  • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/  • Dave Asprey’s Linktree – https://linktr.ee/daveasprey  • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com  • Own an Upgrade Labs – https://ownanupgradelabs.com  • Upgrade Labs – https://upgradelabs.com  • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com    Timestamps • 00:00 – Introduction to Reverse Bucket List • 00:35 – The Science of Happiness • 00:58 – Personal Journey to Happiness • 01:44 – Meet Arthur Brooks • 04:26 – The Role of Music in Emotions • 07:43 – Understanding Emotions and the Brain • 09:50 – Parenting and Influence • 18:06 – Public Speaking and Performance • 34:10 – Striving for Success and Happiness • 39:40 – The Struggle with Body Image and Nutrition • 40:03 – Reverse Bucket List: Assessing Attachments • 40:57 – The Science of Dopamine and Motivation • 43:09 – The Dangers of Pornography and Dopamine • 44:03 – Biohacking and Pain Management • 47:03 – The Importance of Small Wins • 48:48 – Embracing Pain and Discomfort • 53:01 – The Role of Pain in Personal Growth • 56:12 – The Concept of Non-Resistance • 57:17 – The Happiness of Strivers • 01:01:13 – The Importance of Relationships and Spiritual Life • 01:03:22 – The Role of Fame and Legacy • 01:16:31 – The Value of Truthfulness and Compassion • 01:17:59 – Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Explore the science and potential of hypnosis as Dr. David Spiegel, Stanford’s leading expert in mind-body medicine, joins Dave Asprey to reveal how hypnosis can radically enhance cognition, mental clarity, and resilience. In this episode of The Human Upgrade, you’ll learn how hypnosis influences the brain’s most vital networks, including the default mode network and executive control, to break mental barriers and amplify focus, perception, and healing. Discover how hypnosis, unlike traditional meditation or neurofeedback, accelerates response times, manages pain, and even helps alleviate PTSD. Dr. Spiegel shares stories of patients overcoming chronic pain and trauma through self-hypnosis, and details the mechanisms that make hypnosis a powerful tool for emotional and physical transformation. Dive into the fascinating brain science behind the practice, from theta brainwave induction to deep sensory modulation, and learn simple self-hypnosis techniques that can elevate mental performance, improve sleep quality, and instill lasting calm. If you’re seeking a powerful, accessible way to biohack your brain and harness the potential of your mind, this episode delivers the insights and tools you need to make hypnosis your ultimate cognitive upgrade.   Sponsors Quantum Upgrade | Go to Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Resources: • Dr. David Spiegel’s Website – https://med.stanford.edu/profiles/david-spiegel • Reveri Hypnosis App – https://reveri.com (available on App Store and Google Play) • Dave Asprey’s Website – https://daveasprey.com • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement https://40yearsofzen.com Timestamps • 00:00 – Introduction to Hypnosis • 00:59 – Dave Asprey Introduces Dr. David Spiegel • 02:03 – Dr. Spiegel’s Journey into Hypnotherapy • 06:06 – The Power of Hypnosis in Medical Practice • 11:19 – Understanding Hypnosis and Brain Function • 16:14 – Hypnosis for PTSD and Trauma • 19:33 – Hypnosis vs. EMDR: Key Differences • 22:30 – Pain Management through Hypnosis • 31:06 – The Impact of Psychedelics on Cancer Patients • 33:04 – Exploring Psychedelic-Assisted Neurofeedback • 34:05 – Neuroimaging and Brain Activity in Hypnosis • 35:22 – Hypnosis and Cognitive Enhancement • 38:53 – Hypnosis for Sleep and Stress Management • 42:26 – Hypnosis and the “Manchurian Candidate” Concept • 48:21 – Hypnosis and the Immune System • 53:11 – Live Hypnosis Session with Dave Asprey • 58:46 – Conclusion and Final Thoughts  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Unlock the mastermind secrets to cognitive enhancement as Dave Asprey shares his ultimate brain-boosting biohacks in this powerful episode of The Human Upgrade. Discover how Dave elevated his IQ, reversed Asperger’s, and overcame brain fog through advanced neurofeedback, BDNF-boosting supplements, mitochondrial enhancers, and the power of the groundbreaking 40 Years of Zen program. Explore revolutionary techniques, from ancient meditation practices to modern nootropics and smart drugs, all designed to amplify memory, focus, and resilience. Learn the science behind cognitive enhancement, from ketones like C8 MCT oil to essential supplements like Vitamins D, K, A, and magnesium that fuel optimal brain function. If you’re seeking proven methods to enhance neuroplasticity, boost mental endurance, or reduce brain fog, this episode is packed with actionable insights. Whether you’re aiming to maximize mental performance or unlock the latest in brain science, Dave’s mastermind approach offers a comprehensive guide to upgrading your mind and achieving peak potential. Prepare to boost cognitive abilities, harness your mind’s true power, and achieve new levels of clarity with Dave’s most effective brain and body biohacks—culminating in the transformative experience of 40 Years of Zen. Sponsors40 Years of Zen | Neurofeedback training for advanced cognitive enhancement https://40yearsofzen.com/upgrade/Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.Pendulum | Go to https://pendulumlife.com/ and use code Asprey20 for your first month of GLP-1 or any Pendulum formula.Resources: • Dave Asprey’s Website – https://daveasprey.com • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.com • Mendi Neurofeedback Device – Home neurofeedback device for attention and focus improvement https://www.mendi.io • Ketone IQ by HVMN – Go to https://ketone.com/dave for 30% off your first subscription of Ketone IQ.• Qualia NAD – Support for mitochondrial function and cellular energy https://qualialife.com/dave (use code DAVE for discounts) • Vitamin DAKE – Fat-soluble vitamin complex designed by Dave Asprey https://vitamindake.com • Minerals 101 – Comprehensive mineral supplement for cognitive and metabolic support https://shopsuppgradelabs.com/products/minerals-101  Timestamps: • 00:00 Intro • 00:32 Introduction to Cognitive Enhancement • 01:41 Dave’s Personal Journey and Struggles • 04:15 Discovering Cognitive Enhancement Tools • 11:36 Exploring Neurofeedback and Brain Training • 14:22 The Power of Mitochondria and Neuroplasticity • 23:45 Supplements for Cognitive Enhancement • 32:33 The Role of NAD+ in Brain Function • 34:41 Foundational Supplements for Brain Health • 36:17 Essential Supplements for Cognitive Function • 37:29 The Importance of Magnesium and Zinc • 39:14 Meditation and Breath Work for Brain Health • 40:07 Avoiding Toxins for Better Brain Function • 42:56 The Impact of EMFs on Brain Health • 46:25 Neurofeedback and Cognitive Enhancement • 01:05:01 The Power of Ketamine in Neurofeedback • 01:09:49 Final Thoughts and Recommendations • 01:09:49 Testimonials  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Unlock the secret to cellular detox and discover how to cleanse your body from the inside out with Dave Asprey and Jessica Berman in this episode of The Human Upgrade. Explore cutting-edge detox strategies using phosphatidylcholine, Tudca, and butyrate, three powerful molecules designed to remove toxins, microplastics, and endocrine disruptors from your system. Jessica, co-owner of BodyBio, reveals how these products support not just detoxification, but also optimize mitochondrial function, enhance brain performance, and improve overall cellular health. From phosphatidylcholine’s ability to restore cell membranes to Tudca’s role in liver health, you’ll learn how to protect yourself from the daily onslaught of environmental toxins that can harm your longevity and vitality. If you’ve been searching for how to reduce your toxic load, flush out microplastics, or boost cognitive function, this episode is packed with actionable insights. Whether you’re a biohacker looking to enhance your cellular resilience or someone curious about how these supplements can improve your overall health, this episode will take your detox game to the next level. Get ready to learn how to detox like a pro, rebuild your cell membranes, and optimize your brain and body with these game-changing biohacks! Resources:  • BodyBio Phosphatidylcholine, Tudca, Butyrate & More – Get 25% off BodyBio products with code DAVEASPREY https://bodybio.com/collections/dave-asprey?affluencerId=Dave%20Asprey&linkId=Dave%20Asprey_Clear%20It%20All_Podcast• Dave Asprey’s Website – https://daveasprey.com • The Human Upgrade Podcast – https://daveasprey.com/category/podcasts/ • Danger Coffee – https://dangercoffee.com • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ • Dave Asprey’s Linktree – https://linktr.ee/daveasprey • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com • Own an Upgrade Labs – https://ownanupgradelabs.com • Upgrade Labs – https://upgradelabs.comTimestamps: • 00:00 Intro • 00:30 Introduction and Importance of Grass-Fed Barbecue • 01:03 The Ubiquity of Environmental Toxins • 01:39 Minimizing Exposure and Detoxification • 02:47 Introducing Jessica Berman and BodyBio • 04:41 Understanding Cell Membranes • 08:55 Phosphatidylcholine and Its Benefits • 27:54 Clinical Observations and Future Research • 36:49 The Reality of Modern Toxins • 37:00 Understanding Lipophoric Toxins • 37:44 Detoxification Strategies • 38:30 The Role of Phospholipids • 39:16 Liver Health and Detox • 40:29 The Benefits of Tudca • 41:24 Choline and Fatty Liver • 42:20 Debunking TMAO Myths • 44:28 Soy Lecithin vs. Sunflower Lecithin • 47:21 Mitochondrial Health and Prenatal Care • 50:03 Biohacking for Healthy Aging • 55:35 The Importance of Phospholipids for Cognitive Health • 59:12 Mold Toxins and Health • 01:01:45 Building Resilient Humans • 01:05:02 Exclusive Offer for Listeners See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Step into the future of sports performance with The Human Upgrade as Dave Asprey and Aron D’Souza, founder of the Enhanced Games, uncover the controversial world of steroids, gene therapy, peptides, and human enhancement. In this groundbreaking episode, they explore how athletes can push the boundaries of physical and mental performance by embracing cutting-edge science once banned by traditional sports bodies like the Olympics. Discover why the Enhanced Games are redefining fairness in athletics, allowing competitors to use biohacking and performance-enhancing technologies to unlock new levels of strength, speed, and recovery. Aron breaks down the ethical dilemmas, the science behind enhancements, and why athletes should have full control over their bodies and biology. From synthetic growth hormones to the latest in gene therapy, this episode dives deep into the future of sports innovation. Whether you’re fascinated by the world of biohacking, curious about the next big revolution in sports, or want to understand how gene therapy and performance enhancers could impact human longevity, this episode delivers a thought-provoking look into the possibilities of superhuman performance. Could you be the world’s next super athlete? Age might soon be irrelevant! The future of athletic potential is wide open—are you ready to take the leap? Sponsors: Omni-Biotic | Visit omnibioticlife.com/dave and use code DAVE20 for 20% off. Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide.  Resources:  • Enhanced Games – https://enhanced.org  • Enhanced Games Instagram – https://www.instagram.com/enhanced_games/  • Dave Asprey’s Website – https://daveasprey.com  • The Human Upgrade Podcast – https://daveasprey.com/category/podcasts/  • Gene Therapy for Longevity – https://daveasprey.com/genetherapy  • Danger Coffee – https://dangercoffee.com  • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/  • Dave Asprey’s Linktree – https://linktr.ee/daveasprey  • Dave Asprey’s Book Smarter Not Harder – https://daveasprey.com/books  • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com  • Own an Upgrade Labs – https://ownanupgradelabs.com  • Upgrade Labs – https://upgradelabs.com Timestamps:  • 00:00 – The Toxic Belief System  • 00:31 – Introduction to the Human Upgrade  • 02:42 – The Enhanced Games Concept  • 04:12 – Olympic Inequality and Corruption  • 05:19 – The Case for Performance Enhancements  • 10:54 – Transparency and Financial Incentives  • 15:30 – Health and Safety in Enhanced Games  • 18:14 – Global Impact and Future of Enhanced Games  • 25:28 – Cognitive vs. Physical Enhancements  • 28:54 – Historical Context and Future Vision  • 33:54 – Human Enhancements and Banned Substances  • 34:36 – The Enhanced Games: Concept and Vision  • 35:53 – Biohacking and Cognitive Enhancers  • 36:24 – The Birth of the Enhanced Games  • 37:00 – Data and the Future of Sports  • 40:20 – Criticism and Scientific Debate  • 42:03 – Ethics and Sponsorship  • 47:55 – Gender and Competition Categories  • 54:41 – Funding and Logistics of the Enhanced Games  • 57:06 – The Future of Sports and Human Potential  • 57:46 – Technological and Engineered Enhancements  • 01:04:16 – Getting Involved and Final Thoughts  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Unlock the power of continuous glucose monitoring (CGM) and transform your health in this eye-opening episode with Dave Asprey. Discover why tracking your blood sugar 24/7 isn’t just for diabetics—it’s the key to unlocking peak health, optimizing your metabolism, and preventing chronic diseases. Joined by Levels founder and biohacker Josh Clemente, Dave dives into the real science behind CGMs and how they provide unparalleled insights into how your diet, sleep, and exercise affect your blood glucose. You’ll learn how glucose spikes are linked to aging, inflammation, and energy crashes, and why keeping your blood sugar stable can help you boost mental clarity, enhance longevity, and even prevent conditions like diabetes and heart disease. Josh reveals the engineering mindset behind building Levels and how this game-changing technology is revolutionizing the way we understand metabolic health. With insider data from 50,000+ users, you’ll discover how simple lifestyle tweaks—like post-meal walks, sleep optimization, and personalized nutrition—can dramatically improve your health outcomes. This episode is a must-listen for anyone serious about biohacking, metabolic control, and optimizing every aspect of their health through real-time data. Learn how to take control of your body and get ahead of the game in the future of health monitoring. Sponsors: Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. OneSkin | Go to https://oneskin.co/ and use code ASPREY15 for 15% off your purchase.  Resources: • Levels: Visit https://levels.link/daveasprey to get two extra months of membership with Levels. • Levels Instagram: https://www.instagram.com/levels • Josh Clemente Instagram: https://www.instagram.com/joshuasforrest • Dave Asprey’s Linktree: https://linktr.ee/daveasprey • Dave Asprey’s Book Smarter Not Harder: https://daveasprey.com/books • Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ • Upgrade Collective: Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com • Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps: • 00:00 - Introduction to Personal Data Rights • 00:38 - The Importance of Blood Sugar Monitoring • 01:16 - Dave Asprey’s Journey with Glucose Monitoring • 02:47 - The Evolution of Continuous Glucose Monitors • 03:31 - Installing the New Levels Sensor • 04:39 - The Role of Data in Biohacking • 05:47 - From SpaceX to Glucose Monitoring • 09:49 - The Need for Better Health Data • 13:25 - The Intersection of Engineering and Health • 20:25 - The Future of Personalized Health Data • 28:46 - The Impact of Continuous Glucose Monitoring • 35:45 - Levels’ Research and Findings • 40:28 - Understanding Food Logging and Blood Sugar Response • 41:14 - The Struggle with Weight Loss and Willpower • 41:56 - The Role of Different Foods in Blood Sugar Management • 44:32 - Biohacking and Personalized Nutrition • 49:30 - The Impact of Sleep on Blood Sugar Control • 55:23 - The Future of Health Monitoring and AI • 59:19 - Practical Tips for Blood Sugar Management • 01:02:01 - The Importance of Tracking Health Metrics • 01:15:35 - Blood Sugar and Cognitive Function • 01:21:01 - Final Thoughts and Recommendations   See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Get ready to discover the true superfoods that can transform your health—starting with spirulina and chlorella. In this dynamic and thought-provoking episode, Dave Asprey welcomes Catharine Arnston, founder of ENERGYbits, to dive deep into the world of algae and its incredible potential to boost energy, detox the body, and support longevity. First, we challenge the myths around trendy “superfoods” and reveal why algae, particularly spirulina and chlorella, reign supreme for mitochondrial health and cellular energy. Catharine shares her 15 years of research on algae, explaining how it protects your cells, enhances brain function, and even supports cancer prevention. Next, we explore cutting-edge science on how algae supercharge mitochondrial performance, with Catharine revealing new clinical trial data that shows a 20% boost in mitochondrial function in just seven days. Finally, we break down the real-life impacts—improved brainpower, glowing skin, and detoxified cells—showing how this powerhouse algae can revolutionize the way you think about your health. This episode will change the way you approach superfoods and biohacking forever. Resources: ENERGYBits: Visit energybits.com and use code UPGRADE for 20% off your order. ENERGYbits Instagram: https://www.instagram.com/energybits/ Dave Asprey’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book Smarter Not Harder: https://daveasprey.com/books Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Join The Human Upgrade Podcast Live – Upgrade Collective: https://www.ourupgradecollective.com Own an Upgrade Labs: https://ownanupgradelabs.com  Timestamps:  • 00:00 – You Won’t Believe This  • 00:39 – Introduction to Superfoods  • 01:24 – The Benefits of Algae  • 02:20 – Guest Introduction: Catharine Arnston  • 03:19 – Catharine’s Journey to Algae  • 04:16 – The Science Behind Algae  • 05:22 – Mitochondria and Algae  • 05:53 – The Role of Superoxide Dismutase (SOD)  • 06:24 – Alkaline Diets and Health  • 22:20 – Phycocyanin: The Cancer-Fighting Pigment  • 29:52 – Clinical Trials and Future Research  • 31:31 – Spirulina Efficacy Study  • 32:12 – Mitochondrial Health Insights  • 32:56 – Intermittent Fasting vs. Spirulina  • 35:27 – Testimonials and Real-Life Benefits  • 39:52 – Quality Control and Safety  • 43:31 – Skin Health and Algae  • 47:34 – Dosing and Usage Tips  • 48:18 – Brain Health and Recovery  • 50:57 – Aging and Biohacking  • 53:39 – Final Thoughts and Offers See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we’re diving into the age old question, what is the purpose of your life? We chat about the science behind emotional intelligence with Dr. John Demartini, creator of the groundbreaking Demartini Method. In this thought-provoking episode, Dr. Demartini reveals how his unique approach to personal development and emotional mastery can help you uncover your highest values and transcend emotional chaos. We explore how the quality of the questions you ask shapes the quality of your life, providing a roadmap to unlock your fullest potential. First, we dig into the hidden order of the universe, showing how the Demartini Method guides you to balance emotion, intuition, and inspiration for greater control and fulfillment in life. Then, we break down Dr. Demartini’s journey—overcoming learning challenges, mastering the mind-body connection, and developing a method that has transformed lives around the globe. Finally, Dr. Demartini shares actionable strategies for tapping into your innate brilliance, balancing your values, and discovering the magnificence already within you. This episode will shift your perspective on personal growth, purpose, and the power of self-awareness. Sponsors: ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.  Quantum Upgrade | Go to Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial.  Resources: Dr. John Demartini’s Website: https://drdemartini.com/ Dr. John Demartini’s Instagram: www.instagram.com/drjohndemartini Dr. John Demartini’s YouTube: www.youtube.com/c/drdemartini Dave Asprey’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com Join The Human Upgrade Podcast Live – Upgrade Collective: https://www.ourupgradecollective.com Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps and Highlights: • 00:00 - Introduction to Dr. John Demartini • 01:56 - The Demartini Method Explained • 04:53 - Delegating and Managing Stress • 08:19 - Journey to Mastery and Overcoming Challenges • 15:08 - The Power of Reading and Learning • 22:57 - Transforming Education in South Africa • 28:39 - Integration of Knowledge and Universal Principles • 34:23 - Understanding Emotions and Intuition • 35:09 - The Role of Intuition in Awareness • 35:41 - Inspiration and Full Consciousness • 37:31 - The Hidden Order in the Universe • 40:17 - The Concept of Divine Guidance • 45:52 - The Neuroscience of Divine Order • 54:56 - The Demartini Method and Human Behavior • 59:18 - Applying the Demartini Method • 01:05:00 - The Breakthrough Experience • 01:07:49 - Final Thoughts and Gratitude See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we’re unlocking the full potential of your brain—starting with Bryan Johnson’s Blueprint for longevity and brain optimization. We’re revisiting our conversation with Bryan, the creator of the Don’t Die movement (among many other things), to explore how his groundbreaking approach to brain health and biohacking is reshaping the future of longevity. First, we dive into Bryan’s mission to make brain monitoring as easy as tracking blood glucose, using his Blueprint protocol to measure and optimize cognitive performance for better health and wellness. Then, we tackle the deeper side of biohacking—longevity, societal reactions to living longer, and how to handle critics when you’re pushing the limits of human potential. Finally, Bryan shares his personal journey—investing $80M into brain science, building the Blueprint for optimal living, and discovering the power of community and lifelong friendships for a long, vibrant life. This episode will change the way you think about brain health and the future of humanity. Sponsors: Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order. Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Resources: Bryan Johnson’s Blueprint Protocol: https://blueprint.bryanjohnson.com/ Bryan Johnson’s Don’t Die Movement: https://dontdie.bryanjohnson.com/ Bryan Johnson’s Kernel: https://www.kernel.com/ Bryan Johnson’s YouTube Channel: https://www.youtube.com/@bryanjohnson_ Bryan Johnson’s Instagram: https://www.instagram.com/bryan_johnson_ Dave Asprey’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com Join The Human Upgrade Podcast Live – Upgrade Collective: https://www.ourupgradecollective.com Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps and Highlights: 00:00 Introduction and Bold Claims 00:39 Meet Bryan Johnson: The Neuroscience Pioneer 01:23 Kernel: Revolutionizing Brain Measurement 05:51 Biohacking and Longevity 07:30 Facing Criticism and Staying Resilient 16:06 Media Training Insights 19:49 Personal Reflections and Relationships 34:37 Exercise and Longevity 44:46 Optimizing Brain-Body Interface 45:25 Longevity Hacks and Driving Preferences 45:48 Debating Olive Oil and Saturated Fats 46:52 The Blueprint Approach to Health 48:38 Testing and Metrics in Health 52:22 Testosterone and Hormone Protocols 56:27 Exploring Semen Retention 01:00:44 Body Hair and Aesthetics 01:04:26 Psychedelics and Consciousness 01:08:32 Audience Q&A and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we’re diving deep into biohacking your body’s performance—starting with your VO2 max and mitochondria. We’re sitting down with cellular optimization expert, Rowena Gates, to dive into how the NanoVi device is disrupting the world of biohacking, recovery, and training. First up, we’re breaking down VO2 max—the secret sauce to longevity. Forget endless hours of cardio. Learn how to hack your VO2 max efficiently and add years to your life, without grinding it out in the gym. Then, we tackle the hidden world of reactive oxygen species (ROS). These little molecules can be both your friend and foe—boosting energy or fast-tracking aging. We’ll show you how to control them, so you can keep your energy levels high and your body youthful. Finally, we explore the cutting-edge science of protein folding and exclusion zone water. Sound complicated? Don’t worry, we’ll break it down and show how NanoVi tech supercharges your mitochondria, giving you faster recovery and more endurance, all with minimal effort. Sponsors: Eng3 Special Offer Code: https://eng3corp.com/dave/ Resources: Rowena Gates’ Website: https://www.eng3corp.com NanoVi Device: https://www.eng3corp.com/nanoviRowena Gates’ LinkedIn: https://www.linkedin.com/in/rowenagates/ Dave Asprey’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com Join The Human Upgrade Podcast Live – Upgrade Collective: https://www.ourupgradecollective.com Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps and Highlights: 00:00 Introduction to Metabolic Health 00:38 The Importance of VO2 Max 02:34 Reactive Oxygen Species Explained 05:57 The Role of Water in Cellular Health 14:11 Mitochondrial Function and Longevity 20:25 Cognitive Function and Biohacking 21:45 Advanced Meditation and Mitochondria 22:09 Post-Exercise Recovery Insights 22:37 NanoVi and Athletic Performance 23:42 Pro Athletes and Biohacking 27:00 Mitochondrial Function and Health 33:24 NAD and Cellular Health 36:29 Biohacking for Modern Living 37:48 Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today, we’re hacking your home—big time. I’m sitting down with three experts who know exactly how your living space might be messing with your health, and more importantly, how to fix it. First up, we’ve got Michael Rubino, aka the mold medic, who’s here to blow your mind about the invisible toxins lurking in your walls. Mold? It’s everywhere, and it’s doing more damage than you think. Michael’s got killer insights on why dust might be your biggest health enemy and exactly how to get rid of it before it starts messing with your system. Then, we’ve got Ryan Blaser dropping some serious science on environmental toxins you probably didn’t even know were impacting you. EMFs? VOCs? Ryan explains why your home’s air quality might be worse than you think, and how to fix it with a few smart biohacks. Finally, Matteo Franceschetti, the sleep optimization guru, breaks down how your home could be trashing your sleep. He’s got the secrets to transforming your environment so you can supercharge your recovery and performance every night. Check out the Full Episodes here:  • Detox Your Home: How to Improve Indoor Air Quality & Get Rid of Mold – Michael Rubino | 1036 https://www.youtube.com/watch?v=gncPqFlRXho&t=2s • How Mold Affects Your Health & What You Can Do About It – Michael Rubino | 1041 https://www.youtube.com/watch?v=QD5RUcN8uds&t=2s • Improve Your Home Environment & Breathe Better – Michael Rubino | 1045 https://www.youtube.com/watch?v=gncPqFlRXho&t=2s Sponsors: Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide. Calroy | Head to https://calroy.com/dave for an exclusive discount.  Resources: Michael Rubino’s Website: https://www.themoldmedic.com Michael Rubino’s Instagram: https://www.instagram.com/mold_medics/Michael Rubino’s Book: https://www.themoldmedic.com/books Michael Rubino’s Company: https://www.allamericanrestoration.com Ryan Blaser’s Website: https://www.testmyhome.com Ryan Blaser’s Instagram: https://www.instagram.com/testmyhome/Ryan Blaser’s Blog: https://www.testmyhome.com/blog Matteo Franceschetti’s Website: https://www.eightsleep.com Matteo Franceschetti’s Instagram: https://www.instagram.com/matteofranceschetti Eight Sleep Instagram: https://www.instagram.com/eightsleepDave’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com Own an Upgrade Labs: https://ownanupgradelabs.com Timestamps and Highlights: 00:00 Introduction: The Hidden Dangers in Your Home 00:02 Air Quality and Mold: The Silent Threat 00:40 Furniture Choices for Better Air Quality 01:51 Cleaning and Maintenance Tips 03:00 The Impact of Environmental Toxins 04:04 Formaldehyde and VOCs: Invisible Enemies 07:36 Energy Efficiency vs. Health 11:14 HVAC Systems and Air Filters 21:57 DIY Dust Testing and Home Lab Kits 29:02 Top Indoor Pollutants and Final Thoughts 30:47 Identifying Mold in Your Home 31:46 Health Impacts of Mold Exposure 32:18 Dangers of Air Fresheners and Fragrances 33:23 Improving Indoor Air Quality 35:59 Gas vs. Electric Stoves 37:07 Lighting and Its Effects on Health 40:57 Managing Humidity and Mold in Humid Climates 43:17 Carbon Monoxide: The Silent Killer 46:26 Dealing with VOCs in Your Home 50:38 Importance of Regular Cleaning 52:26 Noise Pollution and Its Impact 53:41 Advanced Sleep Tracking Technology 59:04 The Future of Consumer and Medical Devices  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if you could control your brain’s performance and stress levels with just a few simple hacks? In this episode callback, Dave Asprey sits down with Dr. Andrew Huberman, a renowned neuroscientist from Stanford University, to unlock the secrets of how your brain really works—and how you can train it for enhanced cognitive power and stress resilience. From rewiring your brain’s fear response to mastering your level of alertness, Dr. Huberman reveals groundbreaking discoveries that could change the way you approach your mental and emotional well-being. Diving deep into neuroscience, they cover how visual stimuli can modulate stress, the role of autonomic arousal in cognitive performance, and even how brain-machine interfaces may soon push human potential beyond its current limits. You’ll learn why certain visual and sensory techniques can calm or excite your brain, and how to train your brain to handle high-stress situations with ease. Plus, find out how Dr. Huberman is working on curing blindness with VR technology—offering a glimpse into the future of human augmentation. Sponsors:  Apollo Neuro | Head to https://apolloneuro.com/DaveAsprey to save 15% on an Apollo wearable.Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.Resources: Dr. Andrew Huberman’s Stanford Profile: https://profiles.stanford.edu/andrew-huberman Huberman Lab Podcast: https://hubermanlab.com/podcast Follow Dr. Andrew Huberman on Instagram: https://www.instagram.com/hubermanlab Dave’s Linktree: linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’: daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/    Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/  Supplements by Dave Asprey: https://shopsuppgradelabs.com/  Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights:   • 00:00 — Introduction and Cool Fact of the Day • 00:07 — Understanding Anxiety Through Brain Activity • 02:07 — Meet Dr. Andrew Huberman • 03:33 — The Five Components of Life Experience • 05:29 — Autonomic Arousal and Cognitive Performance • 08:00 — Visual Stimuli and Stress Management • 10:22 — Exploring Fear and Courage in Mice • 15:17 — Human Applications and VR Experiments • 23:10 — The Role of Vision in Autonomic Arousal • 29:38 — Bridging Neuroscience and Wellness • 30:43 — Curing Blindness: A Personal Mission • 34:50 — VR Goggles and Visual Stimulation • 35:12 — The Power of Virtual Art Galleries • 35:58 — Exploring Neuroplasticity in Adults • 38:31 — Potential and Risks of VR Technology • 40:27 — Human Augmentation and Neuroscience • 43:22 — Brain-Machine Interfaces and Non-Invasive Techniques • 45:47 — The Evolution of Biohacking • 52:03 — Personal Biohacking Journeys • 56:34 — Longevity and Life Extension • 59:28 — Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Get ready to upgrade your cardiovascular health in a way you’ve never heard of before. Dave Asprey sits down with Dr. Michael Twyman, a pioneering biohacking cardiologist who blends cutting-edge functional medicine with conventional wisdom to help you avoid heart attacks and strokes. If you think cardiovascular disease is inevitable, think again. Dr. Twyman reveals the hidden mechanisms behind heart disease, starting with the misunderstood role of plaque in your arteries and the essential yet underappreciated glycocalyx—a slippery gel-like coating that could be the key to preventing arterial damage. From there, it’s all about prevention, prevention, prevention. Want to know how simple lifestyle tweaks can significantly reduce your risk of cardiovascular events? We’ve got the biohacks—grounding, sunlight exposure, cold plunges, and more—laid out for you in a step-by-step, easy-to-apply format. Dr. Twyman breaks down the crucial role of circadian biology and how aligning your body clock with natural light cycles can help protect your heart. Plus, learn why grounding might just be the ultimate, free anti-inflammatory tool you’ve been missing. This episode isn’t just about tips and tricks—it’s a complete roadmap to understanding and optimizing your heart health. Dave and Dr. Twyman get into the nitty-gritty of lab tests you should be asking for, why exercise is only part of the solution, and how the current medical insurance model fails to protect your cardiovascular future. Don’t miss out on these life-saving insights that are rooted in both ancient wisdom and modern science.  Sponsors:  Viome | Go to https://viome.com/dave to save $110 on the Full Body Intelligence Test. fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. Resources: Calroy Health Sciences: https://calroy.com/ Dr. Michael Twyman’s Website: https://www.apollocardiology.com/ Follow Dr. Michael Twyman on Instagram: https://www.instagram.com/drtwyman Dave’s Linktree: linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’: daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/    Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/  Supplements by Dave Asprey: https://shopsuppgradelabs.com/  Own an Upgrade Labs: https://ownanupgradelabs.com/ Timestamps and Highlights: • 00:00 — Introduction to Cardiovascular Health • 01:22 — Meet Dr. Michael Twyman • 05:57 — Understanding Heart Attacks • 08:09 — The Role of Glycocalyx in Cardiovascular Health • 15:17 — Lifestyle Changes for Cardiovascular Health • 24:32 — Exercise and Cardiovascular Health • 27:58 — Effective VO2 Max Strategies • 28:12 — Patient Exercise Goals and Time Management • 29:12 — Thyroid and Cardiovascular Health • 32:49 — Circadian Biology and Heart Disease • 33:57 — Sunlight, Grounding, and Seasonal Health • 38:49 — The Role of Statins in Cardiovascular Health • 43:16 — Key Labs for Cardiovascular Risk Assessment • 50:33 — Insurance and Preventative Health • 54:35 — Conclusion and Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Are you sleeping enough—or just enough to get by? In this episode of The Human Upgrade, Dave Asprey dives into the global sleep crisis and reveals why mastering your sleep is the most important biohack you can do for your health, performance, and longevity. This episode is your ultimate guide to transforming your rest and, by extension, your life. First, sleep scientist Matthew Walker breaks down how sleep deprivation has become a global epidemic, slashing up to 20% of our sleep in the past century. He unpacks the dangers of too little sleep, including its direct link to increased mortality rates and cognitive decline, and discusses the optimal sleep duration for both quantity and quality. Next, Peter Martone shifts the conversation to sleep posture and environment. He shares simple yet effective techniques for optimizing your sleep position to maximize deep, restorative rest. Learn how a small change in your pillow or bed setup can lead to dramatic improvements in your sleep quality and overall health. Finally, Dan Gartenberg dives into the world of sleep biohacking. He reveals groundbreaking research on how sound waves can enhance your deep sleep and how controlling light exposure can unlock better rest. From sleep-tracking tech to environmental optimizations, Dan provides actionable tips to help you take your sleep game to the next level. By the end of this episode, you’ll walk away with expert-backed strategies, biohacking secrets, and sleep science insights that will completely transform the way you sleep—and live. Check out the Full Episodes here:  - Sleep is the Boss of You – Matthew Walker, Ph D | 616 https://www.youtube.com/watch?v=cxmtBy0YQjs - Change Your Body Position To Get Better Sleep with Dr. Peter Martone | 819 https://www.youtube.com/watch?v=RKhA3iclRK0 - Sleep Need & Sleep Age Find Out Yours – Dan Gartenberg | 583 https://www.youtube.com/watch?v=XbxB67M-s2A Sponsors: Leela Quantum | Head to https://leelaq.com/DAVE for 10% off. ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.  Resources: Matthew Walker’s Website: https://www.sleepdiplomat.com Matthew Walker’s Instagram: https://www.instagram.com/drmattwalker/ Matthew Walker’s Podcast: https://themattwalkerpodcast.buzzsprout.com Matthew Walker’s Book: https://www.amazon.com/Why-We-Sleep-Unlocking-Dreams/dp/1501144316 Peter Martone’s Website: https://www.necknest.com Peter Martone’s Instagram: https://www.instagram.com/peter.martone/ Peter Martone’s YouTube Channel: https://www.youtube.com/user/drpetemartone Peter Martone’s Facebook Group: https://www.facebook.com/groups/necknest Dan Gartenberg’s Website: https://www.sonicsleepcoach.com Dan Gartenberg’s Instagram: https://www.instagram.com/drdansgarden/ Dan Gartenberg’s App: https://www.sonicsleepcoach.com Dan Gartenberg’s TED Talk: https://www.ted.com/speakers/dan_gartenberg Dave’s Linktree: https://linktr.ee/daveasprey Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/ Supplements by Dave Asprey: https://shopsuppgradelabs.com Own an Upgrade Labs: https://ownanupgradelabs.com  Timestamps and Highlights: 00:00 Introduction: The ROI on Sleep 00:24 Global Sleep Loss Epidemic 01:43 Sleep Duration and Mortality Risk 06:23 The Importance of REM Sleep 12:47 Optimizing Sleep Quality 17:37 Technological Interventions for Better Sleep 19:02 Temperature Regulation and Sleep 21:03 Light's Impact on Sleep 24:44 Personal Sleep Hacks and Experiments 33:40 Understanding Lymphatic and Glymphatic Drainage 34:42 Debunking Side Sleeping Myths 35:30 The Importance of Cervical Alignment 37:07 Improving Sleep Quality with Neck Nest 38:00 Audience Questions: TMJ and Sleep 41:07 The Impact of Food and Temperature on Sleep 45:28 Enhancing Sleep with Sound and Technology 01:01:08 The Role of Cortisol in Sleep Quality See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.