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You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.
Become a Paid Subscriber: https://anchor.fm/dr-daniel-j-guerra/subscribe
You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.
1161 Episodes
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Professor Guerra begins an arc of lectures on the molecular events that describe the covalent modification and temporal variation of gene expression collectively called epigenetics.
T Lymphocyte communication with antigen presenting innate immune cells coupled with B cell activation may be regulated by a glycoprotein that links to discrete glycosylation patterns on membrane polypeptide domains
In this Authentic Biochemistry episode Dr Guerra unfolds the complex transcription factor and membrane & nuclear- receptor repertoire associated cytokine and chemokine axis activating and maintaining Treg cell differentiation to mediate the Th pro- inflammatory response
This is the first part of a diaeventontological framing of lipid peroxidative mechanisms for CNS neurodegeneration. Dr Guerra describes recent published research (JLR 2018 .59:312pp.) and develops some of the key elements of the ferroptosis programmed cell death mechanism leading to oligodendrocyte and neuronal degeneration that will participate in a grander understanding of injury-induced and idiotypic age-associated disease in the CNS. 25 March 2019.
In this podcast, Dr Daniel Guerra of Authentic Biochemistry and VerEvMed endeavours to examine the bioenergetic and pro-inflammatory prodromal patho-biochemistry of age-onset Alzheimer's Disease using his diaeventontological toolkit.
Dr. Daniel J. Guerra introduces his paradigmatic shift for understanding biochemical phenomena as prolegomena to understanding Alzheimer's Disease.
Dr Daniel Guerra of Authentic Biochemistry in his initial podcast introducing the show and starting off with initial content on current Alzheimer's Disease research
ReferencesFront Pharmacol. 2022 Sep 13;13:1002915.Guerra, DJ. 2026. Unpublished LecturesExperimental & Molecular Medicine 2023. 55, pages 1110–1130 Hunter/Garcia/Weir.1973 Wake of the Flood. Grateful Deadhttps://music.youtube.com/playlist?list=OLAK5uy_lD82hRPMacmRgwRiSljvVgZw-P4Ez7jos&si=vaBkHgV7Y1vk9B3P
ReferencesArch Gerontol Geriatr . 2002 May-Jun;34(3):169-84 Ann Hum Genet. 2025 May;89(2-3):126-131J Inherit Metab Dis. 2025 Jan 17;48(1):e12833Guerra,DJ. 2026. Unpublished Lectures.Beethoven, LV. 1808. Symphony 6 in F. op.68. (Pastorale) https://music.youtube.com/watch?v=xWDIwsfgQnE&si=tPzoONR6d_1d10iMLamm, R.1972. State of the Union Chicago V.https://open.spotify.com/track/3yV42bUfbTp1wIweoUOg22?si=72bbe6c9d2334300
referencesJ Immunol. 2012 Mar 21;188(8):3686–3699. Redox Biol. 2022 Feb 4;50:102257Nature Reviews Molecular Cell2023Biology v 24: 86–106 Nat Cell Biol. 2023 Oct30;25(12):1787–1803J Immunol. 2012 Mar 21;188(8):3686–3699Anderson/Squire/Bruford/Wakeman.1972.Close to the Edge. Yes.https://music.youtube.com/playlist?list=OLAK5uy_lYv_TpuiFzrPaTq69e0eJdT1XLZT2wyTU&si=JHPaYeunwcRtInm4
ReferencesFront Immunol. 2021; 12: 613591Nature Communications2023. volume 14,Article number: 1611 PNAS 2001. vol.98.(5) February 27:2425- 2430Nature Communications 2018.Vol 9, Article number: 3630 McCoy/Minnie and Paige/Plant. 1929/1970 When the Levee Breaks.https://music.youtube.com/watch?v=uwiTs60VoTM&si=5Z5pmI9Has7EHrGpMozart, WA. 1791. Requiem in D Minor K.626https://music.youtube.com/playlist?list=OLAK5uy_nSNY0VtEjG1DYcoE6gg9tibETknwAWeLY&si=senu_gC7gLPsinMa
ReferencesSci Rep. 2025 Aug 23;15:30983Experimental & Molecular Medicine 2019. volume 51, Article number: 80Guerra, DJ.2026. Unpublished LecturesCell Reports 2015 10, 2043-2054DOI:(10.1016/jLennon/McCartney, Harrison. 1965. Rubber Soul lp. Beatleshttps://music.youtube.com/playlist?list=OLAK5uy_lirCIxLpU2odTVLZ_Sbo1wZaeu5IStivs&si=TFDYm-Wh8ks7xGSW
ReferencesInternational Immunopharmacology2024, 112237Volume 134, 15 June Guerra, DJ. 2026 unpublished LecturesTeleman, GP. 1767. Concerto four violins in G Majorhttps://music.youtube.com/watch?v=gtxcH5erQ1E&si=rKLfnaEyDdKedykD
ReferencesCell Death & Disease 2014. volume 5, e1416 J Biomed Sci 2017. 24, 63 Cancer and Metastasis Reviews (2025) 44:16 J Exp Clin Cancer Res2023. 42, 275 (2023)Guerra,DJ.2026.Unpublished LecturesVivaldi, A. 1718. La Primavera in E Major. RV 269. OP 8.https://music.youtube.com/watch?v=3LiztfE1X7E&si=IjC_s5TaQhSMhk4FRogers and Hammerstein. 1945. It might as well be Spring. Frank Sinatra.https://music.youtube.com/watch?v=GzHqGuWFkG8&si=NBYFSV05e3hernpw
ReferencesOncotarget. 2016 Nov 26;7(52):87402–87416Cell. 2021 Mar17;184(7):1790–1803.e17.Guerra, DJ.2026. Unpublished LecturesLennon/McCartney. 1966. Good Day Sunshine Beatles Revolver.https://open.spotify.com/track/7HTH1ppjkkOe7RLoBDKXYJ?si=7dd345d4ea8d4423Jagger/Richards. 1971. Wild Horses. Rolling Stoneshttps://open.spotify.com/track/4M4Q3JLsUbyTkd5WHty1WB?si=b5090e98b840495cLake, G. 1970. Take a Pebble ELP.https://open.spotify.com/track/5eOQRQATdELa16j2AbTE5x?si=d2623c7e807449a8
referencesGuerra, DJ.2026 Unpublished lecturesCell. 2021 Apr 1; 184(7)1790–1803.e17. Nature Cell Biology2022 volume 24, pages 940–953Balin, M. 1968 Volunteers Jefferson Airplanehttps://open.spotify.com/track/7pTL00cPeIGhvVNlq5qP0k?si=f5f42440ca1a4836Idris Davies,1958The Bells of Rhymney.Byrdshttps://open.spotify.com/track/1mpv6hIbfG75txI9zJGcf4?si=2e67db1d289d4b0aSloan. 1965. Eve of Destruction. Barry McQuirehttps://open.spotify.com/track/1Zi2ezNOqt9y9irC11xYpN?si=a291d387ff324313
ReferencesGuerra, DJ. 2026 Unpublished Lecture.Cell. 2021 Apr 1; 184(7):Cell. 2024. Volume 187, Issue 3 p733-749.e16February 01.Nat Immunol. 2018 Jul9;19(8):871–884. Vinson and Chatmon. 1930 Sitting on top of the World. Cream. Wheels of Fire lp.https://open.spotify.com/track/0aY5bJ4jRHiOd8eCMWmcy8?si=a969586b68694b0eLamb, R. 1972. Dialogues I&II Chicagohttps://open.spotify.com/track/02F55MPyLuAUnSSvDg4lP4?si=f9a8d6e6ff0c41e4Pankow,J.1969. Liberation. Chicago Transit Authorityhttps://open.spotify.com/track/385g7dy2YZ1uNV9AJhOpUv?si=b316eef0684e4682
ReferencesNat Immunol. 2018 Jul9;19(8):871–884. J Immunol Res. 2025 Jul17;2025:9328523Biochem Biophys Res Commun. 2024 Mar 12:700:149598.Int J Mol Sci. 2019 Oct; 20(19): 4962.Tempchin, G 1972 Peaceful Easy Feeling. Eagleshttps://music.youtube.com/watch?v=n-0lRkuNyj0&si=7cBHTtUT8_c2yC7xCorelli, A. 1700. Violin Sonata in D Minor. OP 5. No.7https://music.youtube.com/watch?v=uRv44TQTacA&si=fp8rT4JDtFRsD4ij
ReferencesCell. 2021 Apr 1; 184(7):1790–1803.e17Methods Mol Biol. 2022; 2497:129–140. Guerra, DJ.2026. Unpublished LecturesClapton/Bruce/Brown. 1967 Sunshine of your Love Live Cream Vol IIhttps://music.youtube.com/watch?v=tVCeZvusHCU&si=LzcFIKnxe0GP461mHenley/Browne, 1972, Take it Easy Eagleshttps://open.spotify.com/track/4yugZvBYaoREkJKtbG08Qr?si=915e639119db4c91Miller, R. 1962 King of the Roadhttps://open.spotify.com/track/3XG7bMVcMWLIn2k9jLAaAt?si=68578db0407f452f
ReferencesCurr Opin Allergy Clin Immunol 2025, 25:444–454Guerra. DJ.2026. Unpublished Lectures.BiolOpen. 2019 Oct 15; 8(10): bio040311Lennon/McCartney. 1966. Rain. Beatleshttps://open.spotify.com/track/48TNLcToLs8DWkdj5vYdiW?si=375c43203c1c4ccdClapton/Bramlett, 1970. Let it Rainhttps://open.spotify.com/track/7DiaNCPgH5dJ1cJ925jTAA?si=b8bfac43cdef493cPage/Plant. 1973. The Rain Songhttps://open.spotify.com/track/3JLrri1xSCui3bzITDJbkk?si=6c47b7b4a0974806 Townsend, P. 1973. Love, Reign O'er Me. The Whohttps://open.spotify.com/track/4Mqs0h95KAeNiGp7u4udlt?si=56521c6a1b71425aLightfoot, G. 1975. Rainy Day Peoplehttps://open.spotify.com/track/1TZteKaf5z3P3i87jyB8jc?si=def4f81ab3ef4100
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I engage with your episodes with considerable interest and a strong sense of curiosity. Discovering your lectures on Castbox was particularly gratifying. Thank you, Doctor.
listening to episode one from 2019 in which Doctor Guerra was talking about insulin and Alzheimer's disease. I googled it. now 12/12/2025 some are starting to call AD type 3 diabetes. BRAVO DR. DANIEL J. GUERRA!!!! . It seems to me that diabetes screws with everything in the body. . Robert Bristow LVN.