DiscoverAuthentic Biochemistry
Authentic Biochemistry
Claim Ownership

Authentic Biochemistry

Author: Dr Daniel J. Guerra

Subscribed: 68Played: 1,644
Share

Description

Become a Paid Subscriber: https://anchor.fm/dr-daniel-j-guerra/subscribe


Become a Paid Subscriber: https://anchor.fm/dr-daniel-j-guerra/subscribe

You have wisely landed upon Authentic Biochemistry, with Dr. Daniel J Guerra, where published biochemical, physiological, genetic and immunological research along with biomedical and pharmaceutical science are interrogated.
1048 Episodes
Reverse
Professor Guerra begins an arc of lectures on the molecular events that describe the covalent modification and temporal variation of gene expression collectively called epigenetics.
T Lymphocyte communication with antigen presenting innate immune cells coupled with B cell activation may be regulated by a glycoprotein that links to discrete glycosylation patterns on membrane polypeptide domains
In this Authentic Biochemistry episode Dr Guerra unfolds the complex transcription factor and membrane & nuclear- receptor repertoire associated cytokine and chemokine axis activating and maintaining Treg cell differentiation to mediate the Th pro- inflammatory response
This is the first part of a diaeventontological framing of lipid peroxidative mechanisms for CNS neurodegeneration. Dr Guerra describes recent published research  (JLR 2018 .59:312pp.) and develops some of the key elements of the ferroptosis programmed cell death mechanism leading to  oligodendrocyte and neuronal degeneration that will participate in a grander understanding of injury-induced  and idiotypic age-associated disease in the CNS. 25 March 2019.
In this podcast, Dr Daniel Guerra of Authentic Biochemistry and VerEvMed endeavours to examine the  bioenergetic and pro-inflammatory prodromal  patho-biochemistry of age-onset Alzheimer's Disease using his diaeventontological toolkit.
Dr. Daniel J.  Guerra introduces his paradigmatic shift for understanding biochemical phenomena as prolegomena to understanding Alzheimer's Disease.
Dr Daniel Guerra of Authentic Biochemistry in his initial podcast introducing the show and starting off with initial content on current  Alzheimer's Disease research
ReferencesGuerra, DJ. 2025. Unpublished lecturesAm J Physiol Endocrinol Metab.2016 Jul 1; 311(1): E42–E55Front Physiol. 2025 Feb 21;16:1537231.Hunter /Garcia/ et al. 1970. American Beauty full lp.https://music.youtube.com/playlist?list=OLAK5uy_nc3dHmM6xdsySO1SSxYLYzlm82rVZ1pfM&si=iDqjow4NZB320m7dBach, JS. 1730's Ariashttps://music.youtube.com/watch?v=hPWBbvUDMPQ&si=P_-_T4Uy5SsgW9aZ
ReferencesOnco Targets Ther. 2020 Jun 11;13:5429–544Int Immunopharmacol . 2023 Sep:122:110629Fogerty, J. 1971.Have You Ever Seen the Rain? CCRhttps://music.youtube.com/watch?v=u1V8YRJnr4Q&si=9RaKlYclVcAs1XBpBrowne, J 1972. Something Finehttps://music.youtube.com/watch?v=7QYxF2Scjpo&si=SchjtLteEp2-WjKgMozart, WA. 1785. Piano Concerto 21 C major, K. 467 https://music.youtube.com/watch?v=zXHc5sxUMBQ&si=pfIr0LKlQJmJqIs3
ReferencesJ Cell Sci 2018;131:jcs215152Apoptosis. 2024 Jun 17;29(9-10):1309–1329.Guerra, DJ. 2025. Unpublished LecturesSchmelzer, JH. 1664. Violin Sonatashttps://music.youtube.com/playlist?list=OLAK5uy_mddrwq102d1OkVPQUZx7Jtf6oM_ypirro&si=Oy1azNYbKScyYmc0Emerson/Lake/Palmer. 1970. ELP 1st albumhttps://music.youtube.com/playlist?list=OLAK5uy_mv9qs6UUxhvKtYqXufJcbSYcmGatXQjzY&si=IfyZXx-ynBYfwjAG
ReferencesGuerra, DJ. 2025 Unpublished LecturesTrends in Cell Biology, 2024-04-01, 34, Issue 4: 327-337, Signal Transduction and Targeted Therapy 2021. 6, Article number: 49Lennon/McCartney. 1965. Yesterdayhttps://music.youtube.com/watch?v=TQemQRL_YVQ&si=Ma2AwcVOF6TgGfLuRichards/Jagger. 1969. Gimme Shelter. Rolling Stoneshttps://music.youtube.com/watch?v=EJRdDhnTRoo&si=ljhj-NFqc1AV3CEr
ReferencesMolecular Membrane Biology2015. Vol32. Issue4. 21 : 89-116 Nature Reviews Immunology2019.19, pages 273–281Inflammation. 2023 May 4:1–15.White/Lane/Squire/Anderson/ Wakeman/Howe. 1978. You Can Be Saved Yeshttps://music.youtube.com/watch?v=0TNzPHoVlz8&si=YReghaUP5653HlmZDavies, R. 1971 Muswell Hillbilly Kinkshttps://music.youtube.com/watch?v=JodoULnz5cY&si=FlhaAPrEvwMS2Z15
ReferencesGuerra, DJ. 2025. Unpublished LecturesJBC 2016. Volume 291, Issue 8, 19 February:3932-3946Biomarker Res. 2021. volume 9, Article number: 1 Canadian Journal of Cardiology 2025. Volume 41, Issue 9, September:736-1752Hatdn, M. 1757. Violin Concerto in G Major and Concerto for Harpsichord and Viola.https://music.youtube.com/watch?v=WP2vXExDz5k&si=64zQRYANBuYOInZ2 https://youtu.be/rNSuP-3EYV4?si=0dOEGNF0AKxsN9cw
ReferencesExperimental Neurology 2020.Volume 329, July 113310Guerra, DJ. 2025. Unpublished LecturesSimon, P. 1968 Bookends lp.https://music.youtube.com/playlist?list=OLAK5uy_k3-qF40J5ZGpMdUa8bXL4gjfxKQm6UefM&si=_oXZfwyulmodyAftHaydn, FJ. 1765 . Hob V:A2 - String Trio in A majorhttps://music.youtube.com/watch?v=e-ARpkZEZbk&si=YsUwXSWjsBM3YvJO
ReferencesCell. 2014 Jul 3;158(1):41–53. Protein Sci. 2012 Nov 26;22(2):204–212Nature Medicine  2019 volume 25, pages1739–1747 Diabetol Metab Syndr. 2020 Sep 29;12:83Guerra, DJ. 2025. Unpublished LecturesSaint Saens, C. 1886. Carnival of the Animals. R125.https://music.youtube.com/playlist?list=OLAK5uy_lDnzphXFlUHh2Ehihfij0AGtaslto6G-Q&si=PcLZJI8CXXgacbg_Lennon/McCartney. 1963 She Loves Youhttps://music.youtube.com/watch?v=nGbWU8S3vzs&si=Vtt8y5M0DF5Md2btArgent, R. 1967. Time of the Season. Zombieshttps://music.youtube.com/watch?v=RBxK3CcOQD8&si=TxiSN9frf06T-Ldg
ReferencesDiabetol Metab Syndr. 2020 Sep 29; 12:83Obes Sci Pract.2016 Dec 19;3(1):3–14Eur J Endocrinol. 2017 176(5): R235–R246.Winwood/Capaldi. 1972 Low Spark of High Heeled Boys. Traffic.https://music.youtube.com/watch?v=vDGorIWYz-A&si=F7pqWRzuGjaK8WTjVivaldi, A 1720 Autumnhttps://music.youtube.com/watch?v=Z21_VpNipfg&si=OqW9M7Nud4lugMpb
ReferencesJCI Insight. 2016 Nov 17; 1(19): e87748. Front Immunol. 2023; 14: 1149366Adv Biol Regul. 2019 Jan;71:41-54. Diabetol Metab Syndr. 2020 Sep 29;12:83Guerra, DJ 2025 Unpublished lecturesCarroll and Kiley. 1962. The Sweetest Soundshttps://music.youtube.com/watch?v=YWp9cIvzOOs&si=_wGjf4ZSk3shO8NtO'Riordan and Hogan.1992. Dreams The Cranberrieshttps://music.youtube.com/watch?v=SezuFrHm8f0&si=HNrCkouFaX8mLCJcDavies, R. and D. 1971 Skin and Bone. Kinks Muswell Hillbilly LP.https://music.youtube.com/watch?v=0eDMfPWMN-k&si=_BaEfXFJdBEvilVD
References Endocrinology. 2018 Nov 15;160(1):205–219Int J Mol Sci. 2018 Jul 21;19(7):2124International Journal of Biological Macromolecules 2023.Volume 253, Part 5, 31 December. 27042Dylan, B. 1973. Knocking on Heaven's Doorhttps://music.youtube.com/watch?v=z4R5crZylQ0&si=5ZDmgJ4Zh8_h3F9aHunter/Garcia. 1971. Not Fade Away/Goin Down the Roadhttps://music.youtube.com/watch?v=pvcb1mkihho&si=8jR1uuARxBBHssZ-
ReferencesKant, I Critique of Pure Reason. 2nd Edition 1787.Kierkegaard, S. 1849. The Sickness unto Death. Guerra 2025 Notes and thoughts on a Tuesday afternoon. UnpublishedHayward, J and J Lodge. 1967. Tuesday Afternoon. Moody Blues https://music.youtube.com/watch?v=jmMPBQ4kYKk&si=QqYC7kv_gQQw86K2Haydn, FJ. 1794. Symphony 101 in D Major "The Clock" Hob1/101https://music.youtube.com/watch?v=fAfs5Ic0Uwc&si=uHNcXktvM8_mjL_s
ReferencesCells. 2023 Mar 14;12(6):896Arteriosclerosis, Thrombosis, and Vascular Biology 2019. Volume 39, Issue 3, March:432-445Beethoven, LV. 1809. The Emperor Piano Concerto #5. in E flat Major. Op 73.https://music.youtube.com/watch?v=kiW-QnQzN9Y&si=xBR59nceJWhZapjF
loading
Comments