Authentic Biochemistry

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Lecture 1 on General Epigenetics from Dr Guerra of Authentic Biochemistry on 29 October 2019

2019-10-3030:41

Professor Guerra begins an arc of lectures on the molecular events that describe the covalent modification and temporal variation of gene expression collectively called epigenetics.

T lymphocyte mediated auto inflammation from Dr. Guerra's Authentic BIOCHEMISTRY

2019-12-1729:07

T Lymphocyte communication with antigen presenting innate immune cells coupled with B cell activation may be regulated by a glycoprotein that links to discrete glycosylation patterns on membrane polypeptide domains

T-regulatory Transcription Factor modulation directs lineage adaptation and potency in a pro-inflammatory environment

2019-08-1328:24

In this Authentic Biochemistry episode Dr Guerra unfolds the complex transcription factor and membrane & nuclear- receptor repertoire associated cytokine and chemokine axis activating and maintaining Treg cell differentiation to mediate the Th pro- inflammatory response

Dr Daniel Guerra introduces a novel PCD pathway- ferroptosis- that is linked to excitotoxicity and lipid peroxidation leading to neurodegeneration. Part I

2019-03-2526:20

This is the first part of a diaeventontological framing of lipid peroxidative mechanisms for CNS neurodegeneration. Dr Guerra describes recent published research (JLR 2018 .59:312pp.) and develops some of the key elements of the ferroptosis programmed cell death mechanism leading to oligodendrocyte and neuronal degeneration that will participate in a grander understanding of injury-induced and idiotypic age-associated disease in the CNS. 25 March 2019.

Authentic Biochemistry #3. Dr Guerra verifies the evidence to a future biochemical prolegomena for Alzhiemer's Disease

2019-03-1027:56

In this podcast, Dr Daniel Guerra of Authentic Biochemistry and VerEvMed endeavours to examine the bioenergetic and pro-inflammatory prodromal patho-biochemistry of age-onset Alzheimer's Disease using his diaeventontological toolkit.

The Diaeventontology of Biological Systems

2019-02-2747:23

Dr. Daniel J. Guerra introduces his paradigmatic shift for understanding biochemical phenomena as prolegomena to understanding Alzheimer's Disease.

Introduction to Authentic Biochemistry Podcast

2019-02-2315:26

Dr Daniel Guerra of Authentic Biochemistry in his initial podcast introducing the show and starting off with initial content on current Alzheimer's Disease research

Ischaemic Stroke X. 17 October 25 Authentic Biochemistry Podcast. Dr Dan Guerra

2025-10-1801:01:50

ReferencesCold Spring Harb Perspect.Biol. 2018 Feb; 10(2): a028415.Sci. Signal. 2019;12:eaau2293Stem Cells Int. 2017 Aug 16;2017:2193432Proc Natl Acad Sci U S A. 2023 Jan30;120(6):e2219630120Hunter Garcia. 1975. Franklin's Tower .Blues for Allah. Grateful Deadhttps://music.youtube.com/watch?v=55TOIJxKc74&si=gZFUTJv8Ju2XlPBFBill KreutzmannBob WeirJerry GarciaKeith GodchauxMickey HartPhil LeshDonna GodchauxRobert Hunter 1975 Sandcastles, Glass Camels and Unusual Occurences in the Desert. Blues for Allah. Grateful Dead.https://music.youtube.com/watch?v=puKdKkCA2Ik&si=e15ow1HA_e6fHyvq

Isch-S IX 16October25 Authentic Biochemistry Podcast Dr. Daniel J Guerra

2025-10-1701:01:20

ReferencesFront Cardiovasc Med. 2024 May 13;11:1386733.Eur J Heart Fail . 2021 Jun;23(6):895-905Simon, P. 1970. The Boxer S&Ghttps://music.youtube.com/watch?v=l3LFML_pxlY&si=2ggC3NegOGRFoOk5Bach, JS 1721. Brandenburg Concerto IV. BMV 1049.https://music.youtube.com/watch?v=tp_WeHUKoXM&si=3nyiFKnvrdT71DW6Telemann, GP, 1720 Oboe Concertihttps://music.youtube.com/watch?v=n8XQh78MxqY&si=ryG3pBNefaNHlHG2

ISCH S VIII Authentic Biochemistry Podcast 15October 2025 Dr Daniel J. Guerra

2025-10-1601:01:20

ReferencesCompr Physiol. 2013 Apr;3(2):785–797. Biochimica et Biophysica Acta(BBA) - Molecular Basis of Disease 2015.Volume 1852, Issue 3, March: 421-428Guerra, DJ. 2025. Unpublished LecturesJ Zhejiang Univ Sci B. 2005 Oct 28;6(11):1045–1056McCray, L. 1993 Soulshine. Allman Brothershttps://music.youtube.com/watch?v=UcAmXagv90k&si=s2eYW0sranydR9bSAllman, D. 1971. Little Martha. Eat a Peach lp. Allman Brothershttps://music.youtube.com/watch?v=typ2c8JPkLE&si=aFzABlZ3E5WH9pGu

ISCHS VII Authentic Biochemistry Podcast 14October 2025 Dr Daniel J. Guerra

2025-10-1501:16:37

ReferencesBrain and Cognition 2017. V. 113, April: 10-22J Mol Med (Berl). 2012 Feb;90(2):119-26Molecular Medicine Reports 2015. January 14: 3203-3211Guerra, DJ. 2025. Unpublished Lectures.Joel, B. 1977. The Strangerhttps://music.youtube.com/playlist?list=OLAK5uy_mLHjM5NsmwIHi3xPaTwme_7YCcgSTjafo&si=yNsqCp_8TPvNT_l9

IS VI Authentic Biochemistry Podcast 13 October 2025 Dr. Daniel J. Guerra

2025-10-1401:33:29

ReferencesArch Gen Psychiat, 48 (1991), pp. 563-568Magnetic Resonance Spectroscopy in Psychiatric Brain Disorders, American Psychiatric Press, Washington DC (1994), pp. 49-83Biological Psychiatry 2002. 52, Issue 8, 15 October:823-830J Neuroinflammation. 2025 May 28;22:144. Guerra, DJ. 2025. Unpublished Lectures.Hunter/Garcia. 1970. Brokedown Palace.https://music.youtube.com/watch?v=gzRboWH1E6Y&si=RHYn8ej-BZsSKbo4Schubert, F. 1819. Quintet in A Major. D.667. OP.114https://music.youtube.com/watch?v=g3k81__bwrM&si=Xdl70V7tGPyReCt0

IS V Authentic Biochemistry Podcast Dr Daniel J. Guerra 11October25

2025-10-1201:24:41

ReferencesCurrent Problems in Surgery 2025. Volume 68, July . 101768Stroke: Vascular and Interventional Neurology 2022 Volume 3, Number 2Guerra, DJ. 2025. Unpublished Lectures Simon, P. 1966. Leaves That Are Green. S&G.https://music.youtube.com/watch?v=OTlpdCPrx14&si=xcqpbcW8tNGWZGSxNorth and Zaret. 1965. Unchained Melody. Righteous Brothershttps://music.youtube.com/watch?v=te51eVrFWEc&si=n3MsJJ7oZ1uShcgGLightfoot, G. 1975. Don Quixotehttps://music.youtube.com/watch?v=LJB0nCv0qxk&si=0iootaOq9zbdCXy6Beethoven, LV, 1805. Piano Sonata No. 23 in F minor, Op. 57 "The Appassionata"https://music.youtube.com/watch?v=E5JObP74jcw&si=fZxyvFQuEOY-Q-Dm

Ischaemic Stroke-IS IV Authentic Biochemistry Podcast Dr Daniel J. Guerra 10October25

2025-10-1101:17:13

ReferencesInternational Journal of Molecular Sciences2017. 18(7):1386Int J Mol Sci . 2022 Jul 12;23(14):7697.Sci Rep. 2020 Oct 20;10:17776Mol Cell. 2024 Apr 4;84(7):1338-1353.e8. Cell Metab. 2018 Sep 4;28(3):504-515.e7.Alcohol, 2017-12-01, Volume 65, Pages 51-62Neuroscience, 2023-11-21, Volume533, Pages 22-35Guerra, DJ. 2025 Unpublished Lectures Mozart WA. 1788. Divertimento E Major. K563.https://music.youtube.com/watch?v=E8c83bpOVXo&si=6EG2xcDaB9-c-mBQ

IS III 09October25 Authentic Biochemistry Podcast Dr Daniel J Guerra

2025-10-0901:21:10

ReferencesNeuroscience, 2023-11-21, Volume533, Pages 22-35Autophagy. 2021 Dec;17(12):3992-4009Cell Death Discovery 2024. volume 10, Article number: 200 Autophagy. 2022 Apr;18(4):726-744Guerra, DJGPhD. 2025. Unpublished LecturesRafferty, J. 1977.Baker Street.https://music.youtube.com/watch?v=Fo6aKnRnBxM&si=lYDwqknKv1Du18CrSimon, P. 1963 Bleeker St. from Wed Morning 3AM; lp. Simon and Garfunkelhttps://music.youtube.com/watch?v=xcXoGTACMHA&si=Wr55-ahAtcayIAPGPrine, J. 1971. Hello in Therehttps://music.youtube.com/watch?v=RfwGkplB_sY&si=l-PjfRcedC67wFg-John, E.1972. Mona Lisas and Madhattershttps://music.youtube.com/watch?v=feMawHOpamI&si=c_1Cbf5YJIx8cJMj

Ischaemic Stroke and Intracerebral HemorrhageII 08October25 Authentic Biochemistry Podcast Dr Daniel J GuerraI

2025-10-0901:02:48

ReferencesNeuroscience, 2023-11-21, V.533, Pages 22-35Pharmacological Research 2025.Volume 214, April 107685Front Neurol. 2022 Apr.11;13:804851.Rossini, G. 1829. William Tell Overture.https://music.youtube.com/watch?v=sHQ1Date2v0&si=AXQgrbUq-eOj3529Winwood/Capaldi. 1970. Freedom Rider https://music.youtube.com/watch?v=Qsm1j_dDNtE&si=wd9r8LyeNJY5NGI5

Ischaemic Stroke and Intracerebral HemorrhageIntroduction 07October25.Authentic Biochemistry Podcast 07October25 Dr Daniel J Guerra

2025-10-0851:26

References Peer J. 2018 Nov 23;6:e6021Front Neurol.2022 Apr11;13:804851.Davis, G.Rev. 1960 Death Don't Have no Mercy. Grateful Dead . Live Dead. lp.https://music.youtube.com/watch?v=-9IVP8pCN5U&si=J6Do1-FhfxD8ZzZ-Biber, HI. 1676 The Rosary Sonatas.https://music.youtube.com/watch?v=Z0ypvC5LN6s&si=lBp9iqqe3iEqJlNo

MS.XVII Fine. Authentic Biochemistry Podcast. Dr Daniel J Guerra 06October25

2025-10-0701:01:38

ReferencesNeuromolecular Med . 2024 Jun 1;26(1):22International Journal of Biological Macromolecules2020, Volume 163, 15 November Pages 1599-1617Nature. 2024 Mar 20;627(8005):865–872.Waters./Gilmour/Mason/Wright.1973. Time DSotM Pink Floydhttps://music.youtube.com/watch?v=yl-Ms_ek-kE&si=ay8gE7dkCOfBNjI4McCartney, P.1 970. Maybe I'm Amazedhttps://music.youtube.com/watch?v=slF3EBxZE6A&si=tIGuzL65_9Qr8UkaSimon, P.1966. Flowers Never Bend. PSR&T Simon and Garfunklehttps://music.youtube.com/watch?v=41XVWUL9VTE&si=HeFoIjpZ15MoT5r3Wilson/Love. 1966.. Good Vibrations. Beach Boyshttps://music.youtube.com/watch?v=oMfjgQ8ptrE&si=dZ4S6OkeNehhrzX8Beethoven LV 1807. Triple Concerto C Major. Op. 56https://music.youtube.com/watch?v=pkXGtE8_cig&si=NK4uP41aG2HoQmdn

MS XVI Authentic Biochemistry Podcast Dr. Daniel J Guerra 05October25

2025-10-0601:16:15

ReferencesFront Nutr. 2020 Jan 31;7:3.Nature .2024 Mar;627(8005):865-872Brain, Behavior, and Immunity .2024 116, February: 140-149Guerra, DJ. 2025. Unpublished Lectures.Lennon/McCartney. 1969. Let it Behttps://music.youtube.com/watch?v=QDYfEBY9NM4&si=URNgYVOl74n7IkNGTchaikovsky., PI. 1880. . Capriccio Italienhttps://music.youtube.com/watch?v=EhSb37hIryY&si=-2N4t8u2YBs9L6DT

MS XV Authentic Biochemistry Podcast Dr Daniel J Guerra 04October25

2025-10-0554:46

ReferencesJACC 2017;69:1952-1967FEBS Letters1998. Volume 430, Issue 3, 3 July Pages 154-157Nature. 2024 Mar 20;627(8005):865–872.Molecular Neurobiology (2020) 57:5167–5176HHaydn , M. 1766 HobXXII 3 Cäcilienmesse Missa Cellensis in honorem Beatissimae Virginis Mariae in C majorhttps://youtu.be/wmvJlbakt-sHarrison, G. 1968. While My Guitar Gently Weeps White Album Beatleshttps://music.youtube.com/watch?v=YFDg-pgE0Hk&si=8KuffJ40UDIbtSs8Dylan, B.1962. Don't Think Twice Its Alrighthttps://music.youtube.com/watch?v=1iHhWh9FtsQ&si=Eex0R4pbFkrL-Jtn

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