CCO Infectious Disease Podcast

Weekly updates on new data and best practices in patient care for a variety of infectious diseases including COVID-19, HIV, and viral hepatitis, from Clinical Care Options. Gain practical strategies and earn CME/CE credit for selected episodes.

COVID-19 in the EU: Inpatient Treatment of Mild to Moderate COVID-19 in Patients Who Are Immunocompromised

In this episode, Martin Witzenrath, MD, FERS, and Michele Bartoletti, MD, PhD, discuss the management of mild to moderate COVID-19 in patients who are immunocompromised, including:Initial workup, which may include laboratory tests and/or imagingLatest data on the use of remdesivir or nirmatrelvir plus ritonavir for mild to moderate COVID-19, including considerations for drug–drug interactions Presenters:Martin Witzenrath, MD, FERSMedical DirectorCharite Centrum 12Internal Medicine & DermatologyProfessor and Chair for Respiratory Medicine and Critical CareDepartment of Infectious Disease, Respiratory Medicine and Critical CareCharite Campus Mitte/Campus Virchow Klinikum/Campus Benjamin FranklinCharite – University of BerlinBerlin, GermanyMichele Bartoletti, MD, PhDAssociate Professor of Infectious DiseasesDepartment of Biomedical SciencesHumanitas UniversityPieve Emanuele (MI), ItalyHead of Infectious Diseases UnitIRCCS Humanitas Research HospitalRozzano (MI), Italy Link to full program: https://bit.ly/4gu2gcUDownloadable slides: https://bit.ly/3CGlDBSGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

02-06
13:27

Defining Best Practices in HBV Care

In this episode, Patricia D. Jones, MD, MSCR; Mindie H. Nguyen, MD, MAS, AGAF, FAASLD; and patient advocate, Jennifer Wild, MS, RN, OCN, discuss best practices in hepatitis B virus (HBV) care, including: 2023 CDC HBV screening recommendationsSummary of guideline recommendations for hepatitis delta virus (HDV) screening Use of HDV reflex testing to avoid loss to follow-up2024 WHO HBV treatment recommendations, including recommendations for pregnant persons Presenters:Patricia D. Jones, MD, MSCRAssociate Professor of Clinical MedicineDirector of Clinical Operations-HepatologyDivision of Digestive Health and Liver DiseasesDepartment of MedicineUniversity of Miami Miller School of MedicineSylvester Comprehensive Cancer CenterMiami, FloridaMindie H. Nguyen, MD, MAS, AGAF, FAASLDProfessor of Medicine (GI & Hepatology,Liver Transplant)Professor of Epidemiology & Population Health(by Courtesy)Director of Hepatology ClerkshipFaculty Search LENS Advocates,Stanford Department of MedicineFaculty Fellow, Stanford Center for Innovationin Global HealthMember, Stanford Cancer Institute, Maternal &Child Health Research Institute, & Stanford Bio-CStanford, CaliforniaPast Chair: HBV SIG, The American Association for the Study of Liver Diseases (AASLD)28th President: The International Association for the Study of the Liver (IASL)Jennifer Wild, MS, RN, OCNClinical Nurse – GI Medical OncologyUCSF Cancer CenterSan Francsico, CaliforniaLink to full program: https://bit.ly/4j973TNDownloadable slides: https://bit.ly/3WQkIWlGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

02-05
34:14

COVID-19 in the EU: Current Trends and Risk Factors for Severe COVID-19 Progression

In this episode, Cristina Mussini, MD, Martin Witzenrath, MD, FERS, and Michele Bartoletti, MD, PhD, discuss:Current SARS-CoV-2 trends in the EURisk factors for severe COVID-19 outcomes, including the spectrum of risk based on immune system statusFactors that may affect vaccine efficacy in chronic lymphocytic leukemia and other lymphoid malignanciesConsiderations for determining people at high risk for COVID-19 progression Presenters:Cristina Mussini, MDFull Professor of Infectious DiseasesDivision of Infectious DiseasesUniversity of Modena and Reggio EmiliaModena, ItalyMartin Witzenrath, MD, FERSMedical DirectorCharite Centrum 12Internal Medicine & DermatologyProfessor and Chair for Respiratory Medicine and Critical CareDepartment of Infectious Disease, Respiratory Medicine and Critical CareCharite Campus Mitte/Campus Virchow Klinikum/Campus Benjamin FranklinCharite – University of BerlinBerlin, GermanyMichele Bartoletti, MD, PhDAssociate Professor of Infectious DiseasesDepartment of Biomedical SciencesHumanitas UniversityPieve Emanuele (MI), ItalyHead of Infectious Diseases UnitIRCCS Humanitas Research HospitalRozzano (MI), ItalyLink to full program: https://bit.ly/4gu2gcUDownloadable slides: https://bit.ly/42IlpELGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

02-05
16:48

Simplified HCV Care in Sexual and Reproductive Health Clinics

In this episode, Tzu-Hao (Howard) Lee, MD; Tatyana Kushner, MD, MSCE; and patient advocate Andrew Reynolds discuss hepatitis C virus (HCV) care in men who have sex with men and pregnant people, including:HCV disease burden in the United StatesScreening recommendations Strategies to overcome barriers to HCV screeningTreatment recommendations, including simplified treatment guidance and considerations for pregnant peopleStrategies to improve treatment uptakePresenters:Tzu-Hao (Howard) Lee, MDAssistant ProfessorSection of Gastroenterology and Hepatology, Department of MedicineDivision of Abdominal Transplant, Department of SurgeryBaylor College of MedicineHouston, TexasTatyana Kushner, MD, MSCEAssociate ProfessorDivision of Gastroenterology/HepatologyDepartment of Obstetrics & GynecologyWeill Cornell MedicineNew York, New YorkAndrew ReynoldsDirector, Health of People Who Use DrugsSan Francisco AIDS FoundationSan Francisco, CaliforniaTo access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. Link to full program:https://bit.ly/4j973TNDownloadable slides: https://bit.ly/4gXuBcu

01-08
01:04:44

Key PBC Studies From AASLD 2024

In this episode, Sonal Kumar, MD, MPH, discusses key findings from primary biliary cholangitis (PBC) studies presented at AASLD 2024, including:ELATIVE, a phase III trial of elafibranor for PBCRESPONSE, a phase III trial of seladelpar for PBCASSURE, another phase III trial of seladelpar for PBCPresenter:Sonal Kumar, MD, MPHDirector, Clinical Gastroenterology and HepatologyAssistant Professor of MedicineWeill Cornell Medical CollegeNew York, New YorkLink to full program:https://bit.ly/41tvSDuGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

01-07
20:16

Understanding Current Trends and Risk Factors for Progression to Severe COVID-19

Listen in as Stephen Cantrill, MD, FACEP; Rajesh T. Gandhi, MD; and Payal K. Patel, MD, MPH, FIDSA, discuss current trends in and risk factors for progression to severe COVID-19, including for those for whom COVID-19 is not their primary concern when presenting to the emergency department (ED). Key topics of discussion include: How to complete a comprehensive patient workup in the EDConsiderations regarding pulse oximetryRisk stratification—what places patients at higher risk of severe disease?A detailed patient case to illustrate key takeawaysPresenters:Stephen Cantrill, MD, FACEP​Associate Director and Medical Director (Retired) ​Department of Emergency Medicine​Denver Health Medical Center​Associate Professor ​Department of Emergency Medicine​University of Colorado Health Sciences Center​Denver, ColoradoRajesh T. Gandhi, MD​Massachusetts General Hospital​Professor of Medicine​Harvard Medical School​Boston, MassachusettsPayal K. Patel, MD, MPH, FIDSA​Systemwide Director of Antimicrobial Stewardship​Associate Professor, Division of Infectious Diseases​Intermountain Health​Salt Lake City, UtahLink to full program:https://bit.ly/4fs7HcbGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

01-02
16:01

Simplified HCV Screening and Care in People Who Use Drugs

In this episode, Stacey B. Trooskin, MD, PhD, MPH, Mark S. Sulkowski, MD, FIDSA, FAASLD, and Ronni Marks discuss hepatitis C virus (HCV) screening and treatment, focusing on people who use drugs, and highlight the following topics:Screening recommendationsStrategies to improve HCV screeningHCV testingTreatment goalsStrategies to improve HCV treatment uptakePresenters:Stacey B. Trooskin, MD, PhD, MPHExecutive Medical OfficerMazzoni CenterFaculty, University of PennsylvaniaPerelman School of MedicinePhiladelphia, PennsylvaniaMark S. Sulkowski, MD, FIDSA, FAASLDProfessor of MedicineDirector, Division of Infectious Diseases Johns Hopkins Bayview Medical CenterJohns Hopkins University School of MedicineBaltimore, MarylandRonni MarksFounder/Director, The Hepatitis C Mentor and Support Group (HCMSG)Patient AdvocateNew York, New YorkLink to full program:https://bit.ly/4grbwPT

12-23
01:08:21

Inpatient Treatment for Mild to Moderate COVID-19

Listen in as Stephen Cantrill, MD, FACEP; Rajesh T. Gandhi, MD; and Payal K. Patel, MD, MPH, FIDSA, discuss best practices in treating patients hospitalized with mild to moderate COVID-19, including: Current guidelines from the Infectious Diseases Society of America and National Institutes of Health How to optimize therapy selection based on patient risk factors, including key data supporting best practicesA detailed patient case to illustrate key takeawaysPresenters:Stephen Cantrill, MD, FACEP​Associate Director and Medical Director (Retired) ​Department of Emergency Medicine​Denver Health Medical Center​Associate Professor ​Department of Emergency Medicine​University of Colorado Health Sciences Center​Denver, ColoradoRajesh T. Gandhi, MD​Massachusetts General Hospital​Professor of Medicine​Harvard Medical School​Boston, MassachusettsPayal K. Patel, MD, MPH, FIDSA​Systemwide Director of Antimicrobial Stewardship​Associate Professor, Division of Infectious Diseases​Intermountain Health​Salt Lake City, UtahLink to full program: https://bit.ly/4fs7HcbGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

12-19
16:01

Emerging Therapies for Pruritus in PBC

Clinical gaps in the treatment of pruritus in primary biliary cholangitis (PBC) remain. In this episode, taken from a recent symposium, Marlyn J. Mayo, MD; Stuart C. Gordon, MD; and Pam Rivard, RN, a person living with PBC, discuss emerging therapies currently in clinical trials for the management of this disease that can dramatically affect patients’ quality of life.Listen as they discuss:Gaps in current managementPatient perspectives: why we should not dismiss itching as an underlying psychologic problemPPAR agonists and how they affect pruritusBEZURSO and FITCH ELATIVEENHANCE and RESPONSEIBATs (inhibitors of bile acid transport)GLIMMERCommon questionsPresenters:Marlyn J. Mayo, MDProfessor of Internal MedicineDivision of Digestive & Liver DiseasesUT Southwestern Medical CenterDallas, TexasStuart C. Gordon, MDProfessor of MedicineWayne State University School of MedicineDirector, Division of HepatologyHenry Ford HealthDetroit, MichiganPam Rivard, RNPerson living with PBCLink to full program: https://bit.ly/3Dnfb2E

12-18
23:34

Clinical Management of Pruritus in PBC

Although there is currently no FDA-approved treatment for pruritus in primary biliary cholangitis (PBC), symptoms can be mitigated with nonpharmacologic or pharmacologic agents. In this episode, Marlyn J. Mayo, MD; Stuart C. Gordon, MD; and Pam Rivard, RN, a person living with PBC, discuss the clinical management of pruritus in PBC, including:Pruritus assessment toolsOptimal use of tools, including frequency of assessmentCurrent management of pruritusNonpharmacologic interventionsPharmacologic agentsStrategies to optimize assessment and management of pruritusCollaborative careDevelopment of a treatment planOngoing assessment and adjustment of therapyResources and support for patientsPresenters:Marlyn J. Mayo, MDProfessor of Internal MedicineDivision of Digestive & Liver DiseasesUT Southwestern Medical CenterDallas, TexasStuart C. Gordon, MDProfessor of MedicineWayne State University School of MedicineDirector, Division of HepatologyHenry Ford HealthDetroit, MichiganPam Rivard, RNPerson living with PBCLink to full program: https://bit.ly/3Dnfb2E

12-18
21:18

Living With Pruritus in PBC: A Patient Perspective

In this episode, Marlyn J. Mayo, MD; Stuart C. Gordon, MD; and Pam Rivard, RN, a person living with primary biliary cholangitis (PBC), discuss the burden of pruritus in PBC and the impact it has on quality of life, including both physical and mental health, from a patient’s perspective.Presenters:Marlyn J. Mayo, MDProfessor of Internal MedicineDivision of Digestive & Liver DiseasesUT Southwestern Medical CenterDallas, TexasStuart C. Gordon, MDProfessor of MedicineWayne State University School of MedicineDirector, Division of HepatologyHenry Ford HealthDetroit, MichiganPam Rivard, RNPerson living with PBCLink to full program: https://bit.ly/4gDGDaB

12-18
12:19

CCO Independent Conference Coverage of IDWeek and Glasgow 2024

In this episode, Jean-Michel Molina, MD, PhD, and Joseph J. Eron, Jr., MD, discuss results from key clinical trials on HIV prevention and treatment as well as sexually transmitted infection (STI) prevention presented at IDWeek and Glasgow 2024, including:PURPOSE 1 and 2 comparing lenacapavir injection vs oral TDF/FTCTRIO Health Cohort and OPERA examining long-acting cabotegravir as PrEPDOLCE comparing DTG/3TC as first-line therapy in treatment-naive patients with HIVPRIDOX evaluating the use of DoxyPEP on STI incidence in men who have sex with men on PrEPPresenters:Jean-Michel Molina, MD, PhDProfessor of Infectious DiseasesUniversity of Paris CitéHead of the Department of Infectious DiseasesHospital Saint-Louis and lariboisièreParis, FranceJoseph J. Eron, Jr., MDProfessor of Medicine, School of MedicineHerman and Louise Smith Distinguished ProfessorChief, Division of Infectious DiseasesDirector, Clinical Core, UNC Center for AIDS ResearchAdjunct Professor of Epidemiology, Gillings School of Global Public HealthUniversity of North Carolina at Chapel HillChapel Hill, North CarolinaLink to full program: https://bit.ly/3BBaZvJ

12-17
49:28

Recent Advances in PBC Management

In this episode, Christopher L. Bowlus, MD, discusses recent advances in the management of primary biliary cholangitis (PBC), including:Treatment goalsUse of PPAR agonists for the treatment of PBCClinical trial results for elafibranor (ELATIVE), seladelpar (RESPONSE), and bezafibrate (BEZURSO)Presenter:Christopher L. Bowlus, MDLena Valente Professor and ChiefDivision of Gastroenterology and HepatologyUniversity of California Davis School of MedicineSacramento, CaliforniaLink to full program: https://bit.ly/41tvSDuGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

12-13
08:46

Be an Ally: Navigating the Healthcare System as a Transgender Individual With HIV

In this episode, a transfemme nonbinary individual living with HIV shares her experience navigating the healthcare system, alongside her infectious disease physician, Michelle D. Collins-Ogle, MD, FAAP, FPIDS, AAHIVS. Hear them discuss key considerations when caring for gender-diverse individuals, including: Understanding how people are more than just a diagnosis Prioritizing individuals’ needs and providing whole-person care using shared decision-makingStrategies to make an environment more affirming and welcoming How to be an ally to transgender individualsListen to the individual in front of youHear what they’re telling youMake sure they are being affirmed and seenLink to the full program:https://bit.ly/3AAOGpvGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

11-13
32:05

Key HIV Studies Influencing My Practice Following HIVR4P 2024—Drs . Linda-Gail Bekker and Meredith Clement

In this rapid webinar, Meredith E. Clement, MD, and Linda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhD, provide an overview of important topics and studies presented at HIVR4P 2024, including:Expanding PrEP options based on results from PURPOSE 2, IMPOWER-22, IMPOWER-24, IPM 054, MTN-025/HOPE OLE, CATALYST, and the HPTN 084 substudyImplementing injectable PrEP based on results from PEPFAR, the USAID DISCOVER-Health LA CAB Demonstration Project in Zambia, and the LA CAB PrEP Rapid Start Model in Public Health ClinicsImproving PrEP uptake based on results from SPrEP and HPTN 091  Presenters:Meredith E. Clement, MDAssociate ProfessorInfectious DiseasesLouisiana State University Health Sciences CenterNew Orleans, LouisianaLinda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhDDirector and Professor, The Desmond Tutu HIV Centre, UCTCEO, The Desmond Tutu Health FoundationCape Town, South AfricaTo access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. Link to full program: https://bit.ly/3NJIDSA

10-30
46:26

Be an HPV Vaccine Champion: Reaching Underserved Populations

Listen in as Rebekah Fenton, MD, MPH, and Sharon G. Humiston, MD, MPH, discuss strategies to achieve health equity in HPV vaccination, including:Trends among males vs femalesMessaging considerations for those from diverse populations (eg, LGTBQ+ and rural communities)How healthcare professionals can address barriers to careThen, hear answers from the experts to frequently asked questions regarding HPV vaccination recommendations, timing, and example case studies. Presenters:Rebekah Fenton, MD, MPHAdolescent Medicine PhysicianAlivio Medical CenterChicago, IllinoisSharon G. Humiston, MD, MPHDirector for ResearchAssociate Editor of IZ-ExpressImmunize.orgRochester, New YorkTo access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. Follow along with the slides: https://bit.ly/4flDxYbLink to full program: https://bit.ly/4f06tW4

10-29
26:10

Key HIV Studies Influencing My Practice Following HIVR4P 2024—Drs . Linda-Gail Bekker and Meredith Clement

In this rapid webinar, Meredith E. Clement, MD, and Linda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhD, provide an overview of important topics and studies presented at HIVR4P 2024, including:Expanding PrEP options based on results from PURPOSE 2, IMPOWER-22, IMPOWER-24, IPM 054, MTN-025/HOPE OLE, CATALYST, and the HPTN 084 substudyImplementing injectable PrEP based on results from PEPFAR, the USAID DISCOVER-Health LA CAB Demonstration Project in Zambia, and the LA CAB PrEP Rapid Start Model in Public Health ClinicsImproving PrEP uptake based on results from SPrEP and HPTN 091 Presenters:Meredith E. Clement, MDAssociate ProfessorInfectious DiseasesLouisiana State University Health Sciences CenterNew Orleans, LouisianaLinda-Gail Bekker, MBChB, DTMH, DCH, FCP(SA), PhDDirector and Professor, The Desmond Tutu HIV Centre, UCTCEO, The Desmond Tutu Health FoundationCape Town, South AfricaTo access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. Link to full program: https://bit.ly/3NJIDSA

10-28
46:26

Strategies to Improve HPV Vaccine Uptake: Effective Vaccine Messaging

Listen in as Rebekah Fenton, MD, MPH, and Sharon G. Humiston, MD, MPH, discuss strategies to improve your messaging techniques with the HPV vaccine, including:Persisting in vaccine recommendation after initial refusalEducating patients and their families togetherEnsuring staff are trained to correctly answer questionsKnowing when interested patients in your state can consent to vaccination without needing parental consentPresenters:Rebekah Fenton, MD, MPHAdolescent Medicine PhysicianAlivio Medical CenterChicago, IllinoisSharon G. Humiston, MD, MPHDirector for ResearchAssociate Editor of IZ-ExpressImmunize.orgRochester, New YorkTo access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. Follow along with the slides: https://bit.ly/4flDxYbLink to full program: https://bit.ly/4f06tW4 

10-28
13:35

The True Burden of HPV Infection

Listen in as Sharon G. Humiston, MD, MPH, discusses current trends in HPV, including:Incidence and prevalence trends in the USSex-related features of HPV-attributable cancersHow HPV vaccination uptake can prevent certain types of cancerCurrent guidelines and recommendations for HPV vaccinationPresenter:Sharon G. Humiston, MD, MPHDirector for ResearchAssociate Editor of IZ-ExpressImmunize.orgRochester, New YorkTo access all of our new podcast episodes, subscribe to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. Follow along with the slides: https://bit.ly/4flDxYbLink to full program: https://bit.ly/4f06tW4

10-28
16:45

Making Addiction Care an Integral Part of HIV Care

In this episode, Kathleen Page, MD, and Glenn J. Treisman, MD, PhD, discuss the interplay between addiction and HIV. Learn as they share their approaches to reframing the conversation about addiction and overcoming barriers to effective addiction care for people living with HIV.Presenters:Kathleen Page, MDProfessorInfectious DiseasesJohns Hopkins School of MedicineBaltimore, Maryland Glenn J. Treisman, MD, PhDEugene Meyer III Professor of Psychiatry and MedicineJohns Hopkins University School of MedicineBaltimore, MarylandDownloadable slides:https://bit.ly/3TR3OVVProgram:https://bit.ly/3WB2VCO

10-08
30:46

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