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Daily Medical News

Author: MDedge

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The latest clinical medicine and health policy news for healthcare professionals, delivered each weekday by host Nick Andrews and MDedge editors. The information in this podcast is provided for informational and educational purposes only.
207 Episodes
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More phase 3 ubrogepant data published as FDA decision nears By Jake Remaly An acute treatment for migraine shows positive results in a phase 3 trial. Other news: Gunshot wound victims are at high risk for readmission Individuals who sustain gunshot wounds have an increased risk for rehospitalization years, and even decades, after their initial injury. FDA expands use of Toujeo to childhood type 1 diabetesThe new indication includes children as young as 6 years of age. FDA approves Tula system for recurrent pediatric ear infectionsThe system can be used in an office setting under local anesthesia. Higher risk of bipolar disorder, depression, anxiety found with autismThe study supports the importance of early and ongoing surveillance, the researchers said.   You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.
Quantifying the EHR connection to burnout By Gregory Twachtman New research puts a more standard, quantifiable measure to the relationship between EHR usability and burnout. Other news: CDC finds that efforts to reduce new HIV infections have stalled The agency has proposed a federal initiative to improve diagnosis, treatment, and prevention in areas of greatest need throughout the country. Cardiac arrests peak with pollution in Japan The incidence of out-of-hospital cardiac arrests in Japan increased on days when counts of particulate matter spiked from the day before. High recurrence, shortening cycle length in bipolar disorder associated with several biomarkers The results could lead to research aimed at preventive action. Naturopaths emphasize role of diet in atopic dermatitis Allopathic and naturopathic providers diverge in opinions on the role of diet in cause and treatment of AD. You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.
Nearly one in five U.S. adolescents have prediabetes By Bianca Nogrady   Nearly one in five adolescents and one in four young adults in the United States have prediabetes, with a higher prevalence among males.     Other news:   Antibiotic use may increase the risk of Parkinson’s disease Associations were found for broad-spectrum antibiotics and those that act against anaerobic bacteria and fungi.   2019-2020 flu season starts off full throttle The five states with the highest activity were Alabama, Georgia, Louisiana, Mississippi, and Texas.   Large state disparities seen for lung cancer screening In Massachusetts, the rate of lung cancer screening in high-risk individuals is nearly 25 times higher than the rate in Nevada.   AGA releases clinical practice update for pancreatic necrosis The update includes 15 recommendations based on a comprehensive literature review and the experiences of leading experts.     You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.
ACGME deepening its commitment to physician well-being, leader says By Doug Brunk   Positive social relationships with others are crucial to joy and well-being in the practice of medicine.   You can take the MDedge Podcasts survey by clicking here.   Other news:   CMS announces application process for Direct Contracting model Letters of intent to participate are due by Dec. 10.   ART treatment at birth found to benefit neonates with HIV Starting antiretroviral therapy within an hour after birth improves immune response.   Certolizumab safety profile varies widely across indications Systemic corticosteroid use and BMI impact risk of serious adverse events with certolizumab.   Inexperience is the main cause of unsafe driving among teens Cell phone use nearly doubles the proportion of teen drivers who die in crashes, from 7% to 13%.   You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.  
Managing pain in kids during minor procedures: A tricky balance By Doug Brunk   Other News: Supplemental MRI found to benefit women with dense breast tissue The trial was not large enough to examine the effect of MRI screening on breast cancer-specific or overall mortality.   Late-onset MS is often more severe than earlier-onset MS Late-onset MS often has faster accrual of disability and might require different treatment options.   DAPA-HF: Dapagliflozin benefits regardless of age, HF severity The SGLT2 inhibitor had similar efficacy in the elderly, and across the spectrum of baseline symptom status.   Obesity dropping in kids aged 2-4 years in WIC program During 2010-2016, the prevalence of obesity among this group significantly declined in 73% of U.S. states and territories.   *  *  *     You can take the MDedge Podcasts survey by clicking here.   You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.  
We bring you the best-of Dr. RK, our closing segment of the Psychcast by MDedge.  Renee Kohanski, MD, a clinical psychiatrist in New England, is the voice and mind behind the Dr. RK segment.  If you like Dr. RK, you can find more from the Psychcast and from MDedge Psychiatry here.   
In this special Thanksgiving episode, MDedge presents Ilana Yurkiewicz, MD, who is the voice and mind behind the Clinical Correlation segment of Blood & Cancer.  Clinical Correlation is a segment all about the human side of hematology and oncology care.  You can find more from Dr. Yurkiewicz and Blood & Cancer, the official podcast of MDedge Hematology/Oncology here.        
Atopic dermatitis acts differently in certain populations By Randy Dotinga   AD may require different treatments depending on age, ethnicity. You can take the MDedge Podcasts survey by clicking here.   Other news: Regular use of disinfectants at work associated with increased risk of COPD Clinicians should look for sources of exposure to cleaning products and disinfectants.   Data build on cardiovascular disease risk after GDM, HDP Risk factors may be elevated as soon as the first postpartum year.   Survey: Cancer-related pain, opioid use up since 2018 Almost half of patients with cancer did not use anything to manage related symptoms, according to an ASCO poll.   Chronic pain more common in women with ADHD or ASD Treating patients’ ADHD helps to reduce the pain in some cases.     You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets  
OA management guidelines forgo treatment hierarchy or order but emphasize severity, patient risk factors By Jeff Craven   The guidelines lay out a wide range of treatment options without an algorithm. ***   You can take the MDedge Podcasts survey by clicking here.   ***   Other news: Colchicine cut post-MI CVD events Colchicine fulfilled the promise first seen in CANTOS that anti-inflammatory treatment can reduce cardiovascular disease events.   Large population-based study underscores link between gout, CVD event risk The relationships between gout and fatal and nonfatal CVD events weren’t weakened by allopurinol use or serum urate lowering to treatment target.   Baseline subtypes predict dementia and death in patients with Parkinson’s disease Clinicians should assess cognitive and psychiatric symptoms at baseline.   Metformin after gestational diabetes: Lessons from landmark diabetes prevention trial The drug should be front and center for clinicians who hope to stave off the “remarkable” incidence of type 2 diabetes after GDM.   You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.      
Cannabis frequently is used for endometriosis pain By Jim Kling   Survey finds more than a third of patients have used marijuana or CBD.   You can take the MDedge Podcasts survey by clicking here.     Other News: Treating LDL to below 70 reduces recurrent stroke Patients had fewer events than those with an LDL cholesterol level between 90 and 110.   Geriatric IBD hospitalization carries steep inpatient mortality A major unmet need exists for better guideline-directed management of geriatric patients hospitalized for IBD.   Two national analyses confirm safety of 9vHPV vaccine Among 28 million doses delivered since 2015, 7,244 adverse events were reported – an event rate of 1 per 7 million vaccinations.   Early onset of atopic dermatitis linked to poorer control Children who develop atopic dermatitis in the first 2 years of life are more likely to have poorly controlled or persistent disease.   You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.
Ask about vaping in patients with respiratory symptoms, CDC saysBy Andrew Bowser "Do you vape?" may be one of the most important questions you ask patients this winter.  You can take the MDedge Podcasts survey by clicking here.   Other News: Newborns' maternal protection against measles wanes within 6 monthsInfants born in a country with no endemic measles are no longer adequately protected by maternal antibodies at 6 months. Ultrasound distinguishes early, late-stage endometriosis Presurgical ultrasounds help predict endometriosis stage and ensure that the patient gets to the right surgeon. Open enrollment 2020: Activity down on Healthcare.govMore than 700,000 plans were selected in week 3 of open enrollment.  Vaping front and center at Hahn's first FDA confirmation hearing Dr. Stephen Hahn faced questions from both sides of the aisle on youth vaping.   You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.  
Hepatitis B debrief: Key themes that emerged at AASLD By Andrew Bowser   Hot topics included HBV natural history, novel therapies, and prevention.   You can take the MDedge Podcasts survey by clicking here.   Other News: Inpatient care declining among family physicians Shrinking scope of practice reflects trends in employment and hospital privileges.   Ubrogepant may relieve migraine pain at 2 hours More patients who received the oral CGRP receptor antagonist were free of pain 2 hours later, compared with patients who received placebo.   Not all lung cancer patients receive treatment Reasons include metastasis and refusal, and rates by state vary from 8% to 30%, the American Lung Association reports.   Melanoma incidence drops in younger age groups Fewer teens and young adults developed melanoma between 2006 and 2015, while incidence increased in older adults.   You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.    
Early postmenopausal risk management leads to ‘optimum health’ for women By Jeff Craven   There is an opportunity at the onset of menopause to identify risks and initiate preventive strategies.   You can take the MDedge Podcasts survey by clicking here.   Other News:   Rand analysis of proposed Medicare buy-in uncovers surprising findings Allowing people aged 50-64 to buy into Medicare might drive up individual market premiums.   Children may develop prolonged headache after concussion Headache after pediatric concussion may present as migraine, chronic daily headache, tension-type headache.   The TWILIGHT of aspirin post-PCI for ACS? Patients do better post-PCI for non-ST-elevation ACS with ticagrelor monotherapy   Support for medical marijuana transcends political affiliation Use by cancer patients supported by over 80% of survey respondents, regardless of party     You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.
ISCHEMIA trial hailed as practice changing By Bruce Jancin The largest-ever RCT of initial invasive versus conservative management of stable ischemic heart disease makes waves.   You can take the MDedge Podcasts survey by clicking here.   Other news: Feds propose new price transparency rules in health care The goal of the proposal is to give consumers enough information to shop around for medical services.   Most charity assistance programs do not cover prescriptions for uninsured patients Cancer or cancer-related treatments were covered by 41% of programs, and 34% provided assistance for genetic or rare diseases.   DAPA-HF: Dapagliflozin’s HFrEF efficacy confirmed in nondiabetics Further analyses from the DAPA-HF trial showed dapagliflozin cut death and heart failure events in HFrEF patients with no diabetes.   Suicide screening crucial in pediatric medical settings Screening can take as little as 20 seconds.   You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.    
Are you operating in the black when it comes to vaccine administration? By Doug Brunk   Follow these tips to ensure your practice isn’t losing money on vaccine delivery.   *  *  *   You can take the MDedge Podcasts survey by clicking here. *  *  *   Other news:   FDA panel supports Vascepa expanded indication for CVD reduction Icosapent ethyl (Vascepa), purified eicosapentaenoic acid, got unanimous support from an FDA panel for a new indication of reducing CVD events.   Vaping-linked lung injury: 2,172 cases, 42 deaths Forty-two deaths from EVALI have been confirmed in 24 states and the District of Columbia.   Open enrollment 2020: HealthCare.gov activity down from last year Nevada opened its own exchange this year and moved off the federal system.   Survey asks adults: How likely are you to develop dementia? Adults are worried about dementia and will do anything to prevent it. Except talk to their doctor.   You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.
ATTEST: AFib ablation slows progression to persistence By Mitchel Zoler   AFib ablation cut the rate of paroxysmal to persistent arrhythmia progression by 89%, compared with medical management.   You can take the MDedge Podcasts survey by clicking here.   Other stories:   FDA panel rejects new empagliflozin indication for type 1 diabetes Panelists voted 14-2 against the application and criticized the limited data supporting the application.   ACP recommends ways to address rising drug prices One of the College’s suggestions is for the Medicare Part D low-income subsidy program to be modified.   Drug spending driving up Part B premiums and deductibles The standard premium will climb 6.7% in 2020.   Methotrexate affected joint erosions, not pain, in patients with erosive hand OA The results were observed for 10 mg methotrexate per week at 3 months and 12 months.   You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.
Kratom: Botanical with opiate-like effects increasingly blamed for liver injury By Will Pass   Kratom-associated liver damage involves a mixed pattern of hepatocellular and cholestatic injury.   You can take the MDedge Podcasts survey by clicking here.   DACA lands before Supreme Court Physician organizations argue that access to health care would be demeaned if DACA-affected doctors and trainees were forced to leave the U.S.   Reappraise standard treatment of comorbid insomnia/depression Should you focus on treating the depression before tackling the insomnia?   Fentanyl-related deaths show strong regional pattern Overdose death rates for cocaine, heroin, and fentanyl are high in the East and low in the West.   Even low-dose steroids increase DMARD infection risk Concomitant use of low-dose steroids increases the risk of serious infections with antirheumatic drugs.   You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.  
Tide beginning to turn on vaccine hesitancy By Doug Brunk   Pushback against antivaccination campaigns and advocates is stronger than ever. You can take the MDedge Podcasts survey by clicking here.   Other news: Low LDL-C and blood pressure can reduce lifetime risk of CVD by 80% The effects were seen in those with genetic variants linked with low LDL cholesterol and systolic blood pressure.   Statins in children cut long-term CVD risk in familial hypercholesterolemia There were no cardiovascular-related deaths and one event in treated patients who were followed for 20 years.   Expert reviews strategies for diagnosing, treating onychomycosis There is no such thing as a classical presentation of onychomycosis.   Small nodules, big problems: AI's role in thyroid nodule diagnosis A novel algorithm for benign thyroid nodules showed good sensitivity and specificity.   You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.
CDC identifies probable culprit in vaping lung injuries By Therese Borden   In addition, obtaining vaping devices from informal sources, such as from a dealer, off the street, or from a friend, was more likely to be linked to EVALI.   You can take the MDedge Podcasts survey by clicking here.   CDC identifies probable culprit in vaping lung injuriesCannabis use or abuse among the young was associated with adverse cardiovascular consequences in two studies.   Patients taking TNF inhibitors can safely receive Zostavax Investigators found no confirmed varicella infection cases at 6 weeks.   Daily aspirin might cut risk of fibrosis progression in NAFLD The researchers did not find a similar protective effect for NSAIDs other than aspirin.   Medicare beneficiaries pay most for Alzheimer’s Long-term care takes a toll on beneficiaries with Alzheimer’s and Parkinson’s disease. . You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.
Court strikes down Trump’s conscience rule By Alicia Gallegos The measure would have allowed clinicians to refuse to provide medical care to patients for religious or moral reasons.   *  *  *   You can take the MDedge Podcasts survey by clicking here.   *  *  * Other Stories:   Vitamin D, omega-3 fatty acids do not preserve kidney function in type 2 diabetes After 5 years of follow-up, the supplements showed no significant difference in change in eGFR, compared with placebo.   Mandatory OSA treatment for truckers lowers insurance costs Treated truckers saw health care savings that could help offset the costs of obstructive sleep apnea programs.   Hepatitis C vaccine alters viral trajectory, but fails in chronic infection protection First-ever randomized study does suggest changes in peak HCV RNA and an HCV RNA change after infection.   Lung cancer on the decline, but still higher among men than women CDC stresses universal screening for smoking and other lung cancer risk factors.   You can contact the MDedge Daily Medical News by emailing us at podcasts@mdedge.com or following us on Twitter at @MDedgeTweets.
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