Send us a text GLP-1 is a gut-derived hormone designed to signal the pancreas to produce insulin—but in its natural form, it’s notoriously short-lived. In this Decoding Health segment, we break down why endogenous GLP-1 has an ultra-short half-life (about three minutes), and how the enzyme DPP-4 rapidly “clips” incretin hormones by targeting specific amino acids near the N-terminus—effectively destroying the signal before it can last. You’ll learn how GLP-1 receptor agonist drugs were enginee...
Send us a text Dr. Robert H. Lustig joins the show to break down why today’s metabolic health crisis is not a personal failure problem, but an environment problem, and how the power structure shaping food, policy, and public health has shifted in ways most people have not tracked. From “poisonous calories” and ultra-processed food to microplastics, reactive species, and artificial sweeteners, Dr. Lustig connects the biochemical dots to the brain, explaining how the amygdala functions like an ...
Send us a text In this episode of Decoding Health, we examine a recent shift in CDC guidance regarding hepatitis B vaccination recommendations for newborns. Long criticized for lagging behind evolving science, the CDC has now revised its position after reviewing updated risk-benefit data presented during a publicly broadcast panel discussion. Sparked by the birth of the host’s second grandchild, the conversation breaks down how hepatitis B is transmitted, why infection risk for infants born t...
Send us a text This episode featuring Dana Swope explores the intersection of nutrition, movement, stress, and metabolic health through an open, thought-provoking conversation. The discussion highlights how prioritizing protein and whole foods can reduce overall calorie needs while significantly increasing satiety, signaling a meaningful shift in how we approach sustainable nutrition. The episode also addresses the critical role stress plays in weight loss, reinforcing that meaningful fat los...
Send us a text This episode breaks down the Amylase test and its critical role in digestion, metabolic health, and personalized nutrition. The conversation explores how amylase activity impacts carbohydrate processing, energy levels, and blood sugar response, highlighting why a one-size-fits-all approach to diet does not work. Listeners learn how simple indicators like taste response and timing windows can reveal enzyme efficiency, when to pull back on certain carbs, and what low amylase acti...
Send us a text In this episode of Decoding Health, Dr. Urban A. Kiernan is joined by Dr. Don Clum for an in-depth, science-driven discussion on fasting, insulin regulation, and metabolic health—cutting through popular misconceptions to explain what fasting actually is and how it impacts the body. The conversation begins with how early insulin research led to modern fasting protocols and clarifies the difference between time-restricted eating, intermittent fasting, and true fasting. Dr. Clum e...
Send us a text In this episode of Decoding Health, Dr. Urban A. Kiernan breaks down the science behind vaccine adjuvants—what they are, why they are used, and how they influence immune responses. Drawing from his experience in biotechnology and pharmaceutical research, he explains how adjuvants enhance antibody production and increase the body’s overall biological workload. We explore commonly used compounds such as aluminum salts and newer immune-stimulating agents, while examining concerns ...
Send us a text In this episode, Dr. Evan Nadler challenges some of the most common misconceptions surrounding childhood and adolescent obesity—starting with the idea that it’s simply a result of poor diet or lack of willpower. Drawing on more than two decades of clinical, surgical, and research experience, he explains why obesity is a chronic disease, why BMI is an unreliable diagnostic tool, and how true risk should be assessed based on physical and mental health impact. The conversation exp...
Send us a text What are the real side effects of Vyleesi—and how do they compare to Viagra? In this follow-up conversation, Dr. Urban A. Kiernan breaks down what Vyleesi (also known as PT-141) is, how it works, and why it’s being discussed as a modern option for women experiencing low sexual desire, arousal challenges, or vaginal dryness (when prescribed for specific diagnoses). You’ll learn how Vyleesi’s mechanism differs from Viagra’s nitric-oxide-driven vasodilation, why Vyleesi is deliver...
Send us a text Michal Ofer shares the personal turning point that reshaped her entire approach to health—going from taking 30 pills a day at 35 to stepping away from medications and focusing on root-cause inputs that actually move the needle. She breaks down how diet directly affects stress tolerance, which foods tend to be most inflammatory, and why food quality can feel dramatically different across countries (and even compared to earlier eras in the U.S.). The conversation also compares he...
Send us a text In this holiday quick-hit episode of Decoding Health, Dr. Urban A. Kiernan sits down with Leila Adnani (PS Creative Studios) to close out 2025 and set the tone for a stronger 2026—without the fake “new year, new me” hype. Leila shares what PS Creative Studios is focused on heading into the new year, including a strategic reset around what to keep, what to cut, and what to build in 2026. The conversation turns into a practical take on why most New Year’s resolutions fail, how to...
Send us a text This Decoding Health episode follows the real-time journey of Keiran Meekins, a young athlete living with spastic diplegia cerebral palsy, as he undergoes an integrated evaluation and treatment process combining advanced physical therapy and emerging V-cell therapy. Recorded on location in Arizona, the episode brings listeners inside a full clinical assessment, gait analysis, neurological measurements, and post-treatment movement improvements. Through candid conversations with ...
Send us a text This episode examines the complex relationship between cholesterol, statin use, and Parkinson’s disease through a data-informed and critically minded discussion. The conversation challenges common assumptions about cholesterol suppression, exploring how statins can interfere with the body’s natural cholesterol production and why that matters for brain and neurological health. The episode addresses heart attack statistics in context, encouraging listeners to move beyond fear-bas...
Send us a text Gary Jackson joins Dr. Urban to unpack how discipline, mindset, and behavior patterns shape metabolic health. They explore why today’s “normal” encourages unhealthy habits, how marketing drives cravings, why the word “treat” programs reward behavior early in life, and how simple tools like label-reading can shift daily decisions. Gary shares the core coaching principles he teaches in judo—structure, repetition, accountability, and identity—and explains why sustainable cha...
Send us a text The internet is buzzing about “GLP-3,” but according to Dr. Urban, it doesn’t exist. In this episode, he breaks down why GLP-3 is nothing more than a marketing term tied to a still-experimental drug from Eli Lilly. Dr. Urban explains the real science behind GLP-1 and GLP-2, how these hormones naturally function in the body, and why the new triple-agonist compound being called “GLP-3” is not approved, not regulated, and absolutely not safe for consumer use. The conversation expo...
Send us a text Modern medicine is facing a crisis — and Dr. Ankur Verma is sounding the alarm. In this groundbreaking episode, Dr. Urban Kiernan sits down with Dr. Verma, who reveals why 95% of his patients show metabolic symptoms… and why questioning the system nearly got him ostracized by his own peers. This conversation exposes the cultural, political, and scientific forces shaping global nutrition — especially in India, where the debate around meat, health, and morality runs deep. Togethe...
Send us a text Tylenol is everywhere — in our homes, hospitals, and daily routines. But what do we actually know about it? In this eye-opening episode, Dr. Urban Kiernan breaks down the real science behind Tylenol (acetaminophen), how it differs from ibuprofen, and why its reputation for being “safe” deserves a closer look. We dive into: ⚠️ Why acetaminophen would fail modern clinical trial standards ⚠️ The truth behind NAPQI — the toxic byproduct no one talks about ⚠️ Why acetaminophen...
Send us a text What if your biggest health problems aren’t caused by food alone — but by light, biology, stress, and hidden environmental triggers no one warned you about? In this mind-shifting episode, Dr. Urban Kiernan and Shana Hussin dive deep into the overlooked science behind metabolic dysfunction, hormonal collapse, food sensitivities, and the quantum forces driving modern illness. Shana reveals her own journey through misunderstood symptoms, adrenal fatigue, and failed dietary a...
Send us a text Thanksgiving should fill you with gratitude — not glucose spikes, food crashes, and next-day regret. In this special episode, Dr. Urban Kiernan breaks down exactly how to enjoy the holiday without undoing all your metabolic progress. From pictures of his family (yes, including Stella!) to the science of satiety, Dr. Urban gives you a simple, realistic plan to survive Thanksgiving deliciously and wisely. Inside this episode, you’ll learn: 🔥 The exact eating strategy to sta...
Send us a text In this powerful and deeply human episode of Decoding Health, Dr. Urban Kiernan sits down with Dr. Kristina Dobyns, founder of Beyond Binge Eating — a groundbreaking integrative platform helping women break free from binge eating, food addiction, and the mind–body disconnect that fuels it. Dr. Dobyns opens up about her 20+ year battle with binge eating disorder, trauma, addiction, dissociation, and the personal rock-bottom that led her into residential treatment. From losing he...