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Defiant Health Radio with Dr. William Davis
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Defiant Health Radio with Dr. William Davis

Author: William Davis, MD

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William Davis, MD, cardiologist and author of the #1 New York Times bestselling Wheat Belly books, as well as Undoctored and, most recently, Super Gut, brings the unvarnished truth about many health conditions. So much information in health is crafted by industry, bent to the benefit of healthcare systems, delivered by willfully ignorant physicians. Yet a critical mass of truly useful, safe, effective health information has been reached--but someone has to deliver it to you. That is Dr. Davis' intention. Among the topics the Defiant Health Podcast covers are:--Microbiome health--The key to so many health conditions, as well as preservation of youth and vigor, can be found in the microbiome.--Heart health--You will find no mention of cholesterol or statin drugs here, only hard-hitting, science-based insights.--Thyroid health--Why do endocrinologists and other doctors get thyroid health so wrong? Let's get it right.--Weight loss--We don't count calories, don't push the plate away, or echo other ineffective knuckle headed solutions that have created the most overweight population of humans in history.--How to get rid of type 2 diabetes--it's painfully easy. --Get on the road to reversing autoimmune diseases--Take steps today to prevent neurodegenerative diseases such as Alzheimer's dementia, Parkinsonism, and multiple sclerosis--And many others.For more information on Dr. Davis' insights and programs, seeWheat Belly books--esp. the Wheat Belly Revised & Expanded Edition, 2019Wheat Belly 30-Minute CookbookWheat Belly 10-Day Grain DetoxUndoctored: Why Health Care Has Failed You and How You Can Become Smarter Than Your DoctorWheat Belly Blog: www.wheatbellyblog.comTalk to me through my membership website, the Undoctored Inner Circle:InnerCircle.Undoctored.com
140 Episodes
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People who were previously ravenously hungry, struggling to be satisfied and tending to overeat, can find themselves miraculously back in control of appetite just by adopting a number of basic dietary strategies that begin with elimination of gliadin-derived opioid peptides that come from the partial digestion of wheat and grains. Add a handful of other strategies and you will be freed from abnormal and perverse appetite stimulation that comes from consumption of several foods, nonsensi...
There is a non-infectious epidemic occurring right beneath our noses. The likelihood that you are affected is around 50%. It's the epidemic of small intestinal bacterial overgrowth, or SIBO. In this episode of Defiant Health, I run through the rationale that reveals that, even conservatively estimated, more than 100 million Americans have this condition. Because of the natural permeability of the small intestine designed for nutrient absorption, invading fecal microbes that have ascended fro...
My original recipe for SIBO Yogurt included three microbes chosen for their ability to colonize or germinate in the small intestine and produce bacteriocins, natural peptide antibiotics effective in killing the species of SIBO. The original formulation therefore specified L. reuteri, L. gasseri, and B. coagulans. However, B. coagulans proved to be unreliable in generating the high microbial counts we desire to overcome the trillions of invading fecal microbial species of SIBO. I therefo...
I’ve personally struggled with insomnia for years, unable to sleep more than a few hours at a time, experiencing frequent awakenings, sometimes awakening at 3 or 4 in the morning and unable to get back to sleep. And I tried almost everything short of prescription sedatives: tryptophan, 5-HTP, megadose melatonin, GABA, theanine, the antihistamine diphenhydramine, self-hypnosis, YouTube videos that claim to help you sleep within minutes. The few that worked left me feeling drugged the next day ...
Misplaced blame

Misplaced blame

2025-08-2817:35

You’re walking down the street, minding your own business, just out to run some errands. You’re wearing a black jacket, running shoes, a baseball cap. You pass the doors of a bank. Suddenly, the bank’s doors fly open and a man runs out, a man wearing a black jacket and a baseball cap. You see him running at top speed, disappearing around a corner. Moments later, two policemen burst through the bank’s doors, spot you, roughly spin you around, handcuff and arrest you. It’s a clear case of...
Microbiome Madness

Microbiome Madness

2025-08-1714:46

It’s truly an exciting time. The information and science surrounding the microbiome is exploding. It seems that a day doesn’t pass without some new, interesting insight emerges on microbiome questions, providing us with unprecedented insights and strategies to get better control over health, weight management, aging, etc. Look at what we are accomplishing, for example, with our cultivation of L. reuteri and L. crispatus. But it also means that misinformation, misinterpretation, an...
When the first Wheat Belly book was released in 2011, it quickly leapt to centerstage, gaining a huge worldwide following. Millions of copies of the book were sold in 37 countries, the conversation was featured in major media from network news to Dr. Oz to . I don’t believe that this was due to my personal charm or charisma, but because it worked: people experienced unexpected and substantial health and weight loss benefits even if such things had eluded them for years. Well, over those...
While CT heart scans are becoming increasingly popular to generate a coronary calcium score as a gauge of coronary atherosclerotic plaque and thereby risk for heart attack, there is actually a treasure trove of other useful information provided by the scan—but often not reported to you. In this episode of the Defiant Health podcast, I therefore help make you aware of the wealth of information provided by a CT heart scan that can empower you further in maintaining health and preventing h...
Inulin is a common fiber, the fiber found in root vegetables like onions, garlic, shallots, asparagus, jicama and many other foods. Humans lack the digestive enzymes, however, for metabolizing inulin, but microbes living in your gastrointestinal track are able to metabolize it. When beneficial microbes metabolize inulin, they convert it to fatty acids with numerous beneficial effects on gastrointestinal, brain, and metabolic health. But, when undesirable microbes metabolize inulin, bad things...
The Guardrails of Diet

The Guardrails of Diet

2025-06-2420:011

Here are what I call "The Guardrails of Diet,' i.e.., metabolic markers that tell you whether your diet is genuinely healthy or not. Too many people put too much stock in either a single marker like blood glucose, or the wrong marker like LDL cholesterol that takes you down the path of health disruptions: weight gain, visceral fat expansion, protein glycation, insulin resistance, formation of VLDL particles, cause you to rely on unhealthy foods, even increased risk for heart disease and other...
Conventional healthcare and dietary advice are, unfortunately, virtually useless in providing effective strategies on how to manage blood pressure naturally and nutritionally. They have, for instance, the DASH diet that can reduce systolic and diastolic blood pressure by a few millimeters but not more. They provide bland advice like lose weight or move more. Yet there are effective strategies that you can adopt that powerfully reduce and typically normalize blood pressure. Such strategies may...
Small intestinal bacterial overgrowth, or SIBO, is now rampant, a virtual nationwide epidemic, a condition now carried by around 50% of the population. If you have food intolerances, fibromyalgia, restless leg syndrome, are overweight or obese, have irritable bowel syndrome, an autoimmune condition, atrial fibrillation or numerous other common conditions, it is highly likely that SIBO is either the original cause or at least an exacerbating factor. You can take all the antiinflammatory drugs,...
Bakers, breadlovers, even purported health information authorities such as the Mayo Clinic all spread the claim that all the problems associated with consumption of foods made of wheat are eliminated or significantly reduced by sourdough fermentation. Is this true? In this episode of the Defiant Health podcast, Let’s take each of those claims made, one by one, and examine the evidence to see if there is any truth behind them. _____________________________________________________________...
We’ve been urged to include plenty of dietary fiber in our daily routines, fibers that come from vegetables, legumes, grains and other plant sources. But there is an animal-sourced fiber that has nearly disappeared from the modern human diet: hyaluronic acid. Hyluronic acid has nearly disappeared from the diet because it is primarily sourced from animal products, especially organ meats like brain, skin, and tongue. But hyaluronic acid is a fiber crucial for the health of many human orga...
LDL cholesterol, apoprotein B, saturated fat, TMAO, statin cholesterol drugs: Over the last 40 years, we have been inundated with misguided advice on how to reduce your risk for coronary heart disease, i.e., risk for such things as heart attack, need for heart procedures such as stent implantation or bypass surgery, or sudden cardiac death, serious and often life-threatening events. Has it worked? 80 million Americans now take statin drugs to reduce cholesterol yet there has been no meaningfu...
Go to any supermarket and you will see the impressive variety of products in the dairy aisle labeled "yogurt." You have a mindboggling collection of choices: non-fat, low-fat, full-fat, flavored, unflavored. Single-serve cartons, quart containers, squeezable tubes, jars. Will consuming any of these products change your life in any significant way? Will you be heathier, have better bowel health, skin health, metabolic health, mental health? Let’s discuss why, no, you will not experience ...
The practice of immersing your body in ice water is growing in popularity based on claims of improved mood and well-being, muscle recovery after exercise, even longevity. But this ignores the well-established fact that sudden cardiac death is a real risk due to coronary spasm, causing heart attack, and unstable heart rhythms due to a situation called autonomic conflict. There are a growing number of lawsuits that have been filed for the many sudden cardiac deaths that have occurred. So let’s ...
Over 50% of Americans are, at any one time, trying to lose weight. So it’s understandable that the GLP-1 agonist drugs like Ozempic and Mounjaro have become so popular, given their spectacular upfront results. Others have used reduced calorie diets in their various forms: counting points, assigning foods red, yellow, or green lights, meal replacement products, etc. Or bariatric procedures like lap-band, jejunoileal bypass, or gastric bypass. But there is a lot that people are not told about t...
I first met Dr. Eric Westman at a low-carbohydrate meeting a number of years ago where he discussed an extremely important and insightful human clinical trial he had conducted in which he counseled participants with type 2 diabetes to follow a very low-carbohydrate, essentially ketogenic, diet. He was almost prohibited from conducted the study because some colleagues felt it was too dangerous. Nonetheless, the study was completed and demonstrated that type 2 diabetic participants no longer ne...
We all recognize that American healthcare is a badly broken system. Wildly overpriced, exploitative, with a focus on pharmaceuticals and medical procedures to the exclusion of basic issues such as nutrition, the role of nutrients, and the microbiome. Can we expect doctors, healthcare executives, pharma or medical device executives to find better solutions? I highly doubt it. One of the problems plaguing conventional delivery of healthcare is that doctors lack the time, knowledge, and fr...
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