Dementia Researcher

This festive special flips the script on polished papers and perfect protocols. Dr Fiona McLean is joined by Dr Ian Harrison, Dr Soraya Meftah, and Dr Kate Harris to share the research moments that did not go to plan but taught them far more than success ever could. From ELISAs gone rogue and antibodies that refuse to behave, to admin systems that quietly derail months of planning, this episode is a reminder that real research is messy, unpredictable, and occasionally hilarious. The conversation moves easily between lab disasters, student supervision realities, near misses with fire, and the emotional rollercoaster of academic life. It is light hearted, reassuring, and (hopefully) relatable. A permission slip to laugh, reflect, and remember that being wrong is often part of doing good science. Merry Christmas from all of us! -- Top takeaways - Most experiments do not fail, they redirect - Unexpected results often open better research questions - Rushing protocols almost always backfires - Admin failures can be as stressful as lab failures - Talking openly about what went wrong saves time and money - Students learn more from troubleshooting than from perfect results - Publishing negative findings can help an entire field - Being wrong is built into the scientific method - Giving yourself time and mental space matters - If no one was hurt, it is probably recoverable A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk -- Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://www.bsky.app/profile/dementiare…archer.bsky.social -- Download and Register with our Community App: https://www.onelink.to/dementiaresearcher -- Chapters 00:00 Introduction to Research Fails 02:07 Learning from Mistakes in Research 04:53 Unexpected Outcomes and Their Value 05:53 The Importance of Data in Research 08:38 Navigating Challenges in Experiments 11:33 The Role of Collaboration in Research 14:40 Discovering New Avenues from Failures 15:40 The Importance of Literature in Research 16:41 Experiences of Discovery and Optimization in Research 17:51 Near-Death Experiences in the Lab 19:34 Lessons from Lab Mishaps 20:57 Administrative Chaos in Research 26:52 The Culture of Silence Around Research Failures 33:16 Navigating Criticism and Feedback in Academia 36:51 Navigating Experimental Challenges 38:43 The Temptation of Over-Experimenting 40:03 Learning from ELISA Mishaps

This festive charity debate asks a question nobody saw coming but everyone had an opinion on. Would Santa Claus make a good principal investigator? Recorded live in the Dementia Researcher Community, this Christmas special brings humour, sharp thinking, and real reflections on leadership, research culture, ethics, and academia. -- The debate is hosted by Adam Smith and Dr Anna Volkmer. Speaking for the motion is Rebecca Williams, PhD researcher exploring FTD and apathy. Speaking against the motion is Dr Connor Richardson, Research Fellow working in data science, epidemiology, and machine learning in dementia research. Through opening statements, rebuttals, and audience questions, the discussion ranges from logistics and mentorship to ethics, transparency, wellbeing, and what good leadership really looks like in research. While lighthearted on the surface, the debate reveals some very familiar academic tensions beneath the tinsel. Vote now: 🎅 https://8k3qel8nuxc.typeform.com/to/tXVIkWRe -- This episode was recorded as a charity event in support of Dementia UK and their Admiral Nurses, who provide vital support to people living with dementia and their families, especially during the Christmas period. If you enjoyed the debate and would like to support their work, you can donate here: 👉 https://buy.stripe.com/28EfZj1G37zIcrF2wA77O00 Thank you for listening, watching, and supporting dementia research and care. -- Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://www.bsky.app/profile/dementiare…archer.bsky.social -- Download and Register with our Community App: https://www.onelink.to/dementiaresearcher -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of Santa Clause, The North Pole or Dementia Research.

In this episode of the Dementia Researcher podcast we look at how dementia clinical trials reach far beyond medicines. Host Dr Annalise Rahman Filipiak speaks with Dr Elizabeth Rhodus, Dr Inga Antonsdottir, and Dr Elisa França Resende about entering the field, working with behavioural and community based interventions, and learning the skills needed to deliver rigorous, reproducible studies that still respect the individual needs of participants. The guests discuss their routes into trials, what surprised them, what they wish they had known earlier, and how mentorship and collaboration shaped their progress. They touch on trial design, regulatory processes, cultural considerations, and the value of early career networks that support researchers across different countries. -- Topics covered 🔹What early career researchers find challenging about trial methods 🔹Working in homes and communities 🔹Designing sensory and environmental interventions 🔹Literacy based trials in Brazil and issues of inclusion 🔹Mentorship, networks and training programmes 🔹Trial rigour, manuals, assessments and reproducibility 🔹Regulatory hurdles and timeframes 🔹Practical advice for researchers wanting to deliver a trial as part of their research -- Find more information on our guests, and a full transcript of this podcast on our website at: https://www.dementiaresearcher.nihr.ac.uk/podcast -- Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://www.bsky.app/profile/dementiare…archer.bsky.social -- Download and Register with our Community App: https://www.onelink.to/dementiaresearcher -- Chapters 00:00 Introduction to Dementia Research and Clinical Trials 05:01 Early Career Researchers in Clinical Trials 11:31 The Role of Mentorship in Research 18:46 Innovative Interventions Beyond Pharmacology 25:41 Community Engagement and Methodological Considerations 33:32 Overcoming Barriers in Clinical Trials 38:22 Advice for Aspiring Clinical Trialists 41:00 Whimsical Research Questions and Closing Thoughts #dementiaresearch #methodology #dementia #ClinicalTrials @alzassociation #ISTAART

In this episode of the Dementia Researcher - Xxplored Women’s Brain Health podcast, host Dr Laura Stankeviciute speaks with Professor Claudia Barth from Charite University and Dr Gillian Coughlan from Harvard Medical School to examine the midlife transition, menopause and its significance for women’s brain health. Together they outline what the menopause truly involves across the early, late, and post stages, and explain how hormonal change affects brain structure, energy use, mood, and cognition. They also explore why this period may coincide with greater vulnerability to later Alzheimer’s disease and discuss the role of early or surgical menopause, symptom severity, and gaps in existing research cohorts. The episode highlights the need for richer reproductive data, real time biomarker studies, and closer collaboration with digital health tools to better capture women’s lived experiences. It reflects a growing wave of research and public interest aimed at improving understanding, support, and evidence based care during this important life stage. -- Takeaways ● Menopause is a long transition shaped by fluctuating hormones. ● Cognitive and mood symptoms reflect changes in brain networks. ● Earlier menopause is linked with increased later Alzheimer’s risk. ● Major research cohorts lack detailed reproductive data. ● New real time studies are beginning to track symptoms and biomarkers. ● Digital tools will be key for future research. ● Better global representation is needed across studies. ● Momentum is building to close long standing gaps in women’s health. -- Find bios on all our speakers, a full transcript of the show and more on our website at https://www.dementiaresearcher.nihr.ac.uk - Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://www.bsky.app/profile/dementiare…archer.bsky.social -- Download and Register with our Community App: https://www.onelink.to/dementiaresearcher -- Chapters 00:00 Introduction to Menopause and Research Focus 07:25 Understanding Menopause: Definitions and Stages 16:27 Menopause and Alzheimer's Disease: A Critical Connection 22:43 Understanding Menopause and Brain Health 25:21 Historical Blind Spots in Alzheimer's Research 26:38 The Importance of Reproductive Variables 31:46 Biomarkers and Methodologies in Women's Health Research 35:28 Industry Collaboration in Research 39:00 Personal Reflections on Women's Brain Health

In this episode, host Dr Anna Volkmer is joined by Dr Alys Griffiths, Sophie Jeffery, and Esther Whittlesea Reed to explore a two-year Alzheimer’s Society project testing #psychotherapy for people with dementia. Together, they discuss the importance of therapy in #dementia care, the barriers to access, the development of new therapist competencies, and the lived experience of psychotherapy from both clinical and personal perspectives. -- Takeaways 🔹Psychotherapy can provide meaningful outcomes for people with dementia. 🔹Barriers to accessing therapy include stigma and lack of understanding. 🔹Core competencies for therapists are essential for effective care. 🔹Family therapy is crucial for supporting families affected by dementia. 🔹Training for therapists should include specific skills for working with dementia patients. 🔹Research findings highlight the need for better communication about therapy options. 🔹The importance of lived experience in shaping research and therapy. 🔹Future research should focus on improving access to therapy for families. 🔹There is a need for a cultural shift in how dementia is perceived in therapy. -- Find more information on our guests, and a full transcript of this podcast on our website at: https://www.dementiaresearcher.nihr.ac.uk/podcast -- Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://www.bsky.app/profile/dementiare…archer.bsky.social -- Download and Register with our Community App: https://www.onelink.to/dementiaresearcher -- Chapters 00:00 Introduction and Project Overview 04:40 Background and Rationale for Psychotherapy in Dementia 09:20 Personal Experiences and Expectations of Therapy 13:52 Study Design and Methodology 18:33 Roles and Contributions of the Research Team 23:16 Collaborative Insights from Lived Experience 24:42 Key Findings on Psychotherapy for Dementia 27:58 Core Competencies for Therapists 31:45 Understanding Dementia as a Traumatic Life Event 34:46 Future Directions in Dementia Research 40:21 Advocating for Comprehensive Support in Dementia Care

In this episode of the Dementia Researcher Podcast, host Dr Anna Volkmer, Associate Professor at UCL and Speech and Language Therapist explores the experiences of young carers in families affected by dementia, the challenges they face, the support they receive, and what more could and should be done. Anna is joined by Dr Patricia Masterson Algar a Lecturer at Bangor University, leading new research funded by Health and Care Research Wales to develop a peer support programme for young carers. Hannah Gardner a Consultant Admiral Nurse for Children and Young People at Dementia UK, advocating nationally for better awareness and support and Gareth and Euan Heslop, father and son who share their lived experience of caring for a wife and mother with young-onset dementia. Together they discuss the often overlooked impact of dementia on children and teenagers, the stigma and isolation young carers face, and how families, schools, and professionals can work together to provide better understanding and support. -- In this episode: • The hidden realities of growing up as a young carer. • Stigma, awareness, and the importance of talking openly about dementia. • How schools and communities can recognise and support young carers. • Why services must consider the whole family, not just the person diagnosed. • The role of peer support and what new research hopes to achieve. • Voices from lived experience — what young carers really need. 🎧 Listen to hear how families, researchers, and practitioners are working together to ensure young carers are seen, heard, and supported. -- The study discussed in the podcast is now open to recruitment. If you live in England or Wales and are aged 11-16 and involved in the care of someone living with dementia get in touch p.m.algar@bangor.ac.uk -- Find more information on our guests, and a full transcript of this podcast on our website at: https://www.dementiaresearcher.nihr.ac.uk/podcast -- Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://www.bsky.app/profile/dementiare…archer.bsky.social -- Download and Register with our Community App: https://www.onelink.to/dementiaresearcher

In our first episode of the XXplored Women's Brain Health podcast, our resident expert and host Dr Laura Stankeviciute from University of Gothenburg engages with leading neuroscientists Professor Liisa Galea from University of Toronto and Dr Maria Teresa Ferretti from Karolinska Institutet to explore the critical intersection of sex, gender, and brain health. Together our guests discuss their personal journeys into neuroscience, the biological differences in brain health, the impact of hormonal changes, and the vulnerability of women to Alzheimer's disease. The conversation also addresses the barriers to inclusion in clinical research, the implications of neurosexism, and the importance of precision medicine. The episode emphasises the need for early diagnosis and the societal stigma surrounding women's health issues, while advocating for a more inclusive and evidence-based approach to brain health research and treatment. This first show sets the scene for what will be an ongoing series of shows, delivered within the Dementia Researcher podcast. Takeaways ● Sex differences shape the brain at every level – structure, hormones, immunity, and function. ● Menopause is a key vulnerability window for women’s brain ageing and Alzheimer’s risk. ● Women face higher Alzheimer’s prevalence, not just because they live longer. ● Women were excluded from trials for decades, leaving dangerous gaps in knowledge. ● Fear of neurosexism and misunderstandings of feminism slowed progress. ● Precision medicine must include sex and gender or risk missing early diagnoses. ● Research funding and clinical guidelines lag far behind need. ● Momentum is building: younger researchers and public interest are pushing change. ● Core message: Different ≠ inferior. Diversity drives discovery. -- Find more information on our guests, and a full transcript of this podcast on our website at: https://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of University College London, Dementia Researcher or its funders. -- Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://www.bsky.app/profile/dementiare…archer.bsky.social -- Download and Register with our Community App: https://www.onelink.to/dementiaresearcher

In this episode of the Dementia Researcher Podcast, host Adam Smith (Programme Director at UCL) is joined by Dr Sam Moxon, Dr Lindsey Sinclair, and Dr Ece Bayram to explore the art of delivering lightning talks. Together they share practical advice on structuring short presentations, handling nerves, designing impactful slides, and engaging diverse audiences. With personal anecdotes and strategies from their own conference experiences, this discussion offers valuable guidance for early career researchers preparing to present their work with clarity and confidence. -- Takeaways • Lightning talks are concise presentations, usually under five minutes. • Strong preparation is essential for success. • An engaging delivery leaves a lasting impression. • Slides should support the message, not overwhelm it. • Rehearse to the clock to stay on time. • Personal touches help connect with the audience. • Focus on one key message instead of overloading with detail. • Use clear, accessible language throughout. • Treat the format as a teaser that sparks curiosity. • Lightning talks are excellent opportunities for early career researchers. -- If you would like to deliver a lightning talk at the ARUK Conference or AAIC Neuroscience Next Conference in February 2026 – get your abstracts submitted by October 22nd 2025. https://www.alzheimersresearchuk.org/research/for-researchers/research-conference/abstracts-2026 https://www.dementiaresearcher.nihr.ac.uk/aaic-neuroscience-next-2026-manchester-uk/ -- Find more information on our guests, and a full transcript of this podcast on our website at: https://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association. -- Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://www.bsky.app/profile/dementiare…archer.bsky.social -- Download and Register with our Community App: https://www.onelink.to/dementiaresearcher

In this episode of the Dementia Researcher podcast, host Adam Smith discusses the upcoming AAIC Neuroscience Next Conference with guests Tricia Nicholson, Dr Amanda Heslgrave, and Kalli Mavromati. They explore the unique hybrid format of the conference, which combines in-person and virtual elements, making it accessible to a global audience. The conversation highlights the focus on biomarkers in dementia research, the importance of early career researchers, and the abstract submission process, providing valuable tips for potential presenters. The episode emphasizes the conference's goal of fostering collaboration and sharing knowledge within the dementia research community. Register to attend: https://www.alz.org/neurosciencenext/overview.asp -- Takeaways: • The AAIC Neuroscience Next Conference is free and accessible to all. Taking place across 6 countries and online from the 23rd to 26th February 2026. • The UK hub will focus on biomarker advancements in dementia diagnosis, with a full in-person conference on the 26th February. • The conference aims to support early career researchers in dementia research. • A unique hybrid format allows for both in-person and virtual participation. • Abstract submissions open on September 22nd and are encouraged from all researchers. From basic science to dementia care. • The UK Hub is particularly keen for researchers to submit abstract in biomarker domains. o Fluid Biomarkers o Cognitive Assessments o Physiological and Behavioural Biomarkers o Neuroimaging o Technology Biomarkers -- For more information on the global event visit: https://www.alz.org/neurosciencenext/overview.asp For information on the UK Hub visit: https://www.dementiaresearcher.nihr.ac.uk/aaic-neuroscience-next-2026-manchester-uk/ -- Find more information on our guests, and a full transcript of this podcast on our website at: https://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of University College London, Dementia Researcher or its funders. -- Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://www.bsky.app/profile/dementiare…archer.bsky.social -- Download and Register with our Community App: https://www.onelink.to/dementiaresearcher

In this episode we welcome three GBHI Fellows: guest host and filmmaker Michelle Memran, documentary photographer Alex Kornhuber, and social sciences academic Dr Sonata Mačiulskytė. Together they explore the ways in which caregiving, creativity, and change come together in the context of dementia. Drawing on their experiences of supporting loved ones with dementia, they reflect on how these personal journeys have influenced their professional work and shaped their understanding of the disease. The discussion touches on the early signs of dementia, the transformation of relationships through caregiving, and the importance of early diagnosis. The conversation also considers the significance of documenting caregiving experiences and the need to reshape the narrative around dementia. By sharing stories and creative perspectives, the guests highlight how shifting this narrative can foster greater awareness, empathy, and understanding. -- Takeaways • Caregiving is a deeply personal journey that shapes professional work. • Recognising early signs of dementia can be challenging but crucial. • Relationships with loved ones can transform through the caregiving experience. • Early diagnosis can lead to better care and understanding. • Documenting caregiving experiences can foster connection and awareness. • Language and narrative around dementia need to change for better understanding. • Sharing personal stories can help others feel less alone in their caregiving journey. • The experience of dementia is unique to each individual and family. • Advocacy for brain health should start early in life. For more information on the Atlantic Fellows for Equity in Brain Health Program visit: https://www.gbhi.org/ -- Find more information on our guests, and a full transcript of this podcast on our website at: https://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association. -- Follow us on Social Media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://www.bsky.app/profile/dementiaresearcher.bsky.social -- Download and Register with our Community App: https://www.onelink.to/dementiaresearcher

Grant rejection is part of every researcher’s journey — and it never stops, no matter your career stage. In this episode of the Dementia Researcher Podcast, host Dr Fiona McLean (Alzheimer’s Research UK Fellow at the University of Dundee, studying links between metabolic syndrome, learning and memory) speaks with: -- Dr Sarah Marzi — Senior Lecturer at King’s College London and UK DRI group leader, researching the epigenome in neurodegenerative diseases. Dr Kate Harris — Research Fellow at Newcastle University, soon to be Senior Lecturer, specialising in drug discovery for neurodegenerative diseases. Dr Dayne Beccano-Kelly — UK DRI Future Leader Fellow and group leader at Cardiff University, focusing on synaptic dysfunction in Parkinson’s disease. Together they share personal experiences of failed applications, from crushing first rejections to the resilience that comes with time, blending honest stories with practical strategies. -- In this episode: 💬 First-hand stories of fellowship and project grant rejections 📝 How to use reviewer feedback — even when it’s unhelpful ✍️ Why writing style and clarity can change your funding chances 🎯 Choosing funders whose remit truly fits your work 🍦 Coping strategies, from ice cream to badminton to music 💪 Building resilience and knowing when to rework or drop an idea 🤝 The value of mentors, networks and peer support 🎧 Listen to learn why rejection isn’t the end — and how it can be the start of a better grant. -- Find more information on our guests, and a full transcript of this podcast on our website at: http://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association. -- Follow us on Social Media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://bsky.app/profile/dementiaresearcher.bsky.social -- Download and Register with our Community App: https://onelink.to/dementiaresearcher

In this podcast we share a few selected highlights from the Alzheimer’s Association International Conference (AAIC) day two and day three of the main event in Toronto and Online, 27the - 31st July. -- Dr Shea Andrews, Assistant Professor at University of California San Francisco hosts the show with special guests: Dr Joe Butler, NIHR ARC Research Fellow at University of Sunderland Dr Lindsey Sinclair, Clinical Research Fellow & Consultant in Old Age Psychiatrist at University of Bristol Dr Harriet Demnitz-King, Post-doctoral Research Fellow at Queen Mary University of London -- The AAIC brings together distinguished basic scientists, clinical researchers, early career investigators, clinicians and the care research community at the largest and most influential international conference on dementia science. They share theories and breakthroughs while exploring opportunities to accelerate work and elevate careers. Main plenary talks from the day came from Professor Sharon Naismith from University of Sydney, Australia giving a talk titled "Waking Up to the Importance of Sleep in MCI and AD" and Professor Katrin Andreasson, M.D. with a talk titled "Restoring Hippocampal Glucose Metabolism Rescues Cognition Across Alzheimer’s Disease Pathologies". -- Find more information on our guests, and a full transcript of this podcast on our website at: https://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

In this podcast we share a few selected highlights from the Alzheimer’s Association International Conference (AAIC) day two and day three of the main event in Toronto and Online, 27the - 31st July. -- Dr Connor Richardson, NIHR / Alzheimer's Society Dem Comm Research Fellow from University of Newcastle hosts the show with special guests: Sára Zsadányi, PhD Student at Sant Pau Memory Unit – Neuroimaging Core and Universitat Autonoma de Barcelona Dr Tatiana Giovannucci, Alzheimer's Association Research Fellow Dr Richard Oakley, Associate Director of Research at Alzheimer's Society The AAIC brings together distinguished basic scientists, clinical researchers, early career investigators, clinicians and the care research community at the largest and most influential international conference on dementia science. They share theories and breakthroughs while exploring opportunities to accelerate work and elevate careers. -- Main plenary talks from the day came from Professor Inhee Mook-Jung Seoul National University, Korea with a talk titled "The Gut-Brain Axis in Alzheimer’s Disease: Unraveling Pathogenesis and Exploring Novel Therapeutic Strategies" and Dr Juan Fortea, Memory Unit Director — Hospital de la Santa Creu i Sant Pau, Spain with a talk titled "Alzheimer’s Disease in Down Syndrome". @alzassociation #aaic25 #aaic -- Find more information on our guests, and a full transcript of this podcast on our website at: https://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

In this podcast we share a few selected highlights from the Alzheimer’s Association International Conference (AAIC) first and second day of the main event in Toronto and Online, 27the - 31st July. -- Dr James Brady, Postdoctoral Research Fellow at University of Tasmania hosts the show with special guests: Dr Lucy Stirland, Academic Old Age Psychiatrist at The University of Edinburgh Dr Isabel Castanho, Instructor at the Beth Israel Deaconess Medical Center (BIDMC), Harvard Medical School Felix Wittmann, Research Fellow & PhD candidate at Leipzig University -- The AAIC brings together distinguished basic scientists, clinical researchers, early career investigators, clinicians and the care research community at the largest and most influential international conference on dementia science. They share theories and breakthroughs while exploring opportunities to accelerate work and elevate careers. Main plenary talks from the day came from Professor Katerina Akassoglou, University of California, San Francisco, United States exploring Neurovascular Interactions in Alzheimer’s Disease: From Mechanisms to Treatments + Professor Maria Grazia Spillantini, from University of Cambridge United Kingdom for her plenary titled 'The Multiple Facets of Tau Pathology'. -- #AAIC25 @alzassociation -- Find more information on our guests, and a full transcript of this podcast on our website at: https://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

In this podcast we share a few selected highlights from the Alzheimer’s Association International Conference (AAIC) pre-conference and first day of the main event in Toronto and Online, 27the - 31st July. -- Dr Tamlyn Watermeyer hosts the show with special guests: Dr Emily Ho, Assistant Professor at Northwestern University Dr Laura Stankeviciute, Postdoctoral Researcher & Scientific Project Manager at University of Gothenburg Joseph Russell, NIHR Research Assistant at Northumbria University -- The AAIC brings together distinguished basic scientists, clinical researchers, early career investigators, clinicians and the care research community at the largest and most influential international conference on dementia science. They share theories and breakthroughs while exploring opportunities to accelerate work and elevate careers. Main plenary talk from the day came from Sylvia Villeneuve, Ph.D. Associate Professor, Department of Psychiatry — McGill University, Canada talk about Biomarker and Clinical Trajectories of Preclinical AD. -- #AAIC25 @alzassociation -- Find more information on our guests, and a full transcript of this podcast on our website at: https://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

Welcome to the sixth season of the Dementia Researcher X ISTAART PIA Relay Podcast. This series features interviews with ISTAART PIA committee members talking about their research, the research landscape of their fields, and the work of the ISTAART Professional Interest Areas (PIA) they represent. As we build up to the Alzheimer’s Association International Conference in Toronto, join us for daily episodes that showcase the remarkable work being done in various research fields. -- In this Relay Podcast episode, Dr Colin Groot interviews Dr Marta Del Campo, Head Fluid Biomarker Facility; Ramón y Cajal Research fellow at BarcelonaBeta Brain Research Center and chair of the ISTAART Biofluid Based Biomarkers PIA. Together, they talk about recent advances in fluid biomarkers in dementia research, and explore the growing role of plasma biomarkers, integration with clinical trials, challenges with reproducibility and diversity, and the promise of proteomics and AI. Marta also reflects on the work of ISTAART, their plans for AAIC, the value of publishing negative findings, and why ISTAART offers vital opportunities for early career researchers. -- The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 30 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between. To sign-up to ISTAART and a PIA visit: http://www.istaart.alz.org Note: ISTAART Membership is free for students worldwide, and for researchers of all levels based in Low- and Middle-Income Countries. -- To book your place at this year’s AAIC (In-person and online) visit: http://www.aaic.alz.org -- Find more information on our guests, and a full transcript of this podcast on our website at: http://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

Welcome to the sixth season of the Dementia Researcher X ISTAART PIA Relay Podcast. This series features interviews with ISTAART PIA committee members talking about their research, the research landscape of their fields, and the work of the ISTAART Professional Interest Areas (PIA) they represent. As we build up to the Alzheimer’s Association International Conference in Toronto, join us for daily episodes that showcase the remarkable work being done in various research fields. -- In this episode, Professor Owen Carmichael talks with Dr Shana Stites, Assistant Professor at University of Pennsylvania and Chair of the ISTAART Diversity and Disparities PIA. In this discussion they explore the importance of inclusive participation in dementia research, the challenges of equitable access to research and care, and the shift toward more community-engaged approaches. The conversation highlights barriers like limited access to healthcare, the ethics of stipends, and the value of transparency, reciprocity, and representation in Alzheimer's disease and related research. They also talk about the wider work and aims of the PIA and what they have planned for the upcoming AAIC. -- The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. -- There are currently 30 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between. To sign-up to ISTAART and a PIA visit: http://www.istaart.alz.org Note: ISTAART Membership is free for students worldwide, and for researchers of all levels based in Low- and Middle-Income Countries. -- To book your place at this year’s AAIC (In-person and online) visit: http://www.aaic.alz.org -- Find more information on our guests, and a full transcript of this podcast on our website at: http://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

Welcome to the sixth season of the Dementia Researcher X ISTAART PIA Relay Podcast. This series features interviews with ISTAART PIA committee members talking about their research, the research landscape of their fields, and the work of the ISTAART Professional Interest Areas (PIA) they represent. As we build up to the Alzheimer’s Association International Conference in Toronto, join us for daily episodes that showcase the remarkable work being done in various research fields. -- In this episode, Professor Natalie Phillips interviews Professor Owen Carmichael, Director of Biomedical Imaging at Pennington Biomedical Research Center and incoming chair of the iSTAART Nutrition, Metabolism, and Dementia PIA. Owen shares his journey from computer science to neuroscience, and how his imaging work investigates how diet and metabolism shape dementia risk. They explore the promise of precision nutrition, the challenges of studying lifelong dietary exposure, and the vital role of olfaction and sensory health in nutrition. The episode also discusses the importance of inclusive research and lifelong data to understand and prevent cognitive decline. The show rounds-up the PIAs upcoming work at the AAIC, and the work of the PIA. -- The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 30 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between. To sign-up to ISTAART and a PIA visit: http://www.istaart.alz.org Note: ISTAART Membership is free for students worldwide, and for researchers of all levels based in Low- and Middle-Income Countries. -- To book your place at this year’s AAIC (In-person and online) visit: http://www.aaic.alz.org -- Find more information on our guests, and a full transcript of this podcast on our website at: http://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

Welcome to the sixth season of the Dementia Researcher X ISTAART PIA Relay Podcast. This series features interviews with ISTAART PIA committee members talking about their research, the research landscape of their fields, and the work of the ISTAART Professional Interest Areas (PIA) they represent. As we build up to the Alzheimer’s Association International Conference in Toronto, join us for daily episodes that showcase the remarkable work being done in various research fields. -- In this episode, Dr Marta del Campo interviews Natalie Phillips, Chair of the Sensory Health and Cognition PIA and Professor of Psychology at Concordia University. Together, they discuss the role of hearing, vision, and olfaction in cognitive ageing and dementia risk. They explore mechanisms behind these links, from cognitive load to social isolation, and discuss emerging biomarker research, challenges in clinical implementation, and how this new ISTAART PIA is fostering interdisciplinary collaboration. The episode also previews upcoming activities at AAIC and highlights opportunities for early career researchers to get involved. -- The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. -- There are currently 30 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between. To sign-up to ISTAART and a PIA visit: http://www.istaart.alz.org Note: ISTAART Membership is free for students worldwide, and for researchers of all levels based in Low- and Middle-Income Countries. -- To book your place at this year’s AAIC (In-person and online) visit: http://www.aaic.alz.org -- Find more information on our guests, and a full transcript of this podcast on our website at: http://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

Welcome to the sixth season of the Dementia Researcher X ISTAART PIA Relay Podcast. This series features interviews with ISTAART PIA committee members talking about their research, the research landscape of their fields, and the work of the ISTAART Professional Interest Areas (PIA) they represent. As we build up to the Alzheimer’s Association International Conference in Toronto, join us for daily episodes that showcase the remarkable work being done in various research fields. -- In this Relay Podcast episode, Dr Colin Groot interviews Dr Marta Del Campo, Head Fluid Biomarker Facility; Ramón y Cajal Research fellow at BarcelonaBeta Brain Research Center and chair of the ISTAART Biofluid Based Biomarkers PIA. Together, they talk about recent advances in fluid biomarkers in dementia research, and explore the growing role of plasma biomarkers, integration with clinical trials, challenges with reproducibility and diversity, and the promise of proteomics and AI. Marta also reflects on the work of ISTAART, their plans for AAIC, the value of publishing negative findings, and why ISTAART offers vital opportunities for early career researchers. -- The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 30 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between. To sign-up to ISTAART and a PIA visit: http://www.istaart.alz.org Note: ISTAART Membership is free for students worldwide, and for researchers of all levels based in Low- and Middle-Income Countries. -- To book your place at this year’s AAIC (In-person and online) visit: http://www.aaic.alz.org -- Find more information on our guests, and a full transcript of this podcast on our website at: http://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.