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Dhru Purohit Show

Dhru Purohit Show
Author: Dhru Purohit
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© Dhru Purohit Show 2024
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Hi, I'm Dhru (like Drew), and every week, I interview the top experts in health, medicine, and mindset to provide you with in-depth, step-by-step protocols to take your health to the next level.
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This episode is brought to you by LMNT, Bon Charge, and Birch Living.
When we think of mitochondria, we often think of them as the powerhouse of the cell, but they do so much more. Mitochondria are responsible for intricate functions like detoxification, immune defense, and cell signaling. Their health is directly tied to our overall health.
Today on The Dhru Purohit Show, Dhru sits down with Dr. Daria Mochly-Rosen to discuss why protecting our mitochondria is essential for long-term health. Dr. Daria reveals the top insults that damage mitochondrial function, such as air pollution, pesticides, and chronic stress, and explains how they’re linked to conditions like Parkinson’s disease. She also shares her groundbreaking research on aldehyde dehydrogenase 2 and emphasizes why, in today’s world, our mitochondria are under constant attack, making it more important than ever to reduce these burdens on the body.
Dr. Daria Mochly-Rosen is the George D. Smith professor for translational medicine at Stanford University School of Medicine. She is passionate about turning scientific discoveries into real-world treatments and helping people make informed health choices. She has founded three biotech companies and created SPARK, a program that focuses on translating scientific innovations to benefit patients. Following the success of the program at Stanford, which led to the formation of over fifty biopharmaceutical companies, SPARK now operates in dozens of universities around the world.
In this episode, Dhru and Dr. Rosen dive into:
What’s really hurting your mitochondria today (1:20)
How air pollution, smoke and vaping chip away at your cells (2:40)
The hidden danger of pesticides (9:00)
Are we sensitive to electromagnetic frequencies? (17:55)
Radiation’s surprising effect on your cells (22:45)
The enzyme that could reveal your mitochondrial health (27:45)
Should you worry about everyday radiation? (36:21)
The control you do have over your health (41:51)
Light, sleep, and mitochondria: the photobiomodulation link (42:46)
Why chronic stress silently destroys mitochondria (47:16)
The connection between mitochondria and aging (51:58)
How exercise powers up your mitochondria (01:01:06)
The secret of pairing endurance with strength (1:09:15)
Fiber’s underrated role in mitochondrial health (1:14:21)
Also mentioned in this episode:
The Life Machines: How Taking Care of Your Mitochondria Can Transform Your Health
For more on Dr. Rosen, follow her on LinkedIn or visit her Website.
This episode is brought to you by LMNT, Bon Charge, and Birch Living.
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This episode is brought to you by Maui Nui and AquaTru.
Getting the right nutrients is essential. But in today’s world, more isn’t always better. From vitamins to organ meats, Chris Kresser breaks down what we actually need, what we’re missing, and where we might be overdoing it.
Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Chris Kresser. He explains how the body naturally processes nutrients from whole foods compared to the impact of over-supplementation in our modern world. Chris highlights the importance of vitamin D, K2, and magnesium, as well as the benefits of organ meats and concerns surrounding bioavailability.
Chris Kresser, M.S., L.Ac., is cofounder of the California Center for Functional Medicine, founder of the Kresser Institute, and host of the top-ranked podcast Revolution Health Radio. A New York Times bestselling author and one of the most respected voices in Functional Medicine and ancestral health, Chris has trained over 2,000 clinicians worldwide. He was named one of the 100 most influential people in health and fitness by Greatist and has appeared in major outlets like Time, The Atlantic, NPR, and Fox.
In this episode, Dhru and Chris dive into:
Which nutrients you can get too much of (1:57)
Optimal vitamin D levels and the risks of over-supplementation (4:07)
Vitamin K2 and magnesium in conjunction with vitamin D (11:01)
Nutrient-rich organ meats and tips for adding them to your diet (12:41)
Key nutrients missing from most diets (24:06)
Calcium and bioavailability (27:29)
Final thoughts (29:59)
Also mentioned:
Full episode with Chris Kresser
Try This: 3 Overhyped Supplements—And What to Take Instead
This episode is brought to you by Mau Nui and AquaTru.
Right now, Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products. Just go to mauinuivenison.com/dhru to secure your access now, but hurry, supply is limited!
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This episode is brought to you by BiOptimizers, Cozy Earth, and Fatty15.
While the “10,000 steps a day” idea came from a marketing company in Japan, that doesn’t mean walking itself is a gimmick. Today’s guest shares why he is so passionate about walking and the research that supports this accessible habit, one that can be incorporated into most people’s lives and lead to significant results and shifts in their health and wellness journey.
Today on The Dhru Purohit Show, Dhru sits down with Greg Mushen to explore the profound benefits of walking as a fundamental aspect of health and wellness. Greg shares how walking can be more effective than medications for managing blood sugar. He explains why maintaining a high step count supports weight loss and mood regulation, and highlights the critical role walking plays in cardiovascular health. He also emphasizes the importance of fiber and potassium in the diet, the influence of genetics on health, and the benefits of personal experimentation in achieving optimal outcomes. The conversation reveals why walking, one of the most low-cost and accessible habits, could be the missing link to better health and why you’ll want to hear the data for yourself.
Greg Mushen is a health researcher, writer, and systems thinker with a long career in the tech industry. After years of building and scaling technology products, he turned his focus to one of medicine’s biggest puzzles: why subsistence populations largely avoid chronic disease. His approach combines anthropology with modern science, connecting lipid kinetics, gut microbiome ecology, and evolutionary biology into a systems-level understanding of human health. A lifelong builder, whether in startups, overland rigs, or new health frameworks, Greg now approaches human healthspan as the ultimate engineering problem: resilience, adaptability, and longevity.
In this episode, Dhru and Greg dive into:
The importance of doubling down on walking (1:10)
Greg’s physical transformation through walking (9:31)
Combining walking with resistance training (20:26)
The link between lipid clearance, fat oxidation, and walking (26:25)
Incorporating regular movement into daily life (27:45)
Key comparisons between walking and running (34:08)
Developing an elite VO₂ max (37:47)
Vascular stiffening and endoPAT testing (41:47)
Why fiber intake matters and how Greg increases intake (44:45)
The role of genetics in cardiovascular health (58:43)
The importance of potassium in the diet (1:08:15)
Lessons from subsistence populations on chronic disease (1:14:02)
Final thoughts and key takeaways (1:15:12)
Also mentioned in this episode:
Study on the Association of Daily Step Count and Step Intensity With Mortality Among US Adults
Study on Postmeal Exercise Blunts Postprandial Glucose Excursions In People On Metformin Monotherapy
Try This: 5 Things I Changed After Getting Genetic Testing
Greg’s Chili Recipe
For more on Greg, follow him on X/Twitter, Instagram, Threads, and Substack.
This episode is brought to you by BiOptimizers, Cozy Earth, and Fatty15.
Go to bioptimizers.com/dhru now and enter promo code DHRU to get 30% off any order of Magenesium Breakthrough and find out this month’s gift with purchase.
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This episode is brought to you by Bon Charge and AquaTru.
Dwindling memory is often seen as a normal part of aging. But just because it’s common doesn’t mean it’s normal. There’s a lot we can do to safeguard the memory center of our brain, and it’s never too late to start.
Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Dr. Majid Fotuhi. He unpacks how excess sugar from a highly refined, processed diet can accelerate aging and damage key organs, including the kidneys, liver, and brain. Dr. Fotuhi also highlights animal studies linking sugar to brain decline, the blood markers we should all be monitoring, and practical strategies to support brain growth. Finally, he shares why having a strong sense of purpose is one of the most powerful ways to protect brain health.
Dr. Fotuhi is a neurologist specializing in memory, concussion, and successful aging. With over 30 years of teaching, clinical practice, and neuroscience research at Harvard Medical School and Johns Hopkins, he has developed a multidisciplinary program to help people of all ages improve memory and attention. The results of his program have been published in numerous scientific journals as well as in his three books. Passionate about public education on brain health, Dr. Fotuhi also teaches in the Department of Psychological and Brain Sciences at George Washington University and at Harvard Medical School.
In this episode, Dhru and Dr. Fotuhi dive into:
Why sugar is so damaging to the brain (01:46)
How elevated uric acid levels accelerate brain aging (11:22)
Essential blood markers to monitor regularly (17:27)
Key strategies to support brain growth (21:24)
Why having a sense of purpose is vital for brain health (22:42)
Final thoughts (30:35)
Also mentioned:
Full episode with Dr. Majid Fotuhi
Try This: How Fructose Damages the Brain and Increases Our Risk for Alzheimer’s
This episode is brought to you by Bon Charge and AquaTru.
Right now, Bon Charge is offering my community 15% off. Just go to boncharge.com/DHRU and use code DHRU to save 15%.
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This episode is brought to you by Vuori, Bon Charge, Cozy Earth, and Ollie.
When it comes to fitness, we don’t often think about training our brains. But today’s guest shows us that mental fitness is just as necessary. By rewiring our brains through repeated lessons, we can unlock our full potential and push past limitations.
Today on The Dhru Purohit Show, Dhru sits down with Maya Raichoora to explore the power of the mind, our untapped capabilities, and how to rewire the brain to change the way we think, perform, and believe in what’s possible. Maya explains why what we repeat is often more influential than what is actually real. She also shares how to reframe doubt, practical techniques for visualizing the life we want, and why suppressing emotions can be harmful. Finally, she highlights how we can train our brains to focus on mental fitness and create lasting change.
Maya Raichoora is a leading expert in mental fitness and visualization. She is the founder and CEO of Remap Mental Fitness and an award-winning entrepreneur. Maya has over a decade of experience and has made history as Nike’s first-ever mental fitness trainer. She has mastered the practice of visualization and is on a mission to make it accessible to all. A two-time TEDx speaker, her story and insight continue to inspire and educate audiences around the world.
In this episode, Dhru and Maya dive into:
Our brain doesn’t care what’s real, only what’s repeated (1:00)
What holds people back from rewiring their brains (3:39)
Why we should doubt our limitations instead of our potential (8:25)
First steps to training the mind and building awareness (18:00)
Maya’s personal story that led her to pursue her passion and profession (21:55)
Five key techniques of visualization (33:09)
Why suppressing emotions damages the mind, body, and life (43:53)
How to build mental fitness (48:20)
Habits and behaviors that shape our thinking and well-being (51:52)
Building confidence and self-confidence (57:15)
How to break free from the habit of complaining (58:48)
Routines that helped Maya step into the power of the mind (1:08:13)
How Maya recovered from her illness (1:10:28)
The core message of Visualise (1:17:12)
Red flags to watch for in dating (1:20:58)
Final thoughts and takeaways (1:24:43)
Also mentioned in this episode:
Visualise Book
For more on Maya, follow her on Instagram, Threads, LinkedIn, Apple Podcasts, Spotify, or visit her Website.
This episode is brought to you by Vuori, Bon Charge, Cozy Earth and Ollie.
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In the noisy debate over diets, calories, and weight loss, it can be hard to separate fact from hype. Today’s guest draws on deep expertise to cut through the noise, break down the science, and deliver trustworthy insights into nutrition and wellness.
Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Dr. Layne Norton. Dr. Norton shares why exercise is critical for sustained weight loss and appetite regulation. He also explains that the decision to make lifestyle changes, along with consistency, is key to long-term success. Dr. Norton further discusses how the standard American lifestyle complicates weight loss and why it’s necessary to take an empathetic approach to helping people succeed.
Dr. Layne Norton is a renowned fitness coach, bodybuilder, and entrepreneur known for his evidence-based approach to nutrition and training. He earned a Ph.D. in Nutritional Sciences from the University of Illinois and has achieved significant milestones as a competitive bodybuilder and powerlifter, including winning national titles and setting world records. Dr. Norton is also the founder of BioLayne LLC, a fitness and nutrition coaching company that has helped countless individuals achieve their health and fitness goals. He is also a prolific writer, speaker, and social media influencer, using his platforms to debunk fitness myths and promote science-based practices.
In this episode, Dhru and Dr. Norton dive into:
The importance of exercise for long-term weight loss (1:44)
Exercise and appetite regulation (5:20)
Stories of people who decided to change their lifestyle (16:11)
The standard American lifestyle of convenience (23:41)
Why some people struggle with appetite control and the role of Ozempic (33:02)
Accountability and the need for an empathetic approach to weight loss (38:42)
Final thoughts (42:29)
Also mentioned:
Full episode with Dr. Layne Norton
This episode is brought to you by Maui Nui and Birch Living.
Right now, Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products. Just go to mauinuivenison.com/dhru to secure your access now, but hurry, supply is limited!
Get 25% off your Birch Living mattress during their extended Labor Day sale —just head to birchliving.com/dhru today!
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This episode is brought to you by One Skin and Momentous.
Cardiovascular disease remains the leading cause of death worldwide. But today, we no longer have to wait for symptoms to understand our risk. Advances in technology now make it possible to get a clear snapshot of individual risk, not only for heart disease, but also for cancer and neurodegenerative conditions, empowering us to take proactive steps to lower risk and support long-term health. Our guest today breaks down what’s truly worth investing in and what we can skip.
Today on The Dhru Purohit Show, Dhru sits down with Dr. Eric Topol, a cardiologist and Professor of Molecular Medicine at the Scripps Research Institute. Dr. Topol shares insights on the importance of preventive health, with a focus on cardiovascular disease, cancer, and neurodegenerative conditions. He explains the role of polygenic risk scores in assessing individual risk, explores the strengths and limitations of various testing methods, and highlights how lifestyle choices shape disease prevention. Dhru and Dr. Topol also discuss emerging technologies in health monitoring, the influence of environmental factors like air pollution, and what the future may hold for aging and health management.
Dr. Eric Topol is Executive Vice President and Professor of Molecular Medicine at Scripps Research and founder of the Scripps Research Translational Institute. A practicing cardiologist and one of the ten most-cited researchers in medicine, he is renowned for his wor in AI, genomics, and digital clinical trials. Named to the Time 100 Health list in 2024, he also writes the Ground Truths newsletter and is the author of The Creative Destruction of Medicine, The Patient Will See You Now, Deep Medicine, and Super Agers.
In this episode, Dhru and Dr. Topol dive into:
Cardiovascular disease causes, risks, and prevention (1:07)
Polygenic risk genetic links to disease and understanding your risk (7:56)
Heart health with Dr. Topol’s key recommendations (13:21)
Cancer testing types of tests and how to approach results (27:47)
Medical guidance mistrust, confusion, incidental findings, and the importance of evidence-based practitioners (34:20)
Alzheimer’s detection, blood work, testing, and the role of AI (43:13)
Environmental risks, air pollution, and sleep irregularity, and why these factors must be addressed (53:20)
Parkinson’s disease: the fastest-growing neurodegenerative condition (57:01)
Prevention and lowering your risk of developing major diseases (59:52)
Gut health and the gut-hormone connection (1:02:05)
Aging and immunity: links between age-related diseases and the immune system (1:06:19)
Measuring biological age (1:08:14)
Final thoughts and takeaways (1:16:27)
Also mentioned in this episode:
Super Agers: An Evidence-Based Approach to Longevity
Polygenic Risk Scores: Ready for Prime Time?
What a Polygenic Risk Score Can and Can’t Tell You
Allelica Polygenic Risk Test
Dhru’s APOE Chat GPT Results
For more on Dr. Topol, follow him on X/Twitter, The Scripps’ socials: X/Twitter, Facebook, Instagram, YouTube, TikTok, Threads, LinkedIn, Bluesky, or visit their Website.
This episode is brought to you by One Skin and Momentous.
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This episode is brought to you by Branch Basics and Bon Charge.
What if you could lower your risk of cardiovascular disease by 69%? Today’s guest reveals how regular sauna usage, one of the most underrated tools for longevity, brain health, and cardiovascular function, can make that possible.
Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Dr. Susanna Søberg on the benefits of consistent sauna use. Dr. Søberg highlights the added impact of pairing sauna with exercise, offers practical tips for adapting to the heat, and shares the latest research showing how sauna use can reduce all-cause mortality and boost nitric oxide production.
Dr. Susanna Søberg is one of the world’s leading researchers and experts in cold and heat therapy, as well as functional breathing. She is the founder of the Soeberg Institute, which offers an online, research-backed curriculum designed to help people optimize stress management and performance for a healthier, happier life. Dr. Søberg earned her PhD in metabolism at the University of Copenhagen, where her research advanced our understanding of brown fat metabolism in adults.
In this episode, Dhru and Dr. Søberg dive into:
The health benefits of regular sauna use (1:27)
Pairing sauna with exercise for an extra boost (3:20)
How to adapt to heat in the sauna (8:15)
Research on sauna use and reducing all-cause mortality (12:37)
How the brain responds to sauna (15:34)
Sauna and nitric oxide production (18:29)
Also mentioned:
Full episode with Dr. Susanna Søberg
Try This: 2 Fascinating Studies, Sauna Benefits, a Way to Beat Jet Lag, and More
Try This: Sauna Bathing for Longevity, Cognition, & Heart Health
This episode is brought to you by Branch Basics and Bon Charge.
Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use the coupon code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics!
Right now, Bon Charge is offering my community 15% off; just go to boncharge.com/DHRU and use the coupon code DHRU to save 15%.
Sign up for Dhru’s Try This Newsletter
Learn more about your ad choices. Visit megaphone.fm/adchoices
This episode is brought to you by BiOptimizers, Birch Living, and Our Place.
Autism rates have increased fivefold over the past twenty years. While much remains unknown about how children develop autism, research suggests that the rise in cases may not be explained by increased diagnoses alone. Today’s guest takes us on a deep dive into autism and shares his proposals for reducing these rates.
Today on The Dhru Purohit Show, Dhru sits down with Dr. Jeff Zadeh for a deep dive into autism and the research he’s uncovered on key strategies that may reduce the likelihood of a child being diagnosed with autism. While Dr. Jeff acknowledges that much remains unknown about why some children are on the autism spectrum, he highlights the top nutrients and vitamins women should focus on before pregnancy to help lower the risk. From dosages to deficiencies, Dr. Jeff breaks down what the research shows so far. He also shares his personal journey with his son’s diagnosis and what inspired him to begin exploring this topic in depth.
Dr. Jeff Zadeh, a board-certified internist with nearly 30 years of experience, founded Dallas Medical Specialists in 2005 and later moved his practice to rural North Texas, where he serves as a hospitalist, trauma director, and emergency physician. After his oldest son was diagnosed with autism, he discovered research suggesting many cases may be preventable through prenatal counseling, yet most physicians were unaware of it. Inspired by this and the work of Dr. David Berger, he wrote Autism Prevention 5 Days a Week to share simple, evidence-based prevention strategies in accessible language.
In this episode, Dhru and Dr. Zadeh dive into:
Dr. Zadeh’s personal journey with his son’s autism diagnosis (00:55)
Dr. Zadeh’s medical background and the challenges of obtaining a diagnosis (8:50)
The importance of supplementation before conception (27:32)
What to look for in prenatal vitamins (45:27)
The 5-day-a-week proposal and the studies behind it (49:55)
Maintaining sufficient iron levels in women (1:06:33)
Why checking thyroid levels before pregnancy is essential (1:15:21)
Environmental toxin exposures affecting pregnancy (1:15:26)
The risks of taking Tylenol during pregnancy (1:27:23)
The connection between celiac disease and autism (1:31:35)
How increasing DHA omega-3 and vitamin D intake may lower the risk of autism (1:35:32)
The role of choline in autism prevention (1:51:12)
Key factors we should pay attention to (1:54:47)
Dr. Zadeh’s reflections as a parent of a child on the autism spectrum (2:00:20)
Final thoughts and takeaways (2:07:30)
Also mentioned in this episode:
Dr. Jeff Zadeh’s Slides
Autism Prevention 5 Days a Week
Dr. Rhonda Patrick BPA Instagram Post
For more on Dr. Zadeh, follow him on X/Twitter and visit his Website.
This episode is brought to you by BiOptimizers, Birch Living, and Our Place.
Upgrade your digestion with enzymes! Go to bioptimizers.com/dhru now and enter promo code DHRU to get 15% off any order and free gifts for a limited time.
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This episode is brought to you by Pique Life and Branch Basics.
Air quality and mold are major factors in overall health and wellness. In fact, 70% of homes in the United States contain at least one species of mold. Exposure can trigger chronic inflammation, fatigue, and brain fog, but with the right knowledge, you can take proactive steps to protect your health.
Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Michael Rubino to explore how and why mold is so prevalent in most homes and how it can worsen autoimmune disease. Michael breaks down the most common sources of mold people encounter and why the problem is getting worse. He also highlights the four most toxic types of mold and explains how their presence in the body can cause damage through self-preservation mechanisms. Finally, Michael explains why some people are more susceptible to the effects of mold than others.
Michael Rubino is the Founder of HomeCleanse, President of the Change the Air Foundation, and host of the Never Been Sicker podcast. A council-certified Mold Remediator with a background in construction, he focuses on helping immunocompromised individuals recover from mold exposure.
In this episode, Dhru and Michael dive into:
Why mold is the number one toxin found in homes (1:56)
The most common sources of mold people encounter (6:11)
Why the mold problem is getting worse (7:28)
Memorable client stories (13:22)
Types of mold to watch out for (18:32)
The four most toxic molds (20:08)
How mold damages the body through self-preservation mechanisms (24:01)
Why some people are more affected by mold than others (26:08)
Final thoughts (28:03)
Also mentioned:
Full episode with Michael Rubino
This episode is brought to you by Pique Life and Branch Basics.
Right now, Pique Life is offering 20% off their Sun Goddess Matcha. Plus, you’ll get a free beaker and frother when you go to piquelife.com/dhru.
Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics!
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This episode is brought to you by Cozy Earth, LMNT, and Fatty15.
Have you ever had a sign or a gut feeling that you brushed off as a coincidence? What if those moments weren’t random at all, but subtle guidance pointing you in the right direction? On today’s episode, we explore how these signs show up in our lives, why we often miss them, and how understanding the science behind intuition can help us tune in and act with clarity.
Today on The Dhru Purohit Show, Dhru sits down with world-renowned neuroscientist Dr. Tara Swart to explore the key signs of greater intelligence that often appear in our lives. She explains how our modern world can prevent us from noticing these signs and receiving guidance, and how the brain itself acts as a filter. Through practices such as visualization and intention-setting, we can activate the reticular activating system to better recognize opportunities that align with our goals. Dr. Tara also breaks down the science of intuition and “signs,” showing how gut feelings and dreams are rooted in real brain-body connections, while offering practical tools to rewire limiting beliefs. She reminds us that transformation isn’t magic, but rather biology combined with aligned action.
Dr. Tara Swart is a PhD neuroscientist and Oxford University-trained medical doctor. She is Senior Advisor for Neuroscience and Leadership at MIT Sloan School of Management, best-selling author of The Source, and a Trustee of the Lady Garden Foundation. Tara is the Chief Science Officer at Dirtea, an adaptogenic mushroom company, and the Mind Ambassador at Healf.com. Tara is passionate about empowering people through the intersection of science and spirituality.
In this episode, Dhru and Dr. Swart dive into:
Dr. Tara’s personal story of loss, grief, and her journey with signs and patterns (1:10)
Fundamental beliefs we accept without proof and a discussion on near-death experiences (7:02)
What Dr. Tara realized after her husband’s death and the greater source present in the universe (17:24)
The importance of having community (20:17)
Dhru’s personal story of signs after loss (21:25)
How Dr. Tara navigated her grief and what led her to write her book (38:50)
Why sharing your experiences with signs matters and how to identify your own (47:14)
Finding a sense of purpose through signs (1:07:00)
Practices to help us access and strengthen our intuition (1:18:57)
The power of journaling (1:23:21)
What to do when you ask for a sign and don’t get one (1:29:56)
Feeling connected to signs while staying grounded in real life (1:34:35)
The consequences of ignoring the signs life gives us (1:41:45)
Final thoughts and takeaways (1:45:55)
Also mentioned in this episode:
The Signs: The New Science of How to Trust Your Instincts - Dr. Tara’s new book
For more on Dr. Swart, follow her on Facebook, X/Twitter, Instagram, LinkedIn, or visit her Website.
This episode is brought to you by Cozy Earth, LMNT, and Fatty15.
Right now, get 40% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP.
Lemonade Salt flavor is here to stay! Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to drinkLMNT.com/dhru today.
Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health.
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This episode is brought to you by Maui Nui and AquaTru.
We’ve heard from many experts about why reducing alcohol use can be highly beneficial to health, and it seems people are starting to take notice. More young adults today are cutting back on their drinking. But for many, reducing alcohol isn’t always easy. Today’s guest unpacks how alcohol became such a central part of our social lives and shares strategies for moving toward cutting down.
Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about conversations with Ruari Fairbairns on the key role alcohol plays in our social lives. Ruari explains why it’s so difficult to change our relationship with alcohol and how, for some, cutting back can actually lead to feelings of disconnection. He also opens up about his own journey with alcohol, how his relationship with it has evolved over the years, and what alcohol use can reveal as a deeper signal in our lives.
Ruari Fairbairns is the founder and CEO of OYNB (One Year No Beer) and a leading figure in the health and well-being space. He was awarded Great British Entrepreneur of the Year for Scotland and Northern Ireland 2020, and OYNB was also named The Spectator’s Economic Innovator of the Year in the UK. Known for his passionate advocacy for healthier living, Ruari has inspired over 100,000 people worldwide to reassess their relationship with alcohol and strive to become the best version of themselves.
In this episode, Dhru and Ruari dive into:
The need for connection and joining the tribe as a hindrance to stopping alcohol (1:33)
Ruari’s relationship to alcohol (8:16)
Reasons people choose to numb out with alcohol (18:15)
The role of the ego in alcohol use (19:40)
Regulating your nervous system and stress relief (22:50)
Final Thoughts (24:48)
Also mentioned:
Full episode with Ruari Fairbairns
This episode is brought to you by Maui Nui and AquaTru.
Right now, Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products. Just go to mauinuivenison.com/dhru to secure your access now, but hurry, supply is limited!
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This episode is brought to you by Cozy Earth, Branch Basics, and Bon Charge.
Despite what most people think, aging does not have to mean decline. With the right mindset, proper nutrition, and consistent movement, you can take control of your health, build resilience, and stay strong, balanced, and unbreakable well into the later decades of life. Today’s guest shows us how.
Today on The Dhru Purohit Show, Dhru sits down with Dr. Vonda Wright to unpack the misconceptions surrounding aging, especially the belief that aging automatically means decline. She emphasizes the importance of mindset, hormone optimization, and lifestyle adjustments in enabling women to approach aging with strength and positivity. They explore the critical role of nutrition, physical activity, and mental resilience in maintaining health and vitality through midlife. Dr. Wright also introduces her FACE protocol, a framework designed to promote long-term physical resilience. If you’re looking for inspiration to prioritize your health, stay strong, and become unbreakable as you age, this episode is for you.
Dr. Vonda Wright is a double-board-certified orthopedic surgeon, researcher, and expert in active aging and mobility. With over 20 years of experience, she specializes in helping athletes and active individuals maintain strength, mobility, and injury-free status at every stage of life. Dr. Wright combines cutting-edge technology with minimally invasive techniques and a patient-first approach to deliver personalized, high-performance care. Beyond the operating room, she’s a passionate advocate for helping people lead vibrant, active lives well into their later years.
In this episode, Dhru and Dr. Wright dive into:
Why believing that aging means decline is destructive to our health (00:30)
How Dr. Wright helps women change their perspective about aging (3:15)
Core beliefs women hold about aging (5:10)
Dr. Wright's personal story and the steps she took to embrace aging (8:07)
What are these aging "ticking time bombs"? (18:18)
The effects of estrogen during perimenopause and menopause (21:12)
Changes to our bones during aging and the causes of bone deterioration (23:45)
Best practices to get the hormonal help women need (36:15)
The FACE framework: flexibility and joint mobility, aerobic, carry a load, equilibrium, and foot speed (42:07)
How strategically stressing our bodies improves health (45:24)
How to improve your VO2 max and Dr. Wright’s resistance training protocol (49:42)
The top nutrition tips and supplements for bone health (1:09:42)
Committing to resilience (1:24:42)
Final thoughts (1:26:10)
Also mentioned in this episode:
Unbreakable: A Woman's Guide to Aging with Power
Alloy Health
Midi Health
For more on Dr. Wright, follow her on Facebook, X/Twitter, Instagram, YouTube, LinkedIn, or visit her Website.
This episode is brought to you by Cozy Earth, Branch Basics, and Bon Charge.
Right now, get 40% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP.
Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics!
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This episode is brought to you by Maui Nui and Birch Living.
What if a single nutrient could protect your brain, fight inflammation, and add healthy years to your life? Omega-3 can do all that and yet, over 95% of people are running on empty.
Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Dr. Bill Harris. He shares groundbreaking research linking high omega-3 levels to Alzheimer’s and dementia prevention, and how omega-3s can help reduce overall chronic inflammation. Dr. Harris also reveals what’s considered optimal for omega-3 levels, the shocking range most Americans fall into, and how this widespread deficiency is closely tied to the overconsumption of ultra-processed foods.
William S. Harris, PhD, FASN, has been a leading researcher in the omega-3 fatty acid field for 40 years. He has authored over 300 scientific papers on fatty acids and health, has been on the faculty of three medical schools, and has received five NIH grants to study omega-3. He co-authored three AHA statements on fatty acids and heart health. As the co-inventor of the Omega-3 Index (and other omega-3 blood tests) and founder of OmegaQuant Analytics, Dr. Harris has been ranked among the top 2% of scientists worldwide based on the impact of his research.
In this episode, Dhru and Dr. Harris dive into:
High omega-3 levels and their correlation with reduced risk of dementia and Alzheimer’s (1:50)
Research on omega-3s and their role in reducing chronic inflammation (6:22)
Average omega-3 levels vs. optimal levels (12:19)
Causes of omega-3 deficiencies and the rise of ultra-processed food consumption (14:41)
How fish oil can lower triglyceride levels and impact cellular health (12:25)
Final thoughts (20:15)
Also mentioned:
Full episode with Dr. Bill Harris
This episode is brought to you by Maui Nui and Birch Living.
Right now, Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products. Just go to mauinuivenison.com/dhru to secure your access now but hurry, supply is limited!
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This episode is brought to you by Vuori, One Skin, Momentous, and LMNT.
Fiber is one of the most overlooked nutrients in the modern diet, and most of us aren’t getting enough. Lower fiber intake is linked to increased risks of chronic disease, digestive problems, and poor metabolic health, but boosting your intake can be simple and enjoyable. Today’s guest shares the unique benefits of different types of fiber and how gradually increasing intake can support gut health, cholesterol levels, liver function, and other health benefits.
Today on The Dhru Purohit Show, Dhru sits down with Dr. Karan Rajan to unpack the critical role of fiber in our diets and why most of us aren’t getting nearly enough. He shares his personal health journey and how increasing his fiber intake transformed his well-being. Dr. Karan discusses the different types of fiber, their science-backed benefits, and simple, practical ways to work more high-fiber foods into your day. He also explains the hidden dangers of fiber deficiency, its link to chronic diseases like colon cancer, and the surprising potential of fiber to help flush out microplastics from the body.
Dr. Karan Rajan is a doctor and one of the biggest health & science creators on social media. Since 2020, he has amassed over 11 million followers across TikTok, YouTube, Instagram & Facebook with his refreshingly frank medical myth-busting and health advice videos which combine education, entertainment, and generous servings of dark humour.
In this episode, Dhru and Dr. Rajan dive into:
The fiber deficiency crisis (00:10)
Understanding fiber's role in gut health (1:29)
Types of fiber and how to increase our intake (05:55)
The evolution of dietary choices (13:23)
Navigating fiber sensitivities (17:20)
Essential high-fiber foods (25:42)
The consequences of low fiber intake (33:10)
Fiber and colon cancer risk (37:23)
Understanding the role of fiber in removing microplastics (40:06)
Fiber's impact on cholesterol and heart health (45:47)
Optimizing liver health (50:53)
Rethinking the 10,000 steps myth (53:40)
Patterns over perfection in health (59:05)
The importance of sleep in health (1:00:42)
Smart supplementation strategies (1:05:01)
Final thoughts and takeaways (1:09:09)
Also mentioned in this episode:
Dr. Karan’s Blog Post on Pantry Staples
For more on Dr. Rajan, follow him on Facebook, X/Twitter, Instagram, YouTube, TikTok, LinkedIn, or visit his Website.
This episode is brought to you by Vuori, One Skin, Momentous, and LMNT.
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This episode is brought to you by Branch Basics and AquaTru.
Losing weight is often easier than keeping it off. Crash diets and trendy programs might help you drop pounds quickly, but experts know those clickbait tips don’t last. Today’s guest shares the key traits of people who successfully reach and maintain their weight loss goals.
Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with certified personal trainer, nutritionist, and bodybuilding coach Dr. Allan Bacon. Dr. Bacon breaks down the three common traits shared by people who lose weight and keep it off long term and why they work. He also explains how to shift from a restrictive approach to a goal-setting mindset, and how our ability to lose weight changes as we age.
Dr. Allan Bacon, who holds a Doctorate in Dental Surgery from the University of Maryland. He is a certified personal trainer through the National Academy of Sports Medicine, a certified nutritionist and physique/bodybuilding coach, a USA Powerlifting coach, and has over 15 years of experience formulating for leading dietary supplement companies. His work has been featured in Muscle & Fitness, Sci-Fit, the Alan Aragon Research Review, and The Personal Trainer Development Center. Dr. Bacon specializes in helping working adults master their physique, performance, mindset, and habits to achieve sustainable, lifelong results.
In this episode, Dhru and Dr. Bacon dive into:
Best and worst ways to lose 10 lbs (1:29)
Three common characteristics of lifelong, sustained weight loss (2:07)
Optimal mindset for maintaining weight loss(11:15)
Why weight loss becomes more challenging as we age (17:41)
Final thoughts (24:31)
Also mentioned:
Full episode with Dr. Allan Bacon
This episode is brought to you by Branch Basics and Air Doctor.
Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use the coupon code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics!
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This episode is brought to you by Fatty15, Levels, and Ollie.
When it comes to diet mistakes and fad diets, social media is full of trends and extreme ideas. But what works, stands the test of time, and is sustainable in the long run? Today’s guest shares his experience and top tips without leaving you feeling deprived.
Today on The Dhru Purohit Show, Dhru sits down with celebrity trainer and evidence-based educator Harley Pasternak to discuss the biggest diet mistakes he’s seen with his clients. Harley shares his controversial take on cutting out entire food groups and following overly restrictive diets. He also breaks down the top reasons why people overeat, introduces his PATH protocol, and explains the success his clients have experienced using it. Plus, Harley reflects on how his views have evolved over the years and highlights the research that now supports his current beliefs on sustainable weight loss and healthy living.
Harley Pasternak is the author of six popular diet and fitness books, including the New York Times bestsellers The Body Reset Diet and The 5-Factor Diet. He holds a Master of Science degree in exercise physiology and nutritional sciences from the University of Toronto and an honors degree in kinesiology from the University of Western Ontario. He is an adjunct professor at the Dalla Lana School of Public Health at the University of Toronto. Harley Pasternak lives with his wife and two children in Los Angeles.
In this episode, Dhru and Harley dive into:
Breaking down the biggest diet mistakes (00:24)
Why removing carbs from our diet is detrimental to our health (2:31)
The PATH protocol (20:35)
Excess fat consumption and how to balance calories in and out (25:05)
Why are we overeating? (37:41)
Harley's carb hierarchy (47:36)
Things Harley changed his mind on (56:15)
Harley’s perspective on health: the art of moderation (1:05:59)
Toxin exposure, social media, and living an active lifestyle (1:09:09)
Final thoughts and takeaways (1:14:18)
Also mentioned in this episode:
THE CARB RESET: Store Less Fat, Burn the Rest, and Harness the Power of Carbs to Lose Weight
For more on Harley, follow him on Instagram, TikTok, LinkedIn, or visit his Website.
This episode is brought to you by Fatty15, Ollie, and Levels.
Fatty15 is offering an additional 15% off its 90-day subscription Starter Kit. Go to fatty15.com/dhru and use code DHRU to replenish your C15 levels for long-term health.
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This episode is brought to you by Pique Life and Bon Charge.
We know that exercise and diet play a major role in longevity, but social interactions and meaningful connections also have a powerful impact on how we age. In this episode, you’ll learn how to foster relationships that energize you—not drain you—and avoid the trap of unwanted interactions and energy vampires. If you’re looking to live a happier, longer life, this episode shows you how.
Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with behavioral researcher Vanessa Van Edwards. Vanessa explores how key personality traits, like charisma, can contribute to a longer, more fulfilling life and help you manifest the life you desire. She breaks down the OCEAN personality model and discusses which traits may support or hinder longevity. Vanessa also shares examples of social interactions that drain your energy and offers practical tools to help you navigate conversations with greater ease and confidence.
Vanessa Van Edwards is a multi-time bestselling author and a renowned behavioral researcher specializing in professional communication and leadership. Vanessa’s work has been featured in national and international media, as well as in workshops worldwide.
In this episode, Dhru and Vanessa dive into:
How charisma can help you live longer and get what you want (1:16)
Key personality traits you can develop to support longevity (2:17)
How to conserve energy and manage your social battery (10:05)
Why life gets easier when you step into your charisma (12:05)
Practical tools to feel more at ease in social interactions (22:56)
Final thoughts (24:52)
Also mentioned:
Full episode with Vanessa Van Edwards
This episode is brought to you by Pique Life and Bon Charge.
Right now, Pique Life is offering 20% off their Sun Goddess Matcha. Plus, you’ll get a free beaker and frother when you go to piquelife.com/dhru.
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This episode is brought to you by BiOptimizers, Birch Living, and Cozy Earth.
Research on brain health is continually evolving. However, what we know for sure is that doubling down on the basics, including daily habits and key supplements, can go a long way in protecting our brains as we age. It’s never too early or too late to start. Today’s guest breaks down what’s truly worth prioritizing for long-term brain health.
Today on The Dhru Purohit Show, Dhru sits down with neurophysiologist Louisa Nicola to explore the latest science on brain health, Alzheimer’s disease, and the impact of creatine. Louisa breaks down current research on optimal creatine dosing and highlights the critical roles that omega-3s and vitamin D play in brain health and cognition. She also shares tips for choosing high-quality supplements, the top sources of inflammation in our modern lifestyle, and the protective power of exercise, including what’s known as bone-brain crosstalk. If you’re looking for science-backed strategies to protect your brain and prevent cognitive decline, this episode is a must-listen.
Louisa Nicola is a neurophysiologist and sports scientist specializing in brain performance and human potential. She founded Neuro Athletics in 2016 to help athletes, executives, and high performers optimize brain health. With a background in neuroscience and sports science, her work focuses on cognitive training, neuroplasticity, and mental resilience.
In this episode, Dhru and Louisa dive into:
The latest research on creatine and its role in reducing Alzheimer’s risk (00:46)
Working memory, neuroplasticity, and cognitive function (8:10)
Why creatine matters and the benefits it offers (18:44)
How to take creatine and avoid fake supplements online (22:29)
The importance of maintaining optimal vitamin D levels (28:27)
Why omega-3s are essential for preventing cognitive decline (39:59)
Top sources of inflammation in modern life (50:14)
Why improving air quality is critical for brain health (54:24)
How exercise helps boost and maintain nitric oxide levels (1:00:01)
The surprising link between leg strength and brain function and how to build it (1:11:09)
What we know about bone-brain crosstalk (1:17:04)
How red light therapy supports collagen and healthy aging (1:27:48)
Why Dr. Louisa changed her mind about ice baths (1:30:41)
The powerful role of high-quality relationships and community in brain health (1:33:29)
Final thoughts and takeaways (1:36:39)
Also mentioned in this episode:
Substack
Supp.co
Reverse 20 Years of Aging-Ben Levine Study
ATMO air monitor
For more on Louisa, follow her on X/Twitter, Instagram, Neuro Athletes' Instagram, Facebook, YouTube, Apple Podcasts, LinkedIn, or visit her Website.
This episode is brought to you by BiOptimizers, Birch Living, and Cozy Earth.
Go to bioptimizers.com/dhru now and enter promo code DHRU to get 15% off any order of Magenesium Breakthrough and find out this month’s gift with purchase.
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This episode is brought to you by Momentous and AquaTru.
According to today’s guest, the roots of Alzheimer’s are planted decades before symptoms appear. That means it’s never too early to take action. Today’s guest, Dr. David Perlmutter, shares powerful lifestyle strategies to protect your brain and lower your risk of neurodegenerative disease.
Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Dr. David Perlmutter to discuss research on the top four factors that can determine the risk of developing Alzheimer’s and his lifestyle tips for prevention. Dr. Perlmutter shares the tools we can use to analyze our brain’s energy use and discusses the importance of engaging in physically and mentally stimulating activities.
Dr. David Perlmutter is a Board-Certified Neurologist and five-time New York Times bestselling author. He serves on the Board of Directors and is a Fellow of the American College of Nutrition. He is the author of Grain Brain and Drop Acid. He serves as a member of the Editorial Board for the Journal of Alzheimer’s Disease. He has published extensively in peer-reviewed scientific journals, including Archives of Neurology, Neurosurgery, and The Journal of Applied Nutrition.
In this episode, Dhru and Dr. Perlmutter dive into:
How belly measurements can reveal metabolic health (01:21)
Four key factors that determine Alzheimer’s risk (6:00)
The impact of refined carbs vs. colorful foods on brain health (8:10)
How blood pressure and nitric oxide affect cognitive function (11:08)
The surprising connection between the oral microbiome and brain health (19:54)
Tools to assess how efficiently the brain uses energy (22:54)
How a sedentary lifestyle increases the risk of cognitive decline (25:12)
Final thoughts and takeaways (27:34)
Also mentioned:
Full episode with Dr. David Perlmutter
This episode is brought to you by Momentous and AquaTru Shower.
Support your energy, bones, and resilience with The Women’s Three: Iron, Calcium, and Vitamin D3—formulated by experts, made for women. Head to livemomentous.com and use code DHRU for 35% off your first subscription.
Right now, AquaTru is offering my community $50 off their new shower filter. Ready to upgrade your shower? Visit dhrupurohit.com/shower to experience the AquaTru Shower difference.
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could you please put the name of the person you talk with at the title of episode? Or her/his picture on the episodes picture? It would be a great help to finde the desierd episode.
This episode must have been the best one I've heard on Narcissism. Thank you!
Have to love Gabor!
great episode. thank you
I just ordered this book. Stuart makes sense!
This is a great podcast, it provides practical, actionable advice based on scientific research. I appreciate the guest selection: Dhru hosts a variety of esteemed guests, including leading researchers and practitioners. This variety adds depth and multiple perspectives to the discussions!
I heard found Dhru through a random search on health, and he made a lot of sense- I have been a regular listener for several years- he has great guests asks probing questions and I have found several others to learn from in this category- Thank you Dhru!
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this was interesting, although he stigmatizes drug users with comments like "ew, drug user brain". the free will comments were helpful as well.
Best podcast on cold water therapy yet!
I listen to your podcast while I’m preparing meals for my work week and just wanted to let you know how inspiring this podcast and how good it makes me feel about the food I’m making. It makes being questioned by my fast food eating coworkers about what I’m eating worth it.
Such an excellent episode. Many important tools that anyone can learn.
How in the world can you say that sugar and insulin spike and that's not a problem?
Loved it. I listen to all you podcast, look forward to them and pass themon to close friendsat work.. Cheers.
A much needed peptalk to scare away the winterblues
Love the breath knowledge from James Nestor
love this, thank you!
I love that it gets straight to the point
Miu m
soooooo good! thank you for introducing me to this artist! I will buy his book. Such deep and important conversations!!