What if everything you've been told about longevity supplements is based on hype rather than science? Dr. Eric Verdin, CEO of the Buck Institute for Research on Aging, joins me on the Extend podcast to separate fact from fiction in the longevity field. We explore epigenetic reprogramming, why the immune system controls aging, and the reality that no supplements are proven to extend human lifespan. We also discuss how most people could live to 95 in good health using lifestyle interventions we already know work. Dr. Eric Verdin is the CEO and President of the Buck Institute for Research on Aging, the world's first independent research institute focused solely on aging. He has published over 200 peer-reviewed papers and is internationally recognized for his research on immune system aging and epigenetic regulation. We Also Discuss: Why There Are No Proven Anti-Aging Supplements or Drugs for Humans Yet How Yamanaka Factors Can Reverse Aging by Reprogramming Cells Back to Youth The Discovery That Immune System Aging Controls Whole-Body Aging Why Your Blood Contains 600 Different Cell Types (Not the 12 You Learned About) How Lifestyle Factors Could Add 30 Years of Healthy Life for Most People The Problem With "Instagram Medicine" and Unproven NAD Infusions Why Brian Johnson's Self-Experimentation Matters Despite the Controversy The Coming Revolution in Precision Medicine and Digital Twins How Organ-Specific Aging Clocks Predict Your Individual Disease Risk Why the Brain and Immune System Are the Two Most Important Aging Targets Thank You for Our Sponsors: Try IM8 today with a 30-day money back guarantee. You can get 10% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Eric Verdin: Instagram: https://www.instagram.com/ericverdin.buck/?hl=en Website: https://www.buckinstitute.org/
What if the blood tests you're not getting are more important than the ones you are? In this episode of Extend, Dr. Jeremy London joins me to explore the three lifestyle modifications that prevent most cardiac disease. We dive into how a continuous glucose monitor revealed his own pre-diabetes despite feeling perfectly healthy. We also share the blood tests your doctor isn't ordering, why vaping may be more dangerous than cigarettes, and how functional medicine filled the gap that traditional surgery couldn't address. Dr. Jeremy London is a board-certified cardiovascular surgeon with over 25 years of clinical experience. He received his medical degree from the Medical College of Georgia and completed his general surgery residency at St. Joseph's Hospital in Denver, Colorado, followed by a vascular and thoracic surgical fellowship at Carolinas Medical Center. Dr. London's mission is to provide accessible health information through his newsletter, podcast, and social platforms. We Also Discuss: Why Vaping Is More Dangerous Than Cigarettes According to This Heart Surgeon The Three Blood Tests Your Doctor Isn't Ordering How a Continuous Glucose Monitor Revealed Pre-Diabetes in a "Healthy" Surgeon Why 50% of Americans Have High Blood Pressure and Most Don't Know It The Calcium Score CT Scan That Reveals Hidden Heart Disease Risk Why VO2 Max Is the Most Powerful Predictor of Longevity How Functional Medicine Saved This Surgeon from Career Burnout The Walking Desk Hack That Gets 10,000 Steps During Work Hours Thank You for Our Sponsors: Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ Timeline: Claim 10% off your first order now at https://www.timeline.com/partners/darshan-shah Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Jeremy London: Instagram: https://www.instagram.com/drjeremylondon / Website: https://www.drjeremylondon.com/
After spending years at a monastery, meditation expert Scott Schwenk discovered the way most people approach meditation is exactly what keeps them from succeeding. The myths around emptying your mind, sitting in painful positions, and chasing mystical experiences sabotage practice before it begins. In this episode of Extend, Scott and I discuss the 4-lens framework that transforms meditation from mystical pursuit to practical life skill. We explore his signature 6-point body softening technique that works in 30 seconds, why he stopped teaching fire breathing after becoming trauma-informed, and how to build a sustainable practice that integrates into real-world challenges. Scott Schwenk is a meditation teacher, breathwork facilitator, and consciousness coach who has spent decades studying both Eastern spiritual traditions and Western psychological approaches. He lived at a monastery, teaches internationally, and helps individuals and businesses integrate contemplative practices into daily life. We Also Discuss: Why "No Thoughts" is Meditation Mythology That Sabotages Your Practice The 6-Point Body Softening Technique That Works in 30 Seconds Why Your Hips Must Be Higher Than Your Knees for Proper Meditation Posture The Secret Taoist Water Meditation Scott Discovered by Accident Nadi Shodhana: The Daily Breathwork Practice That Changes Everything Why Scott Stopped Teaching Fire Breathing After Becoming Trauma-Informed How Mirror Neurons Transfer Meditative States Between People The 4 Lenses Framework: Waking Up, Growing Up, Cleaning Up, Showing Up Why Gurus Fall: Advanced States vs. Psychological Development Open-Eyed Meditation and Why Peak States Can Become Addictive The 3 Questions That Build Meditation Confidence in 30 Days Why You Should Stop While the Practice Still Feels Good Thank You for Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Function Health: The first 1000 get a $100 credit toward their membership. Visit www.functionhealth.com/drshah or use gift code DRSHAH100 at sign-up to own your health. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Scott Schwenk: Instagram: https://www.instagram.com/thescottschwenk/ Website: https://www.scottschwenk.com/
Most people think thyroid issues are just about taking a pill, but over 90% of hypothyroid cases are actually Hashimoto's—an autoimmune condition attacking your thyroid gland. In this episode of Extend, I’m joined by Dr. Izabella Wentz to dive deep into why standard TSH tests fail for years, how artificial sweeteners trigger thyroid dysfunction, and the gut infections that could be destroying your thyroid. We also discuss the lifestyle interventions that can reverse Hashimoto's, the thyroid antibody tests your doctor isn't running, and why an Epsom salt bath might be more powerful than you think. Dr. Izabella Wentz, PharmD, is a clinical pharmacist who has dedicated her career to addressing the root causes of autoimmune thyroid disease after being diagnosed with Hashimoto's thyroiditis in 2009. She's the author of three books and founder of ThyroidPharmacist.com. We Also Discuss: Why Standard TSH Tests Miss Thyroid Disease for 5-10 Years The Complete Thyroid Panel Every Person Should Demand: TSH, T3, T4, Reverse T3, TPO, TG Antibodies How Artificial Sweeteners Trigger Autoimmune Thyroid Disease The Gluten-Thyroid Connection That Can Reverse Hashimoto's Gut Infections Behind Thyroid Dysfunction: H. Pylori, SIBO, and Blastocystis Hominis Why Thyroid Antibodies Attack Your Brain, Fertility, and Mental Health—Even Without Thyroid Hormone Problems The Selenium + Myo-Inositol Protocol That Reverses Early Hashimoto's Why Iron Deficiency Makes Thyroid Medication Useless Synthroid vs. Armour vs. T3: Which Thyroid Medication Actually Works The Hashimoto's Personality: Stress, Trauma, and Autoimmune Disease Red Light Therapy and Cold Laser for Thyroid Regeneration Why Your Thyroid Symptoms Might Actually Be Low Cortisol Thank You for Our Sponsors: Pendulum: Use code DARSHAN or use the link https://pendulumlife.com/discount/DARSHAN to get 20% off Pendulum membership first orders. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Izabella Wentz Instagram: https://www.instagram.com/izabellawentzpharmd/ Website: www.thyroidpharmacist.com
What if the most basic safety research on childhood vaccines has never actually been done? In this episode of Extend, I sit down with Dr. Joel "Gator" Warsh, an integrative pediatrician who's asking the questions about vaccine safety that medicine has avoided for decades. We explore why vaccines are studied against other vaccines instead of true placebos, the shocking absence of vaccinated vs. unvaccinated research, and how financial incentives shape medical recommendations. Dr. Warsh also breaks down his approach to informed consent with parents. This isn't anti-vaccine rhetoric—it's a call for better science. Dr. Joel Warsh is a board-certified pediatrician based in Los Angeles. After completing his residency at Children's Hospital Los Angeles, he became one of the few pediatricians to openly discuss vaccine safety concerns. He's the author of "Between a Shot and a Hard Place" and founder of Integrative Pediatrics and Medicine Studio City. We Also Discuss: Why Most Vaccines Were Never Studied Against True Placebos The Missing Vaccinated vs. Unvaccinated Research That Could End the Debate How Financial Incentives Drive Vaccine Recommendations The Autism Research That Doesn't Actually Exist MMR vs. Individual Protection: Why All Vaccines Aren't the Same The Hepatitis B at Birth Controversy for Low-Risk Babies Why Whooping Cough "Cocooning" Might Actually Increase Risk The Cleveland Clinic Flu Shot Study That Changed Everything mRNA Technology: What We Know vs. What We Don't After 4 Years Ultra-Processed Foods and the Real Driver of Childhood Illness Screen Time Strategies: Educational vs. Dopamine-Engineered Content The Social Contract Debate: Individual Rights vs. Public Health Thank You for Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Joel Gator Warsh Newsletter: https://raisingamazingplus.com/ Instagram: https://www.instagram.com/drjoelgator/?hl=en Website: https://raisingamazingplus.com/inner-circle/
What if the device in your pocket is secretly sabotaging your metabolism, sleep, and longevity? In this episode of Extend, I sit down with Dr. Rupy Aujla, a medical doctor turned lifestyle medicine pioneer who reversed his own heart condition through food and lifestyle changes alone. We explore the "cocaine phone vs. kale phone" strategy for digital wellness, why fiber maxing on TikTok is backfiring, and how to get 10 servings of vegetables daily without thinking about it. He also reveals his three-pillar framework for optimal health. Dr. Rupy Aujla is a medical doctor with over 15 years of experience, bestselling cookbook author of "Healthy High Protein," and founder of The Doctor's Kitchen app. After reversing his own atrial fibrillation through lifestyle medicine, he left the NHS to help millions of people worldwide cook their way to better health through evidence-based nutrition and functional medicine principles. We Also Discuss: The "Cocaine Phone vs. Kale Phone" Strategy for Digital Detox Why Fiber Maxing on TikTok Is Making People Sick The Three-Pillar Framework: Protein, Gut Health, and Anti-Inflammatory Eating How Dr. Rupy Reversed Heart Arrhythmia Without Surgery The "Just One More" Philosophy for Adding Vegetables Why 5-a-Day Was Completely Made Up (And What You Actually Need) Core Protein + Plant Partner + Topper: The New Protein Formula Silent Retreats: Resetting Your Dopamine in 3 Days Morning Light and Movement: The Ultimate Energy Hack Why Your Kitchen Is More Powerful Than Your Medicine Cabinet The Virtual Dr. Rupy AI Coach Revolution Thank You for Our Sponsors: Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Rupy Aujla: YouTube: https://www.youtube.com/@doctors_kitchen Instagram: https://www.instagram.com/doctors_kitchen/?hl=en Podcast: https://podcasts.apple.com/gb/podcast/the-doctors-kitchen-podcast/id1316938642
What if three minutes in cold water could give you more confidence than years of therapy? In this episode of Extend, I sit down with Kristin Weitzel, a breathwork expert and cold plunge coach who has certified over 325 instructors worldwide in her approach to nervous system regulation. We explore how to use breathwork to downregulate your nervous system instead of just surviving the cold, and why women shouldn't fear the recent controversy around cold exposure. Kristin reveals her "ICE" method (Intentional Cold Exposure) and shares the free tools that can transform your mental resilience starting today. Kristin Weitzel is a breathwork expert, Sherpa Breath and Cold founder, and certified sauna master who has been pioneering nervous system optimization for over a decade. She specializes in helping women and athletes use cold exposure and breathwork to expand their window of tolerance and build unshakeable confidence in all areas of life. We Also Discuss: Why the Anticipation of Cold Plunging Is Worse Than the Cold Itself The "ICE" Method: Intentional Cold Exposure for Life Success How to DJ Your Nervous System for Optimal Performance Why Most People Are Cold Plunging Wrong (And Spiking Cortisol) The 2x Breathing Technique That Changes Everything Cold Plunging vs. Cryotherapy Why Wim Hof Breathing Isn't Right for Everyone Sauna Secrets: The 3-Minute Rule Between Hot and Cold Free Cold Plunge Coaching Tools You Can Download Today Thank You for Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Function Health: The first 1000 get a $100 credit toward their membership. Visit www.functionhealth.com/drshah or use gift code DRSHAH100 at sign-up to own your health. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Kristin Weitzel: Website: https://www.sherpabreathandcold.com/ Instagram: https://www.instagram.com/kristinweitzelofficial/ Podcast: https://tr.ee/_aKc6TfA0K
What if the depression, brain fog, and weight gain you're experiencing isn't "just aging" but actually a treatable hormone deficiency? In this episode of Extend, I sit down with Sara Szal, MD, a Harvard-trained gynecologist who has revolutionized how we approach women's health. We dive into why 80% of women experience brain dysfunction during menopause, the shocking failure of conventional medicine's "birth control and antidepressants" approach, and Dr. Sara's "hormone therapy plus" model. Whether you're 35 and starting to notice changes or 65 wondering if you've "missed the boat," this conversation will transform how you think about aging as a woman. Sara Szal, MD is a Harvard-trained gynecologist, New York Times bestselling author of four books including "The Hormone Cure," and a leading authority on hormone optimization. With over 25 years of experience treating 25,000+ patients, she specializes in root cause analysis and personalized protocols for peak performance. We Also Discuss: The 100+ Symptoms of Perimenopause Most Doctors Don't Recognize Why Your Doctor Says Hormone Testing Is "Useless" (And Why They're Wrong) Bioidentical vs. Synthetic Hormones: What You Need to Know The 80% of Women Who Experience Cerebral Hypometabolism During Menopause Why FSH Levels Predict Alzheimer's Risk in Women Testosterone for Women: When It Helps and When It Hurts The "Cheating Nature" Argument Against Hormone Therapy (Debunked) Mitochondrial Health: The Key to Reversing Biological Age Hot vs. Cold Therapy for Mitochondrial Optimization Thank You for Our Sponsors: Vitaboom: For supplements you can trust and wellness solutions tailored to your health, visit https://vitaboom.com/ NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Sara Szal, MD: Website:https://www.saragottfriedmd.com/ Instagram:https://www.instagram.com/saragottfriedmd/
93% of Americans are metabolically unhealthy and don't even know it. In this episode of EXTEND, I sit down with Ben Azadi, metabolic health expert and New York Times bestselling author who transformed his life by losing 80 pounds after facing obesity, depression, and pre-diabetes at just 23 years old. We explore how one out of every four healthcare dollars is spent on diabetes and why your doctor probably isn't checking the one biomarker that could predict metabolic issues. We also dive into practical strategies for breaking free from the sugar-burning trap. Ben Azadi is a metabolic health coach, New York Times bestselling author of "Metabolic Freedom," and founder of the Keto Kamp podcast. After overcoming obesity and depression through lifestyle changes 17 years ago, he has dedicated his life to helping others achieve metabolic flexibility through ancient healing strategies like ketosis and fasting, combined with modern science. We Also Discuss: Why Fasting Insulin Is the Most Important Test Your Doctor Isn't Ordering The Whitehall 2 Study: 6-14 Years of Hidden Insulin Resistance "Mentally Obese": Understanding Depression's Connection to Food Why There Are No "Essential Carbohydrates" in Medical Textbooks Continuous Glucose Monitors: The Accountability Tool That Changes Everything The 44.4 Pound Weight Loss in 30 Days Case Study Metabolic Confusion: Why Diet Variation Beats Diet Dogma The Simple Swap from Sugar Burning to Fat Burning Single Ingredient Foods: The Beginner's Best Strategy Thank You for Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Function Health: Learn more and join using functionhealth.com/drshah. The first 1000 get a $100 credit toward their membership. Visit https://www.functionhealth.com/drshah or use gift code DRSHAH100 at sign-up to own your health. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Ben Azadi: Website: https://benazadi.com/ Instagram: https://www.instagram.com/thebenazadi/
What if I told you that an 18-year-old athlete had a testosterone level of 26 - when it should be near 1,000? In this episode of Extend, I sit down with Layne Kilpatrick, a pharmacist with over 30 years of experience who has been sounding the alarm about environmental toxins for years. We dive into the alarming decline in testosterone levels, how microplastics are literally everywhere, and why young, healthy men are showing up with fertility issues that would have been unthinkable decades ago. We also share actionable solutions to protect ourselves and our families. Layne Kilpatrick is a pharmacist and the driving force behind Hormone Specialist. He specializes in breaking down the science of hormones and everyday toxins, empowering both men and women to understand the root causes of hormone imbalances and take actionable steps to restore their vitality in a world filled with endocrine disruptors. We Also Discuss: Why Testosterone Levels Have Dropped 50% in 50 Years The 18-Year-Old Athlete with a Testosterone Level of 26 Microplastics vs. Nanoplastics: Size Matters for Toxicity The Paint on Glass Bottle Lids That's Contaminating Your Water PFAS: The "Forever Chemicals" Found in 100% of Breast Milk Samples The $200 Desktop Solution That Filters Microplastics HEPA Filtration: Why You Need Carbon Filters Too BPA-Free Doesn't Mean Safe: The Regrettable Substitution Problem Paper Cups and Straws: The Hidden Plastic Linings The Four-Step Action Plan to Protect Your Family Today Resources: Persistent Inert Substances Comparison: https://docs.google.com/document/d/1_kDzJzqFQN9m59IxfCtJKgc-n4qAlxgn/edit Thank You for Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Layne Kilpatrick: Website: https://www.hormonespecialist.net/ Instagram:https://www.instagram.com/hormonespecialist/
Did you know that functional practitioners have been using GLP-1 peptides safely for years—long before the Ozempic phenomenon hit mainstream medicine? In this episode of Extend, I talk with Dr. Tracey Stroup, a naturopathic doctor and peptide therapy expert, who reveals how the pharmaceutical industry's approach to semaglutide created unnecessary controversy. We dive into what peptides actually are, why your body might be deficient, and how the "dose everyone to the max and leave them there forever" approach completely missed the mark. We also discuss the functional medicine approach to peptide therapy, including proper dosing, cycling protocols, and why you need comprehensive support—not just a prescription. Tracey Stroup, ND is a naturopathic doctor with over 27 years in health and wellness. She's been using peptide therapy in her practice for 5 years and is passionate about educating both practitioners and patients on the proper use of these powerful therapeutic tools. We Also Discuss: What Peptides Really Are: Natural Biological Signals, Not Synthetic Drugs Why the Ozempic Craze Created Unnecessary Peptide Controversy The Functional Medicine Approach vs. Pharmaceutical Protocols How to Use GLP-1s Properly: Dosing, Cycling, and Off-boarding Why Most People Are Peptide Deficient (And Don't Know It) BPC-157: The "Wolverine Peptide" for Gut Health and Injury Recovery Growth Hormone Peptides: CJC, Ipamorelin, and Natural Hormone Balance Injectable vs. Oral Peptides: When and Why Each Route Matters Why DIY Peptide Therapy Can Backfire (And What to Do Instead) The Insulin Connection: Why Peptide Therapy Isn't Actually New Thank You To Our Sponsors: Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Tracey Stroup, ND: Website: https://courses.traceystroupnd.com/ftn-home Podcast: https://eatprayfaithwithtraceystroupnd.buzzsprout.com/ Instagram: traceystroup_eatprayfaith
What if the symptoms you've been told to "just deal with" during perimenopause could actually be addressed? In this episode of Extend, I sit down with Cynthia Thurlow, a nurse practitioner who left traditional cardiology to focus on women's health and metabolic medicine. We explore why the medical system has failed women during menopause, the critical biomarkers your doctor probably isn't checking, and how the misinterpretation of one major study has left generations of women suffering unnecessarily. We also discuss why LDL cholesterol might not be the villain it's made out to be and how hormone replacement therapy could be one of the most important interventions for long-term health. Cynthia Thurlow is a nurse practitioner and intermittent fasting expert. She's the author of "Intermittent Fasting Transformation" and hosts the "Everyday Wellness" podcast. She specializes in helping women navigate perimenopause and menopause through lifestyle medicine and bioidentical hormone replacement therapy. We Also Discuss: The Women's Health Initiative Disaster: How One Study Damaged Generations of Women Why Your "Normal" Fasting Glucose of 95 Means You're Already in Trouble ApoB and Lp(a): The Heart Disease Markers Your Doctor Isn't Checking Dutch Testing vs. Blood Work: Which Hormone Tests Actually Matter The $100 Calcium Score That Should Be Routine After 40 Why 60-Year-Olds CAN Start Hormone Replacement Therapy GLP-1 Medications: Beyond Weight Loss to Metabolic Healing The Intermittent Fasting Mistakes That Wreck Women's Hormones Pellet Therapy vs. Patches: The Hormone Delivery Debate Why Statins Are the Most Over-Prescribed Drugs in History Dysautonomia and HRV: The Nervous System Signals You're Missing The Gut-Menopause Connection No One Talks About Thank You for Our Sponsors: Pendulum: Use code DARSHAN or use the link https://pendulumlife.com/discount/DARSHAN to get 20% off IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Cynthia Thurlow: Website: https://www.cynthiathurlow.com/ Podcast: https://www.cynthiathurlow.com/podcast Instagram: https://www.instagram.com/cynthia_thurlow_/
The top 10 grossing drugs only help 1 in 4 to 1 in 25 people who take them. Yet they're still considered "evidence-based" and prescribed to millions. In this episode of Extend, I talk with Dr. Nick Norwitz, who reveals why you can't rely on population averages to fix your individual health problems. We explore why the medical system isn't designed to figure out what makes you unique, why "calories in, calories out" fails as a biological model, and how to become your own health scientist using the N=1 approach. We also discuss practical strategies for experimenting with your own biology, from testing ketogenic approaches to understanding why your results might be completely different from everyone else's. Dr. Nick Norwitz is a Harvard-trained MD/PhD who transformed his own health using metabolic interventions after conventional medicine failed him. He's known for his extreme self-experiments and scientific approach to personalized health optimization. We Also Discuss: Why Most "Evidence-Based" Treatments Don't Work for You The N=1 Approach: Becoming Your Own Health Scientist Why Population Averages Can't Predict Individual Results The Calorie Counting Myth That's Keeping You Stuck Ketogenic Diets: When They Work (And When They Don't) How to Design Your Own Health Experiments Why Bio-Individuality Trumps One-Size-Fits-All Solutions Escaping the "Normal" Trap in Modern Medicine Thank You To Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Nick Norwitz: Website:https://www.nicknorwitz.com/ YouTube: https://www.youtube.com/@nicknorwitzMDPhD/featured Instagram: https://www.instagram.com/nicknorwitz/
What if everything you've been told about preventing heart disease is only half the story? In this episode of Extend, I sit down with Dr. Joel Kahn, a pioneering preventive cardiologist who's spent decades challenging the traditional approach to cardiovascular medicine. We explore why the 1961 Framingham risk factors represent an incomplete picture of heart disease, and the hidden culprits damaging your blood vessels every day. We also dive into why a $100 calcium score should be as routine as a mammogram, how your cooking methods could be aging your arteries, and the surprising connection between erectile dysfunction and heart attacks. Dr. Joel Kahn is a preventive cardiologist, author, and founder of the Kahn Center for Cardiac Longevity. He is one of the few cardiologists advocating for plant-based nutrition and comprehensive lifestyle medicine. He's written multiple books including "The Whole Heart Solution" and hosts "Heart Doc VIP" podcast. We Also Discuss: Beyond Cholesterol: The 20+ Hidden Risk Factors Your Doctor Isn't Checking The $100 Test That Could Save Your Life (And Why Insurance Won't Cover It) Advanced Glycation End Products: How Your Barbecue Is Aging Your Arteries The Glycocalyx: Your Body's Secret Vascular Protection System Why Every Man with ED Needs a Calcium Score TMAO and the Dark Side of Choline Supplements Blood Pressure Devices That Work Without Pills The Trauma Surgeon with Perfect Arteries Despite Sky-High Cholesterol EECP Therapy: The NASA Technology Rebuilding Hearts Nitric Oxide: The Nobel Prize-Winning Molecule You're Probably Destroying ApoB vs. LDL: The One Number That Matters Most Why Listerine Might Be Sabotaging Your Blood Pressure Thank You for Our Sponsors: NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/ Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Joel Kahn: Website: https://www.drjoelkahn.com/ Instagram: @drjkahn
Why can't you open that jar anymore? Why does getting up from a chair feel harder than it used to? In this episode of Extend, I sit down with Dr. Amy Shah to explore the strength crisis happening to women in perimenopause. We dive into the simple tests that reveal where you're losing ground—and why most women are shocked by their results. We also share the exercise formula that actually works for perimenopausal women, honing in on the key fact that it has to be movement you enjoy, because sustainability beats intensity every time. Dr. Amy Shah is a double board-certified physician specializing in allergy/immunology and internal medicine, and author of I'm So Effing Tired. She's a leading voice in women's health, focusing on the intersection of hormones, gut health, and metabolism. We Also Discuss: The Grip Strength Test That Predicts Your Longevity (Most Women Fail) The Sit-to-Stand Test: Your Lower Body Strength Report Card Exercise Snacks: Why 10 Squats Every Hour Beats a 30-Minute Walk The Weighted Vest Mistake That's Wasting Your Time Why Jumping on a Trampoline Builds Stronger Bones Than Running Intermittent Fasting for Women: Why Daily Fasting Backfires Thank You To Our Sponsors: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Amy Shah: Website:https://amymdwellness.com/ Book: I’m So Effing TiredX: https://x.com/amyshahmd
What if I told you there's an organ in your body with more cells than the Milky Way has stars—and most doctors barely think about it? In this episode of Extend, I sit down with Dr. Zain Kassam, a gastroenterologist turned microbiome researcher who's pioneering how we understand the trillions of organisms living in and on us. We dive into why your gut bacteria aren't just bystanders—they're actively producing molecules that affect your mood, metabolism, immune system, and even longevity. We also explore the gut-brain connection, why not all probiotics are created equal, and how the microbiome influences everything from depression to skin health. Dr. Zain Kassam is a gastroenterologist, microbiome researcher, and Chief Medical Officer at Seed Health. He trained at McMaster University, Harvard, and MIT, where he pioneered clinical applications of microbiome science. He's led groundbreaking research on fecal transplants and develops evidence-based probiotic therapies. We Also Discuss: The Microbiome Revolution: From Forgotten to Life-Saving Why Your Gut Has More Cells Than the Milky Way Has Stars How Gut Bacteria Control Your Brain and Mood The Butyrate Connection: Your Microbiome's Master Molecule Why Most Probiotics Are Marketing Hype (And How to Choose Better) The 4D Framework: Diversity, Delivery, Do-Gooders, and Data Microbiome Testing: Crystal Ball or Expensive Guesswork? From C. Diff to Cancer: When Gut Health Becomes Life or Death The GLP-1 Secret: How Your Gut Makes Its Own Ozempic Post-Antibiotic Recovery: Rebuilding After the Nuclear Bomb Thank You for Our Sponsors: Pendulum: Use code DARSHAN or use the link https://pendulumlife.com/discount/DARSHAN to get 20% off IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Zain Kassam: X: https://x.com/DrZainSays/ Instagram: https://www.instagram.com/seed/ Get 25% off DS-01 with code EXTEND25 at Seed.com
Oxidative stress. Toxin overload. Immune dysfunction. These aren't separate problems—they're all symptoms of your body working overtime on one exhausting job. In this episode of Extend, I sit down with Dr. Nayan Patel, a pharmacist who's dedicated his career to understanding glutathione—the molecule your body produces more than any other. We break down the three proven ways glutathione protects you, why IV and oral supplements have been failing for decades, and the gene mutations that leave 20% of people unable to benefit from traditional glutathione therapy. Most importantly, we discuss the stable glutathione breakthrough that's helping doctors reverse decades of brain fog in minutes. Nayan Patel, Pharm.D, is a pioneering pharmacist and researcher who discovered the first stable form of glutathione in 2007. His 25-year journey to unlock this master antioxidant has led to revolutionary insights about aging, detoxification, and immune function. We Also Discuss: Why Your Body's #1 Job Is Slowly Killing You (And How to Take It Over) The 100+ Daily Toxins Your Liver Must Process (You Can't Avoid Them) Glutathione's Triple Threat: Antioxidant, Detox, and Immune Power Why IV Glutathione Fails: The Shocking Truth About What Really Happens The Gene Factor: 20% of People Can't Use Traditional Glutathione (Are You One?) From Brain Fog to Clarity: Why Some See Results in 5 Minutes Thank You To Our Sponsors: Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Nayan Patel, Pharm.D: Website:https://aurowellness.com/ Instagram: @aurowellness Book: https://aurowellness.com/glutathione-revolution/
Low energy, brain fog, and poor recovery aren’t just part of getting older—they’re often signs that your cells are underperforming. And one major reason? They’re starved for oxygen. In this episode of Extend, I talk with Dr. Scott Sherr, a hyperbaric medicine specialist who helps patients and doctors worldwide use oxygen therapy to restore cellular health. We get into what hyperbaric oxygen therapy (HBOT) actually does—not just more oxygen, but how it shifts gene expression, activates stem cells, and supports mitochondrial repair. We also discuss who shouldn’t jump into HBOT too soon, and why testing antioxidant capacity and metabolic function is essential before starting. This isn’t a quick fix—it’s a targeted tool that works when your system is ready. If you’re dealing with lingering symptoms or want to stay sharp and resilient long-term, this episode gives you a clear understanding of how HBOT fits into a true healthspan strategy. Dr. Scott Sherr is a board-certified internist and global expert in hyperbaric oxygen therapy, with over 20 years of clinical experience. He helps patients and physicians use HBOT to improve recovery, brain health, and long-term cellular function. We Also Discuss: The Real Goal: Longevity and Feeling Amazing Why Most Longevity Advice Misses the Mark Oxygen as Medicine? Inside Hyperbaric Therapy What Actually Happens in a Hyperbaric Chamber Can Oxygen Reverse Inflammation and Fatigue? Using Hyperbaric for Energy, Focus, and Recovery Thank You to Our Sponsor: IM8: Try IM8 today with a 30-day money back guarantee. You can get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Scott Sherr: Website: https://www.hyperbaricmedicalsolutions.com Instagram: https://www.instagram.com/drscottsherr/
Fatigue, brain fog, joint pain, blood pressure that won’t budge, these aren’t isolated symptoms. They’re your cells signaling that something’s off. In this episode of Extend, I sit down with Dr. Bill Rawls, a board-certified OB/GYN who now focuses entirely on cellular health. We explore why most chronic illness isn’t about your diagnosis, it’s about what’s happening inside your cells. We share the five things every cell needs to function, and what happens when they don’t get them. We also dig into stealth infections like Lyme and Epstein-Barr, and how they stay dormant for years until your body breaks down. Most importantly, we talk solutions: why herbs work when antibiotics don’t, how to support your immune system without overstimulating it, and what real healing looks like. Dr. Bill Rawls is a board-certified physician and author of The Cellular Wellness Solution. His personal health crisis with chronic Lyme led him to develop Restore180, a protocol that’s helped thousands recover from chronic illness by restoring cellular function. We Also Discuss: Why Chronic Illness Keeps Coming Back (And What We’re Getting Wrong) The 5 Things Every Cell Needs to Heal (You’re Missing at Least One) Lyme, EBV, Mold: How Hidden Infections Hijack Your Cells Sick Cells, Silent Symptoms: The Real Root of Chronic Disease Herbs vs. Antibiotics: Why One Heals and the Other Harms Thank You To Our Sponsors: Timeline: Upgrade your energy from within! MitoPure by Timeline helps power up your cells, supporting muscle strength, mental clarity, and overall vitality. Stay active, sharp, and strong at any age! Claim 10% off your first order now at timeline.com/DrShah Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Dr. Bill Rawls: Website: https://rawlsmd.com/ Program: restore180.comInstagram: @rawlsmd
Your doctor says your health problems are genetic, so you're destined for the same fate. But what if that's completely wrong? In this episode of Extend, I'm joined by Professor Tim Spector, one of the world's leading microbiome researchers, to reveal the truth: your gut bacteria have more control over your health than your genes do. We explore Tim's 30-year twin study that turned modern medicine upside down, the devastating effects of antibiotics on your internal ecosystem, and why ultra-processed foods are as dangerous as cigarettes. We also dive into why 95% of Americans are dangerously fiber-deficient, and how fermented foods can reduce inflammation like natural steroids. Professor Tim Spector is a genetic epidemiologist at King's College London, co-founder of Zoe, and author of multiple bestselling books on the microbiome. His research on 16,000 twins has revolutionized our understanding of how gut health trumps genetics in determining health outcomes. We Also Discuss: (02:18) 30 Years of Twin Research: The Study That Changed Everything (08:35) The Antibiotic Crisis: Why Your Childhood Meds Are Still Hurting You (11:31) C. Diff and the First Clue About Good vs. Bad Bacteria (22:40) Why Your Gut Microbiome Matters More Than Your Genetics (30:30) The Hidden Connection Between Gut Health and Autoimmune Disease (35:39) Ultra-Processed Foods: The Modern Cigarette Industry (43:51) Why 95% of Americans Are Fiber-Deficient (And Obsessed with Protein) (58:58) The 30 Plants Challenge: Diversity Over Restriction (01:05:22) Sourdough Secrets: Real vs. Fake (Most Is Fake) (01:13:46) Inside the Zoe Kit: Personalized Nutrition Based on Your Biology (01:19:53) GLP-1 Drugs: The Perfect Window for Gut Health Reset (01:27:36) Prebiotics vs. Probiotics vs. Postbiotics: What Actually Works (01:41:29) The Food for Life Cookbook: 100 Recipes for Your Microbiome Thank You for Our Sponsors: TruNiagen: Whether you are looking to stay sharp, feel more energized or simple age better, go to https://www.truniagen.com/ IFit: If you are looking to elevate your home gym fitness experience with the best in fitness tech, choose IFIT. Go to https://www.ifit.com/NextHealth: Your destination for cutting-edge health optimization—from IV therapy to hormone balancing. Explore at https://www.next-health.com/IM8: Get 20% off your first order with code DRSHAH at https://im8health.com/discount/DRSHAH. Learn more about Dr. Shah: Website: https://www.drshah.com/ Clinic: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd/ Learn more about Professor Tim Spector: Instagram: @tim.spector Website: https://zoe.com/en-us Pre-Order Ferment