Few & Far Between: Conversations from the Front Lines of Drug Development

Welcome to Few & Far Between! Chris O'Brien, CEO of Biorasi, is your host for Conversations from the Front Lines of Drug Development - from clinical research and policymakers to biotech innovators and industry leaders.

Episode 59, Part One: Yochi Slonim, Co-Founder and CEO at Anima Biotech

What do software bugs and human cells have in common? Find out in today's episode of the Biorasi Few & Far Between podcast. Host Chris O'Brien welcomes Yochi Slonim, Co-Founder and CEO at Anima Biotech, to the podcast. Tune in to part one of this special two-part episode as we double-click on #AIagents, building neural networks, and syncing visual biology with real-world biology. Okay, let's start the podcast!

09-03
43:41

Episode 58: Jerry McLaughlin, CEO and Board Member at Life Biosciences

How does a biopharma background prepare you for the biotech playground? Find out in our latest episode of the Biorasi Few & Far Between podcast! Host Chris O'Brien welcomes Jerry McLaughlin, CEO and Board Member at Life Biosciences, for an insightful discussion on cellular rejuvenation, working hand in hand with a board of directors, and knowing when to walk away from a clinical trial. Tune in today!

08-14
44:43

Episode 57: Jim Brown, DVM, President and CEO of DURECT Corporation

Is the epigenome the "software" of the cell nucleus? Find out in our latest episode of the Biorasi Few & Far Between podcast! Host Chris O'Brien welcomes Jim Brown, President and CEO of DURECT Corporation, for a conversation on the importance of a pharmacoeconomic strategy, developing new treatments for alcohol associated hepatitis, and moving beyond what a single individual can do in clinical research. Tune in today!

07-22
44:53

Episode 56, Part Two: Michael Tolentino, MD, Co-Founder and Head Scientific Consultant, Aviceda Therapeutics

How do experienced troubleshooters solve a difficult problem? By asking the right questions first! Welcome back to part two of our conversation with Michael Tolentino, MD, Co-Founder and Head Scientific Consultant at Aviceda Therapeutics. Join host Chris O'Brien as he and Dr. Tolentino, explore the traits of top problem solvers, the power of communication, and how silos and "bad apples" can undermine today's biotechs. Okay, let's start the podcast!

07-15
39:28

Episode 55: Julio G. Martinez-Clark, CEO and Co-Founder at bioaccess®

How much do you know about clinical trials in Latin America? Take a deep dive with us as we explore the benefits and risks of running studies in this region. In our latest episode of the Biorasi Few & Far Between podcast, host Chris O'Brien welcomes Julio G. Martinez-Clark, CEO and Co-Founder at bioaccess®. Tune in as we spotlight the advantages of running studies in #LATAM - from data quality to speed to approval.

07-09
38:46

Episode 54, Part One: Michael Tolentino, MD, Co-Founder and Head Scientific Consultant, Aviceda Therapeutics

The challenge? Decoding the human immune system. Get ready to meet the top challenger on today's episode of the Biorasi Few & Far Between podcast. Host Chris O'Brien welcomes Michael Tolentino, MD, Co-Founder and Head Scientific Consultant at Aviceda Therapeutics, to the podcast. Tune in to part one of this special two-part episode as we explore Michael's start in ophthalmology, groundbreaking treatments in intra-retinal therapy, and the importance of being a great communicator. Okay, let's start the podcast!  

05-28
45:11

Episode 53: Frank David, Founder and Managing Director, Pharmagellan

How do mission, vision, and data analysis fit into today's biotech goals? Host Chris O'Brien welcomes Frank David, Founder and Managing Director of Pharmagellan to the podcast. Tune in as we explore R&D strategy, de-risking tactics, and how to think about valuation. Listen in to the latest episode of the Biorasi Few & Far Between podcast today!    

04-29
50:46

Episode 52: Joshua Kresh, Emily Michiko Morris, and Mark Schultz, IPPI

How does a biotech balance great science with IP security to tell their story? Find out on today's episode of the Few & Far Between podcast! Host Chris O'Brien welcomes Joshua Kresh, Emily Michiko Morris, and Mark Schultz from IPPI: The Intellectual Property Policy Institute. Tune in for a fascinating discussion on the dos and don'ts of IP protection. Listen to the latest episode today!

04-23
52:05

Episode 51: Dan Oliver, CEO and Founder, Rejuvenate Bio

How do you turn back the epigenetic clock for humans and their animal companions?  Host Chris O'Brien welcomes Dan Oliver, CEO and Founder of Rejuvenate Bio, to the podcast. Tune in as we take a deep dive into parallel clinical trials designed to address chronic, age-related diseases in people and their pets. Plus, we'll zoom in on the right corporate structure for biotech products and the benefits of brainstorming. Listen in to the latest episode of the Few & Far Between podcast today!  

04-03
55:05

Epsiode 50: Jonathan Rigby, Chairman and CEO, Sernova

Now on the Few & Far Between podcast: Did you know that one in ten people with Type 1 Diabetes (TD1) die from hypoglycemia? Today's guest, who has TD1, explains how he turned his passion for helping others into innovative treatments for diabetes and other chronic diseases. Host Chris O'Brien welcomes Jonathan Rigby, Chairman and CEO at Sernova, to the podcast. Listen in as we spotlight Jonathan's 30-year industry journey, the development of implantable bio-hybrid organs, and how to plan for your first 30 days in a new biotech role. Tune in today!

03-18
52:02

Episode 49: Eileen Faucher, Principal and Founder, Brass Tacks Health

Today on the Biorasi Few & Far Between podcast: What if you could read a story before its official release? Competitive intelligence gives you early access to information on emerging trends in clinical trials.   On today's episode, host Chris O'Brien welcomes Eileen Faucher. Eileen is the Principal and Founder of Brass Tacks Health, a company that provides insights that biotechs need to drive clinically-meaningful therapies. Listen in to get the ROI on competitive intelligence, concise communications, and helping patients find relevant clinical trials. Thanks for listening!

02-27
35:37

Episode 48: John Celebi, President and CEO, Sensei Bio

"You have to have the right people, the right team, and good science." - John Celebi, President and CEO, Sensei Bio Welcome back to Biorasi's Few & Far Between podcast. On today's episode, host Chris O'Brien welcomes John Celebi to the pocast. Be sure to tune in for insights into assembling a core management team and how to build openness and inclusivity into biotech company culture. Thank's for listening!

02-18
38:46

Episode 46: Ben Olds and Amy Fenollosa, Haven Human Asset Ventures

"There's that old saying, 'culture is how people behave when nobody's looking.' So, if you want to be effective, your [mission and value statements] have to be specific enough to actually guide behavior." - Ben Olds, Executive Coach and Managing Partner, Haven Human Asset Ventures Welcome back to Biorasi's Few & Far Between podcast. On today's episode, host Chris O'Brien welcomes Ben Olds and Amy Fenollosa from Haven Human Asset Ventures.  Tune in for an in-depth discussion on the challenges CEOs and other biotech leaders face in building a successful company culture - from guiding behavior to creating safe spaces for innovative ideas. Looking for more information? Be sure to check out the following titles recommended by Ben and Amy in this episode: "Thanks for the Feedback: The Science and Art of Receiving Feedback Well," by Douglas Stone and Sheila Heen  "Right Kind of Wrong: The Science of Failing Well," by Amy Edmondson

01-15
43:29

Episode 47 - Marc Lajoie, CEO at Outpace Bio

"If you bring powerful technology to a problem that is well understood, then you can really make a difference." - Marc Lajoie, CEO at Outpace Bio Welcome to the latest episode of Biorasi's Few & Far Between podcast. Join host Chris O'Brien and guest, Marc Lajoie, as they discuss how de novo proteins can be used to reprogram immune cells. Tune in today!

12-31
48:25

Episode 46: Dr. Carsten Rudolph, CEO and Managing Director at Ethris

"It's really a very important challenge we had from the very beginning, to see how to stabilize nanoparticles with the messenger RNA so they are not destroyed during nebulization." - Dr. Carsten Rudolph, CEO and Managing Director at Ethris Welcome to the latest episode of Biorasi's Few & Far Between podcast. Join host Chris O'Brien and guest, Dr. Carsten Rudolph, as they discuss the current state and bright future of nasal vaccine technology. Tune in today!

12-12
37:26

Episode 44: Jonathan Scheiman, PhD, Co-Founder and CEO at FitBiomics

"We don't endeavor to make elite athletes better. We endeavor to make society healthier." - Jonathan Scheiman, PhD, Co-Founder and CEO at FitBiomics Welcome to the latest episode of Biorasi's Few & Far Between podcast. Join host Chris O'Brien and guest, Jonathan Scheiman, as they discuss microbiome solutions for next generation health and longevity. Tune in today!

10-23
44:29

Episode 43: Isaac Stoner, Co-founder and CEO at Octagon Therapeutics

"I hope we're moving into the age of the generalist, where knowing how to learn and learning how to learn are more important than specialized knowledge." - Isaac Stoner, Co-founder and CEO at Octagon Therapeutics Welcome to the latest episode of Biorasi's Few & Far Between podcast. Join host Chris O'Brien and guest, Isaac Stoner, as they discuss immunology, how to build a company, and financing in the biotech world. Tune in today! 

09-12
39:18

Episode 42: Diana Azzam, PhD, Assistant Professor at Florida International University, Co-Founder at First Ascent Biomedical

“Our studies are open for those that have exhausted standard of care, and we're showing improved responses, and the data is promising. So, I really hope that as we scale up and generate more data, we can actually move to newly diagnosed patients.” - Diana Azzam, PhD, Assistant Professor at Florida International University, Co-Founder at First Ascent Biomedical Welcome to the latest episode of Biorasi's Few & Far Between podcast. Join host Chris O'Brien and guest, Diana Azzam, as they discuss technological innovations in guiding individualized patient treatments. Tune in today! 

07-16
36:14

Episode 41: Craig Serra, Head of Clinical Research Scientific and Technical Engagement, Flatiron Health

"It's amazing how many companies there are and how many opportunities for a kind of a match between a human that needs some help and a company that can help." - Craig Serra, Head of Clinical Research Scientific and Technical Engagement, Flatiron Health Welcome to the latest episode of Biorasi's Few & Far Between podcast. Join host Chris O'Brien and guest, Craig Serra, as they discuss improving and extending the life of every person with cancer and learning from those experiences. Tune in today!

05-23
35:24

Episode 40: Professor Justin Stebbing, Editor-in-Chief, Oncogene journal

"I learned very early on that the stupidest cancer cell was cleverer than the cleverest oncologist." - Justin Stebbing, Editor-in-Chief of Oncogene, previously the UK's first NIHR Research Translational Professor of Oncology, Professor of Biomedical Sciences, Anglia Ruskin University, Cambridge. Welcome to the latest episode of Biorasi's Few & Far Between podcast. Join host Chris O'Brien and guest, Professor Justin Stebbing, as they discuss insights into oncology, knowledge sharing, and the virtuous circle of translational research. Tune in today!

04-25
33:23

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