In this episode, we discuss the intricate relationship between Autism and speech & language, emphasizing the critical role of neuroscience in understanding these dynamics. The discussion begins by highlighting how speech and language are foundational to human evolution and social interaction, yet pose unique challenges for individuals with Autism. The episode explores the brain's key regions involved in these processes, such as Broca's area, responsible for speech production, and Wernicke's area, crucial for language comprehension. These regions are connected by the arcuate fasciculus, a white matter tract essential for language processing, repetition, and verbal working memory.The podcast also examines how the basal ganglia, particularly the dorsal striatum, contributes to speech fluency and motor sequencing, including the articulation of words. By integrating neuroscience, we gain insight into the biological underpinnings of communication difficulties in Autism, such as delays in language processing and the phenomenon of "choppy" speech, which are linked to less coherent organization within these neural pathways.The episode further unpacks the concept of neuroplasticity and its implications for Autism, emphasizing the brain's ability to adapt through practice and repetition, leading to habits. The discussion also touches on the role of the dorsal medial striatum in goal-directed learning and the dorsal lateral striatum in habit formation, illustrating how these areas influence speech and language acquisition. Additionally, the podcast explores the phenomenon of echolalia, often observed in Autistic individuals, as a potential mechanism for processing delays or as a result of cyclical loops in the basal ganglia.The interplay of neurotransmitters like GABA and glutamate is highlighted, explaining the excitation-inhibition imbalance often seen in Autism, which affects sensory processing and communication. By framing these challenges through the lens of neuroscience, the episode underscores the complexity of social interaction for Autistic individuals and the importance of understanding the brain's predictive and adaptive mechanisms to better support their needs.00:00 - Introduction to Autism and Speech02:02 - The Speaker-Receiver Dynamic in Autism04:02 - Visual Thinking and Processing in Autism06:18 - Neuroscience of Speech and Language08:20 - The Role of the Basal Ganglia in Speech10:39 - Echolalia and Sensory Processing Delays16:53 - Neuroplasticity and Speech Therapy17:22 - Reflexes, Inhibition, and GABA in Speech and Autism20:02 - Basal Ganglia Circuits, Motivation, and Echolalia from getting "stuck"24:03 - Language Acquisition and Rule-Setting in Autism27:47 - Energy, Learning, and Social Challenges30:15 - Contingency-Based Learning and Outcomes31:46 - Reviews/Ratings and Contact infoX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumYT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com
In this episode, we explore the intricate world of autism research with Jill Escher, a dedicated philanthropist, lawyer, and parent to two Autistic young adults. Jill's journey into Autism advocacy was sparked by her children's diagnoses, with no prior family history, leading her to significant roles like president of the National Council on Severe Autism and leadership at the Autism Society in the San Francisco Bay Area. Through the Escher Fund for Autism, she examines the causes beyond genetics, investigating how environmental and biological factors might alter gene expression, contributing to Autism's heritability.Jill challenges the conventional genetic focus in Autism research, arguing that it fails to explain the increasing prevalence of Autism. She delves into complex topics like epigenetics and transcriptional regulation, proposing these might unlock the heritability puzzle of Autism. Her research includes looking at how factors like general anesthesia can affect future generations. Escher also discusses the hurdles in Autism research, including scientific dogma and the influence of the neurodiversity movement, urging for a more comprehensive approach to address what she sees as a looming national health crisis.Jill Escher https://www.jillescher.comHarvard Presentation: https://harvard.zoom.us/rec/play/n1wZBC2hwCOid8oKlQJLJECY7cGS0YeQMNlaSaFqu2Iybo8ADCEzrdqP01Q3lXTBRX73GHgWdYZMg5RT.Vwh6LCxdweMaleLf?canPlayFromShare=true&from=share_recording_detail&startTime=1733338808000&componentName=rec-play&originRequestUrl=https%3A%2F%2Fharvard.zoom.us%2Frec%2Fshare%2Fy3NWE-vbqRQB-lnpZ33Gk7HsbiTJPzi4xjXdCDudRMYtdNFYYC-URWaix3xiYe1e.22MUxTE70Dl-Yz62%3FstartTime%3D1733338808000Other ResourcesAutism and the Womb https://youtu.be/NOVp4mIrougThe Relationship of the Placenta, Womb, and Development https://youtu.be/Mj5h5DOMcRw0:00 Intro1:18 Jill's Journey into Autism4:25 Jill's Family & Autism7:19 Research & Advocacy in Autism10:19 Genetic & Heritability Explanation13:05 Non-Genetic Factors; Epigenetics21:08 Anesthesia; Germ Cell; Proliferation26:29 Early Brain Development; Gene Expression; RNA; Molecular level27:56 Research needs; Genetics & Dead End data; Society & Preparation of Prevalence33:57 Rates of Autism & Future (& Current) Emergency38:16 Vaccination41:25 Migration; Excitation/Inhibition Imbalance; Functional Connectivity48:02 Barriers in Autism; Jill's Contact Information53:33 Reviews/RatingsX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumYT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com
In this episode, we delve into defining the Autistic Phenotypes, emphasizing that while these traits are straightforward to identify, understanding their depth and impact requires integrating real-life data and personal experiences. We explore the characteristics of repetitive behaviors, habits, restricted interests, and a rigid adherence to schedules, which are pivotal to the Autistic Phenotypes. We will also discuss the Basal Ganglia pathways, specifically how the direct and indirect pathways influence these behaviors, touching upon how these neural connections relate to both the strengths (Superpowers) and challenges (Superdeficits) faced by individuals on the spectrum.Our discussion extends into the biological and social aspects of autism, examining how the inherent biology of autism can lead to comfort within oneself, yet creates struggles when forced into societal norms. We'll address the notion of conflict within the nervous system, explaining how it responds reflexively to disruptions in established patterns or expectations. The episode will also cover the neurological underpinnings of autism, including the roles of dopamine, GABA, and the substantia nigra in modulating behaviors and habits. We'll connect these insights to the adaptive responses or the lack thereof, which are central to understanding why individuals with Autism might resist changes in routines or show intense focus on specific interests. Practical implications and the historical context from early Autism studies by Leo Kanner and Hans Asperger are revisited, offering a comprehensive view on how these traits manifest in real-life scenarios and affect social interactions00:00 Understanding Autistic Phenotypes: Repetitive behaviors, restricted interests, and adherence to schedules. Basal Ganglia & strengths (superpowers) and challenges (superdeficits).05:23 Neurological Mechanisms: Basal Ganglia's pathways (direct and indirect) & Autistic behaviors. Repetitive actions, learning, and habit formation; dopamine, excitation and GABA; Stemming and the discomfort with unpredictability in social contexts.10:39 "Motivation", Movement, and Social Interaction: "Motivation" and motor movements & the basal ganglia & Autism; Social interactions & unpredictable, significant challenges & predictability. The segment also links these neurological pathways to DSM criteria for autism, highlighting the interrelation between motor and social behaviors.15:55 Neuroplasticity and Adaptation: Neuroplasticity & the repeated strengthening of neural connections shape Autistic traits; adaptive responses managed by the prefrontal cortex, and resisting changes or adhere to routines. 20:52 Biological Energy: brain's energy management for learning and habit formation works in Autism; acetylcholine for focus, dopamine for persistenceX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumYT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuATikTok: (I don't love it) https://www.tiktok.com/@fromthespectrumpodcastemail: info.fromthespectrum@gmail.com
In this episode, we explore the connections between Autism and Parkinson's, focusing particularly on the basal ganglia and its substructures, notably the substantia nigra within the midbrain. We discuss how the substantia nigra, known for its high concentration of neuromelanin, plays a critical role in these disorders. The episode examines how neuromelanin, a dark pigment, not only absorbs all frequencies of light but also has antioxidant properties, binds metals, and acts as a neuroprotector. This discussion leads into the broader implications of environmental signals, particularly light, on human biology, touching on how modern changes in light exposure might affect these conditions.We examine the role of tyrosine in the synthesis of neuromelanin and its derivatives like dopamine, which are crucial for neural function. We look at how deficiencies or imbalances in these pathways could lead to the symptoms observed in Autism and Parkinson's, including motor function issues. The conversation also covers the direct and indirect pathways in the basal ganglia, explaining how these pathways facilitate or inhibit movement, respectively, and how their dysfunction can manifest in the characteristic motor symptoms of both disorders. We also touch on the significance of thyroid function, particularly the roles of T3 and T4 hormones, in brain development and neuron health, tying these elements back to the overarching theme of energy loss and transduction in both Autism and Parkinson's.Autism and Parkinson's are a lack of, or a loss of, energy.Biological Energy: Quantum Mechanisms, Water, DHA, and NF-kB: https://youtu.be/2-IA_gunXbwTree comparison https://youtube.com/shorts/cLu53oVRRjI0:00 Autism and Parkinson's; Basal Ganglia; Substantia Nigra; Neuromelanin; Internal Calculators2:15 Tyrosine; Chromophores; Aromatic Amino Acids3:50 Biological Energy; Mitochondria; Environmental Signals; Cytochrome C Oxidase; Autism Research Miss6:20 Deep Brain Stimulation6:48 Neuromelanin9:02 Reverse Engineer ATPase10:48 Tree Examples11:45 Hypoxia and loss of energy & dopamine12:26 Eyes, hair, & skin; RPE; efficiency & power; What is Light?13:58 Light; Information & Energy; electromagnetic; wave-particle duality; sunlight versus artificial light17:08 Thyroid; T3 & T4; Iodine18:31 Roles of T323:00 Loss of energy in the womb & Autism research25:00 Melanin + Water = Electrons26:40 Basal Ganglia; "Motivations" & Movements; Direct Pathway30:55 Indirect Pathway32:52 Go, No-Go; Action selection, learning & habits; fine motor skills34:18 Parkinson's and loss of timing & energy; modulating the two pathways & dopamine37:07 Reviews/Ratings & contact infoX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumYT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuATikTok: (I don't love it) https://www.tiktok.com/@fromthespectrumpodcastemail: info.fromthespectrum@gmail.com
Autism just magically shows up.In this episode, we explore neuroplasiticity in our biology for one common environmental change- Light. Please consider 1) Critical Thinking and 2) Curiosity as we travel upstream in the biological implications causing Autism. In addition, we will explore other common health conditions related to Light. These health conditions are dementia, type 1 diabetes, obesity, type 2 diabetes, cancer, and cardiovascular diseases.The episode will discuss light as an electromagnetic strip and how our biology uses this energy. We discuss the embryo, neuroectoderm (brain and skin), proteins being wide-band gap semiconductors, photoelectric effect, cytochromes and mitochondria, chromophores, and related topics."... I realized that all biochemistry is the bridesmaid to physics. I then realized that physics are how the business of cells gets completed. Light is the biophysical levers that control substrate level biochemistry in cells." - Dr. Jack Kruse(Start here) Regenerative Health with Dr. Max Gulhane and Dr. Jack Kruse https://www.youtube.com/watch?v=Ln3WszTq0uATetragrammaton with Rick Rubin, Jack Kruse, and Bill Gifford https://www.youtube.com/watch?v=EHe78j9UrMITetragrammaton with Rick Rubin, Jack Kruse, and Andrew Huberman https://www.youtube.com/watch?v=oK9_j6fa2P4Decentralized is the way (The Status Quo is NO GOOD) https://www.youtube.com/watch?v=VO4JwdXuXXsTryptophan Biosynthesis https://faseb.onlinelibrary.wiley.com/doi/epdf/10.1096/fj.04-2079revAutism and Vit Bs and Serotonin https://www.patreon.com/posts/quantum-19-74498277Autism and Melanin https://www.patreon.com/posts/quantum-45-83724567Regions of Interest:Atoms,Aromatic Amino Acids,Artificial Light,Chromophores,Cytochromes,Electromagnetic,Embryo,Folate Acid (and Folic Acid)Sunlight,Melanin (Neuromelanin),Melanocytes,Melanogenesis,Melanopsin,Mitochondria,Neuroectoderm,Neuroplasticity,Periodic Elements,Photoelectric Effect,Pro-opiomelanocortin (POMC)Proteins (wide-band gap semiconductors),Serotonin,Tryptophan Hydroxylase 1 and 2,Vitamins A, b9 (Folate/Folic Acids), B12, and D,WaterX: https://twitter.com/rps47586YTEmail: info.fromthespectrum@gmail.com
In this episode, we explore the Basal Ganglia. The basal ganglia are a group of subcortical nuclei that play a crucial role in orchestrating movement. They are involved in what's known as the 'Go, No-Go' decision-making process, where they help decide whether to initiate or suppress actions. This region is critical where motivation translates into action.When discussing "motivations," we must be cautious; motivations aren't consciously defined by us but by our nervous system, which operates based on learned behaviors, habits, and neural pathways. The nervous system is designed to conserve energy by automating responses, which explains why it favors habit formation over constant conscious decision-making. It responds based on what it has learned, including connections, habits, and the rules established by our internal calculators.General Description of the Basal Ganglia:Inputs: Caudate Nucleus and PutamenRelays: Globus Pallidus External (GPe) and Subthalamic NucleusOutputs: Globus Pallidus Internal (GPi) and Substantia Nigra Pars Reticulata (SNr)Modulator: Substantia Nigra Pars Compacta (SNc)00:00 - Defining the Autistic Phenotypes.00:17 - Exploration of basal ganglia, focusing on the dorsal striatum.00:40 - Explanation of connecting Autistic Phenotypes with behaviors and implications through biology.01:00 - Detailed description of the basal ganglia's role in subcortical functions.01:50 - Discussion on the relationship between eye and brain development.02:18 - Explanation of basal ganglia's role in motivation and movement convergence.03:02 - Insight into how the nervous system conserves energy and responds to known patterns.03:52 - Explanation of why change is hard due to basal ganglia functions.04:37 - paper on excitation-inhibition phenomena in autism.05:07 - Genetic implications in autism: SHANK3, Neuroexcin, Neuroligin,06:45 - Discussion on the enlargement of the dorsal striatum in autism.08:07 - Identification of the caudate nucleus and putamen as inputs to the basal ganglia.09:40 - Role of the putamen in motor skill acquisition and fine-tuning movements.11:59 - Connection between the putamen and Autism-related motor behaviors like stimming.13:30 - Discussion on Autistics preferring their inner world.16:04 - Importance of the substantia nigra and dopamine in human function.18:26 - Dopamine receptors and their roles in Autism.20:03 - Subdivisions of the substantia nigra and their functions.21:01 - Description of the globus pallidus and its role in basal ganglia circuits.22:29 - Feedback loops involving the globus pallidus and subthalamic nucleus.23:40 - Implications of delayed or inefficient signal loops in movement control.24:57 - Role of the thalamus in processing sensations.26:31 - Subthalamic nucleus as a major relay center for motor control.28:47 - Linking Autism criteria with basal ganglia function.30:20 - Coverage of all four criteria B symptoms related to Autism.32:14 - Morphology of neural connections in Autism.32:51 - Reviews and ratings.X: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumYT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuATikTok: (I don't love it) https://www.tiktok.com/@fromthespectrumpodcastemail: info.fromthespectrum@gmail.com
The biology that gives us Autism allows us to be comfortable within ourselves.Our biology orients the Autistic towards our internal state. This is more comfortable for the Autistic in comparison to the outside world. In this episode, we cover brain regions, networks, and internal calculators. All humans use these biological calculators. However, based on the living organisms unique structure of brain regions and networks (connections), it is easy to understand why people are different.Epinephrine & Glia https://www.sciencedirect.com/science/article/pii/S009286741930621XOther Resources: Autism and Adaptive Responses https://youtu.be/Zj3_e6ZjCGkAutism and Default Mode Network https://youtu.be/9CqyH4woB34Autism and Salience Network https://youtu.be/9ZbTztb3al8Autism and B.3 https://youtu.be/Ov_Bw--zzrQ00:00 - Introduction00:42 - Biology and Autistic Comfort03:05 - Salience Network Explanation05:06 - Attention Management in Autism08:35 - Default Mode Network in Autism09:47 - Introducing Internal Calculators & Neuromodulators; Neuroplasticity10:52 - Biological Responses in Autistic Behavior14:02 - Effort and Energy: The Role of Internal Calculators; Calculator for Effort vs. Outcome17:07 - Social Interaction and Energy Use20:23 - Dopamine and Internal Calculators; Reward Prediction Error as an Internal Calculator25:18 - Internal Calculators and Societal Norms; Impact of Social Expectations on Internal Calculators; NeuroplasticityX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumYT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuATikTok: (I don't love it) https://www.tiktok.com/@fromthespectrumpodcastemail: info.fromthespectrum@gmail.com
Understanding the roles of Thyroid with Autism & Parkinson's, and what is the missing link.Research misses the link. Do not rely on research to connect these conditions and point to the real cause. Both, Autism and Parkinson's, have two major factors, 1) clocked timing and 2) A loss of, or a lack of, energy.Two Questions are asked:1) What do you think Neuromelanin is?2) What do you think Light is?Maternal health and preconception testing for Autism https://youtube.com/shorts/C2yhaPoWdIYIodine: https://youtube.com/shorts/q3dv-bslEwQThyroid hormones and Autism https://youtube.com/shorts/SRnDzn4UvgcImpact of light on neurodevelopment and aging: Autism https://youtube.com/shorts/cLu53oVRRjIBasal Ganglia: our go no go area for learning & habits https://youtube.com/shorts/YWc8AxuGHHMBasal Ganglia: Motivation & Movements (you don't define Motivation, the nervous system does)https://youtube.com/shorts/5agnRtSC95UX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumYT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuATikTok: (I don't love it) https://www.tiktok.com/@fromthespectrumpodcastemail: info.fromthespectrum@gmail.com
Consider how the autistic phenotype might be judged. We spend more time in educational settings, but our interactions extend beyond these environments. Humans are social creatures, and we need to understand what individuals are trying to accomplish, especially in social settings. These two phenotypes show significant differences.
A Year in Review from previous episodes. 00:00 - Intro 00:42 - Warning Against Comparing Rates; why comparing autism rates across different time periods is misleading due to changes in diagnostic criteria and definitions.02:07 - Historical Context; the Bayh-Dole Act, DSM acceptance of Autism, and changes in vaccination schedules, affecting Autism definitions; Core Autism Characteristics04:30 - Educational Challenges; Describes the typical school day's structure as potentially overwhelming for Autistic individuals due to frequent subject changes.05:36 - Intense Focus; Autistic individuals might fixate on topics with abnormal intensity or focus, which is a hallmark of Autism.08:40 - The biology of Autism allows us to be comfortable within ourselves; contrasting with societal expectations.09:09 - Employment and Anxiety; Considers how the expectation to fit into social norms can lead to anxiety and challenges in employment for Autistic individuals.10:10 - ADHD and Autism; Challenges the notion of coexisting ADHD and Autism, 14:26 - Early Detection; UCLA study on very young children showing altered salience network connectivity, hinting at early signs of Autism.14:49 - Developmental Timing; emphasizes that Autism likely starts in the womb, suggesting prenatal development as a critical area for research.15:14 - Neurodevelopmental Perspective; Autism as underdeveloped or abnormally developed cells, linking it to broader neurodevelopmental disorders.16:03 - Comorbid Conditions: Explores the concept of Autism being associated with various other conditions due to shared developmental issues.16:47 - Biological Processes: cellular proliferation, differentiation, and migration in the womb, crucial for brain development.17:41 - Mitochondria and Autism18:30 - Oxytocin & Autism; oxytocin as a molecule of interest, particularly its pathways and their implications for social behavior in Autism.20:29 - Social Reward System; Explains how oxytocin and serotonin interaction in the brain contributes to the rewarding nature of social interaction, which might be lacking in Autism.21:21 - Serotonin Synthesis; Details the synthesis of serotonin in both the GI tract and the brain, mentioning the enzymes involved and their significance.22:34 - Tryptophan and Light; Discusses how light affects tryptophan, an amino acid precursor to serotonin, and its role in biological processes.23:33 - Supplementing Relationships; Explores how visual thinking and movies can serve as a form of interaction for Autistic individuals, offering comfort or learning.25:17 - Visual Learning; Highlights the concept of "thinking in pictures" and how it leads to accelerated learning or Autistic intelligence.27:47 - Autistic Comfort and Societal Expectations; Advises against forcing Autistic individuals into societal norms that don't align with their natural inclinations, emphasizing understanding and acceptanceX; https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumYT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com
In this episode, we discuss some difficulties with eye contact for the Autistic phenotype. Sensory processing and the rate of information comes fast, and this provides additional energy for an already challenging and exhaustive task. Humans are constantly extracting physical phenomena from the environment (sensations) and we process this information to inform our nervous systems (perceptions). Specifically in this episode, we discuss the differences between listening and speaking.X: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumemail: info.fromthespectrum@gmail.com
My guest today is Dr. Kristen Lyall, ScD. Dr. Lyall received a Doctor of Science in Epidemiology from Harvard School of Public Health. During her postdoctoral training, she received training in Nutrient Science at Harvard and Pediatric Epidemiology at UC-Davis MIND Institute's Autism Research Training Program. Currently, Dr. Lyall is an Associate Professor at Drexel University's A.J. Drexel Autism Institute – Modifiable Risk Factors Program.The overarching goal of the Modifiable Risk Factors program is to identify factors that can be changed to prevent or mitigate the adverse effects associated with Autism, thereby potentially improving outcomes for individuals and informing public health policy and practice. Dr. Lyall's expertise provides actionable tools for listeners to understand the environmental risks of Autism. By the end of the episode, we hope you gain insight into the identified modifiable risk factors for Autism.Dr. Kristen Lyall: https://drexel.edu/autisminstitute/about/our-team/all-staff/Kristen-Lyall/Dr. Lyall publications link: https://pubmed.ncbi.nlm.nih.gov/?term=Kristen%20Lyall&sort=pubdateECHO: https://echochildren.orgFish not Supplements: https://echochildren.org/research-summaries/fish-but-not-supplements-consumed-in-pregnancy-associated-with-lower-rates-of-autism-diagnosis-and-related-traits-echo-cohort-study-finds/Other Resources:Biological Energy: Quantum Mechanisms, Water, DHA, and NF-kB (Autism is a loss of energy- electrons, photons, protons)https://youtu.be/2-IA_gunXbw0:00 Dr. Kristen Lyall2:30 Her Journey into Epidemiology & Autism7:50 The Role of Epidemiology & Autism12:15 Modifiable Risk Factors17:32 Dietary Influences on Autism Risk; Eat more FISH (DHA!)22:53 Assessing Exposure & Risk Factors32:35 Immune & Hormonal Factors in Autism; Cytokines & Inflammation39:17 The Impact of Acute Events during Pregnancy44:45 Air Pollution & its Effects in Neurodevelopment; Oxidative Stress48:14 Current & Future Research; ECHO & EARLI56:34 Reviews/Ratings, Contact InfoX: https://x.com/rps47586YouTube: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAHopp: https://www.hopp.bio/fromthespectrumemail: info.fromthespectrum@gmail.com
In this brief episode, we discuss keeping up in the classroom during teacher lecture. Specifically, we discuss the delays in sensory processing, taking notes, visual thinking, and some challenges with keeping up. This is a pressing issue for Autistics, and in my opinion, education needs to do better for the Autistic phenotype. Autism and Education https://youtu.be/zQpNtvS-tWwX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumemail: info.fromthespectrum@gmail.com
For today's episode, we discussing transferring energy from the environment across our biology. We discuss a few quantum theories, atoms, molecules, water, DHA, and NF-kB. Life on Earth is driven by energy from the environment, and this could be missed with humans, and especially with developmental problems like Autism.Water Podcast 1: Rubin, Kruse, Huberman https://www.youtube.com/watch?v=0lBAcUMGIeI&t=43sWater Podcast 2: Gulhane and Kruse (Light changes the Physics of Water !) https://www.youtube.com/watch?v=l9UbguvfpysWater Podcast 3: Gulhane and Kruse https://www.youtube.com/watch?v=W5w0WainlMMhttps://www.plefa.com/article/S0952-3278(12)00147-0/abstracthttps://pmc.ncbi.nlm.nih.gov/articles/PMC5793004/#:~:text=Electrons%20exist%20in%20all%20matter,role%20in%20oxidation%2Dreduction%20reactions.Quantum-coherent energy transfer: implications for biology and new energy technologies https://pmc.ncbi.nlm.nih.gov/articles/PMC3385675/#:~:text=In%20the%20simplest%20picture%2C%20quantum,transport%20at%20the%20molecular%20scale.Quantum cognition: The possibility of processing with nuclear spins in the brain https://www.sciencedirect.com/science/article/abs/pii/S0003491615003243Role of semiconductivity and ion transport in the electrical conduction of melanin https://www.pnas.org/doi/10.1073/pnas.11199481090:00 Intro0:40 Quantum Biology, Coherence, Thermodynamics, Water, DHA, NF-kB, and transferring energy - Atoms & Molecules2:00 Oxygen and CCO; Mitochondria3:55 Quantum Biology; Environments influence Atoms & Molecules5:50 Coherence & States; Light guides Life on Earth; Light provides Energy after it hits Matter7:16 Modern Human Environments7:41 Quantum Thermodynamics; Melanin, Electrons; Rules9:03 Biophotons, Photons and Lux; Seasonal Impact11:15 Electrons & Mitochondria; Real sources of Energy12:00 Artificial Light versus 280nm-3100nm Light; Big Harma & GLP-1 sidebar14:16 Autism and Loss of Biological Energy; changes in Light15:43 Electrons in Biology; Water; Coherent Domains; Semiconductors17:15 DHA; Electron Efficiency; Cells; Photoreceptors and Converting Energy and Developing Nervous Systems (plural)19:20 Phylogeny of Oxytocin and DHA sidebar; pi-electons; DHA dictates DNA22:40 Jack Kruse Quote23:36 Cells, Tissues, & Synapses; Origins of Autism; DHA roles26:14 Autism and X, Y, Z comorbid conditions (plural); definitions of Autism (modern versus origins), Criteria29:23 DHA takeaways; efficiency31:41 NF-kB; creating the womb and nervous systems; Autism and Orbitofrontal Cortex (OFC)35:06 Reviews/Rating & Contact Info
These are comments about my opinion and experience with education- the classroom and the school day. There are many contrasts to the Autistic phenotype when it comes to the classroom and school day.Autism and Education https://youtu.be/zQpNtvS-tWwB.3 https://youtu.be/Ov_Bw--zzrQKanner Kids https://youtu.be/FjELhG5FKzsAsperger's Autistic Intelligence https://youtu.be/qygNL6wCrhgX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumemail: info.fromthespectrum@gmail.com
For today’s episode, Dr. Hanna Stevens joins me to discuss early prenatal factors of early brain development. Dr. Stevens received an MD and PhD in Neuroscience from the University of Illinois. Dr. Hanna Stevens leads the Psychiatry and Early Neurobiological Development Lab at the University of Iowa Carver College of Medicine. Dr. Stevens is a distinguished Professor of Psychiatry and holder of the Ida P. Haller Chair.Her work leads groundbreaking research into the molecular and cellular foundations of early brain development, and is pivotal in linking prenatal stress, environmental factors, and genetic influences on childhood behavior and the emergence of disorders. With a focus on the critical periods of pregnancy and early childhood, her research aims to revolutionize the diagnosis and treatment of conditions throughout the lifespan. By the end of this episode, we hope you receive valuable information about the Placenta, Womb, and Development.Dr. Hanna Stevens https://medicine.uiowa.edu/psychiatry/profile/hanna-stevensIowa Healthcare https://uihc.org/childrens/providers/hanna-e-stevensPsychiatry and Early Neurobiological Development Lab (PENDL) https://stevens.lab.uiowa.eduPublications https://stevens.lab.uiowa.edu/publications0:00 Dr. Hanna Stevens2:00 Journey into Neuroscience and Psychiatry8:13 Prenatal Development of Autism14:02 The significance of NF-kB in Brain Development23:10 Serotonin; Leukocytes as a window into our Biology; Cortisol29:02 Steroid Hormones and Stress & Development34:12 Methylation40:00 Cell Proliferation & Migration in Fetal Development; Antioxidants45:56 Oxidative Stress; Mitochondria; Antioxidants48:30 Quantum Biology/Physics** Me shaking my head at minute 48:50 is not intended at Dr. Stevens, but at myself because I tell myself not to keep going to the electrons and light for a Cause of Autism to guests53:19 Future Research & Dorsal Striatum; Volume; Brain Development1:00 Reviews/Rating; Contact InfoX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumemail: info.fromthespectrum@gmail.com
For today's episode, we go back to the origins of Autism. It seems necessary because of the recent shifts in what is Autism and the confusion in the rates of Autism. Autism was here in the 1930's, and it magically showed up in different areas of the world. The two-part series intends to remember the phenotypes that appeared and became known as Autism and Asperger's.It is my opinion, the recent shifts in defining Autism could be rooted in questionable intentions. Regardless, one goal of the podcast is understanding and explaining Autism. By the end of the episode, and by the end of the two-part series, I hope you gain understanding of the Autistic Phenotype.If the children described by Asperger in Autistic Psychopathy in Childhood were alive today, they would receive a smorgasbord of diagnosis.Introduction to the Podcast (00:00:00 - 00:00:41,320):Asperger's Work and Concept of Autism (00:00:41,320 - 00:02:21,040):Historical Context and Asperger vs. Kanner (00:02:21,040 - 00:05:10,520):Case Study: Fritz V. (00:05:45,080 - 00:11:25,920):Detailed case study of Fritz, highlighting social integration issues, motor delays, superior speech, and behavioral challenges.Discussion on how modern medicine might label Fritz with multiple diagnoses.Case Study: Harold L. (00:13:21,040 - 00:15:25,240):Description of Harold's struggles with school, social withdrawal, and the conflict between autistic capabilities and societal expectations.Case Study: Ernest (00:17:37,960 - 00:21:00,160):Ernest's case with normal development but severe academic struggles, social withdrawal, and unique learning styles, suggesting individual teaching methods for autistics.Case Study: Hellmuth L. (00:21:16,680 - 00:24:40,240):Helmuth's case with complications at birth, delayed development, obesity, and later sexual tendencies, linking these to environmental and light exposure changes.Common Features Across Asperger's Cases (00:24:49,600 - 00:26:29,720):Summary of common traits observed across Asperger's 200 cases, including eye gaze issues, peripheral vision, and social interaction patterns.Asperger's Insights on Autistic Intelligence (00:26:29,720 - 00:27:37,760):Discussion on the unique intelligence and original ideas in autistic children, introducing the concept of "Asperger's little professors."Reflection on Autism as a Phenotype vs. Disorder (00:27:37,760 - 00:29:12,680):Historical Figures and Autism (00:29:12,680 - 00:29:41,480):Speculation on whether historical geniuses might have had autistic traits, highlighting that autism could be viewed as a superpower in certain contexts.Conclusion (00:29:41,480 - 00:30:42,800):X: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumemail: info.fromthespectrum@gmail.com
For today's episode, we go back to the origins of Autism. It seems necessary because of the recent shifts in what is Autism and the confusion in the rates of Autism. Autism was here in the 1930's, and it magically showed up in different areas of the world. (Part 2 on Asperger's "little professors" next). The two-part series intends to remember the phenotypes that appeared and became known as Autism.It is my opinion, the recent shifts in defining Autism could be rooted in questionable intentions. Regardless, one goal of the podcast is understanding and explaining Autism. By the end of the episode, and by the end of the two-part series, I hope you gain understanding of the Autistic Phenotype.Leo Kanner: Autistic Disturbances of Affective Contact http://www.autismtruths.org/pdf/Autistic%20Disturbances%20of%20Affective%20Contact%20-%20Leo%20Kanner.pdf0:00 Intro0:45 Erwin Schrödinger Quote; Quantum Physics; Missing link in Medicine2:56 Kanner's Autistic Disturbances of Affective Contact; Demographics3:52 Ages; Boys versus Girls; Phenotypes; Family History6:26 Important consideration of Family History- electricity and nnEMF; general observation and important phenotypes9:30 Anticipatory Motor Adjustment; Reflexes; Sensory and Adaptive Responses13:32 Monotonous Repetitions; Sameness15:26 Spelling and Language18:20 Commands and Intrusions18:57 Autism, not Autism and ADHD; Intense Fixations & Neuroplasticity; Default Mode Network; Sameness24:00 Oblivious to Others; Inattentive- It's not ADHD, it's Autism27:39 Changes & More on Sameness & Repetitions30:10 Rote Memory; Gastrointestinal: Timelines and MilestonesX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumemail: info.fromthespectrum@gmail.com
For today's episode, Dr. Eric Weiss, MD, explains an exciting medical approach for Autism. Dr. Weiss, who holds board certification in Plastic and Reconstructive Surgery, is a notable figure in regenerative medicine. Dr. Weiss is a Veteran of the U.S. Navy. Dr. Weiss attended Duke University Medical School for his medical degree, completed his General Surgery Residency at the University of California, San Francisco (UCSF), and did his Plastic Surgery Residency at the University of Miami. He has a special interest in using regenerative therapies to address autism.Dr. Eric Weiss recounts his journey into innovative medical practices, moving away from conventional pharmaceutical treatments. As a father to Marston, his dedication to exploring treatments for autism stems from personal experience. Throughout his story, his enthusiasm for natural healing methods is evident. By the end of this episode, listeners should gain insight into a thoroughly researched medical intervention that's gaining traction in the autism community.Dr. Eric Weiss, MD: https://northfloridastemcells.comDr. Eric Weiss, MD: https://linktr.ee/neflpsEducating Marston: https://www.educatingmarston.comDisclaimer: This is not Medical Advice.0:00 Dr. Eric Weiss, MD1:55 Dr. Weiss's Medical Journey5:01 Intersection of Autism and Stem Cell Research12:09 Personal Experience as a Parent with Autism15:58 Understanding Umbilical Cord Blood Treatment22:39 The Process of Umbilical Cord Blood Donation25:55 The Science behind Stem Cell Healing32:31 Future of Regenerative Medicine34:24 Natural Healing and Lifestyle, Not Big Pharma36:56 Mitochondrial Function & Energy Production39:09 The Impact of Light on Health41:07 Understanding Inflammation & Modern Disease44:30 Stem Cell Therapy: Mechanisms & Effects48:41 The Future of Medicine: Beyond Pharmaceuticals54:14 Professional Transition into Stem Cell and Regenerative Therapy58:05 Exploring Cytokines & Interleukins; Patterns of Disease; Dr. Weiss's Contact Info1:07 Reviews/Ratings; Contact InfoX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumemail: info.fromthespectrum@gmail.com
For today's episode, Nicole Rincon, PA-C, returns to discuss the risks associated with Autism development. The conversation spans from before conception through to after birth. We'll explore how factors related to the mother can influence autism risk, and we'll look at specific tests and signs in the body (labs and biomarkers) that have been linked to Autism. Additionally, we'll cover environmental influences, dietary considerations, acute medical conditions and medications, seasonal patterns, and various other aspects to be mindful of.By the end of the episode, we hope you'll gain valuable insights to consider as you navigate pregnancy. Our goal is to educate listeners, especially those who are pregnant or planning to conceive, about these potential risk factors, equipping them with the knowledge to make informed decisions or to be more aware during these pivotal times.Nicole Rincon https://www.nicolerincon.com/nicole-rinconRossignol Medical Center https://rossignolmedicalcenter.com/doctors/nicole-rincon/TACA Info: https://tacanow.org/wp-content/uploads/2019/10/F-H-2-Nicole-Rincon-Beginning-Biomed.pdfTACA Talks: https://www.nicolerincon.com/videosX: https://x.com/NicoleRinconPAPublications https://rossignolmedicalcenter.com/articles-publications/#published-2024-2-articlesOther Resources: Autism and the Embryo, and expanding Artificial Light as a possible cause of Autismhttps://www.youtube.com/watch?v=NOVp4mIroug(See 18:36)https://www.youtube.com/watch?v=OtA-aMN7ziYDISCLAIMER: THIS IS NOT MEDICAL ADVICE.0:00 Nicole Rincon1:00 Understanding Pre-Pregnancy Risks4:02 Maternal Risks Factors for Autism6:53 Environmental Factors for Autism9:56 Alternatives to Common Medications12:58 The Role of Light & Seasonal Factors16:02 Serotonin & Autism18:56 Inflammation & Mitochondria22:08 Infections & Antibiotics25:08 Lab Work & Biomarkers for Maternal Health27:46 Tyrosine, Thyroid, & Iodine; Depression, Fatigue31:07 Folate & Methylation in Pregnancy; Autoimmune; Pregnancy Complications40:40 Amino Acids; Dietary Types & Autism; Personal Diets49:00 Eating Seasonally & Locally51:01 Post-Pregnancy Nutrition54:00 Breastfeeding versus Formula Feeding; Environmental Factors & Toxins, Plastics, Water1:00 The Role of Sunlight on Human Biology; Leptin & Hormones, Metabolism Accountant; Red Light1:02 Sun and Sunscreen; Beta-Endorphins, Cannabinoids, Hormones1:07 Concluding Thoughts on Health & FamilyX: https://x.com/rps47586Hopp: https://www.hopp.bio/fromthespectrumemail: info.fromthespectrum@gmail.com