Nobel Laureate and biochemist Katalin Karikó's groundbreaking work on COVID-19 vaccines earned her the Nobel Prize in Physiology or Medicine in 2023, alongside co-collaborator Drew Weissman. She's also the Scripps Institution of Oceanography's 2023 recipient of the Nierenberg Prize for Science in the Public Interest. Karikó, an adjunct professor of neurosurgery at the University of Pennsylvania, is best known for her research on messenger RNA — the genetic material that tells our bodies how to make proteins — and the development of mRNA COVID-19 vaccines. Karikó and Weissman invented the modified mRNA technology used in Pfizer-BioNTech and Moderna’s vaccines to prevent COVID-19 infection. In this program, Karikó talks about the progress and development of mRNA over the past six decades. Karikó will discuss the journey from the discovery of mRNA in 1961 to its groundbreaking milestone as the first FDA-approved mRNA product in the form of COVID-19 mRNA vaccines in 2021. Series: "Science in the Public Interest" [Health and Medicine] [Show ID: 39337]
What we eat -- and don’t eat -- is directly related to our health. Poor diets lead to poor health outcomes, including cancer. Dr. Donald Abrams, integrative oncologist at UCSF Osher Center for Integrative Medicine, is an expert on nutrition and cancer. Here Dr. Abrams discusses the issue of fruit juices. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 38816]
The world's population is aging. How can we improve the lives of older people, their families, and their communities? Alison A. Moore, M.D., UC San Diego, shares the impacts of studying healthy aging globally. From the World Health Organization (WHO) to the UN and locally in San Diego, learn how the world community is studying aging to improve health, equity, longevity and more. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 38425]
In this program, Yvette Flores, professor of psychology at UC Davis, discusses how to cope during a crisis like the COVID-19 pandemic, especially social stress and the impact of it on disadvantaged and marginalized groups. Series: "Critically Human" [Health and Medicine] [Humanities] [Show ID: 37074]
The world is facing a health crisis due to increasing rates of obesity and diabetes, and the consequences of this pandemic will accumulate over the coming decades. Simultaneously, climate change is accelerating and is already having devastating effects that will undermine our ability to feed the world’s growing population. In turn, our food systems contribute importantly to greenhouse gas emissions, water and land use, and multiple forms of pollution. Thus, a solution to feeding what will be about 10 billion people by 2050 diets that are both healthy and environmentally sustainable presents an opportunity to mitigate many global challenges. The EAT-Lancet commission addressed this challenge by defining healthy diets quantitatively, determining whether these can be produced within planetary boundaries for greenhouse gas emissions and other environmental factors, and identifying strategies to achieve these goals. Any solution must assume that we rapidly shift from fossil fuels to green energy. The commission found that global adoption of a flexitarian dietary pattern that could include up to about two servings per day of animal sourced foods, together with improvements in agricultural practices and reductions in food waste, would have major benefits for human health and allow us to stay within planetary boundaries. Achieving this will require the engagement of governments at all levels, civil society, and individuals. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Humanities] [Science] [Show ID: 37911]
Founded in 2006 by the UCSF Department of Orthopedic Surgery faculty and residents, the Institute for Global Orthopaedics and Traumatology, or IGOT, is celebrating 15 years of addressing global disparities in orthopaedic trauma care. This video highlights IGOT's incredible team and the programs that are dramatically changing surgical outcomes. Validating IGOT's global impact, the Wyss Medical Foundation - a long-time supporter of IGOT - renewed its commitment to our organization in 2021 with a five-year grant. To help support our mission or to learn more please click on igotglobal.org. Series: "The Institute for Global Orthopaedics and Traumatology " [Health and Medicine] [Education] [Show ID: 37736]
Founded in 2006 by the UCSF Department of Orthopedic Surgery faculty and residents, the Institute for Global Orthopaedics and Traumatology (IGOT) is recognized as one of the leading academic and global outreach initiatives in the field of orthopaedic trauma. IGOT empowers through education, engaging a sustainable academic-to-academic partnership model with low and middle-income countries. Our in-country SMART courses have trained thousands of surgeons. This initiative has been amplified through our digital learning platform, including bi-monthly webinars and our groundbreaking IGOT Portal. To help support our mission or to learn more please click on igotglobal.org. Series: "The Institute for Global Orthopaedics and Traumatology " [Health and Medicine] [Show ID: 37735]
This presentation examines how the fossil fuel and petrochemical industries have created climate emergencies that have threatened global food production, human health, and soil health. Experts explore the ubiquitous presence of chemicals in our food supply and the significant, cumulative impacts of extreme heat, pesticides, herbicides, and GMOs on agricultural communities, as well as the promise of regenerative agriculture. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Science] [Agriculture] [Show ID: 36858]
This presentation explores how climate-fueled catastrophic environmental events have, and will increasingly, force mass displacement of populations within and across borders. Notably, as described by the United Nations, refugees, stateless people, and the internally displaced often reside in climate change ‘hotspots’ and may be exposed to secondary displacement. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 36857]
Grosche International Inc. is in the business of tea and coffee products but also in the business of action. Action to take action, and better the lives of those who are not able on their own, teaching developing communities how to make, install and maintain water filtration systems and providing communities with the tools to succeed. Megan Buchter talks with CEO Helmi Ansari and teacher Matthew Mulhern about the mission of the company and inspiring a new generation of change makers. Series: "Education Channel" [Public Affairs] [Health and Medicine] [Business] [Show ID: 36368]
Manny Ohonme received his first pair of shoes at the age of nine. The gift left a lasting impression on the young Nigerian boy. Today, Ohnome is the founder of Samaritan's Feet, an organization dedicated to providing shoes to children in need. In this interview, he shares his personal story and explains how providing shoes is not just about comfort but a way to foster equity, health, education, and hope. Series: "Brain Channel" [Health and Medicine] [Humanities] [Show ID: 36268]
Almost 6 million people worldwide die from traumatic injuries every year. A quarter of those injuries result from traffic accidents and mostly affects young adults who provide for their families. The team from the UCSF Institute for Global Orthopedics and Traumatology provide training to surgeons around the world. The result have shown a 93% surgical success rate in preventing amputations. Series: "The Institute for Global Orthopaedics and Traumatology " [Health and Medicine] [Show ID: 36422]
Traumatic injuries are the largest health crisis in the world today. UCSF's Institute for Global Orthopaedics and Traumatology provides advanced surgical education for surgeons in developing countries to improve the level of orthopedic care. Series: "The Institute for Global Orthopaedics and Traumatology " [Health and Medicine] [Show ID: 36423]
Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence via a multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the human host populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35849]
Over the past two decades novel coronaviruses have spilled from the bat to the human population on three occasions. The first two breakouts in south China in 2003 and in Saudi Arabia in 2012 launched the SARS and MERS outbreaks, respectively. Both outbreaks were contained by aggressive case finding, contact tracing and quarantine activities. A third crossover of a novel coronavirus into the human population occurred in the fall of 2019. This event which is believed to have occurred around a wet market in Wuhan, China was unfortunately not efficiently contained and spread rapidly across China. Since its crossover events six months ago, the virus has infected over 4 million people and resulted in 300,000 deaths. This presentation by Dr. Chip Schooley, UC San Diego Professor of Medicine, focuses on the biology, pathogenesis and epidemiology of the SARS-2 coronavirus and containment efforts to date. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35846]
The rate of under 5 mortality was halved from 1960 to 1990 but more recently there has been a slowing in the reduction. Success varies by region, explains Dr. Rajesh Daftary. He identifies current progress in mortality reduction and identifies effective interventions. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 35577]
Infectious diseases have profound influences on the evolution of their host populations. In the case of humans, the host species has also shaped pathogen dynamics and virulence viaa multitude of factors from changes in social organization, group size, and exploitation of varied habitats and their animals and plant resources to agriculture, technology, rapid long-distance travel, medicine and global economic integration - which all continue to shape epidemics and the humanhost populations. This symposium will explore how infectious agents and humans have shaped each other over the eons. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 35848]
Digital health solutions can improve the health of all and provide equity in healthcare. Tim K. Mackey and Daniel Haders II define digital health, how it is being leveraged to fight COVID-19, the impact of big data and machine learning, as well the effects on the business environment for digital health and use cases from start ups working on COVID-19 solutions. [Health and Medicine] [Science] [Show ID: 35959]
What have we learned about COVID-19? George Rutherford, MD, MA Professor of Epidemiology & Biostatistics at UCSF explores human coronaviruses in general, SARS, MERS and the novel coronavirus, SARS-CoV-2. He outlines the emergence of SARS-CoV-2 and its associated disease (COVID-19) in Wuhan, China and the rest of the world. He also discusses individual-level prevention, population-level prevention and the impact on the future. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 35930]
Dr. Andi Tenner, Co-Director, UCSF WHO Collaborating Centre for Emergency and Trauma Care, looks at emergency care systems needed to ensure care for the acutely ill and injured. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 35576]