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Grow Everything Biotech Podcast
Grow Everything Biotech Podcast
Author: Messaginglab
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Grow Everything explores the world of biology as technology. Hosts Erum Khan and Karl Schmieder interview leaders and influencers biologizing industries with tools like synthetic biology, precision fermentation, bioprospecting, and more. These companies make biomaterials from waste, cosmetics that restore healthy hair and skin, and delicious cultivated foods in a bioreactor and so much more. Join us as we discuss the latest and greatest across biotech, engineered biology, entrepreneurship, and culture and how this transition is solving healthcare and climate change challenges.
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Biology may be the most important technology we take off planet, and Mario Maggio is building the hardware to prove it. The founder and CEO of Ambrosia Space joins Erum Azeez Khan and Karl Schmieder to explain why space bioprocessing has been stuck at 10 to 20 milliliters while bench scientists on Earth work at 250 milliliters and beyond, and what changes when a two and a half liter fed batch bioreactor with pH, dissolved oxygen, and total cell density sensors finally flies. Mario traces his path from aerospace propulsion and the Nova C lunar lander at Intuitive Machines to life support systems at Paragon and Axiom Space, and the realization that biology is the best CO2 scrubber, oxygen source, and chemical factory available for long duration missions where petroleum, farms, and easy resupply do not exist. The conversation digs into the engineering reality of fluids and gas in microgravity, why glass and ceramics never fly, the stainless steel and aluminum builds that replace them, the intentional and unintentional bacteria that come with building a bioreactor from scratch, and the NASA TechLeap winning CellSep continuous flow centrifuge that carries cells and secreted products into downstream processing without gravity. Mario also lays out the near term commercial case, from protein crystallization and monoclonal antibodies that behave differently in orbit to biofuels, vitamin production, medicines, and the big silver tanks that will feed astronauts because there will be no farms or cattle. He offers a candid read on artificial gravity gradients, why the Moon matters for building large vehicles in space, and why the same hardware that grows yeast for beer on Mars becomes the root of better biomanufacturing on Earth. Erum and Karl open with field notes from Bio Innovations North America in Omaha, including Midwest feedstock advantage, consortia momentum, the 30 percent of cost hiding in downstream processing, and why Smucker and Mars are actively scouting biotech innovators.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) Why Biology Is the Best Commercial Case for Space(00:04:52) Bio Innovations North America and the Midwest Bioeconomy(00:07:21) Why Smucker and Mars Are Scouting Biotech Innovators(00:11:42) Inside Ambrosia Space: Bioreactors Built for Orbit(00:15:24) Scaling Past 150 Milliliters: Space Biology's Volume Problem(00:18:12) Stainless Steel, Leaks, and Why Glass Never Flies(00:21:36) NASA TechLeap and the CellSep Continuous Flow Centrifuge(00:26:08) Protein Crystals and Monoclonal Antibodies Made in Microgravity(00:31:22) Artificial Gravity, Lunar Bases, and Closing the Loop on Life Support(00:36:12) Quick Fire: Space Food Reality, HAL, and Biologics in OrbitLinks and Resources:Mario MaggioAmbrosia Space LinkedInAmbrosia Space111. Space Genes and Subway Scenes: Chris Mason on Planning Life’s Next Big Leap93. Houston, We Have a Protocol: NASA's Kate Rubins on Biotech in Space187. One Small Step for a Microbe: Lynn Rothschild’s Leap from Astrobiology to Bioengineering at NASA185. Brick Happens: Chris Maurer of Redhouse Studio Redesigns Remote Living for Earth and Mars152. Crystals in the Cosmos: Varda Rewrites Drug Formulation in MicrogravityGrow Everything LinkedInTopics Covered:space biomanufacturing, Ambrosia Space, orbital bioreactors, microgravity biotechnologyHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media
Chef and entrepreneur Pierre Thiam joins Grow Everything to explain how fonio, a resilient ancient grain from West Africa, can become a platform for biodiversity, regenerative agriculture, food security, and farmer prosperity. Pierre traces his journey from studying physics and chemistry to discovering the kitchen as a larger system connecting culture, health, ecology, and economics. He shares why fonio is nutritionally dense, gluten free, drought resistant, fast cooking, and versatile, as well as how Yolélé is building aggregation centers and modern processing infrastructure while keeping cultivation knowledge and ownership with smallholder farming communities. The conversation explores how biotechnology can complement biodiversity, why flavor must lead climate friendly food adoption, how underutilized crops can create clean label ingredients and new commercial markets, and why food can serve as a powerful tool for diplomacy and cultural understanding. For founders, scientists, investors, and builders in the bioeconomy, Pierre offers a human centered model of innovation that begins with nature, respects generational knowledge, and uses technology to unlock solutions that have been in front of us all along.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) Why flavor must lead sustainable food adoption(00:07:00) Artificial intelligence for science and protein design(00:14:00) Pierre Thiam connects cooking, chemistry, culture, and diplomacy(00:21:00) What fonio tastes like and why chefs love its versatility(00:28:00) Scaling fonio through farmer centered supply chains and global markets(00:35:00) Human centered design for West African farming communities(00:42:00) Delicious first: the strategy behind climate friendly food adoption(00:49:00) Biodiversity, forgotten crops, and the future of food security(00:56:00) How biotechnology and local knowledge can work together(01:02:00) Building healthier diets and stronger farming communitiesLinks and Resources:Chef Pierre ThiamTeranga - Senegalese RestaurantYolélé FoodsThe Fonio CookbookChief Pierre Thiam Instagram197. What’s in Your Cart? A Grocery Store Walkthrough of Next-Gen Food Innovation196. Beyond the Red Tape: Greg Jaffe on Policy as an Accelerator for Bio-InnovationNew Evidence points to ‘Ghost DNA’Claude opens 10,000 free seats to scientistsDavid Kong's class - How To Grow Almost AnythingBioInnovations Events - For 25% off use code: Grow EverythingGrow Everything LinkedInTopics Covered:Fonio, West African cuisine, sustainable food systems, regenerative agriculture, food biodiversity, underutilized crops, food diplomacy, Bambara groundnuts, climate-resilient crops, YoléléHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media
Food technology is moving from farms and petrochemicals into bioreactors, fungi, engineered crops, and circular feedstocks. In this Grow Everything highlights episode, Erum Azeez and Karl Schmieder visit six stops across the grocery store to explore sweet proteins from Oobli, fermentation derived colorants from MycoFutures and Chromologics, the antioxidant rich purple tomato from Norfolk Healthy Produce, fungi based proteins from The Better Meat Co. and MyForest Foods, sargassum derived ingredients from Origin by Ocean, and the hard commercial work of getting emerging products onto retail shelves. For founders, scientists, investors, and builders across synthetic biology and sustainable materials, the central lesson is clear: fermentation is manufacturing, environmental problems can become valuable feedstocks, and biology wins when performance, taste, branding, and price are better for the customer.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) Food technology innovations hidden across the grocery store(00:01:57) Why fermentation should be understood as manufacturing(00:03:02) Oobli sweet proteins replace sugar with tiny amounts of protein(00:04:35) Fermentation creates powerful natural colors for food brands(00:06:20) The purple tomato brings biotechnology into the produce aisle(00:08:11) The Better Meat Co. grows nutrient rich mycoprotein in bioreactors(00:09:54) MyForest Foods turns oyster mushroom mycelium into bacon(00:11:15) Origin by Ocean transforms invasive sargassum into useful ingredients(00:12:34) Startup CPG explains what gets emerging brands onto shelves(00:13:50) Why biology must compete on taste, price, branding, and performanceLinks and Resources:22. Sweet Dreams Are Made of Proteins: Oobli's Ali Wing180. Fungi in Full Color: Ricky Cassini Reimagines Dye at Michroma181. Can Hue Believe It? Gerit Tolborg’s Quest for Pure Color at Chromologics33. Purple Reign, A Purple Tomato with a Genetic Twist, Nathan Pumplin of Norfolk Healthy Produce157. (Thanksgiving Replay) Meat the Future: How Paul Shapiro is Brewing Superfoods at Better Meat Co.126. Sizzling Success: Eben Bayer of MyForest Foods on Scaling Mycelium Magic175. Seaweed Is the New Oil: Mari Granström Builds Origin by Ocean167. From Scrappy to Scalable: Daniel Scharff Grows Startup CPGBioInnovations Events - For 25% off use code: Grow EverythingGrow Everything LinkedInTopics Covered:Food technology is moving from farms and petrochemicals into bioreactors, fungi, engineered crops, and circular feedstocks. In this Grow Everything highlights episodeHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media
Biotech is moving fast, but regulation, public trust, and infrastructure still shape how quickly new ideas reach the market. In this episode of Grow Everything, Greg Jaffe joins Karl Schmieder to explore the regulatory future of the bioeconomy, drawing on Greg’s experience in environmental law, consumer advocacy, and as the USDA’s chief regulatory officer. They discuss why founders need to think about regulatory strategy early, how production methods, product claims, and intended use can dramatically change the path through agencies like USDA, EPA, and FDA, and why clear oversight can help build the trust emerging technologies need to scale. Greg and Karl also examine the regional nature of biomanufacturing, the importance of rural infrastructure and local partnerships, and why the future of the bioeconomy will require coordinated policy, stronger market demand, international access, and regulatory pathways that support innovation while protecting public confidence.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00) Intro: Moderna cancer vaccine news, Sargassum in Miami, and K18’s viral hairball activation(00:13:00) Greg Jaffe’s path from environmental law to biotech policy(00:16:30) Why the coordinated framework for biotechnology still matters(00:20:00) What biotech startups need to understand about USDA, EPA, and FDA(00:25:15) How claims, intent, and language can change a regulatory pathway(00:28:15) Why public trust is essential for biomanufactured food and biotech products(00:31:30) How biotech regulation differs in the United States, Africa, and Southeast Asia(00:35:20) Why biomass and biomanufacturing are inherently local(00:38:00) Which bio based sectors may be ready to scale first(00:42:20) The role federal policy can play in making bio based products the defaultLinks and Resources:Greg JaffeJaffe Policy Consulting LLCU.S. Department of AgricultureBioPreferred Program - USDAWhat is it like to be a cucumber? - Mike LevinThe Merck/Moderna cancer vaccine: How does it work and what are potential barriers to wide use?Miami faces worsening seaweed problem as piles of algae wash up on beachesSPOTTED K18 Hair: a giant hairball rolling across NYCBioInnovations Events - For 25% off use code: Grow EverythingGrow Everything LinkedInTopics Covered:USDA regulation, FDA food regulation, GRAS process, cultivated meat regulation, precision fermentation, food safety policy, bioeconomy policy, agricultural biotechnology, ultra-processed foodsHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media
Industrial biotechnology has enormous potential to create resilient supply chains, high performance ingredients, and a more sustainable bioeconomy, but good science alone is not enough. In this episode of Grow Everything, Karl and Erum speak with Olivier Rolland about the economic and industrial realities of scaling biology. Drawing on his experience across Michelin, TotalEnergies, Toulouse White Biotechnology, and L’Oréal, Olivier explains why biotech ventures must align sustainability, performance, cost, and customer expectations from the beginning. The conversation explores how techno economic analysis, early process constraints, industrial partnerships, standardization, and supportive policy can reduce risk and move promising molecules from the laboratory into commercial production. Olivier also discusses the biomanufacturing investment gap in Europe, the importance of resilient value chains, the limits of direct fossil replacements, and the opportunity to develop new molecules that deliver the same or better functions by design.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and speak with the leaders and innovators using biology to change the world. Biology is the world’s oldest technology, and it can be engineered. So, what are we growing?Learn more at www.messaginglab.com/groweverythingChapters:(00:00:00): Music festivals, Mike Levin, and consciousness at every scale(00:07:00): Biotech news, Houston biomanufacturing, and the Michelin Guide analogy(00:14:00): Genome astrology, ingredient transparency, and food regulation(00:21:00): Olivier Rolland on L’Oréal, Scope 3 emissions, water, and resilient supply chains(00:28:00): Finding the sweet spot between performance, economics, and sustainability(00:35:00): Techno economic analysis, retrofit constraints, and industrial partnerships(00:42:00): Europe’s scale up funding gap and the emerging EU biotech framework(00:49:00): Coalitions, fragmented value chains, and practical commercialization(00:56:00): What sustainable aviation fuel teaches beauty about market pull(01:03:00): Isofunctional molecules, biotech myths, duckweed, and rapid scale upLinks and Resources:L'Oreal Advanced Biotech for SustainabilityEp. 156. When Matter Makes Decisions: Michael Levin on the Intelligence of Form"What's it like to be a Cucumber" New York Magazine article about Mike LevinBMS picks Texas for new $2.3B manufacturing campusBio-AI is All Atlases and Nowhere to Go by Jake Wintermute and American WetwareBioInnovations Events - For 25% off use code: Grow EverythingGrow Everything LinkedInTopics Covered:biomanufacturing, industrial biotechnology, sustainable materials, green chemistry, biotechnology commercialization, scope 3 emissions, defossilization, sustainable beauty, bio-based ingredients, bioeconomyHave a question or comment? Message us here:Text or Call (804) 505-5553Instagram / Twitter / LinkedIn / Youtube / Grow EverythingMusic by: Nihilore Production by: Amplafy Media






