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Get the latest from the labs, doctors and medical centers at the University of California so you can make the best health care decisions. Visit uctv.tv/health
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Ths discussion captures the experiences of parents raising neurodivergent children, emphasizing the importance of finding joy, fostering inclusion, and supporting sibling relationships. Parents share personal stories of resilience, from guiding neurotypical siblings to embrace their roles with love to advocating for inclusive school environments. They highlight the unexpected ways their children teach them patience and strength, as well as the deep sense of community that emerges when families, educators, and peers come together. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 40214]
Karen Christman, Sheila Chari, Stella Hurtley, and Robert Stephenson
explore academic publishing in stem cell research, focusing on reproducibility, collaboration, and public communication. Editors from top journals discuss curating impactful research, sharing clinical trial data, and addressing challenges in scaling and standardizing therapies. They emphasize bridging silos, advancing precision regenerative medicine, and navigating open access publishing to responsibly propel the field forward. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39940]
This engaging panel discussion delves into the evolving representation of autistic characters in literature, comics, and pop culture, featuring authors and creators who bring authentic perspectives to their work. The conversation highlights the importance of intentionality in storytelling, challenges stereotypes, and explores the nuances of portraying neurodiverse experiences with depth and empathy. Panelists share personal journeys, writing inspirations, and the transformative power of seeing oneself reflected in stories, creating a thoughtful and inclusive dialogue that resonates with readers of all ages. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Arts and Music] [Show ID: 40330]
The human body is made up of billions of cells. These cells are the basic building blocks of life, and they work together to form tissues, organs, and systems that enable our body to function and carry out various activities. Each cell has its own specific function and role in maintaining the overall health and functionality of the body, but how do these cells know what to do? Researchers at UC San Diego and Hebrew University of Jerusalem share an intercontinental effort working to determine just that. Alon Goren and Itamar Simon discuss some of the work they are doing to learn more about the human body beyond the cellular level. [Health and Medicine] [Science] [Show ID: 40516]
What's the secret to supporting a sharp mind at any age? In this program, Dr. Nancy Isenberg discusses the latest science-based practices to promote brain health and resiliency as we age. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40508]
Learn about advancements in precision medicine, particularly the role of AI, stem cell research, and gene therapy. Experts highlight AI’s potential in personalized treatments, diagnostics, and patient care. Key topics include RNA targeting therapies, base editing for gene mutations, and using stem cells for disease modeling and regeneration. AI’s contribution to enhancing healthcare efficiency and decision-making is also explored, emphasizing its role in personalized medicine through large data sets.
Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39981]
A healthy microbiome can prevent disease and obesity. Dr. Sean Spencer discusses how a diet rich in fiber supports our health in various ways. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40458]
According to the World Health Organization (WHO) an estimated 1.3 billion people or 16% of the global population have a significant disability. A disability is a condition that can be mental or physical, and can affect a person's vision, movement, thinking, learning, communication, hearing, mental health or social relationships. However, not all disabilities are the same. Some disabilities are genetic, passed down from generation to generation, while others may have been caused by an incident out of the person's control. In this episode of Exploring Ethics, Professor Joseph Stramondo will discuss the narrative, identity and ethics of choosing disability. Series: "Exploring Ethics" [Health and Medicine] [Humanities] [Science] [Show ID: 40241]
Join us for a dynamic panel discussion where experts explore the contributions of Indigenous practices to modern agriculture. The conversation highlights traditional ecological knowledge, addresses gaps in food access, and proposes strategies to promote food sovereignty. Panelists examine how Indigenous wisdom and contemporary innovation create equitable, sustainable food systems, amplify Indigenous voices, and inspire collaboration for a resilient future. Series: "Future Thought Leaders" [Health and Medicine] [Agriculture] [Show ID: 40171]
Carissa Cascio, Ph.D., explores how autistic individuals perceive and process sensory experiences, focusing on internal sensations of the body, known as interoception, and their impact on emotions, anxiety, and sleep. Cascio highlights the challenges of heightened sensory awareness, including how it can disrupt rest, and underscores the importance of understanding these experiences to improve therapy and overall well-being. Cascio shares personal anecdotes and challenges myths about autism, emphasizing the rich internal worlds of autistic individuals. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Show ID: 40215]
Gordon Saxe, M.D., Ph.D., reveals the secrets to slowing down the aging process and living a healthier life. He uncovers how aging affects everything from our bones and muscles to our brain, leading to issues like memory loss, fatigue, and weakened immune responses.
How can you make choices today that could help you live longer and feel better? Saxe dives into groundbreaking research on caloric restriction, a powerful tool for extending lifespan, and how a plant-based diet can prevent chronic diseases and improve overall health. He also shares practical tips on exercise, stress management, and social connection that can help you stay sharp, strong, and energized as you age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40322]
Martin Kampmann, Ph.D., explores how CRISPR screening and induced pluripotent stem cell (iPSC) technology can uncover new insights into neurological diseases such as Alzheimer's. His lab uses CRISPR to identify genes that influence protein aggregation and cellular vulnerability, focusing on neurons, astrocytes, and microglia derived from human stem cells. Kampmann highlights the roles of mitochondria, autophagy, and other cellular pathways in disease progression, emphasizing the importance of understanding both protective and damaging processes. He also discusses the potential contributions of glial cells—especially microglia and astrocytes—to neurodegeneration, sparking ideas for therapeutic targets. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39461]
Anthony Lim, M.D., J.D., explores how small, intentional steps can lead to lasting behavioral change. Lim breaks down a simple, four-step framework—awareness, intention, action, and reflection—to help people achieve their goals, whether it's improving health, forming better habits, or making positive life changes. Through real-life examples and insights from neuroscience, he emphasizes the power of connecting with your deeper "why," taking action, and practicing self-compassion. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40323]
Christine Wu Nordahl, Ph.F., offers an insightful exploration into the unique needs and experiences of autistic teens, focusing on fostering inclusive spaces. Highlighting themes of gender diversity, underdiagnosis in girls, and the impact of societal perceptions, she emphasizes the importance of tailored support for neurodiverse individuals. Through powerful participant stories and an inspiring poem, Nordahl underscores the resilience and creativity within the autistic community. Her passionate advocacy for better diagnostic tools and inclusive interventions makes this talk a must-watch for anyone seeking to understand and empower autistic youth. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Show ID: 40213]
Frank Furnari, Ph.D., and Alexander Khalessi, M.D., M.B.A., discuss exciting advancements in brain cancer research, focusing on glioblastoma, an aggressive and challenging tumor. They highlight how specific genetic mutations drive tumor growth and how targeting these mutations could lead to new treatments. They also delve into cutting-edge therapies, including using light to activate drugs aimed at combating cancer. A central theme of the talk is the complexity and ever-changing nature of these tumors, which makes them difficult to treat. However, technological breakthroughs, like single-cell genetic sequencing and lab-grown tumor models, are providing scientists with valuable insights into tumor behavior, paving the way for more personalized and effective treatment options in the future. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39871]
Le Xu, Ph.D., examines the intricate processes underlying lung development and disease, with a focus on idiopathic pulmonary fibrosis (IPF). Xu explores the roles of genetic and cellular mechanisms, including the hedgehog pathway, FGF signaling, and epithelial-mesenchymal interactions, in driving lung fibrosis. Xu also highlights links between congenital diaphragmatic hernia (CDH) and lung development, suggesting that both mechanical and genetic factors contribute to lung hypoplasia. The discussion includes the development of advanced mouse models that replicate key aspects of human IPF, offering insights into fibrosis progression. Xu's research ultimately seeks to identify the causes of lung tissue abnormalities and pave the way for targeted therapies. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39460]
Carrie Bearden, Ph.D., delves into how sleep patterns and brain activity influence memory and cognitive abilities in individuals with neurodevelopmental disorders, including autism. Her research reveals that while these individuals tend to sleep longer, their brain activity shows unique differences, such as reduced slow-wave power, which may limit the cognitive benefits typically associated with sleep. Bearden also spotlights groundbreaking studies using advanced tools like stem cells and brain organoids to investigate how specific genes might drive these differences, offering hope for deeper insights and potential interventions. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 40211]
In this program, Dr. Jeffrey Gordon, Director of the Edison Family Center for Genome Sciences & Systems Biology at Washington University and the Scripps Institution of Oceanography's 2024 recipient of the Nierenberg Prize for Science in the Public Interest, discusses his research into the microbiome. Gordon is credited with founding the field of gut microbiome research. His transformative studies have demonstrated that human health and disease are shaped by the communities of microbes that live in the human gut. His body of work has opened up the vast new therapeutic potential for the microbiome, exemplified by his identification of ways to repair the gut microbiomes of children with malnutrition and restore their healthy growth. Series: "Science in the Public Interest" [Health and Medicine] [Show ID: 40154]
Madeline Oudin, Ph.D., is a scientist and mother on a groundbreaking mission to help her daughter, Margot, who has two de novo mutations in the SCN8A gene, which causes epilepsy. Margot's condition causes frequent seizures and developmental challenges. Determined to make a difference, Madeleine and her team are pioneering a cutting-edge genetic therapy that could one day transform treatment for Margot and others like her.
In this heartfelt talk, Madeleine shares how her scientific expertise and personal journey intersect, revealing the highs and lows of developing life-changing treatments. From innovative approaches using Antisense Oligonucleotides (ASOs) to the unexpected success of a ketogenic diet, this story is about resilience, hope, and the power of community. Series: "Autism Tree Project Annual Neuroscience Conference" [Health and Medicine] [Science] [Show ID: 40210]
Gloria Yiu, M.D., Ph.D., delves into the transformative potential of genetic editing technologies in addressing rare immune disorders, with a focus on CD3δ severe combined immunodeficiency (SCID)—a condition characterized by impaired T-cell development and severely compromised immune function. Leveraging her expertise as a physician-scientist, Yiu explores how CRISPR and other precision gene-editing tools can correct genetic mutations at the cellular level, potentially restoring T-cell production and immune resilience in patients with CD3δ SCID. Her presentation underscores the challenges and breakthroughs in treating such life-threatening conditions, emphasizing the role of interdisciplinary research, clinical innovation, and ethical considerations in advancing the frontiers of personalized medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40245]
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