https://www.nejm.org/doi/full/10.1056/NEJMoa2204233
SURMOUNT 1 Trial. The aim of this trial was to investigate the safety and efficacy of Tirzepatide, a novel GLP + GIP in people with obesity. We discuss the trial in this episode.
@ michaelsalzle Patients with diabetes and chronic disease are at high risk for kidney failure, cardiovascular events, and death. The FLOW trial looked at the safety and efficacy of semaglutide in patients with chronic disease and type 2 diabetes.
@michaelsalzlePreservation of your immune system, mind, and muscle
@michaelsalzle In this episode, we learn how to preserve our bones, bowel, circulation, hair, hearing, and hormones.
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@michaelsalzle. In this episode, we discussed pathways of aging. We discuss the importance of genes, AMPK, autophagy, metformin, foods that boost AMPK, autophagy, foods that boost autophagy, spermidine,epigenetics, and cellular senescence
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@michaelsalzle. In this episode we discuss nutrition 3.0. Epidemiology, clinical trials. The Mediterranean diet, the University of Wisconsin CR trial vs the NIH CR trial, carbohydrates, and protein.
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IG: @michaelsalzle. In this episode, we go into the broad topic of exercise. Exercise is considered the most powerful longevity drug. We review studies that underscore the importance of exercise. We also discuss the centenarian decathlon, and take a deep dive into zone 2 training.
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@michaelsalzle. The Long Game