Howards Blend

Discuss my thoughts on whether Dimethylglycine or Trimethylglycine is "better" for Homocysteine conversion to Methionine.This is strictly for educational purposes. The information in this video is not meant as a substitute for professional medical advice.Please like, comment and share if you find value in this video. Also, please ask any questions you have about supplements. I'll do a video reply as soon as possible.Resources: https://pmc.ncbi.nlm.nih.gov/articles/PMC4684116/https://cen.acs.org/articles/82/i3/METHYLMERCURY-TOXICOLOGY-PROBED.html#:~:text=%22Glutathione%20can%20be%20pumped%20out,brain%20as%20methylmercury%2Dglutathione.%22https://pmc.ncbi.nlm.nih.gov/articles/PMC4540061/https://www.sciencedirect.com/science/article/pii/S0163725821001182https://www.sciencedirect.com/science/article/pii/S0163725821001182 Image Resource:https://pmc.ncbi.nlm.nih.gov/articles/PMC6635095/ https://www.researchgate.net/figure/Overview-of-de-novo-glutathione-synthesis-Reduced-glutathione-or-GSH-is-a-tripeptide_fig2_5690064 https://lpi.oregonstate.edu/book/export/html/71 https://www.nature.com/articles/hr2011133 https://en.wikipedia.org/wiki/Serine_hydroxymethyltransferase - https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/methylenetetrahydrofolate-reductasehttps://chemtymology.co.uk/2020/11/27/cysteine-and-cystine/ https://fda.report/DailyMed/972f09a7-2aa1-4b1b-a6dc-2c4578a07803 https://www.thoughtco.com/definition-of-precipitate-604612 https://pubchem.ncbi.nlm.nih.gov/compound/Acetyl-p-benzoquinone-imine#section=3D-Conformer https://www.semanticscholar.org/paper/DRUG-METABOLISM-IN-THE-LIVER-Nguyen/4a29c6c4d433685a94b94602c012b8731cba5493https://pubchem.ncbi.nlm.nih.gov/compound/S-_Methylmercury_-L-Cysteine#section=2D-Structurehttps://keymerhealth.com/articles/seafood-mercury/https://onlinelibrary.wiley.com/doi/10.1155/2021/6564585 https://www.sciencedirect.com/science/article/abs/pii/S0304416519300133https://www.jbc.org/cms/10.1074/jbc.M111.265348/asset/822df563-eda2-4f48-a333-d01370a79e9c/main.assets/gr5_lrg.jpghttps://www.researchgate.net/figure/Betaine-metabolism-Metabolic-pathways-involving-betaine-BHMT-betaine-homocysteine_fig11_225081065https://www.acs.org/molecule-of-the-week/archive/c/l-cysteine.htmlhttps://biologydictionary.net/glutamic-acid/https://www.researchgate.net/figure/An-overview-of-the-reaction-catalyzed-by-SHMT-and-its-context-in-the-folate-cycle-A-The_fig1_338995871https://pubchem.ncbi.nlm.nih.gov/compound/5-Methyltetrahydrofolate#section=2D-Structurehttps://pubchem.ncbi.nlm.nih.gov/compound/Tetrahydrofolic-acid#section=2D-Structurehttps://pubchem.ncbi.nlm.nih.gov/compound/135398652#section=2D-Structure

This episode goes over the compounds of N-acetylcysteine (NAC) and Glycine, and how they are used to make Glutathione. Also, we go over a couple of use cases for Glutathione. This is strictly for educational purposes. The information in this video is not meant as a substitute for professional medical advice.Please like, comment and share if you find value in this video. Also, please ask any questions you have about supplements. I'll do a video reply as soon as possible.Resources: https://pmc.ncbi.nlm.nih.gov/articles/PMC4684116/https://cen.acs.org/articles/82/i3/METHYLMERCURY-TOXICOLOGY-PROBED.html#:~:text=%22Glutathione%20can%20be%20pumped%20out,brain%20as%20methylmercury%2Dglutathione.%22https://pmc.ncbi.nlm.nih.gov/articles/PMC4540061/https://www.sciencedirect.com/science/article/pii/S0163725821001182https://www.sciencedirect.com/science/article/pii/S0163725821001182 Image Resource:https://pmc.ncbi.nlm.nih.gov/articles/PMC6635095/ https://www.researchgate.net/figure/Overview-of-de-novo-glutathione-synthesis-Reduced-glutathione-or-GSH-is-a-tripeptide_fig2_5690064 https://lpi.oregonstate.edu/book/export/html/71 https://www.nature.com/articles/hr2011133 https://en.wikipedia.org/wiki/Serine_hydroxymethyltransferase - https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/methylenetetrahydrofolate-reductasehttps://chemtymology.co.uk/2020/11/27/cysteine-and-cystine/ https://fda.report/DailyMed/972f09a7-2aa1-4b1b-a6dc-2c4578a07803 https://www.thoughtco.com/definition-of-precipitate-604612 https://pubchem.ncbi.nlm.nih.gov/compound/Acetyl-p-benzoquinone-imine#section=3D-Conformer https://www.semanticscholar.org/paper/DRUG-METABOLISM-IN-THE-LIVER-Nguyen/4a29c6c4d433685a94b94602c012b8731cba5493https://pubchem.ncbi.nlm.nih.gov/compound/S-_Methylmercury_-L-Cysteine#section=2D-Structurehttps://keymerhealth.com/articles/seafood-mercury/https://onlinelibrary.wiley.com/doi/10.1155/2021/6564585 https://www.sciencedirect.com/science/article/abs/pii/S0304416519300133

Discussing a question I received asking where the blood brain barrier is located. In addition, we go over information about the blood csf barrier. This is strictly for educational purposes. The information in this video is not meant as a substitute for professional medical advice.Here's a link to the previous video on the blood brain barrier.https://spotifycreators-web.app.link/e/BQceRCwlKRbPlease like, comment and share if you find value in this video. Also, please ask any questions you have about supplements. I'll do a video reply as soon as possible.Resources:https://www.sciencedirect.com/topics/neuroscience/area-postrema#:~:text=The%20area%20postrema%20refers%20to,actions%20that%20lead%20to%20illness.https://qbi.uq.edu.au/brain/brain-anatomy/what-blood-brain-barrier#:~:text=The%20brain%20is%20precious%2C%20and,of%20the%20blood%E2%80%93brain%20barrier.https://www.cancer.gov/publications/dictionaries/cancer-terms/def/choroid-plexushttps://journals.lww.com/glaucomajournal/fulltext/2013/06001/production_and_circulation_of_cerebrospinal_fluid.5.aspxhttps://fluidsbarrierscns.biomedcentral.com/articles/10.1186/s12987-020-00230-3https://my.clevelandclinic.org/health/articles/22266-meningeshttps://pmc.ncbi.nlm.nih.gov/articles/PMC2821375/https://www.frontiersin.org/journals/neuroanatomy/articles/10.3389/fnana.2021.665803/full#F1https://pmc.ncbi.nlm.nih.gov/articles/PMC1871727/https://pmc.ncbi.nlm.nih.gov/articles/PMC7768803/https://pmc.ncbi.nlm.nih.gov/articles/PMC4120694/Image resources:https://www.cancer.gov/publications/dictionaries/cancer-terms/def/choroid-plexushttps://med.libretexts.org/Bookshelves/Anatomy_and_Physiology/Anatomy_and_Physiology_%28Boundless%29/11%3A_Central_Nervous_System/11.3%3A_Protection_of_the_Brain/11.3C%3A_Ventricleshttps://www.hydroassoc.org/understanding-the-choroid-plexus-function-location-and-its-role-in-hydrocephalus/https://www.researchgate.net/figure/blood-cerebrospinal-fluid-CSF-barrier-The-choroid-plexus-has-fenestrated-capillaries_fig1_325373010https://neuroscientificallychallenged.com/glossary/fourth-ventriclehttps://www.researchgate.net/figure/Area-Postrema-is-Anatomical-Marker-for-the-Subregion-of-NTS-of-Primary-Hypothetical_fig1_259320952https://www.rit.edu/spotlights/blood-brain-barrierhttps://www.cell.com/heliyon/fulltext/S2405-8440%2824%2911593-9https://www.aginganddisease.org/EN/10.14336/AD.2022.0130-1http://epilepsygenetics.net/the-epilepsiome/slc2a1-this-is-what-you-need-to-know/https://www.mdpi.com/2072-6643/16/14/2363https://www.mdpi.com/2072-6643/11/11/2636https://www.frontiersin.org/journals/cellular-neuroscience/articles/10.3389/fncel.2019.00282/fullhttps://teachmephysiology.com/immune-system/innate-immune-system/phagocytosis/https://oehha.ca.gov/chemicals/methylmercury-and-methylmercury-compoundshttps://www.mdpi.com/2073-4409/11/18/2823https://www.simplypsychology.org/brain-ventricles.htmlhttps://www.frontiersin.org/files/Articles/123479/fnins-09-00032-HTML/image_m/fnins-09-00032-g001.jpghttps://www.researchgate.net/figure/Cerebrospinal-fluid-flow-Cerebrospinal-fluid-is-mainly-produced-in-the-lateral_fig2_370857837https://www.physio-pedia.com/CSF_Cerebrospinal_Fluid

Going 2 Deep (two active ingredients) in this review of BUM Energy Drink, root beer flavor. This is strictly for educational purposes. The information in this video is not meant as a substitute for professional medical advice. Please like, comment and share if you find value in this video. Also, please ask any questions you have about supplements. I'll do a video reply as soon as possible. Image References: https://www.mdpi.com/1420-3049/27/12/3679 https://courses.lumenlearning.com/wm-biology2/chapter/neural-stimulation-of-muscle-contraction/ https://link.springer.com/referenceworkentry/10.1007/978-3-030-42634-7_52 https://www.researchgate.net/figure/Tripartite-synapse-Participation-of-the-astrocyte-in-the-regulation-of-synapse-activity_fig3_366464810 https://www.researchgate.net/profile/Francisco-Wandosell/publication/258282849/figure/fig1/AS:203001995239428@1425410855933/The-coordinated-action-of-glial-and-neuronal-purinergic-receptors-and-purines-in-the-CNS.png https://www.researchgate.net/figure/Schematic-drawing-of-ATP-and-adenosine-receptor-localization-on-different-cell-types-in_fig2_284132757 https://www.mdpi.com/1422-0067/22/1/320 https://brainstuff.org/blog/cellular-action-of-adenosine-receptors https://www.osmosis.org/notes/Motor_Nervous_System#page-16 https://www.sciencefacts.net/resting-membrane-potential.html https://www.researchgate.net/figure/Sodium-Potassium-pump-which-uses-ATP-to-pump-sodium-ions-out-of-the-cell-The-hydrolysis_fig2_273751706 https://jackwestin.com/resources/mcat-content/nerve-cell/nodes-of-ranvier-propagation-of-nerve-impulse-along-axon https://old-ib.bioninja.com.au/standard-level/topic-6-human-physiology/65-neurons-and-synapses/synaptic-transfer.html https://www.oist.jp/image/exocytosis-and-endocytosis-are-key-steps-vesicle-recycling-exocytosis-increases-surface-area https://www.sciencelearn.org.nz/images/2456-caffeine-and-adenosine-structure

This episode goes over my two cents about a question I received. Does lecithin cross the blood brain barrier more effectively than choline? This is strictly for educational purposes. The information in this video is not meant as a substitute for professional medical advice. Please like, comment and share if you find value in this video. Also, please ask any questions you have about supplements. I'll do a video reply as soon as possible. Information References: https://www.sciencedirect.com/science/article/abs/pii/S0197018615300802?via%3Dihub https://pmc.ncbi.nlm.nih.gov/articles/PMC1997116 https://lpi.oregonstate.edu/mic/other-nutrients/choline https://pubmed.ncbi.nlm.nih.gov/14938439/ https://pmc.ncbi.nlm.nih.gov/articles/PMC6835836/ https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/ Image References: https://cordancemedical.com/the-problem/blood-brain-barrier/ https://www.researchgate.net/figure/Molecular-characteristics-of-tight-junction-TJ-protein-complexes-at-the-blood-brain_fig1_363511691 https://www.sciencedirect.com/science/article/abs/pii/S1878818120304357 https://www.ncbi.nlm.nih.gov/books/NBK114308/ https://jissn.biomedcentral.com/articles/10.1186/1550-2783-4-5 https://www.ncbi.nlm.nih.gov/books/NBK594255/ https://pubchem.ncbi.nlm.nih.gov/compound/Choline https://pubchem.ncbi.nlm.nih.gov/compound/L-Tartaric-acid https://www.mdpi.com/2072-6651/8/11/326 https://pmc.ncbi.nlm.nih.gov/articles/PMC8235064/ https://www.examine.com/supplements/alpha-gpc/ https://pmc.ncbi.nlm.nih.gov/articles/PMC10025538/ https://pressbooks.calstate.edu/nutritionandfitness/chapter/6-2-phospholipids-and-sterols/ https://lpi.oregonstate.edu/mic/other-nutrients/choline

This is the second of a 2 part response to a question about lecithin vs choline. Here's the link to part 1. https://open.spotify.com/episode/2at2pXZQ02Wt9ZmYq3lczz?si=6exmen2-QjWM2fJ6aaItog Please like, comment and share if you find value in this video. Also, please ask any questions you have about supplements. I'll do a video reply as soon as possible. Information References: https://www.sciencedirect.com/science/article/abs/pii/S0197018615300802?via%3Dihub https://pmc.ncbi.nlm.nih.gov/articles/PMC1997116 https://lpi.oregonstate.edu/mic/other-nutrients/choline https://pubmed.ncbi.nlm.nih.gov/14938439/ https://pmc.ncbi.nlm.nih.gov/articles/PMC6835836/ https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/ Image References: https://cordancemedical.com/the-problem/blood-brain-barrier/ https://www.researchgate.net/figure/Molecular-characteristics-of-tight-junction-TJ-protein-complexes-at-the-blood-brain_fig1_363511691 https://www.sciencedirect.com/science/article/abs/pii/S1878818120304357 https://www.ncbi.nlm.nih.gov/books/NBK114308/ https://jissn.biomedcentral.com/articles/10.1186/1550-2783-4-5 https://www.ncbi.nlm.nih.gov/books/NBK594255/ https://pubchem.ncbi.nlm.nih.gov/compound/Choline https://pubchem.ncbi.nlm.nih.gov/compound/L-Tartaric-acid https://www.mdpi.com/2072-6651/8/11/326 https://pmc.ncbi.nlm.nih.gov/articles/PMC8235064/ https://www.examine.com/supplements/alpha-gpc/ https://pmc.ncbi.nlm.nih.gov/articles/PMC10025538/ https://pressbooks.calstate.edu/nutritionandfitness/chapter/6-2-phospholipids-and-sterols/ https://lpi.oregonstate.edu/mic/other-nutrients/choline https://www.researchgate.net/figure/molecular-structure-of-the-phosphatidylethanolamine-eluting-at-462-min_fig2_23771336 https://www.nature.com/articles/srep16787 https://www.researchgate.net/figure/Betaine-metabolism-Metabolic-pathways-involving-betaine-BHMT-betaine-homocysteine_fig11_225081065 https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.1109445/full https://ncbi.nlm.nih.gov/books/NBK554408/ https://www.researchgate.net/figure/A-simplified-illustration-of-the-homocysteine-metabolism-pathway-BHMT-betaine_fig1_341362341 https://www.researchgate.net/figure/Fig-2-The-nucleus-basalis-of-Meynert-innervates-the-entire-cerebral-mantle-with_fig1_327756974 https://www.researchgate.net/figure/The-human-cholinergic-system-Cholinergic-nuclei-are-primarily-located-in-numbered-cell_fig1_345346799

This is the first of a two part response to a question about lecithin vs choline. Stay tuned for part 2. Please like, comment and share if you find value in this video. Also, please ask any questions you have about supplements. I'll do a video reply as soon as possible. Information References: https://www.sciencedirect.com/science/article/abs/pii/S0197018615300802?via%3Dihub https://pmc.ncbi.nlm.nih.gov/articles/PMC1997116 https://lpi.oregonstate.edu/mic/other-nutrients/choline https://pubmed.ncbi.nlm.nih.gov/14938439/ https://pmc.ncbi.nlm.nih.gov/articles/PMC6835836/ https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/ Image Resources: https://cordancemedical.com/the-problem/blood-brain-barrier/ https://www.researchgate.net/figure/Molecular-characteristics-of-tight-junction-TJ-protein-complexes-at-the-blood-brain_fig1_363511691 https://www.sciencedirect.com/science/article/abs/pii/S1878818120304357 https://www.ncbi.nlm.nih.gov/books/NBK114308/ https://jissn.biomedcentral.com/articles/10.1186/1550-2783-4-5 https://www.ncbi.nlm.nih.gov/books/NBK594255/ https://pubchem.ncbi.nlm.nih.gov/compound/Choline https://pubchem.ncbi.nlm.nih.gov/compound/L-Tartaric-acid https://www.mdpi.com/2072-6651/8/11/326 https://pmc.ncbi.nlm.nih.gov/articles/PMC8235064/ https://www.examine.com/supplements/alpha-gpc/ https://pmc.ncbi.nlm.nih.gov/articles/PMC10025538/ https://pressbooks.calstate.edu/nutritionandfitness/chapter/6-2-phospholipids-and-sterols/ https://lpi.oregonstate.edu/mic/other-nutrients/choline https://www.researchgate.net/figure/molecular-structure-of-the-phosphatidylethanolamine-eluting-at-462-min_fig2_23771336 https://www.nature.com/articles/srep16787 https://www.researchgate.net/figure/Betaine-metabolism-Metabolic-pathways-involving-betaine-BHMT-betaine-homocysteine_fig11_225081065 https://www.frontiersin.org/journals/cardiovascular-medicine/articles/10.3389/fcvm.2022.1109445/full https://ncbi.nlm.nih.gov/books/NBK554408/ https://www.researchgate.net/figure/A-simplified-illustration-of-the-homocysteine-metabolism-pathway-BHMT-betaine_fig1_341362341 https://www.researchgate.net/figure/Fig-2-The-nucleus-basalis-of-Meynert-innervates-the-entire-cerebral-mantle-with_fig1_327756974 https://www.researchgate.net/figure/The-human-cholinergic-system-Cholinergic-nuclei-are-primarily-located-in-numbered-cell_fig1_345346799

Replying to a question about how the absorption of choline be improved. This was a response on a choline bitartrate video, so I used that ingredient to explain. Please like, comment and share if you find value in this video. Also, please ask any questions you have about supplements. I'll do a video reply as soon as possible. Image Resources: https://onlinelibrary.wiley.com/doi/10.1155/2021/6564585 https://socratic.org/questions/how-is-the-structure-of-a-villi-in-the-small-intestine-related-to-its-function

Answering a question regarding antihistamines and the effects on acetylcholine receptors. Please like, comment and share if you find value in this video. Also, please ask any questions you have about supplements. I'll do a video reply as soon as possible. Resources: https://www.jacionline.org/article/S0091-6749(06)02977-0/fulltext https://www.ncbi.nlm.nih.gov/books/NBK557790/ https://www.ncbi.nlm.nih.gov/books/NBK538188/ https://pubmed.ncbi.nlm.nih.gov/11164999/ https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14696 https://www.ncbi.nlm.nih.gov/books/NBK526010/ Image Resources: https://www.ebiohippo.com/en/aav-actone-gpcr-assay-kits.html https://www.science.org/doi/10.1126/science.aaw5188 https://meducatmedical.com/what-is-continence/

Discussing two questions I received. At what time should you take Citicoline? Also, does it work for the nervous system? Please like, comment and share if you find value in this video. Also, please ask any questions you have about supplements. I'll do a video reply as soon as possible.

Going over the taste of Ghost Energy Welch's Grape drink. Please like, comment and share if you find value in this video. Also, let me know of any supplements you’d like me to review.

Complete review of  Ghost Energy Welch's Grape flavored drink. Please like, comment and share if you find value in this video. Also, let me know of any supplements you’d like me to review.

Discussing the vitamins in Ghost Lifestyle's Ghost Energy Welch's Grape flavored drink. Please like, comment and share if you find value in this video. Also, let me know of any supplements you’d like me to review.

This video covers the sixth ingredient of Ghost Lifestyle's Ghost Energy Welch’s Grape flavored drink. Please like, comment and share if you find value in this video. Also, let me know of any supplements you’d like me to review.

This video covers the fifth ingredient of Ghost Lifestyle's Ghost Energy Welch’s Grape flavored drink. Please like, comment and share if you find value in this video. Also, let me know of any supplements you’d like me to review.

This video covers the fourth ingredient of Ghost Lifestyle's Ghost Energy Welch’s Grape flavored drink. Please like, comment and share if you find value in this video. Also, let me know of any supplements you’d like me to review.

This video covers the third ingredient of Ghost Lifestyle's Ghost Energy Welch’s Grape flavored drink. Please like, comment and share if you find value in this video. Also, let me know of any supplements you’d like me to review. #supplements #supplementreview

This video covers the second ingredient of Ghost Energy Welch’s Grape flavored drink. Please like, comment and share if you find value in this video. Also, let me know of any supplements you’d like me to review.

Welcome to the first supplement review of this channel. This video covers the first ingredient of Ghost Energy Welch’s Grape flavored drink. Please like, comment and share if you find value in this video. Also, let me know of any supplements you’d like me to review.

Replying to a comment I received asking how to decrease Choline intake. Disclaimer: This video is strictly for educational purposes. It is not a substitute for seeking professional medical help. Have Questions/ Comments? I can answer them in an upcoming episode. Instagram: https://www.instagram.com/howardsblend/ TikTok https://www.tiktok.com/@howardsblend Send me an email smbsupps@gmail.com Resources: https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/#h3 https://lpi.oregonstate.edu/mic/dietary-factors/L-carnitine#food-sources https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10302777/