Claim OwnershipIn the Know with Amol Sarva
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© Copyright 2024, Amol Sarva
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Amol Sarva's series with changemakers and innovators in longevity, tech, and ideas
86 Episodes
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Welcome to my series on OG NY Tech -- celebrating 30 years of NY tech ecosystem, from 1995 to now.
Owen Davis tells us how advertising powered early NYC tech and the big transition post-dot-com-crash to both consumer and enterprise tech superstars from New York.
Welcome to my series on OG NY Tech -- celebrating 30 years of NY tech ecosystem, from 1995 to now.
John Borthwick tells us the roots story of media and art and agencies at the heart of the early NY tech ecosystem and some of the players, and takes it through predictions for what to expect today.
Dr. B is an expert on gut health and shouting its power from the rooftops, both in his practice and writings but also through the company Zoe where he is US medical director. Some interesting news about coffee in this one.
Metabolic Health is the biggest medical breakthrough of the moment. Dive in!
The journey from food through digestion to your liver to energy stores and metabolizing work is the obsession of sports science - and hugely relevant to metabolic health overall. Let's get this perspective from research professor Derek Huffman at Einstein Medicine in New York.
Dive into metabolic health!
The different foods we eat and how they interact make a huge difference in disease progression, weight, and everything else. Dr. Jeff Alfonsi is a practicing physician for years, and chief medical officer of RxFoods which is designed to identify what you are eating and how to get better results.
Metabolic Health is the biggest medical breakthrough of the moment. Dive in.
Let's understand an overlooked dimension of the weight loss revolution underway -- the microbes in the digestive system themselves, potentially where GLP-1s come from in the first place. Duke's gut biome expert Maya Kaelberer gives us a guide.
Metabolic Health is the biggest medical breakthrough of the moment. Dive in!
Metabolic Health is the biggest medical breakthrough of the moment
Let's understand the cellular mechanisms and some of the most promising and widely used drugs in the world with one of the foremost researchers in the field, Matt Kaeberlein, formerly of University of Washington and now founder of longevity company Optispan
Metabolic Health is the biggest medical breakthrough of the moment
Mapping all the ways the GLP-1 drugs like Ozempic do and might work means we need to understand the biome and the efficacy of surgical interventions. We talk to Professor Randy Seeley who directs University of Michigan's Nutrition Obesity Research Center
Metabolic Health is the biggest medical breakthrough of the moment
Dr. John Buse has been at the forefront of diabetes research and endocrinology since before the first GLP-1 results started to become known. He studies the body's systems that seem to be at the core of how Ozempic and diabetes operate -- let's learn about the endocrine system and map out these system-level interactions
Metabolic Health is the biggest medical breakthrough of the moment
We have one of the world's experts on the liver - the place your body stores lots of energy from food, and distributes it onward to other systems, Dr. Waj Mehal of the Yale School of Medicine.
We lay out a map of the systems in digestion and metabolism, weight loss and exercise -- plus the different pathways that GLP-1s like Ozempic are using, and what else expected or unexpected is going on in our bodies
Metabolic Health is the biggest medical breakthrough of the moment
Get up to speed on the cellular biology with a fantastic overview from PhD scientist and founder of breakthrough pharma platform Cambrian Bio
Professor Matt Kaeberlein is an outspoken proponent of rapamycin, and pretty skeptical about virtually all the other interventions people talk most about. Here he lays out a pretty complete and persuasive model for why and how aging happens at all, and why some approaches are most likely to work.
1A rare MD at the cutting edge of the longevity field, Dr. Barzilai heads the Institute for Longevity Research at Einstein. We cover his unique contributions, especially the currently buzzy topic of metformin, as well as his work on the genetic luck of centenarians.
One of the more incredible research programs in longevity is regeneration: rebuilding and replacing failing organs with lab-grown cells. Jean Herbert at Einstein is working on regenerating your brain.
This founder has been part of so many of the exciting longevity startups, investments, and discussions that you simply must understand the world the way he sees it before taking a view about life extension. In this episode, you will.
Longevity superstar alert. A deep dive with one of the most recognized and longest-serving visionaries of longevity world.
After recording this episode, friends pointed out that I didn't cover big important parts of personal history that are covered here: https://en.wikipedia.org/wiki/Aubrey_de_Grey
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