JAMA Clinical Reviews

Author interviews that explore the latest clinical reviews.

Mpox Treatment Strategies, Clinical Presentation, and Diagnostic Approaches

Mpox is an evolving global health threat, and clinicians should be aware of characteristic signs and symptoms to ensure timely diagnosis and appropriate management. Author Jason Zucker, MD, MS, of Columbia University Irving Medical Center speaks with JAMA Deputy Editor Preeti Malani, MD, MSJ, about the transmission, diagnosis, management, and prevention of mpox. Related Content: Mpox Clinical Presentation, Diagnostic Approaches, and Treatment Strategies The Resurgence of Mpox in Africa Decline of Mpox Antibody Responses After Modified Vaccinia Ankara–Bavarian Nordic Vaccination WHO Announces Mpox Global Plan, Appeals for Funding

11-19
16:55

Calcific Aortic Stenosis: Symptoms, Diagnosis, and Treatment

Calcific aortic stenosis affects approximately 12% of people >75 years in the US and worldwide leads to more than 100 000 deaths each year. Catherine M. Otto, MD, PhD, of the University of Washington School of Medicine, Seattle, discusses the symptoms, diagnosis, and treatment of aortic stenosis with JAMA Deputy Editor Kristin L. Walter, MD, MS. Related Content: Calcific Aortic Stenosis

11-11
19:15

CAR T Cells and T-Cell Therapies for Cancer

CAR T cells are genetically engineered to express a receptor that recognizes and kills tumor cells. CAR T-cell products are now FDA approved for 6 hematologic malignancies. Author Jennifer N. Brudno, MD, National Cancer Institute, joins JAMA Deputy Editor Mary McGrae McDermott, MD, to discuss "CAR T Cells and T-Cell Therapies for Cancer: A Translational Science Review.” Related Content: CAR T Cells and T-Cell Therapies for Cancer Translational Science Reviews—A New JAMA Review

11-04
18:22

Diagnosis and Treatment of Peptic Ulcer Disease

Peptic ulcer disease affects approximately 1% of the population in the US, and H pylori is a common cause of peptic ulcer disease. Author Nimish Vakil, MD, a gastroenterologist from the University of Wisconsin, Madison, discusses current evidence regarding diagnosis and treatment of peptic ulcer disease with JAMA Deputy Editor Mary McGrae McDermott, MD. Related Content: Peptic Ulcer Disease

10-28
21:42

Strategies for Helping Patients Navigate High Prescription Drug Costs

High prescription costs are a major barrier to the optimal treatment of many health conditions. Prescribers need tools to help patients find the lowest drug costs. Author Hussain S. Lalani, MD, MPH, MSc, of Brigham and Women's Hospital and Harvard Medical School joins JAMA Senior Editor Anne R. Cappola, MD, ScM, to discuss "Strategies to Help Patients Navigate High Prescription Drug Costs." Related Content: Strategies to Help Patients Navigate High Prescription Drug Costs Strategies to Help Patients Afford Their Medicines in the US

10-21
12:33

Preexposure Prophylaxis (PrEP) Options for HIV

Even though highly effective medications are currently available to prevent HIV, there are about 1.3 million new infections worldwide each year. Monica Gandhi, MD, MPH, of the University of California San Francisco joins JAMA Senior Editor Karen E. Lasser, MD, MPH, to discuss preexposure prophylaxis (PrEP) for HIV. Related Content: Preexposure Prophylaxis (PrEP) for HIV What Is Doxycycline Postexposure Prophylaxis?

10-14
14:01

Update on Over-the-Counter (OTC) Contraception

In July 2023, the US Food and Drug Administration (FDA) approved Opill, a daily progestin-only oral contraceptive for over-the-counter sale to people of all ages. Daniel Grossman, MD, discusses this and more with JAMA Associate Editor Melissa A. Simon, MD, MPH. Related Content: Over-the-Counter Oral Contraceptives Over-the-Counter Oral Contraceptive Pills Over-the-Counter Progestin-Only Oral Contraceptives

10-09
00:03

Dialysis for Chronic Kidney Failure

Selection of hemodialysis or peritoneal dialysis and timing of dialysis initiation are influenced by patient symptoms, laboratory trajectories, patient preferences, and therapy cost and availability; shared decision-making is key. Jennifer E. Flythe, MD, MPH, from the University of North Carolina, discusses dialysis for chronic kidney failure with JAMA Deputy Editor Kristin L. Walter, MD, MS. Related Content: Dialysis for Chronic Kidney Failure

10-02
21:37

Diagnosis and Treatment of Chronic Spontaneous Urticaria

Chronic spontaneous urticaria affects approximately 1% of the general population worldwide, impairs patients’ quality of life, and is associated with multiple comorbidities. Pavel Kolkhir, MD, discusses the current evidence on the epidemiology, pathophysiology, diagnosis, and treatment of chronic spontaneous urticaria with JAMA Senior Editor Karen E. Lasser, MD, MPH. Related Content: Chronic Spontaneous Urticaria

09-26
17:29

Diagnosis and Treatment of Community-Acquired Pneumonia (CAP)

Community-acquired pneumonia is associated with approximately 740 000 hospitalizations and 41 000 deaths in the US annually. JAMA Review authors Scott A. Flanders, MD, and Valerie M. Vaughn, MD, MSc, discuss diagnosis and treatment of community-acquired pneumonia with JAMA Deputy Editor Mary McGrae McDermott, MD. Related Content: Community-Acquired Pneumonia

09-16
22:54

Scabies, Bedbug, and Body Lice Infestations

Infestations by ectoparasites such as scabies, bedbugs, and body lice are common. Diagnosis requires history, including social drivers of health such as living environment, and physical examination. Author Aileen Y. Chang, MD, of UCSF, joins JAMA Senior Editor Karen Lasser, MD, to discuss Scabies, Bedbug, and Body Lice Infestations: A Narrative Review. Related Content: Scabies, Bedbug, and Body Lice Infestations

09-09
18:41

Acute Pericarditis

Pericarditis accounts for up to 5% of emergency department visits for nonischemic chest pain in North America and Western Europe. JAMA Review author Paul C. Cremer, MD, MS, discusses the recommended treatments for acute pericarditis and more with JAMA Associate Editor David L. Simel, MD, MHS. Related Content: Diagnosis, Risk Stratification, and Treatment of Pericarditis

09-05
18:58

JAMA Highlights From ESC 2024

JAMA Editor in Chief Kirsten Bibbins-Domingo reviews 4 JAMA trials presented at this year’s European Society of Cardiology (ESC) Congress on antihypertensive continuation before elective surgery, potassium supplementation after cardiac surgery, pulmonary vein isolation for symptomatic atrial fibrillation, and a triple-drug combination pill for resistant hypertension in Africa. Correction: an earlier version of this podcast contained an error in the conclusion of the TIGHT K trial summary, which has been updated. Related Content: Continuation vs Discontinuation of Renin-Angiotensin System Inhibitors Before Major Noncardiac Surgery Low-Dose Triple-Pill vs Standard-Care Protocols for Hypertension Treatment in Nigeria Is a Low-Dose Triple-Drug Combination Pill Protocol the Answer for Hypertension Control in Sub-Saharan Africa? Potassium Supplementation and Prevention of Atrial Fibrillation After Cardiac Surgery Pulmonary Vein Isolation vs Sham Intervention in Symptomatic Atrial Fibrillation

09-02
10:04

Renal Cell Carcinoma

Renal cell carcinoma has an estimated lifetime prevalence of 2.3% for men and 1.3% for women in the US. Affected patients in early stages can have >94% cancer-specific survival. Author William Y. Kim, MD, of the University of North Carolina joins JAMA Associate Editor David L. Simel, MD, MHS, to discuss the epidemiology, clinical presentation, pathophysiology, and management of renal cell carcinoma. Related Content: Renal Cell Carcinoma

08-28
21:14

USPSTF Recommendation: Iron Deficiency During Pregnancy

Interview with Esa M. Davis, MD, MPH, USPSTF member and coauthor of Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content: Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy Anemic Data for Preventive Screening and Supplementation to Address Iron Deficiency Anemia in Pregnancy Screening for Iron Deficiency and Iron Deficiency Anemia During Pregnancy Iron Deficiency and Iron Deficiency Anemia During Pregnancy—Opportunities to Optimize Perinatal Health and Health Equity

08-20
09:13

Diagnosis, Treatment, and Prevention of Genital Herpes

Genital herpes is a common sexually transmitted infection that is caused by HSV-1 or HSV-2 and may result in ulcers, neonatal herpes infection, and increased risk of HIV acquisition. Author Christine Johnston, MD, University of Washington, discusses herpes infection and more with JAMA Deputy Editor Preeti Malani, MD, MSJ. Related Content: Genital Herpes

08-14
11:58

Perioperative Management of Patients Taking Direct Oral Anticoagulant Medications

Direct oral anticoagulants (DOACs) are commonly used to treat patients with atrial fibrillation and venous thromboembolism. Author James D. Douketis, MD, from McMaster University discusses with JAMA Deputy Editor Kristin L. Walter, MD, MS, the management of DOACs in patients undergoing an elective or emergency surgery or procedure. Related Content: Perioperative Management of Patients Taking Direct Oral Anticoagulants

08-12
25:39

Obesity in Adolescents

About 20% of adolescents in the US are living with obesity. Author Aaron S. Kelly, PhD, of the University of Minnesota Medical School joins JAMA Senior Editor Karen E. Lasser, MD, MPH, to discuss Obesity in Adolescents: A Review. Related Content: Obesity in Adolescents

08-05
18:56

Heat-Related Illness and Athletes

Exertional heat illness at its extreme may cause heat stroke and altered mental status (confusion, delirium, stupor, or unconsciousness), which can result in organ failure and death. Author Francis G. O’Connor, MD, MPH, discusses heat-related illness in athletes, including risk factors, prevention, symptoms, and management, with JAMA Associate Editor David Simel, MD, MHS. Current NWS Forecast Related Content: Heat-Related Illness in Athletes

07-25
16:08

Obesity Medications

New weight-loss drugs have transformed care for people with obesity. In this Clinical Reviews podcast, Robert F. Kushner, MD, MS, of Northwestern University Feinberg School of Medicine joins JAMA Deputy Editor Mary McGrae McDermott, MD, to discuss prescribing these drugs to improve health outcomes and minimize adverse effects in people with obesity. Related Content: Medications for Obesity

07-22
17:54

Angela Preda

Why only men?

05-15 Reply

Azura Bennett

Certainly! Author interviews diving into the latest clinical reviews offer an invaluable perspective.

12-21 Reply

ali bana

very useful 👍🌹

10-18 Reply

tim jennings

I'm unsure why this podcast episode was published. The host spends the entirety of the episode fighting over the word racism because he thinks racism is illegal and doesn't exist anymore. That's very clearly not the case (we just had Trump as a president, BLM marches, and insane COVID-19 disparities) so maybe he's not the right guy to be hosting something related to structural racism? The guest was okay but because the host was so caught up on the racism word, they got nothing accomplished over 15 minutes and made a fool of themselves in the name of JAMA.

03-04 Reply

Amirhossein Azari Jafari

that was such a wonderful story. I was on my cancer article while I was listening to this episode and honestly I shocked and it got me to think carefully. Dr. Stern, deep down in my heart, I wish u the best, Do not lose your hope and always be strong.

08-23 Reply

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