Lang zal je leven

<p>Klei drinken reinigt je lichaam, intermittent fasting helpt met afvallen en koffieklysma's zijn goed voor je darmen. Het wemelt tegenwoordig van de trends en hypes, die je zouden helpen om gezonder oud te worden. Maar hoe weet je wat klopt? Je kunt er eindeloos over lezen of alles zelf testen. Of je besteedt het allebei uit door deze podcast te luisteren.</p> <p>In <em data-stringify-type="italic">Lang Zal Je Leven</em> voorziet dokter Alexander je van de theorie over gezondheidsclaims. Praktijkexpert Tom ondervindt alles aan den lijve. Allemaal zodat jij kan vieren dat je alle kennis op een presenteerblaadje krijgt. Lang Zal Je Leven!</p>

Botox en fillers, schone schijn of ook functioneel?

Tom en Alexander duiken deze week in de wereld van spuiten, prikken en gladdere voorhoofden. Want online wemelt het van de claims: van “preventief botoxen” tot “botox is gif” en zelfs “je rimpels komen doordat je schedel krimpt”. Maar wat klopt en wat is vooral inspuitbare onzin? Kortom: eindelijk helderheid over iets waar je alles over denkt te weten tot je het écht gaat uitpluizen 😉. In deze aflevering:💉 Rimpels komen doordat je schedel krimpt📆 Preventief botox prikken helpt tegen rimpels🤕 Botox helpt bij migraine☠️ Botox is gif Tom stelt de vragen, Alexander fileert de feiten. Zodat jij voortaan weet: wat is verstandig, wat is onnodig, en wanneer moet je vooral niet met je gezicht naar de goedkoopste aanbieder rennen.🎧 Geproduceerd door Tonny Media👉 Volg ons op Instagram, TikTok en YouTube🥼Alle onderzoeken die in deze aflevering worden besproken vind je hier:See omnystudio.com/listener for privacy information.

12-02
32:21

Ademhaling: kan je écht je stress wegblazen?

Tom stort zich deze week op de ademhaling: van de Wim Hof-methode tot een intensieve breathwork class. Maar hoeveel invloed heeft ademen nou echt op stress, energie, sport en zelfs je mentale gezondheid? Alexander duikt in de fysiologie achter ademprikkels, paniek, neuzen, monden en mindset.Kortom: eindelijk helderheid over iets wat we elke dag doen zonder erbij na te denken, maar misschien zouden we dat juist wat vaker wel moeten doen.In deze aflevering:💨 Kan je stress verlagen door anders te ademen?👃 Waarom neusademhaling beter is dan mondademhaling🏋️ Kun je met ademhaling je energie en sportprestatie verbeteren?🧠 Is breathwork echt helpend bij depressie?Tom ademt, hyperventileert en experimenteert; Alexander fileert de feiten zodat jij voortaan weet welke ademhalingstechnieken nuttig zijn, en welke vooral lucht. 🎧 Geproduceerd door Tonny Media👉 Volg ons op Instagram, TikTok en YouTube🥼Alle onderzoeken die in deze aflevering worden besproken vind je hier: Brinkman JE, Toro F, Sharma S. Physiology, Respiratory Drive. [Updated 2023 Jun 5]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482414/ Fincham GW, Strauss C, Montero-Marin J, Cavanagh K. Effect of breathwork on stress and mental health: A meta-analysis of randomised-controlled trials. Sci Rep. 2023 Jan 9;13(1):432. doi: 10.1038/s41598-022-27247-y. PMID: 36624160; PMCID: PMC9828383. Bentley TGK, D'Andrea-Penna G, Rakic M, Arce N, LaFaille M, Berman R, Cooley K, Sprimont P. Breathing Practices for Stress and Anxiety Reduction: Conceptual Framework of Implementation Guidelines Based on a Systematic Review of the Published Literature. Brain Sci. 2023 Nov 21;13(12):1612. doi: 10.3390/brainsci13121612. PMID: 38137060; PMCID: PMC10741869. The Effect of Nasal Breathing Versus Oral and Oronasal Breathing During Exercise: A Review January 2020Journal of Sports Research 7(1) DOI:10.18488/journal.90.2020.71.1.10 Morgan SP, Lengacher CA, Seo Y. A Systematic Review of Breathing Exercise Interventions: An Integrative Complementary Approach for Anxiety and Stress in Adult Populations. J Holist Nurs. 2025 Dec;43(4):354-376. doi: 10.1177/08980101241273860. Epub 2024 Aug 16. PMID: 39150318. Siebieszuk A, Płoński AF, Baranowski M. Breathwork for Chronic Stress and Mental Health: Does Choosing a Specific Technique Matter? Med Sci (Basel). 2025 Aug 13;13(3):127. doi: 10.3390/medsci13030127. PMID: 40843749; PMCID: PMC12372116. Hopper SI, Murray SL, Ferrara LR, Singleton JK. Effectiveness of diaphragmatic breathing for reducing physiological and psychological stress in adults: a quantitative systematic review. JBI Database System Rev Implement Rep. 2019 Sep;17(9):1855-1876. doi: 10.11124/JBISRIR-2017-003848. PMID: 31436595. Lörinczi F, Vanderka M, Lörincziová D, Kushkestani M. Nose vs. mouth breathing- acute effect of different breathing regimens on muscular endurance. BMC Sports Sci Med Rehabil. 2024 Feb 9;16(1):42. doi: 10.1186/s13102-024-00840-6. PMID: 38336799; PMCID: PMC10858538. Xavier DM, Miranda JP, Figueiredo PHS, Lima VP. The effectiveness of respiratory muscular training in athletes: A systematic review and meta-analysis. J Bodyw Mov Ther. 2025 Jun;42:777-792. doi: 10.1016/j.jbmt.2025.01.010. Epub 2025 Jan 29. PMID: 40325755. HajGhanbari B, Yamabayashi C, Buna TR, Coelho JD, Freedman KD, Morton TA, Palmer SA, Toy MA, Walsh C, Sheel AW, Reid WD. Effects of respiratory muscle training on performance in athletes: a systematic review with meta-analyses. J Strength Cond Res. 2013 Jun;27(6):1643-63. doi: 10.1519/JSC.0b013e318269f73f. PMID: 22836606. Balban MY, Neri E, Kogon MM, Weed L, Nouriani B, Jo B, Holl G, Zeitzer JM, Spiegel D, Huberman AD. Brief structured respiration practices enhance mood and reduce physiological arousal. Cell Rep Med. 2023 Jan 17;4(1):100895. doi: 10.1016/j.xcrm.2022.100895. Epub 2023 Jan 10. PMID: 36630953; PMCID: PMC9873947. Banushi B, Brendle M, Ragnhildstveit A, Murphy T, Moore C, Egberts J, Robison R. Breathwork Interventions for Adults with Clinically Diagnosed Anxiety Disorders: A Scoping Review. Brain Sci. 2023 Feb 2;13(2):256. doi: 10.3390/brainsci13020256. PMID: 36831799; PMCID: PMC9954474. Chin P, Gorman F, Beck F, Russell BR, Stephan KE, Harrison OK. A systematic review of brief respiratory, embodiment, cognitive, and mindfulness interventions to reduce state anxiety. Front Psychol. 2024 Jun 12;15:1412928. doi: 10.3389/fpsyg.2024.1412928. PMID: 38933581; PMCID: PMC11203600. Zaccaro A, Piarulli A, Laurino M, Garbella E, Menicucci D, Neri B, Gemignani A. How Breath-Control Can Change Your Life: A Systematic Review on Psycho-Physiological Correlates of Slow Breathing. Front Hum Neurosci. 2018 Sep 7;12:353. doi: 10.3389/fnhum.2018.00353. PMID: 30245619; PMCID: PMC6137615. Migliaccio GM, Russo L, Maric M, Padulo J. Sports Performance and Breathing Rate: What Is the Connection? A Narrative Review on Breathing Strategies. Sports (Basel). 2023 May 10;11(5):103. doi: 10.3390/sports11050103. PMID: 37234059; PMCID: PMC10224217. Harbour E, Stöggl T, Schwameder H, Finkenzeller T. Breath Tools: A Synthesis of Evidence-Based Breathing Strategies to Enhance Human Running. Front Physiol. 2022 Mar 17;13:813243. doi: 10.3389/fphys.2022.813243. PMID: 35370762; PMCID: PMC8967998. Sikora, M., Mikołajczyk, R., Łakomy, O. et al. Influence of the breathing pattern on the pulmonary function of endurance-trained athletes. Sci Rep 14, 1113 (2024). https://doi.org/10.1038/s41598-024-51758-5 Harari D, Redlich M, Miri S, Hamud T, Gross M. The effect of mouth breathing versus nasal breathing on dentofacial and craniofacial development in orthodontic patients. Laryngoscope. 2010 Oct;120(10):2089-93. doi: 10.1002/lary.20991. PMID: 20824738. Lee YC, Lu CT, Cheng WN, Li HY. The Impact of Mouth-Taping in Mouth-Breathers with Mild Obstructive Sleep Apnea: A Preliminary Study. Healthcare (Basel). 2022 Sep 13;10(9):1755. doi: 10.3390/healthcare10091755. PMID: 36141367; PMCID: PMC9498537. M Mapelli, E Salvioni, I Mattavelli, G Grilli, G Zerboni, A Nava, N Capra, M Biroli, M Dell'asta, A De Paola, L Terzolini, N Mani, S Turri, J Campodonico, P Agostoni, Nasal vs. oral BREATHing WIn Strategies in healthy individuals during cardiorespiratory exercise testing (BreathWISE), European Journal of Preventive Cardiology, Volume 32, Issue Supplement_1, May 2025, zwaf236.175, Lin L, Zhao T, Qin D, Hua F, He H. The impact of mouth breathing on dentofacial development: A concise review. Front Public Health. 2022 Sep 8;10:929165. doi: 10.3389/fpubh.2022.929165. PMID: 36159237; PMCID: PMC9498581. Masutomi, Y., Goto, T. & Ichikawa, T. Mouth breathing reduces oral function in adolescence. Sci Rep 14, 3810 (2024). https://doi.org/10.1038/s41598-024-54328-x See omnystudio.com/listener for privacy information.

11-25
31:53

Suiker: maakt één piek je ouder?

Moet je meteen paniek hebben bij 1 suikerpiek? En wat is nu te veel suiker? Tom test zijn suikergrenzen in de praktijk, Alexander duikt in de wetenschap achter glucosepieken, stress, slaap en zoetstoffen. Kortom: eindelijk helderheid in een van de meest gehypete gezondheidsthema’s van dit moment.In deze aflevering:🍬 Hoe slecht is een glucosepiek nu écht?😴 Kunnen stress en slechte slaap je bloedsuiker verpesten?🍏 Is suiker gewoon suiker, maakt een appel net zo’n piek als een reep chocola?🍭 Zijn kunstmatige zoetstoffen beter voor je gezondheid dan suiker?🥤 En: werkt appelazijn of een handje amandelen écht tegen glucosepieken?Tom test, Alexander fileert de feiten, zodat jij voortaan slim met suiker omgaat (zonder paniek of pieken).  🎧 Geproduceerd door Tonny Media👉 Volg ons op Instagram, TikTok en YouTube🥼Alle onderzoeken die in deze aflevering worden besproken vind je hier: Wu Y, Ehlert B, Metwally AA, Perelman D, Park H, Brooks AW, Abbasi F, Michael B, Celli A, Bejikian C, Ayhan E, Lu Y, Lancaster SM, Hornburg D, Ramirez L, Bogumil D, Pollock S, Wong F, Bradley D, Gutjahr G, Rangan ES, Wang T, McGuire L, Venkat Rangan P, Ræder H, Shipony Z, Lipson D, McLaughlin T, Snyder MP. Individual variations in glycemic responses to carbohydrates and underlying metabolic physiology. Nat Med. 2025 Jul;31(7):2232-2243. doi: 10.1038/s41591-025-03719-2. Epub 2025 Jun 4. PMID: 40467897; PMCID: PMC12283382. Song J, Oh TJ, Song Y. Individual Postprandial Glycemic Responses to Meal Types by Different Carbohydrate Levels and Their Associations with Glycemic Variability Using Continuous Glucose Monitoring. Nutrients. 2023 Aug 13;15(16):3571. doi: 10.3390/nu15163571. PMID: 37630761; PMCID: PMC10459284.Giuntini EB, Sardá FAH, de Menezes EW. The Effects of Soluble Dietary Fibers on Glycemic Response: An Overview and Futures Perspectives. Foods. 2022 Dec 6;11(23):3934. doi: 10.3390/foods11233934. PMID: 36496742; PMCID: PMC9736284. Richter EA, Bilan PJ, Klip A. A comprehensive view of muscle glucose uptake: regulation by insulin, contractile activity, and exercise. Physiol Rev. 2025 Jul 1;105(3):1867-1945. doi: 10.1152/physrev.00033.2024. Epub 2025 Apr 2. PMID: 40173020. Hulett NA, Scalzo RL, Reusch JEB. Glucose Uptake by Skeletal Muscle within the Contexts of Type 2 Diabetes and Exercise: An Integrated Approach. Nutrients. 2022 Feb 3;14(3):647. doi: 10.3390/nu14030647. PMID: 35277006; PMCID: PMC8839578. Klimontov VV, Saik OV, Korbut AI. Glucose Variability: How Does It Work? Int J Mol Sci. 2021 Jul 21;22(15):7783. doi: 10.3390/ijms22157783. PMID: 34360550; PMCID: PMC8346105. Belli M, Bellia A, Sergi D, Barone L, Lauro D, Barillà F. Glucose variability: a new risk factor for cardiovascular disease. Acta Diabetol. 2023 Oct;60(10):1291-1299. doi: 10.1007/s00592-023-02097-w. Epub 2023 Jun 21. PMID: 37341768; PMCID: PMC10442283.Reynolds AN, Akerman AP, Mann J. Dietary fibre and whole grains in diabetes management: Systematic review and meta-analyses. PLoS Med. 2020 Mar 6;17(3):e1003053. doi: 10.1371/journal.pmed.1003053. PMID: 32142510; PMCID: PMC7059907.Weickert MO, Pfeiffer AFH. Impact of Dietary Fiber Consumption on Insulin Resistance and the Prevention of Type 2 Diabetes. J Nutr. 2018 Jan 1;148(1):7-12. doi: 10.1093/jn/nxx008. PMID: 29378044.Gulliford MC, Bicknell EJ, Scarpello JH. Differential effect of protein and fat ingestion on blood glucose responses to high- and low-glycemic-index carbohydrates in noninsulin-dependent diabetic subjects. Am J Clin Nutr. 1989 Oct;50(4):773-7. doi: 10.1093/ajcn/50.4.773. PMID: 2679037.Basturk B, Koc Ozerson Z, Yuksel A. Evaluation of the Effect of Macronutrients Combination on Blood Sugar Levels in Healthy Individuals. Iran J Public Health. 2021 Feb;50(2):280-287. doi: 10.18502/ijph.v50i2.5340. PMID: 33747991; PMCID: PMC7956086.Tiwari R, Tam DNH, Shah J, Moriyama M, Varney J, Huy NT. Effects of sleep intervention on glucose control: A narrative review of clinical evidence. Prim Care Diabetes. 2021 Aug;15(4):635-641. doi: 10.1016/j.pcd.2021.04.003. Epub 2021 Apr 10. PMID: 33849816.St-Onge MP, Cherta-Murillo A, Darimont C, Mantantzis K, Martin FP, Owen L. The interrelationship between sleep, diet, and glucose metabolism. Sleep Med Rev. 2023 Jun;69:101788. doi: 10.1016/j.smrv.2023.101788. Epub 2023 Apr 28. PMID: 37156196; PMCID: PMC10247426.Eyth E, Zubair M, Naik R. Hemoglobin A1C. 2025 Jun 2. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 31747223.Boniol M, Dragomir M, Autier P, Boyle P. Physical activity and change in fasting glucose and HbA1c: a quantitative meta-analysis of randomized trials. Acta Diabetol. 2017 Nov;54(11):983-991. doi: 10.1007/s00592-017-1037-3. Epub 2017 Aug 24. PMID: 28840356.Ghusn W, Naik R, Yibirin M. The Impact of Artificial Sweeteners on Human Health and Cancer Association: A Comprehensive Clinical Review. Cureus. 2023 Dec 29;15(12):e51299. doi: 10.7759/cureus.51299. PMID: 38288206; PMCID: PMC10822749.Qin L, Yu Y, Yu R. Artificially sweetened beverages do not influence metabolic risk factors: a systematic review and meta-analysis. Front Nutr. 2025 May 9;12:1482719. doi: 10.3389/fnut.2025.1482719. PMID: 40416387; PMCID: PMC12098100.McGlynn ND, Khan TA, Wang L, Zhang R, Chiavaroli L, Au-Yeung F, Lee JJ, Noronha JC, Comelli EM, Blanco Mejia S, Ahmed A, Malik VS, Hill JO, Leiter LA, Agarwal A, Jeppesen PB, Rahelic D, Kahleová H, Salas-Salvadó J, Kendall CWC, Sievenpiper JL. Association of Low- and No-Calorie Sweetened Beverages as a Replacement for Sugar-Sweetened Beverages With Body Weight and Cardiometabolic Risk: A Systematic Review and Meta-analysis. JAMA Netw Open. 2022 Mar 1;5(3):e222092. doi: 10.1001/jamanetworkopen.2022.2092. PMID: 35285920; PMCID: PMC9907347.Miller PE, Perez V. Low-calorie sweeteners and body weight and composition: a meta-analysis of randomized controlled trials and prospective cohort studies. Am J Clin Nutr. 2014 Sep;100(3):765-77. doi: 10.3945/ajcn.113.082826. Epub 2014 Jun 18. PMID: 24944060; PMCID: PMC4135487.Pang MD, Kjølbæk L, Bastings JJAJ, Andersen SSH, Umanets A, Sost MM, Navas-Carretero S, Reppas K, Finlayson G, Hodgkins CE, Del Álamo M, Lam T, Moshoyiannis H, Feskens EJM, Adam TCM, Goossens GH, Halford JCG, Harrold JA, Manios Y, Martinez JA, Blaak EE, Raben A. Effect of sweeteners and sweetness enhancers on weight management and gut microbiota composition in individuals with overweight or obesity: the SWEET study. Nat Metab. 2025 Oct;7(10):2083-2098. doi: 10.1038/s42255-025-01381-z. Epub 2025 Oct 7. PMID: 41057614; PMCID: PMC12552123.Chia CW, Egan JM, Ferrucci L. Age-Related Changes in Glucose Metabolism, Hyperglycemia, and Cardiovascular Risk. Circ Res. 2018 Sep 14;123(7):886-904. doi: 10.1161/CIRCRESAHA.118.312806. PMID: 30355075; PMCID: PMC6205735.Dhillon J, Lee JY, Mattes RD. The cephalic phase insulin response to nutritive and low-calorie sweeteners in solid and beverage form. Physiol Behav. 2017 Nov 1;181:100-109. doi: 10.1016/j.physbeh.2017.09.009. Epub 2017 Sep 9. PMID: 28899680; PMCID: PMC5634742.Wen J, Wu Q, Li S, Liu Y, Wen D. Effects of Non-Nutritive Sweeteners on Weight Loss and Maintenance, Metabolic Improvement, and Appetite Regulation in Weight Management Programs: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutr Rev. 2025 Jul 16:nuaf094. doi: 10.1093/nutrit/nuaf094. Epub ahead of print. PMID: 40668953.Jarvis PRE, Cardin JL, Nisevich-Bede PM, McCarter JP. Continuous glucose monitoring in a healthy population: understanding the post-prandial glycemic response in individuals without diabetes mellitus. Metabolism. 2023 Sep;146:155640. doi: 10.1016/j.metabol.2023.155640. Epub 2023 Jun 24. PMID: 37356796.Flockhart M, Larsen FJ. Continuous Glucose Monitoring in Endurance Athletes: Interpretation and Relevance of Measurements for Improving Performance and Health. Sports Med. 2024 Feb;54(2):247-255. doi: 10.1007/s40279-023-01910-4. Epub 2023 Sep 2. PMID: 37658967; PMCID: PMC10933193. See omnystudio.com/listener for privacy information.

11-18
28:07

Intermittent fasting: wondermiddel of gewoon honger lijden?

Is vasten dé sleutel tot vetverlies, focus en een langer leven, of vooral een excuus om het ontbijt over te slaan? Tom test het in de praktijk (met een knorrende maag), terwijl Alexander uitzoekt wat de wetenschap écht zegt over vasten en gezondheid.In deze aflevering:🥐 Val je echt sneller af door intermittent fasting?🧠 Helpt vasten je beter focussen en minder moe te zijn?💪 Is sporten op een lege maag slim of breek je dan juist spieren af?⏳ En: verlengt vasten echt je levensduur?Tom hongert, Alexander checkt de feiten. Alles om te ontdekken: is het vasten waard? 🎧 Geproduceerd door Tonny Media👉 Volg ons op Instagram, TikTok en YouTube🥼Alle onderzoeken die in deze aflevering worden besproken vind je hier:See omnystudio.com/listener for privacy information.

11-11
28:31

Helpen collageen poeders en LED-maskers écht voor een strakke huid?

Helpen collageen poeders en LED-maskers écht voor een strakke huid? Iedereen wil een strakkere huid, maar wat werkt nu écht tegen huidveroudering? Tom test microneedling, oftewel heel veel kleine naaldjes in z’n gezicht en Alexander duikt in de wetenschap achter de populairste huidclaims.Van LED-maskers tot collageen-supplementen: wat is bewezen effectief, en wat vooral dure onzin?In deze aflevering:  Infraroodlicht en LED: zorgt het echt voor een strakkere huid?  Collageen supplementen, helpt het van binnenuit?  Microneedling: marteling of miraculeus?  En: krijg je van stress echt sneller rimpels? Tom voelt het aan den lijve, Alexander checkt de wetenschap. Alles om te ontdekken wat je huid écht jong houdt, zonder filter.Het antwoord hoor je in aflevering 5 van Lang Zal Je Leven.🎧Geproduceerd door Tonny Media👉Volg ons op Instagram, TikTok en YouTube🥼Alle onderzoeken die in deze aflevering worden besproken vind je hier:     Myung SK, Park Y. Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Am J Med. 2025 Sep;138(9):1264-1277. doi: 10.1016/j.amjmed.2025.04.034. Epub 2025 May 3. PMID: 40324552. Pu SY, Huang YL, Pu CM, Kang YN, Hoang KD, Chen KH, Chen C. Effects of Oral Collagen for Skin Anti-Aging: A Systematic Review and Meta-Analysis. Nutrients. 2023 Apr 26;15(9):2080. doi: 10.3390/nu15092080. PMID: 37432180; PMCID: PMC10180699. Jaiswal S, Jawade S. Microneedling in Dermatology: A Comprehensive Review of Applications, Techniques, and Outcomes. Cureus. 2024 Sep 23;16(9):e70033. doi: 10.7759/cureus.70033. PMID: 39449889; PMCID: PMC11499218. Oizumi, R., Kaku, H., Higuchi, N., Kawabata, F., & Sugasawa, K. (2024). The Potential of Exercise on Lifestyle and Skin Function. International Journal of Environmental Research and Public Health, 21(6), Article 79338. https://pmc.ncbi.nlm.nih.gov/articles/PMC10979338/ Nishikori, S., Tominaga, M., Yuki, T., Yamashita, M., Ohta, Y., & Morita, A. (2023). Resistance training rejuvenates aging skin by reducing circulating inflammatory factors and enhancing dermal extracellular matrix. Scientific Reports, 13, Article 37207. https://doi.org/10.1038/s41598-023-37207-9 Li, F., Li, S., & Xie, H. (2025). The Effects of Physical Activity on Skin Health: A Narrative Review. Clinical, Cosmetic and Investigational Dermatology, 15, 2189–2200. https://www.dovepress.com/the-effects-of-physical-activity-on-skin-health-a-narrative-review-peer-reviewed-fulltext-article-CCID Khatri, M., Naughton, R., Ortega-Perez, R., et al. (2021). The effects of collagen peptide supplementation on body composition, collagen synthesis, and recovery: A systematic review of randomized controlled trials. Nutrients, 13(9), 3229. https://pmc.ncbi.nlm.nih.gov/articles/PMC8521576/ Sheppard, R., Sladden, M., & Sullivan, T. (2024). Increased physical activity promotes skin clearance, improves cardiovascular and psychological health, and increases functional capacity in patients with psoriasis. Skin Health and Disease, 4(1), e426. https://onlinelibrary.wiley.com/doi/full/10.1002/ski2.426 Kastella, F., Riyahi, P., Sato, Y., & Nedachi, T. (2024). Potential mechanisms of exercise in maintaining skin integrity: A narrative review. World Academy of Sciences Journal, 6(3), 27-39. https://www.spandidos-publications.com/10.3892/wasj.2024.235 Crane, J. D., MacNeil, L. G., Lally, J. S., et al. (2015). Exercise stimulates IL-15 production and preserves mitochondrial function in aging skin. Aging Cell, 14(2), 207-215. Ishiuchi-Sato, Y., & Nedachi, T. (2021). Muscle contraction and skin collagen synthesis: Reducing dermal CXCL10 to stimulate collagen in mouse models. Experimental Gerontology, 145, 111215. Medycyna Środowiskowa. (2024). Fit body, fit skin – the multifaceted effects of physical activity. Environmental Medicine, 27(1), 33-40. https://www.environmed.pl/pdf-178481-102011?filename=Sprawne+cialo_+sprawna.pdf Guan, L. L., Lim, H. W., & Mohammad, T. F. (2021). Sunscreens and Photoaging: A Review of Current Literature. American Journal of Clinical Dermatology, 22(5), 813-828. https://pmc.ncbi.nlm.nih.gov/articles/PMC8361399/ Hughes, M. C., Williams, G. M., & Baker, P. (2013). Sunscreen and prevention of skin aging: A randomized trial. Annals of Internal Medicine, 158(11), 781–790. Liu, L., & Han, R. (2023). Advances in Relationship Between Alcohol Consumption and Skin Diseases. Journal of Clinical and Aesthetic Dermatology, 16(12), 45-51. https://pmc.ncbi.nlm.nih.gov/articles/PMC10759914/ Patel, S., & Prasad, S. (2024). A Decade of Evidence Linking Sleep Quality to Dermatologic Outcomes: An Integrative Review. American Journal of Dermatology, 8(6), 15-32. https://www.arcjournals.org/pdfs/ajd/v8-i6/2.pdf Chen, Y., & Lyga, J. (2023). Brain–Skin Connection: Stress, Inflammation and Skin Aging. Dermato-Endocrinology, 15(1), e2181133. See omnystudio.com/listener for privacy information.

11-04
30:11

Zweet je jezelf oud? Dit kan de sauna doen voor dementie

Regelmatig in de sauna? Dan leef je misschien wel langer. In deze aflevering duiken Tom en Alexander in het zweet om te ontdekken of sauneren de kans op dementie én hartproblemen echt verkleint.Tom test vier dagen lang verschillende sauna’s, van Finse hitte tot infrarood licht, terwijl dokter Alexander de claims ontleedt: 🔥 Sauna (infrarood) helpt met spierherstel💧 Afvallen en detoxen door zweten🧠 Sauna verkleint de kans op dementie en Alzheimer❤️ Sauna is goed voor je hartgezondheid Het antwoord hoor je in aflevering 4 van Lang Zal Je Leven. 🎧 Geproduceerd door Tonny Media👉 Volg ons op Instagram, TikTok en YouTube🥼 Alle onderzoeken die in deze aflevering worden besproken vind je hier: Laukkanen T, Kunutsor SK, Zaccardi F, Lee E, Willeit P, Khan H, Laukkanen JA. Acute effects of sauna bathing on cardiovascular function. J Hum Hypertens. 2018 Feb;32(2):129-138. doi: 10.1038/s41371-017-0008-z. Epub 2017 Dec 21. PMID: 29269746. Laukkanen T, Khan H, Zaccardi F, Laukkanen JA. Association between sauna bathing and fatal cardiovascular and all-cause mortality events. JAMA Intern Med. 2015 Apr;175(4):542-8. doi: 10.1001/jamainternmed.2014.8187. PMID: 25705824. Laukkanen T, Kunutsor S, Kauhanen J, Laukkanen JA. Sauna bathing is inversely associated with dementia and Alzheimer's disease in middle-aged Finnish men. Age Ageing. 2017 Mar 1;46(2):245-249. doi: 10.1093/ageing/afw212. PMID: 27932366. Laukkanen T, Kunutsor SK, Khan H, Willeit P, Zaccardi F, Laukkanen JA. Sauna bathing is associated with reduced cardiovascular mortality and improves risk prediction in men and women: a prospective cohort study. BMC Med. 2018 Nov 29;16(1):219. doi: 10.1186/s12916-018-1198-0. PMID: 30486813; PMCID: PMC6262976. Kunutsor SK, Khan H, Zaccardi F, Laukkanen T, Willeit P, Laukkanen JA. Sauna bathing reduces the risk of stroke in Finnish men and women: A prospective cohort study. Neurology. 2018 May 29;90(22):e1937-e1944. doi: 10.1212/WNL.0000000000005606. Epub 2018 May 2. PMID: 29720543. Imamura, M, Biro, S, Kihara, T. et al. Repeated thermal therapy improves impaired vascular endothelial function in patients with coronary risk factors. JACC. 2001 Oct, 38 (4) 1083–1088. https://doi.org/10.1016/S0735-1097(01)01467-X Lee E, Laukkanen T, Kunutsor SK, Khan H, Willeit P, Zaccardi F, Laukkanen JA. Sauna exposure leads to improved arterial compliance: Findings from a non-randomised experimental study. Eur J Prev Cardiol. 2018 Jan;25(2):130-138. doi: 10.1177/2047487317737629. Epub 2017 Oct 19. PMID: 29048215. Kunutsor, S. K., Khan, H., Laukkanen, T., & Laukkanen, J. A. (2017). Joint associations of sauna bathing and cardiorespiratory fitness on cardiovascular and all-cause mortality risk: a long-term prospective cohort study. Annals of Medicine, 50(2), 139–146. https://doi.org/10.1080/07853890.2017.1387927 Knekt P, Järvinen R, Rissanen H, Heliövaara M, Aromaa A. Does sauna bathing protect against dementia? Prev Med Rep. 2020 Oct 2;20:101221. doi: 10.1016/j.pmedr.2020.101221. PMID: 33088678; PMCID: PMC7560162. Kunutsor SK, Jae SY, Laukkanen JA. Frequent sauna bathing offsets the increased risk of death due to low socioeconomic status: A prospective cohort study of middle-aged and older men. Exp Gerontol. 2022 Oct 1;167:111906. doi: 10.1016/j.exger.2022.111906. Epub 2022 Jul 28. PMID: 35908583. Scoon GS, Hopkins WG, Mayhew S, Cotter JD. Effect of post-exercise sauna bathing on the endurance performance of competitive male runners. J Sci Med Sport. 2007 Aug;10(4):259-62. doi: 10.1016/j.jsams.2006.06.009. Epub 2006 Jul 31. PMID: 16877041. Ahokas EK, Ihalainen JK, Hanstock HG, Savolainen E, Kyröläinen H. A post-exercise infrared sauna session improves recovery of neuromuscular performance and muscle soreness after resistance exercise training. Biol Sport. 2023 Jul;40(3):681-689. doi: 10.5114/biolsport.2023.119289. Epub 2022 Sep 15. PMID: 37398966; PMCID: PMC10286597. Garrett AT, Goosens NG, Rehrer NJ, Patterson MJ, Harrison J, Sammut I, Cotter JD. Short-term heat acclimation is effective and may be enhanced rather than impaired by dehydration. Am J Hum Biol. 2014 May-Jun;26(3):311-20. doi: 10.1002/ajhb.22509. Epub 2014 Jan 28. PMID: 24469986. Pilch W, Pokora I, Szyguła Z, Pałka T, Pilch P, Cisoń T, Malik L, Wiecha S. Effect of a single finnish sauna session on white blood cell profile and cortisol levels in athletes and non-athletes. J Hum Kinet. 2013 Dec 31;39:127-35. doi: 10.2478/hukin-2013-0075. PMID: 24511348; PMCID: PMC3916915. Kissling LS, Akerman AP, Campbell HA, Prout JR, Gibbons TD, Thomas KN, Cotter JD. A crossover control study of three methods of heat acclimation on the magnitude and kinetics of adaptation. Exp Physiol. 2022 Apr;107(4):337-349. doi: 10.1113/EP089993. Epub 2022 Mar 16. PMID: 34957632. Hedley AM, Climstein M, Hansen R. The effects of acute heat exposure on muscular strength, muscular endurance, and muscular power in the euhydrated athlete. J Strength Cond Res. 2002 Aug;16(3):353-8. PMID: 12173948. Kirby NV, Lucas SJE, Cable TG, Armstrong OJ, Weaver SR, Lucas RAI. Sex differences in adaptation to intermittent post-exercise sauna bathing in trained middle-distance runners. Sports Med Open. 2021 Jul 23;7(1):51. doi: 10.1186/s40798-021-00342-6. PMID: 34297227; PMCID: PMC8302716. Hayasaka S, Nakamura Y, Kajii E, Ide M, Shibata Y, Noda T, Murata C, Nagata K, Ojima T. Effects of charcoal kiln saunas (Jjimjilbang) on psychological states. Complement Ther Clin Pract. 2008 May;14(2):143-8. doi: 10.1016/j.ctcp.2007.12.004. Epub 2008 Mar 4. PMID: 18396259. Naumann J, Grebe J, Kaifel S, Weinert T, Sadaghiani C, Huber R. Effects of hyperthermic baths on depression, sleep and heart rate variability in patients with depressive disorder: a randomized clinical pilot trial. BMC Complement Altern Med. 2017 Mar 28;17(1):172. doi: 10.1186/s12906-017-1676-5. PMID: 28351399; PMCID: PMC5371197. Laukkanen T, Laukkanen JA, Kunutsor SK. Sauna Bathing and Risk of Psychotic Disorders: A Prospective Cohort Study. Med Princ Pract. 2018;27(6):562-569. doi: 10.1159/000493392. Epub 2018 Sep 2. PMID: 30173212; PMCID: PMC6422146. https://journals.sagepub.com/doi/10.1177/089198879600900203 Hussain JN, Greaves RF, Cohen MM. A hot topic for health: Results of the Global Sauna Survey. Complement Ther Med. 2019 Jun;44:223-234. doi: 10.1016/j.ctim.2019.03.012. Epub 2019 Apr 24. PMID: 31126560. See omnystudio.com/listener for privacy information.

10-28
21:44

Hoeveel koffie is te veel?

Iedereen drinkt het, maar bijna niemand weet: hoeveel koppen koffie zijn nog gezond?Tom test het op de harde manier, van een overdosis aan koffie naar cold turkey helemaal geen koffie en dokter Alexander legt uit wat de wetenschap zegt over de ideale dosis. In deze aflevering bespreken ze: Helpt koffie écht tegen vermoeidheid? Hoeveel koppen koffie zijn goed voor je, en waarom is de timing belangrijk? Is koffie goed voor afvallen en je hartgezondheid? Droogt het je uit, en klopt het dat het je stresshormoon omhoog jaagt? Tom test het in de praktijk, Alexander checkt de wetenschap. 🗣️ Waar zoek jij naar steun? Als grootste online therapieplatform ter wereld biedt Betterhelp toegang tot deskundige therapeuten. Luisteraars van deze podcast krijgen 10% korting op de eerste maand via www.betterhelp.com/langzaljeleven  🎧 Geproduceerd door Tonny Media👉 Volg ons op Instagram, TikTok en YouTubeOnderzoeken die Alexander heeft gebruik voor deze aflevering:  Blanchard J, Sawers SJ. The absolute bioavailability of caffeine in man. Eur J Clin Pharmacol. 1983;24(1):93-98. doi:10.1007/bf00613933 Huang ZL, Qu WM, Eguchi N, et al. Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine. Nat Neurosci. 2005;8(7):858-859. doi:10.1038/nn1491 Reichert CF, Deboer T, Landolt HP. Adenosine, caffeine, and sleep-wake regulation: state of the science and perspectives. J Sleep Res. 2022;31(4):e13597. doi:10.1111/jsr.13597 Alasmari F. Caffeine induces neurobehavioral effects through modulating neurotransmitters. Saudi Pharm J. 2020;28(4):445-451. doi:10.1016/j.jsps.2020.02.005 Tian DD, Natesan S, White JR , Jr, Paine MF. Effects of common CYP1A2 genotypes and other key factors on intraindividual variation in the caffeine metabolic ratio: An exploratory analysis. Clin Transl Sci. 2019;12(1):39-46. doi:10.1111/cts.12598 Faber MS, Jetter A, Fuhr U. Assessment of CYP1A2 activity in clinical practice: why, how, and when? Basic Clin Pharmacol Toxicol. 2005;97(3):125-134. doi:10.1111/j.1742-7843.2005.pto_973160.x Low JJL, Tan BJW, Yi LX, Zhou ZD, Tan EK. Genetic susceptibility to caffeine intake and metabolism: a systematic review. J Transl Med. 2024;22(1):961. doi:10.1186/s12967-024-05737-z Matthaei J, Tzvetkov MV, Strube J, et al. Heritability of caffeine metabolism: Environmental effects masking genetic effects on CYP1A2 activity but not on NAT2. Clin Pharmacol Ther. 2016;100(6):606-616. doi:10.1002/cpt.444 Parsons WD, Neims AH. Effect of smoking on caffeine clearance. Clin Pharmacol Ther. 1978;24(1):40-45. doi:10.1002/cpt197824140 Gunes A, Ozbey G, Vural EH, et al. Influence of genetic polymorphisms, smoking, gender and age on CYP1A2 activity in a Turkish population. Pharmacogenomics. 2009;10(5):769-778. doi:10.2217/pgs.09.22 Kall MA, Clausen J. Dietary effect on mixed function P450 1A2 activity assayed by estimation of caffeine metabolism in man. Hum Exp Toxicol. 1995;14(10):801-807. doi:10.1177/096032719501401004 Vistisen K, Poulsen HE, Loft S. Foreign compound metabolism capacity in man measured from metabolites of dietary caffeine. Carcinogenesis. 1992;13(9):1561-1568. doi:10.1093/carcin/13.9.1561 Abernethy DR, Todd EL. Impairment of caffeine clearance by chronic use of low-dose oestrogen-containing oral contraceptives. Eur J Clin Pharmacol. 1985;28(4):425-428. doi:10.1007/bf00544361 Gunes A, Dahl ML. Variation in CYP1A2 activity and its clinical implications: influence of environmental factors and genetic polymorphisms. Pharmacogenomics. 2008;9(5):625-637. doi:10.2217/14622416.9.5.625 Lane JD, Steege JF, Rupp SL, Kuhn CM. Menstrual cycle effects on caffeine elimination in the human female. Eur J Clin Pharmacol. 1992;43(5):543-546. doi:10.1007/bf02285099 Tracy TS, Venkataramanan R, Glover DD, Caritis SN, National Institute for Child Health and Human Development Network of Maternal-Fetal-Medicine Units. Temporal changes in drug metabolism (CYP1A2, CYP2D6 and CYP3A Activity) during pregnancy. Am J Obstet Gynecol. 2005;192(2):633-639. doi:10.1016/j.ajog.2004.08.030 Djordjevic N, Ghotbi R, Bertilsson L, Jankovic S, Aklillu E. Induction of CYP1A2 by heavy coffee consumption in Serbs and Swedes. Eur J Clin Pharmacol. 2008;64(4):381-385. doi:10.1007/s00228-007-0438-6 Fulgoni VL 3rd, Keast DR, Lieberman HR. Trends in intake and sources of caffeine in the diets of US adults: 2001-2010. Am J Clin Nutr. 2015;101(5):1081-1087. doi:10.3945/ajcn.113.080077 Lorenzo Calvo J, Fei X, Domínguez R, Pareja-Galeano H. Caffeine and cognitive functions in sports: A systematic review and meta-analysis. Nutrients. 2021;13(3):868. doi:10.3390/nu13030868 McLellan TM, Caldwell JA, Lieberman HR. A review of caffeine’s effects on cognitive, physical and occupational performance. Neurosci Biobehav Rev. 2016;71:294-312. doi:10.1016/j.neubiorev.2016.09.001 Wilhelmus MM, Hay JL, Zuiker RG, et al. Effects of a single, oral 60 mg caffeine dose on attention in healthy adult subjects. J Psychopharmacol. 2017;31(2):222-232. doi:10.1177/0269881116668593 Liu C, Wang L, Zhang C, et al. Caffeine intake and anxiety: a meta-analysis. Front Psychol. 2024;15:1270246. doi:10.3389/fpsyg.2024.1270246 Březinová V. Effect of caffeine on sleep: EEG study in late middle age people. Br J Clin Pharmacol. 1974;1(3):203-208. doi:10.1111/j.1365-2125.1974.tb00237.x Gardiner CL, Weakley J, Burke LM, et al. Dose and timing effects of caffeine on subsequent sleep: A randomised clinical crossover trial. Sleep. Published online October 8, 2024. doi:10.1093/sleep/zsae230 Quiquempoix M, Drogou C, Erblang M, et al. Relationship between habitual caffeine consumption, attentional performance, and individual alpha frequency during total sleep deprivation. Int J Environ Res Public Health. 2023;20(6). doi:10.3390/ijerph20064971 Glaister M, Gissane C. Caffeine and physiological responses to submaximal exercise: A meta-analysis. Int J Sports Physiol Perform. 2018;13(4):402-411. doi:10.1123/ijspp.2017-0312 Doherty M, Smith PM. Effects of caffeine ingestion on rating of perceived exertion during and after exercise: a meta-analysis. Scand J Med Sci Sports. 2005;15(2):69-78. doi:10.1111/j.1600-0838.2005.00445.x Desbrow B, Biddulph C, Devlin B, Grant GD, Anoopkumar-Dukie S, Leveritt MD. The effects of different doses of caffeine on endurance cycling time trial performance. J Sports Sci. 2012;30(2):115-120. doi:10.1080/02640414.2011.632431 Southward K, Rutherfurd-Markwick KJ, Ali A. Correction to: The effect of acute caffeine ingestion on endurance performance: A systematic review and meta-analysis. Sports Med. 2018;48(10):2425-2441. doi:10.1007/s40279-018-0967-4 Guest NS, VanDusseldorp TA, Nelson MT, et al. International society of sports nutrition position stand: caffeine and exercise performance. J Int Soc Sports Nutr. 2021;18(1):1. doi:10.1186/s12970-020-00383-4 Wang Z, Qiu B, Gao J, Del Coso J. Effects of caffeine intake on endurance running performance and time to exhaustion: A systematic review and meta-analysis. Nutrients. 2022;15(1):148. doi:10.3390/nu15010148 Carvalho A, Marticorena FM, Grecco BH, Barreto G, Saunders B. Can I have my coffee and drink it? A systematic review and meta-analysis to determine whether habitual caffeine consumption affects the ergogenic effect of caffeine. Sports Med. 2022;52(9):2209-2220. doi:10.1007/s40279-022-01685-0 Lara B, Ruiz-Moreno C, Salinero JJ, Del Coso J. Time course of tolerance to the performance benefits of caffeine. PLoS One. 2019;14(1):e0210275. doi:10.1371/journal.pone.0210275 Pickering C, Kiely J. What should we do about habitual caffeine use in athletes? Sports Med. 2019;49(6):833-842. doi:10.1007/s40279-018-0980-7 Warren GL, Park ND, Maresca RD, McKibans KI, Millard-Stafford ML. Effect of caffeine ingestion on muscular strength and endurance: a meta-analysis. Med Sci Sports Exerc. 2010;42(7):1375-1387. doi:10.1249/MSS.0b013e3181cabbd8 Grgic J, Trexler ET, Lazinica B, Pedisic Z. Effects of caffeine intake on muscle strength and power: a systematic review and meta-analysis. J Int Soc Sports Nutr. 2018;15:11. doi:10.1186/s12970-018-0216-0 Grgic J, Grgic I, Pickering C, Schoenfeld BJ, Bishop DJ, Pedisic Z. Wake up and smell the coffee: caffeine supplementation and exercise performance-an umbrella review of 21 published meta-analyses. Br J Sports Med. 2020;54(11):681-688. doi:10.1136/bjsports-2018-100278 Ferreira TT, da Silva JVF, Bueno NB. Effects of caffeine supplementation on muscle endurance, maximum strength, and perceived exertion in adults submitted to strength training: a systematic review and meta-analyses. Crit Rev Food Sci Nutr. 2021;61(15):2587-2600. doi:10.1080/10408398.2020.1781051 Lopes-Silva JP, Choo HC, Franchini E, Abbiss CR. Isolated ingestion of caffeine and sodium bicarbonate on repeated sprint performance: A systematic review and meta-analysis. J Sci Med Sport. 2019;22(8):962-972. doi:10.1016/j.jsams.2019.03.007 Collegiate and Professional Sports Dietitians Association. Caffeine and Athletic Performance. National Collegiate Athletic Association; 2014. Koot P, Deurenberg P. Comparison of changes in energy expenditure and body temperatures after caffeine consumption. Ann Nutr Metab. 1995;39(3):135-142. doi:10.1159/000177854 Acheson KJ, Zahorska-Markiewicz B, Pittet P, Anantharaman K, Jéquier E. Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals. Am J Clin Nutr. 1980;33(5):989-997. doi:10.1093/ajcn/33.5.989 Acheson KJ, Gremaud G, Meirim I, et al. Metabolic effects of caffeine in humans: lipid oxidation or futile cycling? Am J Clin Nutr. 2004;79(1):40-46. doi:10.1093/ajcn/79.1.40 Gavrieli A, Karfopoulou E, Kardatou E, et al. Effect of different amounts of coffee on dietary intake and appetite of normal-weight and overweight/obese individuals. Obesity (Silver Spring). 2013;21(6):1127-1132. doi:10.1002/oby.20190 Tabrizi R, Saneei P, Lankarani KB, et al. The effects of caffeine intake on weight loss: a systematic review and dos-response meta-analysis of randomiz

10-21
26:58

Hoeveel eiwit heb je echt nodig?

Eiwitten: iedereen praat erover, waardoor ook Tom door de bomen het bos niet meer ziet. Daarom duiken dokter Alexander Rakic en proefkonijn Tom van der Kolk in deze aflevering van Lang Zal Je Leven in de wereld van eiwitten. Hoeveel heb je écht nodig, wanneer kun je het het best nemen, en helpt meer eiwit eten eigenlijk bij afvallen? Ze factchecken de populairste eiwitclaims: Moet je direct na het sporten eten vanwege het anabolic window? Hoeveel gram eiwit heb je nodig per kilo lichaamsgewicht? Helpt eiwit eten bij vetverlies? En is vegetarisch eten echt minder effectief dan vlees? Tom test het in de praktijk, Alexander checkt de wetenschap. 🗣️ Waar zoek jij naar steun? Als grootste online therapieplatform ter wereld biedt Betterhelp toegang tot deskundige therapeuten. Luisteraars van deze podcast krijgen 10% korting op de eerste maand via www.betterhelp.com/langzaljeleven  🎧 Geproduceerd door Tonny Media👉 Volg ons op Instagram, TikTok en YouTube🥼Alle onderzoeken die in deze aflevering worden besproken vind je hier: Morton RW, Murphy KT, McKellar SR, Schoenfeld BJ, Henselmans M, Helms E, Aragon AA, Devries MC, Banfield L, Krieger JW, Phillips SM. A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance training-induced gains in muscle mass and strength in healthy adults. Br J Sports Med. 2018 Mar;52(6):376-384. doi: 10.1136/bjsports-2017-097608. Epub 2017 Jul 11. Erratum in: Br J Sports Med. 2020 Oct;54(19):e7. doi: 10.1136/bjsports-2017-097608corr1. PMID: 28698222; PMCID: PMC5867436. Nunes EA, Colenso-Semple L, McKellar SR, Yau T, Ali MU, Fitzpatrick-Lewis D, Sherifali D, Gaudichon C, Tomé D, Atherton PJ, Robles MC, Naranjo-Modad S, Braun M, Landi F, Phillips SM. Systematic review and meta-analysis of protein intake to support muscle mass and function in healthy adults. J Cachexia Sarcopenia Muscle. 2022 Apr;13(2):795-810. doi: 10.1002/jcsm.12922. Epub 2022 Feb 20. PMID: 35187864; PMCID: PMC8978023. Tagawa R, Watanabe D, Ito K, Otsuyama T, Nakayama K, Sanbongi C, Miyachi M. Synergistic Effect of Increased Total Protein Intake and Strength Training on Muscle Strength: A Dose-Response Meta-analysis of Randomized Controlled Trials. Sports Med Open. 2022 Sep 4;8(1):110. doi: 10.1186/s40798-022-00508-w. PMID: 36057893; PMCID: PMC9441410. Santini MH, Erwig Leitão A, Mazzolani BC, Smaira FI, de Souza MSC, Santamaria A, Gualano B, Roschel H. Similar effects between animal-based and plant-based protein blend as complementary dietary protein on muscle adaptations to resistance training: findings from a randomized clinical trial. J Int Soc Sports Nutr. 2025 Dec;22(1):2568047. doi: 10.1080/15502783.2025.2568047. Epub 2025 Oct 8. PMID: 41059835; PMCID: PMC12509290. López-Moreno M, Rossi EV, López-Gil JF, Marrero-Fernández P, Roldán-Ruiz A, Bertotti G. Are Plant-Based Diets Detrimental to Muscular Strength? A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Sports Med Open. 2025 Jun 2;11(1):62. doi: 10.1186/s40798-025-00852-7. PMID: 40455307; PMCID: PMC12130401. Tagawa R, Watanabe D, Ito K, Ueda K, Nakayama K, Sanbongi C, Miyachi M. Dose-response relationship between protein intake and muscle mass increase: a systematic review and meta-analysis of randomized controlled trials. Nutr Rev. 2020 Nov 4;79(1):66–75. doi: 10.1093/nutrit/nuaa104. Epub ahead of print. PMID: 33300582; PMCID: PMC7727026. Trommelen J, van Lieshout GAA, Nyakayiru J, Holwerda AM, Smeets JSJ, Hendriks FK, van Kranenburg JMX, Zorenc AH, Senden JM, Goessens JPB, Gijsen AP, van Loon LJC. The anabolic response to protein ingestion during recovery from exercise has no upper limit in magnitude and duration in vivo in humans. Cell Rep Med. 2023 Dec 19;4(12):101324. doi: 10.1016/j.xcrm.2023.101324. PMID: 38118410; PMCID: PMC10772463. Zhao S, Zhang H, Xu Y, Li J, Du S, Ning Z. The effect of protein intake on athletic performance: a systematic review and meta-analysis. Front Nutr. 2024 Nov 6;11:1455728. doi: 10.3389/fnut.2024.1455728. PMID: 39628467; PMCID: PMC11613885. Hudson JL, Iii REB, Campbell WW. Protein Distribution and Muscle-Related Outcomes: Does the Evidence Support the Concept? Nutrients. 2020 May 16;12(5):1441. doi: 10.3390/nu12051441. PMID: 32429355; PMCID: PMC7285146. Møller G, Rikardt Andersen J, Ritz C, P Silvestre M, Navas-Carretero S, Jalo E, Christensen P, Simpson E, Taylor M, Martinez JA, Macdonald I, Swindell N, Mackintosh KA, Stratton G, Fogelholm M, Larsen TM, Poppitt SD, Dragsted LO, Raben A. Higher Protein Intake Is Not Associated with Decreased Kidney Function in Pre-Diabetic Older Adults Following a One-Year Intervention-A Preview Sub-Study. Nutrients. 2018 Jan 9;10(1):54. doi: 10.3390/nu10010054. PMID: 29315212; PMCID: PMC5793282. Cheng Y, Zheng G, Song Z, Zhang G, Rao X, Zeng T. Association between dietary protein intake and risk of chronic kidney disease: a systematic review and meta-analysis. Front Nutr. 2024 Jun 14;11:1408424. doi: 10.3389/fnut.2024.1408424. PMID: 38946781; PMCID: PMC11212527. Davies RW, Lynch AE, Kumar U, Jakeman PM. Characterisation of the Muscle Protein Synthetic Response to Resistance Exercise in Healthy Adults: A Systematic Review and Exploratory Meta-Analysis. Transl Sports Med. 2024 Apr 30;2024:3184356. doi: 10.1155/2024/3184356. PMID: 38716482; PMCID: PMC11074832. Kokura Y, Ueshima J, Saino Y, Maeda K. Enhanced protein intake on maintaining muscle mass, strength, and physical function in adults with overweight/obesity: A systematic review and meta-analysis. Clin Nutr ESPEN. 2024 Oct;63:417-426. doi: 10.1016/j.clnesp.2024.06.030. Epub 2024 Jun 24. PMID: 39002131. Guarneiri LL, Adams CG, Garcia-Jackson B, Koecher K, Wilcox ML, Maki KC. Effects of Varying Protein Amounts and Types on Diet-Induced Thermogenesis: A Systematic Review and Meta-Analysis. Adv Nutr. 2024 Dec;15(12):100332. doi: 10.1016/j.advnut.2024.100332. Epub 2024 Oct 31. PMID: 39486625; PMCID: PMC11625215. See omnystudio.com/listener for privacy information.

10-14
19:41

Helpt een ijsbad echt?

In deze aflevering van Lang Zal Je Leven onderzoeken dokter Alexander Rakic en proefkonijn Tom van der Kolk wat een ijsbad écht doet met je lichaam en brein. Helpt het bij spierherstel na het sporten, versterkt het je immuunsysteem, verhoogt het je dopamine, en kun je er zelfs van afvallen?  Of is het vooral een koude hype die lekker klinkt op TikTok? Tom test het zelf, Alexander checkt de wetenschap. 🗣️ Waar zoek jij naar steun? Als grootste online therapieplatform ter wereld biedt Betterhelp toegang tot deskundige therapeuten. Luisteraars van deze podcast krijgen 10% korting op de eerste maand via www.betterhelp.com/langzaljeleven  🎧 Geproduceerd door Tonny Media👉 Volg ons op Instagram, TikTok en YouTube🥼Alle onderzoeken die Alexander heeft gelezen voor deze aflevering vind je hier: Wang H, Wang L, Pan Y. Impact of different doses of cold water immersion (duration and temperature variations) on recovery from acute exercise-induced muscle damage: a network meta-analysis. Front Physiol. 2025 Feb 26;16:1525726. doi: 10.3389/fphys.2025.1525726. PMID: 40078372; PMCID: PMC11897523.Cain T, Brinsley J, Bennett H, Nelson M, Maher C, Singh B. Effects of cold-water immersion on health and wellbeing: A systematic review and meta-analysis. PLoS One. 2025 Jan 29;20(1):e0317615. doi: 10.1371/journal.pone.0317615. PMID: 39879231; PMCID: PMC11778651.Lee, H. J., Alirzayeva, H., Koyuncu, S., Rueber, A., Noormohammadi, A., & Vilchez, D. (2023). Cold temperature extends longevity and prevents disease-related protein aggregation through PA28γ-induced proteasomes. Nature Aging, 3(5), 546–566. https://doi.org/10.1038/s43587-023-00383-4 Roberts, L. A., Raastad, T., Markworth, J. F., et al. (2015). Post-exercise cold water immersion attenuates acute anabolic signalling and long-term adaptations in muscle to strength training. Journal of Physiology, 593(18), 4285–4301. https://doi.org/10.1113/jp270570 Janský, L., Pospíšilová, D., Honzová, S., et al. (1996). Immune system of cold-exposed and cold-adapted humans. European Journal of Applied Physiology, 72(5–6), 445–450. https://doi.org/10.1007/bf00242274 Wang, Y., Li, S., Zhang, Y., et al. (2021). Heat and cold therapy reduce pain in patients with delayed onset muscle soreness: A systematic review and meta-analysis of 32 randomized controlled trials. Physical Therapy in Sport, 48, 177–187. https://doi.org/10.1016/j.ptsp.2021.01.004 Qu, C., Wu, Z., Xu, M., et al. (2020). Cryotherapy models and timing-sequence recovery of exercise-induced muscle damage in middle- and long-distance runners. Journal of Athletic Training, 55(4), 329–335. https://doi.org/10.4085/1062-6050-529-18 Saari, T. J., Raiko, J., U-Din, M., et al. (2020). Basal and cold-induced fatty acid uptake of human brown adipose tissue is impaired in obesity. Scientific Reports, 10, 1–11. https://doi.org/10.1038/s41598-020-71197-2 Brenner, I. K., Castellani, J. W., Gabaree, C., et al. (1999). Immune changes in humans during cold exposure: Effects of prior heating and exercise. Journal of Applied Physiology, 87(2), 699–710. https://doi.org/10.1152/jappl.1999.87.2.699 Duong, H., & Patel, G. (2024). Hypothermia. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK545239/ Doets, J. J. R., Topper, M., & Nugter, A. M. (2021). A systematic review and meta-analysis of the effect of whole body cryotherapy on mental health problems. Complementary Therapies in Medicine, 63, 102783. https://doi.org/10.1016/j.ctim.2021.102783 Espeland, D., de Weerd, L., & Mercer, J. B. (2022). Health effects of voluntary exposure to cold water – a continuing subject of debate. International Journal of Circumpolar Health, 81(1). https://doi.org/10.1080/22423982.2022.2111789 Fuchs, C. J., Kouw, I. W. K., Churchward-Venne, T. A., et al. (2020). Postexercise cooling impairs muscle protein synthesis rates in recreational athletes. Journal of Physiology, 598(4), 755–772. https://doi.org/10.1113/jp278996 Pretorius, T., Bristow, G. K., Steinman, A. M., & Giesbrecht, G. G. (2006). Thermal effects of whole head submersion in cold water on nonshivering humans. Journal of Applied Physiology, 101(2), 669–675. https://doi.org/10.1152/japplphysiol.01241.2005 Keramidas, M. E., & Botonis, P. G. (2021). Short-term sleep deprivation and human thermoregulatory function during thermal challenges. Experimental Physiology, 106(5), 1139–1148. https://doi.org/10.1113/EP089467 Bleakley, C. M., Bieuzen, F., Davison, G. W., & Costello, J. T. (2014). Whole-body cryotherapy: Empirical evidence and theoretical perspectives. Open Access Journal of Sports Medicine, 5, 25–36. https://doi.org/10.2147/OAJSM.S41655 Machado, A. F., Ferreira, P. H., Micheletti, J. K., et al. (2016). Can water temperature and immersion time influence the effect of cold water immersion on muscle soreness? A systematic review and meta-analysis. Sports Medicine, 46(4), 503–514. https://doi.org/10.1007/s40279-015-0431-7 Wilson, L. J., Cockburn, E., Paice, K., et al. (2018). Recovery following a marathon: A comparison of cold water immersion, whole body cryotherapy and a placebo control. European Journal of Applied Physiology, 118(1), 153–163. https://doi.org/10.1007/s00421-017-3757-z Degroot, D. W., & Kenney, W. L. (2007). Impaired defense of core temperature in aged humans during mild cold stress. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 292(1), R103–R108. https://doi.org/10.1152/ajpregu.00074.2006 Blondin, D. P., Labbé, S. M., Tingelstad, H. C., et al. (2014). Increased brown adipose tissue oxidative capacity in cold-acclimated humans. Journal of Clinical Endocrinology & Metabolism, 99(3), E438–E446. https://doi.org/10.1210/jc.2013-3901 Hanssen, M. J. W., Hoeks, J., Brans, B., et al. (2015). Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus. Nature Medicine, 21(8), 863–865. https://doi.org/10.1038/nm.3891 Johnson, J. M., Minson, C. T., & Kellogg, D. L., Jr. (2014). Cutaneous vasodilator and vasoconstrictor mechanisms in temperature regulation. Comprehensive Physiology, 4(1), 33–89. https://doi.org/10.1002/cphy.c130015 Westpac Marine. (2024). Hypothermia chart. Retrieved September 14, 2024, from https://westpacmarine.com/samples/hypothermia_chart.php Adnan, H., William, J. R., & Anthony, W. B. (2018). Enhancing the physiology and effectiveness of whole-body cryotherapy treatment for sports recovery by establishing an optimum protocol: A review of recent perspectives. Journal of Physical Medicine, 1(1). https://doi.org/10.36959/942/338 Gibas-Dorna, M., Checinska, Z., Korek, E., et al. (2016). Variations in leptin and insulin levels within one swimming season in non-obese female cold water swimmers. Scandinavian Journal of Clinical and Laboratory Investigation, 76(6), 486–491. https://doi.org/10.1080/00365513.2016.1201851 Blondin, D. P., Tingelstad, H. C., Mantha, O. L., Gosselin, C., & Haman, F. (2014). Maintaining thermogenesis in cold exposed humans: Relying on multiple metabolic pathways. Comprehensive Physiology, 4(4), 1383–1402. https://doi.org/10.1002/cphy.c130043 Eglin, C. M., & Tipton, M. J. (2005). Repeated cold showers as a method of habituating humans to the initial responses to cold water immersion. European Journal of Applied Physiology, 93(5–6), 624–629. https://doi.org/10.1007/s00421-004-1239-6 Srámek, P., Simecková, M., Janský, L., Savlíková, J., & Vybíral, S. (2000). Human physiological responses to immersion into water of different temperatures. European Journal of Applied Physiology, 81(5), 436–442. https://doi.org/10.1007/s004210050065 Pawłowska, M., Mila-Kierzenkowska, C., Boraczyński, T., et al. (2021). The effect of submaximal exercise followed by short-term cold-water immersion on the inflammatory state in healthy recreational athletes: A cross-over study. Journal of Clinical Medicine, 10(18), 4239. https://doi.org/10.3390/jcm10184239 Rymaszewska, J., Lion, K. M., Pawlik-Sobecka, L., et al. (2020). Efficacy of the whole-body cryotherapy as add-on therapy to pharmacological treatment of depression: A randomized controlled trial. Frontiers in Psychiatry, 11. https://doi.org/10.3389/fpsyt.2020.00522 Kunutsor, S. K., Lehoczki, A., & Laukkanen, J. A. (2024). The untapped potential of cold water therapy as part of a lifestyle intervention for promoting healthy aging. GeroScience. https://doi.org/10.1007/s11357-024-01295-w Fink, W. J., Costill, D. L., & Van Handel, P. J. (1975). Leg muscle metabolism during exercise in the heat and cold. European Journal of Applied Physiology and Occupational Physiology, 34(3), 183–190. https://doi.org/10.1007/BF00999931 Bergh, U., & Ekblom, B. (1979). Physical performance and peak aerobic power at different body temperatures. Journal of Applied Physiology, 46(5), 885–889. https://doi.org/10.1152/jappl.1979.46.5.885 Cunningham, J. J., Gulino, M. A., Meara, P. A., & Bode, H. H. (1985). 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10-07
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Trailer

Klei drinken reinigt je lichaam, intermittent fasting helpt met afvallen en koffieklysma's zijn goed voor je darmen. Het wemelt tegenwoordig van de trends en hypes, die je zouden helpen om gezonder oud te worden. Maar hoe weet je wat klopt? Je kunt er eindeloos over lezen of alles zelf testen. Of je besteedt het allebei uit door deze podcast te luisteren. In Lang Zal Je Leven voorziet dokter Alexander je van de theorie over gezondheidsclaims. Praktijkexpert Tom ondervindt alles aan den lijve. Allemaal zodat jij kan vieren dat je alle kennis op een presenteerblaadje krijgt. Lang Zal Je Leven!See omnystudio.com/listener for privacy information.

09-30
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