NIEHS Superfund Research Program - Research Brief Podcasts

The National Institute of Environmental Health Sciences (NIEHS) Superfund Research Program (SRP) produces a monthly Research Brief Podcast that highlights the research of SRP grantees. The SRP is a network of university grants that seek solutions to the complex health and environmental issues associated with the nation's hazardous waste sites. The research conducted by the SRP is a coordinated effort with the Environmental Protection Agency, which is the federal entity charged with cleaning up the worst hazardous waste sites in the country. For information on how NIEHS interacts with its online visitors, check out its Web Policies - http://www.niehs.nih.gov/about/od/ocpl/policies/

User-friendly Technology Detects NDMA in Water

A new technology, developed by researchers at the NIEHS-funded Massachusetts Institute of Technology Superfund Research Program Center, can detect the contaminant N-nitrosodimethylamine (NDMA) in water. This breakthrough tool offers a quick way to monitor NDMA by triggering a visible color change when light interacts with the contaminated solution.

11-06
04:26

Early Life Exposures May Shape Infant Immune System

Exposure to certain chemicals during early pregnancy may influence how a baby’s immune system develops, according to a study partly funded by the NIEHS Superfund Research Program (SRP). The scientists discovered that some per- and polyfluoroalkyl substances (PFAS) and metals may alter how an infant’s immune system responds to environmental triggers.

09-04
04:48

Pyrite Improves Electrochemical System for Removing a Chemical Mixture

Adding a common mineral, pyrite, to an electrochemical system can simultaneously remove organic and heavy metal contaminants from groundwater, according to a study funded in part by the NIEHS Superfund Research Program (SRP). Led by Akram Alshawabkeh, Ph.D., researchers at the Northeastern University SRP Center found that combining two types of remediation techniques – one that relies on applying an electrical current to destroy contaminants and one that uses minerals to adsorb contaminants – removed pollutants more effectively than either strategy alone.

08-07
04:43

Environmental Factors Alter PFAS Removal by Specialized Nanomaterials

Researchers funded by the NIEHS Superfund Research Program (SRP) revealed how characteristics of water treatment systems may alter the ability of novel nanomaterials to remove PFAS. Scientists should be aware of factors like water pH ' a measure of acidic or basic conditions ' or salt level to ensure that these nanomaterials effectively remove PFAS in aqueous environments, according to the team based at the State University of New York at Buffalo.

07-10
04:03

High Seafood Diet May Lead to Increased PFAS Exposure

A study funded by the NIEHS Superfund Research Program (SRP) found that consuming some types of commercial seafood in high quantities may increase the risk of PFAS exposure. Led by Celia Chen, Ph.D., Kate Crawford, Ph.D., and Megan Romano, Ph.D., at Dartmouth College, the research team believes their findings can support the development of consumption guidelines to protect communities from further PFAS exposure.

06-05
04:45

Engineering Hydrogel Beads to Enhance Bioremediation of Groundwater Contaminant

Oregon State University scientists and engineers developed an approach to cleaning polluted groundwater that uses tiny beads containing chemical-eating bacteria. In this study, funded by the NIEHS Superfund Research Program (SRP), the team identified a formula to maximize bead durability and bioremediation, or the removal of contaminants using bacteria.

05-01
04:53

Tracking Mercury Conversion and Distribution in Aquatic Environments

NIEHS Superfund Research Program (SRP)-funded researchers, led by Heileen Hsu-Kim, Ph.D., of the Duke University SRP Center, provided insight into how and at what timescale mercury changes within a wetland ecosystem. They found mercury from different sources is converted into other mercury forms that eventually have similar properties. This finding can inform environmental management or pollution control strategies.

04-03
05:43

Using Earth Materials to Remove Metals Near Abandoned Mines

NIEHS Superfund Research Program (SRP)-funded researchers developed a new strategy that uses limestone and a naturally occurring mineral to clean up water contaminated with arsenic and uranium — two of the most frequently detected drinking water pollutants in Tribal communities.

03-06
04:03

New Model Estimates the Effects of Dioxin on Liver Cholesterol

Scientists funded partly by the NIEHS Superfund Research Program (SRP) developed a computer model to determine the health effects of exposure to dioxins. Researchers use the model to combine data on exposures and on known health outcomes to assess the overall risk chemicals could pose to health.For this study, researchers at the Michigan State University SRP Center and Emory University created a computational model to show how the highly toxic chemical 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) affects biological processes that increase cholesterol levels in the liver.

02-07
05:59

Mapping Microbe Interactions That Support PCB-Degrading Bacteria

Researchers partially funded by the NIEHS Superfund Research Program (SRP) mapped interactions between microbes that may support the growth of certain bacteria that degrade polychlorinated biphenyls (PCBs), a harmful contaminant. By harnessing those microbial relationships, researchers could improve the bioremediation, or bacterial breakdown, of PCBs from the environment, according to a team led by Timothy Mattes, Ph.D., University of Iowa SRP Center.

01-10
04:23

Environmentally Persistent Free Radicals, PAHs Interact to Increase Toxicity of Particulate Mixtures

Toxic air pollutants called environmentally persistent free radicals (EPFRs) may react with certain polycyclic aromatic hydrocarbons (PAHs) on the surface of airborne particles to form more toxic chemicals, according to researchers funded by the NIEHS Superfund Research Program (SRP). The study, led by Slawomir Lomnicki, Ph.D., of the Louisiana State University SRP Center, demonstrated that interactions between components of fine particulate matter mixtures may enhance their overall toxicity.

12-12
04:38

High-Temperature Biochar for Arsenic Remediation

Adding biochar produced at a high temperature may be an effective way to immobilize arsenic in sediment, according to researchers partially funded by the NIEHS Superfund Research Program (SRP). The study, led by Owen Duckworth, Ph.D., of the University of North Carolina at Chapel Hill SRP Center, in partnership with researchers from the Luiz de Queiroz College of Agriculture, University of São Paulo, Brazil, also provided further insight into the conditions that influenced the effectiveness of biochar for soil remediation.

11-01
04:14

Mechanism of Cadmium-induced Neurotoxicity, Potential Treatment Revealed

A particular class of extracellular vesicles protects against neurotoxicity caused by cadmium exposure, according to an NIEHS Superfund Research Program (SRP)-funded study. Extracellular vesicles are small packages of fats, nucleic acids, or proteins that allow cells to communicate with each other and support numerous cellular functions.

10-04
04:13

Modified Iron Particles Could Improve Bioremediation of PFAS

Iron particles coated in a nontoxic material may enhance PFAS degradation by a certain bacterium, according to researchers funded by the NIEHS Superfund Research Program. The study could inform bioremediation efforts that harness the microbe, known as Acidimicrobium Strain A6, for cleaning up contaminated soil, sediments, and aquifers.

09-06
05:29

Benzene Exposure During Pregnancy Affects Later-Life Metabolic Health

Prenatal exposure to the air pollutant benzene may lead to a higher risk of metabolic diseases later in life, according to a study in mice partially funded by the NIEHS Superfund Research Program (SRP). Benzene affects neurodevelopment, predisposing offspring to harmful metabolic effects, according to a research team led by Marianna Sadagurski, Ph.D., of the Wayne State University SRP Center.

08-02
04:42

Cadmium-Linked Inflammation Increases the Severity of Lung Infection

Researchers funded in part by the NIEHS Superfund Research Program (SRP) uncovered a key mechanism explaining how inflammation caused by cadmium exposure makes lung infections more severe and deadly.

07-12
06:18

Exposure to PCBs During Nursing Leads to Temporary Diabetes-Related Health Effect

Exposure to synthetic chemicals called polychlorinated biphenyls (PCBs) through a mother's milk could cause short-term glucose intolerance in offspring, according to a study by researchers from the University of Kentucky (UK) and funded by the NIEHS Superfund Research Program (SRP). Intolerance to glucose, signified by high blood levels of the sugar, is a hallmark of diabetes. The study, conducted with mice, builds on earlier SRP-funded work by the same group that found connections between maternal PCB exposure and diabetes risk factors in progeny.

06-07
05:29

Fighting Fluorine with Fluorine: New Materials Remove PFAS from Groundwater

Researchers funded by the NIEHS Superfund Research Program (SRP) created a novel class of materials that can attract and remove per- and polyfluoroalkyl substances (PFAS) from water. According to the authors, the new technology — called Fluor Mop — can be regenerated, reused, and is potentially less expensive than current remediation strategies.

05-03
06:13

Mimicking Molecules Made by Bacteria to Remove Metals From Water

NIEHS Superfund Research Program (SRP)-funded scientists developed a method to extract metals from water using synthetic molecules inspired by those produced by bacteria. The biodegradable molecules, called rhamnolipids, could one day be used to remove toxic metals or extract rare and valuable elements from aqueous mining and industrial waste.

04-05
04:12

New Model Estimates PFAS Exposures From Contaminated Drinking Water

Researchers partially funded by the NIEHS Superfund Research Program (SRP) developed a model to estimate individual exposure to four per- and polyfluoroalkyl substances (PFAS) commonly found in drinking water. The model integrates published data from multiple studies on PFAS levels in human blood along with measured PFAS concentrations in drinking water. Tools for estimating PFAS exposure from contaminated drinking water can inform public health risk assessments and advisories.

03-08
06:39

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