Neurology Today in 5

Joseph E. Safdieh, MD, FAAN, Editor-in-Chief of Neurology Today highlights the most noteworthy and newsworthy neurology stories in the issue.

Biomarker for migraine; posterior cortical atrophy gene therapy for neuromuscular disorders

Neurology Today Editor-in-chief Joseph E. Safdieh, MD, FAAN, discusses a new study showing retinal vascular perfusion as a migraine biomarker, clinical and pathophysiological correlates of posterior cortical atrophy, and advances in gene therapies for neuromuscular disorders.

02-12
04:30

Antipsychotic for dementia-related agitation, contaminated water at Camp Lejeune associated with elevated risk for Parkinson’s, gene variant confers resilience against autosomal dominant Alzheimer’s.

In this week’s podcast, Neurology Today’s editor-in-chief discusses the FDA approval of an antipsychotic for agitation in dementia, elevated risk for Parkinson’s in Camp Lejeune Marines exposed to contaminated water, a gene variant delays the onset of symptoms in man with autosomal dominant Alzheimer’s. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

06-15
05:29

Novel PET radiotracer, GLP-1s and dementia risk, green space benefits

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about a PET radiotracer that shows intranasally delivered insulin enters the brain, GLP-1s and dementia risk in people with Type 2 diabetes, and how exposure to green space may reduce the risk of neurodevelopmental delays in children.

10-16
04:49

Pegivirus’ role in Parkinson’s disease, GLP-1s and idiopathic intracranial hypertension, geographic spread of epilepsy specialists

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about pegivirus’s potential role in Parkinson’s disease pathology, the impact of GLP-1 receptor agonistst on idiopathic intracranial hypertension, and the geographic spread of epilepsy specialists.

10-02
04:59

Food deserts and stroke risk, physical activity in Parkinson’s disease, rimegepant for migraine

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about the relationship between income, “food deserts,” and stroke risk; why staying active may reduce cognitive decline in patients with Parkinson's disease; and how initiating rimegepant for migraine could help reduce opioid and butalbital use. 

09-18
04:51

Parkinson’s and dementia with Lewy bodies blood test, CAR T-cell therapy for glioblastoma, wireless EEG

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about a promising blood test to distinguish Parkinson’s disease from dementia with Lewy bodies, how CAR T-cell therapies are showing potential for patients with glioblastoma, and a new wireless electroencephalogram device that can even monitor young children with epilepsy.

09-04
04:27

Small fiber neuropathy, Dr. Merit Cudkowicz, work-life balance for families of neurologists

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about whether small fiber neuropathy is an autoimmune disorder; Merit Cudkowicz, MD, MSc, FAAN, recipient of this year’s AAN Lifetime Achievement Award for Clinically Relevant Research; and how neurologist couples pursue work-life balance.

08-21
03:52

Divisive treatment for cluster headache, head positioning before thrombectomy, new series, “Neurology in America”

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about eptinezumab, a treatment for episodic cluster headache; how positioning the head flat before a thrombectomy benefited patients with large vessel occlusion stroke; and what rural neurology looks like in 2025, the first story in our new series, Neurology in America.

08-07
04:10

New treatment for giant-cell arteritis, links between oral and brain health, an emerging meningitis B vaccine

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles about upadacitinib, a new treatment for giant-cell arteritis; growing evidence linking oral health to a higher risk of neurologic conditions; and why a trial of a new meningitis B vaccine drew a mixed response.

07-17
04:34

Telomere length and and risk for neurologic disorders, impact of research cuts on promotion/tenure, herpes zoster vaccine and dementia

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles on the association of shortened telomeres on risk for stroke, late-life depression and dementia; affect of research funding cuts on tenure/promotion opportunities; and  herpes zoster vaccine and reduced dementia risk.

07-03
04:51

Post-TIA fatigue, neurologic complications of measles, CDC surveillance of epilepsy program dismantled.

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles studies showing persistent fatigue after TIA, the neurologic complications of measles, and the impact of the dismantling of a CDC surveillance program of epilepsy.

06-19
04:14

Post-TIA fatigue, neurologic complications of measles, CDC surveillance of epilepsy program dismantled.

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles studies showing persistent fatigue after TIA, the neurologic complications of measles, and the impact of the dismantling of a CDC surveillance program of epilepsy.

06-05
04:27

Advances in cell therapies for Parkinson’s, GLP-1 agonists and dementia risk, FDA accelerated approvals for neurology drugs

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles about early studies finding dopamine cellular therapies were safe and tolerable for patients with Parkinson’s, use of GLP-1 agonists were associated with reduced dementia risks, and the FDA use of accelerated approvals for several neurology drugs are under scrutiny. 

05-15
04:14

Microplastics in brain, salary gap in neurology, the neurology of space

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles finding microplastics in the brain postmortem linked to dementia, the salary gap between men and women neurologies, and neurologists studying the impact of microgravity on the brain.

05-01
04:16

Impact of high-dose Vitamin D on MS relapse, the role of AI in neurology education, and a 4D animal model that shows precursors of MS lesions before they appear.

In this episodeof Neurology Today in 5, Neurology Today editor-in-chief Joseph E. Safdieh, MD, FAAN, discusses a large trial that found high-dose Vitamin D reduced MRI evidence of disease activity in patients with clinically isolated syndrome or early relapsing MS; an animal brain map, revealing changes in inflammation, immune activity, and cell repair that preceded the appearance of MS lesions; and a discussion of the challenges and opportunities of using AI in neurology education.

04-17
04:41

New approved drug for neurofibromatosis 1 with plexiform neurofibromas, multidisciplinary clinics in neurology, impact of cuts to DEI research grants

In this week’s podcast, Neurology Today’s editor-in-chief highlights articles on the newly approved drug for neurofibromatosis 1 with plexiform neuromas in adults, how neurology practices are integrating with multiple subspecialties, and the impact of federal cuts to DEI grants and research.

04-03
04:35

Impact of NIH cuts on neurology research, response to ACP’s guideline on migraine, an updated position on seizures, driver licensure, and medical reporting

In this week’s podcast, Neurology Today’s editor-in-chief highlights articles on the impact of NIH cuts to indirect research costs, response to a new guideline on migraine prevention from ACP, and an updated position statement from the AAN on seizures, driver licensures, and medical reporting.

03-20
05:06

Lifetime burden of dementia, hidden features on EEGs for epilepsy detection, neurology-trained pharmacists

In this week’s podcast, Neurology Today’s editor-in-chief highlights articles on the larger lifetime burden of dementia than projected, an AI-fueled program that detects hidden features in EEGs for epilepsy detection, and neurology-trained pharmacists who are working with neurology departments.

03-06
04:44

IVF and MS relapse, community-based neurologists doing clinical research, and the loneliness protein implicated in brain function.

In this week’s podcast, Neurology Today’s editor-in-chief highlights articles on new data on IVF safety for women with MS, an elevated protein associated with loneliness, social isolation and brain function, and the role of community-based neurologists in drug development.  

02-20
05:25

Remote neurology education, tirzepatide for obesity-related OSA, artificial intelligence for glioma assessment

In this week’s podcast, Neurology Today’s editor-in-chief highlights articles on the pros and cons of virtual neurology education, the FDA approval of tirzepatide for obesity-related obstructive sleep apnea, and the promise of AI for glioma assessment.  

02-06
04:49

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