New Books in Neuroscience

Inside our heads we carry around an infinite and endlessly unfolding map of the world. Navigation is one of the most ancient neural abilities we have―older than language. In Dark and Magical Places: The Neuroscience of Navigation (Norton, 2022), Christopher Kemp embarks on a journey to discover the remarkable extent of what our minds can do. Fueled by his own spatial shortcomings, Kemp describes the brain regions that orient us in space and the specialized neurons that do it. Place cells. Grid cells. He examines how the brain plans routes, recognizes landmarks, and makes sure we leave a room through a door instead of trying to leave through a painting. From the secrets of supernavigators like the indigenous hunters of the Bolivian rainforest to the confusing environments inhabited by people with place blindness, Kemp charts the myriad ways in which we find our way and explains the cutting-edge neuroscience behind them. How did Neanderthals navigate? Why do even seasoned hikers stray from the trail? What spatial skills do we inherit from our parents? How can smartphones and our reliance on GPS devices impact our brains? In engaging, engrossing language, Kemp unravels the mysteries of navigating and links the brain’s complex functions to the effects that diseases like Alzheimer’s, types of amnesia, and traumatic brain injuries have on our perception of the world around us. A book for anyone who has ever felt compelled to venture off the beaten path, Dark and Magical Places is a stirring reminder of the beauty in losing yourself to your surroundings. And the beauty in understanding how our brains can guide us home. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

There is a hidden addiction plaguing humanity right now: revenge. Researchers have identified retaliation in response to real and imagined grievances as the root cause of most forms of human aggression and violence. From vicious tweets to road rage, murder-suicide, and armed insurrection, perpetrators almost always see themselves as victims seeking justice. Chillingly, recent behavioral and neuroimaging studies of the human brain show that harboring a personal grievance triggers revenge desires and activates the neural pleasure and reward circuitry of addiction.Although this behavior is ancient and seems inevitable, by understanding retaliation and violence as an addictive brain-biological process, we can control deadly revenge cravings and save lives. In The Science of Revenge: Understanding the World's Deadliest Addiction—and How to Overcome It (Random House, 2025), Yale violence researcher and psychiatry lecturer James Kimmel, Jr., JD, uncovers the truth behind why we want to hurt the people who hurt us, what happens when it gets out of hand, and how to stop it.Weaving neuroscience, psychology, sociology, law, and human history with captivating storytelling, Dr. Kimmel reveals the neurological mechanisms and prevalence of revenge addiction. He shines an unsparing light on humanity’s pathological obsession with revenge throughout history; his own struggle with revenge addiction that almost led him to commit a mass shooting; America’s growing addiction to revenge as a special brand of justice; and the startlingly similar addictive behaviors and motivations of childhood bullies, abusive partners, aggrieved employees, sparring politicians, street gang members, violent extremists, mass killers, and tyrannical dictators. He also reveals the amazing, healing changes that take place inside your brain and body when you practice forgiveness. Emphasizing the necessity of proven public health approaches and personal solutions for every level of revenge addiction, he offers urgent, actionable information and novel methods for preventing and treating violence. James Kimmel, Jr. is an assistant clinical professor in psychiatry at the Yale School of Medicine, a lawyer, and the founder and co-director of the Yale Collaborative for Motive Control Studies. Caleb Zakarin is editor of the New Books Network. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

The human mind has the curious, even mysterious, ability to generate thoughts about things with which we are not in causal contact, such as when we think about yesterday’s tennis final, or Aristotle, or unicorns. Naturalizing mental content has usually meant explaining how this is possible in terms that eliminate the mystery while retaining commitment to a substantive relationship between mind and world that undergirds this ability. In Deflating Mental Representation (MIT Press), Frances Egan argues that we should give up this commitment in favor of a naturalistic account that treats attributions of content as abstract glosses of neural mechanisms. According to Egan, who is emeritus professor of philosophy at Rutgers University—New Brunswick, representational glosses play ineliminable roles in commonsense psychology and our explanations of human behavior, but they should not be taken literally. Egan forcefully challenges many leading theories of mental representation, making her book a must-read for those interested in the concept of mental representation in the cognitive sciences. Deflating Mental Representation is available open-access and free here.  Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Octopuses can open jars to get food, and chimpanzees can plan for the future. An IBM computer named Watson won on Jeopardy! and Alexa knows our favorite songs. But do animals and smart machines really have intelligence comparable to that of humans? In Bots and Beasts: What Makes Machines, Animals, and People Smart? (MIT Press, 2021), Paul Thagard looks at how computers (“bots”) and animals measure up to the minds of people, offering the first systematic comparison of intelligence across machines, animals, and humans. Thagard explains that human intelligence is more than IQ and encompasses such features as problem solving, decision making, and creativity. He uses a checklist of twenty characteristics of human intelligence to evaluate the smartest machines—including Watson, AlphaZero, virtual assistants, and self-driving cars—and the most intelligent animals—including octopuses, dogs, dolphins, bees, and chimpanzees. Neither a romantic enthusiast for nonhuman intelligence nor a skeptical killjoy, Thagard offers a clear assessment. He discusses hotly debated issues about animal intelligence concerning bacterial consciousness, fish pain, and dog jealousy. He evaluates the plausibility of achieving human-level artificial intelligence and considers ethical and policy issues. A full appreciation of human minds reveals that current bots and beasts fall far short of human capabilities. Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Not a lot of authors go from spending their early twenties homeless and addicted to cocaine to becoming one of the world’s leading researchers on the neuroscience of addiction. But Dr. Judith Grisel, in her new book Never Enough: The Neuroscience and Experience of Addiction (Doubleday, 2019), uses her personal story to illuminate the ways in which the brain, in collusion with social and biological factors, makes addiction possible. In our discussion, Grisel outlines the effects of different drugs, explains the “three laws of psychopharmacology,” and wonders if we’ll ever find medicine’s “holy grail” – a cure for addiction. Emily Dufton is the author of Grass Roots: The Rise and Fall and Rise of Marijuana in America (Basic Books, 2017). A drug historian and writer, she edits Points, the blog of the Alcohol and Drugs History Society. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

The vagus nerve is fundamental to our health and vitality, coordinating critical functions from the precise heartbeat we need to exercise or rest to the balance of appetite and digestion. Made up of 200,000 fibers, the vagus nerve sends thousands of electrical signals every second between your brain and your most important organs. Yet despite its essential role in life, important vagus nerve functions have eluded centuries of scientific investigation. Now neurosurgeon and researcher Dr. Kevin Tracey has discovered the previously unknown power of the vagus nerve to reverse inflammation, balance the immune system, treat chronic illness, and keep our organs humming together in harmony.In The Great Nerve: The New Science of the Vagus Nerve and How to Harness Its Healing Reflexes (Penguin, 2025), Dr. Tracey shows us how stimulating the vagus nerve with a tiny electrical implant has the potential to reverse life-altering diseases like rheumatoid arthritis, inflammatory bowel disease, lupus, MS, diabetes, obesity, stroke, depression, Alzheimer’s and Parkinson’s. If this sounds too good to believe, Dr. Tracey shares stories of patients who have gone from being nearly bedridden to running and dancing, along with the science that makes possible these recoveries. He also explains the evidence for lifestyle strategies like ice baths, meditation, exercise, and breathwork that can maintain and improve vagus nerve function.By opening the door to the new field of neuroimmunology, The Great Nerve  not only revolutionizes how we understand and treat disease, it gives us unprecedented hope for our health. This is the story of your body’s ability to heal itself. This interview was conducted by Dr. Miranda Melcher whose book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. You can find Miranda’s interviews on New Books with Miranda Melcher, wherever you get your podcasts. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Because brainwashing affects both the world and our observation of the world, we often don’t recognize it while it’s happening—unless we know where to look. As Rebecca Lemov writes in The Instability of Truth, “Brainwashing erases itself.” What we call brainwashing is more common than we think; it is not so much what happens to other people as what can happen to anyone. The Instability of Truth exposes the myriad ways our minds can be controlled against our will, from the brainwashing techniques used against American POWs in North Korea to the “soft” brainwashing of social media doomscrolling and behavior-shaping. In our increasingly data-driven world, anyone can fall victim to mind control. Lemov identifies invasive forms of emotional engineering that exploit trauma and addiction to coerce and persuade in everyday life. Tracing the word “brainwashing” from deep in the files of an operative of the U.S. Office of Strategic Services in the 1950s to the pioneering research of Robert Jay Lifton, to the public trials of cult leaders and the case of Patty Hearst, Lemov also studies how the idea of mind control has spread across the globe and penetrated courtrooms, secret labs, military schools, and today’s digital sites. The Instability of Truth offers lessons from mind-control episodes past and present. Truth is always subject to question in more mundane walks of life than most people believe, and Lemov equips us for the increasing challenges we face from social media, AI, and an unprecedented, global form of surveillance capitalism. The Instability of Truth develops a rigorous new understanding of both brainwashing’s paradoxes and its emotional roots, by giving voice to brainwashers, the brainwashed, and third-party observers alike. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

How can I help my students not only learn my course material but also retain and transfer that information? This is a question that has plagued and intrigued teachers for centuries. In Smart Teaching Stronger Learning: Practical Tips for 10 Cognitive Scientists, the authors provide their readers with evidence-based practices for immediate classroom implementation. Their premise is that small changes can lead to powerful results. In this approachable book, each chapter is written by a cognitive scientist who is currently teaching. The chapters introduce a concept, describe how to implement the concept in your classroom, and provide multiple resources for further study. The book is consciously formatted to be a quick read (approximately 100 pages) and provides valuable information for anyone who is interested in helping someone else or themselves learn. Teachers, parents, coaches, and lifelong learners will benefit from these strategies. In this episode, Dr. Pooja Agarwal, Dr. Cynthia Nebel, and Dr. Veronica Yan, discuss each of the topics presented in Smart Teaching Stronger Learning: Practical Tips for 10 Cognitive Scientists. Dr. Nebel discusses how learning increases motivation by discussing the Effective Teaching Cycle: Motivation, Scaffolding, and Reinforcement. Dr. Yan discusses the importance of interleaving. Dr. Agarwal provides an overview of the other chapter topics: retrieval practice, early childhood education, metacognition, concept mapping, learning transfer, engagement, and neuromyths. Throughout the episode, Drs. Agarwal, Nebel, and Yan share how these tips have been implemented in their classrooms, and how these same concepts can universally be applied to learning in general. Dr. Pooja Agarwal is the author of the books Powerful Teaching and Smart Teaching Stronger Learning: Practical Tips for 10 Cognitive Scientists. She is editor-in-chief of Retrievalpractice.org and is an Associate Professor of Psychology at the Berklee College of Music in Boston, MA. Dr. Cynthia Nebel is the Director of Learning Services and an Associate Professor of Psychiatry and Behavioral Neuroscience at St. Louis University School of Medicine in St. Louis, MO. Dr. Veronica Yan is an Associate Professor of Educational Psychology at the University of Texas at Austin in Austin, TX. Dr. Anne-Marie Verenna is a Professor of Biology and the Scholarship of Teaching and Learning Faculty Fellow at Delaware County Community College in Media, PA. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Picturing Aura: A Visual Biography (MIT Press, 2025) by Dr. Jeremy Stolow is the first book of its kind: an extended historical, anthropological, and philosophical study of modern efforts to visualize the hidden radiant force encompassing the living body known as our aura. This rich, interdisciplinary study by Dr. Stolow chronicles the rise and global spread of modern instruments and techniques of picturing aura, from the late nineteenth century to the present day, exploring how its images are put to work in the diverse realms of psychical research, esotericism, art photography, popular culture, and the New Age alternative medical and spiritual marketplace.At their core, pictures of auras are boundary objects that operate simultaneously in multiple conceptual and practical realms, serving varying goals of making art, healing bodies, and exploring the cosmos. Drawing on extensive archival as well as field research, Stolow reconstructs a global history of this boundary-crossing enterprise through its evolving media technologies, markets, and cultural arenas. It is a story shaped through exchanges among professionals and amateurs, scientists and occultists, countercultural artists and entrepreneurs, metropolitans and hinterland figures. With more than 60 full-color illustrations, Picturing Aura brings to light a remarkable, entangled history of picture-making that challenges settled assumptions about religion, art, and science. This interview was conducted by Dr. Miranda Melcher whose book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. You can find Miranda’s interviews on New Books with Miranda Melcher, wherever you get your podcasts. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Who benefits and who loses when emotions are described in particular ways? How do metaphors such as "hold on" and "let go" affect people's emotional experiences? Banned Emotions: How Metaphors Can Shape What People Feel (Oxford UP, 2019), written by neuroscientist-turned-literary scholar Laura Otis, draws on the latest research in neuroscience and psychology to challenge popular attempts to suppress certain emotions. This interdisciplinary book breaks taboos by exploring emotions in which people are said to "indulge" self-pity, prolonged crying, chronic anger, grudge-bearing, bitterness, and spite. By focusing on metaphors for these emotions in classic novels, self-help books, and popular films, Banned Emotions exposes their cultural and religious roots. Examining works by Dante, Dickens, Dostoevsky, Kafka, Forster, and Woolf in parallel with Bridesmaids, Fatal Attraction, and Who Moved My Cheese?, Banned Emotions traces pervasive patterns in the ways emotions are represented that can make people so ashamed of their feelings, they may stifle emotions they need to work through. The book argues that emotion regulation is a political as well as a biological issue, affecting not only which emotions can be expressed, but who can express them, when, and how. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Mice are used as model organisms across a wide range of fields in science today--but it is far from obvious how studying a mouse in a maze can help us understand human problems like alcoholism or anxiety. How do scientists convince funders, fellow scientists, the general public, and even themselves that animal experiments are a good way of producing knowledge about the genetics of human behavior? In Model Behavior: Animal Experiments, Complexity, and the Genetics of Psychiatric Disorders (U Chicago Press, 2018), Nicole C. Nelson takes us inside an animal behavior genetics laboratory to examine how scientists create and manage the foundational knowledge of their field. Behavior genetics is a particularly challenging field for making a clear-cut case that mouse experiments work, because researchers believe that both the phenomena they are studying and the animal models they are using are complex. These assumptions of complexity change the nature of what laboratory work produces. Whereas historical and ethnographic studies traditionally portray the laboratory as a place where scientists control, simplify, and stabilize nature in the service of producing durable facts, the laboratory that emerges from Nelson's extensive interviews and fieldwork is a place where stable findings are always just out of reach. The ongoing work of managing precarious experimental systems means that researchers learn as much--if not more--about the impact of the environment on behavior as they do about genetics. Model Behavior offers a compelling portrait of life in a twenty-first-century laboratory, where partial, provisional answers to complex scientific questions are increasingly the norm. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

What makes one sentence easy to read and another a slog that demands re-reading? Where do you put information you want readers to recall? Drawing on cognitive neuroscience, psychology and psycholinguistics, Writing for the Reader’s Brain (Cambridge University Press, 2025) provides a practical, how-to guide on how to write for your reader. It introduces the five 'Cs' of writing - clarity, continuity, coherence, concision, and cadence - and demonstrates how to use these to bring your writing to life. Dr. Yellowlees Douglas is the founder of ReadersBrain Academy and has spent over twenty-five years teaching writing to everyone from professors to freshmen. This interview was conducted by Renee Hale, who holds a Ph.D. in Chemical Engineering and works in R&D for the food and beverage industry. She is the author of The Nightstorm Files, a voracious reader, and enjoys sharing the joy of new perspectives with listeners. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Today I’m speaking with Ciara Greene, co-author with Gillian Murphy of the new book, Memory Lane: The Perfectly Imperfect Ways We Remember (Princeton UP, 2025). Ciara is associate professor in the School of Psychology at University College Dublin, where she leads the Attention and Memory Laboratory. The scientific study of human memory has become even more relevant in an age where we have every technology under the Sun to alleviate us of the need to remember. It makes sense that we worry about losing the ability to remember today, but even Socrates 2,500 years ago lamented that the recently invented technology of writing harmed people’s ability to remember. Memory not only connects us with our past, but it instructs us in how we should behave, what we should believe, and underlies the patterns of our everyday thoughts. Memory Lane takes readers behind the most up-to-date scientific research on memory. How memory actually works versus how we think it works is a wide chasm, and Ciara and Gillian are excellent guides for bridging the gap. Caleb Zakarin is editor at the New Books Network. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Consciousness Mattering (Bloombury, 2023) presents a contemporary Buddhist theory in which brains, bodies, environments, and cultures are relational infrastructures for human consciousness. Drawing on insights from meditation, neuroscience, physics, and evolutionary theory, it demonstrates that human consciousness is not something that occurs only in our heads and consists in the creative elaboration of relations among sensed and sensing presences, and more fundamentally between matter and what matters. Peter Hershock argues that without consciousness there would only be either unordered sameness or nothing at all. Evolution is consciousness mattering. Shedding new light on the co-emergence of subjective awareness and culture, the possibility of machine consciousness, the risks of algorithmic consciousness hacking, and the potentials of intentionally altered states of consciousness, Hershock invites us to consider how freely, wisely, and compassionately consciousness matters. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Models of the Mind: How Physics, Engineering and Mathematics Have Shaped Our Understanding of the Brain (Bloomsbury, 2021) provides a multifaceted and approachable introduction to theoretical neuroscience. It discusses some major topics of the field, including both the milestones from their history and the currently open questions. It's accessible for a general audience, not expecting any previous knowledge of neuroscience or maths. At the same time, neuroscientists have described it as impressive. According to Gaute Einevoll, professor of brain physics, "this is a book that belongs on the bookshelf of any computational neuroscientist and lots of other people". In our conversation, we covered some of the overarching themes of the book. The constant push and pull between mathematics and biology: mathematical models simplifying complex phenomena and biology pointing out the importance of a specific detail. What efficiency means for a biological system, like the brain. Whether and how much we can assume that an evolved system is efficient. Dr. Grace Lindsay also talked about how science communication has helped her explore and discuss topics not directly related to her research. She started blogging and podcasting during her PhD, which has led to further writing opportunities, including this popular science book. Similar to Models of the Mind, the Lindsay Lab is multidisciplinary: It uses artificial neural networks for psychology, neuroscience, and climate change. In the interview, Dr. Grace Lindsay talked about her decision about the lab's profile She explains the overlap in technologies used for studying visual systems and satellite images. We also hear about examples of how scientists in various fields have taken on research topics related to climate change. Links:  Dr. Grace Lindsay's homepage Lindsay Lab Dr. Grace Lindsay's blog post about Models of the Mind Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Parenting is an emotional rollercoaster – filled with moments of joy, stress, and everything in between. But what if there was a scientific way to understand and navigate these emotions more effectively? In a compelling new podcast episode, Patrick Ney, Lead Trainer at All About Parenting, sits down with Dr. George S. Thompson to explore the fascinating world of polyvagal theory and its profound impact on child development. This conversation is a must-listen for parents, educators, and anyone looking to deepen their understanding of human connection. Dr. Thompson, co-author of Polyvagal Theory and the Developing Child (Norton, 2021) unpacks the science behind how our nervous systems shape our emotions, behaviors, and relationships from birth to adulthood. What You'll Discover in This Episode The Science Behind Connection – Dr. Thompson explains how our nervous system constantly scans for safety and threat, influencing everything from our stress levels to our ability to bond with others. Why Your Child Looks at You for Reassurance – Ever noticed your child checking your face when they’re unsure? That’s social referencing in action. Dr. Thompson breaks down why parental expressions and tone of voice play a crucial role in emotional regulation. Understanding the Three States of the Nervous System – Calm and connected, fight-or-flight, and shutdown – these three states dictate how we react to the world. Learn how to recognize them and respond in ways that foster security and resilience in children. The Power of Co-Regulation – As parents, our nervous systems influence our children’s emotional states. Dr. Thompson shares practical ways to use this knowledge to create a more peaceful and connected home environment. Debunking Polyvagal Theory Myths – Some skeptics claim polyvagal theory lacks scientific backing. Dr. Thompson sets the record straight, drawing on decades of research and clinical application. Why This Episode Matters Many parenting theories focus on discipline, communication, or routines – but few address the biological foundation of emotional security. Polyvagal theory offers a groundbreaking perspective: that a child’s ability to learn, connect, and regulate emotions depends on their sense of safety at a physiological level. This episode dives deep into how this works, offering practical tools that every parent can apply. Dr. Thompson also shares powerful real-life examples, including an in-depth discussion of a child navigating a residential care program. Through this case study, he illustrates how understanding the nervous system can transform how we support children, especially those who have experienced trauma. A Conversation You Won’t Want to Miss Patrick Ney brings his own parenting experiences into the mix, making this discussion both insightful and relatable. Whether you’re new to polyvagal theory or already familiar with it, this episode will leave you with a new appreciation for how our nervous systems shape our lives. If you want to better understand your child’s emotions, improve your parenting approach, or simply gain a fresh perspective on human behavior, tune in now. Listen to the full episode today – your child’s nervous system will thank you! Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Today I began my discussion with Dr. Adrian Perkel about his new book Unlocking The Nature of Human Aggression: A Psychoanalytic and Neuroscientific Approach (Routledge, 2024)  “Aggression is to the mind what the immune system is to the body. It doesn’t seek the fight.” With this perfect mind-body analogy Dr. Perkel proposes a clear way to think theoretically and work clinically with aggression. Throughout the book he links Freud’s formulations of the psyche with contemporary physics and biochemistry. Perkel’s assertion that “Where the aggressive drive goes, so therein lies the solution to many of the psychological problems that present to us in life” is broadly summarized in three essential points: 1. The aggressive drive in the human psyche has the aim of reducing stimuli and excitations brought on by internal and external impingements - it is not looking for a fight. 2. What constitutes a threat or impingement is not necessarily objective - in fact it is always filtered through subjective experience and the UCS associations that are revisited repeatedly giving rise to a lens through which experience is filtered. 3. This experience is driven by memory traces of experience that embed themselves in the UCS and are revisited and hence enacted in a repetitive manner. “My argument is that what wraps all those three points together is that you have life drive needs yes but they're often unfulfilled they're often frustrated and then we need a second mechanism which is what Freud called the death drive.” Acknowledging that the death drive is contentious in psychoanalysis “in neuroscience it's not contested.” I knew going into this interview that we would only discuss a few concepts and elaborations from his book. For more of Dr. Perkel’s writing and webinar on this book please go here and here.  Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

This book is available open access here.  The Brain Abstracted: Simplification in the History and Philosophy of Neuroscience (MIT Press, 2024), Mazviita Chirimuuta argues that the standard ways neuroscientists simplify the human brain to build models for their research purposes mislead us about how the brain actually works. The key issue, instead, is to figure out which details of brain function are relevant for understanding its role in causing behavior; after all, the biological brain is a highly energetically efficient basis of cognition in contrast to the massive data centers driving AI that are based on the simplification that brain functionality is just a matter of neuronal action potentials. Chirimuuta, who is a senior lecturer in philosophy at the University of Edinburgh, also argues for a Kantian-inspired view of neuroscientific knowledge called haptic realism, according to which what we can know about the brain is the product of interaction between brains and the scientific methods and aims that guide how we investigate them. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

Of all the mental illnesses, schizophrenia eludes us the most. No matter the strides scientists have made in neurological research nor doctors have made in psychiatric treatment, schizophrenia remains misunderstood, almost complacently mythologized. Without a reason for the illness, patients feel even more alienated than they already do, families are left hopeless, and doctors struggle to provide accurate care. Steven Lesk, though, after a medical career dedicated to those affected by schizophrenia and a determination to find the answer to its existence, presents a groundbreaking theory that will forever change the lives of the mentally ill.  In Footprints of Schizophrenia: The Evolutionary Roots of Madness (Prometheus, 2023), Lesk threads evolutionary evidence with neurological evidence, turning the mysteries of our minds into a tapestry of logic. With his breakthrough theory and this unprecedented book, Lesk will invite necessary cultural dialogue about this stigmatized illness, provoke new psychiatric and pharmacological research, and provide unequivocal comfort to those afflicted and affected by schizophrenia. Lesk's "primitive organization theory" is based in human evolution, from Neanderthals to Homo sapiens, and the specific changes to our brains after the emergence of language. We have existed in human-like form for six million years, but we've only had language for 50,000; within the vast span of evolutionary time, that's hardly any time at all. Lesk elucidates us to the hormones affected by language, especially dopamine, and with brilliant clarity, connects human evolution, our brain affected by language, and those with schizophrenia whose dopamine doesn't flow in our new, adaptive way. In other words, the twenty million people who have schizophrenia in the world don't suppress dopamine in the way evolution has trained us, so their brains don't process language well and function as if they're in a hallucinatory, delusional dream state. Not only will Lesk's theory focus treatment efforts for schizophrenia, but it will also affect that of other dopamine-related mental illnesses like Alzheimer's, Parkinson's, Huntington's chorea, Tourette's, ADD, and more. Publishing Lesk's work will usher in a new era of psychiatric understanding, one that the field and the public desperately needs. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience

There are many routes to mental well-being. In this groundbreaking book, neuroscientist Camilla Nord offers a fascinating tour of the scientific developments that are revolutionising the way we think about mental health, showing why and how events--and treatments--can affect people in such different ways. In The Balanced Brain: The Science of Mental Health (Princeton UP, 2024), Nord explains how our brain constructs our sense of mental health--actively striving to maintain balance in response to our changing circumstances. While a mentally healthy brain deals well with life's turbulence, poor mental health results when the brain struggles with disruption. But just what is the brain trying to balance? Nord describes the foundations of mental health in the brain--from the neurobiology of pleasure, pain and desire to the role of mood-mediating chemicals like dopamine, serotonin and opioids. She then pivots to interventions, revealing how antidepressants, placebos and even recreational drugs work; how psychotherapy changes brain chemistry; and how the brain and body interact to make us feel physically (as well as mentally) healthy. Along the way, Nord explains how the seemingly small things we use to lift our moods--a piece of chocolate, a walk, a chat with a friend--work on the same pathways in our brains as the latest treatments for mental health disorders. Understanding the cause of poor mental health is one of the crucial questions of our time. But the answer is unique to each of us, and it requires finding what helps our brains rebalance and thrive. With so many factors at play, there are more possibilities for recovery and resilience than we might think. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience