OCW Scholar: Fundamentals of Biology

This collection contains clips from lecture videos of MIT's Introduction to Biology classes. Each video will show the instructor explaining a concept that is covered in the session of the Fundamentals of Biology.

Transformation and Protein Expression

A teaching assistant explains the process of transformation and protein expression, using the example of human insulin expressed in bacterial cells.

06-18
07:30

Polymerase Chain Reaction (PCR)

A teaching assistant explains the polymerase chain reaction (PCR), and examples of its common uses.

06-18
08:35

Pedigrees

A teaching assistant works through a practice problem on pedigree charts.

06-18
11:52

Genomic and cDNA Libraries

A teaching assistant explains how to construct genomic libraries and cDNA libraries.

06-18
04:09

Transcription & Translation

A teaching assistant works through a practice problem on transcription and translation.

06-18
09:43

Lac operon

A teaching assistant explains the lac operon, using props to demonstrate how the lactose metabolism machinery works.

06-18
05:24

Complementation (Part II)

A teaching assistant works through a practice problem on Complementation.

06-18
04:34

Complementation

A teaching assistant explains the concept of complementation using knitting needles and yarn to demonstrate.

06-18
03:20

Explanation of 5' and 3', C terminus, and N terminus

A teaching assistant explains the numbering and labeling conventions of nucleic acids and proteins.

06-18
02:08

Agarose Gel Electrophoresis, DNA Sequencing, PCR, Excerpt 2

Professor Lander continues with the discussion of DNA Sequencing technologies, methods of analyzing DNA sequencing data, and the process of Polymerase Chain Reaction (PCR) and its applications.

06-18
42:27

Agarose Gel Electrophoresis, DNA Sequencing, PCR, Lecture Video Excerpt 1

Professor Lander explains methods of analyzing a gene of interest after it has been cloned.

06-18
17:46

Constructing and Screening a Recombinant DNA Library

Professor Lander reviews the process of constructing a DNA library, and then discusses how to analyze and use the information in the library.

06-18
19:11

Macromolecules: Lipids, Carbohydrates, Nucleic Acid, Excerpt 1

Professor Sive introduces macromolecules, and discusses the structures, properties, and functions of lipids and carbohydrates.

06-18
35:25

Lipids, Carbohydrates, and Nucleic Acids Practice Problem

A teaching assistant goes over a practice problem on lipids, carbohydrates, and nucleic acids.

06-18
08:33

cDNA Libraries and Expression Libraries

Professor Lander uses the human beta globin gene as an example to discuss methods of cloning a human gene in bacterials cells.

06-18
13:31

Covalent Bonds

A teaching assistant goes over a practice problem on covalent bonds, chirality, electronegativity, and hydrogen bonds.

06-18
05:51

Covalent Bonds, Hydrogen Bonds

Professor Walker discusses the chemical forces that are important for the structure and function of biomolecules, and how these properties influence the characteristics of key macromolecules.

06-18
22:24

Biochemical Reactions, Enzymes, and ATP

Professor Sive discusses the chemical reactions within a cell by explaining the rules underlying energy use, how enzymes and catalysts work, and how ATP is used in cells.

06-18
43:36

Photosynthesis

Professor Walker explains the process of photosynthesis, its evolutionary significance, and the structure of chloroplasts.

06-18
17:02

Glycolysis, Respiration, and Fermentation

Professor Walker gives an overview of glycolysis, respiration, and fermentation, and how cells use the energy from these processes.

06-18
42:06

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