Renegade Psych

In this segment, Jenny and I discuss our cases involving first episode of psychosis in menopause, as well as our differential diagnosis for this phenomenon.  While there simply isn't enough research on this specific presentation, it seems to be common sense that trying hormones to alleviate symptoms would be a much safer and possibly more effective alternative to antipsychotics, antidepressants, or even shock therapy.  Knowing that female patients with known severe mental conditions like schizophrenia and bipolar disorder have worsening of their symptoms during transitional periods like menopause indicates a potential role for a hormone therapy trial.  Hope you enjoy. Thanks for listening.  For more social media content, check us out on all social media platforms @Renegadepsych. If you have any comments, questions or challenges to the information we've presented here, if you'd like to be a guest to the show, or if you have general comments, questions, or suggestions, email us at [email protected] and follow the link https://renegade-psych.podcastpage.io/ to our website for source material, transcripts, and additional links for my guests. If you feel passionate about our message and what we're trying to do, and you'd like to donate, you can also follow the link in the show notes to our website. Disclaimer, this podcast is for informational purposes only. The information provided in this podcast and related materials are meant only to educate.  This information is not intended as a substitute for professional medical advice. While I am a medical doctor and many of my guests have extensive medical training and experience, nothing stated in this podcast nor materials related to this podcast, including recommended websites, texts, graphics, images, or any other materials should be treated as a substitute for professional medical or psychological advice, diagnosis or treatment. All listeners should consult with a medical professional, licensed mental health provider or other healthcare provider if seeking medical advice, diagnosis, or treatment.

Here, we each present our closing thoughts on the use of female reproductive hormones during menopause and the phenomenon of menopausal psychosis and/or exacerbation of psychiatric symptoms during female hormonal transitional periods.  Thanks so much to Drs. Wood and Grider for being a part of this, and please stick around after the disclaimer to hear one of my favorite local artists, Jared Foos, who just released his first solo album, titled "Who Loves you Baby," with his hit song, "Leave."  If you or anyone you know is looking to have their music platformed, please send it my way and I'll see if I can work it into the closing thoughts of another series! Thanks for listening.  For more social media content, check us out on all social media platforms @Renegadepsych. If you have any comments, questions or challenges to the information we've presented here, if you'd like to be a guest to the show, or if you have general comments, questions, or suggestions, email us at [email protected] and follow the link https://renegade-psych.podcastpage.io/ to our website for source material, transcripts, and additional links for my guests. If you feel passionate about our message and what we're trying to do, and you'd like to donate, you can also follow the link in the show notes to our website. Disclaimer, this podcast is for informational purposes only. The information provided in this podcast and related materials are meant only to educate.  This information is not intended as a substitute for professional medical advice. While I am a medical doctor and many of my guests have extensive medical training and experience, nothing stated in this podcast nor materials related to this podcast, including recommended websites, texts, graphics, images, or any other materials should be treated as a substitute for professional medical or psychological advice, diagnosis or treatment. All listeners should consult with a medical professional, licensed mental health provider or other healthcare provider if seeking medical advice, diagnosis, or treatment.

Clozapine is one of the first antipsychotics with a unique chemical structure compared to any other antipsychotic.  It is the most effective at treating patients with treatment-resistant schizophrenia, but is severely underutilized despite its efficacy.  It does have a significant side effect profile that needs to be monitored and managed, but can provide relief to patients who have not found relief from other medications.  Today, I bring on Jose Rubio, MD, at Zucker Hillside Hospital, who specializes in treatment-resistant schizophrenia and is an expert on using Clozapine.  He also trained under John Kane, the original MD and researcher who was tasked by the FDA, which was trying to ban Clozapine due to a string of Scandinavian deaths related to a rare side effect, to bring inpatient treatment-resistant schizophrenic patients in the 1970s OFF of clozapine, and came back to the FDA saying that he wasn't able to find effective treatment for the majority of them and petitioned the FDA to reconsider their ban due to Clozapine being so effective.  Clozapine is very cheap and is another example of us prioritizing less effective and more expensive treatments over tried-and-true treatments.  It DOES have a severe side effect of agranulocytosis (along with a couple others), which impairs the person's immune system to fight off infections, so it requires a significant amount of monitoring especially early in the treatment.  But, for the vast majority of patients, Clozapine is not only tolerated, but provides them relief from their symptoms and a chance to live a more normal life.  Hope you enjoy! For more social media content, check us out on all social media platforms @RenegadePsych. If you have any comments, questions or challenges to the information we've presented here, if you'd like to be a guest to the show, or if you have general comments, questions, or suggestions, email us at [email protected] and follow the link https://renegade-psych.podcastpage.io/  to our website for source material, transcripts, and additional links for my guests. If you feel passionate about our message and what we're trying to do, and you'd like to donate, you can also follow the link in the show notes to our website. Disclaimer, this podcast is for informational purposes only. The information provided in this podcast and related materials are meant only to educate.  This information is not intended as a substitute for professional medical advice. While I am a medical doctor and many of my guests have extensive medical training and experience, nothing stated in this podcast nor materials related to this podcast, including recommended websites, texts, graphics, images, or any other materials should be treated as a substitute for professional medical or psychological advice, diagnosis or treatment. All listeners should consult with a medical professional, licensed mental health provider or other healthcare provider if seeking medical advice, diagnosis, or treatment.

This is the introductory episode to our opening series on Antidepressants - Going Backwards with Dr. Ken Gillman.  We'll talk about how 1st line antidepressant medications have become less effective with time, how the diagnostic criteria for depression have been watered down, and reveal how Evidence-Based Medicine can be heavily manipulated.  We'll also give advice on how to best recognize subtypes of depression and treat them accordingly.  Dr. Gillman is an internationally well-known and well-recognized expert on diagnosing biologic depression and using MAOIs, a class of antidepressants widely used in the 1960s and 1970s but rarely used today, and is also one of, if not THE, leading expert on serotonin toxicity (improperly referred to as 'serotonin syndrome' by non-experts) and runs a website called psychotropical.com trying to shed light on these issues, as well as the historical and current problems with psychiatric and medical research. If you're passionate about what we do here at Renegade Psych, we're now on Patreon! If you'd like to support our work, you can! Or not... I'll continue putting out content as long as my other jobs pay the bills.  Other things you can do: liking, commenting, and sharing our posts also go a long way! https://patreon.com/RenegadePsych. Thanks for listening.  For more social media content, check us out on all social media platforms @Renegadepsych. If you have any comments, questions or challenges to the information we've presented here, if you'd like to be a guest to the show, or if you have general comments, questions, or suggestions, email us at [email protected] and follow the link https://renegade-psych.podcastpage.io/ to our website for source material, transcripts, and additional links for my guests. If you feel passionate about our message and what we're trying to do, and you'd like to donate, you can also follow the link in the show notes to our website. Disclaimer, this podcast is for informational purposes only. The information provided in this podcast and related materials are meant only to educate.  This information is not intended as a substitute for professional medical advice. While I am a medical doctor and many of my guests have extensive medical training and experience, nothing stated in this podcast nor materials related to this podcast, including recommended websites, texts, graphics, images, or any other materials should be treated as a substitute for professional medical or psychological advice, diagnosis or treatment. All listeners should consult with a medical professional, licensed mental health provider or other healthcare provider if seeking medical advice, diagnosis, or treatment.

In this segment, Dr. Gillman tells us about his professional background and what makes him an expert on the subjects of depression and their most appropriate treatments. If you're passionate about what we do here at Renegade Psych, we're now on Patreon! If you'd like to support our work, you can! Or not... I'll continue putting out content as long as my other jobs pay the bills.  Other things you can do: liking, commenting, and sharing our posts also go a long way! https://patreon.com/RenegadePsych. Dr. Gillman is an internationally well-known and well-recognized expert on diagnosing biologic depression and using MAOIs, a class of antidepressants widely used in the 1960s and 1970s but rarely used today, and is also one of, if not THE, leading expert on serotonin toxicity (improperly referred to as 'serotonin syndrome' by non-experts) and runs a website called psychotropical.com trying to shed light on these issues, as well as the historical and current problems with psychiatric and medical research.   Thanks for listening.  For more social media content, check us out on all social media platforms @Renegadepsych. If you have any comments, questions or challenges to the information we've presented here, if you'd like to be a guest to the show, or if you have general comments, questions, or suggestions, email us at [email protected] and follow the link https://renegade-psych.podcastpage.io/ to our website for source material, transcripts, and additional links for my guests. If you feel passionate about our message and what we're trying to do, and you'd like to donate, you can also follow the link in the show notes to our website. Disclaimer, this podcast is for informational purposes only. The information provided in this podcast and related materials are meant only to educate.  This information is not intended as a substitute for professional medical advice. While I am a medical doctor and many of my guests have extensive medical training and experience, nothing stated in this podcast nor materials related to this podcast, including recommended websites, texts, graphics, images, or any other materials should be treated as a substitute for professional medical or psychological advice, diagnosis or treatment. All listeners should consult with a medical professional, licensed mental health provider or other healthcare provider if seeking medical advice, diagnosis, or treatment.