Science Will Win

In drug discovery and development, every part of the process matters. Scientists learn from every experiment and every observation. In fact, some of the most cutting-edge advancements in medicine are being dreamed up from findings uncovered in the past.  In this episode, co-hosts Dr. Raven Baxter and Dr. Ronald Gamble dive deep into antibody drug conjugates, a groundbreaking modality that uses targeted antibody engineering to deliver potent chemotherapy directly to cancer-causing cells. They explore the complex ADC creation process and learn how ADCs are changing the standard of care for bladder cancer, from someone with a personal relationship to the disease.Featured Guests:– Renee Barron-Gores, Caregiver– Phoenix Ho, Vice President, Oncology Early Clinical Development, Pfizer– Sharsti Sandall, Executive Director, ADC Biology, Oncology Research Unit, PfizerDive into the episode here:1:16 - Old ideas yield new discoveries3:01 - How do antibody drug conjugates work?5:07 - The origins of ADCs8:36 - ADCs allow for more targeted cancer treatment10:44 - How are ADCs structured?14:16 - How do scientists find the best ADC combinations?18:27 - Developing oncology drugs22:02 - ADCs and bladder cancer24:28 - A caregiver’s perspective on cancer treatment38:12 - Science Will WinSeason 5 of Science Will Win is created by Pfizer and hosted by Dr. Raven Baxter and Dr. Ronald Gamble. It’s produced by Acast Creative Studios.Check out our social media platforms to take a deeper look into the labs and stories we discuss during the episodes: Instagram (@pfizerinc), TikTok (@pfizer) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Protein-protein interactions facilitate numerous bodily processes – everything from the basics of how our muscles contract to the more complex ways cancer can spread through the body. So, what if there was a way to alter some of these interactions? Or even create new ones?In this episode, we’re diving into the fascinating field of molecular glues, a revolutionary modality on the precipice of changing the treatment landscape for certain cancers and potentially other diseases and conditions. Featured Guests:– Joyann Donaldson, Principal Scientist, Synthesis Group Lead, Pfizer– Jennifer LaFontaine, Head of Oncology Medicinal Chemistry, Pfizer– Neal Sach, Research Fellow, Pfizer– Jillian Spangler, Associate Research Fellow, PfizerDive into the episode here:0:50 - A metaphor to explain molecular glues2:36 - How do molecular glues work in the body?5:57 - A new frontier for cancer treatment 13:05 - The history behind molecular glues16:59 - How do scientists design molecular glues?19:05 - A visit to Pfizer’s La Jolla labs32:42 - How can molecular glues change the patient experience?36:42 - Molecular glues beyond cancer treatmentSeason 5 of Science Will Win is created by Pfizer and hosted by Dr. Raven Baxter and Dr. Ronald Gamble. It’s produced by Acast Creative Studios.Check out our social media platforms to take a deeper look into the labs and stories we discuss during the episodes: Instagram (@pfizerinc), TikTok (@pfizer) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The next frontier of medicine is focused on highly targeted drug therapies that could expand the possibilities of individualized patient care. Today, scientists are working on a particular type of molecule that could harness multiple capabilities and treat inflammatory and autoimmune diseases in ways never done before. In this episode, co-hosts Dr. Raven Baxter and Dr. Ronald Gamble explore how the latest advancements in antibody engineering led to multispecific antibodies—powerhouse molecules that can do the jobs of multiple drugs in one. They learn all about what it takes to assemble these antibodies and the impact they could make on patients—with a patient.  Featured Guests:– Emma Guttman, Chair of the Department of Dermatology, Icahn School of Medicine at Mount Sinai– Amanda Lopez, Patient, Texas Ambassador for the National Eczema Association– Laird Bloom, Senior Director of Biomedicine Design, Pfizer– Thomas Wynn, Vice President of Discovery, Inflammation & Immunology, PfizerDive into the episode here:1:12 - A metaphor for multispecific antibodies4:08 - How do multispecific antibodies work?10:39 - The history behind multispecific antibodies16:29 - How are multispecific antibody drugs are made?22:58 - An eczema expert on the potential of multispecific antibodies29:30 - Amanda Lopez's eczema story40:14 - What's next, and closing thoughtsSeason 5 of Science Will Win is created by Pfizer and hosted by Dr. Raven Baxter and Dr. Ronald Gamble. It’s produced by Acast Creative Studios.Check out our social media platforms to take a deeper look into the labs and stories we discuss during the episodes: Instagram (@pfizerinc), TikTok (@pfizer) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Medical advancements don’t just spring up—they happen by building on decades of previous discoveries. Today, one of these advancements might be on the verge of another breakthrough. But what had to happen first for it to exist?In this episode, co-hosts Dr. Raven Baxter and Dr. Ronald Gamble explore how a vaccine candidate for a deadly, once-mysterious bacterial disease came to be. The story takes them from one doctor’s groundbreaking connection in the 70s, all the way to a real lab where vaccines are being developed today.Featured Guests:– Carol Baker, Pediatric Infectious Disease Specialist– Isis Kanevsky, Senior Director, Vaccines, Pfizer– Ksenia Krylova, Senior Director, Vaccines, PfizerDive into the episode here:02:54 - Getting into the problem05:11 - The basics of immunity and vaccine science09:32 - What is a conjugate vaccine?14:44 - Group B Strep: A case study22:23 - Talking to a GBS pioneer31:40 - A trip to the lab43:08 - What's next, and closing thoughtsSeason 5 of Science Will Win is created by Pfizer and hosted by Dr. Raven Baxter and Dr. Ronald Gamble. It’s produced by Acast Creative Studios.Check out our social media platforms to take a deeper look into the labs and stories we discuss during the episodes: Instagram (@pfizerinc), TikTok (@pfizer) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Science Will Win is back for a new season, with new hosts and a new format. Now, science educators Dr. Raven Baxter a molecular biologist otherwise known as Raven, the Science Maven, and Dr. Ronald Gamble, a theoretical astrophysicist at NASA, are teaming up to explore four exciting medical technologies. These technologies are right on the cusp of a potentially groundbreaking moment, either unlocking our ability to tackle new diseases or allowing us to tackle old ones in ways we never could before. This journey takes our hosts through discussions with cutting edge researchers, stories of medical mysteries solved, and tours of real labs that are used every day in the quest to create new medicines. Tune in to the latest four-part season, coming soon! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Over the last five years, the healthcare industry has witnessed an explosive surge in digital health services, revolutionizing the way we access medical care. Patients today are taking charge of their health journey by using different digital tools to stay on top of their preventative screenings, implement dietary and lifestyle changes, access mental health resources, and so much more. In this conversation, patient advocates and industry leaders from Noom, Thrive, and Pfizer, dive into the potential power of artificial intelligence and the anticipated transformation in personalized health plans. They share real-world examples that highlight how digital technologies are helping patients feel empowered and shape the future of healthcare. Through this conversation you heard Lidia Fonseca reference Health Answers by Pfizer. In February 2025, the Pfizer team launched this new platform, powered by generative AI that provides clear, relevant answers to your health & wellness questions and helps you take action for yourself and your loved ones. To learn more, visit healthanswers.pfizer.com.Moderator:Stephanie Agresta, Managing Director, Ascendancy Events Featured experts:-Karin Bilich, Head of Content, Noom -Lidia Fonseca, Chief Digital & Technology Officer, Pfizer -MT Grant, SVP & GM, Thrive for HealthThis episode was recorded live in Austin, TX on Monday, March 10, as part of Pfizer’s takeover of the South by Southwest podcasting lounge.Please fill out our short survey so we can get to know our listeners better: pfizer.com/podcastsurvey Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

While cancer deaths in the United States have declined in recent years, some populations are being left behind—facing complicated challenges to accessing the care they need. Intervening at the earliest stages of disease onset is critical to cancer treatment success and to reducing the risk of recurrence. So how do we create a world where all people with cancer are quickly diagnosed and can live better, longer lives as science advances? In this conversation, patient advocates and healthcare leaders from Pfizer, the American Cancer Society, and the Healthcare Businesswomen’s Association, discuss the power of collaboration in the effort to “Outdo Cancer.”Moderator• Tyrone McClain, Senior Director, Public Affairs, PfizerSpeakers• Carmen White, U.S. & Global Oncology Health Equity Lead, Pfizer• Pam Traxel, American Cancer Society, Cancer Action Network• Mary Stutts, CEO, Healthcare Businesswomen's Association (HBA)This episode was recorded live in Austin, TX on Monday, March 10, as part of Pfizer’s takeover of the South by Southwest podcasting lounge.Please fill out our short survey so we can get to know our listeners better: pfizer.com/podcastsurvey Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Podcasting has become essential for communicating breakthroughs in science, offering an accessible and engaging platform to reach diverse audiences. This evolving medium fosters deeper connections by delivering trusted information in accessible and compelling ways. In this conversation, audio makers from Pfizer, Acast, and TED, discuss what it takes to stand out in the science podcast space, insights on strategy, and how they're working to shape the future of health communication.Moderator• Aaron Strout, Former CMO of Real Chemistry and Health PodcasterSpeakers• Erica Santiago, Executive/Digital Communications & Podcast Strategy, Pfizer• Veronika Taylor, SVP of Acast’s Creator Network• Shoshana Ungerleider MD, Host and Producer of TED Health PodcastThis episode was recorded live in Austin, TX on Monday, March 10, as part of Pfizer’s takeover of the South by Southwest podcasting lounge.Please fill out our short survey so we can get to know our listeners better: pfizer.com/podcastsurvey Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

So far in this season, we’ve explored how innovations throughout history have brought us to where we are now. We talked about how drug discovery changed from a serendipity-based to data-based endeavor. Then, we explored the powerful hardware and smart software required to accommodate big data. Now, the door to the future of AI in drug discovery is open. In our final episode, we’re looking toward the future, to understand where today’s advancements could potentially take us. Featured Guests:–Charlotte Allerton, Head of Preclinical and Translational Sciences at Pfizer–Daniel Ziemek, Vice President of Integrative Biology and Systems Immunology at Pfizer–Enoch Huang, Head of Machine Learning and Computational Sciences at Pfizer–Dr. Raza Ali, group leader at the University of Cambridge Cancer Research UK Institute, pathologist Season 4 of Science Will Win is created by Pfizer and hosted by Jeremiah Owyang, entrepreneur, investor, and tech industry analyst. It’s produced by Wonder Media Network. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

With a trove of data and powerful hardware to process it, software is the last element of our artificial intelligence story. In this episode, host Jeremiah Owyang and expert guests explore the history of advancement behind the software that powers AI today. They delve into the creation of neural networks at the heart of this technology and how scientists are partnering with AI to revolutionize the complex process of drug development and discovery. Featured Guests:–Beth Cimini, Associate Director for Bio image Analysis at the Broad Institute in Cambridge, Massachusetts–Charlotte Allerton, Head of Preclinical and Translational Sciences at Pfizer–Daniel Ziemek, Vice President of Integrative Biology and Systems Immunology at Pfizer–Enoch Huang, Head of Machine Learning and Computational Sciences at Pfizer Season 4 of Science Will Win is created by Pfizer and hosted by Jeremiah Owyang, entrepreneur, investor, and tech industry analyst. It’s produced by Wonder Media Network. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Last episode discussed data and how crucial large swaths of data are in assisting drug development. But more data requires a lot of storage – and that’s where hardware comes in. To make use of big data and all its possibilities, scientists need new tools at their disposal. In this episode, host Jeremiah Owyang, alongside expert guests, traces the rise of large-scale computational resources used throughout the medical industry today.Featured Guests:–Daniel Ziemek, Vice President of Integrative Biology and Systems Immunology at Pfizer–Enoch Huang, Head of Machine Learning and Computational Sciences at Pfizer–Tor Aamodt, professor at the University of British ColumbiaSeason 4 of Science Will Win is created by Pfizer and hosted by Jeremiah Owyang, entrepreneur, investor, and tech industry analyst. It’s produced by Wonder Media Network. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The intersection of biology and technology is revolutionizing drug discovery. In this episode, host Jeremiah Owyang and expert guests explore the crucial role of data in advancing medical science, from the serendipitous discoveries of the past to the cutting-edge techniques of today. They delve into the history of drug development, the rise of "omics," and the innovative single-cell sequencing that is transforming our understanding of the human body for the benefit of drug discovery. Today, scientists are using vast amounts of data to fuel artificial intelligence models, in the quest for new and better medicines. Featured Guests:– James Lowe, Research Fellow at the University of Exeter– Kellie Kravarik, Associate Research Fellow and Cellular Genomics Group Leader for Systems Immunology at Pfizer– Miguel Garcia-Sancho, Lecturer and Researcher at the University of Edinburgh Season 4 of Science Will Win is created by Pfizer and hosted by Jeremiah Owyang, entrepreneur, investor, and tech industry analyst. It’s produced by Wonder Media Network. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Artificial intelligence has the potential to help save millions of lives by accelerating the discovery and development of treatments for humanity’s toughest diseases. Those AI innovations come down to three key factors: data, hardware, and software. Science Will Win Season 4 takes listeners on a journey back in time to learn how each of these three elements got where it is today. Each episode features interviews with historians and cutting-edge researchers, framing these deep historical dives within modern advancements in medical technology. What challenges did science have to overcome to bring us where we are today, the midst of an AI revolution in medicine? Tune in to this new, four-part series, coming soon!Season 4 of Science Will Win is created by Pfizer and hosted by Jeremiah Owyang, entrepreneur, investor, and tech industry analyst. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Throughout history, humans have coalesced around moonshot culture to achieve audacious goals—from eradicating smallpox, to sequencing the human genome, to landing a spacecraft on Mars. These feats of human ingenuity didn’t happen in a vacuum, they were born from intentional innovation, a “coalition of the willing,” and a vision to outdo yesterday. This fireside chat with Drew Panayiotou, Former CMO of Pfizer and Devon Still, ex-NFL player and founder of Still Strong Foundation, explores innovations in cancer, their personal experiences with family members needing healthcare treatment, and what it will take to achieve Pfizer's next big moonshot to outdo cancer and achieve its vision, a world where people with cancer live better and longer lives.This episode was recorded live in Austin, TX on Monday March 11 as part of Pfizer’s takeover of the South by Southwest podcasting lounge. The Let's Outdo Cancer Campaign aims to focus on advances in fighting against cancer. To learn more, visit letsoutdocancer.com. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Podcasting has exploded in the last 5 years, with every celebrity, brand, and influencer investing in audio. It’s estimated that 144MM people in the U.S. listen to a podcast monthly. With scale and an ability to build audience connections, podcasts have become effective at communicating complex information in a digestible way–making them perfect for sharing science-based stories. Many have heard the term "gene therapy," but how many know what it means? How do you explain the science behind artificial intelligence or designing the Mars Rover? Audio allows us to do this, while enhancing the impact of science communications. Join the Pfizer Podcast team, NASA, UT Austin, and Wonder Media Network as they share their audio expertise and accessible approach to scientific storytelling.Featured experts:Shira Atkins, CRO & Co-Founder, Wonder Media NetworkEllen Gerstein, Head Of Digital Communications, Pfizer Inc.Katie Konans, Audio Storytelling Lead, NASAKristen Wynn, Program Manager, The University of Texas at Austin, Dell Medical School, Livestrong Cancer InstitutesThis episode was recorded live in Austin, TX on Monday March 11 as part of Pfizer’s takeover of the South by Southwest podcasting lounge.  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In a live taping of the Science Will Win podcast, Host and Artificial Intelligence Expert Jeremiah Owyang speaks to cutting-edge healthcare leaders about the impact that AI is having on the future of cancer. Thirty years ago, the thought of a world without cancer was nothing more than a dream. Similarly, AI was considered a technology that had yet to become reality. Today, we are reimagining a future where the AI revolution will help change the trajectory of cancer as we know it.Featured experts:Edward Cox, Head & General Manager Of Digital Health & Medicines, PfizerJulie Gerberding, CEO and President, Foundation for the National Institutes of HealthMaimah Karmo, Founder & CEO, Tigerlily FoundationThis episode was recorded live in Austin, TX on Monday March 11 as part of Pfizer’s takeover of the South by Southwest podcasting lounge.  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Is it possible to live in a world without antibiotic resistant bacteria? For the final episode of this season, we’re looking ahead to the future and getting a glimpse of a potential world in which we stay one step ahead of AMR, and what is helping us get there. Host Jeremiah Owyang and expert guests will talk about the education, surveillance, and policy efforts needed for success in the fight against antibiotic resistant bacteria. And we’ll explore how artificial intelligence can empower us in those efforts — and enable more effective, accessible, and equitable healthcare.Featured Guests:Dame Sally Davies, UK Special Envoy for Antimicrobial ResistanceDaniel Gallego, President of the European Kidney Patient FederationRanjit Kumble, Vice President of Enterprise Data Science and Advanced Analytics, PfizerSubha Madhavan, Vice President & Head of AI/ML, Quantitative & Digital Sciences, Global Biometrics & Data ManagementJay Purdy, Vice President and Therapeutic Area Lead, Global Medical Affairs, Pfizer Antibacterial and Antifungal Programs Season 3 of Science Will Win is created by Pfizer and hosted by Jeremiah Owyang, entrepreneur, investor, and tech industry analyst. It’s produced by Wonder Media Network. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Artificial intelligence has the power to transform the way researchers study bacteria and develop new treatments – and we’re already seeing the benefits in healthcare. In part three, host Jeremiah Owyang and expert guests shed light on how AI expedites and enhances analyses, revolutionizing the search for new antibiotics. The benefits of AI extend to analyzing bacterial DNA, uncovering vulnerabilities, and potentially predicting bacterial evolution. This innovative technology aids scientists in pinpointing the most promising antibiotic candidates from a sea of possibilities and helps to streamline drug development.Featured Guests:Adrian Egli, Director, Institute of Medical Microbiology, University of ZurichLei Zhang, Executive Director of Medicinal Chemistry, Pfizer Medicine DesignMarinka Zitnik, Assistant Professor, Department of Biomedical Informatics, Harvard Medical School; Co-founder, Therapeutics Data Commons Season 3 of Science Will Win is created by Pfizer and hosted by Jeremiah Owyang, entrepreneur, investor, and tech industry analyst. It’s produced by Wonder Media Network. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Artificial intelligence could be an essential tool in the fight against antibiotic resistant bacteria – and data is a key part of developing that tool. In part two of this four-part series, expert guests break down the mechanics behind artificial intelligence and machine learning. As host Jeremiah Owyang traces the evolution of these tools in healthcare, he highlights the crucial role of data for understanding the problem of antibiotic resistance. Featured Guests:Adrian Egli, Director, Institute of Medical Microbiology, University of ZurichRanjit Kumble, Vice President of Enterprise Data Science and Advanced Analytics, PfizerMarinka Zitnik, Assistant Professor, Department of Biomedical Informatics, Harvard Medical School; Co-founder, Therapeutics Data Commons Season 3 of Science Will Win is created by Pfizer and hosted by Jeremiah Owyang, entrepreneur, investor, and tech industry analyst. It’s produced by Wonder Media Network. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Medicine’s struggle with antibiotic resistant bacteria is reaching a crisis point. In part one of this four-part series, host Jeremiah Owyang and expert guests delve into the world of antibiotics, exploring their history, the rise of antibiotic resistance, and the story of a patient whose life was forever changed by antibiotic-resistant bacteria. They break down the critical issues at stake and discuss the multifaceted solutions needed to combat this pressing crisis – including artificial intelligence.Featured Guests:Adrian Egli, Director, Institute of Medical Microbiology, University of ZurichJay Purdy, Vice President and Therapeutic Area Lead, Global Medical Affairs, Pfizer Antibacterial and Antifungal ProgramsMary Lynne Van Poelgeest-Pomfret, President, World Federation of Incontinence and Pelvic Problems Season 3 of Science Will Win is created by Pfizer and hosted by Jeremiah Owyang, entrepreneur, investor, and tech industry analyst. It’s produced by Wonder Media Network. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.