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Sigma Nutrition Radio

Author: Danny Lennon

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Discussions about the science of nutrition, dietetics and health. The podcast that educates through nuanced conversations, exploring evidence and cultivating critical thinking. Hosted by Danny Lennon.
392 Episodes
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Prof. Marion Hetherington is Professor of Biopsychology at University of Leeds, where her research is focused on the psychology of appetite across the lifespan. She has previously been at Johns Hopkins, the NIH, the University of Dundee, University of Liverpool and Glasgow Caledonian University, before taking up her role in Leeds in 2008, where she works within the Human Appetite Research Unit. You can find the show notes to this episode at sigmanutrition.com/episode404/ and you can support the podcast at patreon.com/sigmanutrition
Prof. David Jacobs, PhD is Professor of Public Health, in the Division of Epidemiology and Community Health, at the University of Minnesota. He has published highly inflential work in nutritional epidemiology and health epidemiolgy for decades. A number of his papers have brought up crucially important ideas about how to do good nutrition science. Specifically, he has talked about think of whole diet or foods as the exposure of interest, rather than individual nutrients. Essentially warning against the pitfalls of applying a biomedical lens to nutrition research. You can find the show notes to this episode at sigmanutrition.com/episode403/
Prof. Leanne Redman is a Professor of Reproductive Endocrinology & Women’s Health, based at the Pennington Biomedical Research Center. As the director of the Reproductive Endocrinology and Women’s Health Laboratory, she is focused on understanding the intergenerational transmission of obesity. She has published on maternal diet, preeclampsia, and gestational diabetes, amoung other issues. She and her colleagues are currently conducting a rigorous trial to determine the effects of a 6-month gestational intervention with calorie restriction and food provision to promote maternal weight maintenance and fat loss in 100 pregnant women with grades 2 and 3 obesity. Show notes are available at sigmanutrition.com/episode402/ You can support the podcast at patreon.com/sigmanutrition/
We take a look at three more "quacks" who spread misinformation; Dr. Michael Greger (01:21), Eric Berg (36:26), and Dr. Paul Saladino (55:18). We give reference to some specific examples. Show notes available at sigmanutrition.com/episode401/ If you wish to support the podcast you can do so via patreon.com/sigmanutrition/
To celebrate our 400th episode, we take a look at two "quacks" who spread misinformation; Dr. Aseem Malhotra and Dr. James DiNicolantonio. We give reference to some specific examples. Show notes available at https://sigmanutrition.com/episode400/ Subscribe to Danny's free weekly email, the Sigma Synopsis at: https://sigmanutrition.com/synopsis/ Support the podcast on Patreon at: https://www.patreon.com/sigmanutrition
James Betts is Professor of Metabolic Physiology at the University of Bath, where he is Co-Director of the Centre for Nutrition, Exercise & Metabolism. His research employs randomised controlled trials to study the effects of nutrition on metabolic regulation. His group recently published a trial aiming to separate out the effects of fasting from those of calorie restriction. Show notes at sigmanutrition.com/episode399/
Carole Hooven, PhD, is lecturer and codirector of undergraduate studies in the Department of Human Evolutionary Biology at Harvard University. She earned her PhD at Harvard, studying behavioral endocrinology and evolution of sex differences in humans (physiology, behavior and cognition). She has recently written a book on how testosterone influences behaviour and explains many sex differences. The book is titled 'T: The Story of Testosterone, the Hormone that Dominates and Divides Us'. Show notes available at sigmanutrition.com/episode398/
In this episode Danny & Alan discuss the impacts of nitrates and nitrites on health. They look at the beneficial impacts of dietary nitrate, as well as issues around nitrites in processed meat. Show notes available at sigmanutrition.com/episode397/
Dr. Leigh Frame, PhD is Director of Integrative Medicine at George Washington School of Medicine and Health Sciences in Washington DC. Dr. Frame received her PhD in Human Nutrition, as well as a Master of Health Science degree in Molecular Microbiology and Immunology, from the Johns Hopkins Bloomberg School of Public Health. In this episode we discuss a range of topics including: the role of placebo groups and the different types we see in nutrient supplementation trials, potential ethical issues, and the development of research ethics. Show notes available at sigmanutrition.com/epsiode396/
Professor le Roux is an expert in metabolic medicine and is currently a Professor of Experimental Pathology, University College Dublin. He is recognised as a world leader in metabolism and obesity. Professor le Roux’s clinical focus is in the management of Type 2 diabetes, pre-diabetes, obesity, cardiovascular risk and other metabolic disorders. Professor Carel le Roux has been published extensively and currently holds a number of editorial roles for journals in his field including, Clinical Obesity and Surgery for Obesity and Related Diseases. Show notes are available at: sigmanutrition.com/episode395
Gar Benn is the Head of Coaching at Sigma Nutrition, where he works with nutrition coaching clients and oversees the coaching services. He is the owner of CityGym Limerick, a powerlifting-centric gym in Ireland. And he is also the co-founder of the European Powerlifting Confernce and Titan Ireland. Gar is a qualifed nutrition coach and has completed courses in Motivational Interviewing and Acceptance and Commitment Therapy (ACT). Show notes at sigmanutrition.com/episode394/
Vitamin D status is linked to a variety of health outcomes, and avoiding or correcting deficiency is important. However, does supplementing with vitamin D actually benefit most people? Is there evidence for supplementation improving health outcomes like mortality, cancer risk, depression or other outcomes? In this episode Danny and Alan look at intervention trials of vitamin D supplementation. Show notes available at: sigmanutrition.com/episode393/
Dr. Clare Pettinger is a Registered Dietitian, Public Health Nutritionist and experienced educator. Dr. Pettinger publishes research in the public health nutrition field, and lectures at the Universtity of Plymouth, UK.  Dr. Pettinger is actively engaged in community-focussed research around food systems, poverty and social justice. She is an enthusiastic 'sustainability advocate' involved in promoting environmentally sustainable diets for nutrition professionals and Allied Health Professioinals.  Show notes available at sigmanutrition.com/episode392
In this episode Danny and Alan discuss the three primary models used to explain body mass regulation: 1) Set Point Model, 2) Settling Point Model, 3) Dual Intervention Model. They discuss the role of feedback systems, environment, behaviour, as well as discussing both the "thrifty gene hypothesis" and John Speakman's "drifty gene hypothesis".
Gil Carvalho, MD PhD is a medical doctor, research scientist, science communicator. Dr. Carvalho trained as a medical doctor in the University of Lisbon, in his native Portugal, and later obtained a PhD in Biology from Caltech (California Institute of Technology). He has published peer-reviewed medical research spanning the fields of genetics, molecular biology, nutrition, behaviour, aging and neuroscience.   In this episode we discuss: Dairy: is it over-emphasized in the Dietary Guidelines for Americans? Dairy tolerance Critical importance of substitution effects Differences between difference types of dairy on health Claims by some WFPB advocates that olive oil can negatively impact endothethial function Distinguishing between acute and chronic effects Gil's work with Antonio Damasio on feelings Show notes: https://sigmanutrition.com/episode190
Renee McGregor is a leading sports dietitian, specialising in Eating Disorders, REDs, The Female Athlete, athlete health and performance. She is regularly asked to work directly with high performing and professional athletes that have developed a dysfunctional relationship with food that is impacting their performance, health and career. Her practice and knowledge is supported by extensive experience of working in both clinical and performance nutrition, including, Olympic, Paralympic and Commonwealth teams. She is the co-founder and director of #TRAINBRAVE a campaign raising the awareness of eating disorders in sport; providing resources and practical strategies to reduce the prevalence. She is on the REDS advisory board for BASES (The British Association of Sport and Exercise Science) and sits on the International Task Force for Orthorexia. Find the show notes at sigmanutrition.com/episode389
Danny & Alan discuss the current evidence on the health consequences and societal consequences of weight stigma and weigh bias. This includes implicit bias, explicit bias, and internalization of bias. What evidence do we currently have? And what questions remain unanswered? Segments: Today's Topic in Focus [03:39] Listener Questions  [59:48] Quack Asylum [68:55] Random Recommendations [72:07] You can find the show notes to this episode at sigmanutrition.com/episode388 If you wish to support the podcast you can do so on Patreon at patreon.com/sigmanutrition or directly via the site at sigmanutrition.com/donate
#387: Shift Work and Health

#387: Shift Work and Health

2021-05-1801:12:30

In this episode Danny and Alan discuss the relationship between shift work and health. Why does shift work have negative health impacts? How can one mitigate circadian misalignment? How does shift work impact nutrient metabolism? What nutrition, sleep and lifestyle strategies can help shift workers?  Show notes at: sigmanutrition.com/episode387
Dr. Tobias is a nutrition and obesity epidemiologist at the Brigham and Women’s Hospital and Harvard Medical School in Boston, MA. She received doctoral and postdoctoral training from the Harvard TH Chan School of Public Health, Boston, MA, under mentor Dr. Frank B. Hu. Dr. Tobias is co-Instructor of Nutrition Epidemiology with Dr. Walter Willett and faculty member at the Harvard TH Chan School of Public Health. Her epidemiologic research focuses on identifying lifestyle risk factors and underlying mechanisms related to obesity and its major chronic diseases, including type 2 diabetes and cancer. Dr. Tobias is currently the Academic Editor for the American Journal of Clinical Nutrition. Show notes at sigmanutrition.com/episode386
In this episode we explore the causes of insulin resistance, and the dietary modifications that may help those with insulin resistance. We discuss how insulin resistance is a complex metabolic disorder, that goes beyond one single pathway or cause. There is also a discussion on the mechanisms of insulin resistance pathogenesis. Specifically, we talk about the accumulation of ectopic fat. Ectopic fat is the storage of triglycerides in tissues other than fat tissue, such as the liver, skeletal muscle, heart, and pancreas. There is also an overview of the Twin-Cycle Hypothesis, which was discussed in more detail in a previous episode with Prof. Roy Taylor. In addition, we give special mention to liver fat accumulation and the relationship between insulin resistance and non-alcoholic fatty liver disease (NAFLD). Then various diet interventions are assessed for their potential usefulness to those with insulin resistnace. This includes different diet types (e.g. whole-food plant-based diet, low-carbohydrate ketogenic diet, etc.), role of macronutrients, pre-loading studies, and the role of meal timing and circadian effects. Find the show notes at https://sigmanutrition.com/episode385
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Comments (19)

Matt M

A rehash of old episodes

May 13th
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Matt M

Dick

Jan 26th
Reply

ltm

"nutrition lore" 🤣🤣 omg such a descriptive little phrase!

Sep 7th
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ltm

what about choline supplementation for vegan diets, esp during pregnancy??

Jul 25th
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Joern Utermann

really really enjoyed this episode! very interesting topic and cool new format!

Apr 26th
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ltm

very good episode!

Nov 28th
Reply

Mason Verkruisen

assume foods are bad for you until proven innocent is a terrible idea.

Oct 11th
Reply

Shasa Bolton

Great non biased informative discussions with experts in their fields. Thanks for the show

Sep 19th
Reply

justme

Worst podcast EVER. The audio quality is total crap. What a shame

Aug 19th
Reply

Bex G

Brilliant episode, thanks.

Jul 31st
Reply

Aaron Trowbridge

Very interesting debate, thanks for the quality content.

Jan 13th
Reply

Benyamin Asgari

excelent podcast . love it .

Jan 2nd
Reply

Maria Kirby

Another brilliant episode !! I wondered if you would consider doing an episode/discussing how to know what probiotics are recommended for different conditions. I have had my gallbladder removed and suffer with poor digestion and would love to hear more about what I can do to help digestion and possibly what probiotics are recommended for this. Thanks, Maria

Nov 29th
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Matt M

👌🏽

Sep 18th
Reply

Matt M

Great episode 👍🏼

Sep 11th
Reply

ADSK8ER

Love the show!

Jun 8th
Reply

Artin Entezarjou

Great show! We use it to get insight into the evidence for our Instagram page @ebtofficial

May 18th
Reply

Benj

Just found your podcast loving it so far, ATP science is my other favourite but they are also selling products so it is a little bit tainted in that way. your podcast is refreshing because you aren't trying to sell me anything. excepting maybe your guests or sponsors but there's no getting around that. thanks for the hard work love it. p.s. is it possible to have your patreon link in the description on castbox?

May 15th
Reply

Andrew Moore

Very informative and enjoyable!

Mar 5th
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