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Solving the Puzzle with Dr. Datis Kharrazian
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Solving the Puzzle with Dr. Datis Kharrazian

Author: Datis Kharrazian, PhD, DHSc, DC, MS, MMSc, FACN

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Solving the Puzzle with Dr. Datis Kharrazian is based on more than 20 years of Dr. Kharrazian's experience working with autoimmune and brain health patients throughout the U.S. and Europe, exhaustive review of the scientific research, and protocols he has innovated through trial and error in working with complex patient cases.

Dr. Kharrazian discusses evidence-based models incorporating diet, nutrition, and lifestyle — protocols hard won through decades of working with tough, complex patient cases. 


His goal is to help teach you effective models for so-called “mystery” symptoms and conditions so you can regain control of your health and life.


Hashimoto's: Solving the Puzzle, is a new online course from Dr. Kharrazian, who is the originator of evidence-based strategies for managing autoimmune Hashimoto's hypothyroidism. This course has the most complete and current information for managing Hashimoto's available.


You can find more information at drknews.com.

Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.


Hosted on Acast. See acast.com/privacy for more information.

57 Episodes
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In today’s episode, Dr. Christy Sutton breaks down the crucial markers to monitor for iron overload, from classic liver enzymes and iron panels to the often-overlooked cardiovascular and autoimmune risk factors that can clue you into complications before they become serious. You’ll learn about ancillary labs to watch for side effects in the liver, kidneys, brain, hormones, cardiovascular system, and more. Dr. Sutton unpacks the practical nuances of interpreting test results, why “mildly elevated” liver enzymes should never be dismissed, and how overlapping factors like copper, magnesium, and vitamin deficiencies can shape both diagnosis and management. Join Dr. Christy Sutton's 6-hour Kharrazian Institute Master Class on Iron Overload & Undiagnosed Anemias and learn the protocols 90% of practitioners miss.Enroll: pages.kharrazianinstitute.com/sutton-anemiaFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 Hemochromatosis Patient Lab Monitoring04:45 Glutathione Testing and Liver Health06:35 Type 1 Diabetes and Celiac Link12:24 Hemochromatosis and Cardiovascular Risk16:29 Copper and Ceruloplasmin Testing Insights19:49 Copper, Iron, Zinc: Balancing Act24:09 "Solving The Puzzle" Podcast PromoSupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
Anemia affects millions but is often misunderstood or oversimplified. Anemia isn’t just about having low iron. It means you don’t have enough healthy red blood cells or hemoglobin to get vital oxygen to your tissues, organs, and brain. Host Chrissy Sutton breaks down the many different forms of anemia, from iron-deficiency to anemia of inflammation, and even discusses why you can actually have too much iron and still be anemic.We’ll explore how to spot anemia not just with lab work, but by recognizing physical signs like paleness, fatigue, brittle nails, and even changes in your tongue and the whites of your eyes. Dr. Sutton highlights why anemia is more than just feeling tired—it’s tied to everything from exercise intolerance and heart palpitations to developmental delays in children and increased risk for disorders like ADHD.This episode also unpacks the confusing overlap between high ferritin from inflammation versus hemochromatosis, goes in-depth on the impact of pregnancy and menstruation on iron levels, and shares actionable tips for both clinicians and patients. To learn more, enroll in the Master Class “Iron Overload and Undiagnosed Anemias” at https://pages.kharrazianinstitute.com/sutton-anemiaFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 Anemia and Heart Strain Connection10:13 Low Iron Risks in Pregnancy11:40 Early Pregnancy Iron Supplementation18:14 Acid Reducers Impact Iron Levels26:50 Pregnancy: Nutrient Absorption Challenges31:43 "Decoding Iron Deficiency Causes"34:08 Iron Deficiency Anemia Symptoms40:51 Vitamin A Deficiency Risk Factors47:24 "Copper's Role in Iron Regulation"53:34 Diagnosing Hemolytic Anemia54:26 Managing Aplastic Anemia Basics01:01:52 Lead Cabinet Toxicity Solved01:06:09 Ferritin Management Without Blood Removal01:11:14 Digestive Challenges of Low Stomach AcidSupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In this episode, Dr. Kharrazian dives into childhood developmental disorders, with a special focus on dyslexia and processing challenges. Learn why children struggle with reading, writing, or social interaction and how sensory and motor coordination issues are linked to brain development.The conversation breaks down the different types of developmental disorders, from learning and sensory processing to motor skills, psychological health, and communication abilities. Dr. Kharrazian will clarify what dyslexia really is and explore its genetic roots, signs, symptoms, and why early diagnosis is critical. You’ll also hear insights on sensory processing disorders, motor tics, behavioral challenges, and how functional medicine can support children—and adults—facing these challenges by optimizing brain health and development. To dive deeper, enroll in the Kharrazian Institute’s Childhood Developmental Disorders course at https://pages.kharrazianinstitute.com/childhood-development-disorders.For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 Identifying Learning Disorder Pathways05:15 Dyslexia Awareness and Diagnosis Progress15:37 "Dyslexia-Induced Cognitive Fatigue"19:40 Early Dyslexia Impact on Children25:35 Dyslexia: Genetics and Coping Strategies30:01 Dyslexia Screening: Nine Yes Indicators33:17 Supporting Dyslexia: Diagnosis and Brain Health37:23 Factors Impacting Brain Development46:34 Neurorehab: Develop Weak Brain Areas48:17 Sensory and Motor Disorders in Autism54:02 Frontostriatal Pathway and Tics01:00:47 "Understanding PANDAS/PANS in Children"01:08:19 Comprehensive Child Development Disorder Checklist01:09:25 "Pediatric Functional Medicine Overview"01:14:30 Functional Medicine & Nutrition EducationSupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In this episode, Dr. Kharrazian dives into the rising rates and complexities of childhood developmental disorders, such as autism, ADHD, dyslexia, and sensory processing issues, and discusses why so many parents and even healthcare professionals feel overwhelmed or unsupported when it comes to helping these children thrive.Whether you’re a healthcare practitioner, parent, or someone interested in the foundations of healthy brain development, this conversation will give you an understanding of childhood developmental challenges and actionable tools to make a difference. To dive deeper, enroll in the Kharrazian Institute’s Childhood Developmental Disorders course at https://pages.kharrazianinstitute.com/childhood-development-disorders.For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 "Muscle Mass Essential for Longevity"03:05 Sarcopenia Significantly Increases Mortality Risk08:58 Muscle-Gut Axis Influencers: Diet, Hormones, Exercise10:56 Gut-Muscle Axis: Impact on Fitness13:09 Gut-Muscle Connection: Sarcopenia Insights17:33 Muscle Metabolism and Protein Sufficiency20:02 Protein Intake Crucial for Muscle Maintenance25:30 Muscle Issues: Causes and Solutions27:26 Creatine: Muscle Boost and Benefits32:19 Accelerated Muscle Aging Process35:52 Improving Muscle Metabolism with Autophagy38:58 Statins Linked to Muscle Dysfunction40:00 Statin Impact on Muscle Health43:08 Trigger Points and Myofascial Pain48:17 Myofascial Syndromes and Muscle Dysfunction52:52 Functional Medicine Training and ResourcesSupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In this episode, Dr. Datis Kharrazian explains what happens to our muscles as we age and why maintaining muscle mass is crucial for mobility, bone density, cognition, metabolic and immune health, and recovery from chronic illness. You’ll hear actionable insights about sarcopenia (age-related muscle loss), the muscle-gut connection, the power of myokines, and how hormones, nutrition, and strategic exercise can make a life-or-death difference.You’ll hear evidence-based guidance on protein intake, key nutrients, common causes of dysfunctional muscle metabolism, and how to identify and address issues like statin-induced myopathy and abnormal muscle tone.To dive deeper, enroll in the Kharrazian Institute’s Degenerative Joint, Muscle, and Bone Conditions Course.Sign up here: https://pages.kharrazianinstitute.com/ki-bone-jointFor patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 "Muscle Mass Essential for Longevity"03:05 Sarcopenia Significantly Increases Mortality Risk08:58 Muscle-Gut Axis Influencers: Diet, Hormones, Exercise10:56 Gut-Muscle Axis: Impact on Fitness13:09 Gut-Muscle Connection: Sarcopenia Insights17:33 Muscle Metabolism and Protein Sufficiency20:02 Protein Intake Crucial for Muscle Maintenance25:30 Muscle Issues: Causes and Solutions27:26 Creatine: Muscle Boost and Benefits32:19 Accelerated Muscle Aging Process35:52 Improving Muscle Metabolism with Autophagy38:58 Statins Linked to Muscle Dysfunction40:00 Statin Impact on Muscle Health43:08 Trigger Points and Myofascial Pain48:17 Myofascial Syndromes and Muscle Dysfunction52:52 Functional Medicine Training and ResourcesSupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In this episode, you’ll learn how movement directly influences your metabolism, immune system, brain function, and even the diversity of your gut microbiome. Dr. Kharrazian explains the critical role of messenger proteins released during physical activity, why maintaining muscle mass and bone density is key to longevity, and how inflammation can undermine your body’s ability to recover.For patient-oriented functional medicine courses, visit https://drknews.com/online-courses/For practitioner functional medicine certification courses, visit https://kharrazianinstitute.com/For Certified Functional Nutrition education for both practitioners and lay people, visit https://afnlm.com/00:00 Introduction to the Podcast00:30 How Physical Movement Impacts Health01:54 Bone Volume, Osteopenia, and Health Consequences02:56 Toxic Chemicals, Bone Loss, and Aging03:50 Muscle Mass, Sarcopenia, and Mortality04:38 Movement, Depression, and Brain Chemistry05:15 Movement, Myokines, and Immune Function05:59 Microbiome Diversity, Gut Health, and Inactivity06:32 Overtraining Syndrome and its Red Flags07:11 Exercise, Mitochondrial Health, and Chronic Disease07:49 Movement & Brain Health: Repair, Mood, and Cognitive Disorders08:25 Sedentary Lifestyle in Children & Sarcopenia Risks09:45 Medical Management of Osteoporosis and Arthritis10:55 Inflammation, Muscular and Skeletal Degeneration12:16 Body Fat, Skinny Fat, and Inflammation12:46 Insulin Surges and Systemic Inflammation13:31 Microbiome, Leaky Gut, and Chronic Inflammatory Disease16:04 Food, Environmental Toxins, and Inflammation18:09 Protein Intake and Recovery from Chronic Disease19:12 Sleep, Sleep Apnea, and Bone Health19:57 Regenerative Medicine Therapies21:34 Conclusion and Podcast ResourcesSupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
Welcome back to Solving the Puzzle with Dr. Datis Kharrazian, the podcast where evidence-based functional medicine meets real-world application. In this episode, Dr. Joseph Pizzorno, a pioneering voice in environmental medicine and toxicology dives into the hidden world of environmental toxins—discussing the staggering number of chemicals we're exposed to every day, why testing for toxins can be more complex than most realize, and which common exposures may be silently sabotaging our health.Dr. Pizzorno reveals the challenges in accurately measuring toxic load, the wide differences in our bodies’ abilities to detoxify, and why focusing on exposure and biological damage is often more useful than hunting for specific chemicals in the blood or urine. You'll learn about practical strategies for identifying and reducing toxin exposure, the synergistic effects of multiple chemicals, and simple steps you can take to support your body’s natural defenses.Whether you're a clinician wanting clinical pearls or someone seeking to optimize your health in an increasingly toxic world, this episode will empower you with the knowledge and tools to take action.For patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/For patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Assessing Exposure and Detox Challenges03:37 "Assessing Synergistic Environmental Toxins"07:09 "Toxic Load vs. Disease Correlation"11:24 Tea Habits and Water Concentration16:24 Chemical Impact on Neurological Health17:48 Persistent Human-Made Molecules23:20 Bisphenols Lowering Children's IQ26:18 Chemical Food Sources & Glyphosate Exposure28:26 Cerrillini's Impact on Glyphosate Regulation32:50 "Assessing Kidney Toxicity via EGFR"36:44 "Enhancing Body Detoxification"37:42 "Detox Strategy: Sweat and Monitor"Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In this episode, we dive into the environmental and lifestyle factors that impact autoimmunity. From evaluating case reviews to understanding the significance of relationships, stress, and sleep, we explore how these elements shape autoimmune diseases. Discover how proper lifestyle medicine is crucial, and why it’s more than just about supplements. Learn about sleep disorders, chemical exposures, and the role of circadian rhythms in modulating the immune system. For more details, visit drknews.com.For patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Patient Screening and Case Review Process07:55 Sleep's Impact on Immune Function11:27 Rheumatoid Arthritis: Sleep's Vital Role16:15 Stress, Autoimmunity, and IL-17 Dynamics22:13 Exercise & Autoimmunity: Personalized Approach26:57 Chemical Bio-Transformation: Can vs. Can't31:17 Chemical Sensitivity and Immune Response37:45 BPA Study on Autoimmunity Impact44:16 "Identifying Active Heavy Metal Exposure"50:48 Chemical & Immune Tolerance Issues54:42 Avoiding Challenge Tests: Prioritize Immune Reactivity01:01:47 Optimizing Liver Detox and Nutrition01:06:54 Glutathione Protocol for Heavy Metals01:11:03 Glutathione Inhalation for Lung Health01:14:38 Dr. Kharrazian Podcast ResourcesSupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In this episode of "Solving the Puzzle with Dr. Datis Kharrazian," we dive into the intricate world of gastrointestinal health, focusing specifically on the common pathogen Helicobacter pylori (H. pylori) and various parasites affecting the human body. Dr. Kharrazian as explores the pathophysiological mechanisms of these infections, their clinical presentations, and the potential systemic health issues they can trigger, including autoimmune diseases, cardiovascular risks, and gastrointestinal disturbances. Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 H. Pylori Pathogenesis Explained05:45 H. Pylori: Symptoms and Risks11:58 H. Pylori's Broad Health Impact19:24 Urea Breath Test for H. Pylori25:40 Digestive Health Supplement Strategies32:05 Malaria Symptoms and Transmission Overview36:49 Dormant Malaria Parasite Reactivation39:24 Asymptomatic Malaria: Hidden Transmission Risk46:07 Parasite Transmission Via Poor Hygiene51:12 Deworming Benefits for HIV Patients57:24 Mixed Results in Autoimmune Disease Treatment01:04:05 "Chronic Infections and Immune Function"01:06:46 Sleep's Role in Immunity01:14:47 Bile Acids: Key Immune Regulators01:21:25 Mucosal Immunity and Microbiome Health01:22:37 Factors Affecting Microbiome DiversitySupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In today's episode, Dr. Kharrazian interviews Randy Vawdry, NP-C, a respected nurse practitioner who has carved a niche in the realm of functional medicine. With a background ranging from nursing home care to urgent care, Randy brings a wealth of practical experience to our discussion about neurological health and treatment. We dive into his innovative approaches to neurological health, exploring how metabolic health, hormone optimization, and understanding traumatic brain injuries can revolutionize patient care. Randy shares invaluable insights from his clinical practice and educational endeavors, shedding light on how practitioners can master the complexities of brain health to improve outcomes for themselves, their patients, and even their loved ones.SIGN UP HERE: http://pages.kharrazianinstitute.com/vawdrey-neurological-disordersLearn more at kharrazianinstitute.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Master Class with Expert Clinician04:26 Optimizing Neurological Health Priorities06:35 Value of Mastering Functional Medicine10:16 Prioritize Brain Health for Practitioners13:18 Simplifying Complex Concepts17:40 Lifestyle Medicine and Hormone Optimization20:41 Rethinking Functional Medicine Approach24:35 Functional Medicine's Inexperience Problem28:33 "Symptoms Are the Disease"29:17 Lifestyle Choices and Alzheimer's Prevention33:59 "Promoting Continuous Glucose Monitoring"37:19 Master Class on Neurological Care39:27 Podcast Disclaimer and Dr. Kharrazian's DisclosuresSupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
This episode dives into the complex world of chronic infections, with a particular focus on the far-reaching impacts of Lyme disease and mold-related illnesses. We explore the debilitating symptoms of chronic Lyme disease, from severe fatigue and chronic joint pain to the potential for neurological damage and heart complications. Our discussion highlights the often-misunderstood overlap between ongoing infections and autoimmune responses, revealing how mismanagement of Lyme can lead to persistent health challenges. Mold illness and mycotoxins are also discussed.Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Ticks must be removed quickly to prevent Lyme.03:13 Bull's-eye rash indicates Lyme disease; treat immediately.08:29 Chronic Lyme disease severely impacts daily functioning.10:31 Lyme disease disrupts metabolism, causing persistent symptoms.16:05 Infection triggers lasting brain inflammation, causing issues.17:06 Bacteria location influences Lyme disease symptoms severity.20:19 Post Lyme syndrome involves neurological autoimmune issues.25:21 Chronic Lyme impacts include autoimmunity, microbiome issues.29:01 Mold triggers allergies; toxic mold releases mycotoxins.33:14 Sensitivity to mold varies; immune reactions differ.33:54 Common cleaning methods can't completely remove mold.39:37 Mycotoxins influence intestinal permeability and healing.42:48 Mycotoxins trigger immune reactions, affecting mold-sensitive individuals.45:11 Gut dysbiosis is influenced by mycotoxins and immunity.48:42 Mold sensitization can cause lifelong health issues.52:02 Mold spores cause symptoms; mycotoxins affect everyone.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In this episode, Dr. Kharrazian discusses chronic infections and antibiotic resistance. Topics include hidden pathogen reservoirs, the role of biofilms in persistent illnesses, and why future generations may struggle with basic bacterial treatment. Hear about innovative strategies like probiotics, fecal transplants, and natural disruptors combating resistant strains. Discover how maintaining immune health is key to battling evolving bacteria and learn practical tips to protect yourself. Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Bacteria classified by Gram stain, cause illness.07:25 Intestinal permeability leads to severe systemic inflammation.10:58 Systemic inflammation, endotoxemia: barrier breakdown, severe illness.20:21 Mycobacterium tuberculosis can reactivate when immunocompromised.26:06 Biofilms cause 80% of chronic bacterial infections.28:25 Biofilms influence IBS and ulcerative colitis severity.33:04 Biofilms cause persistent infections and antibiotic resistance.38:51 Combine medication and natural medicine for bacterial biofilms.45:30 Genetic predisposition causes recurrent E. coli infections.50:48 Poor hygiene impacts multiple body systems significantly.55:28 Bacteria developed resistance, antibiotics became ineffective.01:05:44 Probiotics with antibiotics reduce post-surgery complications.01:11:30 Antibiotics disrupt crucial short chain fatty acid levels.01:13:13 Use antibiotics, probiotics, and short-chain fatty acids.01:18:06 Candida aids immunity but causes problems if overpopulated.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In this episode Dr. Kharrazian explores the world of chronic infections, such as Epstein-Barr Virus (EBV), Hepatitis C, Covid, and Human Cytomegalovirus (CMV), and their impact on our immune system. He explores how some pathogens hide within our bodies and reemerge when our immunity is compromised.He discusses the latest research linking these infections to autoimmune diseases and even cancer, and emphasizes the importance of enhancing our immune defenses rather than just relying on antiviral treatments. He covers a wide range of topics from the basics of virology, the dynamics of long COVID, and the sobering realities of Hepatitis C and Human Papillomavirus (HPV), to the ripple effects of viral infections on our overall health.Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 MHC proteins activate cells to fight infection.06:16 Long COVID factors: comorbidities, age, severity, inflammation, genetics13:50 Viral infection can trigger chronic inflammatory conditions.17:27 Long COVID linked to persistent antinuclear antibodies.22:53 Autoantibodies may form due to SARS-CoV-2 infection.27:28 Hepatitis B virus vaccine increases MS risk.33:58 Alphaviruses include herpes, 53% exhibit antibodies.39:30 Cytomegalovirus linked to autoimmune diseases, immune manipulation.45:39 Chronic Epstein Barr causes inflammation, cancer risk.52:02 Hepatitis C symptoms: diverse and system-wide impacts.57:33 High treatment costs spark global protests, denials.01:00:33 PCR measures viral load; biomarkers assess liver damage.01:06:08 Identify underlying health issues causing recurring infections.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
This episode explores the world of the immune system's response to pathogens and chronic infections. Dr. Kharrazian discusses the intricate mechanisms pathogens use to evade the immune system, leading to chronic infections and reactivations. He speaks on the impact of immune compromise, genetic factors, and other environmental influences on the severity of infections and autoimmune diseases. He also discusses the pivotal role of protein intake, the formation of antibodies, and the potential link between pathogen-induced inflammation and neurodegenerative diseases.Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Different pathogens have unique effects on health.06:30 Local infection can trigger widespread systemic inflammation.10:32 Chronic infections can reactivate and cause autoimmunity.18:51 Pathogens can lead to Alzheimer's disease development.24:38 Inflam aging causes inflammation and body pain.27:47 Blood contains complement systems, T and B cells, and innate adaptive immunity. Persistent pathogens hide in tissues, evade immune barriers. Chronic infections indicate immune system issues.33:02 Complement proteins indicate pathogenic load in blood.40:40 Importance of proteins in immune system activation.46:00 Genetics impacts response to viral infections.49:28 Weakened immunity can cause severe cytokine storms.55:02 Tick and pathogen invasion into tissues explained.58:53 Micronutrient deficiencies can impact immune compromise significantly.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In this episode, Dr. Datis Kharrazian discusses hormone disorders and their impact on puberty, perimenopause, menopause, and andropause. He discusses the onset of hormone-related issues, such as puberty and perimenopausal transition, and provides evidence-based strategies for addressing menstrual irregularities, hormone imbalances, adrenal function, and more. Dr. Kharrazian also delves into the effects of hormone replacement therapy (HRT), the role of essential fatty acids and seed oils, and the impacts of stress on hormone levels. Additionally, he answers questions on hormone therapy, hormone depletion, and the evaluation of pituitary tumors. Listeners will gain insights into managing hormone-related health conditions and understanding the complexities of the endocrine system.Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Addressing imbalances, electrolyte depletion, and functional medicine.04:42 Underweight PCOS patients need specific health care.07:17 Chart discussed general symptoms, diagnostic steps, treatment.10:32 Analyze protein and fat intake for health.15:30 Weight loss can release stored toxins and hormones.18:29 Steroids and sleep, light, sound sensitivity strategies.20:14 Perimenopausal insomnia and low testosterone concerns addressed.23:31 Podcast content not a substitute for medical advice.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In this episode, Dr. Kharrazian provides insights on growth hormone deficiency, testosterone replacement therapy, strategies for PCOS and infertility, and much more. From discussing the use of growth hormone stimulating peptides to addressing heavy menstrual bleeding and gallbladder issues, this episode offers evidence-based approaches to optimizing endocrine function. Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Gradual use of HRT therapy based on age.08:27 Customized hormone therapy starts with low doses.13:03 Testosterone therapy aids weight loss in men.20:15 Testosterone replacement therapy may benefit men with diabetes.23:10 Testosterone replacement therapy in men is safe.30:20 Men with low testosterone treated with injections.35:05 Managing testosterone levels in men, potential issues.38:09 Dietary and lifestyle strategies impact hormones clinically.48:13 Music therapy, blood sugar, ketogenic diet, sleep issues.52:33 Nutraceuticals impact insulin resistance; fasting benefits.56:09 Women in menopause may experience gallbladder issues.01:03:26 Nutraceutical protocols, insulin signaling, PCOS treatment options.01:10:20 Evaluate hypoglycemia, insulin resistance, and dietary history.01:16:18 Decide on hormone therapy based on risks.01:17:43 Understanding aging and its impact on health.01:22:32 Podcast content not a substitute for medical advice.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In this episode we dive into the intricate web of hormone imbalances, menstrual disorders, and andropause. We explore the impact of estrogen and progesterone imbalances on the menstrual cycle, as well as the role of prostaglandin imbalances in conditions like dysmenorrhea and PMS. We also uncover the complexities of andropause in males and address the various symptoms and treatment options available.Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com00:00 Female and male hormone transition patterns summarized.08:51 BMI impacts endocrine system, genetic factors matter.12:40 Excessive estrogen production causes gynecomastia in men.18:51 Prostaglandins influence menstrual pain and discomfort.26:21 Causes of heavy or light menstrual bleeding.32:24 High DHE and testosterone levels suggest PCOS.33:24 PCOS symptoms can normalize with metabolic control.38:45 PCOS pathophysiology, treatment, and clinical manifestations.45:19 Adrenal glands help manage perimenopausal symptoms.49:33 Hormonal changes in perimenopause cause inflammatory response.59:03 Inflammation and hormones affect women's health.01:03:18 Menopause can worsen underlying health conditions.01:06:44 Adulthood: decline in male function and symptoms.01:13:49 LH levels range indicates potential hormone balance.01:16:27 Free testosterone is crucial, especially as we age.01:25:04 Normal range testosterone, relative hypogonad men, DHT.01:27:26 Male and female hormone disorders patterns explained.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In this episode, Dr. Kharrazian delves into the world of hormone imbalances, microbiome diversity, and the impact of polyphenols and phytoestrogens. He discusses evidence-based strategies for autoimmune disease, brain health issues, and chronic health conditions, and sheds light on the pivotal role of gut health in estrogen metabolism. He also addresses nutraceutical support for insulin resistance and regulating testosterone.  For patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Transitioning off HRT may benefit from modulators.06:05 Flavonoids affect estrogen receptor, 4 key foods.10:05 Healthy microbiome diversity enhances effectiveness of soy products.11:16 Carbs impact conversion of phytoestrogens efficiently.16:29 Gut health crucial for managing estrogen disorders.18:57 Diet, lifestyle, supplements affect microbiome diversity.20:53 Liver pathways detoxifying hormones, potential competition. Nutrients aid hepatic inflammation support.26:51 Essential fatty acids are critical for health.30:29 Prostate glands cause pelvic issues, need support.34:19 Men's testosterone, estrogen testing, insulin resistance, obesity, blood sugar imbalances, hypoglycemia, insulin resistance, dietary guidelines.36:02 Optimize diet to prevent blood sugar crashes.39:41 Review found herbal medicines improve PCOS symptoms.42:41 Aggressive protocol for PCOS using nutraceuticals.47:19 Nutraceuticals may protect serotonin cells, boost testosterone.50:44 Botanicals boost testosterone levels but may vary.53:42 Glial cells switch to pro-inflammatory state. Hormone changes amplify neuroinflammation.56:35 Peptides stimulate hormones, potential for endocrine treatment.58:37 Dr. Kharrazian's podcast and blog information.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In this episode, Dr. Kharrazian provides insight into the impact of obesity on male and female hormone imbalances, infertility, and the body's endocrine system. From the role of adipose tissue to the effects of hormone replacement therapy, this episode explores the complexities of hormone balance and offers evidence-based strategies for managing these crucial aspects of health. Dr. Kharrazian discusses blood glucose management, gut health, and the impact of hormone deficiencies on mitochondrial function and other aspects of physiology.For patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/Learn more at drknews.comTimestamps:00:00 Hormones impact mitochondria, affecting cellular function.09:31 Mitochondrial health affects recovery and signaling pathways.12:00 Hormone replacement may fix mitochondrial dysfunction. Stress affects mitochondria.16:22 Certain genetic factors can increase health risks.25:26 Aromatization causes body fat increase, vicious cycle.31:00 Estrogen drop in women leads to fat tissue.32:52 Steroid use can disrupt endocrine system balance.42:35 Healthy adrenal function is crucial in perimenopause.48:03 Adrenal gland imbalances and stress responses summarized.53:04 Insulin resistance causes blood sugar roller coaster.57:10 Symptom patterns indicating early stages of insulin resistance.01:02:30 Gut bacteria convert chemicals and hormones.01:08:19 Hormone deficiency causes leaky gut, affecting health.01:12:26 Inflammatory diets cause low testosterone levels.01:20:18 Hormones critical for health and disease prevention.01:23:28 Hormone imbalances affect brain recovery and health.01:28:20 For more info visit drknews.com/podcast.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
In today's episode, we dive into the impact of hormone imbalance on overall health. From the critical role of adequate sleep in hormone regulation to the potential effects of environmental chemicals on endocrine function, Dr. Kharrazian shares valuable insights and evidence-based strategies for managing hormone imbalances.For patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/Learn more at drknews.com00:00 Toxic chemicals in everyday products, impacts on health.09:13 Endocrine disrupting chemicals impact female reproductive function.12:57 Endocrine disrupting chemicals impact PCOS in females.18:47 Endocrine disrupting chemicals impact serious health conditions.22:17 Inflammation impacts male testosterone and female infertility.32:18 Aquifers impact water supply with hormones, pharmaceuticals.34:54 Use multiple layers of water filtering systems.43:10 Air pollution impacts cortisol and microbiome health.48:26 Intense exercise is important for hormonal balance.52:57 Low or high body mass affects hormones.58:06 Injections are crucial for male obesity issues.01:03:36 Muscle mass affects health risks in obesity.01:08:32 Suppressed FSH, low TSH, hormone-related issues.01:12:27 Hormones, sleep, and strategies for better rest.01:19:50 Minimum needed protein is 1g/lb body weight.01:24:18 Blood sugar: Hypoglycemia vs insulin resistance management.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.
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Comments (2)

Penny Hughes

sadly enough, I think a lot of people are unaware that they can order their own blood work at an independent lab such as Ulta labs. The savings is incredible. while insurance probably won't cover it it's still super inexpensive, considering it's your health! people will spend $150 out for dinner and drinks..... You can spend that same amount and get a full thyroid panel!

Mar 21st
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Penny Hughes

how can the visuals of this presentation be seen?

Mar 19th
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