Symptomatic: A Medical Mystery Podcast

Nearly half of all Americans suffer from a chronic illness and many struggle for an accurate diagnosis. Welcome to “Symptomatic: A Medical Mystery Podcast,” a brand new podcast from iHeartRadio. Each week, host Lauren Bright Pacheco (Happy Face, Murder in Oregon) unravels the medical mystery of a patient’s baffling symptoms and explores how their lives were turned upside down in search of answers.  From the first signs of trouble, through a swirl of misdirection and failed treatment attempts, to the final relief at a confirmed diagnosis - these are their stories. Listen to the first episode of “Symptomatic: A Medical Mystery Podcast" on October 10th, 2022.See omnystudio.com/listener for privacy information.

Did you know 1 in 8 women will get breast cancer in their lifetime? Join Lauren Bright Pacheco for a special episode from the 2024 ASCO Annual Meeting in Chicago, where she dives into the best collaborative approach to breast cancer diagnoses and care. Medical oncologist, Dr. Nan Chen, and breast cancer surgeon, Dr. Sarah Shubeck share how their teamwork benefits breast cancer treatment.See omnystudio.com/listener for privacy information.

Dr. David Fajgenbaum, once a college quarterback and competitive weightlifter, turned medical researcher, was the picture of health until he became critically ill at the age of 25. After all available treatments failed to keep him out of the ICU, David, with his friend Grant’s help, races to save his own life, repurposing existing drugs to find a cure. * * * * * ******* SPOILER ALERT BELOW ******If you’re looking for information on Castleman disease or if would like to find out more about the work of Grant, David, and the Every Cure team, visit EveryCure.org. See omnystudio.com/listener for privacy information.

Gary Gravina, a skilled carpenter and Marine, was rushed to the ER in 2016 due to severe flu-like symptoms which morphed into a brutal battle with a mysterious disease. Discover how Gary's dire condition would lead him to Dr. David Fajgenbaum and Dr. Grant Mitchell, who had become experts on his rare disease. See how their collaboration not only saved Gary’s life but also significantly impacted the field of medicine. * * * * * ******* SPOILER ALERT BELOW ******If you’re looking for information on Castleman disease or if would like to find out more about the work of Grant, David, and the Every Cure team, visit EveryCure.org. See omnystudio.com/listener for privacy information.

About 1 in 8 men will be diagnosed with prostate cancer during their lifetime. Join Lauren Bright Pacheco at the 2024 ASCO Annual Meeting in Chicago, as she investigates the advancements in prostate cancer care.  Dr. Mohammad Atiq shares ways innovative treatments are paving the way for better outcomes.See omnystudio.com/listener for privacy information.

Nyobie grew up knowing there was something different about her body. As a young woman, she was plagued by unexplained symptoms doctors initially dismissed as part of puberty. But persistent pain and swelling in her arms and legs were just the beginning of her battle. After 19 years of being silenced and misled, Nyobie finally found a life-changing doctor - and diagnosis. *  *  *  *  *  * ****** SPOILER ALERT BELOW ****** If you’re looking for more information on Lupus, you can check out the Lupus Foundation of America by heading to Lupus.org. You can also learn more about Nyobie Gordon-Rick and the work of National Health Educator Leticia Ocaña.See omnystudio.com/listener for privacy information.

As a young teenager, Athena began experiencing pimple-like abscesses in various areas of her body. For years, doctors attributed the painful lesions to poor hygiene, shaming Athena into internalizing and enduring her chronic inflammatory condition in silence. Pushing through pain, embarrassment and self-blame, Athena meets a young doctor who finally gives her hope - and a name - for her disorder. *  *  *  *  *  * ************ SPOILER ALERT BELOW ************ If you’re looking for more information on Hidradenitis Suppurativa, you can check out the Hidradenitis Suppurativa Foundation by heading to HS-Foundation.org. You can also explore Athena Gierbolini’s work with Hope for HS. See omnystudio.com/listener for privacy information.

Zach was your average 11-year-old who loved pizza, sports, and going fishing with his Dad until an incident at a baseball game changed his life forever. As an illness quickly takes hold and wreaks havoc on his body, it’s a race against the clock to figure out what’s happening and save Zach’s life. *  *  *  *  *  * ****** SPOILER ALERT BELOW ****** To find out more information on Sepsis, visit Sepsis.org.See omnystudio.com/listener for privacy information.

Shelby was a freshman in college when she got mono - something that, though draining, is very common in school-age kids. But her mono wasn’t like anything her friends or family had ever seen before. As her condition turns life-threatening, stumped doctors search for answers before it is too late for her or her unborn child.  *  *  *  *  *  * ****** SPOILER ALERT BELOW ****** To find out more information on POTS, visit StandingUpToPOTS.org.See omnystudio.com/listener for privacy information.

Kyle was in the ER for a break or sprain almost every month. The injuries were too frequent & too severe to be written off as Kyle just being an active kid. There was something larger at work here. Doctors found a growth on Kyle’s spine that thrusts him onto a rollercoaster ride trying to find the source of the problem before permanent damage is done.  *  *  *  *  *  * ****** SPOILER ALERT BELOW ****** To find out more information on EDS visit the Ehlers-Danlos Society at ehlers-danlos.com or listen to Dr. Bluestein’s podcast - Bendy Bodies with the Hypermobility MD - wherever you get your podcasts.See omnystudio.com/listener for privacy information.

Diagnosed at a young age, Antoinette has dealt with Sickle Cell all her life. It’s not until she’s older that she realizes her Sickle Cell is unlike any case her doctor has seen before. With deliberating symptoms and multiple crises, Antoinette turns to her doctor for a life changing diagnosis.   *  *  *  *  *  * ****** SPOILER ALERT BELOW ****** To find out more information on Sickle Cell disease visit the Sickle Cell Disease Association of America at sicklecelldisease.org.See omnystudio.com/listener for privacy information.

Kam is rapidly losing her motor skills as she’s attacked by an unknown & unseen disease. In a matter of months, she goes from starring on her high school soccer team to struggling to make it up the stairs. Bouncing between doctors and facing countless misdiagnoses, Kam never wavers in her chase to uncover what is threatening to take away her mobility.  *  *  *  *  *  * ****** SPOILER ALERT BELOW ****** For more information on GNE Myopathy go to CureGNEM.org and check out the first ever GNE myopathy clinic at UC Irvine’s neuromuscular center led by one of Dr. Korb’s colleagues. You can also find Kam Redlawsk on Instagram & Twitter @KamRedlawsk. See omnystudio.com/listener for privacy information.

Suffering from inexplicable sores & excruciating pain since he was 5 years old, August searched to uncover what plagued so many years of his life and threatened his mobility.  His dreams of a musical theater career quickly faded away as his condition worsened, so August decided to challenge the constant silencing of his symptoms and fight the cause of the irreversible physical damage. *  *  *  *  *  * ****** SPOILER ALERT BELOW ****** If you’re looking for more information on Behcet’s, you can check out the American Behcet’s Disease Association by heading to www.behcets.com. You can also find August Rocha on Instagram & TikTok @WithLoveAugust.See omnystudio.com/listener for privacy information.

Join Lauren Bright Pacheco for an all-new season of “Symptomatic” starting Tuesday, October 3rd.See omnystudio.com/listener for privacy information.

After the birth of her first child, Michele was hit with the onset of sporadic tingling and numbness on alternating sides of her face. Despite enduring years of the mysterious symptoms, she had given up hope of finding the root cause. Michele eventually built up walls of shame because of the uncontrollable flare-ups. It was the concern of her family and the unwavering support of her new partner that would reignite her hunt for a proper diagnosis.See omnystudio.com/listener for privacy information.

Suffering from incessant fevers, muscle pain, and mysterious nodules across his body for nine years, Chuck's hope was fading. No doctor could explain his sporadic flu-like symptoms. Then, he crossed paths with Dr. Daniel Kastner, an unconventional and brilliant physician with a unique approach to disease research. Together with his colleagues at the National Institutes of Health, their groundbreaking discovery might just hold the key to Chuck's medical mystery. *  *  *  *  *  * ****** SPOILER ALERT BELOW ****** If you’re looking for more information on VEXAS and to learn about Dr. Kastner's work, go to the National Institutes of Health's website at NIH.gov. See omnystudio.com/listener for privacy information.

Jerad had been battling an overwhelming amount of stress while juggling PhD studies, early parenthood, and work with the Minnesota Judicial System. Slowly losing his energy and ability to make it through day-to-day activities, he knew his developing condition meant something even bigger than just stress at work. With his wife’s fierce advocacy, Jerad hurried to find the source of his symptoms before permanent damage was done. *  *  *  *  *  * ****** SPOILER ALERT BELOW ****** If you’d like to follow Jerad Green's story you can find him on Instagram @HeartFailureHotTakes.See omnystudio.com/listener for privacy information.

After going through a challenging divorce and relocating cross country, Chris was struggling with depression and anxiety. For a while, he simply ignored his GI symptoms as they progressively got worse. His bowel issues were soon preventing him from living the life he loved: hiking, attending concerts, and participating in activities with his kids. The situation deteriorated to the point where he had to be rushed to the ER multiple times, sure he was having a heart attack. However, the reality was far more complex. *  *  *  *  *  * ****** SPOILER ALERT BELOW ****** To find out more about Alpha-gal syndrome, you can check out the CDC’s website at CDC.gov or check out AlphaGalInformation.org. See omnystudio.com/listener for privacy information.

In this bonus segment, host Lauren Bright Pacheco checks in with Michele from Case #09 to share feedback from the Symptomatic community.See omnystudio.com/listener for privacy information.

At just 7 years old, Alisha was diagnosed with plaque psoriasis - a condition that manifested in overwhelming flare-ups, covering nearly 90% of her body. Enduring both the physical toll and the harsh judgment of ignorant peers and their parents, she became so self-conscious about showing her skin. She would wear long sleeves in the middle of summer, would never go to the beach, and even feared she would never again be able to feel rain on her skin again. Alisha goes on a long, desperate journey to find a treatment for this disease, seeking not only physical relief but also respite from the mental and emotional trauma of living with psoriasis. *  *  *  *  *  * ****** SPOILER ALERT BELOW ****** If you’re looking for more information on plaque psoriasis, go to the National Psoriasis Foundation’s website at Psoriasis.org. You can also learn more through the Global Healthy Living Foundation at GHLF.org and follow Alisha Bridges on Instagram @AlishaMBridges.See omnystudio.com/listener for privacy information.