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tay up-to-date with the latest research in medicine and science with TT HealthWatch. This 10-minute podcast is hosted by Richard Lange, M.D., M.B.A., president of Texas Tech University Health Sciences Center El Paso and dean of the Paul L. Foster School of Medicine, and Elizabeth Tracey, M.S., Baltimore-based medical journalist.
Each week, Richard and Elizabeth explore recent peer-reviewed studies and breaking medical news, offering a Texas Tech perspective on the latest developments in health care.
41 Episodes
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Program notes:0:40 IVF clinics and private equity1:40 Provide over 54% of all IVF cycles in U.S.2:41 Perhaps a more positive result3:30 EKGs and liver cirrhosis4:30 New diagnosis of advanced liver disease5:30 Most physicians didn't follow up6:18 Management of acute back pain7:18 Did it improve pain or disability?8:18 Four- to eight-hour-long sessions to teach8:46 Lay health worker led intervention for older adults with cancer9:46 Reviewed with advanced practice practitioners10:46 Huge benefit from modest intervention11:46 Pick up the phone and ask12:20 Modest outlay13:09 End
Program notes:0:40 Saturated fat and CVD1:40 When it was reduced in diet only helped in those with high risk2:40 Obesity, diabetes and metabolic syndrome also important3:30 Diagnostic follow up after lung CT4:30 Less intensive than recommended in non-Hispanic blacks5:31 Herpes antiviral and Alzheimer's6:30 Followed for five years7:30 80-90% of population exposed8:30 Change screening criteria for lung ca9:33 Population based study10:30 Calculating pack years11:20 Rolling out through national organizations12:17 End
Program notes:0:37 Breast density knowledge outcomes1:37 Breast density notification and education2:37 Can't assess the import individually3:30 CV outcomes with tirzepatide4:30 HbA1c 8.45:30 GLP-1s have many benefits6:30 No difference in adverse events7:10 Covid vaccination in pregnancy8:10 20K women included9:10 Initial benefit is it durable?9:30 Complex regional pain syndrome treatment10:30 Using bisphosphonates for treatment11:33 Even light contact causes severe pain12:28 End
Program notes:0:35 Should surgery efficacy1:30 10-year follow of ASD surgery2:30 Exercise does relieve pain3:00 Association of pain with intrinsic capacity and inflammation4:00 Domains including locomotion and others5:01 Pain impacts a number of capacities6:01 Aspirational to figure out pain6:30 Scheduling birth at term to avoid preeclampsia7:30 High-risk pregnancy delivered at term8:35 Is there impact on the infants?9:18 AI decision support for large-vessel stroke10:20 71,000+ patients with ischemic stroke11:25 U.S. data also not impressive12:54 End
Program notes:0:35 Update on RSV, flu and COVID-19 vaccines1:35 500 studies included2:35 Rare myocarditis3:35 Flu vaccine in older adults4:30 Tai chi or CBT-I for chronic insomnia5:30 Trained in one or the other6:30 Inexpensive and accessible7:30 $150 billion cost of chronic insomnia7:45 GLP-1s and WHO guidance8:50 Multimodal approach required9:45 Prevention is important9:55 Corticosteroids in pregnancy10:50 1.3 million pregnancies11:50 Used for multiple indications12:46 End
Program notes:0:40 CVD risk factors and texting1:40 How many undergo screening?2:41 Impact of personalized messaging3:25 Decentralized trials versus centralized 4:25 Decentralized much larger5:25 Does the trial move in one way or another?6:15 Two studies related to use of peripregnancy GLP-1 use7:15 Stopping at pregnancy8:15 Is overweight worse than stopping?9:00 Machine learning model, tissues, genetics and age10:00 Practical for assessing genetic basis11:00 Sequential tissue samples11:57 End
Program notes:1:25 mRNA flu vaccine2:25 Phase three trial3:25 Preventing infection with a respiratory virus4:25 Prophylaxis with NSAID?4:45 Umbrella review of acetaminophen in pregnancy, ASD and ADHD5:42 Confidence was low to critically low6:45 Other factors such as environmental exposures7:22 Increasing potassium to prevent heart arrythmias8:33 Increase with supplements or dietary advice9:18 Canceling funding for clinical trials10:18 In the process of receiving interventions11:18 Can't not analyze 12:15 End
Program notes:0:50 Fish oil supplements and hemodialysis1:50 1200 individuals to fish oil or not2:50 Needs another study3:11 PCSK9 inhibitor in people without MI or stroke4:13 3- or 4-point MACE5:11 Getting LDL down helps6:11 Addition of more than one oral agent6:50 Right therapy for afib and a stent7:50 Noninferiority trial8:50 After 12 months single agent works9:27 Anticoagulation after afib tx10:30 Low primary safety outcomes11:25 96% won't have a stroke12:16 End
Program notes:0:37 An oral med for obesity1:37 Five to 10% stopped medication2:35 Need head-to-head trials with injectable3:00 Stem cell infusion after MI and heart failure4:01 Reduced heart failure in recipients5:01 Twice as many in the control arm6:01 Moving past BMI in predicting atherosclerosis7:01 Especially in overweight but not obese8:01 Almost 3000 participants in Brazil8:25 Blood samples precede MS9:04 Seen seven years beforehand10:02 Twin studies and relatives11:03 Way to intervene earlier11:15 Applaud OpenAI13:00 End
Program notes:0:45 Steps, more and longer?1:45 8,000 steps or less2:45 Nothing on intensity3:30 Mediterranean diet for IBS4:30 Reduction in IBS symptom severity scale5:30 Easy to accommodate with high compliance6:30 Exercise for knee osteoarthritis7:30 All types of exercise examined8:30 Initiated exercise to try to address9:00 AI intervention in prediabetes10:00 Based on diabetes prevention program11:00 AI and human led essentially the same12:00 99% of eligible group don't have access13:09 End
Program notes:0:40 Nicotine reduction for various subgroups1:40 Native American and Alaskan populations benefit most2:42 Black, rural populations 10 million lives saved3:40 19-39 million life years saved4:00 Food insecurity and blood pressure5:00 Food vouchers most successful6:00 May be more involved and motivated6:35 PFAS and infant brain architecture7:35 Children assessed with MRI8:30 Didn't correct for various factors9:31 Other types of plasticized chemicals9:50 Afib after cardiac surgery10:50 Only found with implantable monitor11:50 Very short duration of afib12:51 End
Program notes:0:40 New drug for SLE1:41 Monitored for a year2:43 Only one pathway limited3:00 AI and health care4:00 How to assure compliance?5:00 Policy changes needed6:01 Pessimistic about oversight6:50 Genetic treatment for ADA deficiency7:50 Using a viral vector8:50 A curative treatment9:30 Social media and cognitive performance in adolescents10:30 Low and high increasing social media use11:30 Good enough evidence12:31 End
Program notes:0:40 Aldosterone as a risk factor for heart disease1:40 Spectrum of renin-aldosterone levels2:40 As many as 25-30% may have3:11 All pharmacologic interventions for obesity tx4:14 All effective compared with placebo5:12 Meta-analysis 6:13 Very little data in overweight or massively obese6:35 Where do U.S. antibiotics come from?7:35 India leading country for finished product8:20 Environmental impact of inhalers9:20 Annual emissions increased by 24%10:23 Decreased by 43%11:23 Three forms of inhaler12:40 End
Program notes:1:21 Bronchiectasis treatment2:22 Twenty sites in UK3:20 Medical imaging and cancer risk in kids4:20 3000 hematologic cancers5:20 Consider other types of imaging6:23 Head CT increases risk by 35%7:24 Treating pulmonary arterial hypertension8:24 Improved mortality in another trial9:25 Antibody prevention of RSV in healthy infants10:25 Healthy preterm and full term infants11:25 Argues for use of this antibody globally12:25 Antibodies against antibody didn't compromise13:08 End
Program notes:0:40 Private equity takeover of hospitals1:40 Reduced salaries or staffing2:40 Patients likely to cost system3:30 Use of anti thymocyte globulin to slow down T1D in youth4:30 Diagnosed within 9 weeks prior5:30 Serum sickness in 82% of highest dose group6:30 Incidence increasing by 2% per year over 20 years7:00 Aspirin in CRC8:00 1100 patients with mutation9:00 Can this mutation be acquired?9:15 Alcohol and dementia10:15 Confounding factors relative to alcohol use11:15 Is there a safe level of consumption?12:40 End
Program notes:0:45 Intimate partner violence and CVD1:45 12% reported stalking2:46 Screening in primary care3:47 Fifty to 200% increased risk4:00 Number of psychiatric disorders and dementia risk5:00 Important to be aware when mental health disorders exist6:03 Anxiety and depression associated6:33 Lipoprotein(a) and widespread vascular disease7:31 High risk of extracoronary vascular disease8:32 Also associated with complications9:32 Unknown why some areas affected10:00 Second cancers after early invasive breast cancer11:00 Contralateral breast cancer greater in younger women12:00 Not excessive risk13:31 End
Program notes:0:45 LSD and treatment of generalized anxiety disorders1:45 Change in anxiety score to 12 weeks post administration2:45 100 micrograms appear most efficacious3:45 Require inpatient 12 hours4:44 Cardiac rehab in older patients after MI5:44 Frail individuals can improve outcome6:45 Oftentimes think it won't make a difference7:10 CT and pregnancy outcomes8:10 Linear relationship with increasing CT scans9:10 Closer to conception more likely 10:10 Sometimes not really necessary10:21 New tx for resistant hypertension11:20 Baxdrostat inhibits aldosterone12:20 What happens when aldosterone drops13:07 End
Program notes:0:53 Who needs a beta blocker after MI1:53 Those with mild reduction of ejection fraction2:53 Confined to those with 40-50% ejection fraction3:15 Revascularization in NSTEMI4:20 Composite outcome5:20 Closes gap, do FFR6:20 May not be physiologically significant6:40 Is lifelong anticoagulation needed after ablation7:41 Occurred less in those who stopped8:30 RSV, cardiac events and hospitalizations9:30 Lower hospitalization in those who got the vaccine10:30 Acute respiratory illness hospitalization11:30 Less benefit with existing CVD or immunocompromise12:15 Several RSV vaccines13:16 End
Program notes:0:44 Drug prices around the world1:41 German prices as standard2:40 Wide variation in price and affordability3:40 Generic pricing 4:20 ADHD meds and behavior choices5:20 Largely treated with methylphenidate6:20 Significantly impacted suicidality and other behaviors6:49 AI assistance and colonoscopy skills7:49 When you stop AI assistance8:50 Does this apply to other procedures that use AI9:20 Trauma predictive brain networks10:20 Use of hydrocortisone to damp down11:20 Previous trauma impact12:25 Developmental timing13:30 End
Program Notes:0:44 Spuds are what we call potatoes1:47 Followed for over 5million person years2:45 No mechanism for why french fries are problematic3:25 DASH4D diet for glycemic control4:25 4 diets compared 5:25 Extends benefits outside hypertension6:20 A new antibiotic for staph infections7:20 IV therapy until cultures are negative8:20 Cost of new therapy, cost effectiveness8:40 Geographic variation in subspeciality cancer care9:40 Highest income managed by specialists10:40 Guidelines expanded11:36 Telemedicine may help12:10 End
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