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The End Game

Author: Melissa Butterworth

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The End Game: Laboratory Insiders on Your Side is a  podcast by senior lab executives for senior lab executives. This podcast shares valuable industry knowledge, tips, and strategies that when applied and properly executed will help lab executives succeed, thrive, and ultimately become better prepared for their own End Game.

46 Episodes
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In this episode of the End Game Podcast, host Melissa Butterworth discusses the recent transaction between Community Health Systems (CHS) and LabCorp, highlighting its significance for patient care and the healthcare industry. She provides insights into the operational aspects of the deal, the impact on lab services, and the ongoing trend of hospital divestitures in the lab sector. Melissa emphasizes the positive outcomes for patients and the strategic importance of such transactions in enhan...
Host Melissa Butterworth, founder of Advanced Strategic Partners and seasoned lab executive, is back for part two of her deep dive into the fast-growing world of direct-to-consumer testing. In this episode, Melissa shares 10 lesser-known at-home health tests that could uncover hidden health issues—from food sensitivities and heavy metals to biological aging and even HPV. Drawing from personal experience and industry insight, she highlights which tests are worth trying, where to find them, and...
In this conversation, Melissa Butterworth discusses the rise of direct-to-consumer testing, emphasizing how it empowers patients to take control of their health. She likens the market to Netflix, highlighting its convenience and personalization.
In this special solo episode of End Game: Insiders on Your Side, host Melissa Butterworth takes listeners behind the scenes of her own career journey—from pharmaceutical sales to leading one of the nation’s top M&A firms for laboratories. With her extensive background in sales, Melissa dives deep into the many sales and business development opportunities within the laboratory diagnostic industry. From entry-level diagnostic sales representatives to high-stakes strategic account executives...
In this episode, Melissa Butterworth discusses the current state and future of the clinical laboratory industry, highlighting its significance in medical decision-making, the types of labs, and the impact of technology and consolidation on the market.
In this episode of the Endgame podcast, Melissa Butterworth discusses the transformative impact of AI on the laboratory diagnostic industry. She explores how AI enhances diagnostic precision, streamlines workflows, and supports personalized medicine. The conversation highlights the significant growth of AI in pathology and its potential to revolutionize lab operations, making them more efficient and effective. Melissa emphasizes the urgency for labs to embrace AI technology to stay competitiv...
In this inspiring episode of The End Game: Insiders on Your Side, host Melissa Butterworth sits down with Ravi Pulugurtha, Vice President of Operations at G3 Vision Labs, to explore the bold vision of delivering better healthcare everywhere for everyone. Ravi shares his journey from leading roles in healthcare technology to his current mission of transforming diagnostics—making them faster, more accessible, and patient-centric. He discusses how COVID-19 exposed the urgent need for timely test...
How can artificial intelligence turn lab data into life-changing patient outcomes? In this episode of The End Game Insiders podcast, host Melissa Butterworth sits down with Brad Bostic, CEO of HC1, to explore how AI-powered healthcare analytics is reshaping the way we deliver care. From optimizing lab operations to driving value-based care, Brad shares how AI can: Personalize patient care through lab-driven insightsIdentify care gaps before they become crisesImprove operational efficiency and...
Join host Melissa Butterworth on "The End Game" as she explores the dynamic landscape of hospital systems and their strategic decisions to divest outreach programs. In this episode, Melissa discusses the financial, operational, and regulatory challenges prompting hospitals to reconsider their involvement in laboratory diagnostics. Learn about the significant transactions reshaping the industry. Tune in for an in-depth analysis of the healthcare market and its evolving priorities.
In this episode, host Melissa Butterworth sits down with Matt Honan, Vice President of Business Development at Sonic Healthcare, to explore why more and more health systems are choosing to monetize their lab outreach programs, enter management arrangements, and seek strategic partners. Together, they unpack what successful relationships between health systems and commercial labs really look like—from cultural alignment to long-term strategic value. Matt shares his insights into how buyer...
In this episode of The End Game podcast, host Melissa Butterworth interviews Ravi Pulagurtha, Vice President of G3 Vision Labs. They discuss the vision for better healthcare for everyone, the importance of timely diagnostics, and how G3 Vision Labs is redefining trust in medical testing. Ravi shares insights on the innovative steps the lab is taking to improve patient access and care, while maintaining integrity and values during growth. The conversation highlights the role of technology and ...
In this episode, Melissa Butterworth discusses the importance of not accepting direct offers for lab sales without going through a comprehensive six-step M&A process. She emphasizes the need for lab owners to evaluate their offers in the market to maximize their lab's value. Drawing from her personal experience as a lab owner, she shares insights on how competition can lead to better offers and encourages listeners to reach out for more information on the M&A process.
In this episode of the Endgame podcast, Melissa Butterworth discusses the key factors that influence the valuation of laboratories when they are taken to market. She emphasizes the importance of understanding the type of buyer, the impact of revenue compression, and the significance of lab type and location. The conversation provides insights into why lab owners should consider multiple offers and the dynamics of the healthcare market.
In this episode, Melissa Butterworth discusses the founding of Advanced Strategic Partners, highlighting her extensive experience in the laboratory industry and the unique differentiators of her firm. She elaborates on the services offered, including valuation and operational assessments, and emphasizes the importance of insider connections in maximizing laboratory value.
In this episode of The End Game podcast, host Melissa Butterworth speaks with John David Klipp about the evolving landscape of hospital outreach transactions. They discuss the recent surge in hospital systems considering divestment of their lab operations due to financial pressures, the perspectives of hospital executives, and the challenges faced in understanding the true value of laboratory assets. The conversation also touches on the concerns of pathologists regarding potential changes in ...
In the latest episode of The End Game Podcast, host Melissa Butterworth takes a deep dive into the evolving M&A landscape for laboratories as we head into 2025. From the rise of larger transactions to the types of acquisitions shaping the industry, Melissa breaks down the key trends lab owners need to know. She also shares insights from her published works, offering practical strategies to help lab owners successfully navigate the M&A process and maximize their outcomes. Whether you'r...
In this episode of The End Game, Melissa Butterworth explores the critical role of timing in laboratory sales. She shares a real-life case study that illustrates how market decisions can significantly impact financial outcomes. Melissa emphasizes the importance of working with specialized M&A advisory firms to navigate the complexities of the industry and ensure lab executives maximize their organization's value.
In the latest episode of The End Game, Melissa Butterworth sits down with attorney Jane Pine wood to unpack the critical legal and compliance issues facing pathology practices and laboratories. From billing due diligence to sales and marketing regulations, licensure complexities, and payer contracts—Jane shares expert insights on how to avoid costly missteps that could devalue a practice. Transparency during transactions is key, and having the right legal counsel can make all the difference i...
In this episode of the End Game Insiders podcast, Melissa Butterworth interviews Adam Earl, a former lab owner who shares his experiences navigating the M&A process in the lab industry. Adam discusses his journey from entering the lab business to successfully selling his lab amidst the challenges posed by the COVID-19 pandemic. He emphasizes the importance of building strong customer relationships, the role of investment bankers, and the lessons learned throughout the M&A process. Ada...
Learn from the best with this HFMA webinar! This episode goes over the current hospital laboratory market and gain insight on: Understand current market dynamics and what they mean for your organizationDevelop an effective approach to determine the best going forward model for your lab operationsUnderstand the components and time frame of a transactionGain insight into the key transaction business, operational and legal issues
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