The Hematologist

The Hematologist is the member newsletter of American Society of Hematology (ASH). It is designed for the broad constituency of ASH, all working toward the ultimate goal of conquering blood diseases. The Hematologist updates readers about important developments in the field of hematology and highlights what ASH is doing for its members.

DREAMMing of a Better Tomorrow: Belantamab-Based Triplet Therapy for Relapsed/Refractory Multiple Myeloma

In this episode, Contributing Editor Ajai Chari, MD, a professor of clinical medicine and director of the myeloma program at the University of California San Francisco, talks with Meletios Dimopoulos, MD, a professor and chair of the Department of Clinical Therapeutics at the National and Kopodistrian University of Athens School of Medicine in Athens, Greece. They talk about a recent paper co-authored by Dr. Dimopoulos: “Belantamab Mafodotin, Pomalidomide (PA), and Dexamethasone in Multiple Myeloma.” 

12-21
18:56

Haploidentical Stem Cell Transplantation Is an Acceptable Transformative Therapy for Young Adults With Sickle Cell Disease

In this episode, Contributing Editor Samuel Wilson, MD, an assistant professor of hematology at the University of North Carolina Chapel Hill, talks with Adetola Kassim, MD, a professor of medicine in the division of hematology and oncology at Vanderbilt University Medical Center. They talk about a recent paper co-authored by Dr. Kassim: “An International Learning Collaborative Phase 2 Trial for Haploidentical Bone Marrow Transplant in Sickle Cell Disease.”

11-27
23:43

Enhancing Risk Stratification for Pediatric B-Cell Acute Lymphoblastic Leukemia: No Longer a ‘PI’ in the Sky Idea?

In this episode, Contributing Editor Lauren Pommert, MD, a pediatric oncologist specializing in children with leukemia at Cincinnati Children's in Cincinnati, Ohio, talks with Natalie DelRocco, PhD, a senior statistician for the Children’s Oncology Group’s Bone Tumors Committee and an assistant professor of clinical population and public health sciences in the Division of Biostatistics at the University of Southern California in Los Angeles. They talk about a recent paper co-authored by Dr. DelRocco: “Enhanced Risk Stratification for Children and Young Adults With B-Cell Acute Lymphoblastic Leukemia: A Children’s Oncology Group Report.”

10-11
18:11

A Leap of Faith? Elimination of Autologous Stem Cell Transplantation for Patients With Mantle Cell Lymphoma in First Remission

In this episode, Contributing Editor Tycel Phillips, MD, an associate professor of medicine and a hematologist-oncologist at City of Hope Medical Center in Duarte, California, talks with Martin Dreyling, MD, a professor of medicine and head of the lymphoma program at LMU Hospital in Munich. They discuss the TRIANGLE trial, conducted by Dr. Dreyling and colleagues, for the European Mantle Cell Lymphoma Network. 

09-16
21:39

Anticoagulation Stewardship

In this episode, Contributing Editor Surbhi Shah, MD, a classical hematologist at Mayo Clinic in Phoenix, leads a conversation about anticoagulation stewardship. Her guests are Allison Burnett, PharmD, PhC, an antithrombosis stewardship pharmacist at the University of New Mexico Hospital and president of the Anticoagulation Forum, and Geoffrey Barnes, MD, MSc, an associate professor and vascular medicine specialist at the University of Michigan and president-elect of the Anticoagulation Forum.

08-29
25:56

Blood Global Hematology Editor-in-Chief Shares Vision

In this episode, Editor-in-Chief Shaji Kumar, MD,  a professor of medicine at Mayo Clinic in Rochester, Minnesota, talks with Jorge Cortes, MD, the inaugural editor-in-chief of Blood Global Hematology, one of the latest additions to the growing Blood journals portfolio. Dr. Cortes, director of the Georgia Cancer Center at Augusta University, shares his vision for the journal and his thoughts on how it will impact the hematologic research community around the world. Support for this episode provided by Rigel Pharmaceuticals.

07-17
16:52

One on One With Dr. Fred Appelbaum

In this episode, Contributing Editor Lori Muffly, MD, MS, an associate professor of medicine specializing in blood and marrow transplantation and cellular therapy at Stanford University in California, talks with Fred Appelbaum, MD, executive vice president and deputy director at the Fred Hutchinson Cancer Center in Seattle, and a professor of medicine in the division of hematology and oncology at the University of Washington. They talk about Dr. Appelbaum’s book, Living Medicine: Don Thomas, Marrow Transplantation, and the Cell Therapy Revolution.

06-26
26:25

Genetic Switch System Suggests Targeting of Mutant JAK2 Reverses Myeloproliferative Neoplasms

In this episode, Contributing Editor Bethan Psaila, MD, PhD, an associate professor of hematology at the University of Oxford’s MRC Weatherall Institute of Molecular Medicine, talks with Andrew Dunbar, MD, an assistant professor and independent lab investigator at MD Anderson Cancer Center in Houston, Texas. They discuss Dr. Dunbar’s paper recently published in Cancer Discovery: “JAK2V617F reversible activation shows its essential requirement in myeloproliferative neoplasms.”

06-21
23:49

Venous Thromboembolism Risk Markers and Discontinuing Combined Hormonal Contraceptives

In this episode, Contributing Editor Samuel Wilson, MD, an assistant professor of hematology at the University of North Carolina, Chapel Hill, talks with Marc Blondon, MD, an attending physician in the division of angiology and hemostasis with the University Hospitals of Geneva (Switzerland). They talk about a paper co-authored by Dr. Blondon titled, “Longitudinal profile of estrogen-related thrombotic biomarkers after cessation of combined hormonal contraceptives.” Dr. Wilson wrote about the study in a recent issue of The Hematologist.

05-07
25:41

Growing the Next Generation of Hematologists

In this episode, Editor-in-Chief Shaji Kumar, MD, a professor of medicine at Mayo Clinic in Rochester, Minnesota, talks with Leslie Ellis, MD, a professor of internal medicine at Atrium Health Wake Forest Baptist in Winston Salem, North Carolina. They discuss the ASH Ambassador Program, which is designed to support the recruitment and retention of trainees into hematology. Dr. Ellis is chair of an ASH oversight subcommittee for that program.

04-15
20:14

Women in Hematology

In this episode, Tamara Dunn, MD, a clinical associate professor of medicine in the division of hematology at Stanford University in Stanford, California, and co-chair of ASH’s Women in Hematology Working Group, hosts a conversation with Toyosi Onwuemene, MD, an associate professor of medicine, specializing in hemostasis/thrombosis, at Duke University in Durham, North Carolina, and Nina Shah, MD, the global clinical head for multiple myeloma research and development at AstraZeneca. They talk about career choices and opportunities for women in hematology, both in academic medicine and industry. Support for this episode provided by Sanofi.

03-26
26:39

Four Is Better Than Three: Will We Finally Agree?

In this episode, Contributing Editor Ajai Chari, MD, a professor of clinical medicine and director of the myeloma program at the University of California San Francisco, talks with Pieter Sonneveld, MD, PhD, a professor of hematology at the Erasmus University of Rotterdam in the Netherlands. They discuss Dr. Sonneveld’s recent paper, “Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone for Multiple Myeloma,” published in The New England Journal of Medicine. Dr. Chari wrote about Dr. Sonneveld’s paper in The Hematologist with his Diffusion article, “Four Is Better Than Three: Will We Finally Agree?” Disclosures: Dr. Chari has received consulting fees from Abbvie, Adaptive, Amgen, Antengene, Bristol Myers Squibb, Forus, Genentech/Roche, Glaxo Smith Klein, Janssen, Karyopharm, Millenium/Takeda, and Sanofi/Genzyme and received research funding from Janssen. Dr. Sonneveld has served on the advisory board of Pfizer and has received research funding and served on the advisory boards of Amgen, Bristol Myers Squibb, Celgene, Janssen, and Karyopharm.Music: “Jellyfish in Space” Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 creativecommons.org/licenses/by/3.0/

03-18
23:18

Toward Equity in Access for ALL

In this episode, Contributing Editor Lori Muffly, MD, an associate professor of medicine specializing in blood and marrow transplantation and cellular therapies at Stanford University in California, talks with Roberta Demichelis, MD, an assistant professor in the department of hematology and oncology at the Salvador Zubirán National Institute of Health Sciences and Nutrición in Mexico City. They discuss access to care for patients with acute lymphoblastic leukemia in low- and middle-income countries, especially among Hispanic populations. Music: “Jellyfish in Space” Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 creativecommons.org/licenses/by/3.0/

01-30
26:42

The Brilliant Success of Blinatumomab for Babies With Acute Lymphoblastic Leukemia

In this episode, Contributing Editor Sarah Tasian, MD, associate professor at the University of Pennsylvania School of Medicine and chief of the hematologic malignancies program at the Children’s Hospital of Philadelphia, talks with Rob Pieters, MD, the chief medical officer at the Princess Maxima Center for Pediatric Oncology and professor of pediatric oncology at the University of Utrecht, both in Utrecht, Netherlands. Dr. Pieters is one of the authors of a paper published recently in The New England Journal of Medicine: “Blinatumomab Added to Chemotherapy in Infant Lymphoblastic Leukemia.”Music: “Jellyfish in Space” Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 creativecommons.org/licenses/by/3.0/

11-29
16:13

Editors-in-Chief of Two New ASH Journals Share Their Visions

In this episode, Dr. Shaji Kumar, editor-in-chief of The Hematologist, has a conversation with Drs. Jonathan Licht and Keith McCrae, the editors-in-chief, respectively, of ASH's two new journals Blood Neoplasia and Blood Vessels, Thrombosis & Hemostasis.Music: “Jellyfish in Space” Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 creativecommons.org/licenses/by/3.0/

10-20
25:16

ASH’s Minority Recruitment Initiative Mentorship Program Offers a Win for All

In this episode, Dr. Satiro De Oliveira talks about his own experience with the mentorship program within ASH’s Minority Recruitment Initiative and its impact on trainees coming from underrepresented groups. Dr. De Oliveira is an associate professor in the Division of Pediatric Hematology Oncology at UCLA.Music: “Jellyfish in Space” Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 creativecommons.org/licenses/by/3.0/

09-18
14:20

Results From the Blood and Marrow Transplant Trials Network: How Should We Prevent Graft-versus-host Disease in 2023?

In this episode, Contributing Editor Kate Markey, MBBS, PhD, talks with Shernan Holtan, MD, one of the authors of a paper published recently in The New England Journal of Medicine: “Post-transplantation Cyclophosphamide-based Graft-versus-host Disease Prophylaxis.”Music: “Jellyfish in Space” Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 creativecommons.org/licenses/by/3.0/

09-01
28:05

Genetic Background Influences the Growth of CHIP Clones Within the Bone Marrow, With Drs. Robert Hasserjian and Siddhartha Jaiswal

In this episode, Contributing Editor Dr. Robert Hasserjian has a conversation with Dr. Siddhartha Jaiswal about a recent paper Dr. Jaiswal co-authored: “Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis.”  Dr. Hasserjian is a professor of pathology at Harvard Medical School. He is also the director of the Hematopathology Fellowship Program at Massachusetts General Hospital. Dr. Jaiswal is an assistant professor of pathology at Stanford University School of Medicine. Dr. Hasserjian wrote about Dr. Jaiswal’s paper in his recent Diffusion article in The Hematologist. You can access his Diffusion article online at: https://ashpublications.org/thehematologist/article/doi/10.1182/hem.V20.4.202344/496652/Genetic-Background-Influences-the-Growth-of-CHIP Music: “Jellyfish in Space” Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 creativecommons.org/licenses/by/3.0/

07-07
27:12

Drawing New Blood Into Hematology

In this episode, Drs. Robert Stern and Ronak Mistry talk about their own professional journeys as hematologists, why they love what they do, the medical education for hematologists, and recruitment efforts to bring more students into the field.Dr. Stern is the associate program director with the Dana-Farber Massachusetts General Brigham Fellowship in Hematology and Oncology in Boston. Dr. Mistry is a clinical fellow in the division of hematology and oncology at Vanderbilt University Medical Center in Nashville.Music: “Jellyfish in Space” Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 creativecommons.org/licenses/by/3.0/

06-16
31:39

Anticoagulation and Abnormal Uterine Bleeding: Acknowledging Calls to Action

In this episode, Contributing Editor Dr. Michael Scott is joined by Dr. Sumedha Arya for a conversation with Dr. Cindy de Jong. They discuss a study covered by Drs. Scott and Arya in their recent Diffusion article titled “Anticoagulation and Abnormal Uterine Bleeding: Acknowledging Calls to Action.” Dr. de Jong performed analysis for the study and served as one of the lead authors of the paper published in Blood. To access the Diffusion article online, please click here. Music: “Jellyfish in Space” Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 creativecommons.org/licenses/by/3.0/

05-18
25:13

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