The Lab Report

The world of medicine can be challenging. Clinicians and patients are always looking for more options, more effective treatments… and in the end, more answers. What if there was a way to practice medicine that digs deeper and offers a new perspective? Functional medicine focuses on addressing root causes of disease. At Genova Diagnostics we’ve watched this field evolve and grow for over 35 years…. We’ve not only adapted, we’ve led. Join us as we talk about functional medicine, laboratory testing, and optimizing health. Welcome to the Lab Report.

Licorice Root - The Great Synergizer

Licorice root is a time-honored herbal remedy with a sweet side. Beyond its role in teas and tonics, licorice root has been used for centuries to support digestion, ease respiratory illnesses, and calm everyday inflammation. It is well- known for its synergistic effects with other herbal therapies. Join us as we talk about how licorice root can fit into your wellness routine, the traditions behind its medicinal use, and simple ways you can explore these benefits safely. Today on The Lab Report: 4:00 Licorice root – the plant, not the candy 7:15 Powerhouse synergizer herb 9:45 Bioactive constituents – pharmacologic overview 13:45 Clinical uses – starting with the respiratory tract 16:40 Google it – Dental caries 19:15 In vitro cancer studies  21:30 Estrogenic activities 23:22 Cortisol, fluid retention, electrolytes, blood pressure 25:45 “What’s in a Name?” Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

09-09
32:24

Mitochondrial Dysfunction - The Cell as a City

Mitochondrial dysfunction may be one of the most important topics in the area of personalized and preventative medicine to date. Thousands of articles have been published on the nature of how mitochondria become damaged and what that means for health, longevity, and aging. On today’s podcast, we take a deep dive into the triggers for mitochondrial dysfunction and what clinical conditions are related to damaged mitochondria. We also discuss how to arm your arsenal with everyday items to help stability, protect, and maintain our mitochondria. We also discuss how other systems within and outside the cell are impacted by these “power plants” within.   Today on The Lab Report: 3:45 Break it down: the parts of the cell 8:40 The mitochondria are power plants 9:00 What’s normal? 10:00 Factors that trigger mitochondrial dysfunction 13:20 The mitochondria as our cell’s cohabitant 16:10 Progression of mitochondrial dysfunction 20:10 Clinical conditions associated with mitochondrial dysfunction 21:00 What can we do about it? Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

08-14
23:30

The #1 Complete Protein

Eggs are one of the most widely-consumed, and underappreciated, foods in the human diet. Long regarded as a nutritional powerhouse, eggs are rich in high-quality protein and essential nutrients that are key for health. In fact, eggs are considered the best complete protein – meaning they contain all 9 essential amino acids. But for decades, eggs were caught in the crossfire of the cholesterol debate. In today’s episode, we’ll explore what current research says about the relationship between eggs and heart health, and whether concerns about dietary cholesterol still hold up. We’ll also discuss the role of eggs in weight management, muscle maintenance, eye health, and brain function. Whether you’re someone who eats eggs daily or has questions about whether you should, this episode offers a thoughtful, evidence-based discussion on why eggs have earned their place at the table. Today on The Lab Report: 4:00 Why can't we agree about eggs? 6:00 Eggs are low calorie and a complete protein 8:30 Which is better the whites or the yolks? 10:00 Eggs, choline, and brain health 11:45 Eggs and eyes 17:00 The egg and cholesterol controversy 19:45 We find a way to bring "methylation" into the discussion 23:00 Eggs, satiety, and weight management 24:50 Little known constituents inside eggs 26:30 Other types of eggs and their nutritional value 29:00 Fun facts about eggs: color and bloom 30:20 Which came first, the chicken or the egg?   We also referenced The Methylation Episode which can be listened to here. Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

07-24
34:11

Is Shotgun Sequencing Better Than PCR?

Stool testing technology has advanced rapidly in recent years, with newer methods like PCR and whole-genome sequencing offering faster and more precise insights into the gut microbiome. These innovations have transformed how clinicians approach gut health, allowing for more targeted interventions. However, older technologies—such as microscopy, culture, and enzyme-based assays—still play a valuable role. These methods provide functional insights that molecular tools may miss, such as direct observation of parasites or assessment of digestive markers. The most comprehensive labs recognize that no single method gives the full picture. Instead, combining the strengths of both modern and traditional techniques ensures more accurate, clinically meaningful results. In this episode, we dive into the pros and cons of different laboratory methodologies used in stool testing—from culture and microscopy to PCR and advanced sequencing. We break down how these choices impact accuracy, sensitivity, and clinical usefulness. You'll also learn why Genova Diagnostics stands out for its integrative, evidence-based approach, combining multiple testing methods to deliver the most comprehensive and clinically actionable results available. Today on The Lab Report: 4:00 Technology grows quickly, and the microbiome is complex 7:30 Microbiology culture 12:40 PCR – very precise if done correctly! 17:00 Interpreting the laundry list 20:10 Remember the microscope? 23:30 Whole-genome (shotgun) sequencing pros/cons 27:15 Genova does it all – and well Additional Resources: GI Effects Stool Profile Microbiomix Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

07-16
31:54

NAC...Drug or Super Supplement? [Rebroadcast]

N-acetylcysteine, or NAC, plays an important role in the body when it comes to combating oxidative stress. As a precursor to make glutathione, NAC has been used for decades both as an acute medication and as an over-the-counter supplement. Recently, the line between medication and supplement has been blurred and is now being debated. Today we talk all about N-acetylcysteine - the ways NAC is used and its importance in health and disease. Today on The Lab Report: 2:45 NAC as a drug in acute care settings 4:00 Mechanisms of action in the lung and kidney 7:15 NAC as a daily supplement 10:00 Hmmm…so is it a medication or a supplement? 11:15 Generic drug or herbal constituent? 15:00 Research on NAC in psychiatric disorders 16:16 NAC in polycystic ovary syndrome and fertility 17:40 Safety and side effects 18:50 Question of the Day: What are the other precursors to glutathione and how do we measure them? Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.    See omnystudio.com/listener for privacy information.

07-08
22:46

Turmeric: The Science Behind the Spice

Turmeric is a spice with ancient origins. You’ve seen it in smoothies, teas, curry, and supplements.  Known for its bright yellow color, it has been used for centuries to support whole-body wellness. From inflammation and joint pain to brain and heart health, in this episode we break down what the science says about turmeric and its main constituent curcumin. Join us as we explore turmeric’s long-standing role in health and wellness and zoom in on curcumin. We break down what the science says about curcumin’s therapeutic potential, how it’s absorbed, and whether supplementation is worth the hype. Whether you’re a culinary enthusiast or a health-conscious listener, this discussion of turmeric promises to spice up your knowledge! Today on The Lab Report: 4:30 The history of turmeric 7:30 Inflammation, whole root vs. curcumin 10:45 Oxidative stress, polyphenols, tumors, brain health 12:50 How much turmeric/curcumin per day 15:15 Poor absorption and bioavailability 18:20 Side effects – be aware 19:30 It stains stuff 21:50 Reputable sourcing and MC’s home recipe?   Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

07-01
26:06

The Ultimate Longevity Metric : VO2 Max

There’s a lot of buzz around the topic of longevity. One might argue that every aspect of functional and integrative medicine promotes longevity – which is true. We’re not merely looking to lengthen lifespan we want to promote a HEALTH span. With that in mind, data is compelling. There’s one metric that is often overlooked which happens to be the greatest predictor of longevity: VO2 max. Join us as we dive deep into how VO2 max impacts health, longevity, and overall well-being. We’ll discuss the science, how to measure it, and how to improve this crucial fitness metric. Today on The Lab Report: 4:15 What is VO2 max and how do we use oxygen? 6:00 Mitochondrial biogenesis, VO2 max, and the research 9:00 What’s normal? 10:45 How do you measure VO2 max? 14:10 Improving your VO2 max 17:10 Question of the Day How does Genova assess longevity? Additional Resources: Longevity Landing Page NutrEval Metabolomix+ Methylation Panel Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

06-24
23:07

Alpha-gal Syndrome: Tick-borne Meat Allergy?

As we enter the summer season, many of us will spend countless hours outdoors. We often discuss tick awareness and tick-borne illness, but one tick in particular is getting a lot of press these days. In case you needed another reason to be mindful of ticks, today we discuss Alpha-gal Syndrome. In today’s episode we explore the science behind alpha-gal syndrome – a rare and serious allergy to red meat and other mammal products triggered by a bite from the Lone Star Tick. Tune in to learn how to recognize symptoms and why this syndrome is spreading across many regions and many countries. Today on The Lab Report: 3:30 What is Alpha-gal Syndrome? 6:30 Delayed anaphylaxis? What! 9:50 Epidemiology and prevalence 11:50 Not only red meat – other products 14:55 Diagnosing alpha-gal syndrome 16:20 Tick avoidance and sensitization 18:40 What foods can these patients eat? 20: 15 Question of the Day? Are there herbs that can help? Additional Resources: Alpha-gal Information Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

06-10
23:28

Tinnitus and Hearing: From Cochlea to Cortex

Tinnitus—the phantom ringing, buzzing, or hissing that affects millions. For those patients who suffer with this debilitating condition, it is frustrating to find any relief. For those clinicians trying to treat it, the causes are so multi-faceted, and the treatments seem to be lacking.   Today we break down the physiology of hearing, what can go wrong in the auditory system, and the many potential causes of tinnitus, from noise exposure to neurological conditions. We also examine current treatment options, emerging therapies, and what the latest research says about finding relief. Whether you're a sufferer or just curious, this episode tunes into the facts behind the noise.  Today on The Lab Report:   5:00 Tinnitus – what is it?  7:00 Physiology of hearing sound   10:30 Basic causes of tinnitus  13:45 Pathophysiology & mechanisms  17:45 Loud noise causing tinnitus  22:35 Presbycusis, ototoxicity, hearing loss    25:05 Root causes and treatment of tinnitus   28:00 Functional approach for clinicians  Subscribe, Rate, & Review The Lab Report  Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.  Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net.   And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.   To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.   Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

05-27
32:33

Integrative Cancer Care with Dr. Laura James

Dr. Laura James is a board-certified naturopathic oncologist who has been working with cancer patients for over 20 years. She helps patients who are recently diagnosed with cancer get through the intense steps of conventional treatment – surgery, chemotherapy, and radiation – using natural means like nutrition, herbs, gentle movement, and stress management. In today’s episode, we hear Dr. Laura James discuss her balanced viewpoint on the use of natural therapies in combination with conventional treatment to support cancer patients. Through supplement streamlining, nutritional and botanical recommendations, and lifestyle counseling, her expertise can help you feel better through treatment and beyond. Today on The Lab Report: 4:00 Meet Dr. Laura James and hear how she defines integrative cancer care 9:25 Diet and nutrition – keto, fasting, low carb, protein 14:00 Working alongside conventional oncologists 19:20 Building a care team 24:00 Supporting the chemotherapy journey 27:50 Antioxidants, probiotics, and chemo 32:45 Resilience and the mental emotional rollercoaster 37:40 “Battle language” and vulnerability in cancer 43:50 Preventative care 51:30 Where to find Dr. Laura James? 53:55 The Fireball Additional Resources: LauraJamesND.com Best for Breast Supplements Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

05-13
58:18

ORAC Scores: Debunking Myths and Unraveling Controversy

Are ORAC scores the secret to superfoods—or just marketing fluff? In this episode, we break down what ORAC (Oxygen Radical Absorbance Capacity) really measures and why it stirred up so much controversy. The USDA pulled the plug on publishing the data, but does the concept still hold any value in nutrition science today? In today’s episode, we dive into a myth-busting conversation that explores the science of ORAC, the skepticism, and the truths about antioxidants and health. Today on The Lab Report: 5:15 Review of oxidative stress and antioxidants 8:20 History of the ORAC assay 11:45 Limitations of the ORAC measurement 13:20 USDA vs. Supplement companies 15:30 Foods with high ORAC scores 18:55 Should we still care? What’s the future? Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

05-06
24:27

Fatty Acids & Inflammation [Rebroadcast]

Inflammation is your body’s way of protecting itself from infection, injury, or other insults. Chemical signaling molecules called ‘eicosanoids’ are responsible for creating pain, heat, swelling, and redness. Eicosanoids are made from fatty acids, or dietary fats. We’ve all heard of fish oil and omega-3s being important when it comes to lowering inflammation. But why? In today’s episode, we break down the inflammatory cascade, explain how fatty acids are involved, and we answer the question ‘What in the world is an eicosanoid!?’ Today on The Lab Report: 3:20 What are eicosanoids? 6:05 Fatty acids and the inflammatory cascade 9:10 Lipoxygenase (LOX) and cyclooxygenase (COX) 10:00 The COX eicosanoids – prostanoids and thromboxane  12:10 Leukotrienes, lipoxins, resolvins, and LOX 13:15 Aspirin, fish oil, and heart disease 16:30 Question of the Day How should we measure fatty acids?   Additional Resources: NutrEval Essential & Metabolic Fatty Acids - Bloodspot The omega-3 index as a risk factor for coronary heart disease    Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.  See omnystudio.com/listener for privacy information.

04-24
21:03

Vitamins D & K2 : The Key to Unlocking Strong Bones

If you are worried about keeping your bones strong, there’s more to the story than taking calcium supplements. Vitamin D and vitamin K work together to support strong, healthy bones. Vitamin D helps your body absorb calcium from food, which is essential for building and maintaining bone density. But without enough vitamin K—particularly vitamin K2—that calcium might not end up where it's needed. Vitamin K2 activates proteins that help direct calcium into bones and teeth while keeping it out of soft tissues like arteries. In other words, vitamin D gets the calcium in, and vitamin K makes sure it goes to the right place. In today’s episode, we discuss the important relationship between vitamin D and vitamin K. These 2 fat-soluble vitamins collaborate to support bone density – there’s more to bone health than calcium! Today on The Lab Report: 4:15 Fat-soluble vitamins 6:00 Vitamin D recap 9:35 Bone remodeling 12:05 All about Vitamin K 15:50 Calcium isn’t the whole story 18:25 D3/K2 and cardiovascular health 20:15 Other factors that contribute to bone health 22:40 Question of the Day Do problems with fat digestion cause vitamin deficiency? Additional Resources: Genova Connect Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

04-08
26:52

Zombie Cells

Zombie cells, scientifically known as senescent cells, are damaged or aged cells that refuse to die when they should. Instead, they linger in the body, releasing harmful chemicals that can trigger inflammation and accelerate aging. These cells have been linked to a range of age-related diseases, including arthritis, Alzheimer’s, and even cancer. Dive into the eerie world of 'Zombie Cells' on our latest episode! Uncover how these undead cells wreak havoc in our bodies and what cutting-edge research reveals about their role in aging and disease. Today on The Lab Report: 4:15 Cell turnover, apoptosis, and autophagy vs. zombie cells  7:30 What triggers zombie cells to form and what are telomeres? 10:15 Age-related diseases and inflammation 12:15 Senolytics and strategies to clear zombie cells 17:30 Just practice naturopathic medicine 18:30 Rules to survive a zombie apocalypse Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

04-02
23:54

Why Hair Goes Grey

Such a random topic – gray hair? The technical term for hair graying is canities – again, what a strange word. Who knew? The basic physiology of hair growth and coloration is not something we really think about, but your hair can be a reflection of underlying health or disease. We often talk about the aging process as a marker of oxidative stress -So too with your hair. In this episode, we dive into the science of graying hair. From melanin loss to genetics to some surprising lifestyle connections, we separate fact from fiction and uncover the truth about your hair. Today on The Lab Report: 3:40 Canities, melanin and hair color 7:25 Melanin in hair vs. skin, hair growth stages   12:15 Aging and premature graying, oxidative stress 16:25 Nutrition, hormonal influences, inflammation, stress 18:20 Re-pigmentation???  Or at least delay graying 23:10 Question of the Day How can Genova’s testing help? Additional Resources: Genova Connect NutrEval Metabolomix+ Endo+ Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

03-25
28:48

Hiccups- How They Happen and Hacks to Halt Them

Hiccups- that annoying and at times, painful reflex that sneaks up on you when you least expect it, and sometimes refuses to leave. But what are they really? Is there an evolutionary reason we’ve developed this reflex? When should you be concerned? Can we prevent them? In this episode, we break down the pathophysiology of hiccups (yes, there’s real science behind it) Knowing the science of why they occur, we can separate fact from fiction on how to cure them. From medical insights to strange home remedies, we’re getting to the root of the world’s most inconvenient reflex.  Today on The Lab Report: 3:45 Hiccups – the diaphragm and phrenic nerve 6:30 Pathophysiology of the hiccup and evolution of this reflex 9:30 Diet and lifestyle hiccup triggers 11:00 The rhythmic reflex arc 13:40 When should you be concerned? 15:50 Common cures – fact vs. fiction 21:25 Traditional Chinese Medicine and Charles Osborne 23:09 Take-aways for functional medicine practitioners Additional Resources: Genova Connect Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

03-18
27:13

Optimizing Akkermansia with Christina O'Connor

Akkermansia muciniphila has been getting tons of great press recently. It’s a bacterium in the gut microbiome that thrives by supporting mucin production. However, its potential to enhance metabolic health and support weight management has paved the way for innovative probiotic solutions – which is exactly what a company called Pendulum has done! Pendulum’s products are backed by cutting-edge research showing clinical efficacy. Today we speak with Christina O’Connor, registered dietician and Senior Healthcare Account Manager at Pendulum Therapeutics. Christina breaks down all the latest research on Akkermansia muciniphila and how optimizing levels can lead to greater health outcomes. Today on The Lab Report: 5:30 Christina O’Connor on her love of microbiome science   8:40 Main drivers of gut health 10:15 Why should we care about Akkermansia? 13:05 Can you have too much? 15:20 GLP-1 effects of Akkermansia 17:25 Stool testing on probiotics and supporting colonization 22:40 What’s next for Pendulum? 24:15 The Fireball Additional Resources: Pendulum Discount Codes: Healthcare professionals: Create a provider account HERE for wholesale pricing and get $50 off with code WSGENOVA50. Not a healthcare professional or just want to try it out? Get 20% off your first membership order at pendulumlife.com with code GENOVA at checkout. Genova Connect Discount Code: Are you a consumer interested in checking your levels of Akkermansia? Use the promo code PENDULUM20 for 20% off Genova Diagnostics’ Akkermansia Assessment Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

03-11
28:36

Root Cause Medicine and Testing in Kids

Advanced technologies and personalized approaches have been the hallmark of what we do here at Genova Diagnostics. We are frequently asked how this testing can be applied in pediatrics. Our testing is widely used to help empower parents to get to the root cause of some common childhood concerns. But there are some caveats to consider when interpreting results. Every child is unique – so why shouldn’t their healthcare be? In this episode, we dive into the world of personalized medicine for children and how Genova’s cutting-edge testing can unlock better health outcomes for kids. Today on The Lab Report: 3:25 Approaching common pediatric ailments 6:00 Root causes of skin issues, rashes, eczema 9:15 Food Sensitivity Testing and caveats 11:00 Stool testing in pediatrics – interp is different! 15:15 Pediatric nutrition testing – benefits and things to know 17:40 Childhood obesity and testing for metabolic syndrome 20:00 “What is it?” Game Additional Resources: GI Effects Metabolomix+ Food Sensitivity+ Cardio Check Genova Connect Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

03-05
25:43

Dr. Rick Johnson & Neil Gyte on Appetite, Chronic Disease, and the Damaging Impact of Sugar

We all know sugar isn’t great for our health. But is all sugar created equal? In this eye-opening podcast, we speak with the team from RxSugar. Their company creates and promotes a healthy sugar called allulose. Yes, a healthy sugar! Dr. Rick Johnson is a leading researcher on the hidden dangers of sugar. He discusses the impact of how sugar and fructose can hijack your cravings, fuel inflammation, and contribute to chronic disease. We also meet former Google Exec Neil Gyte. His personal journey toward metabolic health found him crossing paths with the science team at RxSugar. Neil joined their company and now continues his mission to make 1 billion people world-wide metabolically healthy while promoting the benefits of allulose. Listen in and enjoy this fascinating conversation! Today on The Lab Report: 5:10 Meet Dr. Richard Johnson and Neil Gyte 7:00 Fructose, appetite, and leptin resistance 14:25 Sugar industry and sub-optimal clinical trials 22:15 Fructose, carbs and the polyol pathway, uric acid levels 29:40 Neil’s a-ha moments toward metabolic health 34:00 Joining RxSugar -Allulose as a game-changer 41:40 Other artificial sweeteners 46:40 Allulose and the ketogenic diet 49:30 1BMH and diet/lifestyle factors 54:25 1BMH vision and the Loch Lomond swim 59:35 Where you can learn more! 1:02.10 The Fireball   Additional Resources: RxSugar.com  **PROMO CODE 1BMH for 20% Discount!*** (expires in June) YouTube Videos Dr. Nicholas Norwitz: Allulose: Healthiest Sugar in the World & GLP-1  Thomas DeLauer: The Only Sweetener that Literally Shrinks Belly Fat Published Papers: Alluose RCT, glucose and insulin - Journal of Functional Foods Allulose and Weight Loss - Nutrients Allulose and GLP-1 release - Nature The Metabolic and Endocrine Effects of a 12-week Allulose-Rich Diet - Nutrients Brain activity and sugar - Nutr Neuroscience Sweet Taste Receptor Activation  (and related article) Allulose & Intestines Allulose, Fructose, Glucose and the Small Intestine - Nutrients Alluose & Tight Junction Regulation - Journal of Functional Foods ​​Microbiome Allulose and the gut Microbiota  Allulose and High Fat Diets - Microbiome - Nutrients   Fructose & Metabolic Syndrome Fructose & Metabolic Syndrome - Cell Metabolism Fructose, Intracellular Pathway - J Biol Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

02-25
01:08:25

Garlic! - Nature's Secret Weapon

Garlic isn't just a kitchen staple—it’s a natural powerhouse of health benefits! Packed with antioxidants and sulfur compounds like allicin, garlic supports heart health by lowering blood pressure and cholesterol, strengthens the immune system, fights inflammation, and so much more. With its antibacterial and antiviral properties, garlic has been used for centuries as a natural remedy for colds, infections, and overall wellness. Whether eaten raw, cooked, or taken as a supplement, garlic is a simple yet powerful way to boost your health naturally. Join us as we discuss this unsung herbal hero. Today on The Lab Report: 3:00 Garlic is a vegetable and a medicine 7:30 Herbal constituents vs. whole plants 9:00 Allicin 11:50 Cardiovascular health and immunity 14:20 Antimicrobial and antiviral properties 15:20 Garlic is useful in so many clinical conditions 17:20 Which form is best? 19:25 Get Outta Here!!!!!!!! Additional Resources: Subscribe, Rate, & Review The Lab Report Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review. Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: podcast@gdx.net. And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing. To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect. Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.See omnystudio.com/listener for privacy information.

02-15
24:06

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