The Long Run with Luke Timmerman

"The Long Run" Antarctic explorer Ernest Shackleton would appreciate today's biotech. Scientific entrepreneurs of the 21st century must be ready for what Shackleton called the “hazardous journey, bitter cold, long months of complete darkness, constant danger, safe return doubtful, honor and recognition in case of success.” Today, the men and women who strive to apply science for the betterment of human health have a historic opportunity. They need stamina and resilience to achieve something meaningful. Biotech’s relationship with the society that sustains it has never been more tenuous. Join host Luke Timmerman for in-depth, thought-provoking conversations with biotech newsmakers pursuing these great opportunities of the 21st century.

Ep167: Leslie Williams on transfer RNA therapies

Leslie Williams, CEO of Boston-based hC Bioscience, on developing transfer RNA therapies.

11-06
01:11:28

Ep166: Chris Garcia on Engineering Protein Drugs for Cancer, Autoimmunity

Chris Garcia, professor at Stanford University and co-founder of several biotech startups, on using protein engineering to advance new treatments for cancer and autoimmune diseases.

10-15
01:03:35

Ep165: Zach Hornby on Tackling Cancer Drug Resistance

Zach Hornby, CEO of San Diego-based Boundless Bio, on tackling cancer drug resistance.

09-26
01:02:45

Ep164: Ted Love and Alan Anderson on Raising the Bar for Sickle Cell Disease Patients

Ted Love, chairman of BIO, and Dr. Alan Anderson, executive director of Sickle Forward, on how to improve quality of life for sickle cell disease patients around the world.

09-05
56:39

Ep163: Sarah Boyce on RNA Medicines for Muscle Diseases

Sarah Boyce, CEO of San Diego-based Avidity Biosciences, on RNA medicines for rare muscle diseases.

08-14
01:08:16

Ep162: Sean McClain on AI for Biologic Drug Discovery

Sean McClain, CEO of Absci, on using AI to speed up biologic drug discovery.

07-16
01:05:59

Ep161: Jeff Stein on a Long-Lasting Flu Drug

Jeff Stein, CEO of San Diego-based Cidara Therapeutics, on a long-lasting drug against flu.

07-01
01:08:51

Ep160: Abe Ceesay on Precision Neuroscience

Abe Ceesay, CEO of Boston-based Rapport Therapeutics, on a precision medicine approach to neuroscience drug discovery.

06-17
01:08:48

Ep159: Jimi Olaghere on Being Functionally Cured of Sickle Cell Disease

Jimi Olaghere is one of the first patients to have been functionally cured of sickle cell disease with a CRISPR gene-edited cell therapy.

06-03
01:07:22

Ep158: David Younger and Randolph Lopez on SynBio & AI for Discovery

David Younger and Randolph Lopez, co-founders of A-Alpha Bio, on using synthetic biology and AI to discover new biologic drugs.

05-20
01:00:44

Ep157: Vineeta Agarwala of A16Z on Investing in AI for Drug Discovery

Vineeta Agarwala, general partner at A16Z's Bio & Health fund, on investing in AI for drug discovery.

05-01
56:33

Ep156: David Liu on New Tools and Techniques for Biology

David Liu, professor of chemistry at Harvard University and co-founder of multiple biotech companies, including Beam Therapeutics and Prime Medicine.

04-16
01:52:57

Ep155: Valerie Daggett on Early Detection, and Treatment, of Alzheimer's

Valerie Daggett, founder and CEO of Seattle-based AltPep, on early detection and treatment of Alzheimer's.

03-06
01:02:37

Ep154: Robert Ang on CRISPR to Protect Bone Marrow & Attack Cancer

Robert Ang, CEO of Cambridge, Mass.-based Vor Bio, on using CRISPR gene editing to alter bone marrow transplants and improve treatment of acute myeloid leukemia.

02-09
01:03:14

Ep153: Rick Young on Studying Gene Expression for Drug Discovery

Rick Young, professor at MIT and co-founder of Syros Pharmaceuticals, CAMP4 Therapeutics, Omega Therapeutics, and Dewpoint Therapeutics, on studying gene expression for drug discovery.

01-22
01:01:43

Ep152: Jens Eckstein on Investing in Healthy Aging

Jens Eckstein, investment partner at Hevolution Foundation, on investing in healthy aging.

01-10
01:05:05

Ep151: Shelley Force Aldred and Nathan Trinklein on Bispecific Antibodies for Cancer

Shelley Force Aldred and Nathan Trinklein, co-founders of Rondo Therapeutics, on the opportunity with bispecific antibodies for cancer.

12-26
01:03:55

Ep150: Jeff Jonker on the Small Molecule Drug Discovery Renaissance

Jeff Jonker, CEO of San Diego-based Belharra Therapeutics, on the renaissance in small molecule drug discovery.

12-13
01:03:48

Ep149: Nancy Stagliano on Precision Neuroscience

Nancy Stagliano, CEO of South San Francisco-based Neuron23, on bringing precision medicine to neuroscience drug discovery.

11-29
01:01:53

Ep148: Diana Brainard on the Fight Against Infectious Disease

Diana Brainard, CEO of AlloVir, on leading the fight against infectious diseases.

11-13
01:03:27

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