The Neuro Experience

I used to think of fiber as just “good for digestion,” but it turns out this single nutrient can lower cholesterol as powerfully as a statin—and do so much more for your brain, gut, and longevity. In this minisode of The Neuro Experience, I sit down with Dr. Rupy Aujla — NHS doctor, author, and founder of The Doctor’s Kitchen — to break down the science behind fiber and why it’s one of the most underrated tools for preventing heart disease and inflammation. This episode features highlights from our full conversation, which premiered August 5th, 2025. Watch the full episode here → https://www.youtube.com/watch?v=Jay-Sg2sg6s Connect with Dr. Rupy Aujla: Website: The Doctor’s Kitchen Instagram: @doctors_kitchen Books: The Doctor’s Kitchen & Eat to Beat Illness *** Topics discussed: 00:18 – The TikTok “fiber maxxing” trend explained 00:42 – How to transition from low-fiber to high-fiber safely 01:02 – How fiber binds cholesterol and removes it from the body 01:26 – Feeding your gut microbes: the real reason fiber matters 02:10 – What short-chain fatty acids do for inflammation and longevity 03:00 – How fiber increases LDL receptor activity in the liver 03:42 – How 60 days of high-fiber eating lowers ApoB and LDL 04:03 – The “Portfolio Diet” that rivals statins 05:08 – The best fiber-rich foods: oats, barley, soy, nuts, seeds 06:14 – What to know about oats, glyphosate, and processing 07:16 – The perfect high-fiber breakfast recipe 07:53 – How food can match statin effects (and go beyond) 09:10 – The one daily change to reduce heart attack and stroke risk 09:26 – Dr. Rupy’s B.B.G.S. formula for everyday health 10:13 – How fiber diversity transforms cholesterol and gut health *** I’m Louisa Nicola — clinical neurophysiologist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

In your 30s, everything changes, and your fitness plan should too. In this episode of The Neuro Experience, I sit down with Sam Christine, mom of two, marathoner, macro coach, and creator of the EMPWR app, to unpack what actually works for women when fat loss stalls, hormones crash, and burnout creeps in. After pushing her body too far during marathon training, Sam lost her period for 13 months. The cause? Undereating, overstressing, and overtraining, all while juggling career, motherhood, and a crumbling marriage. Now, she’s helping thousands of women rebuild their health from the inside out. About Sam: Samantha Christine is a nutritionist, certified trainer, and founder of EMPWR by Sam—a fitness app helping women train smarter, fuel better, and build lasting strength. As a mom of two, she makes fitness realistic and sustainable through workouts, recipes, and mindset shifts that empower women to feel strong and confident. Where to find Sam: Instagram: @samcfit The EMPWR Podcast EMPWR by Sam Fitness App  *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Function Health: Visit https://functionhealth.com/louisa or use gift code NEURO100 at sign-up to own your health. Thrive Market: Go to https://ThriveMarket.com/neuro to get 30% off your first order, and a free $60 giftBrickhouse Nutrition: Get 20% off when you use promo code NEURO at https://brickhousenutrition.com/  NOCD: Book a free 15 minute call to get started: https://learn.nocd.com/NEURO. Dream Recovery Use code ‘NEURO15’ for 15% off your order at checkout at https://dreamrecovery.io/  Calm Get 40% off a Calm Premium Subscription at https://calm.com/louisa  *** I’m Louisa Nicola — clinical neurophysiologist  — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed:  00:00 – Intro 02:17 – How Sam turned her life around 04:00 – The Critical Decade for Women’s Health 06:20 – Under-Fueling, Hormones & Recovery 13:50 – From Rock Bottom to EMPWR 17:30 – Reinvention: Friendship, Clean Living & Divorce 23:20 – How to Build Muscle & Lose Fat (The Right Way) 28:30 – Nutrition Myths & Mindset Shifts 35:30 – Women’s Health, Fertility & Family 38:00 – Navigating Hormonal Shifts & Reinvention 43:00 – Exercise as Brain Medicine 51:30 – Biohacking, Bloodwork & Longevity Tools Learn more about your ad choices. Visit megaphone.fm/adchoices

Every 80 seconds, a woman dies from heart disease — yet most still think cancer is the bigger threat. In this minisode, I sit down with Dr. Jeremy London, board-certified cardiothoracic surgeon, to unpack why women’s cardiovascular risk skyrockets after menopause and how hormones, inflammation, and lifestyle choices all connect. This episode features highlights from our full conversation, which premiered July 24th, 2025. Watch the full episode here → https://www.youtube.com/watch?v=7jbvQRZgb3w Dr. London explains how declining estrogen drives visceral fat, raises cholesterol, and fuels chronic inflammation — creating a “perfect storm” for heart attacks, strokes, and even Alzheimer’s. From estrogen and inflammation to cholesterol, exercise, and sleep — this conversation exposes the real science behind heart and brain health. If you’ve ever wondered how to protect yourself from the #1 killer of women, this episode will change how you think about prevention, hormones, and longevity. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** I’m Louisa Nicola — clinical neurophysiologist  — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Why Women’s Heart Risk Triples After Menopause 00:55 – Estrogen’s Role: Anti-Inflammatory and Protective 01:45 – Weight Gain, Visceral Fat, and Inflammation 02:09 – Cholesterol, LDL, and Rising Risks Post-Menopause 02:38 – The “Perfect Storm” of Metabolic Decline 03:13 – How the Women’s Health Initiative Misled Women on Hormones 03:36 – Estrogen, Brain Health, and Alzheimer’s Connection 04:45 – The #1 Global Killer: Cardiovascular Disease 05:26 – What “Heart Disease” Really Means 06:00 – Cholesterol Explained: HDL, LDL, and Triglycerides 07:37 – Why ApoB Is a More Accurate Marker 09:18 – Plaque Formation and Early Intervention 10:11 – The Study That Reversed Heart Aging by 20 Years 11:24 – VO₂ Max, Zone-5 Training, and Longevity 12:16 – Resistance Training and “Muscle as the Organ of Longevity” 13:09 – Why Consistency Beats Intensity 13:57 – The Sitting Disease and Daily Movement 14:22 – The Power of Nutrition: “Your Body Is the Soil” 15:02 – Whole Foods, Processed Diets, and Alcohol 16:24 – Can Plaque Be Reversed? The Truth 17:11 – Alzheimer’s and Lifestyle: Prevention Starts in Your 30s 18:19 – The Final Pillar: Sleep and Recovery 19:28 – Why Sleep Fuels Brain and Heart Health 20:12 – Which Health Pillar Matters Most for You Learn more about your ad choices. Visit megaphone.fm/adchoices

In this powerful episode, board-certified urologist Dr. Kelly Casperson exposes the gender bias in medicine and reveals why testosterone may be the missing link in women’s mood, motivation, and longevity. One of the few female urologists in the U.S., Dr. Kelly is rewriting the narrative on hormones—explaining why testosterone isn’t “just for men” and why, after 90 years, the FDA still hasn’t approved it for women. Her message is clear: women are not broken. Whether you’re in your 30s, perimenopause, or beyond, this episode will change how you see your biology—and your power. About Dr. Casperson Dr. Kelly Casperson is a urologist, author, speaker, and educator transforming the way women understand their bodies. She empowers women of all ages to embrace sexual health, hormone balance, and intimacy with confidence and curiosity. With humor and candor, she dismantles shame-based myths and teaches one powerful truth: You Are Not Broken. Follow Dr. Kelly Casperson: Instagram: @kellycaspersonmd Podcast: You Are Not Broken Website: https://kellycaspersonmd.com/ *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Troscriptions: Go to https://www.troscriptions.com/neuro | Code: NEURO for 10% your first order Ketone IQ: Go to https://www.ketone.com/NEURO for 30% OFF your subscription order Timeline: Head to https://timeline.com/neuro to get 20% off Manukora: Head to https://www.manukora.com/neuro to save up to 31% plus $25 worth of free gifts with the Starter Kit. Brickhouse Nutrition: Check out the university study and get 20% off when you use promo code NEURO at https://brickhousenutrition.com. Jones Road Beauty:  Head to https://Jonesroadbeauty.com and use code NEURO at checkout. *** I’m Louisa Nicola — clinical neurophysiologist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Intro 03:14 – From Sex Ed to Menopause 05:15 – FDA Bias & Hormone Approval 07:26 – Redefining HRT as PET (Progesterone, Estrogen, Testosterone) 07:51 – Hormones 101 & Testosterone Misconceptions 10:13 – Perimenopause vs. Stress 11:51 – The “Bricks of the House” Analogy 13:57 – Symptoms of Low Testosterone in Women 15:15 – Lab Values vs. Reality 17:14 – DHEA & Supplementation 20:10 – Emotions on Testosterone 21:23 – Testosterone & Mental Health 22:33 – Vitamin D & Hormone Synergy 23:07 – Debunking Testosterone Myths 26:35 – The “Married-Only” Paradox 27:14 – Perimenopause Misdiagnosis 28:19 – Myth #2 – Masculinization Fear 29:15 – Fertility & Testosterone 30:07 – Pregnancy & Safety 31:01 – Blood Tests Explained 32:41 – Dr. Casperson’s Book & Treatment Guidance 33:24 – Contraindications & Safety 34:06 – Breast-Cancer Data 35:12 – The Menopause Divorce Rate 36:47 – Untreated Menopause & Relationships 39:25 – Testifying at the FDA 41:35 – The Estrogen Box Warning 43:35 – Why the FDA Still Hasn’t Acted 45:59 – Risk Tolerance Gap 46:17 – Systemic Discrimination in Medicine 47:28 – Neurological Protection of Testosterone 48:11 – Alzheimer’s & Hormone Decline 50:11 – Prevention vs. Treatment 52:04 – Brain Receptors & Protection 55:14 – The Brain Literally Eats Itself 57:18 – FDA Hearing Reflection  Learn more about your ad choices. Visit megaphone.fm/adchoices

Can medications like Ozempic and Mounjaro actually do more than help you lose weight? This minisode features highlights from our full conversation, which premiered October 7th, 2025. Watch the full episode here → https://youtu.be/AcVIiy201H4?si=nlaFL3JnoZHxQVFh Dr. Rocio Salas-Whalen and I explore the difference between GLP-1, GIP, and triple-agonist drugs — and what’s next in obesity medicine, how estrogen changes after 40 drive midsection weight gain and inflammation, why GLP-1s reduce cancer and Alzheimer’s risk through anti-inflammatory and neuroprotective effects and how obesity and insulin resistance impact fertility and PCOS — and how GLP-1s can help.If you’ve ever wondered whether GLP-1s are just “weight loss shots” or a real step forward in metabolic and brain health — this “minisode” is a must-listen. *** Follow Dr. Salas-Whalen: Instagram: @drsalaswhalen TikTok: @drsalaswhalen @strengthmd @thedryrevolution *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Intro 00:04  – The Probiotic GLP-1 Myth 00:19 – The “iPhone Evolution” of GLP-1 Drugs 00:52 – GLP-1 vs GIP vs Triple Agonists Explained 01:24 – Phase 3 Results & Massive Weight Loss Outcomes 01:38 – The Role of Glucagon in Weight Loss 01:56 – Menopause, Estrogen & Midlife Weight Gain0 3:06 – The “Fat Shift” After 40 04:01 – Can You Combine HRT and GLP-1s? 06:17 – “Willpower” vs Biology in Obesity 07:49 – The Genetic and Hereditary Roots of Obesity 08:57 – Breaking the Transgenerational Cycle 09:30 – Thyroid Cancer Myths and GLP-1 Safety 10:49 – GLP-1s and Breast Cancer Prevention 12:06 – Inflammation as the Root of Disease 12:28 – Neuroprotection and Alzheimer’s Prevention 13:17 – GLP-1s, PCOS & Fertility Benefits 13:53 – The Positive Ripple Effect on Mental Health 14:21 – GLP-1s Reduce Alzheimer’s Risk by 33% 14:58 – The Future of Metabolic Health Learn more about your ad choices. Visit megaphone.fm/adchoices

Can strength training, sprinting, and nutrition truly transform women’s hormones, metabolism, and longevity? In this episode, Dr. Stephanie Estima — chiropractor, women’s health expert, and founder of The Estima Method — breaks down the science of female physiology, muscle, and midlife health. We cover why walking isn’t enough, how hormones shape muscle and bone, and why protein and strength training are essential “medicine” for women over 35. Expect myth-busting, practical tools, and empowering insights to help you train and live in sync with your biology. About Dr. Stephanie Estima: Dr. Estima began her career in chiropractic care, where she developed a deep interest in neuroscience, biomechanics, and the body’s connection between movement and the brain. After noticing how differently men and women respond to the same health strategies, she became passionate about helping women navigate hormones, metabolism, and midlife health. Where to find Dr. Estima: Instagram: @dr.stephanie.estima Website: https://drstephanieestima.com *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Function Health: Visit https://functionhealth.com/louisa or use gift code NEURO100 at sign-up to own your health. Ketone IQ: Go to https://www.ketone.com/NEURO for 30% OFF your subscription order PUORI: Go to https://puori.com/NEURO and use the code NEURO at checkout for 20% off. AquaTru: Go to https://AquaTru.com now for 20% off (your purifier) using promo code NEURO. AquaTru even comes with a 30-day best-tasting water guarantee. Caraway: Visit https://Carawayhome.com/neuro and take an additional 10% off your next purchase. Jones Road Beauty:  Head to https://Jonesroadbeauty.com and use code NEURO at checkout. *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Intro 03:14 – Reassessing Hormone Therapy in 2025 04:24 – The Rise of HRT & Social Media Awareness 05:37 – Balancing the Conversation: HRT Pros & Cons 06:42 – Lifestyle Levers That Matter More 08:05 – Why Walking Isn’t Enough Exercise 10:59 – Muscle Quality & Metabolism Explained 12:29 – Type 1 vs. Type 2 Muscle Fibers 16:25 – Glucose, Muscle, and Longevity18:07 – Bone Health & Estrogen 20:33 – The Power of Impact Training 22:28 – How to Build a “Prescription for Health” 24:06 – The Zone 2 Misconception 26:29 – Progressive Overload & The “Weighted Vest” Myth 27:45 – Sample Lower-Body Workout Blueprint 34:03 – Learning Proper Squat Mechanics 35:28 – The Power of Deadlifts & Hip Hinge Movements 36:46 – Glute Bridges & Unilateral Training 38:35 – Nutrition & Midlife Metabolism 39:47 – How Hormones Change Body Composition 42:06 – Sleep, Insulin, and the Estrogen Cascade 43:59 – Strength Training as Hormone Therapy 45:06 – LDL & Visceral Fat Connection 46:04 – Fasting & Female Metabolism 47:17 – Why Aggressive Fasting Backfires for Women 50:53 – The Dark Side of Fasting Culture 53:22 – Practical Guidelines for Eating Windows 54:03 – Under-Fueling & Protein Deficiency in Women 55:09 – Appetite, GLP-1 Drugs & Metabolic Health Learn more about your ad choices. Visit megaphone.fm/adchoices

Can obesity, menopause, and even Alzheimer’s risk be transformed with one class of medications? Triple board-certified endocrinologist Dr. Rocio Salas-Whalen joins The Neuro Experience to unpack the science behind GLP-1 therapies, sustainable weight loss, and hormone health. One of the earliest physicians to adopt GLP-1 treatments, Dr. Salas-Whalen has redefined how obesity and midlife health are managed—showing why weight gain isn’t about “willpower” but biology, inflammation, and longevity. A leader in obesity and hormone medicine, Dr. Salas-Whalen founded StrengthMD and The Dry Revolution, sharing evidence-based wellness insights worldwide. Her upcoming book, Weightless: A Doctor’s Guide to GLP-1 Medications, Sustainable Weight Loss, and the Health You Deserve, launches Dec 30, 2025 (U.S./Canada) and early 2026 worldwide. Follow Dr. Salas-Whalen: Instagram: @drsalaswhalen TikTok: @drsalaswhalen @strengthmd @thedryrevolution Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Puori Go to https://puori.com/NEURO and use the code NEURO at checkout for 20% off. Wildgrain For a limited time, Wildgrain is offering our listeners $30 off the first box - PLUS free Croissants in every box - when you go to https://Wildgrain.com/NEURO to start your subscription.  OSEA Get 10% off your first order sitewide with code NEURO at https://OSEAMalibu.com. You’ll get free samples with every order, and free shipping on orders over $50. Honeylove Save 20% Off Honeylove at https://honeylove.com/NEURO. Brickhouse Nutrition Check out the university study and get 20% off when you use promo code NEURO at https://brickhousenutrition.com. Eko Health Get $50 off, plus a FREE custom chest piece cover ($25 value) when you go to https://ekohealth.com/NEURO  *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Intro 01:44 – Dr. Rocio’s Journey into Endocrinology 02:38 – Discovering the First GLP-1 Drug 03:29 – Early Results & FDA Approval 05:00 – GLP-1 101: What It Is + How It Works 06:28 – Natural vs Synthetic GLP-1s 07:09 – GLP-1s & Alzheimer’s Link 08:20 – GLP-1s vs Bariatric Surgery 09:32 – Rewiring Cravings in the Brain 11:24 – Anti-Inflammatory Benefits of GLP-1s 11:24 – Ad 15:19 – Ozempic, Mounjaro & Next-Gen GLP-1s 17:02 – GLP-1s & Women’s Hormones 19:26 – Will You Be on GLP-1 Forever? 21:35 – The Myth of Willpower 23:22 – Breaking Generational Obesity Cycles 24:43 – GLP-1 & Thyroid Cancer Myth 25:55 – Ad27:55 – GLP-1s Reduce Cancer Risk 29:12 – Inflammation & GLP-1s 30:00 – GLP-1s & Fertility (PCOS) 31:27 – GLP-1 Meds Cut Dementia Risk by 33% 32:04 – Muscle Loss on GLP-1s? 33:14 – Muscle: Your Body’s Anti-Inflammatory Organ 34:01 – How to Eat Enough Protein on GLP-1s 35:19 – Tracking Your Body Composition 36:57 – Build Muscle While Losing Weight 37:25 – GLP-1 Side Effects & How to Avoid Them 38:24 – The GPS Method (GLP-1 + Protein + Strength) 38:24 – Ad 41:15 – Exposing “GLP-1 Gummies” & Celeb Hype 41:34 – Microdosing & Maintenance Explained 45:01 – The Emotional Shift in Patients 46:07 – The Future of GLP-1s 48:04 – Ending Chronic Disease Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of The Neuro Experience, I sit down with Dr. Kellyann Niotis—one of the first fellowship-trained preventive neurologists—to reveal how you can protect your brain long before symptoms of Alzheimer’s or dementia appear. With Alzheimer’s cases expected to triple by 2050, Dr. Niotis explains the difference between dementia types, the real role of genes like ApoE4, and why lifestyle choices may be more powerful than genetics. If you want actionable tools to lower your risk, strengthen your memory, and understand the future of preventive neurology, this conversation delivers science-backed strategies you can start applying today. About Dr. Kellyann Niotis: Dr. Kellyann Niotis is the first fellowship-trained preventive neurologist focused on reducing risk for Alzheimer’s, Parkinson’s, and Lewy Body Dementia. She launched the nation’s first Alzheimer’s Prevention Clinic at Weill Cornell and now leads early-detection and brain health research at the Institute for Neurodegenerative Diseases Florida. Her work appears in leading medical journals and has been featured by CNN. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode: Timeline: Head to⁠ http://timeline.com/neuro⁠ to get started. Beam: Visit ⁠http://shopbeam.com/TNE⁠ and use code TNE at checkout. Jones Road Beauty: Head to ⁠http://Jonesroadbeauty.com⁠ and use code NEURO at checkout. After you purchase, they will ask you where you heard about them. PLEASE support our show and tell them our show sent you. NOCD: Head to ⁠http://learn.nocd.com/NEURO⁠ and book a free 15 minute call to get started. Eko Health: Go to ⁠http:/ekohealth.com/NEURO ⁠ for up to $50 off, plus a free chest piece cover.  *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ *** Topics discussed: 00:00 – Introduction 01:25 – Preventative neurology 02:23 – Dementia vs. Alzheimer’s & Other Types of Dementia 04:08 – What Is Alzheimer’s? 05:26 – Clinical Diagnosis: Imaging & Symptoms 07:07 – How Amyloid Disrupts Neural Communication 09:48 – Genetics vs. Lifestyle: Public Misunderstanding 12:02 – Role of Family History & Genetic Risk 14:04 – The ApoE4 Gene Explained15:07 – ApoE Variants 17:08 – ApoE4 and Lipid Transport in the Brain 18:35 – Immune Response & Infection Susceptibility 20:05 – Hormones: Key Role in Brain Health 21:08 – Genotypes & Risk Multipliers 23:01 – ApoE4 Not Always Deterministic: Population Studies 24:15 – Other Genetic Factors Beyond ApoE 25:13 – Biomarkers: Current Use & Limitations 27:13 – Risks of Self-Testing Biomarkers 28:45 – Why Two-Thirds of Patients Are Women 29:46 – Estrogen, Menopause & Neuroprotection 32:07 – Testosterone & Dementia Risk 35:01 – LDL, ApoB & Brain Health Debate 37:01 – Statins & Dementia: Myths vs. Evidence 39:08 – Fear & Misconceptions Around Cholesterol 41:09 – Lipoprotein(a) & Vascular Dementia Risk 44:39 – Brain Vasculature & Hypertension 49:15 – New Alzheimer’s Drugs & Risks 55:32 – Why Rates Keep Rising (Lifestyle & Stress) 58:11 – Early Signs 01:00:23 – Tau Protein, Tangles & Neuronal Damage 01:05:49 – Keto vs. Mediterranean 01:07:14 – Personalization & Preference for Mediterranean Diet Learn more about your ad choices. Visit megaphone.fm/adchoices

Parkinson’s disease is the fastest-growing neurological condition in the world—and according to Dr. Ray Dorsey, it doesn’t have to be this way. In this episode, I sit down with Dr. Dorsey, a leading neurologist, Parkinson’s researcher, and tireless advocate for rethinking chronic illness. Together, we unpack why the rates of Parkinson’s have doubled in the last 25 years and explore a bold claim: Parkinson’s is largely a manmade and preventable disease.Dr. Dorsey’s message is urgent yet hopeful: prevention is possible, but it requires awareness, advocacy, and collective action. Dr. Ray Dorsey is a neurologist and one of the world’s foremost voices in Parkinson’s disease research and care. With deep clinical expertise and a passion for health care innovation, he is reshaping how we understand and address chronic illness. His parents were both psychiatrists, and he knew from first grade that he wanted to become a doctor. Today, he combines that lifelong love of learning with a mission to prevent Parkinson’s and improve the lives of millions worldwide. ***  Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey.  ***  A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Troscriptions: Go to www.troscription.com/neuro | Code: NEURO for 10% your first order Ketone IQ:  Go to https://ketone.com/NEURO for 30% OFF your subscription order + receive a free gift with your second shipment. Caraway: Visit https://carawayhome.com/neuro and you can take an additional 10% off your next purchase. Manukora: Head to https://manukora.com/NEURO to save up to 31% plus $25 worth of free gifts with the Starter Kit. Rula: Go to https://rula.com/NEURO to get started today.  Puori: Go to https://puori.com/NEURO and use the code NEURO at checkout for 20% off. *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ *** Learn more about Dr. Ray Dorsey’s work: Ending Parkinson’s DiseaseExplore Parkinson’s 25 recommendations in his book The Parkinson’s Plan to reduce your risk. Topics discussed: 00:00:00:00 —  Intro  00:01:45:16 — Rising rates of Parkinson’s & preventability00:03:59:20 — How it starts & prodrome (decades-long progression).00:05:27:22 — TCE & contaminated water/sites (Camp Lejeune, Woburn, Brooklyn, Silicon Valley). 00:10:36:02 — Dry cleaning exposure (perc), apartments above cleaners. 00:12:31:08 — Pathophysiology I: mitochondria, substantia nigra, alpha-synuclein. 00:17:06:16 — Pathophysiology II: body-first vs brain-first; REM sleep behavior disorder.00:23:52:16 — Diagnosis: clinical features, imaging/biomarkers. 00:25:44:09 — Genetics (12.5%) & environmental susceptibility; TCE history/regulation. 00:29:12:23 — Pesticides: chlorpyrifos, paraquat; golf-course & agricultural exposure. 00:34:14:00 — Consumer guidance: wash produce; prioritize organic meat/dairy; contamination case studies. 00:37:58:11 — Sex differences & exposure sociology; possible estrogen protection. 00:39:37:03 — Management mindset: no cure; reduce exposures; 25 recommendations; occupational risks.00:41:05:15 — Air pollution & purifiers: PM2.5, blood–brain barrier bypass, home monitoring.00:46:53:17 — Water purification: filters vs RO; well-water testing & regulation gaps. Learn more about your ad choices. Visit megaphone.fm/adchoices

Menopause is finally in the spotlight — but most women still don’t understand what’s happening to their bodies in their late 30s, 40s, and beyond. Even worse, many doctors misdiagnose or dismiss symptoms like brain fog, night sweats, weight gain, and mood swings as “just stress.” About Dr. Alicia Robbins: Dr. Alicia Robbins is a board-certified Gynecologist and Lifestyle Medicine physician, founder of The Elm, and creator of The Robbins Method. She is recognized as a leading voice in perimenopause and midlife health, dedicated to providing compassionate, proactive care and rewriting the narrative on women’s midlife. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Function Health Visit https://www.functionhealth.com/louisanicola and use code NEURO100 or use gift code NEURO100 at sign-up to own your health. The first 1000 get a $100 credit toward their membership.  FIGSYou can get 15% off your first order at https://www.wearfigs.com with the code FIGSRX.  Honeylove Save 20% Off Honeylove by going to https://www.honeylove.com/neuro. Cowboy Colostrum Get 25% Off with code NEURO at https://www.cowboycolostrum.com. AquaTru Go to https://www.AquaTru.com now for 20% off (your purifier) using promo code NEURO. AquaTru even comes with a 30-day best-tasting water guarantee.  Brickhouse Nutrition Get 20% off when you enter NEURO at https://www.takelean.com. *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Follow Dr. Alicia Robbins The Elm: https://theelmgreenwich.com/ Instagram: @aliciarobbinsmd Topics discussed: 00:00:00 — Intro 00:01:32:10 — Menopause is “in the spotlight”; what’s actually happening with women’s hormones ~35+ 00:02:43:11 — Ovaries as the primary source of estrogen/progesterone/testosterone 00:11:32:08 — Estrogen’s role in the brain 00:13:15:05 — With estrogen loss, chronic low-grade brain inflammation 00:15:12:17 — What replaced HRT: rise in sleep aids, antidepressants, and benzodiazepines. 00:32:55:20 — Women’s testosterone: low “total T” numbers, variable symptoms/benefit; brain fog and fatigue are multifactorial. 00:33:38:00 — Practical regimen notes: layering hormones; balance affected by stress/cortisol 00:44:14 — Longevity hype vs reality: trendy biohacks vs basics like walking, resistance training, and consistent diet 00:44:34 — Cultural/societal neglect of women’s midlife health; undervaluing cognitive preservation in women 00:45:10 — Lack of specialty in menopause medicine; OB/GYN training gaps; bias toward fertility/pregnancy funding 00:47:20 — Emerging shift: younger physicians and social media spreading awareness 00:48:15 — Longevity basics reaffirmed: lifestyle interventions are more impactful than costly interventions 00:49:00 — Empowering women to advocate for care 00:50:12 — Future outlook: preventative care, lifestyle foundations, and individualized hormone therapy for healthy aging 00:54:53: Increase in divorce rate because of hormones? 00:55:53: HRT and risk of breast cancer 00:58:11: What doctor should a woman in her late 30s/early 40s go see? Learn more about your ad choices. Visit megaphone.fm/adchoices

Most of us think protein is just about building muscle—but what if we’ve been getting it wrong all along? In this eye-opening episode, host Louisa sits down with Angelo Keely, co-founder and CEO of Kion, to uncover the real science behind protein, amino acids, and muscle health. Angelo explains why essential amino acids—not just protein—are the critical drivers of muscle maintenance, recovery, and even longevity. He breaks down the shocking truth about how different protein sources actually compare, why aging adults need more than the RDA suggests, and how supplements like amino acids can prevent muscle loss—even without exercise.  Whether you’re a midlife woman trying to protect bone density, an athlete looking for an edge, or simply someone who wants to age stronger—this is an episode you can’t afford to miss. About the guest: Angelo is the co-founder and CEO of Kion, a lifestyle and supplement company built around optimizing health and energy through essential nutrients. With a lifelong passion for nutrition and performance, he’s on a mission to educate people about the powerful science of amino acids and help them live stronger, healthier, and longer lives.  Discover Kion: Instagram: @kion Visit getkion.com/neuro for 20% off. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: OSEA  Get 10% off your first order sitewide with code NEURO at OSEAMalibu.com. You’ll get free samples with every order, and free shipping on orders over $50.  Ketone IQ Go to www.ketone.com/NEURO for 30% OFF your subscription order + receive a free gift with your second shipment. Wildgrain For a limited time, Wildgrain is offering my listeners $30 off the first box - PLUS free Croissants in every box - when you go to Wildgrain.com/NEURO to start your subscription.  Cozy Earth Head to cozyearth.com and use my code NEURO for 40% off! Cowboy Colostrum For a limited time, our listeners get 25% off their entire order. Head to CowboyColostrum.com and use code NEURO at checkout.  Puori Go to puori.com/NEURO and use the code NEURO at checkout for 20% off *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed:00:00:00 - Intro 00:01:33 - confusion around protein, fat loss 00:02:36 - Carbs/fat = fuel vs protein = structure; macronutrient primer  00:04:29 - Protein turnover & amino acids (house remodel analogy)  00:08:29 - Protein beyond muscle00:11:02 - Energy storage vs “amino reservoir”; why low protein costs muscle  00:13:25 - Nuance in intake advice; social/media oversimplification00:17:18 - “Protein isn’t equal” 00:18:27 - What EAAs are; “essential” vs “non-essential”; leucine as trigger  00:21:15 - Comparing foods: plant vs dairy/eggs vs. meat 00:25:05 - Protein potency ladder 00:27:15 - Louisa’s protein plan; bioavailability clarification; why EAAs hit faster 00:30:28 - Aging & leucine-enriched EAAs 00:35:22 - Steak “not very anabolic” alone; training vs nutrition  00:36:11 - NASA bed-rest studies 00:38:09 - Building muscles with amino acids and no exercise controversy  00:40:46 - Angelo’s backstory & founding Kion 00:43:31 - Practical playbook (midlife female) 00:50:08 - GLP-1 weight-loss caveat Learn more about your ad choices. Visit megaphone.fm/adchoices

Women can lose up to 20% of their bone density during perimenopause—and most don’t even know it’s happening. In this episode, orthopedic surgeon and author Dr. Vonda Wright breaks down how aging, hormones, and lifestyle impact bone, muscle, and brain health, and shares practical steps to stay strong, resilient, and unbreakable. From hormone therapy to lifting weights, she reveals the science-backed strategies that help women thrive at every stage of life. About the guest: Dr. Vonda Wright is a double-boarded orthopedic surgeon and leading authority on active aging and mobility. Her practice spans minimally invasive hip, shoulder, and knee surgery, cartilage restoration, injury prevention, and performance optimization. As founding director of PRIMA, her groundbreaking research on musculoskeletal aging is reshaping how we approach longevity and mobility. Dr. Wright has cared for athletes across the spectrum—from Division I teams and Olympic track athletes to World Rugby, the Atlanta Ballet, and even E-Sports competitors. *** Where to find Dr. Vonda Wrighthttps://www.drvondawright.com/ Instagram: @drvondawright Pre-order her new book: https://theunbreakablebook.com/ *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Function Health: Visit www.functionhealth.com/Louisanicola or use gift code NEURO100 at sign-up to own your health. Ketone IQ: Go to https://ketone.com/NEURO for 30% OFF your subscription order + receive a free gift with your second shipment. *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00 – Intro 01:15 – Aging, Hormones & Bone Density after 30 05:35 – Defining Frailty & “Unbreakable” 09:15 –  Underlying message & Practice Insights 13:54 - Muscle vs. Sedentarism 17:00 – Bone as an Organ 20:00 Bone Hormones & Brain Health 27:00 - Osteoporosis Risks & Prevention 32:20 Bone Quality vs. Density 37:23 – Estrogen, Inflammation & Musculoskeletal Aging 46:09 – Personal Story of Perimenopause 51:03 – Politics of Women’s Health 1:07:00 – Supplements for Bone Health Learn more about your ad choices. Visit megaphone.fm/adchoices

What if your bleeding gums could be the reason you can’t get pregnant—or why your brain is at risk of Alzheimer’s? In this groundbreaking conversation with functional dentist Dr. Staci Whitman, we uncover how your oral microbiome impacts far more than just your smile. From fertility struggles and pregnancy loss to Alzheimer’s, cancer, and even depression, the bacteria in your mouth may be silently shaping your entire health span. Dr. Whitman breaks down the science of “leaky gums,” reveals why saliva is the body’s golden elixir, and explains how simple shifts in diet, hygiene, and oral microbiome testing could change the future of medicine. This is not just about teeth—it’s about your brain, hormones, longevity, and life itself. About Dr. Staci Whitman: Dr. Staci Whitman is a board-certified pediatric dentist and founder of NoPo Kids Dentistry in Portland, Oregon, where she practices a whole-body, functional approach to children’s oral health. A graduate of Tufts University and OHSU, she has specialized expertise in sleep, airway health, and myofunctional therapy. Dr. Staci is also a Diplomate of the American Board of Pediatric Dentistry, a Breathe Institute Ambassador, and an active member of several holistic and biological dentistry organizations. Her mission is simple yet powerful: to create a world without cavities and to empower families with practical, science-backed tools for lifelong health. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Function Health: Learn more and join using our/my link. The first 1000 get a $100 credit toward their membership. Visit www.functionhealth.com/louisanicola and use code NEURO100 or use gift code NEURO100 at sign-up to own your health. Boncharge: Go to www.boncharge.com | Code: NEURO15 for 15% off FIGS: You can get 15% off your first order at https://wearfigs.com with the code FIGSRX. Manukora: Head to www.manukora.com/neuro to save up to 31% plus $25 worth of free gifts with the Starter Kit. Cozy Earth Head to cozyearth.com and use my code NEURO for 40% off! Rula Go to Rula.com/NEURO to get started today. For convenient therapy that’s covered by insurance. *** I’m Louisa Nicola — clinical neurophysiologist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00:00 Oral health, gum disease & fertility connection 00:02:46 Inflammation & systemic effects 00:06:00 Defining true oral health (nutrition, saliva, airway) 00:08:25 Diet, processed foods & cavities 00:15:00 Saliva, dry mouth & gut health 00:19:49 Oral microbiome testing & treatments 00:24:17 Treatment plan, family transmission & genetics 00:26:30 Alzheimer’s, brain health & strokes 00:33:07 Oral health & cancer links 00:41:50 Inflammation causing pancreatic cancer 00:42:27: Failing dental work and cancer 00:43:37: Fertility & Menopause 00:46:31 Spit test & depression/mood disorders 00:48:39 Oral health toolkit & practical hygiene tips Learn more about your ad choices. Visit megaphone.fm/adchoices

What if your bleeding gums could be the reason you can’t get pregnant—or why your brain is at risk of Alzheimer’s? In this groundbreaking conversation with functional dentist Dr. Staci Whitman, we uncover how your oral microbiome impacts far more than just your smile. From fertility struggles and pregnancy loss to Alzheimer’s, cancer, and even depression, the bacteria in your mouth may be silently shaping your entire health span. Dr. Whitman breaks down the science of “leaky gums,” reveals why saliva is the body’s golden elixir, and explains how simple shifts in diet, hygiene, and oral microbiome testing could change the future of medicine. This is not just about teeth—it’s about your brain, hormones, longevity, and life itself.About Dr. Staci Whitman: Dr. Staci Whitman is a board-certified pediatric dentist and founder of NoPo Kids Dentistry in Portland, Oregon, where she practices a whole-body, functional approach to children’s oral health. A graduate of Tufts University and OHSU, she has specialized expertise in sleep, airway health, and myofunctional therapy. Dr. Staci is also a Diplomate of the American Board of Pediatric Dentistry, a Breathe Institute Ambassador, and an active member of several holistic and biological dentistry organizations. Her mission is simple yet powerful: to create a world without cavities and to empower families with practical, science-backed tools for lifelong health. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Function Health: The first 1000 get a $100 credit toward their membership. Visit www.functionhealth.com/louisanicola and use code NEURO100 or use gift code NEURO100 at sign-up to own your health. Boncharge: Go to www.boncharge.com | Code: NEURO15 for 15% off FIGS: You can get 15% off your first order at https://wearfigs.com with the code FIGSRX.  Manukora: Head to www.manukora.com/neuro to save up to 31% plus $25 worth of free gifts with the Starter Kit. Cozy Earth Head to cozyearth.com and use my code NEURO for 40% off!  Rula Go to Rula.com/NEURO to get started today. For convenient therapy that’s covered by insurance.  *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00:00 Oral health, gum disease & fertility connection 00:02:46 Inflammation & systemic effects 00:06:00 Defining true oral health (nutrition, saliva, airway) 00:08:25 Diet, processed foods & cavities 00:15:00 Saliva, dry mouth & gut health 00:19:49 Oral microbiome testing & treatments 00:24:17 Treatment plan, family transmission & genetics 00:26:30 Alzheimer’s, brain health & strokes 00:33:07 Oral health & cancer links 00:41:50 Inflammation causing pancreatic cancer 00:42:27 Failing dental work and cancer 00:43:37 Fertility & Menopause 00:46:31 Spit test & depression/mood disorders 00:48:39 Oral health toolkit & practical hygiene tips Learn more about your ad choices. Visit megaphone.fm/adchoices

This week, I am joined by Ben Bruno—a Los Angeles–based trainer whose client roster ranges from professional athletes to musicians, actors and models. Known for his no-nonsense approach, Ben believes that while every person is different, the principles of good training remain the same: simple, consistent, and effective work tailored to the individual. In this conversation, Ben cuts through the noise of social media fitness trends and breaks down what really works for building strength, staying mobile, and aging well. With nearly two decades of experience, he’s trained stars like Jessica Biel and Chelsea Handler, yet his message applies to anyone with a goal, a positive attitude, and the willingness to work hard. In this episode, Ben Bruno shares why consistency and the basics always outperform flashy trends, and how real-world training differs from what we see online. He breaks down the three pillars of longevity—strength, mobility, and conditioning—explains why full-body workouts often work best, and highlights the key exercises everyone should master. Ben also dives into how women can stay strong and confident into midlife, the dangers of comparison culture, and why sustainable, smart training beats gimmicks every time. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Function Health: Learn more and join using our/my link. The first 1000 get a $100 credit toward their membership. Visit ⁠www.functionhealth.com/louisanicola⁠ and use code NEURO100 or use gift code NEURO100 at sign-up to own your health. Troscriptions: Go to www.troscription.com/neuro | Code: NEURO for 10% your first order  Ketone IQ:  Go to https://ketone.com/NEURO for 30% OFF your subscription order + receive a free gift with your second shipment. Timeline: Head to timeline.com/neuro to get 20% off Beam: Visit https://shopbeam.com/TNE and use code TNE to get our exclusive discount of up to 35% off Honeylove: Save 20% Off Honeylove at honeylove.com/NEURO ***Where to find Ben Bruno Instagram: benbrunotraining Twitter: @benbruno1 Fitness app: https://benbruno.com/start/ *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00: Consistency over quick fixes; Jessica Biel & Chelsea Handler’s long-term training 05:18: Social media fitness vs. real-world training; flashy trends vs. basics 07:18: Longevity & aging 11:09: Full-body training vs. body-part splits; flexibility & practicality 14:11: Unrealistic fitness standards 20:05: Nutrition & biohacking noise 26:05: Exercise dose & sustainability: overtraining risks, exercise as medicine 29:00: Men vs. women in training; goals vs. needs; injury considerations 35:00: Progressive overload, RPE (rate of perceived exertion), strength testing 42:07 : Essential exercises: Bulgarian split squat, chin-ups (vs. squats/deadlifts) 44:11: Core training, injury prevention, importance of rotational strength Learn more about your ad choices. Visit megaphone.fm/adchoices

In this powerful and eye-opening conversation, I sit down with the founders of WeNatal, a company redefining preconception health for both women and men. Together, we dive into the overlooked science of Trimester Zero—the 3 - 4 months before trying to conceive—and why this time frame can be a game-changer for both natural conception and IVF outcomes. This episode breaks down the science, dispels myths, and provides tangible, realistic steps you can take to optimize your fertility—without the stress of perfectionism. We also unpack why the conversation around fertility needs to shift from being a “women’s health” issue to a team sport. About the WeNatal Founders: After experiencing miscarriages just a week apart, best friends Vida and Ronit were left devastated and searching for answers. Despite being healthy and on prenatal vitamins, doctors dismissed their losses as “random” or “age-related.” Digging deeper, they discovered a missing piece in fertility care: men’s health. Determined to change that, they partnered with experts, pored over research, and created a science-backed prenatal system for both women and men. What began as a personal mission has grown into WeNatal—a movement giving couples the knowledge, tools, and products to support conception, pregnancy, and the lifelong health of future generations. *** Get a free month of WeNatal’s Rest + Digest magnesium when you subscribe today at wenatal.com/neuroexperience *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Boncharge: Go to https://boncharge.com | Code: NEURO15 for 15% off Caraway: https://caraway.com/neuro for an additional 10% off your purchase LMNT: Use code drinklmnt.com/neuro to get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase. Thrive Market: Go to ThriveMarket.com/neuro to get 30% off your first order, and a free $60 gift. OSEA: Get 10% off your first order site wide with code NEURO at https://OSEAMalibu.com. You’ll get free samples with every order, and free shipping on orders over $50. *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Topics discussed: 00:00:00 — The #1 thing ruining women’s fertility 00:03:09 — Trimester Zero: preconception importance00:05:14 — Male fertility: sperm quality & regeneration 00:06:42 — Epigenetics & passing traits to children 00:08:36 — Role of mitochondria in egg quality 00:10:46 — Myth-busting egg quantity vs. quality & aging 00:12:07 — Environmental changes & food nutrient depletion 00:17:10 — Plastics, toxins & lifestyle adjustments 00:21:25 — AMH (Anti-Müllerian Hormone) misconceptions 00:28:08 — Fertility industry concerns & preparing for conception 00:32:01 — Biological vs. chronological age in fertility 00:38:09 — IVF, diet changes & improved outcomes 00:42:01 — Key supplements: CoQ10, PQ, omega-3s 00:48:48 — Supplement regulation & quality control Learn more about your ad choices. Visit megaphone.fm/adchoices

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In this episode, I sit down with Dr. Rupy Aujla, an NHS GP and the founder of The Doctor’s Kitchen, an app that includes doctor-approved recipes to cook at home. In this conversation, we dive into why cardiovascular disease remains the #1 killer worldwide, the connection between cholesterol and heart health, how fiber acts as a “magical nutrient” for the body, how to introduce it into your daily meals, and the role of lifestyle choices in preventing illness and supporting long-term brain and heart health. *** About Dr. Rupy Aujla: After suffering a significant heart condition, he dove deep into the science of nutritional medicine and was able to reverse his condition through food and lifestyle. In 2015, he launched The Doctor’s Kitchen as a way to teach people how to cook their way to better health and to showcase the medicinal effects of eating well. The incredible “Doctor’s Kitchen” cooking app has over 1000 delicious, science-backed recipes and 20 brand new ones added each month. There’s also a handy meal planner that will personalise recipes based on your preferences. It actually suggested a delicious looking salmon poached in harissa coconut sauce, and  olive and date braised chicken, which suit my personal dietary needs and all sound great. You can download and use the app completely for free using this link. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: David’s Protein: Buy four cartons and get your fifth one completely free | Head to https://davidprotein.com/pages/neuro Ketone IQ: Go to https://ketone.com/NEURO for 30% OFF your subscription order + receive a free gift with your second shipment. FIGS: You can get 15% off your first order at https://wearfigs.com with the code FIGSRX. Caraway: https://caraway.com/neuro for an additional 10% off your purchase MUD\WTR: The coffee alternative. If you're ready to ditch the crash and sip smarter, go to https://mudwtr.com and use code NEURO to get 43% off + free shipping. *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ *** Topics: 00:02:43: Lipid panels & overlooked markers 00:05:21: Atherosclerosis explained 00:08:13: Misleading “normal” cholesterol panels 00:10:48: Why heart disease remains #1 killer & prevention timeline 00:12:51: Cholesterol & Alzheimer’s; LDL targets for brain health 00:15:12: Cholesterol causality, very low LDL safety 00:19:23: Statins & pharmacological interventions 00:26:02: Ultra-processed foods & saturated fats 00:29:26: Fiber’s role in lowering LDL 00:32:05: How fiber binds bile acids & removes cholesterol 00:33:29: Gut microbiome & short-chain fatty acids from fiber 00:35:05: Lowering ApoB, LDL by eating plant-rich foods, portfolio diet 00:37:15: Oats & heart health 00:41:51: Pesticides in fruits and vegetables 00:45:37: Eggs and cholesterol 00:48:18: Soy 00:53:55: Balanced eating 00:57:40: Stress, sleep & cardiovascular disease 00:59:55: Memorable patient stories, family member with stent 01:04:04: How to reduce risk of heart attack or stroke with diet Learn more about your ad choices. Visit megaphone.fm/adchoices

Is Zone 2 cardio really the key to longevity and fat loss—or have we been misled? In this solo episode, Louisa challenges the fitness status quo and reveals why low-intensity steady-state cardio might be wasting your time—especially if you're a woman. Drawing on new 2025 research and her deep background in exercise physiology, Louisa explains how men and women respond differently to training, and why higher-intensity workouts may be far more effective for improving mitochondrial health, brain aging, VO2 max, and metabolic flexibility. If you're a woman in your 30s, 40s, 50s, or 60s trying to optimize your longevity, brain function, and body composition—this is a must-listen.  True optimization and longevity never come from comfort alone. You'll learn: Why Zone 2 may not improve mitochondrial health like you think The real training zones that boost VO2 max, fat oxidation & brain function How perimenopausal and menopausal women must train differently The exact weekly routine to optimize longevity, body comp & cognition *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Troscriptions: Head to www.troscription.com/neuro | Code: NEURO for 10% your first order Boncharge: Head to www.boncharge.com | Code: NEURO15 for 15% off Ketone IQ: Head to www.ketone.com/NEURO for 30% OFF your subscription order + receive a free gift with your second shipment. Manukora: Head to www.manukora.com/neuro to save up to 31% plus $25 worth of free gifts with the Starter Kit. *** I’m Louisa Nicola — clinical neuroscientist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ *** Topics discussed: 00:00:00: Exercising in zone 2 is a waste of time 00:00:43: Research that shifted her views, especially for women 00:01:41: What Is Zone 2? – Definition and physiology explained 00:02:17: Zone 2 in Practice – How it's measured in real-world settings  00:03:23: Comfort Zone Training – Why Zone 2 is easy but not effective  00:04:16: Elite Athletes vs. The Rest of Us 00:05:10: Why intensity matters more 00:08:11: Time efficiency and real-life experience 00:09:23: Brain Health & Mitochondria – Higher intensity for cognition  00:10:15: Why Zone 2 doesn’t have special signaling power  00:12:25: Why higher zones burn fat better  00:13:35: Zones 1 through 5 explained 00:14:00: Zone 5: The Death Zone 00:15:18: Menopause & Muscle Fibers  00:16:55: Lactate Fuels the Brain 00:18:11: How to Train for Longevity – Resistance, intensity, and logic 00:23:59: VO2 Max   00:26:40: Norwegian 4x4 and weekly training strategy  00:30:00: Resistance Training 101 – 5x5 sets, compound lifts, and strength focus  00:31:38: Zone 2 as Recovery – When and how to actually use it 00:33:07: Final Takeaway – Zone 2 isn’t bad, but it shouldn’t be your priority  Learn more about your ad choices. Visit megaphone.fm/adchoices

In this powerful episode, I sit down with Dr. Jeremy London—a board-certified cardiothoracic surgeon with over 26 years of experience—to uncover the often-overlooked truths about cardiovascular disease, especially in women. Dr. London shares why menopausal women face triple the risk for heart disease, and what you can do to protect yourself. From the life-saving power of simply moving your body to the three essential tests everyone should be asking for, this conversation breaks down complex health topics into clear, actionable steps. Whether you’re navigating midlife or looking to take preventative measures, this episode is a must-listen for anyone ready to take control of their heart health. About Dr. Jeremy London: Dr. Jeremy London is a Board-Certified Cardiothoracic Surgeon with over 26 years of clinical experience. He earned his medical degree from the Medical College of Georgia and completed his surgical training in Denver and Charlotte. A passionate advocate for patient education, Dr. London is on a mission to make health information more accessible through his newsletter, podcast, and social media. He lives in Savannah, Georgia with his wife and their three sons. *** Subscribe to The Neuro Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. *** A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Caraway: www.caraway.com/neuro for an additional 10% off your purchase LMNT:Use code drinklmnt.com/neuro to get a free 8-count Sample Pack of LMNT’s most popular drink mix flavors with any purchase. MUD\WTR - The coffee alternative. If you're ready to ditch the crash and sip smarter, go to mudwtr.com and use code NEURO to get 43% off + free shipping. David’s Protein: Buy four cartons and get your fifth one completely free | Head to www.davidprotein.com/neuro Branch Basics: www.branchbasics.com to shop their Premium Starter Kit and save 15% | Code: NEURO *** Topics discussed: 00:00:00: Why women’s cardiovascular risk triples after menopause 00:03:40: Two out of three Alzheimer’s disease patients are women 00:04:47: What are lipid panels 00:05:20: Cardiovascular disease is the number one cause of death worldwide 00:06:13: The three buckets of heart disease 00:07:27: Cholesterol 00:08:47: ApoB 00:10:15: Plaque 00:10:53: Lp(a) 00:14:39: Louisa’s mother’s lab results 00:16:09: Going beyond lab work: Screen tests 00:17:39: Cardiac catheterization 00:19:49: Carotid ultrasound 00:21:07: What is atrial fibrillation and how is it diagnosed? 00:26:37: What you can do yourself to diagnose Afib 00:31:14: What was COVID like in the cardiovascular department? 00:35:47: Blood pressure 00:41:48: AI in the medical field 00:48:07: Exercise to minimize risk of cardiovascular disease 00:53:21: Healthy nutrition to minimize risk of cardiovascular disease 00:55:01: Can supplement eliminate plaque? 00:56:09: Changing our lifestyle and diet to mitigate diseases 00:57:31: Sleep quality to minimize risk of cardiovascular disease *** I’m Louisa Nicola — clinical neurophysiologist — Alzheimer’s prevention specialist — founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain — reducing Alzheimer’s risk — and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices