The Toxpod

The Toxpod

Forensic Toxicology: It's a matter of half-life and death

5 in 30 (Chemometrics, single hair analysis and GC-VUV)

We look at 5 recent publications in the field of toxicology. Polettini A, et al. LC–QTOF-MS Presumptive Identification of Synthetic Cannabinoids without Reference Chromatographic Retention/Mass Spectral Information. II. Evaluation of a Computational Approach for Predicting and Identifying Unknown High-Resolution Product Ion Mass Spectra. (2021) Journal of Analytical Toxicology, 45(5):440-61.Kuwayama, K. et al. Development of the “selective concentration” analytical method for drug-containing ...

06-22
36:01

New Psychoactive Substances with Alex Krotulski

We chat with Alex Krotulski about his work with CFSRE and NPS Discovery. You can find out more about these initiatives, and access the many resources they produce, at https://www.npsdiscovery.org/ Contact us at toxpod@tiaft.org Find out more about TIAFT at www.tiaft.org The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT. You can send us a text message...

06-15
35:59

Are toxicologists too sensitive?

Modern forensic toxicologists are able to detect tiny amounts of drugs in a sample. Is it possible we are now too sensitive?Contact us at toxpod@tiaft.orgFind out more about TIAFT at www.tiaft.orgThe Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.You can send us a text message using this link!

06-08
29:37

Reference Standards with Jenny Button

We chat with Jenny Button, Deputy Director of Chiron, about the use of reference standards in forensic toxicology. Jenny's written a book chapter about all this - it's really good! Here's a link. Contact us at toxpod@tiaft.org Find out more about TIAFT at www.tiaft.org The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT. You can send us a text message usi...

06-01
35:43

Activity Based Assays with Marthe Vandeputte

Tim chats with Marthe Vandeputte about the current and potential uses of activity based assays in forensic toxicology. Links to a couple of Marthe's papers on the topic are below: Validation of activity-based screening for synthetic cannabinoid receptor agonists in a large set of serum samples In vitro functional characterization of a panel of non-fentanyl opioid new psychoactive substances Contact us at toxpod@tiaft.org Find out more about TIAFT at www.tiaft.org The Toxpod is a production...

05-25
33:17

5 in 30 (Impairment apps, zebrafish and Scottish prisons)

We look at 5 recent publications in the field of toxicology. Karoly, H. et al. Effects of high-potency cannabis on psychomotor performance in frequent cannabis users. (2020) Cannabis and Cannabinoid Research, X:X, 1-9Prado, E. et al. Metabolism of synthetic cathinones through the zebrafish water tank model: a promising tool for forensic toxicology laboratories. (2021) Forensic Toxicology, 39: 73-88Chu, M. et al. Time-dependent changes in THC concentrations in deceased persons. (2021) Journal ...

05-18
37:33

Cognitive Bias with Hilary Hamnett

We chat with Hilary Hamnett about the complex issue of cognitive bias in forensic toxicology. If you'd like to hear more from Hilary about cognitive bias, you can contact her at HHamnett@lincoln.ac.uk Contact us at toxpod@tiaft.org Find out more about TIAFT at www.tiaft.org The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT. You can send us a text messa...

05-11
37:38

Positively negative

How confident are you that your analytical methods won't miss a target analyte? In the first episode of season 4, we discuss the potential for false negative results in forensic toxicology. Contact us at toxpod@tiaft.org Find out more about TIAFT at www.tiaft.org The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT. You can send us a text message usin...

05-04
31:58

5 in 30 (Fingerprints, SWATH and retrospective screening)

We look at 5 recent publications in the field of toxicology. Costa, C. et al. Distinguishing between contact and administration of heroin from a single fingerprint using high resolution mass spectrometry. (2020) Journal of Analytical Toxicology. 44: 218-225Kaufmann, A. et al. Partially overlapping sequential window acquisition of all theoretical mass spectra: A methodology to improve the spectra quality of veterinary drugs present at low concentrations in highly complex biological matrices. (...

06-16
38:55

Workplace testing with Alberto Salomone

Tim chats with Alberto Salomone about workplace testing, hair analysis, and new psychoactive substances. Contact us at toxpod@tiaft.orgFind out more about TIAFT at www.tiaft.orgThe Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.You can send us a text message using this link!

06-09
38:22

Drugs in wastewater with Richard Bade

Peter chats with Richard Bade about the advantages and challenges of wastewater analysis.Contact us at toxpod@tiaft.orgFind out more about TIAFT at www.tiaft.orgThe Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.You can send us a text message using this link!

06-02
25:04

Vaping with Michelle Peace

Tim chats with Michelle Peace about her current research on vaping, and her experiences in the field of forensic toxicology.Contact us at toxpod@tiaft.orgFind out more about TIAFT at www.tiaft.orgThe Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.You can send us a text message using this link!

05-26
37:42

Drafting an analytical method

We channel our sports withdrawal into a toxicology related draft.Thanks to Michaela Kenneally and Stephen Trobbiani for participating in this episode.Contact us at toxpod@tiaft.orgFind out more about TIAFT at www.tiaft.orgThe Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.You can send us a text message using this link!

05-19
32:54

CAT conference 2020

The California Association of Toxicologists Spring meeting has been postponed due to COVID restrictions, but that won't stop us from chatting with some of the planned speakers! Thanks to Luke Rodda, Jarrad Wagner, Juliet Kinyua and Alan Wu for participating in this episode. Contact us at toxpod@tiaft.org Find out more about TIAFT at www.tiaft.org The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and d...

05-12
39:35

Synthetic Cannabinoids with Samuel Banister

We talk about synthetic cannabinoids (or is that SCRAs?) with medicinal chemist Samuel Banister. Contact us at toxpod@tiaft.orgFind out more about TIAFT at www.tiaft.orgThe Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the views of TIAFT.You can send us a text message using this link!

05-05
36:26

5 in 30 (Isotonitazene, wastewater and MS interferences)

We look at 5 recent publications in the field of toxicology. Blanckaert, P. et al. Report on a novel emerging class of highly potent benzimidazole NPS opioids: Chemical and in vitro functional characterization of isotonitazene. (2020) Drug Testing and Analysis. 12: 422-430Reinstadler, V. et al. A validated workflow for drug detection in oral fluid by non-targeted liquid chromatography-tandem mass spectrometry. (2019) Analytical and Bioanalytical Chemistry. 411:867-876Benaglia, L. et al. Testi...

04-28
38:47

Season 3 preview

Season 3 drops on April 29. Subscribe now!You can send us a text message using this link!

04-21
01:11

5 in 30 (Ayahuasca, metabolomics and bone marrow)

In our last episode of the season, we look at 5 recent publications in the field of toxicology.Steuer, A. et al. Identification of new urinary gamma-hydroxybutyric acid markers applying untargeted metabolomics analysis following placebo-controlled administration to humans. (2019) Drug Testing and Analysis. 11 (6):813-823Souza, R. et al. Validation of an analytical method for the determination of the main ayahuasca active compounds and application to real ayahuasca samples from Brazil. (2019) ...

10-08
36:42

When is a Drug Not a Drug?

In this episode, we dive into the techniques, practices, and guidelines used in forensic toxicology for drug identification. Do we have the balance right? Some of the available identification guidelines: World Anti-Doping Agency (WADA) European Workplace Drug Testing Society (EWDTS) Organisation of Scientific Area Committees (OSAC) Gesellschaft für Toxikologische und Forensische Chemie (GTFCh) That article Pete mentioned on amphetamine isomers: Brown, D. H., et al. (2016). "Beta-methylpheny...

10-01
35:42

On the Spot at TIAFT2019

During his recent trip to the TIAFT2019 conference in Birmingham, England, Peter caught up with a few toxicologists to discuss some of their recent work. Barry Logan's group has published their findings on kratom Join the HighResNPS community Contact us at toxpod@tiaft.org Find out more about TIAFT at www.tiaft.org The Toxpod is a production of The International Association of Forensic Toxicologists. The opinions expressed by the hosts are their own and do not necessarily reflect the vie...

09-24
29:03

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