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The Trip Lab
The Trip Lab
Author: Mary Ella Wood, DO
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© 2025 The Trip Lab
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Welcome to The Trip Lab, kitchen table conversations about integrative medicine and psychedelics with your host and attending physician, Dr. Mary Ella Wood. Taking an evidenced-based approach, we will break down the latest research, interview leaders in the field, and answer all the questions that don't often get brought up in the doctor's office. Instagram: @thetriplabpodcast - Email: thetriplabpodcast@gmail.com
18 Episodes
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In this season 2 opening episode of The Trip Lab, I return from maternity leave with a deeply personal exploration of how psychedelic experiences mirror one of the most profound transitions in a woman’s life: motherhood. From the sudden crash of postpartum hormones to the full dissolution of identity and the slow reconstruction of self, I reflect on how becoming a mother felt strikingly similar to a psychedelic journey — raw, disorienting, expansive, and sacred. We dive into the neuroscience ...
Osteopathic manipulative treatment (OMT) is a hands on diagnostic and treatment modality that DOs learn in medical school. You may have seen the DO (rather than MD) after your doctor's name and never really understood what that meant. We dive into the difference between MDs and DOs and talk all about what osteopathic medicine is in this episode. Many OMT treatments actually mirror what a yoga practice can do for you as well. Whether we are talking about the poses (or asanas) creating simult...
Today I will be introducing a new 'deep dive series' on The Trip Lab. We are going to be looking into the most common medical conditions to really understand what is happening in the body and how they develop. With that understanding, we can better understand how our treatments work-- including pharmaceuticals and surgery as well as integrative therapies like herbal medicine and mind-body medicine. To start this series, we will look at how this divide between 'modern' medicine and 'alt...
This episode is going to be a high level overview over all of the primary causes of anxiety and depression, and integrative approaches to treat them. Anxiety and depression is a lot more complicated than just writing a script for sertraline or recommending therapy. These disorders definitely have a psychological component that can stem from chemical imbalances in the brain... but other causes include nutritional deficiencies, inflammation and adrenal fatigue, poor sleep hygiene, not exercis...
Today we interview UCSF psychiatrist Emily Willow, MD. She has a robust career in psychedelic medicine and has worked on clinical trials using MDMA, psilocybin and ketamine. Currently, she has a private practice where she does ketamine assisted psychotherapy and psychedelic integration therapy. We chat all about her experience using these different psychedelic compounds, and the benefits and cautions of each depending on what each patient is trying to heal. We also discuss cognitive liberty...
A Trip Lab Thought Experiment: We will dive into an alternate reality where psychedelics can be used by anyone to explore their consciousness and place in the world (without having a mental health disorder like depression to make it legal). Find out how psychedelics can help you understand the complex topics of quantum physics, string theory, the illusion of time and parallel universes. We will also discuss exciting new research papers looking into how psychedelics have been proven to inc...
We chat with Dr. Mark Braunstein about how he pioneered a new path in psychiatric care using cannabis, ketamine and psilocybin... in addition to integrating wilderness programming, exercise, diet and spirituality to treat depression, addiction, anxiety and trauma. He dives deeper into how cannabis works in the mind and the different ways he prescribes this to his patients. We also chat about the future of cannabis and psychedelic medicine-- both seeing it as an exciting opportunity to treat p...
Chronic low levels of inflammation is linked to at 8 out of the 10 leading causes of death in the United States. This, along with chronic stress, causes premature aging, cardiovascular disease, neurodegenerative disease, cancer and a lot more. This episode dives deeper into how this process happens... and what you can change in your diet to combat it. This episode rounds out our discussion on inflammation and stress, following episode #6 all about adaptogenics and the HPA access ...
Mia Cara Cosco is the Creative Director of Psychedelic Salons. She has 10 years of experience in psychedelic medicine advocacy and has a really beautiful take on these plants and fungi as medicine. We chat all about the work that she does holding space for people to experience psychedelics, as well as creating spaces to merge social venture capital with artists, business people, leaders and visionaries. Mia is passionate about 'democratizing cognitive liberation' with psychedelics and...
Max C Wood is a graduate student studying developmental neuroscience and psychopathology at the Anna Freud Center in London. He is finishing his studies at Yale, studying the impact that attachment styles have on a psychedelic treatment design, using ketamine. We talk all about how developmental neuroscience came to be, and why this goes hand in hand with understanding the brain using psychedelics... in addition to using psychedelics to treat human suffering. Going a little deeper int...
Mind-Body Medicine was until recently, dismissed by modern medicine. The idea that the mind could influence the body was paradoxically deemed just not true--- it's no surprise the current data is saying otherwise. It is know widely accepted that increased stress experienced in the mind lowers the immune system and influences a wide variety of disease, most notably cardiac and metabolic. In this episode we break down the autonomic nervous system (to round out the neurological side of the str...
Adaptogenics and nootropics have become buzzwords in posh grocery stores-- on every botanical elixir and new sparkling water. But what exactly are they? Do they actually work? And what does the data tell us? Find it all out in the episode! Adaptogenic herbs: panax ginseng, rhodiola, ashwaganda, licorice root, milk thistle Adaptogenic mushrooms: maitake, reishi, cordyceps, lion's mane Adaptogenic foods: ginger, garlic, green tea Nootropics mentioned: caffeine, GABA, L-theanine Mentions Chic...
The benefits of yoga have been proven extensively in the medical literature. We dive into the science of how yoga works to treat mental health disorders, musculoskeletal disorders, cardiovascular disease and even the cognitive decline that comes with age. Then, for our very first guest interview we have Shelby Caldwell here to answer all of our yoga questions. She is a certified yoga instructor and currently manages the Ritual Hot Yoga Studio in Chicago. We have an open and honest conve...
This episode is going to be all about MDMA (also known as Molly or Ecstasy). We will explore the history of this compound and it's use, the neuroscience of how it works, what the latest clinical trials have shown, and even look at the shadow side of these sort of therapy sessions. Mentioned Links: Netflix Docuseries: 'The Business of Drugs' Book: ‘The Gateway of the Heart: Accounts of Experiences with MDMA and other Empathogenic Substances’ compiled and edited by Sophia Adamson
An overview of magic mushrooms and LSD (aka Acid). We will chat about the history of these compounds, why they were banned, why they are making a comeback, and how they are being used to treat anxiety, depression, addition and so much more. We will explain the neuroscience in an easy to understand way, and what this might mean for the future of psychiatry (and just life!). Book: 'The Immortality Key' by Brian C. Muraresku New Neuronal Connections Depiction
What actually is integrative medicine? How does it differ from 'alternative' or 'naturopathic' medicine? When should you see an integrative medicine doctor? All of your questions answered below. 0:45 - What is integrative medicine? 3:10 - Alternative vs. Complementary vs. Integrative Medicine 3:50 - Eastern vs. Western Medicine 5:00 - Principles of Integrative Medicine 7:20 - Osteopathic (DO) vs. Allopathic (MD) Medicine 9:35 - Naturopathy, Homeopathy & Functional Medicine 1...
An introduction to your host, what the podcast will be about (integrative medicine & psychedelics) and a primer on evidenced based medicine. 0:00 - Bio, Mary Ella Wood, DO Undergrad: Point Loma Nazarene University, San Diego, CA Medical School: Alabama College of Osteopathic Medicine, Dothan, AL Residency: General Surgery, Danbury Hospital, Danbury, CT Residency: Family Medicine, West Suburban Medical Center, Oak Park, IL 1:06 - Journey to Integrative Medicine 3:50 - What is Integrati...
In this episode we will take a deep dive into one of the leading causes of the global burden of disease-- hypertension, or high blood pressure. We will go over the pathophysiology, learn how hypertension develops and why it is so bad for the body. After understanding the root causes, we can then better understand how our traditional pharmaceuticals, lifestyle interventions, and holistic integrative therapies work to treat this disease. ... and SPOILER! Holistic approaches turn out to b...



