This Week in Pharmacy

This week on TWIRx, we head into NCPA 2026 with independent community pharmacy front and center — from artificial intelligence and consolidation to supply-chain economics and policy reform.   We start with the TWIRx Rumor Mill — Behind the Counter Intelligence, looking at three developing stories worth watching.   TWIRx RUMOR MILL — TOP 3   1. Another massive pharmacy transaction may be coming.   The owner of Walgreens Boots Alliance is reportedly nearing a deal to sell UK pharmacy giant Boots to the Weston family in a transaction valued at roughly $9 billion, including debt. The Weston interests already control Loblaw Companies and Shoppers Drug Mart in Canada. No final transaction has been announced, so this remains one to watch.   TWIRx Take: Pharmacy consolidation isn't slowing down. As major organizations continue reorganizing, buying, selling, and vertically integrating assets, what does that mean for independent pharmacy — and where does scale become too much scale?     2. Specialty pharmacy keeps getting bigger — and Cigna sees an enormous opportunity.   At its 2026 Investor Day, Cigna identified a specialty pharmacy and care-services market approaching $500 billion, with Accredo and its specialty operations positioned as major growth drivers.   TWIRx Take: Follow the money. Specialty drugs, rare disease, biologics, infusion and complex medication management continue to reshape pharmacy economics. The question for community pharmacy is: How much of this expanding market can independents capture?   3. AI is moving from pharmacy experiment to pharmacy infrastructure.   Just as NCPA prepares to make AI implementation one of the major topics at its 2026 Annual Convention, health-profession regulators are increasingly discussing governance and accountability surrounding AI. NCPA's programming includes real-world AI implementation and operational applications for community pharmacies.   TWIRx Take: The conversation is changing from "Should pharmacy use AI?" to "How do we use it responsibly, profitably and safely?"   And that takes us directly into our first featured conversation.   SEGMENT 1 John Boos, PharmD, MBA — HendrenAI AI Meets Independent Community Pharmacy   Sponsored by HendrenAI and Independent Pharmacy Cooperative   NCPA 2026 officially opens October 3 in Kansas City, with independent pharmacy owners and innovators gathering to focus on practical ways to increase efficiency, expand services and strengthen pharmacy profitability. AI implementation is specifically among this year's featured topics.   In Part One of our conversation with John Boos, PharmD, MBA of HendrenAI, we set the stage for NCPA 2026 and examine what artificial intelligence can realistically do for independent pharmacy.   This isn't AI replacing the pharmacist.   It's AI giving pharmacists and their teams additional capacity.   As margins tighten and workload continues to increase, the pharmacies that intelligently automate routine work may be able to redirect valuable human time toward the things pharmacists do best: patients, clinical care, relationships and growing the business.   SEGMENT 2 Yvonne Dominguez — Independent Pharmacy Cooperative IPC Acquires IntegralRx   Independent Pharmacy Cooperative recently announced its acquisition of IntegralRx, bringing together two organizations serving independent community pharmacies.   IntegralRx has supported thousands of pharmacies through purchasing opportunities, service and pharmacy relationships. IPC says the acquisition will expand access to products, services and resources designed to help pharmacy owners remain competitive and profitable.   We talk with Yvonne Dominguez about:   Why IPC made the acquisition What IntegralRx brings to the cooperative What changes — and what stays the same — for IntegralRx pharmacies How scale can strengthen independent pharmacy purchasing power Why independent pharmacies increasingly need collaboration without surrendering their independence   TWIRx Question: Can cooperatives create enough collective scale to give independent pharmacies some of the economic leverage enjoyed by vertically integrated competitors?   SEGMENT 3 David A. Hargraves — CEO, Pharma Logistics Jessica Daley — Industry Intelligence Pharmacy Supply Chain: Fighting for Every Dollar   Finally, we turn to an issue that doesn't always generate headlines but directly affects pharmacy profitability:   What happens to medication inventory after a pharmacy can no longer use it?   Pharmacies continue to face significant economic pressure, and many of the largest forces affecting reimbursement remain outside the direct control of the pharmacy owner.   But there are areas pharmacies — and policymakers — can change.   One is pharmaceutical return policy.   The Problem   Pharmacy economics are being squeezed from multiple directions.   Reimbursement pressure. Inventory expense. Expired medication. Operational costs. Supply-chain complexity.   When margins are razor thin, seemingly small inefficiencies become substantial.   The Opportunity   Medication return policies represent an area where pharmacies may have an opportunity to recover value that otherwise disappears from the business.   Virginia's regulations, for example, specifically address circumstances under which drugs can be returned within the supply chain while maintaining appropriate storage conditions, documentation and product integrity.   The Bigger Conversation   With David A. Hargraves, CEO of Pharma Logistics, and Jessica Daley of Industry Intelligence, we examine how smarter pharmaceutical returns and responsible policy reform could improve pharmacy economics.   Closing Thought   As we head into NCPA 2026, the independent pharmacy conversation isn't simply about surviving another difficult year.   It's about finding leverage.   Leverage through AI.   Leverage through cooperative scale.   Leverage through better supply-chain economics.   And leverage through policy change.   Independent pharmacy may not control every economic force affecting the profession — but this week's TWIRx demonstrates that there are still areas where pharmacy owners, innovators and advocates can take action.   We'll see you in Kansas City for NCPA 2026.

In this special episode of This Week in Pharmacy, Todd Eury welcomes Vox, the PPN and RxPR Intelligence Officer, for a timely conversation about the forces reshaping pharmacy. Together, they examine the reimbursement pressures threatening independent pharmacies, the progress—and unfinished work—of PBM reform, and how artificial intelligence can augment pharmacists, strengthen operations, and create more time for meaningful patient care. The discussion also looks ahead to NCPA 2026 in Kansas City, emerging innovations from Hendren AI and FDB, YARAL Pharma’s support of community pharmacy, and the upcoming Veterans Pharmacy Care Summit. The message is clear: pharmacists and pharmacy technicians must engage lawmakers, host pharmacy tours in 2027, and share the patient stories that demonstrate pharmacy’s value. This is not our platform. This is your platform.  

In this IPC-sponsored episode, Todd Eury explores how manufacturer-direct programs, direct-to-consumer channels, cash-pay models, specialty carve-outs, and new reimbursement structures are reshaping medication access and independent pharmacy.   Joining the conversation are Shelley Bailey of Independent Pharmacy Cooperative and Sammy Salem, Principal Owner and COO of Vios Health and an Executive Board Member of the AAPARx.   Manufacturer-direct care is often associated with websites, telehealth, and mail-order fulfillment—but it does not have to exclude community pharmacy. IPC is developing infrastructure that allows patients to receive manufacturer-supported pricing while participating independent pharmacies remain the dispensing location.   The discussion examines IPC’s manufacturer-sponsored GLP-1 opportunities and a broader network covering more than 140 branded medications. Shelley and Sammy explain how these programs can improve patient affordability, create more sustainable pharmacy economics, and help independent pharmacies reconnect with patients lost to online and manufacturer-controlled channels.   Topics include:   Whether the traditional pharmacy benefit is beginning to fragment How manufacturer-direct programs can include independent pharmacy The economics behind manufacturer-supported reimbursement Finding patients facing denied authorizations, high deductibles, lost coverage, or limited brand access Why excellent service must now be paired with digital access and new payment models Employer drug carve-outs and the importance of evaluating total benefit economics Point-of-sale affordability and acquisition-cost protections What manufacturers need to provide for pharmacy participation How successful pharmacies can prepare for the next access model   The central message is clear: the industry may not need to create new dollars—it needs to change where existing dollars land.   In partnership with GoodRx, this manufacturer-direct program combines GoodRx’s trusted consumer platform and broad patient reach with IPC’s nationwide network of independent pharmacies. Together, we create a more direct and accessible path from patient engagement to prescription fulfillment—while keeping community pharmacies at the center of care.   IPC GPO members interested in participating should contact their IPC Regional Director. Other IPC members, affiliates, and interested pharmacies can reach IPC Digital Health at [email protected].   Host: Todd S. Eury, Pharmacy Podcast Network Guests: Shelley Bailey, IPC; Sammy Salem, AAPARx and Vios Health Sponsored by: Independent Pharmacy Cooperative

This week on TWIRx, we’re looking at the expanding role of pharmacists in public health, value-based care, artificial intelligence, medication intelligence, and the technology infrastructure supporting independent community pharmacy.   We begin with a special conversation featuring Alex J. Adams, PharmD, MPH, Assistant Secretary for the Administration for Children and Families (ACF), and Pennsylvania pharmacy leader Robert “Rob” Maher, PharmD, President and Chief Operating Officer of the Pennsylvania Pharmacists Care Network (PPCN).   Dr. Adams brings a pharmacist’s perspective to federal health and human services leadership, while Maher leads a statewide clinically integrated pharmacy network focused on measurable patient outcomes. Together, we discuss how pharmacists are becoming increasingly involved in public health initiatives and how organizations such as PPCN are helping demonstrate the value of pharmacist-provided care through value-based models in Pennsylvania.   Next, we continue our countdown to NASP inSPire 2026 with one of PPN’s Podcast Press Sponsors, Hendren AI.   John Boos, PharmD, MBA, Founder and CEO of Hendren AI, joins us to examine the growing role of artificial intelligence in specialty pharmacy and rare disease management. We discuss how AI-enabled tools can support pharmacists by processing complex information, improving workflow efficiency, automating administrative processes, and helping pharmacy teams devote more time to clinical care and patient engagement.   Our 3rd segement on today’s TWIRx, we catch up with Vince Costanzo of RxBLU for an important discussion about the rapidly changing pharmacy technology landscape.   Pharmacy software today is about far more than features and functionality. For an independent pharmacy, its technology platform can sit at the center of dispensing, claims, inventory, patient communication, workflow, and business continuity.   We discuss why pharmacies should evaluate not only the technology they purchase, but also the stability, accessibility, support structure, and long-term strategy of the company behind it. As consolidation continues throughout healthcare technology, independent pharmacy owners need to understand what a potential acquisition, ownership change, or shift in corporate priorities could mean for the software platforms their operations depend upon.   Our featured Podcast Press Sponsor is First Databank — FDB.   David Delaney, MD, President of FDB, joins TWIRx to discuss the company's newly announced FDB Script Agent™, an AI-powered prescribing agent designed to move ambient listening beyond clinical documentation.   FDB Script Agent converts patient-clinician dialogue into structured prescriptions ready for clinician review, using FDB medication intelligence to provide clinical grounding and codification rather than relying on simple natural-language processing alone. We explore what this next generation of ambient AI could mean for prescribing workflows, medication safety, clinicians, and ultimately the pharmacies receiving those prescriptions.   It’s another packed edition of This Week in Pharmacy — connecting pharmacy leadership, public health, specialty pharmacy, artificial intelligence and the technology shaping the future of the profession.   This is TWIRx — This Week in Pharmacy, from the Pharmacy Podcast Network.

Specialty Pharmacy Access, Innovation & Independent Pharmacy Growth   This Week in Pharmacy, we explore specialty pharmacy, pharmacy innovation, emerging career opportunities, and new business models for independent community pharmacy.   Today’s episode is sponsored by Clearway Health, Value Drug Company, and FDB (First Databank, Inc.)   First, Allison Arant of Clearway Health joins us to discuss the next phase of specialty pharmacy within hospitals and health systems.   As rare disease and specialty therapies become more complex, health systems are looking for better ways to improve medication access, strengthen continuity of care, and keep patients connected to trusted clinical teams.   Todd and Allison discuss how health-system specialty pharmacy can expand community access and improve management of complex and rare disease treatments.   Learn more: https://www.clearwayhealth.com/   National Association of Specialty Pharmacy (NASP) #inSPire2026   Next, we preview inSPire 2026, taking place September 22–25, 2026, at the Gaylord National Resort & Convention Center in National Harbor, Maryland.   The specialty pharmacy community will come together to discuss medication access, emerging therapies, technology, patient services, clinical care, and the continued evolution of specialty pharmacy.   The Next Dose Summit   Then we welcome Jordan Smith, PharmD, AAHIVP, CPGx, and Melinda Fowler, RPh, ABAAHP, FAAFM to preview The Next Dose Summit, happening October 14–15, 2026.   RxPR and the Pharmacy Podcast Network are proud press and media partners.   The event focuses on innovation, entrepreneurship, leadership, emerging career pathways, and new opportunities for pharmacists looking beyond traditional roles.   It is designed for pharmacists, students, entrepreneurs, and healthcare leaders asking one important question:   What’s next for pharmacy — and what’s next for me?   Register here: https://www.jscommunitycare.org/store/p/2026-the-next-dose-summit-registration   Expanding Independent Pharmacy   Finally, Rick Seipp, PharmD, President and CEO of Value Drug Company, returns to discuss creative strategies for expanding independent community pharmacy.   Todd and Rick explore cash-based pharmacy, transparent pricing, clinical services, new revenue streams, and other non-PBM-dependent models that can help independent pharmacies diversify and grow.   The conversation focuses on how community pharmacies can strengthen their businesses while continuing to serve as trusted healthcare destinations.   Learn more: https://www.valuedrugco.com/   Sponsored By   Clearway Health https://www.clearwayhealth.com/   Value Drug Company https://www.valuedrugco.com/   First Databank — FDB https://www.fdbhealth.com/   TWIRx — This Week in Pharmacy is hosted by Todd S. Eury and produced by the Pharmacy Podcast Network — Amplifying the Voice of Pharmacists & Our Profession.