This Week in Startups

Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

Waymo Madness in SF! Why robotaxis clogged the streets | E2227

This Week In Startups is made possible by:Caldera + Lab - http://calderalab.com/TWISTCrusoe Cloud - https://crusoe.ai/buildUber - http://uber.com/twistToday’s show: Why did a power outage in the Bay Area cause Waymos to pile up on city streets?Jason was actually in San Francisco to take in the spectacle of Waymos blocking traffic. But why did this happen? And can we look forward to a day when automated cars are more graceful and coordinated than ballet dancers performing “Swan Lake”? We’re asking the tough (and also culturally erudite) questions!PLUS self-driving cars are coming to London, Coinbase’s buying spree continues, another entrant in our nearly-complete Gamma Pitch Deck Competition, AND why Jason predicts that Google is going to buy UBER!You won’t want to miss this holiday TWiST!Timestamps:(00:00) It’s a holiday TWiST! Jason’s calling in from vacay in Lake Tahoe.(03:11) Jason was in SF for the great Waymo power outage!(06:06) Why Jason says one day Waymos will be better coordinated than dancers in “Swan Lake”(07:33) We predicted Starlink coming to every Tesla nearly 3 years ago!(09:05) Caldera + Lab: Whether you’re starting fresh or upgrading your routine, Caldera Lab makes skincare simple and effective. Head to http://calderalab.com/TWIST and use TWIST at checkout for 20% off your first order.(11:29) Jason calls what Tesla’s Optimus team is planning “otherworldly”(14:39) Why Jason thinks we’re all going to live in an “Opt-In Truman Show” someday soon(18:52) Baidu, Lyft, and Uber bring self-driving cars to London… they don’t have them already?!(20:49) Crusoe Cloud: Crusoe is the AI factory company. Reliable infrastructure and expert support. Visit https://crusoe.ai/build to reserve your capacity for the latest GPUs today.(24:02) When do we get to 50% of all rides being done by autonomous vehicles… and how many robotaxis will that take?(27:50) Why Jason thinks Google is going to buy… UBER?!(31:12) Uber AI Solutions: Your trusted partner to get AI to work in the real world. Book a demo with them TODAY at http://uber.com/twist(32:30) Will it eventually come down to which car can drive a mile for the cheapest?(35:08) Coinbase picks up The Clearing Company, which makes frameworks for prediction markets(39:50) How much did the biggest AI models improve this year?(44:09) Who’s going to actually buy Warner Bros? We’re checking the Polymarket.(47:06) GAMMA PITCH w/ Jonathan Sherman of Lumix Ads(51:00) Why Jason says Jonathan’s pitch is a 9.5 out of 10(52:50) What Jason looks for in a founder: “a big audacious vision”(54:18) How Lumix (safely) collects users’ “mobile ad ID” on the go to identify themSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com/Check out the TWIST500: https://twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcp*Follow Lon:X: https://x.com/lons*Follow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelm/*Follow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanis/*Thank you to our partners:(09:05) Caldera + Lab: Whether you’re starting fresh or upgrading your routine, Caldera Lab makes skincare simple and effective. Head to http://calderalab.com/TWIST and use TWIST at checkout for 20% off your first order.(20:49) Crusoe Cloud: Crusoe is the AI factory company. Reliable infrastructure and expert support. Visit https://crusoe.ai/build to reserve your capacity for the latest GPUs today.(31:12) Uber AI Solutions: Your trusted partner to get AI to work in the real world. Book a demo with them TODAY at http://uber.com/twist

12-23
59:35

Level up your copywriting w/ Sam Parr | E2226

This Week In Startups is made possible by:Luma AI - https://lumalabs.ai/twistNorthwest Registered Agent - https://www.northwestregisteredagent.com/twist Lemon IO - https://lemon.io/twistToday’s show: DID YOU KNOW… most of the tried and true techniques devised by marketing gurus in the ‘40s and ‘50s still apply today?On TWiST, we’re joined by online marketing expert Sam Parr, host of “My First Million” and founder of Hampton. He’s sharing all of his top tips and tricks for making your writing more compelling, and converting your readers into new customers.In this essential pod for any and all founders, hear Jason and Sam run down their list of the best-ever marketing books, why there’s no such this as “too long” only “too uninteresting,” when to use AI and when to rely on your own brain, why you’re the average of your five best friends, and lots more deep insights.Timestamps:(00:00) Sam Parr of The Hustle, Hampton, and My First Million is here to teach us how to become better copywriters(03:59) How Sam got interested in the (then-shady) world of internet marketing(06:26) Why Sam recommended THESE advertising books to Jason(08:15) All the principles that ad execs developed in the ‘50s still work!(09:43) Glengarry had it right; the magic of A.I.D.A.(11:19) Luma AI - Stop guessing and start directing with Ray3 Modify from Luma AI, the AI-powered post production tool. Explore it at: https://lumalabs.ai/twist(14:30) There’s no such thing as “too long,” just “too uninteresting”(16:15) The goal is to write at a 4th grade reading level(18:12) Why Sam only uses AI for “The Big Idea,” not the actual writing(19:37) Why you’re the average of your five best friends(21:14) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(22:15) Using AI to dig in and research, to make your writing more interesting(23:42) CopyWork: The technique that helped Sam fine tune his writing(28:41) Avoiding “The Feature Death March”(30:56) Lemon.io - Get 15% off your first 4 weeks of developer time at https://lemon.io/twist(32:00) Words are better than images, but videos are better than anything(34:43) Why stories make such a huge impact(37:36) Sam and Jason are both obsessed with the book “How to Be Rich”(43:02) First World Problems are still problems!!(44:31) Why Sam launched Hampton and what it takes to get in(47:10) Why scaling a community is so much harder than launching(51:04) The lessons founders can take from Ted Turner(58:36) What Jason likes best about My First Million(1:00:28) It’s never too early to get your first $10 million(1:04:07) How accurately did Producer Claude guess what Sam was going to teach us?*Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com/Check out the TWIST500: https://twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcp*Follow Lon:X: https://x.com/lons*Follow Alex:X: https://x.com/alexLinkedIn: [https://www.linkedin.com/in/alexwilhelm/*Follow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanis/*Thank you to our partners:(11:19) Luma AI - Stop guessing and start directing with Ray3 Modify from Luma AI, the AI-powered post production tool. Explore it at: https://lumalabs.ai/twist(21:14) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(30:56) Lemon.io - Get 15% off your first 4 weeks of developer time at https://lemon.io/twist

12-20
01:06:13

INSIDE How AI Startups hire, AI Roundtable with Wade Foster, Mikey Schulman, and Ali Ansari | E2225

This Week In Startups is made possible by:LinkedIn Ads- http://linkedin.com/thisweekinstartupsSquarespace - https://squarespace.com/twistEnterpret - http://Enterpret.com/twistToday’s show: How do top tech CEOs hire? AI has thrown out the playbook for getting hired — so what are the most innovative firms looking for? Anyone can learn any skill and automate much of it, what is to be valued in the modern labor market?On our first AI Roundtable episode of TWiST, Jason is joined by three top tech CEOs: Wade Foster (Zapier), Mikey Schulman (Suno), and Ali Ansari (Micro1). They each give their perspective on the tech talent wars and how to get hired in 2026.The resounding answer on how to get a job? JUST START DOING THE JOB! If you want to be a designer, start sending designs to companies you want to be hired by — don’t just sit around waiting to be hired. The biggest value you can bring is a “high agency” mindset to your company and the role. Show you get after it!They are also hitting on:- How AI is getting used to make music today- The tech industry’s communication problem- How to raise kids in the age of AITimestamps:(00:00) It’s our first ever “This Week in AI” Roundtable, and we’ve got an amazing panel(05:50) How Meta and OpenAI skew how everyone thinks about compensation(09:37) The importance of looking beyond SF for talent(10:24) LinkedIn Ads: Start converting your B2B audience into high quality leads today. Launch your first campaign and get $250 FREE when you spend at least $250. Go to http://linkedin.com/thisweekinstartups to claim your credit.(14:39) Is AI making more people seek out developer jobs?(18:36) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://squarespace.com/twist(19:36) When design becomes its own bottleneck… and some workarounds.(22:37) It’s not how much you know, it’s how adaptable you are(24:10) The best way to get hired: just start doing the job(30:09) Why Ali says we’re entering the "Post-Training"(31:34) Enterpret - Enterpret turns feedback noise into Customer Intelligence, so your team knows exactly what to fix and build next. Head to http://Enterpret.com/twist to book a demo and see it in action.(33:32) Understanding the value of your company’s data and using it to get better outputs(41:14) Mikey calls Suno the “GLP-1s of the music industry”: everyone uses it but no one admits it(46:39) Mikey Talks break out AI artists like Xania Monet(49:32) Questions raised about how AI will effect job markets(54:43) How AI and robotics will unlock new jobs and opportunities(58:48) Possible solutions to the AI and automation question.(01:04:03) Technology's communication problem and how to fix it.(01:05:24) Are people replacing their friends with AI?(01:08:11) How CEOs are thinking about raising young kids in the world of AI.(01:12:21) Lightning round on AI agents, workflows vs. agents(01:16:49) Trapped value in sales calls, questions, company meetings that are unlocked by AI(01:22:10) How Ali pitched the LAUNCH team outside of a Jeni's Ice Cream storeSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com/Check out the TWIST500: https://twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Jason:X: https://twitter.com/JasonThank you to our partners:(10:24) LinkedIn Ads: Start converting your B2B audience into high quality leads today. Launch your first campaign and get $250 FREE when you spend at least $250. Go to http://linkedin.com/thisweekinstartups to claim your credit.(18:36) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://squarespace.com/twist(31:34) Enterpret - Enterpret turns feedback noise into Customer Intelligence, so your team knows exactly what to fix and build next. Head to http://Enterpret.com/twist to book a demo and see it in action.

12-18
01:26:45

Is this the end for the Roomba? Why iRobot went bankrupt | E2224

This Week In Startups is made possible by:Vanta - https://www.vanta.com/twistNetSuite - https://www.netsuite.com/twistLemon.io - https://lemon.io/twist*Today’s show: Domestic robots have never been hotter… so why is iRobot in so much trouble?!On TWiST, we’re investigating the recent troubles facing the automated vacuum robot, Roomba. We’ve all seen these little discs sweeping up our friends’ floors… but now the company behind them is running out of cash.What happened to iRobot, and would things have turned out differently if they had been sold to Amazon back in 2022?PLUS why Jason thinks you should spend your disposable income on investing… Is Alex still a journalist, and what does that actually mean for his portfolio?… Are founders and investors too cautious when it comes to signaling risk?… Why did all those internal Pipe documents leak online?… And MUCH MORE!Timestamps:(00:00) Why Jason loves Incentivizing New Ventures and Economic Strength Through Capital Formation!(09:48) Jason warns “no one is coming to help you with your job loss”; you’re on your own!(10:21) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(13:05) Why Jason thinks laid-off HR folks should be starting their own “micro-funds"(14:13) Does Alex consider himself a journalist? Is it unethical for him to invest in companies? (Let’s get INTO IT.)(16:02) You can’t become complacent when you’re in the lead!(20:03) Why you should use disposable “entertainment” income on investing(22:32) Netsuite - Get the free business guide Demystifying AI at https://www.netsuite.com/twist(23:36) $9B in new funds?! What is Lightspeed up to?(26:10) Is everyone too cautious about “signaling risk”?(28:39) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(31:21) How does Jason think those Pipe documents leaked? And WHY?(38:15) The critical importance of diversification(39:35) iRobot went BANKRUPT! Who killed the Roomba?(44:47) Are there ANY potential deals that would bother Jason? It’s all about market share.(48:18) HuggingFace is moving major Reachy Minis! How open source turns everything upside down.(53:22) How Polymarket will decide when/if the AI bubble “bursts.”*Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com/Check out the TWIST500: https://twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcp*Follow Lon:X: https://x.com/lons*Follow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelm/*Follow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanis/*Thank you to our partners:(10:21) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(22:32)  Netsuite - Get the free business guide Demystifying AI at https://www.netsuite.com/twist(28:39) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twistGreat TWIST interviews: Will Guidarahttps://youtu.be/pvJa2pzuXWQEoghan McCabehttps://youtu.be/9dHN4YFkgv4Steve Huffmanhttps://podcasts.apple.com/us/podcast/reddit-ceo-steve-huffman-on-mod-revolt-building-a/id315114957?i=1000617333424Brian Cheskyhttps://podcasts.apple.com/ca/podcast/airbnb-ceo-brian-chesky-on-early-rejection-customer/id315114957?i=1000611761112Bob Moestahttps://youtu.be/y2UMzSqX94QAaron Leviehttps://podcasts.apple.com/ca/podcast/box-ceo-aaron-levie-breaks-down-box-ai-and-generative/id315114957?i=1000612384545Sophia Amorusohttps://podcasts.apple.com/ca/podcast/sophia-amoruso-on-branding-raising-a-fund-portfolio/id315114957?i=1000601352978Reid Hoffmanhttps://podcasts.apple.com/ca/podcast/reid-hoffman-on-ais-crescendo-moment-regulation-and/id315114957?i=1000612548498Frank Slootmanhttps://podcasts.apple.com/ca/podcast/snowflake-ceo-frank-slootman-on-moving-the-needle-win/id315114957?i=1000602560622

12-16
01:00:42

Disney and OpenAI sign landmark deal… and we saw it coming! | E2223

This Week In Startups is made possible by:LinkedIn Ads - http://linkedin.com/thisweekinstartupsDevStats - https://www.devstats.com/twistCrusoe - https://crusoe.ai/buildToday’s show: FINALLY, you can hang out with Kylo Ren and Olaf the Snowman… thanks to the magic of AI.On TWiST, we’re digging into the mega OpenAI-Disney deal. Mickey is giving Sam Altman a $1 billion investment AND will allow is copyrighted characters to appear in Sora and ChatGPT images.Of course, Jason predicted this would happen WAY BACK during the summer months and even showed off his “Darth Calacanis” creation on the “All-In Podcast.”PLUS Amazon has been launching and pulling AI features from Prime Video… what gives? Jason’s predictions on the coming AI blowback and who’s on what side. Why he’s so focused on Education, Health Care, and Housing as issues. AND why founders should always take calls from Big Companies, even if it might just be a fishing expedition.It’s a new Friday TWiST! Check it out!Timestamps:(00:00) Lon joins Alex and Jason to talk about the big Disney-OpenAI deal bringing Disney characters to Sora(03:10) Jason totally called the Disney-OpenAI stuff on All-In(9:42) LinkedIn Ads: Start converting your B2B audience into high quality leads today. Launch your first campaign and get $250 FREE when you spend at least $250. Go to http://linkedin.com/thisweekinstartups to claim your credit.(18:59) DevStats - DevStats integrates your dev work and your business goals into a shared language that everyone can understand. Get 20% off, plus access to their dedicated Slack channel. Just go to https://www.devstats.com/twist.(20:15) Why Amazon Prime Video pulled its AI recaps and anime dubs(24:44) Who gets to set the rules around AI: The Debate Continues(26:13) Jason’s predictions on the AI blowback coming in 2026… with clips!(30:11) Crusoe Cloud: Crusoe is the AI factory company. Reliable infrastructure and expert support. Visit https://crusoe.ai/build to reserve your capacity for the latest GPUs today.(31:21) Is AI here to help people or replace them?(35:55) It’s all about EHH: Education, Health Care, Housing(40:47) How all of this and MORE will be impacted directly by AI automation(45:35) Why Alex wants to lower the temperature around AI Doomerism(51:19) JUST FOR FOUNDERS: When should you take a call from a BigCo?(53:45) Why Jason thinks just about everyone in media will lose to TikTok and YouTubeSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com/Check out the TWIST500: https://twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcp*Follow Lon:X: https://x.com/lons*Follow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelm/*Follow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanis/*Thank you to our partners:(9:42) LinkedIn Ads: Start converting your B2B audience into high quality leads today. Launch your first campaign and get $250 FREE when you spend at least $250. Go to http://linkedin.com/thisweekinstartups to claim your credit.(18:59) DevStats - DevStats integrates your dev work and your business goals into a shared language that everyone can understand. Get 20% off, plus access to their dedicated Slack channel. Just go to https://www.devstats.com/twist.(30:11) Crusoe Cloud: Crusoe is the AI factory company. Reliable infrastructure and expert support. Visit https://crusoe.ai/build to reserve your capacity for the latest GPUs today.

12-13
57:58

“The best founders find a way to make it happen”: VC Roundtable with Bryan Kim and David Clark | E2222

This Week In Startups is made possible by:Uber -  http://uber.com/twistPilot - https://pilot.com/twistNorthwest Registered Agent - https://www.northwestregisteredagent.com/twistToday’s show: Boom is still making supersonic jets but ALSO plans to start selling their turbines as power sources for AI data centers. It’s a perfect example of problem-solving on the go and how “the best founders… MAKE IT HAPPEN.”Join us for another insightful VC roundtable episode, featuring special guests Bryan Kim (a16z) and David Clark (Ven Cap).They’re discussing why Boom’s turbine announcement is about necessity AND opportunity PLUS…- Why we might NOT be in an AI bubble after all- Promoting your startup without spending your entire runway on marketing- Why founders need to be RELENTLESS- Bill Gurley’s classic response about Uber’s Total Addressable Market- AND LOTS MOREBill Gurley’s iconic “Miss By a Mile” post: https://abovethecrowd.com/2014/07/11/how-to-miss-by-a-mile-an-alternative-look-at-ubers-potential-market-size/Link to David’s LinkedIn (including the AI Bubble chart): https://www.linkedin.com/feed/update/urn:li:activity:7404139606398443520/Timestamps:(02:11) It’s a VC Roundtable with special guests Bryan Kim (a16z) and David Clark (Ven Cap)(03:07) Why Bryan is leading a Series A into learning app Oboe(06:20) Calculating a startup’s value to make everyone “somewhat unhappy”(09:19) How Oboe hits a lot of the same metrics that LAUNCH looks for in startups(11:58) Uber AI Solutions - Your trusted partner to get AI to work in the real world. Book a demo with them TODAY at http://uber.com/ai-solutions(12:57) How funds decide when to cash out and lock in some DPI(18:12) When some LPs want to sell and others want to buy…(19:57) Pilot - Visit https://www.pilot.com/twist and get $1,200 off your first year. (24:07) Is the threat of AI job displacement boosting self-improvement apps?(27:37) Why Jason says we’re all standing on the shoulders of Bill Gurley(29:46) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(31:28) Boom’s turbine pivot, and why it’s about necessity AND opportunity (in that order)(34:14) THE BEST FOUNDERS find a way to make it happen!(39:10) So… are we in an AI bubble? David says NOT NECESSARILY! Checking out the actual metrics.(44:36) We’re still SO EARLY in AI… We’re still seeing mostly skeuomorphic uses! (It’s a real word!)(48:06) William Gibson was right: “The Street finds its own uses for things”(51:11) How AI startups should think about margins(55:58) Why LAUNCH tells founders to “start at the high end”(57:33) Should founders spend a lot of $$$ on marketing in 2025? The panel disagrees!(1:00:05) Momentum vs. Product Release Velocity(1:03:26) It all comes back to the “relentlessness of the founder”(1:05:17) Our panel’s hopes and dreams for the coming year*Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcp*Follow Lon:X: https://x.com/lons*Follow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelm/*Follow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanis/*Thank you to our partners:(11:58) Uber AI Solutions - Your trusted partner to get AI to work in the real world. Book a demo with them TODAY at http://uber.com/ai-solutions(19:57) Pilot - Visit https://www.pilot.com/twist and get $1,200 off your first year. (29:46) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!

12-11
01:10:25

FLASHBACK: The future of remote work, juggling APIs, and dream integrations with Wade Foster of Zapier | E2221

This Week In Startups is made possible by:Goldbelly - Goldbelly.comEvery.io - http://every.io/Zite - zite.com/twistToday’s show:Today, Zapier’s a multi-billion company helping enterprises integrate AI agents and other time-saving shortcuts into their workflows… but we had the founder on TWiST when they were just getting started!In a 2016 chat, founder Wade Foster walked JCal through their 2012 seed round, running a small entirely remote team with no HQ, the complexities of building a tool that relies on third-party APIs, and why Microsoft Office was the “Holy Grail” for his integration software.PLUS we’ve got a new entrant in your Gamma Pitch Deck competition! Tour CEO/CTO Amulya Parmer tells us how his app is saving property managers time and grief, while eliminating “looky-loos” and increasing their “hit rate.”FINALLY, Alex chats with Tomas Puig of TWiST 500 marketing analysis startup Alembic. It turns out, LLMs aren’t ideal for scrutinizing marketing campaigns because they lack the requisite historical data. Find out how they’re using Spiking Neural Networks (SNN) to dig deeper than GPT and Claude can go.Timestamps:(02:40) Amulya from Tour opens the show with praise for Jason(03:34) Tour’s 2-minute Gamma pitch: automated property tours for managers(06:47) Why Jason thinks Tour is an ideal tool for Gen Z(10:01) Goldbelly - Goldbelly ****ships America’s most delicious, iconic foods nationwide! Get 20% off your first order by going to Goldbelly.com and using the promo code TWiST at checkout.(13:32) How Tour can eliminate “looky-loos” and increase the “hit rate”(14:38) Why Tour prices based on individual properties and apartments(19:13) Every.io - For all of your incorporation, banking, payroll, benefits, accounting, taxes or other back-office administration needs, visit every.io.(20:23) Jason wants to sprinkle some AI into Tour(24:29) Welcoming Tomas Puig from Alembic(25:12) Does epic-scale brand marketing actually pay off for these brands?(27:27) The hardest thing about being a marketer…(28:31) Alembic’s origins: organizing huge unstructured data sets(30:18) Zite - Zite is the fastest way to build business software with AI. Go to zite.com/twist to get started.(31:27) Case Study: making sense of Delta’s Olympics data(33:37) Applying simulation models and supercomputers to marketing data(35:48) How Spiking Neural Networks (SNN) help Alembic spot trends and link causal relationships(41:13) The key advantage of training models on private data(43:16) Building their own clusters vs. renting(44:41) “You don’t ask if you have Product Market Fit… You hold on for dear life.”(46:28) Flashback with Alex and Lon to Jason’s 2016 chat with Wade Foster of Zapier(54:48) The dangers of building atop other platform’s APIs(01:03:00) What Zapier learned pre-pandemic about leading remote teams(01:13:12) Why MS Office was the “Holy Grail” for early ZapierSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:01) Goldbelly - Goldbelly ****ships America’s most delicious, iconic foods nationwide! Get 20% off your first order by going to Goldbelly.com and using the promo code TWiST at checkout.(19:13) Every.io - For all of your incorporation, banking, payroll, benefits, accounting, taxes or other back-office administration needs, visit every.io.(30:18) Zite - Zite is the fastest way to build business software with AI. Go to zite.com/twist to get started.Follow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartups

12-10
01:17:19

What’s REALLY going on with those “ads” in ChatGPT | E2220

This Week In Startups is made possible by:Superhuman - https://superhuman.com/podcastSquarespace - https://squarespace.com/twistEnterpret - https://www.enterpret.com/dlp/this-week-in-startupsToday’s show: A screenshot showing a “Target Ad” in ChatGPT results went viral… over the weekend, but the OpenAI chatbot has NOT actually opened the advertising floodgates just yet.As ChatGPT staffers were quick to explain on social media, this was actually an invitation for a user to integrate their Target account into ChatGPT, for an easier agentic browsing and shopping experience.But it does prompt Jason and Alex to ask some intriguing questions… Is OpenAI just waiting for Google or someone else to launch AI ads first, and face the inevitable flood of backlash they’ll presumably receive? Is there someone at OpenAI already thinking DEEPLY about how these in-feed ads should work? And what does this mean for their wager on when ChatGPT is going to actually get ads? Is that already decided?These answers and more are coming your way on today’s action-packed TWiST… PLUS the latest on the Warner Bros Discovery-Netflix deal, PR guru Lulu Cheng Meservey’s new venture fund, and why Jason and Lon are obsessing about Apple TV’s “Pluribius.”Timestamps:(01:59) They put Target ads in ChatGPT? Or was it just an integration? Is there a difference?(5:24) Is someone at OpenAI really thinking deeply about how in-feed ads should work?(07:36) Is OpenAI just waiting for Google to start running ads to post their own? Jason has suspicions…(10:01) Why Jason thinks startup people have so much trouble communicating with normies(10:32) Superhuman - Get AI that works where you work. Unlock your Superhuman potential at http://superhuman.com/podcast(13:22) The insane competition now facing down OpenAI and Sam Altman(18:40) Why Jason will no longer use data from SaaS companies looking for a marketing win(19:52) Does this mean ChatGPT TECHNICALLY has ads? Does Alex win the bet?! What does Polymarket think?(20:36) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://squarespace.com/twist(25:17) Why Jason is already tired of the Netflix-Paramount-WBD story(30:06) Enterpret - Enterpret turns feedback noise into Customer Intelligence, so your team knows exactly what to fix and build next. Head to http://Enterpret.com/twist to book a demo and see it in action.(34:03) President Jason’s new proposal: A 60-day “pre-approval” antitrust window(47:29) Why Jason’s not interested in news commentary… just the facts.(51:40) Jason and Lon take a few moments to praise “Pluribus”(54:45) PR guru Lulu Cheng Meservey is starting a venture firm… here’s why she wants to start a “movement”(58:05) Why PR people hate but also respect JasonSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com/Check out the TWIST500: https://twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcp*Follow Lon:X: https://x.com/lons*Follow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelm/*Follow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanis/*Thank you to our partners:(10:32) Superhuman - Get AI that works where you work. Unlock your Superhuman potential at http://superhuman.com/podcast(20:36) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://squarespace.com/twist(30:06) Enterpret - Enterpret turns feedback noise into Customer Intelligence, so your team knows exactly what to fix and build next. Head to http://Enterpret.com/twist to book a demo and see it in action.

12-09
01:02:24

Netflix buys WB + why Jason should run Disney | E2219

This Week In Startups is made possible by:Sentry - http://sentry.io/twistLinkedIn Ads - http://linkedin.com/thisweekinstartupsPipedrive - pipedrive.com/twistToday’s show:Netflix wants to gobble up Warner Bros. Do they just want to own Batman and Harry Potter, or is this secretly about destroying movie theaters?Sure, this is usually a startup show, but news THIS BIG warrants attention! So Lon stops by to tell Jason and Alex about the big Netflix acquisition news, why so many theatrical movie fans are terrified for the future, and why this might face particular regulatory scrutiny both at home and abroad.PLUS… are Googlers gaming Polymarket? This is one scenario in which prediction markets are NOT exactly like stocks.THEN we’re looking at some of our favorite startups from the Fall ‘25 Y Combinator cohort (and asking Producer Claude for his picks)… Considering why Perplexity keeps getting sued and how they can stop it… and doing a victory lap for Jason’s early investment in breakout AI training project Micro1.Timestamps:(02:05) Netflix buying Warner Bros! Jason, Lon and Alex react.(05:04) Jaytrade Update: J kind of missed the boat on this one(05:36) What does this mean for theatrical cinema?(08:42) Sentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWIST(09:52) Jason’s pitch to Disney CEO Bob Iger (please send this to him!)(19:36) LinkedIn Ads: Start converting your B2B audience into high quality leads today. Launch your first campaign and get $250 FREE when you spend at least $250. Go to http://linkedin.com/thisweekinstartups to claim your credit.(23:29) Is this deal going to get approval, at home and abroad?(25:52) Are Googlers gaming Polymarket?(28:02) Can you do “insider trading” on a prediction market?(29:23) Pipedrive - Bring your entire sales process into one elegant space. Get started with a 30 day free trial at pipedrive.com/twist(37:00) How accelerators like Y Combinator serve as “finishing schools” for startups(37:52) A Quick Look at some of our fav companies from YC’s Fall ’25 cohort(39:01) Why startups need to “skate to where the puck is going”(40:08) Why sometimes old ideas (like solar-powered aircraft) are often worth revisiting(45:29) Jason’s advice for founders (and investors) in the “feel good” or activist space(50:48) Why Lon, Alex, and Claude ALL thought Hyperspell sounds like a hot startup(52:58) Perplexity getting sued again! Why can’t they make friends!(57:51) Meanwhile, Meta’s signing AI deals with news publications.(59:21) Micro1, which Jason helped to fund, has hit $100M ARR! Why do AI companies need so many experts?Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(8:42) Sentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWIST(19:36) LinkedIn Ads: Start converting your B2B audience into high quality leads today. Launch your first campaign and get $250 FREE when you spend at least $250. Go to http://linkedin.com/thisweekinstartups to claim your credit.(29:23) Pipedrive - Bring your entire sales process into one elegant space. Get started with a 30 day free trial at pipedrive.com/twist

12-06
01:02:29

Getting past the “Cardinal Sins of Delegating” with Jonathan Swanson of Athena | E2218

This Week In Startups is made possible by:Northwest Registered Agent - https://www.northwestregisteredagent.com/twistCrusoe - http://crusoe.ai/buildGusto - https://www.gusto.com/twistToday’s show: Delegating is its own unique skill, requiring training and a real investment of time and attention.On TWiST, Jason chats for a full hour with the founder of one of his favorite startups, Athena, which trains online assistants and pairs them with busy founders and executives. (Jason has 2!) But getting the MOST out of your executive assistants is less obvious than it looks. Jonathan unpacks some of the secrets to “Black Diamond Delegating,” and how he manages to keep 6 different high-level helpers operating at once.Plus, Jason and Jonathan look back at the Open Angel Forum days, where Jason invested in Jonathan’s previous company, Thumbtack, praise the “Checklist Manifesto,” discuss the telltale signs you’ve achieved market pull, and lots more insights.Timestamps:(01:53) We’re joined by Jonathan Swanson from one of JCal’s fav startups, Athena!(02:02) Jason and Jonathan first met during the Open Angel Forum, when Jonathan was working on Thumbtack(06:44) Finding the “little touches” that can help make an app more delightful(9:47) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(12:05) The shift from Thumbtack to Athena was all about time(12:52) How Jonathan delegates to 6 exec assistants at once(14:22) Pricing Athena’s EAs: Jason runs the numbers(15:09) Why Athena made Jason believe in hiring assistants again(18:15) Getting past the “Cardinal Sins of Delegation”(19:38) Crusoe Cloud: Crusoe is the AI factory company. Reliable infrastructure and expert support. Visit https://crusoe.ai/build to reserve your capacity for the latest GPUs today.(20:48) Will AI ever be able to replace Athena assistants?(23:41) Inside how Athena finds and trains assistants from around the world(27:01) How JCal became an Athena Ambassador… and almost crashed the system!(30:55) Gusto - Check out the online payroll and benefits experts with software built specifically for small business and startups. Try Gusto today and get three months FREE at https://www.gusto.com/twist(32:11) The magic of having assistants work on “backstop projects” and creative tasks(37:14) How to know when you have achieved market pull(40:05) Why getting the most out of delegating takes real investment and training(44:36) More praise for the Checklist Manifesto(46:26) Jonathan gives us a peek at what “Black Diamond Delegation” looks like(52:14) Jason’s early experiences hiring overseas assistants, from the Mahalo days*Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcp*Follow Lon:X: https://x.com/lons*Follow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelm/*Follow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanis/*Thank you to our partners:(9:47) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(19:38) Crusoe Cloud: Crusoe is the AI factory company. Reliable infrastructure and expert support. Visit https://crusoe.ai/build to reserve your capacity for the latest GPUs today.(30:55) Gusto - Check out the online payroll and benefits experts with software built specifically for small business and startups. Try Gusto today and get three months FREE at https://www.gusto.com/twist

12-04
57:11

Monumental Makes Construction Bots Play Nice Together | E2217

This Week In Startups is made possible by:LinkedIn Ads - http://linkedin.com/thisweekinstartupsVanta - https://www.vanta.com/twistPilot - https://pilot.com/twistToday’s show: Did you know there’s actually a shortage of US bricklayers? It’s TRUE! So feel free to marvel at Monumental’s brick-laying robots. They’re not putting anyone out of work, but filling a much-needed gap.Join Alex and Monumental founder/CEO Salar al Khafaji for a deep-dive on how the startup is making construction robots play nice together by maintaining separate “zones” of operation, why Salar thinks startups need to focus on truly complex, real-world problems to truly blossom, and the secrets of fundraising in Europe.PLUS Alex chats with Seasats CEO Mike Flanigan about designing the next generation of autonomous marine crafts. (That is to say, ocean drones.) From their home base in San Diego, the company is trying to get completely independent of all Chinese parts. Find out how it’s going, how they’re overcoming the “wildly negative” ROI on maritime tech, and why we have so few defenses against tiny, agile drones.All that AND Jason takes some of YOUR Founder Questions.Timestamps:(03:23) How Monumental determined what kinds of robots construction sites need the most(06:49) How maintaining “zones” ensure that the robots all play nice with one another(07:52) There’s a shortage of bricklayers, so Monumental’s NOT taking anyone’s job(9:16) LinkedIn Ads: Start converting your B2B audience into high quality leads today. Launch your first campaign and get $250 FREE when you spend at least $250. Go to http://linkedin.com/thisweekinstartups to claim your credit.(13:21) Why startups need to tackle large-scale, complex, real-world problems to really grow(15:44) Why Monumental is building in The Netherlands, and running pilots in the UK(19:07) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(20:44) Why construction is unique among applications for automation and robots(26:01) Salar argues that fundraising in Europe is not as hard as you may have heard(27:55) We don’t just need housing, we need BEAUTIFUL housing(31:11) Pilot - Visit https://www.pilot.com/twist and get $1,200 off your first year. (33:25) How the Scout autonomous boat challenge inspired Seasats(35:28) Trying to make drones into an “iPhone Style” project(37:39) Why Seasats is focused on endurance and staying power more than launches(39:15) The complexities of working with fuel cells(42:27) The importance of beautiful design even when working on government technology(45:51) Why they’re building Seasats in beautiful San Diego, CA(47:29) The challenge of getting entirely free from Chinese components(53:52) “The Power of Small Things Has Changed”(55:18) The “wildly negative” ROI on most humanoid robotics companies also applies to maritime tech(59:09) Why there are so few defense nets against people with tiny but agile drones(01:02:32) FOUNDER Q’s: Is a founder working 24/7 a red flag?(01:10:11) How bad is it to use VC money to pay off credit cards?(01:12:49) A look at Cursor’s unique recruitment strategy.(01:19:57) Should young VCs go to startup conferences?Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com/Check out the TWIST500: https://twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcp*Follow Lon:X: https://x.com/lons*Follow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelm/*Thank you to our partners:(9:16) LinkedIn Ads: Start converting your B2B audience into high quality leads today. Launch your first campaign and get $250 FREE when you spend at least $250. Go to http://linkedin.com/thisweekinstartups to claim your credit.(19:07) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(31:11) Pilot - Visit https://www.pilot.com/twist and get $1,200 off your first year.

12-03
01:25:54

Is $MSTR over? Jason takes his victory lap. | E2216

This Week In Startups is made possible by:Quo - http://quo.com/TWiSTSquarespace - https://www.Squarespace.com/TWISTMiro - http://miro.com/Today’s show: Michael Saylor’s Strategy play is struggling with the price of Bitcoin on a steep decline… Is his new “dollar reserve” the answer?On TWiST, we’re looking into the state of $MSTR and why Jason remains SO skeptical about this increasingly convoluted financial scheme.Is CNBC giving Michael Saylor a pass? Is that why he won’t go on “All-In”? And do investors realize that loans go BEFORE equity? We’re asking the TOUGH questions…PLUS Jason’s Four Red Flags for companies with convoluted tactics… Why S&P Global downgraded Tether, and why Jason thinks the US government waited TOO LONG to pass stablecoin regulations… Jason reacts to the NYT “hit piece” on Bestie David Sacks… we’re checking out the new Matic robot vacuum and Sunday Robotics’ Memo bot… PLUS much more of the day’s biggest tech news and stories.Timestamps:(03:04) Why Jason broke his “No Demo Day” rule for the LAUNCH 35 Accelerator(07:08) What we can learn from BitcoinTreasuries.net about the marketplace(07:42) Why Jason remains SO skeptical on $MSTR… and any sufficiently convoluted financial scheme…(7:56) Jason’s Four Red Flags for rogue companies and financial schemes(9:49) Quo (formerly OpenPhone) gives you a clean, modern way to handle every customer call, text, and thread all in one place. Try it free at http://quo.com/TWiST(14:31) When loans go before equity, and how this can dilute your investment!(18:05) Is CNBC giving Michael Saylor a pass? Why Jason thinks he won’t go on “All-In.”(19:30) Checking in with Polymarket’s thoughts on potential MicroStrategy Bitcoin sales(20:21) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://squarespace.com/twist(22:58) Speaking of complex schemes… why S&P Global downgraded Tether(29:26) Is Tether too good to be true, as an investment?(25:17) Why Jason thinks the US waited too long to pass stablecoin regulations.(30:24) Miro - Help your teams get great done with Miro. Check out http://miro.com to find out how!(36:15) Jason’s reaction to the NYT piece about Bestie David Sacks(43:14) Is there a growing divide within the GOP about how to engage with tech companies?(44:04) What are “Glue Employees” and why are they important?(45:03) How to tell your “Glue Employees” apart from the “union reps” and other rabble rousers…(51:50) Sunday Robotics: another human-ish robot but with WHEELS (and a baseball cap)(56:05) We’re checking out the Matic robot vacuum as well… Should these products be combined?*Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com/Check out the TWIST500: https://twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcp*Follow Lon:X: https://x.com/lons*Follow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelm/*Follow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanis/*Thank you to our partners:(9:49) Quo (formerly OpenPhone) gives you a clean, modern way to handle every customer call, text, and thread all in one place. Try it free at http://quo.com/TWiST(20:21) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://squarespace.com/twist(30:24) Miro - Help your teams get great done with Miro. Check out http://miro.com to find out how!Great TWIST interviews: Will Guidarahttps://youtu.be/pvJa2pzuXWQEoghan McCabehttps://youtu.be/9dHN4YFkgv4Steve Huffmanhttps://podcasts.apple.com/us/podcast/reddit-ceo-steve-huffman-on-mod-revolt-building-a/id315114957?i=1000617333424Brian Cheskyhttps://podcasts.apple.com/ca/podcast/airbnb-ceo-brian-chesky-on-early-rejection-customer/id315114957?i=1000611761112

12-02
57:40

SO MANY THINGS need to go right just so you can watch a TikTok! | E2215

Register here to join Founder University Japan’s kickoff! 👉🏻 https://luma.com/cm0x90mkToday’s show: On TWiST, Alex is chatting with Neubird CEO Gou Rao about the intricate complexity of IT Ops, and the vast amount of layers and components that have to be delivered very quickly to your phone in order to stream a simple video clip.Neubird has developed Hawkeye, an AI “engineer” that uses “context engineering” to isolate and troubleshoot problems, while still keeping costs down. Loading up a video to show your friends may SOUND straightforward, but it’s actually, as Alex notes, a miracle anything on the internet works at all.PLUS we’ve got Subject AI CEO Michael Vilardo stopping by to tell us how the app uses gamification to keep kids learning and engaged. NOTE TO FOUNDERS: Mike got invited on the show because he sends email updates to his “dream investors,” including Jason. It’s a solid best practice!Finally, we’re flashing back to a remarkably prescient 2019 interview with then-Scale AI chief Alexandr Wang, who tells us why he thinks the AI Doomsday scenarios — AND the elaborate AGI promises — are both way overblown.Timestamps:(3:19) Neubird asks: What if we took AI tools and applied them to IT ops?(5:17) Why does IT ops seem to get so much more complicated over time?(6:14) Gou walks us through all the various components that need to be delivered when you post a simple TikTok video(8:41) Why agentic systems (like Hawkeye) are the ideal tool for monitoring metrics, logs, traces and alerts(10:05) CLA - Get started with CLA's CPAs, consultants, and wealth advisors now at https://claconnect.com/tech(11:17) How is IT Ops different from Site Reliability Engineering (SRE)?(12:36) Is Hawkeye an AI Agent or an “Engineer”? How we decide what to call our “co-pilot.”(16:07) How “context engineering” helps Hawkeye isolate problems, and keeps inference costs down(17:27) Is Hawkeye plug and play? Or does it need to be trained on a specific system?(18:59) How Neubird measures Hawkeye’s overall effectiveness(19:59) Perspective AI: Real insights, straight from your customers, and your first two months are on us. Just go to http://getperspective.ai/twist(21:47) Hawkeye can diagnose and make recommendations, or go in and fix the problem itself, if you like!(24:27) What Gou thinks about the pace of AI innovation: Has it slowed? Are we in a lull?(25:41) LLMs already have a lot of knowledge, but how do we enhance their EQ?(28:58) TIP FOR FOUNDERS: Send updates to your “dream” investors! That’s how Mike got on the show!(30:20) Uber AI Solutions - Your trusted partner to get AI to work in the real world. Book a demo with them TODAY at https://Uber.com/twist⁠(31:21) The importance of branding… Why Mike pivoted to Subject.ai(33:43) How Subject helps bring teachers and students together for more 1-on-1 interaction(35:48) Mike walks us through how Subject works, and how gamification keeps kids engaged(39:56) Is anything lost when an AI grades a student’s test, rather than a human?(42:09) Subject can serve as a “teacher of record” in classrooms(46:28) Why Mike and Subject AI are back in the office(47:40) TWIST FLASHBACK with Alexandr Wang of Scale AI from November 2019(53:10) Alexandr explains AI to Jason (back when it was still called “Machine Learning”)(1:01:08) How AI will help people focus on “higher-value work”(1:04:48) Why Alexandr thinks apocalyptic AI scenarios are unrealistic(1:13:28) Are the big promises around AGI overblown?*Thank you to our partners:(10:05) CLA - Get started with CLA's CPAs, consultants, and wealth advisors now at https://claconnect.com/tech(19:59) Perspective AI: Real insights, straight from your customers, and your first two months are on us. Just go to http://getperspective.ai/twist(30:20) Uber AI Solutions - Your trusted partner to get AI to work in the real world. Book a demo with them TODAY at https://Uber.com/twist

11-26
01:15:55

Even great startups sometimes need to pivot (feat. Francisco Cornejo of Theo) | E2214

Register here for Founder University Japan’s Kickoff 👉🏻 https://luma.com/cm0x90mkToday’s show:The team from Familify had released a well-reviewed storytelling app for kids and parents… but it just wasn’t growing!Then they noticed that Bible stories and faith-based content was particularly popular. So they decided released a brand new app, Theo, just for these sorts of lessons and stories. And the new product overtook Storybook in just a few weeks!It’s a vital lesson for founders… Even if you succeed, you may be able to succeed EVEN MORE. Remain flexible and open to strong new ideas (especially if, like Francisco, your wife suggests them!)PLUS we’re chatting with Collin from En Vérité about how AI can make do diligence much less painful for investors AND checking out our latest Gamma Pitch Deck competitor. Find out why Jason says Jake Triton from Pitch Prfct might just be closing in on Product Market Fit.Timestamps:(5:20) How Storybook, then Theo was motivated by a children’s mental health crisis(5:46) Despite great reviews, Storybook wasn’t growing! Here’s what they did.(7:13) The Power of Experiments: Theo overtook Storybook in popularity in JUST WEEKS(10:04) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(11:04) Digging in to the decision to flip from all stories to Bible stories(12:34) The difference in how users perceive prayer vs. meditation(14:06) Will they make different Theos for different denominations of Christianity? Other faiths?(14:55) Jason makes the case for the Theo app and its team(19:59) Sentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWIST(21:50) Key lessons for founders from Francisco’s pitch today(26:51) Collin Sebastian from En Vérité joins the show to tell us how En Vérité helps prepare founders for the due diligence process(30:00) Enterpret: Enterpret turns feedback noise into Customer Intelligence, so your team knows exactly what to fix and build next. Head to Enterpret.com/twist to book a demo and see it in action.(31:03) Jason recalls some diligence horror stories from his past(32:14) Where En Vérité gets their data and how they use it(36:39) What Collin learned from his time at SoftBank(39:44) The Gamma Pitch Deck Competition returns with Jake Triton from PitchPrfct [https://x.com/JakeTriton] @pitchprfctsms(42:29) Why Jason thinks Jake is closing in on Product Market Fit(45:51)How PitchPrfct plans to have AI help build your campaign and workflowSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:04) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(19:59) Sentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWIST(30:00) Enterpret: Enterpret turns feedback noise into Customer Intelligence, so your team knows exactly what to fix and build next. Head to Enterpret.com/twist to book a demo and see it in action.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartups

11-24
51:48

Jason predicts a “major M&A moment” in the next six months! | E2213

Register here to join Founder University Japan’s kickoff: https://luma.com/cm0x90mkToday’s show:Google and Meta had their cases dismissed (or received a slap on the wrist)… Despite all the backlash and cynicism, AI companies continue making bank and releasing hot new products… What does it all mean?For Jason Calacanis, the signs are pointing to a “major M&A moment,” with huge opportunities for increased efficiency and consolidation among America’s favorite brands and largest companies?Who will it be? Join Jason and Alex for a round of hot speculation.PLUS why Jason thinks Michael Burry is both right and wrong about GPU depreciation, why NOTHING is certain about these OpenAI mega-deals, Google’s Nano Banana Pro can make infographics and they’re VERY impressive… and much more.Timestamps:(1:54) Jason’s calling in from Vegas… He’s doing a hot lap at F1!(3:18) How restaurants are becoming the new Hot IP(6:50) Founder University is heading to TOKYO!(9:27) Why Jason thinks the future of startups is truly global(10:06) Pipedrive - Bring your entire sales process into one elegant space. Get started with a 30 day free trial at pipedrive.com/twist(11:39) Nvidia killed it on the numbers… but what are the vibes around AI? Jason sounds off.(13:05) Why nothing is certain when it comes to the Nvidia/OpenAI deal(19:40) Is Google now WINNING consumer adoption of AI? How did it get this close?(19:57) Crusoe Cloud: Crusoe is the AI factory company. Reliable infrastructure and expert support. Visit https://crusoe.ai/build to reserve your capacity for the latest GPUs today.(26:07) Meanwhile, AI apps are still dominating the iOS Store(27:09) Why Jason and Alex think Michael Burry’s both right and wrong about GPU depreciation(30:13) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(37:46) We’re testing out Nano Banana Pro on a BBQ infographic challenge(43:42) What a week for AI models! It doesn’t seem like things are slowing down…(46:12) Kalshi is growing fast, but can it catch Polymarket?(47:50) Is a rate cut coming? Jason and Alex read the tea leaves.(50:13) Why Jason predicts a “major M&A moment” in the next six months(52:09) VIEWER QUESTION: What should a software engineer be working on RIGHT NOW.(54:02) Founder Friday is now… STARTUP SUPPER CLUBSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:06) Pipedrive - Bring your entire sales process into one elegant space. Get started with a 30 day free trial at pipedrive.com/twist(19:57) Crusoe Cloud: Crusoe is the AI factory company. Reliable infrastructure and expert support. Visit https://crusoe.ai/build to reserve your capacity for the latest GPUs today.(30:13) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com

11-22
55:35

Why data is the biggest AI bottleneck (feat. Arthur Mensch of Mistral AI) | E2212

Today’s show:The race for more compute gets all the headlines, but Mistral AI CEO Arthur Mensch tells us the REAL danger is running out of data!On TWiST, Jason and Alex are chatting with the head of France’s largest foundation AI company, Mistral AI, about how enterprises can get more out of their AI pilots, whether the West is lacking leadership on open-source, why Mistral AI isn’t pursuing every possible kind of AI application, and optimizing your models for performance rather than benchmarks (aka benchmaxxing). Find out what it’s like to run a huge AI company in today’s intense environment!PLUS… why everyone made the wrong call on OpenAI vs. Google… Kraken’s fresh $20 billion valuation… Jason’s urgent message to every company thinking about M&A… and much more!Timestamps:(3:35) Why did everyone get it wrong on Google vs. OpenAI?(10:51) Why Jason thinks drone delivery will make everyone safer(9:52) SQUARESPACE: Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(11:26) Mistral AI CEO Arthur Mensch joins us! What’s it like to run a foundation model AI company in this intense environment?(14:50) Why enterprises aren’t getting enough value out of AI and how Mistral AI aims to correct this(18:45) Why Mistral AI’s goal is, ultimately, to disappear…(20:19) LinkedIn Ads: Start converting your B2B audience into high quality leads today. Launch your first campaign and get $250 FREE when you spend at least $250. Go to http://linkedin.com/thisweekinstartups to claim your credit.(22:49) Are Europe and the US lacking leadership on open source AI?(24:53) Mistral AI doesn’t need to compete in every category... how big of an advantage is focus?(27:05) The “two bottlenecks” in Machine Learning: Compute and Data(29:01) How Mistral AI works with human experts to annotate their models, and where they source them from(30:06) Nexos.ai: Stop Shadow AI in its tracks with the unified platform for secure AI adoption and productivity. Try it with a free 14-day trial at https://nexos.ai/twist.(34:24) Is optimizing your model for benchmark tests (aka benchmaxxing) like cheating?(40:08) Will we ever be able to run smaller AI models on our phones?(44:21) When does Arthur think we’ll have truly helpful humanoid robots in our lives?(49:42) Suno lawsuits and why Jason says you should NEVER break the rules, ESPECIALLY with the music industry(54:28) Release the Kraken! They’re now worth $20 billion.(56:48) Jason is going to F1… should he take up the offer and do a dry run?(58:30) How Meta beat the FTC and why Jason is so excited about it(1:01:37) Who should buy Crunchbase?

11-20
01:05:13

AI Model Showdown: Grok 4.1 vs. Gemini 3 | E2211

AI Model Showdown: Grok 4.1 vs. Gemini 3 | E2211Register for Founder University Japan’s Kickoff! https://luma.com/cm0x90mkToday’s show:*Will the arrival of two hotly-anticipated, intensely powerful AI models snap the Doomer cycle?On a new TWiST, Jason and Alex consider the current AI landscape, one where cynicism about insider mega-deals, fear of job displacement, and concerns about bubble bursts seem to rule the day. Will the arrival of two powerful new models — xAI’s Grok 4.1 and Google’s Gemini 3 — help the industry to course-correct? And how do we decide how much these models have improved anyway?PLUS we’re investigating Cloudflare’s recent downtime and their acquisition of Replicate. Are we heading toward a future in which everyone runs their own models, locally? And how worried should founders get if their products or sites go down for a few hours?Finally, if you’re an investor, and want to come to Jason’s Dim Sum Demo Day in San Francisco, here’s the link: http://launch.co/dimsumTimestamps:(2:01) Why the internet got broadly degraded when Cloudflare went down(5:00) How worried should founders become when their sites go offline?(6:44) Downtime aside, what did Cloudflare want with Replicate?(8:12) Why Jason predicts one day we’ll run our own local language models(9:39) Goldbelly - Goldbelly ****ships America’s most delicious, iconic foods nationwide! Get 20% off your first order by going to Goldbelly.com and using the promo code TWiST at checkout.(15:25) How to turn off “Learn From This App” on your iPhone(17:29) Will the arrival of hotly-anticipated new models stop the spread of Doomerism and AI cynicism(20:00) Every.io - For all of your incorporation, banking, payroll, benefits, accounting, taxes or other back-office administration needs, visit every.io.(23:53) Checking back in with the “Best AI Model” Polymarket… why has ChatGPT dropped so low?(29:43) Zite - Zite is the fastest way to build business software with AI. Build apps, forms, websites and portals that connect to the tools you already use. Go to zite.com/twist to get started.(31:14) ANOTHER AI mega-deal? Nvidia and Microsoft are investing in… ANTHROPIC(33:06) Why so many AI deals now include “up to…” language around investments(35:04) What Jason thinks of Dario Amodei’s warning about white collar job displacement(39:39) If we all agree AI job displacement is coming… what can be done?(45:16) All about Jason’s Dim Sum Investor Demo Day in San Francisco!Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(9:39) Goldbelly - Goldbelly ****ships America’s most delicious, iconic foods nationwide! Get 20% off your first order by going to Goldbelly.com and using the promo code TWiST at checkout.(20:00) Every.io - For all of your incorporation, banking, payroll, benefits, accounting, taxes or other back-office administration needs, visit every.io.(29:43) Zite - Zite is the fastest way to build business software with AI. Build apps, forms, websites and portals that connect to the tools you already use. Go to zite.com/twist to get started.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

11-19
46:45

Archer buys an airport, Ramp’s huge raise, RIP KitKat, Bezos returns to the C-Suite, and more | E2210

*Are we finally reaching Peak eVTOL? Jason and Alex on Joby’s big Abu Dhabi moves and Archer’s purchase of LA’s Hawthorne Airport.On a PACKED Monday TWiST, Jason is BACK from MENA and Tokyo. Hear tales from his whirlwind trips launching new Founder University satellite programs… and find out why construction and fintech are BOOMING across the Middle East.PLUS Ramp raised $300M… here’s why Alex calls the round “pretty baller.” We question why AI companies are growing SO MUCH FOUNDER than their SaaS counterparts. We’re digging into the Problem with Dropbox.AND we’re saying goodbye to KitKat, the beloved SF bodega cat who was reportedly run over by a Waymo. Here’s why Jason’s not too broken up about it (but he’s JUST JOKING!)👉  Register here for Founder University Japan’s kickoff: https://luma.com/cm0x90mkToday’s show:Timestamps:(2:17) Big takeaways from Jason’s MENA Founder University trip(6:54) Why construction and fintech are booming across the Middle East(9:56) Netsuite. The business landscape is very chaotic right now. That’s why you need NetSuite, by Oracle. Download the CFO’s Guide to AI and Machine Learning for free at https://www.netsuite.com/twist(12:35) Everything was very different at Founder University Japan! It’s coming in January.(15:59) Ramp raised $300M at a $32B valuation… why Alex says it’s “pretty baller”(17:15) Ramp says AI agents are making money more intelligent… the heck does that mean?(19:26) We’re building more space for machines than humans now… and why Jason’s not sure this will last(19:48) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(23:41) Why AI is growing SO MUCH faster than even top SaaS companies(25:32) The Problem with Dropbox…(30:21) DevStats - DevStats integrates your dev work and your business goals into a shared language that everyone can understand. Get 20% off, plus access to their dedicated Slack channel. Just go to https://www.DevStats.com/twist.(32:39) Jason ate his way across Tokyo… here’s all the deets(33:16) RIP KitKat, beloved SF bodega cat killed by a Waymo(39:03) So who SHOULD get to make decisions about local roads?(44:15) Dario Amodei from Anthropic shares Jason’s concerns about AI job displacement(52:02) What’s going on with crypto prices? Is this vibe-based? Just based on the wider economy?(58:14) Viewer questions: What strategies should founders employ in the current fundraising landscape?(1:02:42) Bezos RETURNS to the C-Suite. What IS “Project Prometheus”?(1:10:24) Jason thinks Bezos still returns to Amazon at some point… or runs for President.Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(9:56) Netsuite. The business landscape is very chaotic right now. That’s why you need NetSuite, by Oracle. Download the CFO’s Guide to AI and Machine Learning for free at https://www.netsuite.com/twist(19:48) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(30:21) DevStats - DevStats integrates your dev work and your business goals into a shared language that everyone can understand. Get 20% off, plus access to their dedicated Slack channel. Just go to https://www.DevStats.com/twist.Check out Jason’s suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com

11-18
01:14:15

Stop ghosting your friends with Nox’s RPLY, plus Alloy Automation and a Shopify flashback | E2209

👉 Register here to join Founder University Japan’s kickoff: https://luma.com/cm0x90mkToday’s show:Nox’s new app RPLY reminds you to text your friends back, getting you to iMessage inbox zero.On today’s TWiST, we’ve got Molly Cantillon of Nox, telling us how she plans to make lackadaisical texters (like our co-host Alex) more effective, even if it means breaking into Apple’s walled garden. Hear about how RPLY maps your relationships so that it can understand your messages contextually, and help you stay organized.Then, Gregg Mojica of Alloy Automation swings by the show to dispel some common myths about AI agents. For the most part, these little machine learning helps aren’t truly autonomous… Hear how Alloy’s agents decide when it’s time to bring in a human for help. PLUS is AI in a “lull” right now? Hear why Gregg thinks there’s still a LOT of room for these apps to improve.Finally, it’s another TWiST Flashback. We’re jumping back to 2013 for an eye-opening chat between Jason and Shopify founder/CEO Tobi Lutke. Hear some fascinatingly prescient takes on the rise of SaaS, how early Shopify differentiated itself from other ecommerce and website building solutions, AND why Tobi dreamed of making Ottawa a true tech hub.Timestamps:(02:57) Molly Cantillon of Nox is trying to help you get better at texting(04:01) How RPLY gets even chaotic texters like Alex more organized(05:10) The complexities of entering into Apple’s “walled garden”(07:20) Keeping RPLY safe, in case you’re using it for work!(09:24) Miro - Help your teams get great done with Miro. Check out miro.com to find out how!(11:59) How RPLY uses relationship mapping to understand and prioritize your messages(19:23) Perspective AI - Real insights, straight from your customers, and your first two months are on us. Just go to getperspective.ai/twist.(21:08) Why Nox wants its AI to become “the Invisible OS.”(29:30) Pilot - Visit https://www.pilot.com/twist and get $1,200 off your first year.(30:40) We’ve got Gregg Mojica of AI agent makers Alloy Automation(31:42) How the rise of AI agents changed the core of Gregg’s business(34:03) Why most AI agents still aren’t truly autonomous(35:00) How Alloy’s agents decide when to bring in a human for help(37:02) Why the rapid acceleration of AI development has made some enterprises pump the brakes(39:00) Is AI in a “lull” right now? Why Gregg thinks there’s still room to improve.(40:31) How close are we to AI apps going truly mainstream?(43:41) Why Alloy Automation didn’t raise a massive round like so many of its AI peers? (Or are they?!)(46:48) The difficulty of hiring in today’s AI landscape(50:21) In today’s TWiST Flashback, we’re revisiting Tobi Lutke of Shopify’s appearance from way back in 2013!(52:11) Why Shopify switched from selling snowboards to storefronts(59:37) Turning Ottawa into a tech hub, and the “secondary market” theory(1:05:32)The constant tension between growing your global footprint and expanding your features(1:08:52)Who were Shopify’s actual rivals?

11-14
01:13:31

Why We Need Ferries and Tugboats in Space w/ Orbital Operations | E2208

👉 Register here to join the kickoff: https://luma.com/cm0x90mkToday’s show:Just getting our stuff into orbit isn’t enough… Orbital Operations wants to help companies take things HIGHER.In today’s TWiST 500 interview, Alex chats with Ben Schleuniger, whose startup Orbital Operations is solving the complexity of space logistics. The advent of reusable rockets has made it easier and cheaper than ever for us to place objects in Low Earth Orbit (or LEO).But what if we want to reach higher orbits? That’s a much more challenging issue: space is already kind of CROWDED, and not all of our vehicles can carry enough fuel to power them that far out into the cosmos.Orbital’s fix? Cryogenic orbital maneuvering vehicles (or OMVs) like the Astraeus, which uses hyper-efficient propulsion systems, allowing them to travel further and faster speeds, and even potentially get refueled in orbit.Learn more about this fascinating tech PLUS we’re looking back at classic Jason interviews with Greg Brockman of OpenAI and Vlad Tenev of Robinhood, AND checking in with Oliver’s latest This Week in AI demo for Character AI’s blockbuster conversational chatbots.Timestamps:(02:56) Alex opens the show with Ben Schleuniger, co-founder of space tech startup Orbital Operations(03:47) Why is movement within orbit such a challenging problem?(4:28) The key importance of launch vehicle reusability(07:05) How Orbital’s Astreaus vehicle utilizes cryogenic propellants… and why(08:49) The secret to keeping those propellants cool(10:04) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(13:57) How Orbital is preparing for their Series A, and how they plan to spend the cash(20:37) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(28:09) TWiST FLASHBACK: Revisiting OpenAI Greg Brockman’s visit from 2018(31:31) LinkedIn Ads: Start converting your B2B audience into high quality leads today. Launch your first campaign and get $250 FREE when you spend at least $250. Go to http://linkedin.com/thisweekinstartups to claim your credit.(37:57) How GPUs unlocked the AI revolution(35:02) Tackling early concerns about deepfakes(41:17) Looking ahead to the dawn of AGI(50:05) AI DEMO: Oliver stops by to walk us through Character AI’s key features(50:51) Watch as Oliver simulates a chat with former President Barack Obama(53:30) How to use ChatGPT to enhance your Character AI prompts(56:57) TWIST FLASHBACK with Robinhood’s Vlad Tenev from May 2017(57:14) Back then, Robinhood was valued at a mere $1.3 billion!(59:21) How Robinhood made financial transactions SO MUCH FASTER than they used to be(1:00:57) When Robinhood realized they had Product Market Fit… via Hacker News!(1:06:44) The magic of being better, faster, and cheaper(1:08:12) This segment was filmed BEFORE Robinhood offered crypto(1:11: 08) Jason’s Eagle Computer Speech and how to avoid “Taj Mahal Syndrome”Check out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmThank you to our partners:Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWISTNorthwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!LinkedIn Ads: Start converting your B2B audience into high quality leads today. Launch your first campaign and get $250 FREE when you spend at least $250. Go to http://linkedin.com/thisweekinstartups to claim your credit.

11-13
01:13:56

Baneshi Space

yes , I am first person comment in this episode.

07-10 Reply

Paja Storec

💚WATCH>>ᗪOᗯᑎᒪOᗩᗪ>>👉https://co.fastmovies.org

01-15 Reply

Bethel chase

im a future creator and inventor and i want be creating anything around trap or hiphop music not even a beat nor tech nothing professor i dont wanna talk about that music

05-23 Reply

Bethel chase

what does this have to do with technology first of all anybody like music called trap is an idiot cut that out

05-23 Reply

saber fun

very goodf

01-16 Reply

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