Thorax Podcast

Interstitial lung disease (ILD) can be considered an umbrella term for a large number of conditions involving inflammation and scarring in the lungs. It can come from a range of causes, including occupational exposures such as asbestosis or silicosis, environmental factors like animal exposure, or idiopathic pulmonary issues. The diagnosis and management of the disease can vary from region to region, and its prevalence is increasing around the world. Social media editor Dr. Kate Diomede is joined by the associate editors Sheetu Singh¹ and Nazia Chaudhuri², who have commissioned a series of articles on ILD in Thorax. Read the articles: State of the art review: Holistic management of symptom burden in ILD Challenging the status quo for clinical trials in fibrotic interstitial lung diseases Treatable traits in interstitial lung disease: towards precision medicine Breaking with Convention: The role of lymphocytes in IPF Epithelial damage and ageing: the perfect storm Global perspective on pulmonary fibrosis: epidemiology, regional variations, gaps in care, and future directions 1. Director ILD & Pulmonary Rehab Clinic, Rajasthan Hospital, Jaipur, India; Thorax associate editor ILD  2. Consultant Respiratory Medicine & Senior Clinical Lecturer, Ulster University, Northern Ireland; Chair of British Thoracic Society ILD Registry; Thorax associate editor ILD Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.

Previous trials on triple therapy inhaler use (ETHOS and IMPACT) were understood to show a reduction in mortality in COPD patients. However, a reanalysis published in Thorax shows that this benefit may have been misattributed. Host Dr. Kate Diomede is joined by the paper's authors, pharmacist Kari Leung¹ and physician Prof. Aroon Hingorani², both members of the ​North Central London Joint Formulary committee. Read the paper: Inhaled corticosteroid withdrawal and mortality rate in trials of triple therapy inhalers for COPD Further reading: Withdrawal of fluticasone propionate from combined salmeterol/fluticasone treatment in patients with COPD causes immediate and sustained disease deterioration: a randomised controlled trial 1. UCL Hospitals NHS Foundation Trust, London, UK 2. University College London, London, UK Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.

In this episode, Thorax social media editor Dr. Kate Diomede speaks to Dr. Susan Muiser¹, author of a research paper based on the NOVELTY study that included over 12,000 patients globally with asthma, COPD, or asthma plus COPD. The research sought to find potential biomarkers that could link to exacerbations in these patients, giving consideration to blood eosinophils and fractional exhaled nitric oxide as possible candidates which could give insight into disease progression and treatment response.   Read the paper: Association of blood eosinophils and exhaled nitric oxide with exacerbations in patients with asthma, COPD and asthma+COPD: the NOVELTY study 1. Department of Pulmonology, University Medical Centre Groningen, Groningen, Netherlands   Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.

Last year the British Thoracic Society published the results of their 2024 survey of trainees. Since then, a number of commentary pieces have been published in Thorax, and two authors join the podcast this episode. Dr. Abigail MacKintosh¹ a respiratory medicine trainee, and Dr. Daniel Smith², consultant and chair of the BTS workforce committee, join host Dr. Kate Diomede to discuss some of the issues identified  and some potential solutions. Links: British Thoracic Society trainee survey 2024: what are the trainees saying and how will this impact the future workforce? Commentary on the 2024 British Thoracic Society Specialty Trainee Survey report  The British Thoracic Society Trainee Survey Report 2024 (1) Respiratory Medicine, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK (2)  Sherwood Forest Hospitals NHS Foundation Trust, Nottinghamshire, UK Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.

This journal club episode is guest-hosted by Dr. David Furfaro and Dr. Kristina Montemayor of the PulmPEEPs, in conversation with Thorax education editor Dr. Christopher Turnbull, and Dr. George Doumat, author of a recent journal club article focussing on the theme of bronchiectasis. These papers highlight the exciting progress that is being seen in the treatment of this condition, and the challenges that remain ahead. Links: Journal club Phase 3 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis Cathepsin C (dipeptidyl peptidase 1) inhibition in adults with bronchiectasis: AIRLEAF, a phase II randomised, double-blind, placebo-controlled, dose-finding study Five-Year Outcomes among U.S. Bronchiectasis and NTM Research Registry Patients Anxiety, depression, physical disease parameters and health-related quality of life in the BronchUK national bronchiectasis cohort   For more from the PulmPEEPs, visit their podcast's website. You can find them Twitter (@PulmPEEPs) and Instagram (pulmpeeps), and hear past episodes on Apple Podcasts and Spotify. To submit a journal club article of your own, you can contact Chris directly - [email protected] Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.